N.N. van der Wel PhD publications

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Publications PhD N.N. van der Wel

Positions
Assistant Professor, Support Staff
Main activities
Education, Research
Specialisation
Head Electron Microscopy Center Amsterdam
Focus of research

Focus of research
The research questions in the lab focuses on the understanding of Mycobacterium tuberculosis infections. This bacterium is responsible for one of the biggest killers causing the deadly disease tuberculosis. The vaccine currently used to prevent M.tuberculosis infections is M. bovis BCG. This live vaccine was developed almost 1 century ago and has not been improved ever since. We collaborate with several groups worldwide (Germany, France, Spain, Swiss, USA, South Africa) to improve this vaccine and understand the biology of tuberculosis infection. The subcellular localization of the pathogenic bacteria within cultured cells and in vivo is an important aspect (van der Wel et al., Cell 2007; Abdallah et al JI 2008; Abdallah et al., JI, 2011; Houben et al., Cell Microbiol. 2012; Weerdenburg et al., Cell Microbiol. 2012; Stoop et al; Cell Microbiol. 2013) and subject of our ongoing research. In addition, we discovered that the outermost layer of mycobacteria consists of a labile structure that contains several secreted products, involved in the immune responses of pathogenic bacteria (Sani et al 2010, Ates 2016). Currently we are investigating the mechanism of capsular stability and generation, as this is the first encounter of the vaccine BCG with the host. The projects serves both fundamental innovative research and has a clear application, in the vaccine manufacturing.

Electron Microscopy

At the Core facility Cellular Imaging, several different microscopy techniques are made available for the AMC-staff, and affiliated researchers (http://www.cellularimaging.nl). Since March 2014 Dr. Nicole van der Wel was appointed head Electron Microscopy. With a group of 4 technicians (Daisy Picavet, Henk van der Veen, Anita Grootemaat and Edwin Scholl) we assist researchers from the AMC and partners with performing Electron Microscopy. We give advice on the techniques needed, support performing and interpretation of the experiments.

November 2015 we opened the Electron Microscopy Centre Amsterdam (EMCA http://www.cellularimaging.nl/electron-microscopy/). The EMCA is a collaboration between several Amsterdam life science research institutes, including the Vumc, AMC, NKI, ACTA and NIN, and is housed at Core facility Cellular Imaging within the department of Cell Biology&Histology at the AMC. At the EMCA the operators and researchers from the different universities and institutes work on the various TEM and SEM microscopes and have shared work-discussions. The shared equipment is paid for by the involved partners as well as by various other academic and industrial users. As such we collaborate with most Amsterdam and various (inter)national research groups and have created an EM knowledge centre in Amsterdam. We have long standing expertise in transmission electron microscopy (TEM), scanning electron microscopy (SEM), but also apply new developments such as combined light electron microscopy (CLEM), tomography, immunoEM, and Cryo-EM.

Amsterdam UMC Research Institutes
AMC departments
All publications

2021

  • Wenzel Michaela, Celik Gulsoy Ilkay N., Gao Yongqiang, Teng Zihao, Willemse Joost, Middelkamp Martijn, van Rosmalen Mariska G. M., Larsen Per W. B., van der Wel Nicole N., Wuite Gijs J. L., Roos Wouter H., Hamoen Leendert W. Control of septum thickness by the curvature of sepf polymers Proceedings of the National Academy of Sciences of the United States of America 2021;118 (2) [PubMed]

