MD PhD J.J.T.H. Roelofs publications

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Publications MD PhD J.J.T.H. Roelofs

Position
Medical Specialist
Main activities
Patient care, Research
Specialisation
Pathologist
Focus of research

Reciprocal interactions between coagulation and inflammation in the context of kidney diseases.

Current research programmes:

  1. The fibrinolytic system in renal disease
  2. Active Protein C (APC) and the endothelial protein C receptor (EPCR) in acute kidney injury and renal allograft rejection
  3. APC and EPCR in antiphospholipid antibody-induced renal thrombotic microangiopathy
  4. Platelets and platelet-derived microparticles (PMP) in acute kidney injury and renal allograft rejection

2020

  • Ding Chao, Scicluna Brendon P., Stroo Ingrid, Yang Jack, Roelofs Joris J. TH, de Boer Onno J., de Vos Alex F., Nürnberg Peter, Revenko Alexey S., Crosby Jeff, van't Veer Cornelis, van der Poll Tom Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice Journal of pathology 2020;250 (1):95-106 [PubMed]

2019

  • d'Hooghe Julia N S, Goorsenberg Annika W M, Ten Hacken Nick H T, Weersink Els J M, Roelofs Joris J T H, Mauad Thais, Shah Pallav L, Annema Jouke T, Bonta Peter I Airway smooth muscle reduction after bronchial thermoplasty in severe asthma correlates with FEV1 Clinical and experimental allergy 2019;49 (4):541-544 [PubMed]
  • Bouatou Yassine, Nguyen Tri Q., Roelofs Joris J. T. H., Bemelman Frederike J., Michielsen Laura, Goldschmeding Roel, Kers Jesper, Florquin Sandrine A Multicenter Application of the 2018 Banff Classification for BK Polyomavirus-associated Nephropathy in Renal Transplantation Transplantation 2019;103 (12):2692-2700 [PubMed]
  • Uil Melissa, Scantlebery Angelique M. L., Butter Loes M., Larsen Per W. B., de Boer Onno J., Leemans Jaklien C., Florquin Sandrine, Roelofs Joris J. T. H. Author Correction: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain (Scientific Reports, (2018), 8, 1, (5542), 10.1038/s41598-018-23839-9) Scientific reports 2019;9 (1):3425 [PubMed]
  • Yang Jack, Ramirez Moral Ivan, van 't Veer Cornelis, de Vos Alex F., de Beer Regina, Roelofs Joris J. T. H., Morgan B. Paul, van der Poll Tom Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model Respiratory research 2019;20 (1):165 [PubMed]
  • Wijmans Lizzy, Bonta Peter I., Rocha-Pinto Rita, de Bruin Daniel M., Brinkman Paul, Jonkers René E., Roelofs Joris J. T. H., Poletti Venerino, Hetzel J. rgen, Annema Jouke T. Confocal Laser Endomicroscopy as a Guidance Tool for Transbronchial Lung Cryobiopsies in Interstitial Lung Disorder Respiration; international review of thoracic diseases 2019;97 (3):259-263 [PubMed]
  • Hermsen Meyke, de Bel Thomas, den Boer Marjolijn, Steenbergen Eric J., Kers Jesper, Florquin Sandrine, Roelofs Joris J. T. H., Stegall Mark D., Alexander Mariam P., Smith Byron H., Smeets Bart, Hilbrands Luuk B., van der Laak Jeroen A. W. M. Deep Learning-Based Histopathologic Assessment of Kidney Tissue Clinical journal of the American Society of Nephrology 2019;30 (10):1968-1979 [PubMed]
  • van Oort Pouline M., Brinkman Paul, Slingers Gitte, Koppen Gudrun, Maas Adrie, Roelofs Joris J., Schnabel Ronny, Bergmans Dennis C., Raes M., Goodacre Royston, Fowler Stephen J., Schultz Marcus J., Bos Lieuwe D. Exhaled breath metabolomics reveals a pathogen-specific response in a rat pneumonia model for two human pathogenic bacteria: a proof-of-concept study American journal of physiology. Lung cellular and molecular physiology 2019;316 (5):L751-L756 [PubMed]
  • Jansen Marcel. P. B., Huisman Andras, Claessen Nike, Florquin Sandrine, Roelofs Joris J. T. H. Experimental thrombocytopenia does not affect acute kidney injury 24 hours after renal ischemia reperfusion in mice Platelets 2019 [PubMed]
  • Bouatou Yassine R. Improving the contribution of histopathology in kidney diseases: From diagnosis to prognosis 2019. 169p. ISBN 9789463753562. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisors: Roelofs J. J. T. H. , Kers J.)
  • Yang Jack, van 't Veer Cornelis, Roelofs Joris J. T. H., van Heijst Jeroen W. J., de Vos Alex F., McCrae Keith R., Revenko Alexey S., Crosby Jeff, van der Poll Tom Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model American journal of physiology. Lung cellular and molecular physiology 2019;316 (1):L187-L196 [PubMed]
  • Birnie Emma, Savelkoel Jelmer, Reubsaet F., Roelofs Joris J. T. H., Soetekouw R., Kolkman Saskia, Cremers Anne Lia, Grobusch Martin P., Notermans Daan W., Wiersinga W. Joost, Rozemeijer Wouter, Rijkeboer Annemieke, Scholing Maarten, van Dijk K., Mascini Ellen M., van der Veen Henk, van den Bijllaardt Wouter, de Vries Maaike, Smeets Leonard C., Ott Alewijn, van Krimpen Kees, Herpers Bjorn L., Watttel-Louis G. Hanke, Waar Karola, Schwandt Noortje L. Q., Maat Ianthe, Dofferhoff Anthonius S. M., Vermeulen Joost N., van Westreenen Mireille, de Man P., Hofland Regina W., van Gorp J., Thijsen Steven, van der Velden Lieven B., Verduin Cornelis M. Melioidosis in travelers: An analysis of Dutch melioidosis registry data 1985–2018 Travel medicine and infectious disease 2019;32 [PubMed]
  • Jansen Marcel P. B., Roelofs Joris J. T. H., Leemans Jaklien C. Mitochondrial DNA: Innocent in Plasma, but Guilty in Urine? Shock (Augusta, Ga.) 2019;51 (2):267 [PubMed]
  • Scantlebery Angelique M. L., Uil Melissa, Butter Loes M., Poelman Renée, Claessen Nike, Girardin Stephen E., Florquin Sandrine, Roelofs Joris J. T. H., Leemans Jaklien C. NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin PLoS ONE 2019;14 (3) [PubMed]
  • de Porto Alexander P. N. A., Claushuis Theodora A. M., van der Donk Lieve E. H., de Beer Regina, de Boer Onno J., Florquin Sandrine, Roelofs Joris J. T. H., Hendriks Rudi W., van der Poll Tom, van't Veer Cornelis, de Vos Alex F. Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis Thrombosis and haemostasis 2019;119 (6):930-940 [PubMed]
  • Claushuis Theodora A. M., de Vos Alex F., Roelofs Joris J. T. H., de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Platelet-Dense Granules Worsen Pre-Infection Thrombocytopenia during Gram-Negative Pneumonia-Derived Sepsis Journal of innate immunity 2019;11 (2):168-180 [PubMed]
  • de Beer Friso M, Begieneman Mark P V, Roelofs Joris J T H, Horn Janneke, Niessen Hans W M, Schultz Marcus J, Lagrand Wim K Pulmonary complement depositions in autopsy of critically ill patients have no relation with ARDS Intensive Care Medicine Experimental 2019;7 (Suppl 1):35 [PubMed]
  • Birnie Emma, Weehuizen Tassili A. F., Lankelma Jacqueline M., de Jong Hanna K., Koh Gavin C. K. W., van Lieshout Miriam H. P., Roelofs Joris J. T. H., Budding Andries E., de Vos Alex F., van der Poll Tom, Wiersinga W. Joost Role of Toll-Like Receptor 5 (TLR5) in Experimental Melioidosis Infection and immunity 2019;87 (8) [PubMed]
  • Coumou Jeroen, Wagemakers Alex, Narasimhan Sukanya, Schuijt Tim J., Ersoz Jasmin I., Oei Anneke, de Boer Onno J., Roelofs Joris J. T. H., Fikrig Erol, Hovius Joppe W. The role of Mannose Binding Lectin in the immune response against Borrelia burgdorferi sensu lato Scientific reports 2019;9 (1) [PubMed]
  • Birnie Emma, Claushuis Theodora A. M., Koh Gavin C. K. W., Limmathurotsakul Direk, Day Nicholas P. J., Roelofs Joris J. T. H., Ware Jerry, Hou Baidong, de Vos Alex F., van der Poll Tom, van't Veer Cornelis, Wiersinga W. Joost Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis) Journal of infectious diseases 2019;219 (4):648-659 [PubMed]
  • Kleinveld Derek J B, Wirtz Mathijs R, van den Brink Daan P, Maas M Adrie W, Roelofs Joris J T H, Goslings J Carel, Hollmann Markus W, Juffermans Nicole P Use of a high platelet-to-RBC ratio of 2:1 is more effective in correcting trauma-induced coagulopathy than a ratio of 1:1 in a rat multiple trauma transfusion model Intensive Care Medicine Experimental 2019;7 (Suppl 1):42 [PubMed]
  • Klanderman Robert B., Bosboom Joachim J., Maas Adrie A. W., Roelofs Joris J. T. H., de Korte Dirk, van Bruggen Robin, van Buul Jaap D., Zuurbier Coert J., Veelo Denise P., Hollmann Markus W., Vroom Margreeth B., Juffermans Nicole P., Geerts Bart F., Vlaar Alexander P. J. Volume incompliance and transfusion are essential for transfusion-associated circulatory overload: a novel animal model Transfusion 2019;59 (12):3617-3627 [PubMed]
  • Wirtz Mathijs R., Jurgens Jordy, Zuurbier Coert J., Roelofs Joris J. T. H., Spinella Philip C., Muszynski Jennifer A., Carel Goslings J., Juffermans Nicole P. Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion Transfusion 2019;59 (1):134-145 [PubMed]
  • Scantlebery Angelique M. L., Ochodnicky Peter, Kors Lotte, Rampanelli Elena, Butter Loes M., el Boumashouli Chaima, Claessen Nike, Teske Gwen J., van den Bergh Weerman Marius A., Leemans Jaklien C., Roelofs Joris J. T. H., Florquin Sandrine β-Cyclodextrin counteracts obesity in Western diet-fed mice but elicits a nephrotoxic effect Scientific reports 2019;9 (1) [PubMed]

