S.I. Bouwman-Gringhuis PhD publications

2020

• Stunnenberg Melissa, van Pul Lisa, Sprokholt Joris K., van Dort Karel A., Gringhuis Sonja I., Geijtenbeek Teunis B. H., Kootstra Neeltje A. MAVS genetic variation is associated with decreased HIV-1 replication in vitro and reduced cd4+ t cell infection in HIV-1-infected individuals Viruses 2020;12 (7) [PubMed]
• Stunnenberg Melissa, Sprokholt Joris K., van Hamme John L., Kaptein Tanja M., Zijlstra-Willems Esther M., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Synthetic Abortive HIV-1 RNAs Induce Potent Antiviral Immunity Frontiers in immunology 2020;11 [PubMed]

2019

• Sprokholt Joris K. Dengue virus infection of dendritic cells: Sensing viral replication during inflammation and immunity 2019. 191p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)

2018

• Stunnenberg Melissa, Geijtenbeek Teunis B. H., Gringhuis Sonja I. DDX3 in HIV-1 infection and sensing: A paradox Cytokine & growth factor reviews 2018;40:32-39 [PubMed]
• Hertoghs Nina Molecular mechanisms controlling dendritic cell functions in HIV-1 and Ebolavirus infection 2018. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)

2017

• Gringhuis Sonja I., Hertoghs Nina, Kaptein Tanja M., Zijlstra-Willems Esther M., Sarrami-Fooroshani Ramin, Sprokholt Joris K., van Teijlingen Nienke H., Kootstra Neeltje A., Booiman Thijs, van Dort Karel A., Ribeiro Carla M. S., Drewniak Agata, Geijtenbeek Teunis B. H. HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 Nature immunology 2017;18 (2):225-235 [PubMed]
• Gringhuis Sonja I., Hertoghs Nina, Kaptein Tanja M., Zijlstra-Willems Esther M., Sarrami-Fooroshani Ramin, Sprokholt Joris K., van Teijlingen Nienke H., Kootstra Neeltje A., Booiman Thijs, van Dort Karel A., Ribeiro Carla M. S., Drewniak Agata, Geijtenbeek Teunis B. H. HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 (vol 18, pg 225, 2017) Nature immunology 2017;18 (4):474 [PubMed]
• Wilbers Ruud H. P., Westerhof Lotte B., van Noort Kim, Obieglo Katja, Driessen Nicole N., Everts Bart, Gringhuis Sonja I., Schramm Gabriele, Goverse Aska, Smant Geert, Bakker Jaap, Smits Hermelijn H., Yazdanbakhsh Maria, Schots Arjen, Hokke Cornelis H. Production and glyco-engineering of immunomodulatory helminth glycoproteins in plants Scientific reports 2017;7:45910 [PubMed]
• Sprokholt Joris K., Kaptein Tanja M., van Hamme John L., Overmars Ronald J., Gringhuis Sonja I., Geijtenbeek Teunis B. H. RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production PLoS pathogens 2017;13 (11):e1006738 [PubMed]
• Sprokholt Joris K., Kaptein Tanja M., van Hamme John L., Overmars Ronald J., Gringhuis Sonja I., Geijtenbeek Teunis B. H. RIG-I-like Receptor Triggering by Dengue Virus Drives Dendritic Cell Immune Activation and TH1 Differentiation Journal of immunology (Baltimore, Md. 2017;198 (12):4764-4771 [PubMed]

2016

• Geijtenbeek Teunis B. H., Gringhuis Sonja I. C-type lectin receptors in the control of T helper cell differentiation Nature reviews. Immunology 2016;16 (7):433-448 [PubMed]
• Ribeiro Carla M. S., Sarrami-Forooshani Ramin, Setiawan Laurentia C., Zijlstra-Willems Esther M., van Hamme John L., Tigchelaar Wikky, van der Wel Nicole N., Kootstra Neeltje A., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets Nature 2016;540 (7633):448-452 [PubMed]

2015

• Hertoghs Nina, van der Aar Angelic M. G., Setiawan Laurentia C., Kootstra Neeltje A., Gringhuis Sonja I., Geijtenbeek Teunis B. H. SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1 Journal of immunology (Baltimore, Md. 2015;194 (9):4431-4437 [PubMed]