2020

  • Tu Zhiwei, R Abhyankar Wishwas, N Swarge Bhagyashree, van der Wel Nicole, Kramer Gertjan, Brul Stanley, J de Koning Leo Artificial Sporulation Induction (ASI) by kinA Overexpression Affects the Proteomes and Properties of Bacillus subtilis Spores International journal of molecular sciences 2020;21 (12):1-18 [PubMed]
  • Meijer Bartolomeus J., Giugliano Francesca P., Baan Bart, van der Meer Jonathan H. M., Meisner Sander, van Roest Manon, Koelink Pim J., de Boer Ruben J., Jones Nic, Breitwieser Wolfgang, van der Wel Nicole N., Wildenberg Manon E., van den Brink Gijs R., Heijmans Jarom, Muncan Vanesa ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair Cellular and molecular gastroenterology and hepatology 2020;10 (1):23-42 [PubMed]
  • Liu Yasmine J., McIntyre Rebecca L., Janssens Georges E., Williams Evan G., Lan Jiayi, van Weeghel Michel, Schomakers Bauke, van der Veen Henk, van der Wel Nicole N., Yao Pallas, Mair William B., Aebersold Ruedi, MacInnes Alyson W., Houtkooper Riekelt H. Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30 Journal of cell biology 2020;219 (6) [PubMed]
  • Tan Josephine Mathilde Elisabeth, van der Stoel Miesje Maxime, van den Berg Marlene, van Loon Nienke Marlies, Moeton Martina, Scholl Edwin, van der Wel Nicole Neeltje, Kovačević Igor, Hordijk Peter Lodewijk, Loregger Anke, Huveneers Stephan, Zelcer Noam The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting Cell reports 2020;32 (5) [PubMed]
  • Schurink Bernadette, Roos Eva, Radonic Teodora, Barbe Ellis, Bouman Catherine S C, de Boer Hans H, de Bree Godelieve J, Bulle Esther B, Aronica Eleonora M, Florquin Sandrine, Fronczek Judith, Heunks Leo M A, de Jong Menno D, Guo Lihui, du Long Romy, Lutter Rene, Molenaar Pam C G, Neefjes-Borst E Andra, Niessen Hans W M, van Noesel Carel J M, Roelofs Joris J T H, Snijder Eric J, Soer Eline C, Verheij Joanne, Vlaar Alexander P J, Vos Wim, van der Wel Nicole N, van der Wal Allard C, van der Valk Paul, Bugiani Marianna Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study The Lancet. Microbe 2020;1 (7):e290-e299 [PubMed]

2019

  • Sabogal Piñeros Yanaika S., Bal Suzanne M., Dijkhuis Annemiek, Majoor Christof J., Dierdorp Barbara S., Dekker Tamara, Hoefsmit Esmée P., Bonta Peter I., Picavet Daisy, van der Wel Nicole N., Koenderman Leo, Sterk Peter J., Ravanetti Lara, Lutter René Eosinophils capture viruses, a capacity that is defective in asthma Allergy 2019 [PubMed]
  • van der Wijk Anne-Eva, Wisniewska-Kruk Joanna, Vogels Ilse M. C., van Veen Henk A., Ip Wing Fung, van der Wel Nicole N., van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg Expression patterns of endothelial permeability pathways in the development of the blood-retinal barrier in mice FASEB journal 2019;33 (4):5320-5333 [PubMed]
  • van der Wijk Anne-Eva, Lachkar Nadia, de Vos Judith, Grootemaat Anita E., van der Wel Nicole N., Hordijk Peter L., Bakker Erik N. T. P., vanBavel Ed Extravasation of Microspheres in a Rat Model of Silent Brain Infarcts Stroke; a journal of cerebral circulation 2019;50 (6):1590-1594 [PubMed]
  • Steenhuis Maurice, Abdallah Abdallah M., de Munnik Sabrina M., Kuhne Sebastiaan, Sterk Geert-Jan, van den Berg van Saparoea Bart, Westerhausen Sibel, Wagner Samuel, van der Wel Nicole N., Wijtmans Maikel, van Ulsen Peter, Jong Wouter S. P., Luirink Joen Inhibition of autotransporter biogenesis by small molecules Molecular microbiology 2019;112 (1):81-98 [PubMed]
  • Berendse Kevin, Boek Maxim, Gijbels Marion, van der Wel Nicole N., Klouwer Femke C., van den Bergh-Weerman Marius A., Shinde Abhijit Babaji, Ofman Rob, Poll-The Bwee Tien, Houten Sander M., Baes Myriam, Wanders Ronald J. A., Waterham Hans R. Liver disease predominates in a mouse model for mild human Zellweger spectrum disorder BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2019;1865 (10):2774-2787 [PubMed]
  • Fergusson Joannah R., Morgan Michael D., Bruchard Melanie, Huitema Leonie, Heesters Balthasar A., van Unen Vincent, van Hamburg Jan Piet, van der Wel Nicole N., Picavet Daisy, Koning Frits, Tas Sander W., Anderson Mark S., Marioni John C., Holländer Georg A., Spits Hergen Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens Frontiers in immunology 2019;9:2902 [PubMed]
  • Buter Jeffrey, Cheng Tan-Yun, Ghanem Marwan, Grootemaat Anita E., Raman Sahadevan, Feng Xinxin, Plantijn Ashmir R., Ennis Thomas, Wang Joyce, Cotton Rachel N., Layre Emilie, Ramnarine Alexandrea K., Mayfield Jacob A., Young David C., Jezek Martinot Amanda, Siddiqi Noman, Wakabayashi Shoko, Botella Helene, Calderon Roger, Murray Megan, Ehrt Sabine, Snider Barry B., Reed Michael B., Oldfield Eric, Tan Shumin, Rubin Eric J., Behr Marcel A., van der Wel Nicole N., Minnaard Adriaan J., Moody D. Branch Mycobacterium tuberculosis releases an antacid that remodels phagosomes Nature chemical biology 2019;15 (9):889-899 [PubMed]
  • Beldman Thijs J., Malinova Tsveta S., Desclos Emilie, Grootemaat Anita E., Misiak Aresh L. S., van der Velden Saskia, van Roomen Cindy P. A. A., Beckers Linda, van Veen Henk A., Krawczyk Przemyslaw M., Hoebe Ron A., Sluimer Judith C., Neele Annette E., de Winther Menno P. J., van der Wel Nicole N., Lutgens Esther, Mulder Willem J. M., Huveneers Stephan, Kluza Ewelina Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy ACS nano 2019;13 (12):13759-13774 [PubMed]