2018

  • Bouatou Yassine, Stokman Geurt, Claessen Nike, Roelofs Joris J. T. H., Bemelman Frédérike, Kers Jesper, Florquin Sandrine Aryl hydrocarbon receptor expression by macrophages and lymphocytes within infiltrates in BK polyomavirus associated nephropathy Transplant immunology 2018;47:18-21 [PubMed]
  • Uil Melissa, Scantlebery Angelique M. L., Butter Loes M., Larsen Per W. B., de Boer Onno J., Leemans Jaklien C., Florquin Sandrine, Roelofs Joris J. T. H. Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the 'resistant' C57Bl/6J mouse strain Scientific reports 2018;8 (1) [PubMed]
  • Bouatou Yassine, Kers Jesper, Chevalier-Florquin Marie S. N., Claessen Nike, Nguyen Tri Q., Damman Jeffrey, Proenca Henrique, Roelofs Joris J. T. H., Florquin Sandrine Diagnostic accuracy of immunofluorescence versus immunoperoxidase staining to distinguish immune complex-mediated glomerulonephritis and C3 dominant glomerulopathy Histopathology 2018;72 (4):601-608 [PubMed]
  • Westendorp B. Florien, Büller Nikè V. J. A., Karpus Olga N., van Dop Willemijn A., Koster Jan, Versteeg Rogier, Koelink Pim J., Snel Clinton Y., Meisner Sander, Roelofs Joris J. T. H., Uhmann Anja, Ver Loren van Themaat Emiel, Heijmans Jarom, Hahn Heidi, Muncan Vanesa, Wildenberg Manon E., van den Brink Gijs R. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response Cellular and molecular gastroenterology and hepatology 2018;5 (1):67-82.e1 [PubMed]
  • Stroo Ingrid, Ding Chao, Novak Andreja, Yang Jack, Roelofs Joris J. T. H., Meijers Joost C. M., Revenko Alexey S., van ’t Veer Cornelis, Zeerleder Sacha, Crosby Jeff R., van der Poll Tom Inhibition of the extrinsic or intrinsic coagulation pathway during pneumonia-derived sepsis American journal of physiology. Lung cellular and molecular physiology 2018;315 (5):L799-L809 [PubMed]
  • Qing Xiaoping, Chinenov Yurii, Redecha Patricia, Madaio Michael, Roelofs Joris J. T. H., Farber Gregory, Issuree Priya D., Donlin Laura, Mcllwain David R., Mak Tak W., Blobel Carl P., Salmon Jane E. iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling Journal of clinical investigation 2018;128 (4):1397-1412 [PubMed]
  • Ding Chao, van 't Veer Cornelis, Roelofs Joris J. T. H., Shukla Meenal, McCrae Keith R., Revenko Alexey S., Crosby Jeff, van der Poll Tom Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis American journal of physiology. Lung cellular and molecular physiology 2018;314 (3):L397-L405 [PubMed]
  • Jansen Marcel P. B., Pulskens Wilco P., Butter Loes M., Florquin Sandrine, Juffermans Nicole P., Roelofs Joris J. T. H., Leemans Jaklien C. Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction Shock (Augusta, Ga.) 2018;49 (3):301-310 [PubMed]
  • Mason Lauren M. K., Coumou Jeroen, Ersöz Jasmin I., Oei Anneke, Roelofs Joris J. T. H., Vogl Thomas, van der Poll Tom, Hovius Joppe W. R. MRP8/14 does not contribute to dissemination or inflammation in a murine model of Lyme borreliosis Immunobiology 2018;223 (11):694-698 [PubMed]
  • Claushuis Theodora A. M., de Stoppelaar Sacha F., de Vos Alex F., Grootemaat Anita E., van der Wel Nicole N., Roelofs Joris J. T. H., Ware Jerry, van't Veer Cornelis, van der Poll Tom Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis Arteriosclerosis, thrombosis, and vascular biology 2018;38 (8):1772-1784 [PubMed]
  • Claushuis Theodora A. M., de Vos Alex F., Nieswandt Bernard, Boon Louis, Roelofs Joris J. T. H., de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria Blood 2018;131 (8):864-876 [PubMed]
  • van den Boogaard Florry E., Brands Xanthe, Duitman JanWillem, de Stoppelaar Sacha F., Borensztajn Keren S., Roelofs Joris J. T. H., Hollenberg Morley D., Spek C. Arnold, Schultz Marcus J., van ‘t Veer Cornelis, van der Poll Tom Protease-activated receptor 2 facilitates bacterial dissemination in pneumococcal pneumonia Journal of infectious diseases 2018;217 (9):1462-1471 [PubMed]
  • Claushuis Theodora A. M., van der Donk Lieve E. H., Luitse Anna L., van Veen Henk A., van der Wel Nicole N., van Vught Lonneke A., Roelofs Joris J. T. H., de Boer Onno J., Lankelma Jacqueline M., Boon Louis, de Vos Alex F., van't Veer Cornelis, van der Poll Tom Role of peptidylarginine deiminase 4 in neutrophil extracellular trap formation and host defense during klebsiella pneumoniae-induced pneumonia-derived sepsis Journal of immunology (Baltimore, Md. 2018;201 (4):1241-1252 [PubMed]
  • Jansen Marcel P. B., Florquin Sandrine, Roelofs Joris J. T. H. The role of platelets in acute kidney injury Nature reviews. Nephrology 2018;14 (7):457-471 [PubMed]
  • Jansen Marcel P. B. The role of platelets in acute kidney injury 2018. 203p. ISBN 9789463801454. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Roelofs J. J. T. H.)