2014

• Davis Meredith E., Wang May K., Rennick Linda J., Full Florian, Gableske Sebastian, Mesman Annelies W., Gringhuis Sonja I., Geijtenbeek Teunis B. H., Duprex W. Paul, Gack Michaela U. Antagonism of the Phosphatase PP1 by the Measles Virus V Protein Is Required for Innate Immune Escape of MDA5 Cell host & microbe 2014;16 (1):19-30 [PubMed]
• Wevers Brigitte A. C-type lectin signaling in dendritic cells. Molecular control of antifungal inflammation 2014. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)
• Gringhuis Sonja I., Kaptein Tanja M., Wevers Brigitte A., van der Vlist Michiel, Klaver Elsenoor J., van Die Irma, Vriend Lianne E. M., de Jong Marein A. W. P., Geijtenbeek Teunis B. H. Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production Nature communications 2014;5:5074 [PubMed]
• Gringhuis Sonja I., Kaptein Tanja M., Wevers Brigitte A., Mesman Annelies W., Geijtenbeek Teunis B. H. Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation Nature communications 2014;5:3898 [PubMed]
• Wevers Brigitte A., Kaptein Tanja M., Zijlstra-Willems Esther M., Theelen Bart, Boekhout Teun, Geijtenbeek Teunis B. H., Gringhuis Sonja I. Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity Cell host & microbe 2014;15 (4):494-505 [PubMed]
• Mesman Annelies W. Host-pathogen interplay in viral transmission and immune evasion 2014. 163p. ISBN 9789461824165. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)
• Mesman Annelies W., Zijlstra-Willems Esther M., Kaptein Tanja M., de Swart Rik L., Davis Meredith E., Ludlow Martin, Duprex W. Paul, Gack Michaela U., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Measles Virus Suppresses RIG-I-like Receptor Activation in Dendritic Cells via DC-SIGN-Mediated Inhibition of PP1 Phosphatases Cell host & microbe 2014;16 (1):31-42 [PubMed]

2013

• Geijtenbeek Teunis B. H., Gringhuis Sonja I. An inside job for antibodies: tagging pathogens for intracellular sensing Nature immunology 2013;14 (4):309-311 [PubMed]
• Wevers Brigitte A., Geijtenbeek Teunis B. H., Gringhuis Sonja I. C-type lectin receptors orchestrate antifungal immunity Future microbiology 2013;8 (7):839-854 [PubMed]

2012

• van den Berg Linda M., Gringhuis Sonja I., Geijtenbeek Teunis B. H. An evolutionary perspective on C-type lectins in infection and immunity Annals of the New York Academy of Sciences 2012;1253:149-158 [PubMed]
• van der Vlist Michiel C-type lectins on dendritic cells. Bittersweet interactions with viruses 2012. 151p. ISBN 9789085708308. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)
• Gringhuis Sonja I., Kaptein Tanja M., Wevers Brigitte A., Theelen Bart, van der Vlist Michiel, Boekhout Teun, Geijtenbeek Teunis B. H. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1 beta via a noncanonical caspase-8 inflammasome Nature immunology 2012;13 (3):246-U63 [PubMed]

2011

• van der Vlist Michiel, van der Aar Angelic M. G., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Innate signaling in HIV-1 infection of dendritic cells Current opinion in HIV and AIDS 2011;6 (5):348-352 [PubMed]
• Gringhuis Sonja I., Wevers Brigitte A., Kaptein Tanja M., van Capel Toni M. M., Theelen Bart, Boekhout Teun, de Jong Esther C., Geijtenbeek Teunis B. H. Selective C-Rel Activation via Malt1 Controls Anti-Fungal T-H-17 Immunity by Dectin-1 and Dectin-2 PLoS pathogens 2011;7 (1):e1001259 [PubMed]

2010

• Gringhuis Sonja I., Geijtenbeek Teunis B. H. Carbohydrate signaling by C-type lectin DC-SIGN affects NF-kappaB activity Methods in enzymology 2010;480:151-164 [PubMed]
• den Dunnen Jeroen, Gringhuis Sonja I., Geijtenbeek Teunis B. H. Dusting the sugar fingerprint: C-type lectin signaling in adaptive immunity Immunology letters 2010;128 (1):12-16 [PubMed]
• Gringhuis Sonja I., van der Vlist Michiel, van den Berg Linda M., den Dunnen Jeroen, Litjens Manja, Geijtenbeek Teunis B. H. HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells Nature immunology 2010;11 (5):419-U81 [PubMed]