2018

  • Yu Y., Gool E., Berckmans R. J., Coumans F. A. W., Barendrecht A. D., Maas C., van der Wel N. N., Altevogt P., Sturk A., Nieuwland R. Extracellular vesicles from human saliva promote hemostasis by delivering coagulant tissue factor to activated platelets Journal of thrombosis and haemostasis 2018;16 (6):1153-1163 [PubMed]
  • Scutigliani Enzo M., Scholl Edwin R., Grootemaat Anita E., Khanal Sadhana, Kochan Jakub A., Krawczyk Przemek M., Reits Eric A., Garzan Atefeh, Ngo Huy X., Green Keith D., Garneau-Tsodikova Sylvie, Ruijter Jan M., van Veen Henk A., van der Wel Nicole N. Interfering with DNA decondensation as a strategy against mycobacteria Frontiers in microbiology 2018;9 (SEP) [PubMed]
  • van Leeuwen Lisanne M., Boot Maikel, Kuijl Coen, Picavet Daisy I., van Stempvoort Gunny, van der Pol Susanne M. A., de Vries Helga E., van der Wel Nicole N., van der Kuip Martijn, van Furth A. Marceline, van der Sar Astrid M., Bitter Wilbert Mycobacteria employ two different mechanisms to cross the blood–brain barrier Cellular microbiology 2018;20 (9) [PubMed]
  • Claushuis Theodora A. M., de Stoppelaar Sacha F., de Vos Alex F., Grootemaat Anita E., van der Wel Nicole N., Roelofs Joris J. T. H., Ware Jerry, van't Veer Cornelis, van der Poll Tom Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis Arteriosclerosis, thrombosis, and vascular biology 2018;38 (8):1772-1784 [PubMed]
  • Claushuis Theodora A. M., van der Donk Lieve E. H., Luitse Anna L., van Veen Henk A., van der Wel Nicole N., van Vught Lonneke A., Roelofs Joris J. T. H., de Boer Onno J., Lankelma Jacqueline M., Boon Louis, de Vos Alex F., van't Veer Cornelis, van der Poll Tom Role of peptidylarginine deiminase 4 in neutrophil extracellular trap formation and host defense during klebsiella pneumoniae-induced pneumonia-derived sepsis Journal of immunology (Baltimore, Md. 2018;201 (4):1241-1252 [PubMed]
  • Michailidou Iliana, Jongejan Aldo, Vreijling Jeroen P, Georgakopoulou Theodosia, de Wissel Marit B, Wolterman Ruud A, Ruizendaal Patrick, Klar-Mohamad Ngaisah, Grootemaat Anita E, Picavet Daisy I, Kumar Vinod, van Kooten Cees, Woodruff Trent M, Morgan B Paul, van der Wel Nicole N, Ramaglia Valeria, Fluiter Kees, Baas Frank Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis Acta neuropathologica communications 2018;6 (1):36 [PubMed]
  • Palao Teresa, Medzikovic Lejla, Rippe Catarina, Wanga Shaynah, Al-Mardini Claudia, van Weert Angela, de Vos Judith, van der Wel Nicole N., van Veen Henk A., van Bavel Ed T., Swärd Karl, de Waard Vivian, Bakker Erik N. TP Thrombospondin-4 mediates cardiovascular remodelling in angiotensin II-induced hypertension Cardiovascular pathology 2018;35:12-19 [PubMed]