2017

  • Stroo Ingrid, Zeerleder Sacha, Ding Chao, Luken Brenda M., Roelofs Joris J. T. H., de Boer Onno J., Meijers Joost C. M., Castellino Francis J., van 't Veer Cornelis, van der Poll Tom Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation Thrombosis and haemostasis 2017;117 (8):1601-1614 [PubMed]
  • Gorter Ramon R., Wassenaar Emma C. E., de Boer Onno J., Bakx Roel, Roelofs Joris J. T. H., Bunders Madeleine J., van Heurn L. W. Ernst, Heij Hugo A. Composition of the cellular infiltrate in patients with simple and complex appendicitis Journal of surgical research 2017;214:190-196 [PubMed]
  • Weehuizen Tassili A. F., Birnie Emma, Ferwerda Bart, Roelofs Joris J. T. H., de Vos Alex F., Grobusch Martin P., Wiersinga W. Joost Differences in Inflammation Patterns Induced by African and Asian Burkholderia pseudomallei Isolates in Mice American journal of tropical medicine and hygiene 2017;96 (6):1365-1369 [PubMed]
  • Straat Marleen, Tuip Anita, Klei Thomas R. L., Beuger Boukje M., Roelofs Joris J. T. H., van Bruggen Robin, Juffermans Nicole P. ENDOTOXEMIA RESULTS IN TRAPPING OF TRANSFUSED RED BLOOD CELLS IN LUNGS WITH ASSOCIATED LUNG INJURY Shock (Augusta, Ga.) 2017;48 (4):484-489 [PubMed]
  • Stroo Ingrid, Yang Jack, de Boer Johannes Daan, Roelofs Joris J. T. H., van 't Veer Cornelis, Castellino Francis J., Zeerleder Sacha, van der Poll Tom Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII American journal of physiology. Lung cellular and molecular physiology 2017;312 (2):L163-L171 [PubMed]
  • Anas A. A., Yang J., Daan de Boer J., Roelofs J. J. T. H., Hou B., de Vos A. F., van der Poll T. General, but not myeloid or type II lung epithelial cell, myeloid differentiation factor 88 deficiency abrogates house dust mite induced allergic lung inflammation Clinical and experimental immunology 2017;187 (2):204-212 [PubMed]
  • Stroo Ingrid, Yang Jack, Anas Adam A., de Boer J. Daan, van Mierlo Gerard, Roem Dorina, Wouters Diana, Engel Ruchira, Roelofs Joris J. T. H., van 't Veer Cornelis, van der Poll Tom, Zeerleder Sacha Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice PLoS ONE 2017;12 (10):e0186652 [PubMed]
  • Helmerhorst Hendrik J. F., Schouten Laura R. A., Wagenaar Gerry T. M., Juffermans Nicole P., Roelofs Joris J. T. H., Schultz Marcus J., de Jonge Evert, van Westerloo David J. Hyperoxia provokes a time- and dose-dependent inflammatory response in mechanically ventilated mice, irrespective of tidal volumes Intensive Care Medicine Experimental 2017;5 (1):27 [PubMed]
  • Ochodnicky Peter, Lattenist Lionel, Ahdi Mohamed, Kers Jesper, Uil Melissa, Claessen Nike, Leemans Jaklien C., Florquin Sandrine, Meijers Joost C. M., Gerdes Victor E. A., Roelofs Joris J. T. H. Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy American journal of pathology 2017;187 (9):1971-1983 [PubMed]
  • van den Boogaard Florry E., Hofstra Jorrit J., Brands Xanthe, Levi Marcel M., Roelofs Joris J. T. H., Zaat Sebastiaan A. J., van't Veer Cornelis, van der Poll Tom, Schultz Marcus J. Nebulized Recombinant Human Tissue Factor Pathway Inhibitor Attenuates Coagulation and Exerts Modest Anti-inflammatory Effects in Rat Models of Lung Injury Journal of aerosol medicine and pulmonary drug delivery 2017;30 (2):91-99 [PubMed]
  • d'Hooghe Julia N. S., Goorsenberg Annika W. M., de Bruin Daniel M., Roelofs Joris J. T. H., Annema Jouke T., Bonta Peter I. Optical coherence tomography for identification and quantification of human airway wall layers PLoS ONE 2017;12 (10):e0184145 [PubMed]
  • Lin Cong, Majoor Christof J., Roelofs Joris J. T. H., de Kruif Martijn D., Horlings Hugo M., Borensztajn Keren, Spek C. Arnold Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer BMC cancer 2017;17 (1):113 [PubMed]
  • Lankelma Jacqueline M., Wagemakers Alex, Birnie Emma, Haak Bastiaan W., Trentelman Jos J. A., Weehuizen Tassili A. F., Ersöz Jasmin, Roelofs Joris J. T. H., Hovius Joppe W., Wiersinga W. Joost, Bins Adriaan D. Rapid DNA vaccination against Burkholderia pseudomallei flagellin by tattoo or intranasal application Virulence 2017;8 (8):1683-1694 [PubMed]
  • Jansen Marcel P. B., Emal Diba, Teske Gwendoline J. D., Dessing Mark C., Florquin Sandrine, Roelofs Joris J. T. H. Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps Kidney international 2017;91 (2):352-364 [PubMed]
  • Lankelma Jacqueline M., Birnie Emma, Weehuizen Tassili A. F., Scicluna Brendon P., Belzer Clara, Houtkooper Riekelt H., Roelofs Joris J. T. H., de Vos Alex F., van der Poll Tom, Budding Andries E., Wiersinga W. Joost The gut microbiota as a modulator of innate immunity during melioidosis PLoS neglected tropical diseases 2017;11 (4):e0005548 [PubMed]
  • Claushuis T. A. M., de Stoppelaar S. F., Stroo I., Roelofs J. J. T. H., Ottenhoff R., van der Poll T., van't Veer C. Thrombin contributes to protective immunity in pneumonia-derived sepsis via fibrin polymerization and platelet-neutrophil interactions Journal of thrombosis and haemostasis 2017;15 (4):744-757 [PubMed]

2016

  • Lattenist Lionel, Jansen Marcel P. B., Teske Gwendoline, Claessen Nike, Meijers Joost C. M., Rezaie Alireza R., Esmon Charles T., Florquin Sandrine, Roelofs Joris J. T. H. Activated protein C protects against renal ischaemia/reperfusion injury, independent of its anticoagulant properties Thrombosis and haemostasis 2016;116 (1):124-133 [PubMed]
  • Schouten Laura R. A., Helmerhorst Hendrik J. F., Wagenaar Gerry T. M., Haltenhof Tom, Lutter René, Roelofs Joris J. T. H., van Woensel Job B. M., van Kaam Anton H. L. C., Bos Albert P., Schultz Marcus J., Walther Thomas, Wösten-van Asperen Roelie M. Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats Critical care medicine 2016;44 (12):e1226-e1235 [PubMed]
  • Hoekman Daniël R., Roelofs Joris J. T. H., van Schuppen Joost, Schonenberg-Meinema Dieneke, D'Haens Geert R., Benninga Marc A. Case report of cheilitis granulomatosa and joint complaints as presentation of Crohn's disease Clinical journal of gastroenterology 2016;9 (2):73-78 [PubMed]
  • van den Boogaard Florry E., van Gisbergen Klaas P. J. M., Vernooy Juanita H., Medema Jan P., Roelofs Joris J. T. H., van Zoelen Marieke A. D., Endeman Henrik, Biesma Douwe H., Boon Louis, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Granzyme A impairs host defense during Streptococcus pneumoniae pneumonia American journal of physiology. Lung cellular and molecular physiology 2016;311 (2):L507-L516 [PubMed]
  • Yapici Ünsal, Kers Jesper, Slavujevic-Letic Ivana, Stokman Geurt, Roelofs Joris J. T. H., van Aalderen Michiel C., Groothoff Jaap W., de Boer Onno J., van der Pant Karlijn A. M. I., Claessen Nike, Hilbrands Luuk B., Bemelman Frederike J., ten Berge Ineke J. M., Florquin Sandrine Intragraft Blood Dendritic Cell Antigen-1-Positive Myeloid Dendritic Cells Increase during BK Polyomavirus-Associated Nephropathy Journal of the American Society of Nephrology 2016;27 (8):2502-2510 [PubMed]
  • Heinsbroek S. E. M., Squadrito M. L., Schilderink R., Hilbers F. W., Verseijden C., Hofmann M., Helmke A., Boon L., Wildenberg M. E., Roelofs J. J. T. H., Ponsioen C. Y., Peters C. P., te Velde A. A., Gordon S., de Palma M., de Jonge W. J. miR-511-3p, embedded in the macrophage mannose receptor gene, contributes to intestinal inflammation Mucosal immunology 2016;9 (4):960-973 [PubMed]
  • de Beer Friso, Lagrand Wim, Glas Gerie J., Beurskens Charlotte J. P., van Mierlo Gerard, Wouters Diana, Zeerleder Sacha, Roelofs Joris J. T. H., Juffermans Nicole P., Horn Janneke, Schultz Marcus J. Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia Cell biochemistry and biophysics 2016;74 (4):545-552 [PubMed]
  • Lattenist L., Ochodnický P., Ahdi M., Claessen N., Leemans J. C., Satchell S. C., Florquin S., Gerdes V. E., Roelofs J. J. T. H. Renal endothelial protein C receptor expression and shedding during diabetic nephropathy Journal of thrombosis and haemostasis 2016;14 (6):1171-1182 [PubMed]
  • Schuijt Tim J., Lankelma Jacqueline M., Scicluna Brendon P., de Sousa E Melo Felipe, Roelofs Joris J. T. H., de Boer J. Daan, Hoogendijk Arjan J., de Beer Regina, de Vos Alex, Belzer Clara, de Vos Willem M., van der Poll Tom, Wiersinga W. Joost The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia Gut 2016;65 (4):575-583 [PubMed]
  • Lattenist Lionel The Protein C system in renal disease 2016. 213p. ISBN 9789491602627. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Roelofs J. J. T. H.)
  • Weehuizen Tassili A. F., Lankelma Jacqueline M., de Jong Hanna K., de Boer Onno J., Roelofs Joris J. T. H., Day Nicholas P., Gram Hermann, de Vos Alex F., Wiersinga W. Joost Therapeutic Administration of a Monoclonal Anti-Il-1β Antibody Protects Against Experimental Melioidosis Shock (Augusta, Ga.) 2016;46 (5):566-574 [PubMed]
  • Weehuizen Tassili A. F., Hommes Tijmen J., Lankelma Jacqueline M., de Jong Hanna K., Roelofs Joris J. T. H., de Vos Alex F., Colonna Marco, van der Poll Tom, Wiersinga W. Joost Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis PLoS neglected tropical diseases 2016;10 (6):e0004747 [PubMed]
  • Hoelbeek Joris, Duivenvoorden Raphaël, de Boer Onno J., Claessen Nike, van den Bergh Weerman Marius A., Roelofs Joris J. T. H., Kers Jesper, ten Berge Ineke J. M., Florquin Sandrine Unique Renal Manifestation of Type I Cryoglobulinemia, With Massive Crystalloid Deposits in Glomerular Histiocytes, Podocytes, and Endothelial Cells American journal of clinical pathology 2016;145 (2):282-285 [PubMed]

