MD PhD R.A.F.M. Chamuleau publications

foto

Publications MD PhD R.A.F.M. Chamuleau

Position
Associate Professor
Main activities
Research, Other
Specialisation
Hepatology
Focus of research

 Pathophysiology and treatment of severe liver failure.

Development of a bioartificial liver charged with human liver cells able to support severe liver patients either to transplantation or recovery of the diseased liver.

Study of the mechanisms of liver regeneration and the influence of the bioartificial liver on it.

Development of a prognostic index to predict the course of acute liver failure.

Search for specific breathprints of exhaled air by eNose in patients with liver disease.

2020

  • Adam Aziza A. A., Jongejan Aldo, Moerland Perry D., van der Mark Vincent A., Oude Elferink Ronald P., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Genome-wide expression profiling reveals increased stability and mitochondrial energy metabolism of the human liver cell line HepaRG-CAR Cytotechnology 2020 [PubMed]

2019

  • Chamuleau Robert A. F. M., Hoekstra Ruurdtje End-stage liver failure: filling the treatment gap at the intensive care unit Journal of Artificial Organs 2019 [PubMed]
  • Adam Aziza A. A., van der Mark Vincent A., Ruiter Jos P. N., Wanders Ronald J. A., Oude Elferink Ronald P. J., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Overexpression of carbamoyl-phosphate synthase 1 significantly improves ureagenesis of human liver HepaRG cells only when cultured under shaking conditions Mitochondrion 2019;47:298-308 [PubMed]
  • Adam Aziza A. A. The role of mitochondria in human liver cell line differentiation for bioartificial livers 2019. 221p. ISBN 9789492679895. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Oude Elferink R. P. J.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)

2018

  • Adam Aziza A. A., van Wenum Martien, van der Mark Vincent A., Jongejan Aldo, Moerland Perry D., Houtkooper Riekelt H., Wanders Ronald J. A., Oude Elferink Ronald P., Chamuleau Robert A. F. M., Hoekstra Ruurdtje AMC-Bio-Artificial Liver culturing enhances mitochondrial biogenesis in human liver cell lines: The role of oxygen, medium perfusion and 3D configuration Mitochondrion 2018;39:30-42 [PubMed]
  • Adam Aziza A. A., van der Mark Vincent A., Donkers Joanne M., Wildenberg Manon E., Oude Elferink Ronald P. J., Chamuleau Robert A. F. M., Hoekstra Ruurdtje A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines PLoS ONE 2018;13 (4) [PubMed]
  • van Wenum Martien, Treskes Philipp, Adam Aziza A. A., van der Mark Vincent. A., Jongejan Aldo, Moerland Perry D., van Gulik Thomas M., Oude Elferink Ronald P. J., Chamuleau Robert A. F. M., Hoekstra Ruurdtje HepaRG-Progenitor Cell Derived Hepatocytes Cultured in Bioartificial Livers Are Protected from Healthy- and Acute Liver Failure-Plasma Induced Toxicity Cellular physiology and biochemistry 2018;48 (5):2189-2204 [PubMed]
  • van Wenum Martien, Adam Aziza A. A., van der Mark Vincent A., Chang Jung-Chin, Wildenberg Manon E., Hendriks Erik J., Jongejan Aldo, Moerland Perry D., van Gulik Thomas M., Oude Elferink Ronald P., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines Journal of cell communication and signaling 2018;12 (3):575 [PubMed]
  • van Wenum Martinus Preclinical development of the AMC-HepaRG-Bioartificial Liver 2018. ISBN 9789462339248. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik T. M.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)

2017

  • Moedas M. F., Adam A. A. A., Farelo M. A., IJlst L., Chamuleau R. A. F. M., Hoekstra R., Wanders R. J. A., Silva M. F. B. Advances in methods for characterization of hepatic urea cycle enzymatic activity in HepaRG cells using UPLC-MS/MS Analytical biochemistry 2017;535:47-55 [PubMed]
  • van Wenum Martien, Treskes Philipp, Tang Chung-Yin, Coppens Esmee J., Jansen Koen, Hendriks Erik J., Camus Sandrine, van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Scaling-up of a HepaRG progenitor cell based bioartificial liver: optimization for clinical application and transport BIOFABRICATION 2017;9 (3):035001 [PubMed]
  • van der Mark Vincent A., Rudi de Waart D., Shevchenko Valery, Elferink Ronald P. J. Oude, Chamuleau Robert A. F. M., Hoekstra Ruurdtje Stable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG Cells Drug metabolism and disposition: the biological fate of chemicals 2017;45 (1):56-67 [PubMed]

2016

  • van Wenum Martien, Adam Aziza A. A., Hakvoort Theodorus B. M., Hendriks Erik J., Shevchenko Valery, van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Selecting Cells for Bioartificial Liver Devices and the Importance of a 3D Culture Environment: A Functional Comparison between the HepaRG and C3A Cell Lines International journal of biological sciences 2016;12 (8):964-978 [PubMed]

2015

  • Hoekstra R., van Wenum M., Chamuleau R. A. F. M. Pivotal preclinical trial of the spheroid reservoir bioartificial liver Journal of hepatology 2015;63 (4):1051-1052 [PubMed]

2014

  • Wlodzimirow Kama A., Eslami Saeid, Abu-Hanna Ameen, Nieuwoudt Martin, Chamuleau Robert A. F. M. A Systematic Review on Prognostic Indicators of Acute Liver Failure and Their Predictive Value for Poor Outcome British journal of medicine and medical research 2014;4 (15):2796-2852
  • van Wenum Martien, Chamuleau Robert Afm, van Gulik Thomas M., Siliakus Adriaan, Seppen Jurgen, Hoekstra Ruurdtje Bioartificial livers in vitro and in vivo: tailoring biocomponents to the expanding variety of applications Expert opinion on biological therapy 2014;14 (12):1745-1760 [PubMed]
  • Wlodzimirow K. A., Abu-Hanna A., Schultz M. J., Maas M. A. W., Bos L. D. J., Sterk P. J., Knobel H. H., Soers R. J. T., Chamuleau Robert A. F. M. Exhaled breath analysis with electronic nose technology for detection of acute liver failure in rats Biosensors & bioelectronics 2014;53:129-134 [PubMed]