2017

  • Maat Douwe S., Biggs Tristan, Evans Claire, van Bleijswijk Judith D. L., van der Wel Nicole N., Dutilh Bas E., Brussaard Corina P. D. Characterization and Temperature Dependence of Arctic Micromonas polaris Viruses Viruses 2017;9 (6):134 [PubMed]
  • Beldman Thijs J., Senders Max L., Alaarg Amr, Pérez-Medina Carlos, Tang Jun, Zhao Yiming, Fay Francois, Deichmöller Jacqueline, Born Benjamin, Desclos Emilie, van der Wel Nicole N., Hoebe Ron A., Kohen Fortune, Kartvelishvily Elena, Neeman Michal, Reiner Thomas, Calcagno Claudia, Fayad Zahi A., de Winther Menno P. J., Lutgens Esther, Mulder Willem J. M., Kluza Ewelina Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis ACS nano 2017;11 (6):5785-5799 [PubMed]
  • Gao Yuanqing, Vidal-Itriago Andrés, Kalsbeek Martin J., Layritz Clarita, García-Cáceres Cristina, Tom Robby Zachariah, Eichmann Thomas O., Vaz Frédéric M., Houtkooper Riekelt H., van der Wel Nicole, Verhoeven Arthur J., Yan Jie, Kalsbeek Andries, Eckel Robert H., Hofmann Susanna M., Yi Chun-Xia Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity Cell reports 2017;20 (13):3034-3042 [PubMed]
  • Bedussi Beatrice, van der Wel Nicole N., de Vos Judith, van Veen Henk, Siebes Maria, VanBavel Ed, Bakker Erik N. T. P. Paravascular channels, cisterns, and the subarachnoid space in the rat brain: A single compartment with preferential pathways Journal of cerebral blood flow and metabolism 2017;37 (4):1374-1385 [PubMed]
  • van Zon Maaike, de Punder Karin, van der Sar Astrid, Brosch Roland, Pando Rogelio Hernandez, Grootemaat Anita, Tigchelaar-Gutter Wikky, van der Wel Nicole Subcellular localization of M. tuberculosis in vivo and effect of the adaptive immunity Ultrastructural pathology 2017;41 (1):133 [PubMed]

