S. Duijst BSc publications

2021

• Shi Xiaoxia, Aronson Sem J., ten Bloemendaal Lysbeth, Duijst Suzanne, Bakker Robert S., de Waart Dirk R., Bortolussi Giulia, Collaud Fanny, Oude Elferink Ronald P., Muro Andrés F., Mingozzi Federico, Ronzitti Giuseppe, Bosma Piter J. Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients Molecular therapy. Methods & clinical development 2021;20:287-297
• Chang Jung-Chin, Go Simei, Gilglioni Eduardo H., Duijst Suzanne, Panneman Daan M., Rodenburg Richard J., Li Hang Lam, Huang Hsu-Li, Levin Lonny R., Buck Jochen, Verhoeven Arthur J., Oude Elferink Ronald P. J. Soluble adenylyl cyclase regulates the cytosolic NADH/NAD+ redox state and the bioenergetic switch between glycolysis and oxidative phosphorylation BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 2021;1862 (4) [PubMed]

2020

• Aronson Sem J., Bakker Robert S., Moenis Sascha, van Dijk Remco, Bortolussi Giulia, Collaud Fanny, Shi Xiaoxia, Duijst Suzanne, ten Bloemendaal Lysbeth, Ronzitti Giuseppe, Muro Andrés F., Mingozzi Federico, Beuers Ulrich, Bosma Piter J. A Quantitative In Vitro Potency Assay for Adeno-Associated Virus Vectors Encoding for the UGT1A1 Transgene Molecular therapy. Methods & clinical development 2020;18:250-258 [PubMed]
• Roscam Abbing Reinout L. P., Slijepcevic Davor, Donkers Joanne M., Havinga Rick, Duijst Suzanne, Paulusma Coen C., Kuiper Johan, Kuipers Folkert, Groen Albert K., Oude Elferink Ronald P. J., van de Graaf Stan F. J. Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice Hepatology (Baltimore, Md.) 2020;71 (1):247-258 [PubMed]

2019

• Aronson Sem J., Bakker Robert S., Shi Xiaoxia, Duijst Suzanne, ten Bloemendaal Lysbeth, de Waart Dirk R., Verheij Joanne, Ronzitti Giuseppe, Oude Elferink Ronald P., Beuers Ulrich, Paulusma Coen C., Bosma Piter J. Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice Journal of hepatology 2019;71 (1):153-162 [PubMed]

2018

• Koelink Pim J., Wildenberg Manon E., Stitt Larry W., Feagan Brian G., Koldijk Martin, van 't Wout Angélique B., Atreya Raja, Vieth Michael, Brandse Johannan F., Duijst Suzanne, te Velde Anje A., D'Haens Geert R. A. M., Levesque Barrett G., van den Brink Gijs R. Development of reliable, valid and responsive scoring systems for endoscopy and histology in animal models for inflammatory bowel disease Journal of Crohn s & colitis 2018;12 (7):794-803 [PubMed]
• Gilglioni Eduardo H., Chang Jung Chin, Duijst Suzanne, Go Simei, Adam Aziza A. A. , Hoekstra Ruurdtje, Verhoeven Arthur J., Ishii-Iwamoto Emy L., Oude Elferink Ronald P. J. Improved oxygenation dramatically alters metabolism and gene expression in cultured primary mouse hepatocytes Hepatology Communications 2018;2 (3):299-312 [PubMed]

2017

• van Dijk Remco, Aronson Sem J., de Waart Dirk R., van de Graaf Stan F., Duijst Suzanne, Seppen Jurgen, Oude Elferink Ronald, Beuers Ulrich, Bosma Piter J. Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo Scientific reports 2017;7 (1):1646 [PubMed]
• Hakvoort Theodorus B. M., He Youji, Kulik Wim, Vermeulen Jacqueline L. M., Duijst Suzanne, Ruijter Jan M., Runge Jurgen H., Deutz Nicolaas E. P., Koehler S. Eleonore, Lamers Wouter H. Pivotal Role of Glutamine Synthetase in Ammonia Detoxification Hepatology (Baltimore, Md.) 2017;65 (1):281-293 [PubMed]

2016

• de Waart Dirk R., Naik Jyoti, Utsunomiya Karina S., Duijst Suzanne, Ho-Mok Kam, Bolier A. Ruth, Hiralall Johan, Bull Laura N., Bosma Piter J., Oude Elferink Ronald P. J., Paulusma Coen C. ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes Hepatology (Baltimore, Md.) 2016;64 (1):161-174 [PubMed]
• van der Mark Vincent A., de Jonge Hugo R., Chang Jung-Chin, Ho-Mok Kam S., Duijst Suzanne, Vidović Dragana, Carlon Marianne S., Oude Elferink Ronald P. J., Paulusma Coen C. The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 2016;1863 (9):2280-2288 [PubMed]