2013

  • Wlodzimirow Kama A. Acute liver failure and acute kidney injury - definitions, prognosis, and outcome 2013. 203p. ISBN 9788393792009. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Abu-Hanna A., Schultz M. J.; Co-supervisor: Chamuleau R. A. F. M.)
  • Wlodzimirow Kama, Abu-Hanna Ameen, Chamuleau Robert A. F. M. Acute-on-chronic liver failure - its definition remains unclear Journal of hepatology 2013;59 (1):190-191 [PubMed]
  • Wlodzimirow Kama A., Eslami Saeid, Abu-Hanna Ameen, Nieuwoudt Martin, Chamuleau Robert A. F. M. A systematic review on prognostic indicators of acute on chronic liver failure and their predictive value for mortality Liver international 2013;33 (1):40-52 [PubMed]
  • Nibourg Geert A. A., Hoekstra Ruurdtje, van der Hoeven Tessa V., Ackermans Mariette T., Hakvoort Theodorus B. M., van Gulik Thomas M., Chamuleau Robert A. F. M. Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-bioartificial liver Liver international 2013;33 (4):516-524 [PubMed]
  • Nibourg Geert A. A., Hoekstra Ruurdtje, van der Hoeven Tessa V., Ackermans Mariëtte T., Hakvoort Theodorus B. M., van Gulik Thomas M., Chamuleau Robert A. F. M. Increased hepatic functionality of the human hepatoma cell line HepaRG cultured in the AMC bioreactor international journal of biochemistry & cell biology 2013;45 (8):1860-1868 [PubMed]
  • Hoekstra Ruurdtje, Nibourg Geert A. A., van der Hoeven Tessa V., Plomer Gabrielle, Seppen Jurgen, Ackermans Mariëtte T., Camus Sandrine, Kulik Wim, van Gulik Thomas M., Elferink Ronald P. Oude, Chamuleau Robert A. F. M. Phase 1 and phase 2 drug metabolism and bile acid production of HepaRG cells in a bioartificial liver in absence of dimethyl sulfoxide Drug metabolism and disposition: the biological fate of chemicals 2013;41 (3):562-567 [PubMed]

2012

  • Wlodzimirow Kama A., Abu-Hanna Ameen, Slabbekoorn Mathilde, Chamuleau Robert A. F. M., Schultz Marcus J., Bouman Catherine S. C. A comparison of RIFLE with and without urine output criteria for acute kidney injury in critically ill patients Critical care (London, England) 2012;16 (5):R200 [PubMed]
  • Wlodzimirow Kama A., Eslami Saeid, Abu-Hanna Ameen, Nieuwoudt Martin, Chamuleau Robert A. F. M. Acute liver failure: What is it? Hepatology (Baltimore, Md.) 2012;55 (4):1306-1307 [PubMed]
  • Hoekstra Lisette T., van Lienden Krijn P., Schaap Frank G., Chamuleau Rob A. F. M., Bennink Roel J., van Gulik Thomas M. Can Plasma Bile Salt, Triglycerides, and apoA-V Levels Predict Liver Regeneration? World journal of surgery 2012;36 (12):2901-2908 [PubMed]
  • Nibourg Geert A. A. Human liver cell lines for the AMC-bioarteficial liver 2012. 236p. ISBN 9789461083609. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik T. M.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)
  • Chamuleau Robert A. F. M., Wlodzimirow Kama A., Abu-Hanna Ameen Incorporating dynamics for predicting poor outcome in acute liver failure patients World journal of gastrointestinal surgery 2012;4 (12):281-283 [PubMed]
  • Nibourg Geert A. A., Chamuleau Robert A. F. M., van der Hoeven Tessa V., Maas Martinus A. W., Ruiter An F. C., Lamers Wouter H., Oude Elferink Ronald P. J., van Gulik Thomas M., Hoekstra Ruurdtje Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure PLoS ONE 2012;7 (6):e38778 [PubMed]
  • Nibourg Geert A. A., Boer Justin D., van der Hoeven Tessa V., Ackermans Mariëtte T., van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Perfusion flow rate substantially contributes to the performance of the HepaRG-AMC-bioartificial liver Biotechnology and bioengineering 2012;109 (12):3182-3188 [PubMed]
  • Wlodzimirow Kama A., Eslami Saeid, Chamuleau Robert A. F. M., Nieuwoudt Martin, Abu-Hanna Ameen Prediction of Poor Outcome in Patients with Acute Liver Failure-Systematic Review of Prediction Models PLoS ONE 2012;7 (12):e50952 [PubMed]
  • Nibourg Geert A. A., Chamuleau Robert A. F. M., van Gulik Thomas M., Hoekstra Ruurdtje Proliferative human cell sources applied as biocomponent in bioartificial livers: a review Expert opinion on biological therapy 2012;12 (7):905-921 [PubMed]
  • Wlodzimirow K. A., Eslami S., Abu-Hanna A., Nieuwoudt M., Chamuleau R. A. F. M. Systematic review: acute liver failure - one disease, more than 40 definitions Alimentary pharmacology & therapeutics 2012;35 (11):1245-1256 [PubMed]
  • Hoekstra Ruurdtje, Nibourg Geert A. A., van der Hoeven Tessa V., Ackermans Mariëtte T., Hakvoort Theodorus B. M., van Gulik Thomas M., Oude Elferink Ronald P., Chamuleau Robert A. F. M. The effect of rat acute-liver-failure plasma on HepaRG cells International journal of artificial organs 2012;35 (11):1006-1014 [PubMed]

2011

  • Hoekstra Ruurdtje, Nibourg Geert A. A., van der Hoeven Tessa V., Ackermans Mariëtte T., Hakvoort Theodorus B. M., van Gulik Thomas M., Lamers Wouter H., Elferink Ronald P. Oude, Chamuleau Robert A. F. M. The HepaRG cell line is suitable for bioartificial liver application international journal of biochemistry & cell biology 2011;43 (10):1483-1489 [PubMed]