2016

  • Zheng Linli, Abhyankar Wishwas, Ouwerling Natasja, Dekker Henk L., van Veen Henk, van der Wel Nicole N., Roseboom Winfried, de Koning Leo J., Brul Stanley, de Koster Chris G. Bacillus subtilis Spore Inner Membrane Proteome Journal of proteome research 2016;15 (2):585-594 [PubMed]
  • Potze L., Di Franco S., Grandela C., Pras-Raves M. L., Picavet D. I., van Veen H. A., van Lenthe H., Mullauer F. B., van der Wel N. N., Luyf A., van Kampen A. H. C., Kemp S., Everts V., Kessler J. H., Vaz F. M., Medema J. P. Betulinic acid induces a novel cell death pathway that depends on cardiolipin modification Oncogene 2016;35 (4):427-437 [PubMed]
  • Ribeiro Carla M. S., Sarrami-Forooshani Ramin, Setiawan Laurentia C., Zijlstra-Willems Esther M., van Hamme John L., Tigchelaar Wikky, van der Wel Nicole N., Kootstra Neeltje A., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets Nature 2016;540 (7633):448-452 [PubMed]
  • Ates Louis S., van der Woude Aniek D., Bestebroer Jovanka, van Stempvoort Gunny, Musters René J. P., Garcia-Vallejo Juan J., Picavet Daisy I., Weerd Robert van de, Maletta Massimiliano, Kuijl Coenraad P., van der Wel Nicole N., Bitter Wilbert The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10 PLoS pathogens 2016;12 (6):e1005696 [PubMed]
  • Abhyankar Wishwas R., Kamphorst Kiki, Swarge Bhagyashree N., van Veen Henk, van der Wel Nicole N., Brul Stanley, de Koster Chris G., de Koning Leo J. The Influence of Sporulation Conditions on the Spore Coat Protein Composition of Bacillus subtilis Spores Frontiers in microbiology 2016;7:1636 [PubMed]
  • van der Spek Anne H., Bloise Flavia F., Tigchelaar Wikky, Dentice Monica, Salvatore Domenico, van der Wel Nicole N., Fliers Eric, Boelen Anita The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils Endocrinology 2016;157 (8):3293-3305 [PubMed]

2014

  • Jong Wouter S. P., Daleke-Schermerhorn Maria H., Vikström David, ten Hagen-Jongman Corinne M., de Punder Karin, van der Wel Nicole N., van de Sandt Carolien E., Rimmelzwaan Guus F., Follmann Frank, Agger Else Marie, Andersen Peter, de Gier Jan-Willem, Luirink Joen An autotransporter display platform for the development of multivalent recombinant bacterial vector vaccines Microbial cell factories 2014;13:162 [PubMed]
  • Daleke-Schermerhorn Maria H., Felix Tristan, Soprova Zora, ten Hagen-Jongman Corinne M., Vikström David, Majlessi Laleh, Beskers Joep, Follmann Frank, de Punder Karin, van der Wel Nicole N., Baumgarten Thomas, Pham Thang V., Piersma Sander R., Jiménez Connie R., van Ulsen Peter, de Gier Jan-Willem, Leclerc Claude, Jong Wouter S. P., Luirink Joen Decoration of outer membrane vesicles with multiple antigens by using an autotransporter approach Applied and environmental microbiology 2014;80 (18):5854-5865 [PubMed]

2013

  • van der Woude Aniek D., Mahendran Kozhinjampara R., Ummels Roy, Piersma Sander R., Pham Thang V., Jiménez Connie R., de Punder Karin, van der Wel Nicole N., Winterhalter Mathias, Luirink Joen, Bitter Wilbert, Houben Edith N. G. Differential detergent extraction of mycobacterium marinum cell envelope proteins identifies an extensively modified threonine-rich outer membrane protein with channel activity Journal of bacteriology 2013;195 (9):2050-2059 [PubMed]
  • Stoop Esther J. M., Mishra Arun K., Driessen Nicole N., van Stempvoort Gunny, Bouchier Pascale, Verboom Theo, van Leeuwen Lisanne M., Sparrius Marion, Raadsen Susanne A., van Zon Maaike, van der Wel Nicole N., Besra Gurdyal S., Geurtsen Jeroen, Bitter Wilbert, Appelmelk Ben J., van der Sar Astrid M. Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity Cellular microbiology 2013;15 (12):2093-2108 [PubMed]

