M. Riool PhD publications

foto

Publications M. Riool PhD

Position
Other Academic Staff
Main activities
Education, Research
Specialisation
Experimental bacteriology
Focus of research

Biomaterial-associated infections and novel antimicrobial strategies

 

Infections of biomedical devices, or “biomaterials” (catheters, prosthetic heart valves, implants), are a major and increasing problem in modern medicine, especially in view of the increase in antibiotic resistance. We have discovered that bacteria do not only colonize the medical device by biofilm-formation, but also persist in surrounding tissue, due to disturbed local immunity. Bacterial, biomaterial, and host-responses involved in the pathogenesis are subject of studies, in order to find novel approaches for treatment and prevention.


Previously involved in the Dutch NANTICO (Non-adherent ANTImicrobial Coatings) consortium, focused on the development of different antimicrobial coating strategies to prevent biomaterial-associated infections, and in the European FP7 project Biofilm Alliance (BALI), where we developed novel Synthetic Antimicrobial and Anti-biofilm Peptides.


Currently involved in the STW project CRANIOSAFE, aiming to develop innovative antimicrobial materials for skull reconstructions, and the NEWPOL project SuperActiv, developing supramolecular biomaterials with antimicrobial and regenerative activity.

 

2020

  • Dunne C. P., Askew P. D., Papadopoulos T., Gouveia I. C., Ahonen M., Modic M., Azevedo N. F., Schulte S., Cosemans P., Kahru A., Murzyn K., Keevil C. W., Riool M., Keinänen-Toivola M. M. Antimicrobial coating innovations to prevent infectious disease: a consensus view from the AMiCl COST Action Journal of hospital infection 2020;105 (2):116-118 [PubMed]
  • Hofstee Marloes I., Muthukrishnan Gowrishankar, Atkins Gerald J., Riool Martijn, Thompson Keith, Morgenstern Mario, Stoddart Martin J., Richards Robert G., Zaat Sebastian A. J., Moriarty Thomas F. Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods American journal of pathology 2020;190 (6):1151-1163 [PubMed]
  • Riool Martijn, de Breij Anna, Kwakman Paulus H. S., Schonkeren-Ravensbergen Elisabeth, de Boer Leonie, Cordfunke Robert A., Malanovic Nermina, Drijfhout Jan W., Nibbering Peter H., Zaat Sebastian A. J. Thrombocidin-1-derived antimicrobial peptide TC19 combats superficial multi-drug resistant bacterial wound infections BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2020;1862 (8) [PubMed]

2019

  • Ramstedt Madeleine, Ribeiro Isabel A. C., Bujdakova Helena, Mergulhão Filipe J. M., Jordao Luisa, Thomsen Peter, Alm Martin, Burmølle Mette, Vladkova Todorka, Can Fusun, Reches Meital, Riool Martijn, Barros Alexandre, Reis Rui L., Meaurio Emilio, Kikhney Judith, Moter Annette, Zaat Sebastian A. J., Sjollema Jelmer Evaluating Efficacy of Antimicrobial and Antifouling Materials for Urinary Tract Medical Devices: Challenges and Recommendations Macromolecular bioscience 2019;19 (5):e1800384 [PubMed]
  • van de Vijfeijken S. E. C. M., Groot C., Ubbink D. T., Vandertop W. P., Depauw P. R. A. M., Nout E., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., Hoefnagels F. W. A., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Riool M., Zaat S. A. J. Factors related to failure of autologous cranial reconstructions after decompressive craniectomy Journal of cranio-maxillo-facial surgery 2019;47 (9):1420-1425 [PubMed]
  • Moriarty T. Fintan, Harris Llinos G., Mooney Robert A., Wenke Joseph C., Riool Martijn, Zaat Sebastian A. J., Moter Annette, Schaer Thomas P., Khanna Nina, Kuehl Richard, Alt Volker, Montali Andrea, Liu Jianfeng, Zeiter Stephan, Busscher Henk J., Grainger David W., Richards R. Geoff Recommendations for design and conduct of preclinical in vivo studies of orthopedic device-related infection Journal of orthopaedic research 2019;37 (2):271-287 [PubMed]
  • Koppen Bruce C., Mulder Patrick P. G., de Boer Leonie, Riool Martijn, Drijfhout Jan W., Zaat Sebastian A. J. Synergistic microbicidal effect of cationic antimicrobial peptides and teicoplanin against planktonic and biofilm-encased Staphylococcus aureus International journal of antimicrobial agents 2019;53 (2):143-151 [PubMed]
  • van de Vijfeijken S. E. C. M., Schreurs R., Dubois L., Becking A. G., van de Vijfeijken S. E. C. M., Schreurs R., Dubois L., Becking A. G., Schreurs R., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J. The use of cranial resection templates with 3D virtual planning and PEEK patient-specific implants: A 3 year follow-up Journal of cranio-maxillo-facial surgery 2019;47 (4):542-547 [PubMed]