2015

  • Kurakula K., Vos M., Logiantara A., Roelofs J. J. T. H., Nieuwenhuis M. A., Koppelman G. H., Postma D. S., Brandsma C. A., Sin D. D., Bossé Y., Nickle D. C., van Rijt L. S., de Vries C. J. M. Deficiency of FHL2 attenuates airway inflammation in mice and genetic variation associates with human bronchial hyper-responsiveness Allergy 2015;70 (12):1531-1544 [PubMed]
  • Oosterveld Michiel J. S., Garrelfs Mark R., Hoppe Bernd, Florquin Sandrine, Roelofs Joris J. T. H., van den Heuvel L. P., Amann Kerstin, Davin Jean-Claude, Bouts Antonia H. M., Schriemer Pietrik J., Groothoff Jaap W. Eculizumab in Pediatric Dense Deposit Disease Clinical journal of the American Society of Nephrology 2015;10 (10):1773-1782 [PubMed]
  • de Boer Johannes D., Berkhout Lea C., de Stoppelaar Sacha F., Yang Jack, Ottenhoff Roelof, Meijers Joost C. M., Roelofs Joris J. T. H., van't Veer Cornelis, van der Poll Tom Effect of the oral thrombin inhibitor dabigatran on allergic lung inflammation induced by repeated house dust mite administration in mice American journal of physiology. Lung cellular and molecular physiology 2015;309 (8):L768-L775 [PubMed]
  • van den Boogaard Florry E., van 't Veer Cornelis, Roelofs Joris J. T. H., Meijers Joost C. M., Schultz Marcus J., Broze George J., van der Poll Tom Endogenous tissue factor pathway inhibitor has a limited effect on host defence in murine pneumococcal pneumonia Thrombosis and haemostasis 2015;114 (1):115-122 [PubMed]
  • de Jong Hanna K., Achouiti Ahmed, Koh Gavin C. K. W., Parry Christopher M., Baker Stephen, Faiz Mohammed Abul, van Dissel Jaap T., Vollaard Albert M., van Leeuwen Ester M. M., Roelofs Joris J. T. H., de Vos Alex F., Roth Johannes, van der Poll Tom, Vogl Thomas, Wiersinga Willem Joost Expression and function of S100A8/A9 (calprotectin) in human typhoid fever and the murine Salmonella model PLoS neglected tropical diseases 2015;9 (4):e0003663 [PubMed]
  • van den Boogaard Florry E., Hofstra Jorrit J., van 't Veer Cornelis, Levi Marcel M., Roelofs Joris J. T. H., van der Poll Tom, Schultz Marcus J. Feasibility and Safety of Local Treatment with Recombinant Human Tissue Factor Pathway Inhibitor in a Rat Model of Streptococcus pneumoniae Pneumonia PLoS ONE 2015;10 (5):e0127261 [PubMed]
  • Kurakula Kondababu, Vos Mariska, Logiantara Adrian, Roelofs Joris J., Nieuwenhuis Maartje A., Koppelman Gerard H., Postma Dirkje S., van Rijt Leonie S., de Vries Carlie J. M. Nuclear Receptor Nur77 Attenuates Airway Inflammation in Mice by Suppressing NF-κB Activity in Lung Epithelial Cells Journal of immunology (Baltimore, Md. 2015;195 (4):1388-1398 [PubMed]
  • de Stoppelaar S. F., van't Veer C., Roelofs J. J. T. H., Claushuis T. A. M., de Boer O. J., Tanck M. W. T., Hoogendijk A. J., van der Poll T. Platelet and endothelial cell P-selectin are required for host defense against Klebsiella pneumoniae-induced pneumosepsis Journal of thrombosis and haemostasis 2015;13 (6):1128-1138 [PubMed]
  • Lattenist Lionel, Teske Gwendoline, Claessen Nike, Florquin Sandrine, Conway Edward M., Roelofs Joris J. T. H. The lectin like domain of thrombomodulin is involved in the defence against pyelonephritis Thrombosis research 2015;136 (6):1325-1331 [PubMed]
  • Sentís Alexis, Kers Jesper, Yapici Unsal, Claessen Nike, Roelofs Joris J. T. H., Bemelman Frederike J., ten Berge Ineke J. M., Florquin Sandrine The prognostic significance of glomerular infiltrating leukocytes during acute renal allograft rejection Transplant immunology 2015;33 (3):168-175 [PubMed]
  • de Stoppelaar S. F., Claushuis T. A. M., Jansen M. P. B., Hou B., Roelofs J. J. T. H., van 't Veer C., van der Poll T. The role of platelet MyD88 in host response during gram-negative sepsis Journal of thrombosis and haemostasis 2015;13 (9):1709-1720 [PubMed]
  • Tudpor Kukiat, van der Eerden Bram C. J., Jongwattanapisan Prapaporn, Roelofs Joris J. T. H., van Leeuwen Johannes P. T. M., Bindels René J. M., Hoenderop Joost G. J. Thrombin receptor deficiency leads to a high bone mass phenotype by decreasing the RANKL/OPG ratio Bone 2015;72:14-22 [PubMed]
  • van den Boogaard Florry E., Schouten Marcel, de Stoppelaar Sacha F., Roelofs Joris J. T. H., Brands Xanthe, Schultz Marcus J., van't Veer Cornelis, van der Poll Tom Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia Critical care medicine 2015;43 (3):e75-e83 [PubMed]

2014

  • Ziech Manon L. W., Hummel Thalia Z., Smets Anne M. J. B., Nievelstein Rutger A. J., Lavini Cristina, Caan Matthan W. A., Nederveen Aart J., Roelofs Joris J. T. H., Bipat Shandra, Benninga Marc A., Kindermann Angelika, Stoker Jaap Accuracy of abdominal ultrasound and MRI for detection of Crohn disease and ulcerative colitis in children Pediatric radiology 2014;44 (11):1370-1378 [PubMed]
  • Goeijenbier Marco, van Gorp Eric C. M., van den Brand Judith M. A., Stittelaar Koert, Bakhtiari Kamran, Roelofs Joris J. T. H., van Amerongen Geert, Kuiken Thijs, Martina Byron E. E., Meijers Joost C. M., Osterhaus Albert D. M. E. Activation of coagulation and tissue fibrin deposition in experimental influenza in ferrets BMC microbiology 2014;14 (1):134 [PubMed]
  • Kager Liesbeth M., Runge Jurgen H., Nederveen Aart J., Roelofs Joris J. T. H., Stoker Jaap, Maas Mario, van der Poll Tom A new murine model to study musculoskeletal tuberculosis (short communication) Tuberculosis (Edinburgh, Scotland) 2014;94 (3):306-310 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., de Boer Onno J., Weiler Hartmut, van 't Veer Cornelis, van der Poll Tom A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis) PLoS neglected tropical diseases 2014;8 (4):e2819 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., van 't Veer Cornelis, van der Poll Tom Deficiency of protease-activated receptor-1 limits bacterial dissemination during severe Gram-negative sepsis (melioidosis) Microbes and infection / Institut Pasteur 2014;16 (2):171-174 [PubMed]
  • Vergouwen M. D. I., Knaup V. L., Roelofs J. J. T. H., de Boer O. J., Meijers J. C. M. Effect of recombinant ADAMTS-13 on microthrombosis and brain injury after experimental subarachnoid hemorrhage Journal of thrombosis and haemostasis 2014;12 (6):943-947 [PubMed]
  • Tielbeek Jeroen A. W., Ziech Manon L. W., Li Zhang, Lavini Cristina, Bipat Shandra, Bemelman Willem A., Roelofs Joris J. T. H., Ponsioen Cyriel Y., Vos Frans M., Stoker Jaap Evaluation of conventional, dynamic contrast enhanced and diffusion weighted MRI for quantitative Crohn's disease assessment with histopathology of surgical specimens European radiology 2014;24 (3):619-629 [PubMed]
  • van Montfoort Maurits L., Kuijpers Marijke J. E., Knaup Véronique L., Bhanot Sanjay, Monia Brett P., Roelofs Joris J. T. H., Heemskerk Johan W. M., Meijers Joost C. M. Factor XI regulates pathological thrombus formation on acutely ruptured atherosclerotic plaques Arteriosclerosis, thrombosis, and vascular biology 2014;34 (8):1668-1673 [PubMed]
  • de Jong Hanna K., Koh Gavin C. K. W., van Lieshout Miriam H. P., Roelofs Joris J. T. H., van Dissel Jaap T., van der Poll Tom, Wiersinga W. Joost Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection BMC immunology 2014;15 (1):30 [PubMed]
  • de Boer J. Daan, Yang Jack, van den Boogaard Florry E., Hoogendijk Arie J., de Beer Regina, van der Zee Jaring S., Roelofs Joris J. T. H., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Mast cell-deficient kit mice develop house dust mite-induced lung inflammation despite impaired eosinophil recruitment Journal of innate immunity 2014;6 (2):219-226 [PubMed]
  • van den Boogaard Florry E., Brands Xanthe, Roelofs Joris J. T. H., de Beer Regina, de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Mast cells impair host defense during murine Streptococcus pneumoniae pneumonia Journal of infectious diseases 2014;210 (9):1376-1384 [PubMed]
  • Beurskens Charlotte J., Aslami Hamid, de Beer Friso M., Roelofs Joris J. T. H., Vroom Margreeth B., Juffermans Nicole P. Mechanical ventilation with heliox in an animal model of acute respiratory distress syndrome Intensive Care Medicine Experimental 2014;2 (1):13 [PubMed]
  • Müller Marcella C. A., Tuinman Pieter R., van der Sluijs Koenraad F., Boon Louis, Roelofs Joris J., Vroom Margreeth B., Juffermans Nicole P. Methylprednisolone fails to attenuate lung injury in a mouse model of transfusion related acute lung injury Transfusion 2014;54 (4):996-1001 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., Stroo Ingrid, Achouiti Ahmed, van 't Veer Cornelis, Conway Edward M., van der Poll Tom Mice Lacking the Lectin-Like Domain of Thrombomodulin Are Protected Against Melioidosis Critical care medicine 2014;42 (3):E221-E230 [PubMed]
  • de Jong Hanna K., Koh Gavin C. K. W., Achouiti Ahmed, van der Meer Anne J., Bulder Ingrid, Stephan Femke, Roelofs Joris J. T. H., Day Nick P. J., Peacock Sharon J., Zeerleder Sacha, Wiersinga W. Joost Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis) Intensive Care Medicine Experimental 2014;2 (1):21 [PubMed]
  • Heijmans Jarom, Wielenga Mattheus C. B., Rosekrans Sanne Liesbeth, van Lidth de Jeude Jooske F., Roelofs Joris, Groothuis Patrick, Ederveen Antwan, de Jonge-Muller Eveline S. M., Biemond Izak, Hardwick James C. H., D'Haens Geert, Hommes Daniel W., Muncan Vanesa, van den Brink Gijs R. Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer Gut 2014;63 (2):310-316 [PubMed]
  • de Boer Johannes Daan, Kager Liesbeth M., Roelofs Joris J. T. H., Meijers Joost C. M., de Boer Onno J., Weiler Hartmut, Isermann Berend, van 't Veer Cornelis, van der Poll Tom Overexpression of activated protein C hampers bacterial dissemination during pneumococcal pneumonia BMC infectious diseases 2014;14 (1):559 [PubMed]
  • de Beer F. M., Aslami H., Hoeksma J., van Mierlo G., Wouters D., Zeerleder S., Roelofs J. J. T. H., Juffermans N. P., Schultz M. J., Lagrand W. K. Plasma-derived human C1-esterase inhibitor does not prevent mechanical ventilation-induced pulmonary complement activation in a rat model of Streptococcus pneumoniae pneumonia Cell biochemistry and biophysics 2014;70 (2):795-803 [PubMed]
  • de Boer J. Daan, van't Veer Cornelis, Stroo Ingrid, van der Meer Anne J., de Vos Alex F., van der Zee Jaring S., Roelofs Joris J. T. H., van der Poll Tom Protease-activated receptor-2 deficient mice have reduced house dust mite-evoked allergic lung inflammation Innate immunity 2014;20 (6):618-625 [PubMed]
  • Shi Kun, Queiroz Karla C. S., Roelofs Joris J. T. H., van Noesel Carel J. M., Richel Dirk J., Spek C. Arnold Protease-activated receptor 2 suppresses lymphangiogenesis and subsequent lymph node metastasis in a murine pancreatic cancer model Journal of pathology 2014;234 (3):398-409 [PubMed]
  • Müller M. C. A., Stroo I., Wouters D., Zeerleder S. S., Roelofs J. J. T. H., Boon L., Vroom M. B., Juffermans N. P. The effect of C1-inhibitor in a murine model of transfusion-related acute lung injury Vox sanguinis 2014;107 (1):71-75 [PubMed]
  • Schouten Marcel, de Boer J. Daan, Kager Liesbeth M., Roelofs Joris J. T. H., Meijers Joost C. M., Esmon Charles T., Levi Marcel, van 't Veer Cornelis, van der Poll Tom The endothelial protein C receptor impairs the antibacterial response in murine pneumococcal pneumonia and sepsis Thrombosis and haemostasis 2014;111 (5):970-980 [PubMed]
  • Kuipers Maria T., Aslami Hamid, Tuinman Pieter Roel, Tuip-de Boer Anita M., Jongsma Geartsje, van der Sluijs Koenraad F., Choi Goda, Wolthuis Esther K., Roelofs Joris J. T. H., Bresser Paul, Schultz Marcus J., van der Poll Tom, Wieland Catharina W. The receptor for advanced glycation end products in ventilator-induced lung injury Intensive Care Medicine Experimental 2014;2 (1):22 [PubMed]
  • Kager Liesbeth M., de Vos Alex F., Roelofs Joris J. T. H., van der Loos Chris M., de Boer Onno J., van't Veer Cornelis, Conway Edward M., van der Poll Tom The thrombomodulin lectin-like domain does not change host responses to tuberculosis Thrombosis and haemostasis 2014;111 (2):345-353 [PubMed]
  • de Stoppelaar Sacha F., van 't Veer Cornelis, Claushuis Theodora A. M., Albersen Bregje J. A., Roelofs Joris J. T. H., van der Poll Tom Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice Blood 2014;124 (25):3781-3790 [PubMed]

