MD MSc PhD R.J.T. Mocking publications

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Publications MD MSc PhD R.J.T. Mocking

Position
Other Academic Staff
Main activities
Education, Patient care, Research
Specialisation
Biological psychiatry
Focus of research

As a Postdoc I have a broad interest in applying research to personalise psychiatry and provide an evidence base for daily clinical practice.

My PhD focused on endocrinological and metabolic alterations in depression. By applying interdisciplinary and multimodal methods we linked fatty acids to HPA-axis functioning and neuroimaging. Findings, including our meta-analyses, suggest that dietary omega-3 fatty acids can improve antidepressant effectivity. This was implemented in the Dutch guidelines and the diet served at the department of psychiatry of the AMC now includes more omega-3 fatty acids. 

During my Postdoc I am involved in research on deep brain stimulation for psychiatric disorders in the Denys group. In addition I perform a literature study on physical and pharmacological restraints in hospital care.

For more information, see: https://nl.linkedin.com/in/roelmockinghttps://www.researchgate.net/profile/Roel_Mocking, or scholar.google.nl/citations?user=mB5faiwAAAAJ&hl

2020

  • Graat Ilse, van Rooijen Geeske, Mocking Roel, Vulink Nienke, de Koning Pelle, Schuurman Rick, Denys Damiaan Is deep brain stimulation effective and safe for patients with obsessive compulsive disorder and comorbid bipolar disorder? Journal of affective disorders 2020;264:69-75 [PubMed]

2019

  • Figueroa Caroline A., Cabral Joana, Mocking Roel J. T., Rapuano Kristina M., van Hartevelt Tim J., Deco Gustavo, Expert Paul, Schene Aart H., Kringelbach Morten L., Ruhé Henricus G. Altered ability to access a clinically relevant control network in patients remitted from major depressive disorder Human brain mapping 2019;40 (9):2771-2786 [PubMed]
  • Figueroa Caroline A., DeJong Hannah, Mocking Roel J. T., Fox Elaine, Rive Maaike M., Schene Aart H., Stein Alan, Ruhé Henricus G. Attentional control, rumination and recurrence of depression Journal of affective disorders 2019;256:364-372 [PubMed]
  • ter Horst D. M., Schene A. H., Figueroa C. A., Assies J., Lok A., Bockting C. L. H., Ruhé H. G., Mocking R. J. T. Cortisol, dehydroepiandrosterone sulfate, fatty acids, and their relation in recurrent depression Psychoneuroendocrinology 2019;100:203-212 [PubMed]
  • Ruhe Henricus G., Mocking Roel J. T., Figueroa Caroline A., Seeverens Paulien W. J., Ikani Nessa, Tyborowska Anna, Browning Michael, Vrijsen Janna N., Harmer Catherine J., Schene Aart H. Emotional biases and recurrence in major depressive disorder. Results of 2.5 years follow-up of drug-free cohort vulnerable for recurrence Frontiers in psychiatry 2019;10 (MAR) [PubMed]
  • Thesing C. S., Lok A., Milaneschi Y., Assies J., Bockting C. L. H., Figueroa C. A., Giltay E. J., Penninx B. W. J. H., Ruhé H. G., Schene A. H., Bot M., Mocking R. J. T. Fatty acids and recurrence of major depressive disorder: combined analysis of two Dutch clinical cohorts Acta psychiatrica Scandinavica 2019 [PubMed]
  • Geugies Hanneke, Mocking Roel J. T., Figueroa Caroline A., Groot Paul F. C., Marsman Jan-Bernard C., Servaas Michelle N., Steele J. Douglas, Schene Aart H., Ruhé Henricus G. Impaired reward-related learning signals in remitted unmedicated patients with recurrent depression Brain 2019;142 (8):2510-2522 [PubMed]
  • de Vries G.J. Posttraumatic stress disorder: Prevalence, stress hormones and metabolism 2019. 261p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Olff M.; Co-supervisor: Mocking R.J.T.)
  • Mocking Roel J. T., Denys D. A. J. P. Reactie op ‘Draagt de neurowetenschapper de nieuwe kleren van de keizer?’ Tijdschrift voor psychiatrie 2019;61 (12):914-915 [PubMed]