2018

  • Zaccaria Sabrina, van Gaal Ronald C., Riool Martijn, Zaat Sebastian A. J., Dankers Patricia Y. W. Antimicrobial peptide modification of biomaterials using supramolecular additives Journal of Polymer Science, Part A: Polymer Chemistry 2018;56 (17):1926-1934 [PubMed]
  • Münker T. J. A. G., van de Vijfeijken S. E. C. M., Mulder C. S., Vespasiano V., Becking A. G., Kleverlaan C. J., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J. Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices Journal of the mechanical behavior of biomedical materials 2018;81:168-172 [PubMed]
  • Omardien Soraya, Drijfhout Jan W., van Veen Henk, Schachtschabel Soraya, Riool Martijn, Hamoen Leendert W., Brul Stanley, Zaat Sebastian A. J. Synthetic antimicrobial peptides delocalize membrane bound proteins thereby inducing a cell envelope stress response BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2018;1860 (11):2416-2427 [PubMed]
  • de Breij Anna, Riool Martijn, Cordfunke Robert A., Malanovic Nermina, de Boer Leonie, Koning Roman I., Ravensbergen Elisabeth, Franken Marnix, van der Heijde Tobias, Boekema Bouke K., Kwakman Paulus H. S., Kamp Niels, El Ghalbzouri Abdelouahab, Lohner Karl, Zaat Sebastian A. J., Drijfhout Jan W., Nibbering Peter H. The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms Science translational medicine 2018;10 (423):eaan4044 [PubMed]

2017

  • Riool M., Dirks A. J., Jaspers V., de Boer L., Loontjens T. J., van der Loos C. M., Florquin S., Apachitei I., Rijk L. N., Keul H. A., Zaat S. A. A chlorhexidine-releasing epoxy-based coating on titanium implants prevents Staphylococcus aureus experimental biomaterial-associated infection European cells & materials 2017;33:143-157 [PubMed]
  • Riool Martijn, de Breij Anna, Drijfhout Jan W., Nibbering Peter H., Zaat Sebastian A. J. Antimicrobial Peptides in Biomedical Device Manufacturing Frontiers in chemistry 2017;5:63 [PubMed]
  • Riool Martijn, de Breij Anna, de Boer Leonie, Kwakman Paulus H. S., Cordfunke Robert A., Cohen Or, Malanovic Nermina, Emanuel Noam, Lohner Karl, Drijfhout Jan W., Nibbering Peter H., Zaat Sebastian A. J. Controlled Release of LL-37-Derived Synthetic Antimicrobial and Anti-Biofilm Peptides SAAP-145 and SAAP-276 Prevents Experimental Biomaterial-Associated Staphylococcus aureus Infection Advanced functional materials 2017;27 (20):1606623
  • van Hengel Ingmar A. J., Riool Martijn, Fratila-Apachitei Lidy E., Witte-Bouma Janneke, Farrell Eric, Zadpoor Amir A., Zaat Sebastian A. J., Apachitei Iulian Data on the surface morphology of additively manufactured Ti-6Al-4V implants during processing by plasma electrolytic oxidation Data in brief 2017;13:385-389 [PubMed]
  • Fidan S., Muhaffel F., Riool M., Cempura G., de Boer L., Zaat S. A. J., Filemonowicz A. Czyrska-, Cimenoglu H. Fabrication of oxide layer on zirconium by micro-arc oxidation: Structural and antimicrobial characteristics Materials science and engineering. C: Materials for biological applications 2017;71:565-569 [PubMed]
  • Riool Martijn Novel antibacterial strategies to combat biomaterial-associated infection 2017. 264p. ISBN 9789462996625. [UvA Dissertations Online] University of Amsterdam. (Supervisor: de Jong M. D.; Co-supervisor: Zaat S. A. J.)
  • van Hengel Ingmar A. J., Riool Martijn, Fratila-Apachitei Lidy E., Witte-Bouma Janneke, Farrell Eric, Zadpoor Amir A., Zaat Sebastian A. J., Apachitei Iulian Selective laser melting porous metallic implants with immobilized silver nanoparticles kill and prevent biofilm formation by methicillin-resistant Staphylococcus aureus Biomaterials 2017;140:1-15 [PubMed]