2013

  • Aslami Hamid, Beurskens Charlotte J. P., de Beer Friso M., Kuipers Maria T., Roelofs Joris J. T. H., Hegeman Maria A., van der Sluijs Koen F., Schultz Marcus J., Juffermans Nicole P. A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion Cytokine 2013;61 (2):614-621 [PubMed]
  • van Lienden Krijn P., Hoekstra Lisette T., van Trigt Jessica D., Roelofs Joris J., van Delden Otto M., van Gulik Thomas M. Effect of hepatic artery embolization on liver hypertrophy response in a rabbit liver VX2 tumor model Hepatobiliary & pancreatic diseases international 2013;12 (6):622-629 [PubMed]
  • Kager L. M., Wiersinga W. J., Roelofs J. J., Meijers J. C. M., Zeerleder S. S., Esmon C. T., van't Veer C., van der Poll T. Endogenous protein C has a protective role during Gram-negative pneumosepsis (melioidosis) Journal of thrombosis and haemostasis 2013;11 (2):282-292 [PubMed]
  • Kager Liesbeth M., Weehuizen Tassili A., Wiersinga W. Joost, Roelofs Joris J. T. H., Meijers Joost C. M., Dondorp Arjen M., van 't Veer Cornelis, van der Poll Tom Endogenous α2-antiplasmin is protective during severe gram-negative sepsis (melioidosis) American journal of respiratory and critical care medicine 2013;188 (8):967-975 [PubMed]
  • Kuipers Maria T., Vogl Thomas, Aslami Hamid, Jongsma Geartsje, van den Berg Elske, Vlaar Alexander P. J., Roelofs Joris J. T. H., Juffermans Nicole P., Schultz Marcus J., van der Poll Tom, Roth Johannes, Wieland Catharina W. High levels of S100A8/A9 proteins aggravate ventilator-induced lung injury via TLR4 signaling PLoS ONE 2013;8 (7):e68694 [PubMed]
  • Aslami Hamid, Pulskens Wilco P., Kuipers Maria T., Bos Aafkeline P., van Kuilenburg André B. P., Wanders Ronald J. A., Roelofsen Jeroen, Roelofs Joris J. T. H., Kerindongo Raphaela P., Beurskens Charlotte J. P., Schultz Marcus J., Kulik Wim, Weber Nina C., Juffermans Nicole P. Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status PLoS ONE 2013;8 (5):e63497 [PubMed]
  • Daan de Boer J., Roelofs Joris J. T. H., de Vos Alex F., de Beer Regina, Schouten Marcel, Hommes Tijmen J., Hoogendijk Arie J., de Boer Onno J., Stroo Ingrid, van der Zee Jaring S., Veer Cornelis Van't, van der Poll Tom Lipopolysaccharide inhibits Th2 lung inflammation induced by house dust mite allergens in mice American journal of respiratory cell and molecular biology 2013;48 (3):382-389 [PubMed]
  • Hoekstra Lisette T., Bieze Matthanja, Erdogan Deha, Roelofs Joris J. T. H., Beuers Ulrich H. W., van Gulik Thomas M. Management of giant liver hemangiomas: an update Expert review of gastroenterology & hepatology 2013;7 (3):263-268 [PubMed]
  • Hofstra Jorrit J., Cornet Alexander D., Declerck Paul J., Dixon Barry, Aslami Hamid, Vlaar Alexander P. J., Roelofs Joris J., van der Poll Tom, Levi Marcel, Schultz Marcus J. Nebulized fibrinolytic agents improve pulmonary fibrinolysis but not inflammation in rat models of direct and indirect acute lung injury PLoS ONE 2013;8 (2):e55262 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., de Boer Onno J., Meijers Joost C. M., Isermann Berend, van't Veer Cornelis, van der Poll Tom Overexpression of activated protein C is detrimental during severe experimental gram-negative sepsis (melioidosis) Critical care medicine 2013;41 (10):e266-e274 [PubMed]
  • Kager Liesbeth M., Schouten Marcel, Wiersinga W. Joost, de Boer J. Daan, Lattenist Lionel C. W., Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, Dondorp Arjen M., Esmon Charles T., van 't Veer Cornelis, van der Poll Tom Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis) PLoS neglected tropical diseases 2013;7 (7):e2306 [PubMed]
  • de Stoppelaar S. F., van't Veer C., van den Boogaard F. E., Nieuwland R., Hoogendijk A. J., de Boer O. J., Roelofs J. J. T. H., van der Poll T. Protease activated receptor 4 limits bacterial growth and lung pathology during late stage Streptococcus pneumoniae induced pneumonia in mice Thrombosis and haemostasis 2013;110 (3):582-592 [PubMed]
  • Lattenist Lionel, Kers Jesper, Claessen Nike, ten Berge Ineke J. M., Bemelman Frederike J., Florquin Sandrine, Roelofs Joris J. T. H. Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection PLoS ONE 2013;8 (5):e64994 [PubMed]
  • de Stoppelaar Sacha F., Bootsma Hester J., Zomer Aldert, Roelofs Joris J. T. H., Hermans Peter W. M., van 't Veer Cornelis, van der Poll Tom Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia PLoS ONE 2013;8 (11):e80062 [PubMed]
  • Kager Liesbeth M., Roelofs Joris J. T. H., de Vos Alex F., Wieland Catharina W., Schouten Marcel, Meijers Joost C. M., Isermann Berend, van't Veer Cornelis, Esmon Charles T., van der Poll Tom The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis Thrombosis and haemostasis 2013;109 (4):726-737 [PubMed]
  • Hegeman Maria A., Hemmes Sabrine N. T., Kuipers Maria T., Bos Lieuwe D. J., Jongsma Geartsje, Roelofs Joris J. T. H., van der Sluijs Koenraad F., Juffermans Nicole P., Vroom Margreeth B., Schultz Marcus J. The Extent of Ventilator-Induced Lung Injury in Mice Partly Depends on Duration of Mechanical Ventilation Critical care research and practice 2013;2013:435236 [PubMed]
  • Schouten Marcel, de Boer J. Daan, van 't Veer Cornelis, Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, Conway Edward M., van der Poll Tom The lectin-like domain of thrombomodulin hampers host defence in pneumococcal pneumonia European respiratory journal 2013;41 (4):935-942 [PubMed]
  • Vermeij Jan-Dirk, Aslami Hamid, Fluiter Kees, Roelofs Joris J., van den Bergh Walter M., Juffermans Nicole P., Schultz Marcus J., van der Sluijs Koen, van de Beek Diederik, van Westerloo David J. Traumatic brain injury in rats induces lung injury and systemic immune suppression Journal of neurotrauma 2013;30 (24):2073-2079 [PubMed]