2018

  • Bercink Veerle, Mocking Roel J. T. Antipsychotica bij delier? Tijdschrift voor psychiatrie 2018;60 (9):644
  • Bergink Veerle, Mocking Roel Antwoord aan Tijdschrift voor psychiatrie 2018;60 (11):800
  • Mocking R. J. T., Assies J., Ruhé H. G., Schene A. H. Focus on fatty acids in the neurometabolic pathophysiology of psychiatric disorders Journal of inherited metabolic disease 2018;41 (4):597-611 [PubMed]
  • Figueroa Caroline A., Mocking Roel J. T., Mahmoud Gelera A., Koeter Maarten W., Bockting Claudi L., van der Does Willem, Ruhe Eric H. G., Schene Aart H. The measurement of cognitive reactivity to sad mood in patients remitted from major depressive disorder British journal of health psychology 2018;57 (3):313-327 [PubMed]

2017

  • Figueroa Caroline A., Mocking Roel J. T., van Wingen Guido, Martens Suzanne, Ruhé Henricus G., Schene Aart H. Aberrant default-mode network-hippocampus connectivity after sad memory-recall in remitted-depression Social cognitive and affective neuroscience 2017;12 (11):1803-1813 [PubMed]
  • Servaas Michelle N., Riese Harriëtte, Renken Remco J., Wichers Marieke, Bastiaansen Jojanneke A., Figueroa Caroline A., Geugies Hanneke, Mocking Roel Jt, Geerligs Linda, Marsman Jan-Bernard C., Aleman André, Schene Aart H., Schoevers Robert A., Ruhé Henricus G. Associations Between Daily Affective Instability and Connectomics in Functional Subnetworks in Remitted Patients with Recurrent Major Depressive Disorder Neuropsychopharmacology 2017;42 (13):2583-2592 [PubMed]
  • Mocking R. J. T., Nap T. S., Westerink A. M., Assies J., Vaz F. M., Koeter M. W. J., Ruhé H. G., Schene A. H. Biological profiling of prospective antidepressant response in major depressive disorder: Associations with (neuro)inflammation, fatty acid metabolism, and amygdala-reactivity Psychoneuroendocrinology 2017;79:84-92 [PubMed]
  • Vermeulen E., Stronks K., Visser M., Brouwer I. A., Snijder M. B., Mocking R. J. T., Derks E. M., Schene A. H., Nicolaou M. Dietary pattern derived by reduced rank regression and depressive symptoms in a multi-ethnic population: the HELIUS study European journal of clinical nutrition 2017;71 (8):987-994 [PubMed]
  • Korucuoglu Ozlem, Gladwin Thomas E., Baas Frank, Mocking Roel J. T., Ruhé Henricus G., Groot Paul F. C., Wiers Reinout W. Neural response to alcohol taste cues in youth: effects of the OPRM1 gene Addiction biology 2017;22 (6):1562-1575 [PubMed]
  • Mocking Roel J. T. Neurometabolic perspectives on depression vulnerability 2017. 355p. ISBN 9789491715150. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schene A. H.; Co-supervisors: Assies J., Ruhé H. G.)
  • de Vries Giel-Jan, Mocking Roel, Assies Johanna, Schene Aart, Olff Miranda Plasma lipoproteins in posttraumatic stress disorder patients compared to healthy controls and their associations with the HPA- and HPT-axis Psychoneuroendocrinology 2017;86:209-217 [PubMed]

2016

  • de Vries Giel-Jan, Mocking Roel, Lok Anja, Assies Johanna, Schene Aart, Olff Miranda Fatty acid concentrations in patients with posttraumatic stress disorder compared to healthy controls Journal of affective disorders 2016;205:351-359 [PubMed]
  • Medema Suzanne, Mocking Roel J. T., Koeter Maarten W. J., Vaz Frédéric M., Meijer Carin, de Haan Lieuwe, van Beveren Nico J. M., Kahn René, van Os Jim, Wiersma Durk, Bruggeman Richard, Cahn Wiepke, Myin-Germeys Inez Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls Schizophrenia bulletin 2016;42 (2):358-368 [PubMed]
  • Mocking Roel J. T., Doedens Paul Medicamenteuze behandeling van het metabool syndroom Nurse Academy GGZ : Praktijkgerichte nascholing voor GGZ-verpleegkundigen 2016 (2):29-34
  • Mocking R. J. T., Harmsen I., Assies J., Koeter M. W. J., Ruhé H. G., Schene A. H. Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder Translational psychiatry 2016;6:e756 [PubMed]
  • Vermeulen Esther, Stronks Karien, Visser Marjolein, Brouwer Ingeborg A., Schene Aart H., Mocking Roel J. T., Colpo Marco, Bandinelli Stefania, Ferrucci Luigi, Nicolaou Mary The association between dietary patterns derived by reduced rank regression and depressive symptoms over time: the Invecchiare in Chianti (InCHIANTI) study British journal of nutrition 2016;115 (12):2145-2153 [PubMed]
  • Mocking Roel J. T., Figueroa Caroline A., Rive Maria M., Geugies Hanneke, Servaas Michelle N., Assies Johanna, Koeter Maarten W. J., Vaz Frédéric M., Wichers Marieke, van Straalen Jan P., de Raedt Rudi, Bockting Claudi L. H., Harmer Catherine J., Schene Aart H., Ruhé Henricus G. Vulnerability for new episodes in recurrent major depressive disorder: protocol for the longitudinal DELTA-neuroimaging cohort study BMJ open 2016;6 (3):e009510 [PubMed]