2012

  • Jong Wouter S. P., Soprova Zora, de Punder Karin, ten Hagen-Jongman Corinne M., Wagner Samuel, Wickström David, de Gier Jan-Willem, Andersen Peter, van der Wel Nicole N., Luirink Joen A structurally informed autotransporter platform for efficient heterologous protein secretion and display Microbial cell factories 2012;11:85 [PubMed]
  • Houben Diane, Demangel Caroline, van Ingen Jakko, Perez Jorge, Baldeón Lucy, Abdallah Abdallah M., Caleechurn Laxmee, Bottai Daria, van Zon Maaike, de Punder Karin, van der Laan Tridia, Kant Arie, Bossers-de Vries Ruth, Willemsen Peter, Bitter Wilbert, van Soolingen Dick, Brosch Roland, van der Wel Nicole, Peters Peter J. ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria Cellular microbiology 2012;14 (8):1287-1298 [PubMed]
  • Weerdenburg Eveline M., Abdallah Abdallah M., Mitra Suman, de Punder Karin, van der Wel Nicole N., Bird Steve, Appelmelk Ben J., Bitter Wilbert, van der Sar Astrid M. ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish Cellular microbiology 2012;14 (5):728-739 [PubMed]

2011

  • Daleke Maria H., Cascioferro Alessandro, de Punder Karin, Ummels Roy, Abdallah Abdallah M., van der Wel Nicole, Peters Peter J., Luirink Joen, Manganelli Riccardo, Bitter Wilbert Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway Journal of biological chemistry 2011;286 (21):19024-19034 [PubMed]
  • Abdallah Abdallah M., Bestebroer Jovanka, Savage Nigel D. L., de Punder Karin, van Zon Maaike, Wilson Louis, Korbee Cees J., van der Sar Astrid M., Ottenhoff Tom H. M., van der Wel Nicole N., Bitter Wilbert, Peters Peter J. Mycobacterial Secretion Systems ESX-1 and ESX-5 Play Distinct Roles in Host Cell Death and Inflammasome Activation Journal of immunology (Baltimore, Md. 2011;187 (9):4744-4753 [PubMed]

2010

  • Sani Musa, Houben Edith N. G., Geurtsen Jeroen, Pierson Jason, de Punder Karin, van Zon Maaike, Wever Brigitte, Piersma Sander R., Jiménez Connie R., Daffé Mamadou, Appelmelk Ben J., Bitter Wilbert, van der Wel Nicole, Peters Peter J. Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins PLoS pathogens 2010;6 (3):e1000794 [PubMed]
  • Weerdenburg Eveline M., Peters Peter J., van der Wel Nicole N. How do mycobacteria activate CD8(+) T cells? Trends in microbiology 2010;18 (1):1-10 [PubMed]

2008

  • Hava David L., van der Wel Nicole, Cohen Nadia, Dascher Christopher C., Houben Diane, León Luis, Agarwal Sandeep, Sugita Masahiko, van Zon Maaike, Kent Sally C., Shams Homayoun, Peters Peter J., Brenner Michael B. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation Proceedings of the National Academy of Sciences of the United States of America 2008;105 (32):11281-11286 [PubMed]
  • Abdallah Abdallah M., Savage Nigel D. L., van Zon Maaike, Wilson Louis, Vandenbroucke-Grauls Christina M. J. E., van der Wel Nicole N., Ottenhoff Tom H. M., Bitter Wilbert The ESX-5 Secretion System of Mycobacterium marinum Modulates the Macrophage Response Journal of immunology (Baltimore, Md. 2008;181 (10):7166-7175 [PubMed]

2007

  • van der Wel Nicole, Hava David, Houben Diane, Fluitsma Donna, van Zon Maaike, Pierson Jason, Brenner Michael, Peters Peter J. M-tuberculosis and M-leprae translocate from the phagolysosome to the cytosol in myeloid cells Cell 2007;129 (7):1287-1298 [PubMed]

