P. Barnett PhD publications

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Publications PhD P. Barnett

Position
Research Associate
Main activities
Research
Specialisation
Molecular biology / protein biochemistry
Focus of research

Expertise
Phil Barnett joined the group in 2003 as a protein biochemist. He has a wide background of expertise in biochemistry from molecular genetics to the structural characterization of proteins. During his PhD period he focused on both the biochemical and molecular characterization of a HOCl producing enzyme secreted by a fungus–protein purification, enzyme kinetics, cloning and crystal structure of first vnadium containing chloroperoxidase.
Shortly thereafter he started work as a postdoc at the AMC working on the purification, crystallization and mutational/functional analysis of the yeast peroxisomal import proteins Pex5, Pex13 and Pex14. Protein modelling and sequence analysis became a personal and even resulted in a couple of extra publications during this period.
After this period he joined a small starting spin-off company, Chromagenics, of the UvA as senior scientist/post-doc. The group was interested in identifying and isolating chromatin boundary elements and putting them to use in mammalian protein expression systems. He left this position in 2003 to start work at the Department of Anatomy and Embryology.

For better, more up-to-date than WOS, view of published articles and book chapters please check out scholar.google.nl/citations

Current Research
Current research focusses on the application of genome wide techniques (eg. ChIP-seq, RNAseq, 4C, bioinformatics) aimed at unravelling the regulation of cardiac transcriptome. Application of these techniques to investigate and provide functional information and basis to GWAS (genome wide association study) data. Central hypothesis is driven by the idea that GWAS can be used as a (rough) positional indicator for regulatory sequences. Genetic variation between individuals leads to trait differences, which may be disadvantageous, particularly when accompanied by disease. Understanding these connections (molecularly) may lead to new insights and approaches to patient care.
This postion allows me to exploit my knowledge of both protein biochemistry and higher order gene regulation, whilst at the same time working in a clinically translational environment.

Amsterdam UMC Research Institutes
AMC departments
All publications

2020

  • Buijtendijk Marieke F. J., Barnett Phil, van den Hoff Maurice J. B. Development of the human heart American journal of medical genetics. Part C, Seminars in medical genetics 2020;184 (1):7-22 [PubMed]
  • van Ouwerkerk Antoinette F., Bosada Fernanda M., Liu Jia, Zhang Juan, van Duijvenboden Karel, Chaffin Mark, Tucker Nathan R., Pijnappels Daniel, Ellinor Patrick T., Barnett Phil, de Vries Antoine A. F., Christoffels Vincent M. Identification of Functional Variant Enhancers Associated with Atrial Fibrillation Circulation research 2020;127 (2):229-243 [PubMed]
  • Mohan Rajiv A., Bosada Fernanda M., van Weerd Jan H., van Duijvenboden Karel, Wang Jianan, Mommersteeg Mathilda T. M., Hooijkaas Ingeborg B., Wakker Vincent, de Gier-de Vries Corrie, Coronel Ruben, Boink Gerard J. J., Bakkers Jeroen, Barnett Phil, Boukens Bas J., Christoffels Vincent M. T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system Proceedings of the National Academy of Sciences of the United States of America 2020;117 (31):18617-18626 [PubMed]
  • van Weerd Jan Hendrik, Mohan Rajiv A., van Duijvenboden Karel, Hooijkaas Ingeborg B., Wakker Vincent, Boukens Bastiaan J., Barnett Phil, Christoffels Vincent M. Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction eLife 2020;9:1-26 [PubMed]
  • van Weerd J. H. Transcriptional control of cardiac conduction system development and function 2020. 241p. ISBN 9789493197060. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Christoffels Vincent M.; Co-supervisor: Barnett Phil)