2010

  • Andria B., Bracco A., Cirino G., Chamuleau R. A. F. M. Liver Cell Culture Devices Cell medicine 2010;1 (1):55-70 [PubMed]
  • Di Nicuolo Giuseppe, D'Alessandro Alba, Andria Barbara, Scuderi Vincenzo, Scognamiglio Michele, Tammaro Angela, Mancini Antonio, Cozzolino Santolo, di Florio Ernesto, Bracco Adele, Calise Fulvio, Chamuleau Robert A. F. M. Long-term absence of porcine endogenous retrovirus infection in chronically immunosuppressed patients after treatment with the porcine cell-based Academic Medical Center bioartificial liver Xenotransplantation 2010;17 (6):431-439 [PubMed]
  • Nibourg Geert A. A., Huisman Maarten T., van der Hoeven Tessa V., van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Stable Overexpression of Pregnane X Receptor in HepG2 Cells Increases Its Potential for Bioartificial Liver Application Liver transplantation 2010;16 (9):1075-1085 [PubMed]

2009

  • Chamuleau Robert A. F. M. Future of bioartificial liver support World journal of gastrointestinal surgery 2009;1 (1):21-25 [PubMed]
  • Deurholt Tanja, van Til Niek P., Chhatta Aniska A., ten Bloemendaal Lysbeth, Schwartlander Ruth, Payne Catherine, Plevris John N., Sauer Igor M., Chamuleau Robert A. F. M., Oude Elferink Ronald P. J., Seppen Jurgen, Hoekstra Ruurdtje Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes BMC biotechnology 2009;9 (1):89 [PubMed]

2008

  • Poyck Paul P. C., Mareels Guy, Hoekstra Ruurdtje, van Wijk Albert C. W. A., van der Hoeven Tessa V., van Gulik Thomas M., Verdonck Pascal R., Chamuleau Robert A. F. M. Enhanced oxygen availability improves liver-specific functions of the AMC bioartificial liver Artificial organs 2008;32 (2):116-126 [PubMed]
  • Poyck Paul P. C., van Wijk Albert C. W. A., van der Hoeven Tessa V., de Waart Dirk R., Chamuleau Robert A. F. M., van Gulik Thomas M., Oude Elferink Ronald P. J., Hoekstra Ruurdtje Evaluation of a new immortalized human fetal liver cell line (cBAL111) for application in bioartificial liver Journal of hepatology 2008;48 (2):266-275 [PubMed]
  • Poyck Paul P. C., Hoekstra Ruurdtje, Vermeulen Jacqueline L. M., van Wijk Albert C. W. A., Chamuleau Robert A. F. M., Hakvoort Theodorus B. M., van Gulik Thomas M., Lamers Wouter H. Expression of glutamine synthetase and carbamoylphosphate synthetase i in a bioartificial liver: markers for the development of zonation in vitro Cells, tissues, organs 2008;188 (3):259-269 [PubMed]

2007

  • Deurholt Tanja Development of an immortalised human hepatocyte cell line for the AMC bio-artificial liver 2007. 141p. ISBN 9789090225098. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Oude Elferink Ronald P. J.; Co-supervisors: Chamuleau Robert A. F. M., Hoekstra R.)
  • Poyck Paul P. C., Hoekstra Ruurdtje, van Wijk Albert C. W. A., Attanasio Chiara, Calise Fulvio, Chamuleau Robert A. F. M., van Gulik Thomas M. Functional and morphological comparison of three primary liver cell types cultured in the AMC bioartificial liver Liver transplantation 2007;13 (4):589-598 [PubMed]
  • Poyck P. P. C., Pless G., Hoekstra R., Roth S., van Wijk A. C. W. A., Schwartlander R., van Gulik T. M., Sauer I. M., Chamuleau R. A. F. M. In vitro comparison of two bioartificial liver support systems: MELS CellModule and AMC-BAL International journal of artificial organs 2007;30 (3):183-191 [PubMed]
  • Chamuleau R. A. F. M. Recente ontwikkelingen in de behandeling van chronische hepatitis B en C Nederlands tijdschrift voor tandheelkunde 2007;114 (8):353-356 [PubMed]
  • Poyck Paul P. C., Hoekstra Ruurdtje, Chhatta Aniska, ten Bloemendaal Lysbeth, van Wijk Albert C. W. A., Galavotti Daniele, van Gulik Thomas M., Chamuleau Robert A. F. M. Time-related analysis of metabolic liver functions, cellular morphology, and gene expression of hepatocytes cultured in the bioartificial liver of the Academic Medical Center in Amsterdam (AMC-BAL) Tissue engineering 2007;13 (6):1235-1246 [PubMed]
  • Poyck Paul P. C. Towards application of a human liver cell line for use in the AMC bioartificial liver 2007. 351p. ISBN 9789090220505. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik Thomas M.; Co-supervisors: Chamuleau Robert A. F. M., Hoekstra Ruurdtje)