2009

• Gringhuis Sonja I., den Dunnen Jeroen, Litjens Manja, van der Vlist Michiel, Geijtenbeek Teunis B. H. Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori Nature immunology 2009;10 (10):1081-U58 [PubMed]
• den Dunnen Jeroen C-type lectin signaling in response to pathogens 2009. 194p. ISBN 9789085702863. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: van Kooyk Y.; Co-supervisors: Geijtenbeek T. B. H., Gringhuis S. I.)
• Gringhuis Sonja I., den Dunnen Jeroen, Litjens Manja, van der Vlist Michiel, Wevers Brigitte, Bruijns Sven C. M., Geijtenbeek Teunis B. H. Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk Nature immunology 2009;10 (2):203-213 [PubMed]
• den Dunnen Jeroen, Gringhuis Sonja I., Geijtenbeek Teunis B. H. Innate signaling by the C-type lectin DC-SIGN dictates immune responses Cancer immunology, immunotherapy 2009;58 (7):1149-1157 [PubMed]
• Geijtenbeek Teunis B. H., den Dunnen Jeroen, Gringhuis Sonja I. Pathogen recognition by DC-SIGN shapes adaptive immunity Future microbiology 2009;4 (7):879-890 [PubMed]
• Geijtenbeek Teunis B. H., Gringhuis Sonja I. Signalling through C-type lectin receptors: shaping immune responses Nature reviews. Immunology 2009;9 (7):465-479 [PubMed]

2008

• García-Vallejo Juan J., van Liempt Ellis, da Costa Martins Paula, Beckers Cora, van het Hof Bert, Gringhuis Sonja I., Zwaginga Jaap-Jan, van Dijk Willem, Geijtenbeek Teunis B. H., van Kooyk Yvette, van Die Irma DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2 Molecular immunology 2008;45 (8):2359-2369 [PubMed]
• Hovius Joppe W. R., de Jong Marein A. W. P., den Dunnen Jeroen, Litjens Manja, Fikrig Erol, van der Poll Tom, Gringhuis Sonja I., Geijtenbeek Teunis B. H. Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization PLoS pathogens 2008;4 (2):e31 [PubMed]
• de Jong Marein A. W. P., de Witte Lot, Oudhoff Menno J., Gringhuis Sonja I., Gallay Philippe, Geijtenbeek Teunis B. H. TNF-alpha and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo Journal of clinical investigation 2008;118 (10):3440-3452 [PubMed]

2007

• Gringhuis Sonja I., den Dunnen Jeroen, Litjens Manja, van het Hof Bert, van Kooyk Yvette, Geijtenbeek Teunis B. H. C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB Immunity 2007;26 (5):605-616 [PubMed]
• van Vliet Sandra J., den Dunnen Jeroen, Gringhuis Sonja I., Geijtenbeek Teunis Bh, van Kooyk Yvette Innate signaling and regulation of Dendritic cell immunity Current opinion in immunology 2007;19 (4):435-440 [PubMed]
• Schreibelt Gerty, Kooij Gijs, Reijerkerk Arie, van Doorn Ruben, Gringhuis Sonja I., van der Pol Susanne, Weksler Babette B., Romero Ignacio A., Couraud Pierre-Olivier, Piontek Jörg, Blasig Ingolf E., Dijkstra Christine D., Ronken Eric, de Vries Helga E. Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling FASEB journal 2007;21 (13):3666-3676 [PubMed]

2006

• García-Vallejo Juan J., van Dijk Willem, van het Hof Bert, van Die Irma, Engelse Marten A., van Hinsbergh Victor W. M., Gringhuis Sonja I. Activation of human endothelial cells by tumor necrosis factor-alpha results in profound changes in the expression of glycosylation-related genes Journal of cellular physiology 2006;206 (1):203-210 [PubMed]
• van Rietschoten Johanna G. I., Verzijlbergen Kitty F., Gringhuis Sonja I., van der Pouw Kraan Tineke C. T. M., Bayley Jean-Pierre, Wierenga Eddy A., Jones Peter A., Kooter Jan M., Verweij Cor L. Differentially methylated alleles in a distinct region of the human interleukin-1alpha promoter are associated with allele-specific expression of IL-1alpha in CD4+ T cells Blood 2006;108 (7):2143-2149 [PubMed]
• Kasperkovitz Pia V. From genomics to STAT-1 in Rheumatoid Arthritis 2006. 143p. ISBN 9789090205779. [UvA Dissertations Online] Vrije Universteit Amsterdam: MCBI. (Supervisor: Verweij C. L.; Co-supervisors: Gringhuis S. I., van der Pouw Kraan C. T. M.)
• García-Vallejo Juan J., Gringhuis Sonja I., van Dijk Willem, van Die Irma Gene expression analysis of glycosylation-related genes by real-time polymerase chain reaction Methods in molecular biology (Clifton, N.J.) 2006;347:187-209 [PubMed]
• van Vliet Sandra J., Gringhuis Sonja I., Geijtenbeek Teunis B. H., van Kooyk Yvette Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45 Nature immunology 2006;7 (11):1200-1208 [PubMed]