2015

  • de Vries Giel-Jan, Lok Anja, Mocking Roel, Assies Johanna, Schene Aart, Olff Miranda Altered one-carbon metabolism in posttraumatic stress disorder Journal of affective disorders 2015;184:277-285 [PubMed]
  • Mocking R. J. T., Pellikaan C. M., Lok A., Assies J., Ruhé H. G., Koeter M. W., Visser I., Bockting C. L., Olff M., Schene A. H. DHEAS and cortisol/DHEAS-ratio in recurrent depression: State, or trait predicting 10-year recurrence? Psychoneuroendocrinology 2015;59:91-101 [PubMed]
  • Assies Johanna, Mocking Roel J. T., Lok Anja, Koeter Maarten W. J., Bockting Claudi L. H., Visser Ieke, Pouwer François, Ruhé Henricus G., Schene Aart H. Erythrocyte fatty acid profiles and plasma homocysteine, folate and vitamin B6 and B12 in recurrent depression: Implications for co-morbidity with cardiovascular disease Psychiatry research 2015;229 (3):992-998 [PubMed]
  • Mocking Roel J. T., Verburg Hanka F., Westerink Anne M., Assies Johanna, Vaz Frédéric M., Koeter Maarten W. J., Ruhé Henricus G., Schene Aart H. Fatty acid metabolism and its longitudinal relationship with the hypothalamic-pituitary-adrenal axis in major depression: Associations with prospective antidepressant response Psychoneuroendocrinology 2015;59:1-13 [PubMed]
  • Mocking Roel J. T., Schene Kiry M., Maingay-Visser Dianne A. P. G. F. Intoxicatie van een zuigeling door een Dieffenbachia Nederlands tijdschrift voor geneeskunde 2015;160:A9750 [PubMed]
  • Ruhé Henricus G., Khoenkhoen Sharina J., Ottenhof Koen W., Koeter Maarten W., Mocking Roel J. T., Schene Aart H. Longitudinal effects of the SSRI paroxetine on salivary cortisol in Major Depressive Disorder Psychoneuroendocrinology 2015;52:261-271 [PubMed]
  • Mocking R. J. Metabool syndroom in de ggz: diagnostiek, oorzaken, gevolgen en behandeling Nurse Academy GGZ : Praktijkgerichte nascholing voor GGZ-verpleegkundigen 2015;2015 (1):onbekend
  • Rive Maria M., Mocking Roel J. T., Koeter Maarten W. J., van Wingen Guido, de Wit Stella J., van den Heuvel Odile A., Veltman Dick J., Ruhé Henricus G., Schene Aart H. State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder JAMA psychiatry 2015;72 (7):687-696 [PubMed]

2014

  • Assies J., Mocking R. J. T., Lok A., Ruhé H. G., Pouwer F., Schene A. H. Effects of oxidative stress on fatty acid- and one-carbon-metabolism in psychiatric and cardiovascular disease comorbidity Acta psychiatrica Scandinavica 2014;130 (3):163-180 [PubMed]
  • Mocking Roel J. T., Wever Stephany A., Pflanz C. Patrick, Pringle Abbie, Parsons Elizabeth, McTavish Sarah F., Cowen Phil J., Harmer Catherine J., Schene Aart H. Effects of short-term varenicline administration on cortisol in healthy, non-smoking adults: a randomized, double-blind, study Psychopharmacology 2014;231 (1):143-148 [PubMed]
  • Lok A., Mocking R. J. T., Assies J., Koeter M. W., Bockting C. L., de Vries G. J. [=Giel-Jan], Visser I., Derks E. M., Kayser M., Schene A. H. The one-carbon-cycle and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in recurrent major depressive disorder; influence of antidepressant use and depressive state? Journal of affective disorders 2014;166:115-123 [PubMed]