2006

  • Hoekstra Ruurdtje, Deurholt Tanja, ten Bloemendaal Lysbeth, Desille Mireille, van Wijk Albert C. W. A., Clement Bruno, Oude Elferink Ronald P. J., van Gulik Thomas M., Chamuleaut Robert A. F. M. Assessment of in vitro applicability of reversibly immortalized NKNT-3 cells and clonal derivatives Cell transplantation 2006;15 (5):423-433 [PubMed]
  • Chamuleau Robert A. F. M., Poyck Paul P. C., van de Kerkhove Maarten-Paul Bioartificial liver: its pros and cons Therapeutic apheresis and dialysis 2006;10 (2):168-174 [PubMed]
  • Schaap Frank G., Nierman Melchior C., Berbée Jimmy F. P., Hattori Hiroaki, Talmud Philippa J., Vaessen Stefan F. C., Rensen Patrick C. N., Chamuleau Robert A. F. M., Kuivenhoven Jan Albert, Groen Albert K. Evidence for a complex relationship between apoA-V and apoC-III in patients with severe hypertriglyceridemia Journal of lipid research 2006;47 (10):2333-2339 [PubMed]
  • Chamuleau R. A. F. M., Poyck P. P. C. Hepatic encephalopathy and artificial liver support systemsin: D. Häussinger, G. Kirchels, F. Schliess, editors. Hepatic encephalopathy and nitrogen metabolism. S.l.: Springer; 2006. p. 523-ev
  • Deurholt Tanja, ten Bloemendaal Lysbeth, Chhatta Aniska A., van Wijk Albert C. W. A., Weijer Kees, Seppen Jurgen, Elferink Ronald P. J. Oude, Chamuleau Robert A. F. M., Hoekstra Ruurdtje In vitro functionality of human fetal liver cells and clonal derivatives under proliferative conditions Cell transplantation 2006;15 (8-9):811-822 [PubMed]
  • van de Kerkhove M. P., Hoekstra R., van Nooijen F. C., Spoelstra F. O. B., Doorschodt B. M., van Wijk A. C. W. A., Poyck P. P. C., Chamuleau R. A. F. M., van Gulik T. M. Subnormothermic preservation maintains viability and function in a porcine hepatocyte culture model simulating bioreactor transport Cell transplantation 2006;15 (2):161-168 [PubMed]
  • Chamuleau R. A. F. M. The Amsterdam bioartificial liverin: D. Henne-Bruns, K. Buttenschön, M. Fuchs, A. W. Lohse, editors. Artificial liver support. Dordrecht: Springer; 2006. p. 61-71, ISBN 9781402032394
  • Mareels Guy, Poyck Paul P. C., Eloot Sunny, Chamuleau Robert A. F. M., Verdonck Pascal R. Three-dimensional numerical modeling and computational fluid dynamics simulations to analyze and improve oxygen availability in the AMC bioartificial liver Annals of biomedical engineering 2006;34 (11):1729-1744 [PubMed]

2005

  • van de Kerkhove M. P., Poyck P. P. C., van Wijk A. C. W. A., Galavotti D., Hoekstra R., van Gulik T. M., Chamuleau R. A. F. M. Assessment and improvement of liver specific function of the AMC-bioartificial liver International journal of artificial organs 2005;28 (6):617-630 [PubMed]
  • van de Kerkhove Maarten-Paul, Germans Menno R., Deurholt Tanja, Hoekstra Ruurdtje, Joziasse David H., van Wijk Albert C. W. A., van Gulik Thomas M., Chamuleau Robert A. F. M., Roos Anja Evidence for Galalpha(1-3)Gal expression on primary porcine hepatocytes: implications for bioartificial liver systems Journal of hepatology 2005;42 (4):541-547 [PubMed]
  • Chamuleau R. A. F. M. 'Kunstmatige ondersteuning bij leverfalen'; een signalement van de Gezondheidsraad Nederlands tijdschrift voor geneeskunde 2005;149 (5):221-ev [PubMed]
  • van de Kerkhove M. P., Poyck P. P. C., Deurholt T., Hoekstra R., Chamuleau R. A. F. M., van Gulik T. M. Liver support therapy: an overview of the AMC-bioartificial liver research Digestive surgery 2005;22 (4):254-264 [PubMed]
  • Poyck Paul P. C., Hoekstra Ruurdtje, van Wijk Albert C. W. A., ten Bloemendaal Lysbeth, Chamuleau Robert A. F. M., van Gulik Thomas M. Mild hypothermic preservation for transport purposes of the AMC bioartificial liver charged with porcine hepatocytes Transplantation 2005;80 (9):1153-1160 [PubMed]
  • Di Nicuolo Giuseppe, van de Kerkhove Maarten-Paul, Hoekstra Ruurdtje, Beld Marcel G. H. M., Amoroso Pietro, Battisti Sonia, Starace Maria, di Florio Ernesto, Scuderi Vincenzo, Scala Simona, Bracco Adele, Mancini Antonio, Chamuleau Robert A. F. M., Calise Fulvio No evidence of in vitro and in vivo porcine endogenous retrovirus infection after plasmapheresis through the AMC-bioartificial liver Xenotransplantation 2005;12 (4):286-292 [PubMed]
  • Jansen M. C., van Hillegersberg R., Chamuleau R. A. F. M., van Delden O. M., Gouma D. J., van Gulik T. M. Outcome of regional and local ablative therapies for hepatocellular carcinoma: a collective review European journal of surgical oncology 2005;31 (4):331-347 [PubMed]
  • Chamuleau Robert A. F. M., Deurholt Tanja, Hoekstra Ruurdtje Which are the right cells to be used in a bioartificial liver? Metabolic brain disease 2005;20 (4):327-335 [PubMed]

2004

  • Schaap Frank G., Rensen Patrick C. N., Voshol Peter J., Vrins Carlos, van der Vliet Hendrik N., Chamuleau Robert A. F. M., Havekes Louis M., Groen Albert K., van Dijk Ko Willems ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis Journal of biological chemistry 2004;279 (27):27941-27947 [PubMed]
  • van de Kerkhove Maarten Paul, Hoekstra Ruurdtje, Chamuleau Robert A. F. M., van Gulik Thomas M. Clinical application of bioartificial liver support systems Annals of surgery 2004;240 (2):216-230 [PubMed]
  • van de Kerkhove M.-P., Hoekstra R., van Gulik T. M., Chamuleau R. A. F. M. Large animal models of fulminant hepatic failure in artificial and bioartificial liver support research Biomaterials 2004;25 (9):1613-1625 [PubMed]
  • van de Kerkhove M. P. Optimization and clinical application of the AMC-bioarteficial liver 2004. 187p. ISBN 9789090479378. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik T. M.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)