2005

• Gringhuis Sonja I., García-Vallejo Juan Jesús, van het Hof Bert, van Dijk Willem Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolin Molecular and cellular biology 2005;25 (15):6454-6463 [PubMed]
• Vallejo J. J. G. The regulation of glycosylation in the endothelium 2005. 269p. ISBN 9789090195735. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: Kraal G.; Co-supervisors: van Dijk W., Gringhuis S. I.)
• García-Vallejo Juan Jesús, van Dijk Willem, van Die Irma, Gringhuis Sonja I. Tumor necrosis factor-alpha up-regulates the expression of beta1,4-galactosyltransferase I in primary human endothelial cells by mRNA stabilization Journal of biological chemistry 2005;280 (13):12676-12682 [PubMed]

2004

• Remans Philip H. J., Gringhuis Sonja I., van Laar Jacob M., Sanders Marjolein E., Papendrecht-van der Voort Ellen A. M., Zwartkruis Fried J. T., Levarht E. W. Nivine, Rosas Marcela, Coffer Paul J., Breedveld Ferdinand C., Bos Johannes L., Tak Paul P., Verweij Cornelis L., Reedquist Kris A. Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytes Journal of immunology (Baltimore, Md. 2004;173 (2):920-931 [PubMed]

2002

• Gringhuis Sonja I., Papendrecht-van der Voort Ellen A. M., Leow Angela, Nivine Levarht E. W., Breedveld Ferdinand C., Verweij Cornelis L. Effect of redox balance alterations on cellular localization of LAT and downstream T-cell receptor signaling pathways Molecular and cellular biology 2002;22 (2):400-411 [PubMed]
• Gringhuis Sonja I., Breedveld Ferdinand C., Verweij Cornelis L. Linker for activation of T cells: sensing redox imbalance Methods in enzymology 2002;352:248-257 [PubMed]
• Verweij Cornelis L., Gringhuis Sonja I. Oxidants and tyrosine phosphorylation: role of acute and chronic oxidative stress in T-and B-lymphocyte signaling Antioxidants & redox signaling 2002;4 (3):543-551 [PubMed]

2000

• Gringhuis S. I., Leow A., Papendrecht-van der Voort E. A., Remans P. H., Breedveld F. C., Verweij C. L. Displacement of linker for activation of T cells from the plasma membrane due to redox balance alterations results in hyporesponsiveness of synovial fluid T lymphocytes in rheumatoid arthritis Journal of immunology (Baltimore, Md. 2000;164 (4):2170-2179 [PubMed]

1999

• Maurice M. M., Nakamura H., Gringhuis S., Okamoto T., Yoshida S., Kullmann F., Lechner S., van der Voort E. A., Leow A., Versendaal J., Muller-Ladner U., Yodoi J., Tak P. P., Breedveld F. C., Verweij C. L. Expression of the thioredoxin-thioredoxin reductase system in the inflamed joints of patients with rheumatoid arthritis Arthritis and rheumatism 1999;42 (11):2430-2439 [PubMed]

1998

• Borger P., Vellenga E., Gringhuis S. I., Timmerman J. A., Lummen C., Postma D. S., Kauffman H. F. Prostaglandin E2 differentially modulates IL-5 gene expression in activated human T lymphocytes depending on the costimulatory signal Journal of allergy and clinical immunology 1998;101 (2 Part 1):231-240 [PubMed]
• Gringhuis S. I., de Leij L. F., Coffer P. J., Vellenga E. Signaling through CD5 activates a pathway involving phosphatidylinositol 3-kinase, Vav, and Rac1 in human mature T lymphocytes Molecular and cellular biology 1998;18 (3):1725-1735 [PubMed]

1997

• Gringhuis S. I., de Leij L. F., Verschuren E. W., Borger P., Vellenga E. Interleukin-7 upregulates the interleukin-2-gene expression in activated human T lymphocytes at the transcriptional level by enhancing the DNA binding activities of both nuclear factor of activated T cells and activator protein-1 Blood 1997;90 (7):2690-2700 [PubMed]
• Gringhuis S. I., de Leij L. F., Wayman G. A., Tokumitsu H., Vellenga E. The Ca2+/calmodulin-dependent kinase type IV is involved in the CD5-mediated signaling pathway in human T lymphocytes Journal of biological chemistry 1997;272 (50):31809-31820 [PubMed]
• Calkhoven C. F., Gringhuis S. I., AB G. The chicken CCAAT/enhancer binding protein alpha gene. Cloning, characterisation and tissue distribution Gene 1997;196 (1-2):219-229 [PubMed]