2019

  • Man Joyce C K, Mohan Rajiv A, Boogaard Malou van den, Hilvering Catharina R E, Jenkins Catherine, Wakker Vincent, Bianchi Valerio, Laat Wouter de, Barnett Phil, Boukens Bastiaan J, Christoffels Vincent M An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo Nature communications 2019;10 (1):4943 [PubMed]
  • Laarman Melanie D., Geeven Geert, Barnett Phil, Rinkel Gabriël J. E., de Laat Wouter, Ruigrok Ynte M., Bakkers Jeroen Chromatin Conformation Links Putative Enhancers in Intracranial Aneurysm-Associated Regions to Potential Candidate Genes Journal of the American Heart Association 2019;8 (9):e011201 [PubMed]
  • van Duijvenboden Karel, de Bakker Dennis E. M., Man Joyce C. K., Janssen Rob, Günthel Marie, Hill Matthew C., Hooijkaas Ingeborg B., van der Made Ingeborg, van der Kraak Petra H., Vink Aryan, Creemers Esther E., Martin James F., Barnett Phil, Bakkers Jeroen, Christoffels Vincent M. Conserved NPPB+ Border Zone Switches From MEF2- to AP-1-Driven Gene Program Circulation 2019;140 (10):864-879 [PubMed]
  • van den Boogaard M., van Weerd Jan Hendrik, Bawazeer Amira C., Hooijkaas Ingeborg B., van de Werken Harmen J. G., Tessadori Federico, de Laat Wouter, Barnett Phil, Bakkers Jeroen, Christoffels Vincent M. Identification and Characterization of a Transcribed Distal Enhancer Involved in Cardiac Kcnh2 Regulation Cell reports 2019;28 (10):2704-2714.e5 [PubMed]
  • van Ouwerkerk Antoinette F., Bosada Fernanda M., van Duijvenboden Karel, Hill Matthew C., Montefiori Lindsey E., Scholman Koen T., Liu Jia, de Vries Antoine A. F., Boukens Bastiaan J., Ellinor Patrick T., Goumans Marie José T. H., Efimov Igor R., Nobrega Marcelo A., Barnett Phil, Martin James F., Christoffels Vincent M. Identification of atrial fibrillation associated genes and functional non-coding variants Nature communications 2019;10 (1) [PubMed]

2018

  • Günthel Marie, Barnett Phil, Christoffels Vincent M. Development, Proliferation, and Growth of the Mammalian Heart Molecular therapy 2018;26 (7):1599-1609 [PubMed]
  • Mattiotti Andrea, Prakash Stuti, Barnett Phil, van den Hoff Maurice J. B. Follistatin-like 1 in development and human diseases Cellular and molecular life sciences 2018;75 (13):2339-2354 [PubMed]
  • Man Joyce, Barnett Phil, Christoffels Vincent M. Structure and function of the Nppa-Nppb cluster locus during heart development and disease Cellular and molecular life sciences 2018;75 (8):1435-1444 [PubMed]

2017

  • van den Boogaard Malou Transcriptional control of ion channel genes in arrhythmogenesis 2017. 247p. ISBN 9789082488722. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Christoffels V. M.; Co-supervisor: Barnett P.)
  • Wever Ron, Barnett Phil Vanadium Chloroperoxidases: The Missing Link in the Formation of Chlorinated Compounds and Chloroform in the Terrestrial Environment? Chemistry, an Asian journal 2017;12 (16):1997-2007 [PubMed]