2003

  • Weegink Christine J., Sentjens Roel E., van der Heyden Jeroen F., Chamuleau Robert A., Tytgat Guido N., Beld Marcel G. A physician with a positive hepatitis C virus RNA test after a needlestick injury European journal of gastroenterology & hepatology 2003;15 (12):1367-1369 [PubMed]
  • Chamuleau Robert A. F. M. Artificial liver support in the third millennium ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY 2003;31 (2):117-126 [PubMed]
  • Sosef M. N., van de Kerkhove M.-P., Abrahamse S. L., Levi M. M., Chamuleau R. A. F. M., van Gulik T. M. Blood coagulation in anhepatic pigs: effects of treatment with the AMC-bioartificial liver Journal of thrombosis and haemostasis 2003;1 (3):511-515 [PubMed]
  • van de Kerkhove Maarten-Paul, di Florio Ernesto, Scuderi Vincenzo, Mancini Antonio, Belli Antonello, Bracco Adele, Scala Daniela, Scala Simona, Zeuli Laura, Di Nicuolo Giuseppe, Amoroso Pietro, Calise Fulvio, Chamuleau Robert A. F. M. Bridging a patient with acute liver failure to liver transplantation by the AMC-bioartificial liver Cell transplantation 2003;12 (6):563-568 [PubMed]
  • van de Kerkhove M. P., Chamuleau R. A. F. M., van Gulik T. M. Clinical application of bioartificial liver support systems (chapter 38)in: E. A. Jones, A. J. Meijer, R. A. F. M. Chamuleau, editors. Encephalopahty and nitrogen metabolism in liver failure. London: Kluwer Academic Publishers; 2003. p. 389, ISBN 9781402011573
  • Jones E. A., Meijer A. J., Chamuleau R. A. F. M. Encephalopathy and nitrogen metabolism in liver failureDordrecht, Boston, London: Kluwer Academic Publishers; 2003. ISBN 9781402011573
  • Sosef M. N. Experimental treatment modalities for liver failure 2003. 147p. ISBN 9789090175621. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik T. M.; Co-supervisor: Chamuleau R. A. F. M.)
  • Abrahamse Salomon L., van Runnard Heimel Pieter, Hartman Robin J., Chamuleau Rob A. F. M., van Gulik Thomas M. Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions Cell transplantation 2003;12 (1):59-68 [PubMed]

2002

  • van der Vliet Hendrik N., Schaap Frank G., Levels Johannes H. M., Ottenhoff Roelof, Looije Norbert, Wesseling John G., Groen Albert K., Chamuleau Robert A. F. M. Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice Biochemical and biophysical research communications 2002;295 (5):1156-1159 [PubMed]
  • Sosef Meindert N., Abrahamse Leo S. L., van de Kerkhove Maarten-Paul, Hartman Robin, Chamuleau Rob A. F. M., van Gulik Thomas M. Assessment of the AMC-bioartificial liver in the anhepatic pig Transplantation 2002;73 (2):204-209 [PubMed]
  • Chamuleau Robert A. F. M. Bioartificial liver support anno 2001 Metabolic brain disease 2002;17 (4):485-491 [PubMed]
  • van de Kerkhove M. P., Di Florio E., Scuderi V., Mancini A., Belli A., Bracco A., Dauri M., Tisone G., Di Nicuolo G., Amoroso P., Spadari A., Lombardi G., Hoekstra R., Calise F., Chamuleau R. A. F. M. Phase I clinical trial with the AMC-bioartificial liver International journal of artificial organs 2002;25 (10):950-959 [PubMed]
  • Hoekstra R., Chamuleau R. A. F. M. Recent developments on human cell lines for the bioartificial liver International journal of artificial organs 2002;25 (3):182-191 [PubMed]
  • Abrahamse S. L., van de Kerkhove M. P., Sosef M. N., Hartman R., Chamuleau R. A. F. M., van Gulik T. M. Treatment of acute liver failure in pigs reduces hepatocyte function in a bioartificial liver support system International journal of artificial organs 2002;25 (10):966-974 [PubMed]

2001

  • van der Vliet H. N., Sammels M. G., Leegwater A. C., Levels J. H., Reitsma P. H., Boers W., Chamuleau R. A. Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration Journal of biological chemistry 2001;276 (48):44512-44520 [PubMed]
  • Weegink C. J., Chamuleau R. A., Reesink H. W., Molenaar D. S. Development of myasthenia gravis during treatment of chronic hepatitis C with interferon-alpha and ribavirin Journal of gastroenterology 2001;36 (10):723-724 [PubMed]
  • Janssen H. L., Wijnhoud A., Haagsma E. B., van Uum S. H., van Nieuwkerk C. M., Adang R. P., Chamuleau R. A., van Hattum J., Vleggaar F. P., Hansen B. E., Rosendaal F. R., van Hoek B. Extrahepatic portal vein thrombosis: aetiology and determinants of survival Gut 2001;49 (5):720-724 [PubMed]
  • Calise F., Mancini A., Amoroso P., Belli A., Bracco A., Ceriello A., Di Florio E., Di Nicuolo G., Di Martino A., Maida P., Scala D., Zeuli L., Chamuleau R. A. Functional evaluation of the AMC-BAL to be employed in a multicentric clinical trial for acute liver failure Transplantation proceedings 2001;33 (1-2):647-649 [PubMed]
  • Damen M., Weegink C. J., Mauser-Bunschoten E. P., Cuypers H. T., Hermus M. C., Sillekens P., Haan E., van den Berg H. M., Bresters D., Lelie P. N., Chamuleau R. A., Reesink H. W. Sustained virological response in chronic hepatitis C patients after a 6- and a 36-month interferon-alpha2b treatment schedule: a multicenter, randomized, controlled study Scandinavian journal of gastroenterology 2001;36 (1):97-104 [PubMed]

2000

  • A survey of liver pathology in needle biopsies from HBsAg and anti-HBe positive individuals Journal of clinical pathology 2000;53 (7):541-548 [PubMed]
  • Factor V Leiden mutation, prothrombin gene mutation, and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis: results of a case-control study Blood 2000;96 (7):2364-2368 [PubMed]

1999

  • Combination therapy with mycophenolate mofetil and ursodeoxycholic acid for primary biliary cirrhosis European journal of gastroenterology & hepatology 1999;11 (10):1165-1169 [PubMed]
  • Effects of a branched-chain amino acid-enriched diet on chronic hepatic encephalopathy in dogs Metabolic brain disease 1999;14 (2):103-115 [PubMed]
  • Evaluation of a novel bioartificial liver in rats with complete liver ischemia: treatment efficacy and species-specific alpha-GST detection to monitor hepatocyte viability Journal of hepatology 1999;30 (2):311-320 [PubMed]
  • Significantly improved survival time in pigs with complete liver ischemia treated with a novel bioartificial liver International journal of artificial organs 1999;22 (10):701-709 [PubMed]