2012

  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, van't Veer Cornelis, van der Poll Tom Endogenous tissue-type plasminogen activator impairs host defense during severe experimental gram-negative sepsis (melioidosis) Critical care medicine 2012;40 (7):2168-2175 [PubMed]
  • Dik Kathelijne, de Bruijne Joep, Takkenberg R. Bart, Roelofs Joris J., Tempelmans Marjan J., Dijkgraaf Marcel G. W., Gelderblom Huub C., Reesink Henk W., Meijers Joost C. M., Jansen Peter L., Levi Marcel Factor XIII Val34Leu mutation accelerates the development of fibrosis in patients with chronic hepatitis B and C Hepatology research 2012;42 (7):668-676 [PubMed]
  • Dik Kathelijne, de Bruijne Joep, Takkenberg R. Bart, Roelofs Joris J., Tempelmans Marjan J., Dijkgraaf Marcel G. W., Gelderblom Huub C., Reesink Henk W., Meijers Joost C. M., Jansen Peter L., Levi Marcel Factor XIII Val34Leu mutation and liver fibrosis rate in viral hepatitis Reply Hepatology research 2012;42 (11):1154-1155 [PubMed]
  • Heinsbroek Sigrid E. M., Oei Anneke, Roelofs Joris J. T. H., Dhawan Shobhit, te Velde Anje, Gordon Siamon, de Jonge Wouter J. Genetic deletion of dectin-1 does not affect the course of murine experimental colitis BMC gastroenterology 2012;12 (1):33 [PubMed]
  • Hoekstra Lisette T., Bieze Matthanja, Erdogan Deha, Roelofs Joris J. T. H., Beuers Ulrich H. W., van Gulik Thomas M. Het reuzenhemangioom in de lever: diagnostiek en behandeling Nederlands tijdschrift voor geneeskunde 2012;156 (31):A3820 [PubMed]
  • Beurskens Charlotte J. P., Aslami Hamid, Kuipers Maria T., Horn Janneke, Vroom Margreeth B., van Kuilenburg André B. P., Roelofs Joris J. T. H., Schultz Marcus J., Juffermans Nicole P. Induced hypothermia is protective in a rat model of pneumococcal pneumonia associated with increased adenosine triphosphate availability and turnover Critical care medicine 2012;40 (3):919-926 [PubMed]
  • van den Esschert Jacomina W., van Lienden Krijn P., Alles Lindy K., van Wijk Albert C., Heger Michal, Roelofs Joris J., van Gulik Thomas M. Liver Regeneration After Portal Vein Embolization Using Absorbable and Permanent Embolization Materials in a Rabbit Model Annals of surgery 2012;255 (2):311-318 [PubMed]
  • Vlaar A. P. J., Kuipers M. T., Hofstra J. J., Wolthuis E. K., Wieland C. W., Roelofs J. J. T. H., Boon L., Schultz M. J., Lutter R., Juffermans N. P. Mechanical ventilation and the titer of antibodies as risk factors for the development of transfusion-related lung injury Critical care research and practice 2012;2012:720950 [PubMed]
  • Aslami Hamid, Kuipers Maria T., Beurskens Charlotte J. P., Roelofs Joris J. T. H., Schultz Marcus J., Juffermans Nicole P. Mild hypothermia reduces ventilator-induced lung injury, irrespective of reducing respiratory rate Translational research 2012;159 (2):110-117 [PubMed]
  • Kuipers Maria T., Aslami Hamid, Vlaar Alexander P. J., Juffermans Nicole P., Tuip-de Boer Anita M., Hegeman Maria A., Jongsma Geartsje, Roelofs Joris J. T. H., van der Poll Tom, Schultz Marcus J., Wieland Catharina W. Pre-Treatment with Allopurinol or Uricase Attenuates Barrier Dysfunction but Not Inflammation during Murine Ventilator-Induced Lung Injury PLoS ONE 2012;7 (11):e50559 [PubMed]
  • Schouten Marcel, van't Veer Cornelis, Roelofs Joris J. T. H., Levi Marcel, van der Poll Tom Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study Critical care (London, England) 2012;16 (6):R238 [PubMed]
  • Wolthuis Esther K., Vlaar Alexander P. J., Choi Goda, Roelofs Joris J. T. H., Levi Marcel, Juffermans Nicole P., Schultz Marcus J. Relative Tissue Factor Deficiency Attenuates Ventilator-Induced Coagulopathy but Does Not Protect against Ventilator-Induced Lung Injury in Mice Critical care research and practice 2012;2012:130410 [PubMed]
  • Hoogendijk Arie J., Roelofs Joris J. T. H., Duitman Janwillem, van Lieshout Miriam H. P., Blok Dana C., van der Poll Tom, Wieland Catharina W. R-roscovitine Reduces Lung Inflammation Induced by Lipoteichoic Acid and Streptococcus pneumoniae Molecular medicine (Cambridge, Mass.) 2012;18 (7):1086-1095 [PubMed]
  • van Lienden Krijn P., van den Esschert Jacomina W., Rietkerk Max, Heger Michal, Roelofs Joris J. T. H., Lameris Johan S., van Gulik Thomas M. Short-term Effects of Combined Hepatic Vein Embolization and Portal Vein Embolization for the Induction of Liver Regeneration in a Rabbit Model Journal of vascular and interventional radiology 2012;23 (7):962-967 [PubMed]
  • Yapici Ü, Roelofs J. J. T. H., Florquin S. The Importance of Testing Anti-IL-17 Antibodies From Different Suppliers American journal of transplantation 2012;12 (2):504-505 [PubMed]
  • Kwakernaak A. J., Hazenberg M. D., Roelofs J. J., van Noesel C. J., van Oers M. H., van Tellingen A. T-lymfoblastair lymfoom zich presenterend als primair renaal lymfoom met acute nierinsufficiëntie Nederlands tijdschrift voor hematologie 2012;9:34
  • Kuipers Maria T., Aslami Hamid, Janczy John R., van der Sluijs Koenraad F., Vlaar Alexander P. J., Wolthuis Esther K., Choi Goda, Roelofs Joris J. T. H., Flavell Richard A., Sutterwala Fayyaz S., Bresser Paul, Leemans Jaklien C., van der Poll Tom, Schultz Marcus J., Wieland Catharina W. Ventilator-induced Lung Injury Is Mediated by the NLRP3 Inflammasome Anesthesiology 2012;116 (5):1104-1115 [PubMed]