2016

  • van der Harst Pim, van Setten Jessica, Verweij Niek, Vogler Georg, Franke Lude, Maurano Matthew T., Wang Xinchen, Mateo Leach Irene, Eijgelsheim Mark, Sotoodehnia Nona, Hayward Caroline, Sorice Rossella, Meirelles Osorio, Lyytikäinen Leo-Pekka, Polašek Ozren, Tanaka Toshiko, Arking Dan E., Ulivi Sheila, Trompet Stella, Müller-Nurasyid Martina, Smith Albert V., Dörr Marcus, Kerr Kathleen F., Magnani Jared W., del Greco M Fabiola, Zhang Weihua, Nolte Ilja M., Silva Claudia T., Padmanabhan Sandosh, Tragante Vinicius, Esko Tõnu, Abecasis Gonçalo R., Adriaens Michiel E., Andersen Karl, Barnett Phil, Bis Joshua C., Bodmer Rolf, Buckley Brendan M., Campbell Harry, Cannon Megan V., Chakravarti Aravinda, Chen Lin Y., Delitala Alessandro, Devereux Richard B., Doevendans Pieter A., Dominiczak Anna F., Ferrucci Luigi, Ford Ian, Gieger Christian, Harris Tamara B., Haugen Eric, Heinig Matthias, Hernandez Dena G., Hillege Hans L., Hirschhorn Joel N., Hofman Albert, Hubner Norbert, Hwang Shih-Jen, Iorio Annamaria, Kähönen Mika, Kellis Manolis, Kolcic Ivana, Kooner Ishminder K., Kooner Jaspal S., Kors Jan A., Lakatta Edward G., Lage Kasper, Launer Lenore J., Levy Daniel, Lundby Alicia, Macfarlane Peter W., May Dalit, Meitinger Thomas, Metspalu Andres, Nappo Stefania, Naitza Silvia, Neph Shane, Nord Alex S., Nutile Teresa, Okin Peter M., Olsen Jesper V., Oostra Ben A., Penninger Josef M., Pennacchio Len A., Pers Tune H., Perz Siegfried, Peters Annette, Pinto Yigal M., Pfeufer Arne, Pilia Maria Grazia, Pramstaller Peter P., Prins Bram P., Raitakari Olli T., Raychaudhuri Soumya, Rice Ken M., Rossin Elizabeth J., Rotter Jerome I., Schafer Sebastian, Schlessinger David, Schmidt Carsten O., Sehmi Jobanpreet, Silljé Herman H. W., Sinagra Gianfranco, Sinner Moritz F., Slowikowski Kamil, Soliman Elsayed Z., Spector Timothy D., Spiering Wilko, Stamatoyannopoulos John A., Stolk Ronald P., Strauch Konstantin, Tan Sian-Tsung, Tarasov Kirill V., Trinh Bosco, Uitterlinden Andre G., van den Boogaard Malou, van Duijn Cornelia M., van Gilst Wiek H., Viikari Jorma S., Visscher Peter M., Vitart Veronique, Völker Uwe, Waldenberger Melanie, Weichenberger Christian X., Westra Harm-Jan, Wijmenga Cisca, Wolffenbuttel Bruce H., Yang Jian, Bezzina Connie R., Munroe Patricia B., Snieder Harold, Wright Alan F., Rudan Igor, Boyer Laurie A., Asselbergs Folkert W., van Veldhuisen Dirk J., Stricker Bruno H., Psaty Bruce M., Ciullo Marina, Sanna Serena, Lehtimäki Terho, Wilson James F., Bandinelli Stefania, Alonso Alvaro, Gasparini Paolo, Jukema J. Wouter, Kääb Stefan, Gudnason Vilmundur, Felix Stephan B., Heckbert Susan R., de Boer Rudolf A., Newton-Cheh Christopher, Hicks Andrew A., Chambers John C., Jamshidi Yalda, Visel Axel, Christoffels Vincent M., Isaacs Aaron, Samani Nilesh J., de Bakker Paul I. W. 52 Genetic Loci Influencing Myocardial Mass Journal of the American College of Cardiology 2016;68 (13):1435-1448 [PubMed]
  • Verweij Niek, Mateo Leach Irene, Isaacs Aaron, Arking Dan E., Bis Joshua C., Pers Tune H., van den Berg Marten E., Lyytikäinen Leo-Pekka, Barnett Phil, Wang Xinchen, Soliman Elsayed Z., van Duijn Cornelia M., Kähönen Mika, van Veldhuisen Dirk J., Kors Jan A., Raitakari Olli T., Silva Claudia T., Lehtimäki Terho, Hillege Hans L., Hirschhorn Joel N., Boyer Laurie A., van Gilst Wiek H., Alonso Alvaro, Sotoodehnia Nona, Eijgelsheim Mark, de Boer Rudolf A., de Bakker Paul I. W., Franke Lude, van der Harst Pim Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram Human molecular genetics 2016;25 (10):2093-2103 [PubMed]
  • Yagihara Nobue, Watanabe Hiroshi, Barnett Phil, Duboscq-Bidot Laetitia, Thomas Atack C., Yang Ping, Ohno Seiko, Hasegawa Kanae, Kuwano Ryozo, Chatel Stéphanie, Redon Richard, Schott Jean-Jacques, Probst Vincent, Koopmann Tamara T., Bezzina Connie R., Wilde Arthur A. M., Nakano Yukiko, Aiba Takeshi, Miyamoto Yoshihiro, Kamakura Shiro, Darbar Dawood, Donahue Brian S., Shigemizu Daichi, Tanaka Toshihiro, Tsunoda Tatsuhiko, Suda Masayoshi, Sato Akinori, Minamino Tohru, Endo Naoto, Shimizu Wataru, Horie Minoru, Roden Dan M., Makita Naomasa Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes Journal of the American Heart Association 2016;5 (9):e003644 [PubMed]

2015

  • Barnett Phil, Postma Alex V. Genetics of congenital heart disease: Beyond half-measures Trends in cardiovascular medicine 2015;25 (4):302-304 [PubMed]