2016

  • Moriarty T. Fintan, Kuehl Richard, Coenye Tom, Metsemakers Willem-Jan, Morgenstern Mario, Schwarz Edward M., Riool Martijn, Zaat Sebastiaan A. J., Khana Nina, Kates Stephen L., Richards R. Geoff Orthopaedic device-related infection: current and future interventions for improved prevention and treatment EFORT Open Reviews 2016;1 (4):89-99 [PubMed]
  • de Breij A., Riool M., Kwakman P. H. S., de Boer L., Cordfunke R. A., Drijfhout J. W., Cohen O., Emanuel N., Zaat S. A. J., Nibbering P. H., Moriarty T. F. Prevention of Staphylococcus aureus biomaterial-associated infections using a polymer-lipid coating containing the antimicrobial peptide OP-145 Journal of controlled release 2016;222:1-8 [PubMed]

2015

  • Metsemakers Willem-Jan, Emanuel Noam, Cohen Or, Reichart Malka, Potapova Inga, Schmid Tanja, Segal David, Riool Martijn, Kwakman Paulus H. S., de Boer Leonie, de Breij Anna, Nibbering Peter H., Richards R. Geoff, Zaat Sebastian A. J., Moriarty T. Fintan A doxycycline-loaded polymer-lipid encapsulation matrix coating for the prevention of implant-related osteomyelitis due to doxycycline-resistant methicillin-resistant Staphylococcus aureus Journal of controlled release 2015;209:47-56 [PubMed]

2014

  • Cleophas Rik T. C., Riool Martijn, van Ufford H. C. Quarles, Zaat Sebastian A. J., Kruijtzer John A. W., Liskamp Rob M. J. Convenient Preparation of Bactericidal Hydrogels by Covalent Attachment of Stabilized Antimicrobial Peptides Using Thiol-ene Click Chemistry ACS MACRO LETTERS 2014;3 (5):477-480
  • Riool Martijn, de Boer Leonie, Jaspers Valery, van der Loos Chris M., van Wamel Willem J. B., Wu Gang, Kwakman Paulus H. S., Zaat Sebastian A. J. Staphylococcus epidermidis originating from titanium implants infects surrounding tissue and immune cells Acta biomaterialia 2014;10 (12):5202-5212 [PubMed]

2010

  • Zaat S. A. J., Broekhuizen C. A. N., Riool M. Host tissue as a niche for biomaterial-associated infection Future microbiology 2010;5 (8):1149-1151 [PubMed]
  • Tessadori Federico, Zeng Kang, Manders Erik, Riool Martijn, Jackson Dean, van Driel Roel Stable S/MAR-based episomal vectors are regulated at the chromatin level Chromosome research 2010;18 (7):757-775 [PubMed]

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