2013

  • Mocking Roel J. T., Lok Anja, Assies Johanna, Koeter Maarten W. J., Visser Ieke, Ruhé Henricus G., Bockting Claudi L. H., Schene Aart H. Ala54Thr fatty acid-binding protein 2 (FABP2) polymorphism in recurrent depression: associations with fatty acid concentrations and waist circumference PLoS ONE 2013;8 (12):e82980 [PubMed]
  • Mocking Roel Jt, Patrick Pflanz C., Pringle Abbie, Parsons Elizabeth, McTavish Sarah F., Cowen Phil J., Harmer Catherine J. Effects of Short-Term Varenicline Administration on Emotional and Cognitive Processing in Healthy, Non-Smoking Adults: A Randomized, Double-Blind, Study Neuropsychopharmacology 2013;38 (3):476-484 [PubMed]
  • Mocking R. J. T., Schene A. H. In het kort: Interventie voor gewichtsverlies effectief bij patiënten met ernstige psychiatrische aandoeningen Nederlands tijdschrift voor geneeskunde 2013;157:A6446
  • Lok A., Bockting C. L. H., Koeter M. W. J., Snieder H., Assies J., Mocking R. J. T., Vinkers C. H., Kahn R. S., Boks M. P., Schene A. H. Interaction between the MTHFR C677T polymorphism and traumatic childhood events predicts depression Translational psychiatry 2013;3:e288 [PubMed]
  • Mocking Roel J. T., Ruhé Henricus G., Assies Johanna, Lok Anja, Koeter Maarten W. J., Visser Ieke, Bockting Claudi L. H., Schene Aart H. Relationship between the hypothalamic-pituitary-adrenal-axis and fatty acid metabolism in recurrent depression Psychoneuroendocrinology 2013;38 (9):1607-1617 [PubMed]
  • Bockting C. L. H., Mocking R. J., Lok A., Koeter M. W. J., Schene A. H. Therapygenetics: the 5HTTLPR as a biomarker for response to psychological therapy? Molecular psychiatry 2013;18 (7):744-745 [PubMed]

2012

  • Assies H., Mocking R. J. T. Associatie tussen metabool syndroom en psychiatrische ziekten: focus op vetzuren en het oxidatief metabolisme. Een overzicht van de huidige stand van zaken. Psyfar : Praktische nascholing over pscyhofarmacologie 2012;1:16-23
  • Mocking Roel J. T., Assies Johanna, Koeter Maarten W. J., Ruhé Henricus G., Lok Anja, Schene Aart H. Bimodal Distribution of Fatty Acids in Recurrent Major Depressive Disorder Biological psychiatry 2012;71 (1):E3-E5 [PubMed]
  • Mocking Roel J. T., Assies Johanna, Bot Mariska, Jansen Eugene H. J. M., Schene Aart H., Pouwer François Biological Effects of Add-On Eicosapentaenoic Acid Supplementation in Diabetes Mellitus and Co-Morbid Depression: A Randomized Controlled Trial PLoS ONE 2012;7 (11):e49431 [PubMed]
  • Lok Anja, Mocking Roel J. T., Ruhé Henricus G., Visser Ieke, Koeter Maarten W. J., Assies Johanna, Bockting Claudi L. H., Olff Miranda, Schene Aart H. Longitudinal hypothalamic-pituitary-adrenal axis trait and state effects in recurrent depression Psychoneuroendocrinology 2012;37 (7):892-902 [PubMed]
  • Mocking Roel J. T., Assies Johanna, Lok Anja, Ruhé Henricus G., Koeter Maarten W. J., Visser Ieke, Bockting Claudi L. H., Schene Aart H. Statistical Methodological Issues in Handling of Fatty Acid Data: Percentage or Concentration, Imputation and Indices Lipids 2012;47 (5):541-547 [PubMed]
  • Lok Anja, Assies Johanna, Koeter Maarten W. J., Bockting Claudi L. H., Wouters Luuk F., Mocking Roel J. T., Schene Aart H. Sustained medically unexplained physical symptoms in euthymic patients with recurrent depression: Predictive value for recurrence and associations with omega 3- and 6 fatty acids and 5-HTTLPR? Journal of affective disorders 2012;136 (3):604-611 [PubMed]

2011

  • Assies Johanna, Mocking Roel J. T., Pouwer François Maternal depression and child development after prenatal DHA supplementation JAMA 2011;305 (4):360; author reply 360-360; author reply 361 [PubMed]

2010

  • Assies Johanna, Pouwer François, Lok Anja, Mocking Roel J. T., Bockting Claudi L. H., Visser Ieke, Abeling Nico G. G. M., Duran Marinus, Schene Aart H. Plasma and Erythrocyte Fatty Acid Patterns in Patients with Recurrent Depression: A Matched Case-Control Study PLoS ONE 2010;5 (5):e10635 [PubMed]