1998

  • Changes in urinary taurine and hypotaurine excretion after two-thirds hepatectomy in the rat Amino acids 1998;15 (4):373-383 [PubMed]
  • Changing patterns of gene expression in the pulmonary trunk-banded rat heart Journal of molecular and cellular cardiology 1998;30 (9):1877-1888 [PubMed]
  • Commercially available media for flushing extracorporeal bioartificial liver systems prior to connection to the patient's circulation: an in vitro comparative study in two and three dimensional porcine hepatocyte cultures International journal of artificial organs 1998;21 (8):467-472 [PubMed]
  • Does the extend of the culture time of primary hepatocytes in a bioreactor affect the treatment efficacy of a bioartificial liver? International journal of artificial organs 1998;21 (9):542-547 [PubMed]
  • Efficacy of interferon dose and prediction of response in chronic hepatitis C: Benelux study in 336 patients Journal of hepatology 1998;28 (6):951-959 [PubMed]
  • Hepatitis C virus genotypes: epidemiological and clinical associations. Benelux Study Group on Treatment of Chronic Hepatitis C Liver 1998;18 (1):32-38 [PubMed]
  • Lever en kunstlever Nederlands tijdschrift voor geneeskunde 1998;142 (23):1300-1305 [PubMed]
  • Recovery from life-threatening, corticosteroid-unresponsive, chemotherapy-related reactivation of hepatitis B associated with lamivudine therapy Digestive diseases and sciences 1998;43 (10):2267-2270 [PubMed]
  • Relation between laboratory test results and histological hepatitis activity in individuals positive for hepatitis B surface antigen and antibodies to hepatitis B e antigen Lancet 1998;351 (9120):1914-1918 [PubMed]

1997

  • Correlation of repressed transcription of alpha-tocopherol transfer protein with serum alpha-tocopherol during hepatocarcinogenesis International journal of cancer. Journal international du cancer 1997;71 (4):686-690 [PubMed]
  • Effect of a protein-rich meal on urinary and salivary free amino acid concentrations in human subjects Clinica chimica acta; international journal of clinical chemistry 1997;264 (1):37-47 [PubMed]
  • Hyperammonaemia without portal systemic shunting does not resemble hepatic encephalopathy Advances in experimental medicine and biology 1997;420:173-183 [PubMed]
  • Immunological consequences of the use of xenogeneic hepatocytes in a bioartificial liver for acute liver failure International journal of artificial organs 1997;20 (4):229-233 [PubMed]
  • Increased hepatic ferritin-H messenger RNA levels correlate with those of c-myc in human hepatocellular carcinoma International journal of oncology 1997;11 (1):187-192 [PubMed]
  • In vitro evaluation of a novel bioreactor based on an integral oxygenator and a spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates Journal of hepatology 1997;26 (6):1379-1392 [PubMed]
  • L-ornithine vs. L-ornithine-L-aspartate as a treatment for hyperammonemia-induced encephalopathy in rats Journal of hepatology 1997;26 (1):174-182 [PubMed]
  • Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats Hepatology (Baltimore, Md.) 1997;25 (4):820-827 [PubMed]
  • No attenuation of ischemic and reperfusion injury in Kupffer cell-depleted, cold-preserved rat livers Transplantation 1997;63 (3):449-454 [PubMed]
  • Overexpression of hepatic prothymosin alpha, a novel marker for human hepatocellular carcinoma British journal of cancer 1997;76 (9):1199-1204 [PubMed]
  • Overexpression of prothymosin alpha, concomitant with c-myc, during rat hepatic carcinogenesis Biochemical and biophysical research communications 1997;232 (3):817-821 [PubMed]
  • Possible immunological problems of bioartificial liver support International journal of artificial organs 1997;20 (8):418-421 [PubMed]
  • Rat ferritin-H: cDNA cloning, differential expression and localization during hepatocarcinogenesis Carcinogenesis 1997;18 (1):47-52 [PubMed]
  • Semipermeable hollow fiber membranes in hepatocyte bioreactors: a prerequisite for a successful bioartificial liver? Artificial organs 1997;21 (11):1177-1181 [PubMed]
  • The effects of ammonia and portal-systemic shunting on brain metabolism, neurotransmission and intracranial hypertension in hyperammonaemia-induced encephalopathy Journal of hepatology 1997;26 (2):387-395 [PubMed]
  • Transforming growth factor-beta-induced collagen synthesis by human liver myofibroblasts is inhibited by alpha2-macroglobulin Journal of hepatology 1997;26 (6):1220-1228 [PubMed]

1996

  • Animal models of hepatic encephalopathy Seminars in liver disease 1996;16 (3):265-270 [PubMed]
  • Do serum ALAT values reflect the inflammatory activity in the liver of patients with chronic viral hepatitis? Liver 1996;16 (2):105-109 [PubMed]
  • Formation of antibodies to factor VIII in patients with hemophilia A who are treated with interferon for chronic hepatitis C Annals of internal medicine 1996;125 (4):297-299 [PubMed]
  • Hyaluronic acid uptake in the assessment of sinusoidal endothelial cell damage after cold storage and normothermic reperfusion of rat livers Transplant international 1996;9 (5):446-453 [PubMed]
  • Isolation of up- and down-regulated cDNAs associated with hepatocellular carcinoma by a subtraction-enhanced display technique BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1996;1315 (3):169-175 [PubMed]
  • Localization of alpha 2-macroglobulin protein and messenger RNA in rat liver fibrosis: evidence for the synthesis of alpha 2-macroglobulin within Schistosoma mansoni egg granulomas Hepatology (Baltimore, Md.) 1996;23 (5):1260-1267 [PubMed]
  • Significant improvement of survival by intrasplenic hepatocyte transplantation in totally hepatectomized rats Cell transplantation 1996;5 (3):369-378 [PubMed]
  • The use of hyaluronic acid uptake in the evaluation of reperfusion injury in cold stored rat livers Transplantation proceedings 1996;28 (1):75-76 [PubMed]