2005

  • Boes Marianne, van der Wel Nicole, Peperzak Victor, Kim You-Me, Peters Peter J., Ploegh Hidde In vivo control of endosomal architecture by class II-associated invariant chain and cathepsin S European journal of immunology 2005;35 (9):2552-2562 [PubMed]
  • Touret Nicolas, Paroutis Paul, Terebiznik Mauricio, Harrison Rene E., Trombetta Sergio, Pypaert Marc, Chow Amy, Jiang Aimin, Shaw James, Yip Christopher, Moore Hsiao-Ping, van der Wel Nicole, Houben Diane, Peters Peter J., de Chastellier Chantal, Mellman Ira, Grinstein Sergio Quantitative and dynamic assessment of the contribution of the ER to phagosome formation Cell 2005;123 (1):157-170 [PubMed]
  • van der Wel Nicole N., Fluitsma Donna M., Dascher Christopher C., Brenner Michael B., Peters Peter J. Subcellular localization of mycobacteria in tissues and detection of lipid antigens in organelles using cryo-techniques for light and electron microscopy Current opinion in microbiology 2005;8 (3):323-330 [PubMed]
  • Angénieux Catherine, Fraisier Vincent, Maître Blandine, Racine Victor, van der Wel Nicole, Fricker Dominique, Proamer Fabienne, Sachse Martin, Cazenave Jean-Pierre, Peters Peter, Goud Bruno, Hanau Daniel, Sibarita Jean-Baptiste, Salamero Jean, de la Salle Henri The cellular pathway of CD1e in immature and maturing dendritic cells Traffic (Copenhagen, Denmark) 2005;6 (4):286-302 [PubMed]

2004

  • Baas Annette F., Kuipers Jeroen, van der Wel Nicole N., Batlle Eduard, Koerten Henk K., Peters Peter J., Clevers Hans C. Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD Cell 2004;116 (3):457-466 [PubMed]
  • Griparic Lorena, van der Wel Nicole N., Orozco Ian J., Peters Peter J., van der Bliek Alexander M. Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria Journal of biological chemistry 2004;279 (18):18792-18798 [PubMed]

2003

  • van der Wel Nicole N., Sugita Masahiko, Fluitsma Donna M., Cao Xaiochun, Schreibelt Gerty, Brenner Michael B., Peters Peter J. CD1 and major histocompatibility complex II molecules follow a different course during dendritic cell maturation Molecular biology of the cell 2003;14 (8):3378-3388 [PubMed]
  • Cernadas Manuela, Sugita Masahiko, van der Wel Nicole, Cao Xiaochun, Gumperz Jenny E., Maltsev Sergei, Besra Gurdyal S., Behar Samuel M., Peters Peter J., Brenner Michael B. Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development Journal of immunology (Baltimore, Md. 2003;171 (8):4149-4155 [PubMed]
  • Puertollano Rosa, van der Wel Nicole N., Greene Lois E., Eisenberg Evan, Peters Peter J., Bonifacino Juan S. Morphology and dynamics of clathrin/GGA1-coated carriers budding from the trans-Golgi network Molecular biology of the cell 2003;14 (4):1545-1557 [PubMed]
  • Bertens P., Heijne W., van der Wel N., Wellink J., van Kammen A. Studies on the C-terminus of the Cowpea mosaic virus movement protein Archives of virology 2003;148 (2):265-279 [PubMed]

2002

  • Cao Xiaochun, Sugita Masahiko, van der Wel Nicole, Lai Jean, Rogers Rick A., Peters Peter J., Brenner Michael B. CD1 molecules efficiently present antigen in immature dendritic cells and traffic independently of MHC class II during dendritic cell maturation Journal of immunology (Baltimore, Md. 2002;169 (9):4770-4777 [PubMed]

2000

  • Sugita M., van der Wel N., Rogers R. A., Peters P. J., Brenner M. B. CD1c molecules broadly survey the endocytic system Proceedings of the National Academy of Sciences of the United States of America 2000;97 (15):8445-8450 [PubMed]

1998

  • van der Wel N. N., Goldbach R. W., van Lent J. W. The movement protein and coat protein of alfalfa mosaic virus accumulate in structurally modified plasmodesmata Virology 1998;244 (2):322-329 [PubMed]

1997

  • Kasteel D. T., van der Wel N. N., Jansen K. A., Goldbach R. W., van Lent J. W. Tubule-forming capacity of the movement proteins of alfalfa mosaic virus and brome mosaic virus Journal of general virology 1997;78 (8):2089-2093 [PubMed]

1994

  • KRAAIJEVELD ALEX R., VAN DER WEL NICOLE N. Geographic variation in reproductive success of the parasitoid Asobara tabida in larvae of several Drosophila species Ecological Entomology 1994;19 (3):221-229
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