2014

  • van den Boogaard Malou, Smemo Scott, Burnicka-Turek Ozanna, Arnolds David E., van de Werken Harmen J. G., Klous Petra, McKean David, Muehlschlegel Jochen D., Moosmann Julia, Toka Okan, Yang Xinan H., Koopmann Tamara T., Adriaens Michiel E., Bezzina Connie R., de Laat Wouter, Seidman Christine, Seidman J. G., Christoffels Vincent M., Nobrega Marcelo A., Barnett Phil, Moskowitz Ivan P. A common genetic variant within SCN10A modulates cardiac SCN5A expression Journal of clinical investigation 2014;124 (4):1844-1852 [PubMed]
  • van Weerd Jan Hendrik, Badi Ileana, van den Boogaard Malou, Stefanovic Sonia, van de Werken Harmen J. G., Gomez-Velazquez Melisa, Badia-Careaga Claudio, Manzanares Miguel, de Laat Wouter, Barnett Phil, Christoffels Vincent M. A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system Circulation research 2014;115 (4):432-441 [PubMed]
  • Mohan Rajiv A., van Engelen Klaartje, Stefanovic Sonia, Barnett Phil, Ilgun Aho, Baars Marieke J. H., Bouma Berto J., Mulder Barbara J. M., Christoffels Vincent M., Postma Alex V. A mutation in the Kozak sequence of GATA4 hampers translation in a family with atrial septal defects American journal of medical genetics. Part A 2014;164AA (11):2732-2738 [PubMed]
  • van den Boogaard Malou, Barnett Phil, Christoffels Vincent M. From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning Trends in cardiovascular medicine 2014;24 (3):99-104 [PubMed]
  • Stefanovic Sonia, Barnett Phil, van Duijvenboden Karel, Weber David, Gessler Manfred, Christoffels Vincent M. GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development Nature communications 2014;5:3680 [PubMed]
  • Verweij Niek, Mateo Leach Irene, van den Boogaard Malou, van Veldhuisen Dirk J., Christoffels Vincent M., Hillege Hans L., van Gilst Wiek H., Barnett Phil, de Boer Rudolf A., van der Harst Pim Genetic determinants of P wave duration and PR segment Circulation. Cardiovascular genetics 2014;7 (4):475-481 [PubMed]
  • Marsman Roos F. J. Genetic risk factors for common and rare cardiac rhythm disorders 2014. 264p. ISBN 9789461086068. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Bezzina C. R., Wilde A. A. M.; Co-supervisors: Barnett P., Remme C. A.)
  • Baban Anwar, Postma Alex Vincent, Marini Monica, Trocchio Gianluca, Santilli Antonella, Pelegrini Monica, Sirleto Pietro, Lerone Margherita, Albanese Sonia Bernadette, Barnett Phil, Boogerd Cornelis Job, Dallapiccola Bruno, Digilio Maria Cristina, Ravazzolo Roberto, Pongiglione Giacomo Identification of TBX5 mutations in a series of 94 patients with Tetralogy of Fallot American journal of medical genetics. Part A 2014;164A (12):3100-3107 [PubMed]
  • Postma A. V., Alders M., Sylva M., Bilardo C. M., Pajkrt E., van Rijn R. R., Schulte-Merker S., Bulk S., Stefanovic S., Ilgun A., Barnett P., Mannens M. M. A. M., Moorman A. F. M., Oostra R. J., van Maarle M. C. Mutations in the T (brachyury) gene cause a novel syndrome consisting of sacral agenesis, abnormal ossification of the vertebral bodies and a persistent notochordal canal Journal of medical genetics 2014;51 (2):90-97 [PubMed]
  • de Boer Bouke A., van Duijvenboden Karel, van den Boogaard Malou, Christoffels Vincent M., Barnett Phil, Ruijter Jan M. OccuPeak: ChIP-Seq peak calling based on internal background modelling PLoS ONE 2014;9 (6):e99844 [PubMed]