1995

  • Collagen synthesis by human liver (myo)fibroblasts in culture: evidence for a regulatory role of IL-1 beta, IL-4, TGF beta and IFN gamma Journal of hepatology 1995;23 (3):307-317 [PubMed]
  • Functional activity of isolated pig hepatocytes attached to different extracellular matrix substrates. Implication for application of pig hepatocytes in a bioartificial liver Journal of hepatology 1995;23 (2):184-192 [PubMed]
  • Interleukin-6 production by human liver (myo)fibroblasts in culture. Evidence for a regulatory role of LPS, IL-1 beta and TNF alpha Journal of hepatology 1995;23 (3):295-306 [PubMed]
  • In vivo amino acid fluxes in regenerating liver after two-thirds hepatectomy in the rat Journal of hepatology 1995;23 (3):333-340 [PubMed]
  • Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt Journal of neurochemistry 1995;64 (3):1238-1244 [PubMed]
  • The effect of extrahepatic cholestasis on liver regeneration after partial hepatectomy in the rat Liver 1995;15 (5):242-246 [PubMed]

1994

  • Cell-swelling-induced taurine release from isolated perfused rat liver Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72 (1-2):8-11 [PubMed]
  • Experimental colitis in rats induces low-grade endotoxinemia without hepatobiliary abnormalities Digestive diseases and sciences 1994;39 (6):1210-1215 [PubMed]
  • Identification of enriched sequences from a cDNA subtraction-hybridization procedure Nucleic acids research 1994;22 (5):878-879 [PubMed]
  • In vivo brain magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) in hepatic encephalopathy Advances in experimental medicine and biology 1994;368:23-31 [PubMed]
  • Lobular patterns of expression and enzyme activities of glutamine synthase, carbamoylphosphate synthase and glutamate dehydrogenase during postnatal development of the porcine liver BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1994;1200 (3):265-270 [PubMed]
  • The physiological position of the liver in the circulation is not a major determinant of its functional capacity Hepatology (Baltimore, Md.) 1994;20 (6):1532-1540 [PubMed]
  • Vascular branching pattern and zonation of gene expression in the mammalian liver. A comparative study in rat, mouse, cynomolgus monkey, and pig Anatomical record 1994;239 (4):441-452 [PubMed]

1993

  • Ammonium in intravenous albumin preparations Lancet 1993;342 (8879):1110-1111 [PubMed]
  • Distribution and activity of glutamine synthase and carbamoylphosphate synthase upon enlargement of the liver lobule by repeated partial hepatectomies Journal of hepatology 1993;17 (3):397-407 [PubMed]
  • Doppler radar device as a useful tool to quantify the liveliness of the experimental animal Medical & biological engineering & computing 1993;31 (4):340-342 [PubMed]
  • Experimental evidence that the physiological position of the liver within the circulation is not a major determinant of zonation of gene expression Hepatology (Baltimore, Md.) 1993;18 (5):1144-1153 [PubMed]
  • Long term treatment of chronic hepatitis C with interferon alfa-2b: disappearance of HCV-RNA in a pilot study of eight haemophilia patients Gut 1993;34 (2 Suppl):S124-S125 [PubMed]
  • Protective effect of silymarin on rat liver injury induced by ischemia Virchows Archiv. B, Cell pathology including molecular pathology 1993;64 (5):259-263 [PubMed]
  • Reversibility of cholestatic changes following experimental common bile duct obstruction: fact or fantasy? Journal of hepatology 1993;18 (1):85-95 [PubMed]
  • Sexual transmission of hepatitis C virus Lancet 1993;342 (8865):210-211 [PubMed]

1992

  • Adrenal hormones and the regulation of acute phase protein synthesis Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1992;30 (4):159-160 [PubMed]
  • Amino acid release from cerebral cortex in experimental acute liver failure, studied by in vivo cerebral cortex microdialysis Journal of neurochemistry 1992;59 (2):591-599 [PubMed]
  • Antiviral effect of prolonged intermittent lymphoblastoid alpha interferon treatment in chronic hepatitis B Gut 1992;33 (8):1094-1098 [PubMed]
  • Detection of hepatitis C viral RNA sequences in fresh and paraffin-embedded liver biopsy specimens of non-A, non-B hepatitis patients Journal of hepatology 1992;15 (3):391-395 [PubMed]
  • Hepatitis C; een nieuw virus voor een oude ziekte Nederlands tijdschrift voor geneeskunde 1992;136 (52):2560-2564 [PubMed]
  • Liver biopsy versus ultrasound in methotrexate-treated psoriasis: a decision analysis International journal of dermatology 1992;31 (6):404-409 [PubMed]
  • Reappearance of vanished bile ducts Hepato-gastroenterology 1992;39 (6):523-524 [PubMed]
  • Three different hepatocyte transplantation techniques for enzyme deficiency disease and acute hepatic failure Artificial organs 1992;16 (5):522-526 [PubMed]

1991

  • A localized in vivo detection method for lactate using zero quantum coherence techniques Magnetic resonance in medicine 1991;22 (2):493-498 [PubMed]
  • Celbiologie in medisch perspectief. IX. Cel-cel- en cel-matrixinteractie Nederlands tijdschrift voor geneeskunde 1991;135 (52):2469-2473 [PubMed]
  • Liver regeneration after partial hepatectomy in rats with defective bilirubin conjugation or biliary excretion Digestive diseases and sciences 1991;36 (4):510-512 [PubMed]
  • Prevalence of anti-HCV antibodies confirmed by recombinant immunoblot in different population subsets in The Netherlands Vox sanguinis 1991;61 (1):30-36 [PubMed]
  • The effects of benzodiazepine-receptor antagonists and partial inverse agonists on acute hepatic encephalopathy in the rat Gastroenterology 1991;101 (3):772-781 [PubMed]
  • The relationship between plasma free fatty acids and experimentally induced hepatic encephalopathy in the rat Clinica chimica acta; international journal of clinical chemistry 1991;197 (2):95-104 [PubMed]
  • The use of in vivo proton NMR to study the effects of hyperammonemia in the rat cerebral cortex NMR in biomedicine 1991;4 (1):31-37 [PubMed]
  • What the clinician can learn from MR glutamine/glutamate assays NMR in biomedicine 1991;4 (2):103-108 [PubMed]

