MD D. Brevoord publications

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Publications MD D. Brevoord

Position
PhD Candidate
Main activities
Research
Specialisation
Anesthesiology
Focus of research

Prevention of ischemia-reperfusion injury

Helium inhalation has been shown to reduce ischemia-reperfusion injury in experimental settings. We explore the effect of helium inhalation and possible aplication in humans:

  • The molecular effects of helium on the myocardium as well as the possible protective effect on organ damage during surgery (hreat, kidneys) in patients undergoing cardiac surgery.
  • The safety and feasibility of helium inhalation in patients on the ICU after out-of-hospital cardiac arrest.
  • The effects of helium inhalation on coronary hemodynamics in patients undergoing heart catheterisation.
  • The use of helium inhalation as adjuvant treatment in patient undergoing PCI for myocardial infarction.

Remote ischemic conditioning is another experimental technique to prevent reperfusion injury, in which reperfusion injury in one organ is reduced by aplying a short series of ischemia and reperfusion to another organ.

  • The molecular effects of remote ischemic conditioning on myocardium in patients undergoing cardiac surgery.
  • The use of remote ischemic conditiong for the reduction of post-operative atrial fibrillation following cardiac surgery.
Amsterdam UMC Research Institutes
AMC departments
All publications

2016

  • Smit Kirsten F., Brevoord Daniel, de Hert Stefan, de Mol Bas A., Kerindongo Raphaela P., van Dieren Susan, Schlack Wolfgang S., Hollmann Markus W., Weber Nina C., Preckel Benedikt Effect of helium pre- or postconditioning on signal transduction kinases in patients undergoing coronary artery bypass graft surgery Journal of translational medicine 2016;14 (1):294 [PubMed]
  • Brevoord Daniel, Beurskens Charlotte J. P., van den Bergh Walter M., Lagrand Wim K., Juffermans Nicole P., Binnekade Jan M., Preckel Benedikt, Horn Janneke Helium ventilation for treatment of post-cardiac arrest syndrome: A safety and feasibility study Resuscitation 2016;107:145-149 [PubMed]

2014

  • Beurskens Charlotte J., Brevoord Daniel, Lagrand Wim K., van den Bergh Walter M., Vroom Margreeth B., Preckel Benedikt, Horn Janneke, Juffermans Nicole P. Heliox Improves Carbon Dioxide Removal during Lung Protective Mechanical Ventilation Critical care research and practice 2014;2014:954814 [PubMed]

2013

  • Smit Kirsten F., Oei Gezina T. M. L., Brevoord Daniel, Stroes Erik S., Nieuwland Rienk, Schlack Wolfgang S., Hollmann Markus W., Weber Nina C., Preckel Benedikt Helium induces preconditioning in human endothelium in vivo Anesthesiology 2013;118 (1):95-104 [PubMed]

2012

  • Oei Gezina T. M. L., Smit Kirsten F., vd Vondervoort Djai, Brevoord Daniel, Hoogendijk Arjan, Wieland Catharina W., Hollmann Markus W., Preckel Benedikt, Weber Nina C. Effects of helium and air inhalation on the innate and early adaptive immune system in healthy volunteers ex vivo Journal of translational medicine 2012;10 (1):201 [PubMed]
  • Brevoord Daniel, Kranke Peter, Kuijpers Marijn, Weber Nina, Hollmann Markus, Preckel Benedikt Remote Ischemic Conditioning to Protect against Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis PLoS ONE 2012;7 (7):e42179 [PubMed]

2011

  • Brevoord Daniel, Hollmann Markus W., de Hert Stefan G., van Dongen Eric H. P. A., Heijnen Bram G. A. D. H., de Bruin Anton, Tolenaar Noortje, Schlack Wolfgang S., Weber Nina C., Dijkgraaf Marcel G. W., de Groot Joris R., de Mol Bas A. J. M., Driessen Antoine H. G., Momeni Mona, Wouters Patrick, Bouchez Stefaan, Hofland Jan, Luthen Christian, Meijer-Treschan Tanja A., Pannen Benedikt H., Preckel Benedikt Effect of Remote Ischemic Conditioning on atrial fibrillation and Outcome after coronary artery bypass grafting (RICO-trial) BMC anesthesiology 2011;11 (1):11 [PubMed]

2010

  • van Geer Michael A., Brevoord Daniel, Kuhlmann Koert F. D., Bakker Conny T., Mizuguchi Hiroyuki, Wesseling John G., ten Kate Fibo J., Gouma Dirk J., Oude Elferink Ronald P. J., Bosma Piter J. A fiber modified adenovirus vector that targets to the EphrinA2 receptor reveals enhanced gene transfer to ex vivo pancreatic cancer International journal of oncology 2010;36 (1):233-244 [PubMed]
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