2011

  • de Graaf Wilmar, van den Esschert Jacomina W., van Lienden Krijn P., Roelofs Joris J. T. H., van Gulik Thomas M. A rabbit model for selective portal vein embolization Journal of surgical research 2011;171 (2):486-494 [PubMed]
  • Schuijt Tim J., Coumou Jeroen, Narasimhan Sukanya, Dai Jianfeng, Deponte Kathleen, Wouters Diana, Brouwer Mieke, Oei Anneke, Roelofs Joris J. T. H., van Dam Alje P., van der Poll Tom, van't Veer Cornelis, Hovius Joppe W., Fikrig Erol A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent Cell host & microbe 2011;10 (2):136-146 [PubMed]
  • Schouten M., van der Sluijs K. F., Roelofs J. J. T. H., Levi M., van't Veer C., van der Poll T. Factor V Leiden mutation does not affect coagulopathy or outcome in lethal H1N1 influenza (vol 36, pg 1346, 2010) European respiratory journal 2011;37 (3):726
  • Schouten Marcel, de Boer J. Daan, van der Sluijs Koenraad F., Roelofs Joris J. T. H., van't Veer Cornelis, Levi Marcel, Esmon Charles T., van der Poll Tom Impact of Endogenous Protein C on Pulmonary Coagulation and Injury during Lethal H1N1 Influenza in Mice American journal of respiratory cell and molecular biology 2011;45 (4):789-794 [PubMed]
  • Yapici Ünsal, Kers Jesper, Bemelman Fréderike J., Roelofs Joris J. T. H., Groothoff Jaap W., van der Loos Chris M., van Donselaar-van der Pant Karlijn A. M. I., Idu Mirza M., Claessen Nike, ten Berge Ineke J. M., Florquin Sandrine Interleukin-17 positive cells accumulate in renal allografts during acute rejection and are independent predictors of worse graft outcome Transplant international 2011;24 (10):1008-1017 [PubMed]
  • Cornet Alexander D., Hofstra Jorrit J., Vlaar Alexander P., van den Boogaard Floor E., Roelofs Joris J., van der Poll Tom, Levi Marcel, Groeneveld A. B. Johan, Schultz Marcus J. Nebulized anticoagulants limit coagulopathy but not inflammation in pseudomonas aeruginosa-induced pneumonia in rats Shock (Augusta, Ga.) 2011;36 (4):417-423 [PubMed]
  • Kager L. M., Wiersinga W. J., Roelofs J. J. T. H., Meijers J. C. M., Levi M. [=Marcel M.], van't Veer C., van der Poll T. Plasminogen activator inhibitor type I contributes to protective immunity during experimental Gram-negative sepsis (melioidosis) Journal of thrombosis and haemostasis 2011;9 (10):2020-2028 [PubMed]
  • Wolthuis Esther K., Vlaar Alexander P. J., Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., de Waard Vivian, Juffermans Nicole P., Schultz Marcus J. Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury Critical care research and practice 2011;2011:217896 [PubMed]
  • van den Esschert Jacomina W., van Lienden Krijn P., de Graaf Wilmar, Maas Martinus A. W., Roelofs Joris J. T. H., Heger Michal, van Gulik Thomas M. Portal vein embolization induces more liver regeneration than portal vein ligation in a standardized rabbit model Surgery 2011;149 (3):378-385 [PubMed]
  • Kwakernaak Arjan J., Hazenberg Mette D., Roelofs Joris J. T. H., van Noesel Carel J. M., van Oers Marinus H. J., van Tellingen Anne Precursor T-lymphoblastic lymphoma presenting as primary renal lymphoma with acute renal failure NDT Plus 2011;4 (5):289-291 [PubMed]
  • Schouten Marcel, van 't Veer Cornelis, Roelofs Joris J. T. H., Gerlitz Bruce, Grinnell Brian W., Levi Marcel, van der Poll Tom Recombinant activated protein C attenuates coagulopathy and inflammation when administered early in murine pneumococcal pneumonia Thrombosis and haemostasis 2011;106 (6):1189-1196 [PubMed]
  • van den Boogaard F. E., Brands X., Schultz M. J., Levi M. [=Marcel M.], Roelofs J. J. T. H., van 't Veer C., van der Poll T. Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia Journal of thrombosis and haemostasis 2011;9 (1):122-132 [PubMed]
  • Ziech Manon L. W., Bipat Shandra, Roelofs Joris J. T. H., Nio C. Yung, Mearadji Banafsche, van Doorn Sascha, Spijkerboer Anje M., Stoker Jaap Retrospective comparison of magnetic resonance imaging features and histopathology in Crohn's disease patients European journal of radiology 2011;80 (3):e299-e305 [PubMed]
  • Queiroz Karla C. S., van 't Veer Cornelis, van den Berg Yascha, Duitman Janwillem, Versteeg Henri H., Aberson Hella L., Groot Angelique P., Verstege Marleen I., Roelofs Joris J. T. H., te Velde Anje A., Spek C. Arnold Tissue factor-dependent chemokine production aggravates experimental colitis Molecular medicine (Cambridge, Mass.) 2011;17 (9-10):1119-1126 [PubMed]

2010

  • Schouten Marcel, van der Sluijs Koenraad F., Gerlitz Bruce, Grinnell Brian W., Roelofs Joris J. T. H., Levi Marcel M., van 't Veer Cornelis, van der Poll Tom Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study Critical care (London, England) 2010;14 (2):R65 [PubMed]
  • de Graaf Wilmar, van Lienden Krijn P., Dinant Sander, Roelofs Joris J. T. H., Busch Olivier R. C., Gouma Dirk J., Bennink Roelof J., van Gulik Thomas M. Assessment of Future Remnant Liver Function Using Hepatobiliary Scintigraphy in Patients Undergoing Major Liver Resection Journal of gastrointestinal surgery 2010;14 (2):369-378 [PubMed]
  • Schouten M., van der Sluijs K. F., Roelofs J. J. T. H., Levi M. [=Marcel M.], van't Veer C., van der Poll T. Factor V Leiden mutation does not affect coagulopathy or outcome in lethal H1N1 influenza European respiratory journal 2010;36 (6):1346-1354 [PubMed]
  • Schouten Marcel, van 't Veer Cornelis, Roelofs Joris Jth, Levi Marcel, van der Poll Tom Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study Critical care (London, England) 2010;14 (4):R145 [PubMed]
  • Kers Jesper, Xu-Dubois Yi-Chun, Rondeau Eric, Claessen Nike, Idu Mirza M., Roelofs Joris J. T. H., Bemelman Fréderike J., ten Berge Ineke J. M., Florquin Sandrine Intragraft Tubular Vimentin and CD44 Expression Correlate With Long-Term Renal Allograft Function and Interstitial Fibrosis and Tubular Atrophy Transplantation 2010;90 (5):502-509 [PubMed]
  • Vlaar A. P. J., Wolthuis E. K., Hofstra J. J., Roelofs J. J. T. H., Boon L., Schultz M. J., Lutter R., Juffermans N. P. Mechanical ventilation aggravates transfusion-related acute lung injury induced by MHC-I class antibodies Intensive care medicine 2010;36 (5):879-887 [PubMed]
  • Hofstra Jorrit J., Vlaar Alexander P., Cornet Alexander D., Dixon Barry, Roelofs Joris J., Choi Goda, van der Poll Tom, Levi Marcel, Schultz Marcus J. Nebulized Anticoagulants Limit Pulmonary Coagulopathy, But Not Inflammation, in a Model of Experimental Lung Injury Journal of aerosol medicine and pulmonary drug delivery 2010;23 (2):105-111 [PubMed]
  • Vlaar Alexander P. J., Hofstra Jorrit J., Kulik Wim, van Lenthe Henk, Nieuwland Rienk, Schultz Marcus J., Levi Marcel M., Roelofs Joris J. T. H., Tool Anton T. J., de Korte Dirk, Juffermans Nicole P. Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model Blood 2010;116 (8):1360-1368 [PubMed]
  • Aslami Hamid, Heinen André, Roelofs Joris J. T. H., Zuurbier Coert J., Schultz Marcus J., Juffermans Nicole P. Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury Intensive care medicine 2010;36 (11):1946-1952 [PubMed]
  • Schouten Marcel, van 't Veer Cornelis, van den Boogaard Florry E., Gerlitz Bruce, Grinnell Brian W., Roelofs Joris J. T. H., Levi Marcel, van der Poll Tom Therapeutic recombinant murine activated protein C attenuates pulmonary coagulopathy and improves survival in murine pneumococcal pneumonia Journal of infectious diseases 2010;202 (10):1600-1607 [PubMed]
  • Verkleij Chantal J. N., Roelofs Joris J. T. H., Havik Stefan R., Meijers Joost C. M., Marx Pauline F. The role of thrombin-activatable fibrinolysis inhibitor in diabetic wound healing Thrombosis research 2010;126 (5):442-446 [PubMed]
  • Wiersinga W. Joost, Kager Liesbeth M., Hovius Joppe W. R., van der Windt Gerritje J. W., de Vos Alex F., Meijers Joost C. M., Roelofs Joris J., Dondorp Arjen, Levi Marcel, Day Nicholas P., Peacock Sharon J., van der Poll Tom Urokinase Receptor Is Necessary for Bacterial Defense against Pneumonia-Derived Septic Melioidosis by Facilitating Phagocytosis Journal of immunology (Baltimore, Md. 2010;184 (6):3079-3086 [PubMed]