2015

• Naik Jyoti, de Waart Dirk R., Utsunomiya Karina, Duijst Suzanne, Mok Kam Ho, Oude Elferink Ronald P. J., Bosma Piter J., Paulusma Coen C. ATP8B1 and ATP11C: Two Lipid Flippases Important for Hepatocyte Function Digestive diseases (Basel, Switzerland) 2015;33 (3):314-318 [PubMed]
• Slijepcevic Davor, Kaufman Christina, Wichers Catharina G. K., Gilglioni Eduardo H., Lempp Florian A., Duijst Suzanne, de Waart Dirk R., Elferink Ronald P. J. Oude, Mier Walter, Stieger Bruno, Beuers Ulrich, Urban Stephan, van de Graaf Stan F. J. Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice Hepatology (Baltimore, Md.) 2015;62 (1):207-219 [PubMed]

2014

• Jansen Robert S., Duijst Suzanne, Mahakena Sunny, Sommer Daniela, Szeri Flóra, Váradi András, Plomp Astrid, Bergen Arthur A., Oude Elferink Ronald P. J., Borst Piet, van de Wetering Koen ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report Arteriosclerosis, thrombosis, and vascular biology 2014;34 (9):1985-1989 [PubMed]
• Kunne Cindy, Acco Alexandra, Duijst Suzanne, de Waart Dirk R., Paulusma Coen C., Gaemers Ingrid, Oude Elferink Ronald P. J. FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2014;1842 (5):739-746 [PubMed]
• Kunne Cindy, de Graaff Marijke, Duijst Suzanne, de Waart Dirk R., Oude Elferink Ronald P. J., Paulusma Coen C. Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis Laboratory investigation; a journal of technical methods and pathology 2014;94 (10):1103-1113 [PubMed]
• El Filali Ebtisam, Duijst Suzanne, Hiralall Johan K., Legrand Nicolas, van Gulik Thomas, Hoekstra Ruurdtje, Seppen Jurgen Human fetal liver cells for regulated ex vivo erythropoietin gene therapy Molecular therapy. Methods & clinical development 2014;1:UNSP 14003 [PubMed]
• Montenegro-Miranda P. S., Pichard V., Aubert D., ten Bloemendaal L., Duijst S., de Waart D. R., Ferry N., Bosma P. J. In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV Gene therapy 2014;21 (2):168-174 [PubMed]

2013

• Montenegro-Miranda Paula S., Pañeda Astrid, ten Bloemendaal Lysbeth, Duijst Suzanne, de Waart Dirk R., Aseguinolaza Gloria Gonzalez, Bosma Piter J. Adeno-associated viral vector serotype 5 poorly transduces liver in rat models PLoS ONE 2013;8 (12):e82597 [PubMed]
• Kunne Cindy, Acco Alexandra, Hohenester Simon, Duijst Suzanne, de Waart Dirk R., Zamanbin Alaleh, Oude Elferink Ronald P. J. Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity Hepatology (Baltimore, Md.) 2013;57 (4):1509-1517 [PubMed]
• van Dijk Remco, Montenegro-Miranda Paula S., Riviere Christel, Schilderink Ronald, ten Bloemendaal Lysbeth, van Gorp Jacqueline, Duijst Suzanne, de Waart Dirk R., Beuers Ulrich, Haisma Hidde J., Bosma Piter J. Polyinosinic acid blocks adeno-associated virus macrophage endocytosis in vitro and enhances adeno-associated virus liver-directed gene therapy in vivo Human gene therapy 2013;24 (9):807-813 [PubMed]

2012

• Folmer Dineke E., Mok Kam S., de Wee Sebastiaan W., Duijst Suzanne, Hiralall Johan K., Seppen Jurgen, Oude Elferink Ronald P. J., Paulusma Coen C. Cellular Localization and Biochemical Analysis of Mammalian CDC50A, a Glycosylated beta-subunit for P4 ATPases journal of histochemistry and cytochemistry 2012;60 (3):205-218 [PubMed]
• Montenegro-Miranda Paula S., Sneitz Nina, de Waart D. Rudi, ten Bloemendaal Lysbeth, Duijst Suzanne, de Knegt Robert J., Beuers Ulrich, Finel Moshe, Bosma Piter J. Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822 (8):1223-1229 [PubMed]
• de Waart Dirk R., van de Wetering Koen, Kunne Cindy, Duijst Suzanne, Paulusma Coen C., Oude Elferink Ronald P. J. Oral Availability of Cefadroxil Depends on ABCC3 and ABCC4 Drug metabolism and disposition: the biological fate of chemicals 2012;40 (3):515-521 [PubMed]
• Sokolović Aleksandar, Montenegro-Miranda Paula S., de Waart Dirk Rudi, Cappai Radha M. N., Duijst Suzanne, Sokolović Milka, Bosma Piter J. Overexpression of insulin like growth factor binding protein 5 reduces liver fibrosis in chronic cholangiopathy BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822 (6):996-1003 [PubMed]