2013

  • van den Boogaard M., Wong L. Y. E., Christoffels V. M., Barnett P. Acquisition of high quality DNA for massive parallel sequencing by in vivo chromatin immunoprecipitation Methods in molecular biology (Clifton, N.J.) 2013;977:53-64 [PubMed]
  • van de Meerakker Judith B. A., Christiaans Imke, Barnett Phil, Lekanne Deprez Ronald H., Ilgun Aho, Mook Olaf R. F., Mannens Marcel M. A. M., Lam Jan, Wilde Arthur A. M., Moorman Antoon F. M., Postma Alex V. A novel alpha-tropomyosin mutation associates with dilated and non-compaction cardiomyopathy and diminishes actin binding BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2013;1833 (4):833-839 [PubMed]
  • Cordell Heather J., Bentham Jamie, Topf Ana, Zelenika Diana, Heath Simon, Mamasoula Chrysovalanto, Cosgrove Catherine, Blue Gillian, Granados-Riveron Javier, Setchfield Kerry, Thornborough Chris, Breckpot Jeroen, Soemedi Rachel, Martin Ruairidh, Rahman Thahira J., Hall Darroch, van Engelen Klaartje, Moorman Antoon F. M., Zwinderman Aelko H., Barnett Phil, Koopmann Tamara T., Adriaens Michiel E., Varro Andras, George Alfred L., Dos Remedios Christobal, Bishopric Nanette H., Bezzina Connie R., O'Sullivan John, Gewillig Marc, Bu'lock Frances A., Winlaw David, Bhattacharya Shoumo, Devriendt Koen, Brook J. David, Mulder Barbara J. M., Mital Seema, Postma Alex V., Lathrop G. Mark, Farrall Martin, Goodship Judith A., Keavney Bernard D. Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16 Nature genetics 2013;45 (7):822-824 [PubMed]
  • Wong L. Y. Elaine Genomic mapping of Tbx3 interactions in the heart 2013. 187p. ISBN 9789461822376. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Moorman A. F. M., Christoffels V. M.; Co-supervisor: Barnett P.)
  • Boogerd C. J. J., Christoffels V. M., Barnett P. Nuclear recruitment assay as a tool to validate transcription factor interactions in Mammalian cells Methods in molecular biology (Clifton, N.J.) 2013;977:243-248 [PubMed]
  • Lüdtke Timo H.-W., Farin Henner F., Rudat Carsten, Schuster-Gossler Karin, Petry Marianne, Barnett Phil, Christoffels Vincent M., Kispert Andreas Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b PLoS genetics 2013;9 (1):e1003189 [PubMed]

2012

  • Wong L. Y. E., Moorman A. F., Barnett P. Basic Cardiac Development: The Heart and Its Electrical Componentsin: David Sedmera, Tobias Wang, editors. Ontogeny and Phylogeny of the Vertebrate Heart. Berlin: Springer; 2012. p. 177-206, ISBN 9781461433866
  • van den Boogaard Malou, Wong L. Y. Elaine, Tessadori Federico, Bakker Martijn L., Dreizehnter Lisa K., Wakker Vincent, Bezzina Connie R., 't Hoen Peter A. C., Bakkers Jeroen, Barnett Phil, Christoffels Vincent M. Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer Journal of clinical investigation 2012;122 (7):2519-2530 [PubMed]
  • Barnett Phil, van den Boogaard Malou, Christoffels Vincent LOCALIZED AND TEMPORAL GENE REGULATION IN HEART DEVELOPMENT Current topics in developmental biology 2012;100:171-201 [PubMed]
  • Singh Reena, Hoogaars Willem M., Barnett Phil, Grieskamp Thomas, Rana M. Sameer, Buermans Henk, Farin Henner F., Petry Marianne, Heallen Todd, Martin James F., Moorman Antoon F. M., 't Hoen Peter A. C., Kispert Andreas, Christoffels Vincent M. Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation Cellular and molecular life sciences 2012;69 (8):1377-1389 [PubMed]

2011

  • Barnett Phil, van den Hoff Maurice J. B. Cardiac regeneration: different cells same goal Medical & biological engineering & computing 2011;49 (7):723-732 [PubMed]
  • Boogerd Cornelis J. J., Dooijes Dennis, Ilgun Aho, Mathijssen Inge B., Hordijk Roel, van de Laar Ingrid M. B. H., Rump Patrick, Veenstra-Knol Hermine E., Moorman Antoon F. M., Barnett Phil, Postma Alex V. Functional analysis of novel TBX5 T-box mutations associated with Holt-Oram syndrome (vol 88, pg 130, 2010) Cardiovascular research 2011;89 (1):253
  • Boogerd C. J. J., Wong L. Y. E., van den Boogaard M., Bakker M. L., Tessadori F., Bakkers J., 't Hoen P. A. C., Moorman A. F., Christoffels V. M., Barnett P. Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43 Cellular and molecular life sciences 2011;68 (23):3949-3961 [PubMed]

2010

  • Boogerd Cornelis J. J., Moorman Antoon F. M., Barnett Phil Expression of muscle segment homeobox genes in the developing myocardium Anatomical record (Hoboken, N.J. 2010;293 (6):998-1001 [PubMed]
  • Boogerd Cornelis J. J., Dooijes Dennis, Ilgun Aho, Hordijk Roel, van de Laar Ingrid M. B. H., Rump Patrick, Veenstra-Knol Hermine E., Moorman Antoon F. M., Barnett Phil, Postma Alex V. Functional analysis of novel TBX5 T-box mutations associated with Holt-Oram syndrome Cardiovascular research 2010;88 (1):130-139 [PubMed]
  • Boogerd Cornelis J. J. Identification and characterization of novel protein-protein interactions during heart development 2010. 147p. ISBN 9789090253701. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Moorman A. F. M.; Co-supervisor: Barnett P.)