2009

  • Roelofs Joris J. T. H., Rouschop Kasper M. A., Teske Gwendoline J. D., Wagenaar Gerry T. M., Claessen Nike, Weening Jan J., van der Poll Tom, Florquin Sandrine Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection Nephrology, dialysis, transplantation 2009;24 (3):801-808 [PubMed]
  • Leendertse Masja, Heikens Esther, Wijnands Lucas M., van Luit-Asbroek Miranda, Teske Gwendoline J. D., Roelofs Joris J. T. H., Bonten Marc J. M., van der Poll Tom, Willems Rob J. L. Enterococcal surface protein transiently aggravates Enterococcus faecium-induced urinary tract infection in mice Journal of infectious diseases 2009;200 (7):1162-1165 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., Roelofs Joris J. T. H., Top Janetta, Bonten Marc J. M., van der Poll Tom Intestinal Colonization with Enterococcus faecium Does Not Influence Pulmonary Defense against Pseudomonas aeruginosa in Mice PLoS ONE 2009;4 (8):e6775 [PubMed]
  • Yapici Unsal, Bemelman Fréderike J., Scheepstra Cornelis G., Roelofs Joris J. T. H., Claessen Nike, van der Loos Chris, van Donselaar-van der Pant Karlijn, Bouts Antonia H. M., Idu Mirza M., Rowshani Ajda T., ten Berge Ineke J. M., Florquin Sandrine Intragraft FOXP3 Protein or mRNA During Acute Renal Allograft Rejection Correlates With Inflammation, Fibrosis, and Poor Renal Outcome Transplantation 2009;87 (9):1377-1380 [PubMed]
  • Wolthuis Esther K., Vlaar Alexander Pj, Choi Goda, Roelofs Joris J. T. H., Juffermans Nicole P., Schultz Marcus J. Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice Critical care (London, England) 2009;13 (1):R1 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., Roelofs Joris J. T. H., Bonten Marc J. M., van der Poll Tom Neutrophils Are Essential for Rapid Clearance of Enterococcus faecium in Mice Infection and immunity 2009;77 (1):485-491 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., Roelofs Joris J. T. H., van Rooijen Nico, Bonten Marc J. M., van der Poll Tom Peritoneal macrophages are important for the early containment of Enterococcus faecium peritonitis in mice Innate immunity 2009;15 (1):3-12 [PubMed]
  • Roelofs Joris J. T. H., Teske Gwendoline J. D., Bonta Peter I., de Vries Carlie J. M., Meijers Joost C. M., Weening Jan J., van der Poll Tom, Florquin Sandrine Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis Kidney international 2009;75 (1):52-59 [PubMed]
  • Wolthuis Esther K., Vlaar Alexander P. J., Choi Goda, Roelofs Joris J. T. H., Haitsma Jack J., van der Poll Tom, Juffermans Nicole P., Zweers Machteld M., Schultz Marcus J. Recombinant human soluble tumor necrosis factor-alpha receptor fusion protein partly attenuates ventilator-induced lung injury Shock (Augusta, Ga.) 2009;31 (3):262-266 [PubMed]
  • Hovius Joppe W. R., Bijlsma Maarten F., van der Windt Gerritje J. W., Wiersinga W. Joost, Boukens Bastiaan J. D., Coumou Jeroen, Oei Anneke, de Beer Regina, de Vos Alex F., van 't Veer Cornelis, van Dam Alje P., Wang Penghua, Fikrig Erol, Levi Marcel M., Roelofs Joris J. T. H., van der Poll Tom The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi PLoS pathogens 2009;5 (5):e1000447 [PubMed]
  • Roelofs Joris J., Florquin Sandrine Tubulointerstitial Injury in IgA Nephropathyin: K. N. Lai, editors. Recent Advances in IgA Nephropathy. Hong Kong, China: World Scientific Publishing Co. Pte. Ltd.; 2009. p. 55-68, ISBN 9789812835864

2008

  • Renckens Rosemarijn, van Westerloo David J., Roelofs Joris J. T. H., Pater Jennie M., Schultz Marcus J., Florquin Sandrine, van der Poll Tom Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice Critical care medicine 2008;36 (2):580-587 [PubMed]
  • Choi Goda, Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., Rijneveld Anita W., Bresser Paul, van der Zee Jaring S., Florquin Sandrine, van der Poll Tom, Levi Marcel, Schultz Marcus J. Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats Critical care medicine 2008;36 (1):204-210 [PubMed]
  • Wiersinga W. Joost, de Vos Alex F., Wieland Catharina W., Leendertse Masja, Roelofs Joris J. T. H., van der Poll Tom CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice Journal of infectious diseases 2008;198 (9):1388-1397 [PubMed]
  • Roelofs Joris J., Abramowicz Daniel, Florquin Sandrine Immunomodulators: interleukins, interferons, and IV immunoglobulinin: Marc E. De Broe, George A. Porter, William M. Bennett, Gilbert Deray, editors. Clinical Nephrotoxins - Renal Injury from Drugs and Chemicals, Third Edition. Springer; 2008. p. 683-698, ISBN 9780387848426
  • Wiersinga W. Joost, de Vos Alex F., de Beer Regina, Wieland Catharina W., Roelofs Joris J. T. H., Woods Donald E., van der Poll Tom Inflammation patterns induced by different Burkholderia species in mice Cellular microbiology 2008;10 (1):81-87 [PubMed]
  • Wiersinga W. Joost, Wieland Catharina W., Roelofs Joris J. T. H., van der Poll Tom MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei PLoS ONE 2008;3 (10):e3494 [PubMed]
  • Hovius J. W., Schuijt T. J., de Groot K. A., Roelofs J. J. T. H., Oei G. A., Marquart J. A., de Beer R., van 't Veer C., van der Poll T., Ramamoorthi N., Fikrig E., van Dam A. P. Preferential protection of Borrelia burgdorferi sensu stricto by a Salp15 homologue in Ixodes ricinus saliva Journal of infectious diseases 2008;198 (8):1189-1197 [PubMed]
  • Pulskens Wilco P., Teske Gwendoline J., Butter Loes M., Roelofs Joris J., van der Poll Tom, Florquin Sandrine, Leemans Jaklien C. Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury PLoS ONE 2008;3 (10):e3596 [PubMed]
  • Renckens R., Roelofs J. J. T. H., Stegenga M. E., Florquin S., Levi M. [=Marcel M.], Carmeliet P., van't Veer C., van der Poll T. Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia Journal of thrombosis and haemostasis 2008;6 (4):660-668 [PubMed]

2007

  • Renckens Rosemarijn, Roelofs Joris J. T. H., Bonta Peter I., Florquin Sandrine, de Vries Carlie J. M., Levi Marcel, Carmeliet Peter, van't Veer Cornelis, van der Poll Tom Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia Blood 2007;109 (4):1593-1601 [PubMed]
  • Choi Goda, Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., Florquin Sandrine, Bresser Paul, Levi Marcel, van der Poll Tom, Schultz Marcus J. Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats Critical care medicine 2007;35 (5):1362-1368 [PubMed]
  • Roelofs J. J. T. H. The fibrinolytic system in renal disease 2007. 157p. ISBN 9789090219110. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin Sandrine, Weening Jan J.)

2006

  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Pater Jennie M., Lijnen H. Roger, Carmeliet Peter, van 't Veer Cornelis, van der Poll Tom Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice Journal of immunology (Baltimore, Md. 2006;177 (2):1189-1196 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Lijnen H. Roger, van't Veer Cornelis, van der Poll Tom Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis Journal of immunology (Baltimore, Md. 2006;176 (6):3735-3741 [PubMed]
  • Rouschop K. M. A., Roelofs J. J. T. H., Sylva M., Rowshani A. T., ten Berge I. J. M., Weening J. J., Florquin S. Renal expression of CD44 correlates with acute renal allograft rejection Kidney international 2006;70 (6):1127-1134 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Knapp Sylvia, de Vos Alex F., Florquin Sandrine, van der Poll Tom The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii Pneumonia Journal of infectious diseases 2006;193 (2):187-195 [PubMed]
  • Roelofs J. J. T. H., Rouschop K. M. A., Teske G. J. D., Claessen N., Weening J. J., van der Poll T., Florquin S. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis Kidney international 2006;70 (11):1942-1947 [PubMed]
  • Roelofs Joris J. T. H., Rouschop Kasper M. A., Leemans Jaklien C., Claessen Nike, de Boer Anita M., Frederiks Wilma M., Lijnen H. Roger, Weening Jan J., Florquin Sandrine Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury Journal of the American Society of Nephrology 2006;17 (1):131-140 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, van der Poll Tom Urokinase-type plasminogen activator receptor plays a role in neutrophil migration during lipopolysaccharide-induced peritoneal inflammation but not during Escherichia coli-induced peritonitis Journal of infectious diseases 2006;193 (4):522-530 [PubMed]

2005

  • Renckens Rosemarijn, Roelofs Joris J. T. H., ter Horst Simone A. J., van 't Veer Cornelis, Havik Stefan R., Florquin Sandrine, Wagenaar Gerry T. M., Meijers Joost C. M., van der Poll Tom Absence of thrombin-activatable fibrinolysis inhibitor protects against sepsis-induced liver injury in mice Journal of immunology (Baltimore, Md. 2005;175 (10):6764-6771 [PubMed]
  • Rouschop Kasper M. A., Roelofs Joris J. T. H., Rowshani Ajda T., Leemans Jaklien C., van der Poll Tom, ten Berge Ineke J. M., Weening Jan J., Florquin Sandrine Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection Nephrology, dialysis, transplantation 2005;20 (10):2248-2254 [PubMed]
  • Rouschop Kasper M. A., Roelofs Joris J. T. H., Claessen Nike, da Costa Martins Paula, Zwaginga Jaap-Jan, Pals Steven T., Weening Jan J., Florquin Sandrine Protection against renal ischemia reperfusion injury by CD44 disruption Journal of the American Society of Nephrology 2005;16 (7):2034-2043 [PubMed]
  • Renckens R., Roelofs J. J. T. H., de Waard V., Florquin S., Lijnen H. R., Carmeliet P., van der Poll T. The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injury Journal of thrombosis and haemostasis 2005;3 (5):1018-1025 [PubMed]

2004

  • Rouschop Kasper M. A., Sewnath Miguel E., Claessen Nike, Roelofs Joris J. T. H., Hoedemaeker Inge, van der Neut Ronald, Aten Jan, Pals Steven T., Weening Jan J., Florquin Sandrine CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy Journal of the American Society of Nephrology 2004;15 (3):674-686 [PubMed]

2003

  • Roelofs Joris J. T. H., Rowshani Ajda T., van den Berg José G., Claessen Nike, Aten Jan, ten Berge Ineke J. M., Weening Jan J., Florquin Sandrine Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection Kidney international 2003;64 (5):1845-1853 [PubMed]