1990

  • Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation Hepatology (Baltimore, Md.) 1990;12 (2):281-290 [PubMed]
  • Immunocytochemical determination of ploidy class-dependent bromodeoxyuridine incorporation in rat liver parenchymal cells after partial hepatectomy Histochemistry 1990;93 (6):627-630 [PubMed]
  • Leverceltransplantatie; een mogelijk alternatief voor levertransplantatie? Nederlands tijdschrift voor geneeskunde 1990;134 (14):685-688 [PubMed]
  • Leverregeneratie; niet alleen Heracles was Prometheus' redding Nederlands tijdschrift voor geneeskunde 1990;134 (12):582-586 [PubMed]
  • Liver regeneration and restoration of liver function after partial hepatectomy in patients with liver tumors Scandinavian journal of gastroenterology 1990;25 (2):112-118 [PubMed]
  • Meningococcus septicemia: a complication of endoscopic injection sclerotherapy American journal of gastroenterology 1990;85 (5):631-632 [PubMed]
  • Methanethiol metabolism and its role in the pathogenesis of hepatic encephalopathy in rats and dogs Hepatology (Baltimore, Md.) 1990;11 (4):682-689 [PubMed]
  • Nitrogen metabolism and ornithine cycle function Physiological reviews 1990;70 (3):701-748 [PubMed]
  • Use of 1H-NMR to determine the distribution of lecithin between the micellar and vesicular phases in model bile Journal of lipid research 1990;31 (7):1315-1321 [PubMed]

1989

  • Metabolic activity of microcarrier attached liver cells after intraperitoneal transplantation during severe liver insufficiency in the rat Journal of hepatology 1989;9 (1):49-58 [PubMed]

1988

  • In vivo 1H-NMR procedure to determine several rat cerebral metabolite levels simultaneously, undisturbed by water and lipid signals Magnetic resonance imaging 1988;6 (3):255-261 [PubMed]
  • In vivo 31P NMR spectroscopy of the rat cerebral cortex during acute hepatic encephalopathy NMR in biomedicine 1988;1 (2):101-106 [PubMed]
  • Is the magnetic resonance imaging proton spin-lattice relaxation time a reliable noninvasive parameter of developing liver fibrosis? Hepatology (Baltimore, Md.) 1988;8 (2):217-221 [PubMed]
  • Liver regeneration Hepato-gastroenterology 1988;35 (6):309-312 [PubMed]
  • Long-term follow-up of antiviral combination therapy in chronic hepatitis B American journal of medicine 1988;85 (2A):150-154 [PubMed]

1987

  • Antivirale combinatietherapie bij chronische hepatitis B Nederlands tijdschrift voor geneeskunde 1987;131 (28):1221-1225 [PubMed]
  • Correlation between electroencephalographic and biochemical indices in acute hepatic encephalopathy in rats Journal of hepatology 1987;4 (3):299-306 [PubMed]
  • Immunocytochemical study of the hepatic innervation in the rat after partial hepatectomy Histochemical journal 1987;19 (6-7):327-332 [PubMed]
  • Segmental auxiliary liver transplantation in dogs: a search for an ideal graft--illusion or reality? European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 1987;19 (5):265-275 [PubMed]

1986

  • Brain 31P NMR spectroscopy in the conscious rat Journal of neuroscience methods 1986;16 (2):151-161 [PubMed]
  • Effects of nimodipine on EEG and 31P-NMR spectra during and after incomplete forebrain ischemia in the rat European journal of pharmacology 1986;125 (3):429-435 [PubMed]

1985

  • Sarcoidosis and chronic intrahepatic cholestasis Netherlands journal of medicine 1985;28 (10):470-476 [PubMed]

1984

  • Crosslinked agarose encapsulated sorbents resistant to steam sterilization. Preparation and mechanical properties Journal of biomedical materials research 1984;18 (1):1-13 [PubMed]

1983

  • A computerised EEG-analyzing system for small laboratory animals Neuropsychobiology 1983;9 (2-3):159-162 [PubMed]
  • Problems in treating experimentally induced acute hepatic failure by hemoperfusion or cross circulation Hepatology (Baltimore, Md.) 1983;3 (5):696-700 [PubMed]
  • Quantitative analysis of EEG power spectra in experimental hepatic encephalopathy Neuropsychobiology 1983;9 (4):235-243 [PubMed]

1982

  • Coating membranes for a sorbent-based artificial liver: adsorption characteristics Artificial organs 1982;6 (3):280-287 [PubMed]

1981

  • Activated charcoal and ammonium production Lancet 1981;2 (8247):633-634 [PubMed]
  • Metabolic studies of erythropoietin (Ep): I. A reliable micro assay method for Ep in rat plasma using fetal mouse liver cells (FMLC) Experimental hematology 1981;9 (7):788-795 [PubMed]
  • Metabolic studies on erythropoietin (EP): II. The role of liver and kidney in the metabolism of Ep Experimental hematology 1981;9 (7):796-803 [PubMed]

1980

  • De behandeling van acute leverinsufficiëntie Nederlands tijdschrift voor geneeskunde 1980;124 (26):1052-1057 [PubMed]

1979

  • Inhibition of mitochondrial electron transfer in rats by ethanethiol and methanethiol Clinical science (London, England 1979;56 (2):147-156 [PubMed]
  • In vitro adsorption of possible aetiological factors of hepatic encephalopathy International journal of artificial organs 1979;2 (6):284-288 [PubMed]
  • Treatment of acute hepatic encephalopathy Netherlands journal of medicine 1979;22 (6):203-209 [PubMed]

1977

  • Een op penicilline reagerende vorm van hepatitis Nederlands tijdschrift voor geneeskunde 1977;121 (47):1888-1890 [PubMed]

1975

  • Primary biliary cirrhosis in sisters Netherlands journal of medicine 1975;18 (5):170-175 [PubMed]

1971

  • Correlation between histological and biochemical parameters of isolated perfused rat liver Virchows Archiv. B, Cell pathology including molecular pathology 1971;8 (3):243-251 [PubMed]

1970

  • Nitrogen metabolism in the perfused rat liver BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1970;222 (1):119-134 [PubMed]

1969

  • Stoicheiometry of oxidative phosphorylation with tetramethyl-p-phenylenediamine in rat-liver mitochondria BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1969;180 (1):204-206 [PubMed]