2009

  • van Wijk Bram, van den Berg Gert, Abu-Issa Radwan, Barnett Phil, van der Velden Saskia, Schmidt Martina, Ruijter Jan M., Kirby Margaret L., Moorman Antoon F. M., van den Hoff Maurice J. B. Epicardium and Myocardium Separate From a Common Precursor Pool by Crosstalk Between Bone Morphogenetic Protein- and Fibroblast Growth Factor-Signaling Pathways Circulation research 2009;105 (5):431-U71 [PubMed]
  • Pilichou Kalliopi, Remme Carol Ann, Basso Cristina, Campian Maria E., Rizzo Stefania, Barnett Phil, Scicluna Brendon P., Bauce Barbara, van den Hoff Maurice J. B., de Bakker Jacques M. T., Tan Hanno L., Valente Marialuisa, Nava Andrea, Wilde Arthur A. M., Moorman Antoon F. M., Thiene Gaetano, Bezzina Connie R. Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy Journal of experimental medicine 2009;206 (8):1787-1802 [PubMed]
  • Boogerd Cornelis J. J., Moorman Antoon F. M., Barnett Phil Protein interactions at the heart of cardiac chamber formation Annals of anatomy = Anatomischer Anzeiger 2009;191 (6):505-517 [PubMed]

2008

  • Postma Alex V., van de Meerakker Judith B. A., Mathijssen Inge B., Barnett Phil, Christoffels Vincent M., Ilgun Aho, Lam Jan, Wilde Arthur A. M., Lekanne Deprez Ronald H., Moorman Antoon F. M. A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation Circulation research 2008;102 (11):1433-1442 [PubMed]
  • Boogerd Kees-Jan, Wong L. Y. Elaine, Christoffels Vincent M., Klarenbeek Meinke, Ruijter Jan M., Moorman Antoon F. M., Barnett Phil Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43 Cardiovascular research 2008;78 (3):485-493 [PubMed]
  • Hoogaars Willem M. H., Barnett Phil, Rodriguez Mercedes, Clout Danielle E., Moorman Antoon F. M., Goding Colin R., Christoffels Vincent M. TBX3 and its splice variant TBX3 + exon 2a are functionally similar Pigment cell & melanoma research 2008;21 (3):379-387 [PubMed]

2007

  • Casini Simona, Tan Hanno L., Bhuiyan Zahurul A., Bezzina Connie R., Barnett Phil, Cerbai Elisabetta, Mugelli Alessandro, Wilde Arthur A. M., Veldkamp Marieke W. Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation Cardiovascular research 2007;76 (3):418-429 [PubMed]
  • Barnett P., Moorman A. F. M., van den Hoff M. J. B. Origins of cardiac differentiation and morphogenesisin: K. C. Wollert, L. J. Field, editors. Rebuilding the infarcted heart. London: Informa Healthcare; 2007. p. 1-12, ISBN 9780415419420
  • Barnett Philip, Moorman Antoon F. M., van den Hoff Maurice J. B. Origins of cardiac differentiation and morphogenesisin: Rebuilding the Infarcted Heart. CRC Press; 2007. p. 1-12, ISBN 9780415419246
  • Hoogaars W. M. H., Barnett P., Moorman A. F. M., Christoffels V. M. T-box factors determine cardiac design Cellular and molecular life sciences 2007;64 (6):646-660 [PubMed]
  • Hoogaars Willem M. H., Engel Angela, Brons Janynke F., Verkerk Arie O., de Lange Frederik J., Wong L. Y. Elaine, Bakker Martijn L., Clout Danielle E., Wakker Vincent, Barnett Phil, Ravesloot Jan Hindrik, Moorman Antoon F. M., Verheijck E. Etienne, Christoffels Vincent M. Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria Genes & development 2007;21 (9):1098-1112 [PubMed]

2005

  • Barnett Phil, Postma Alex V. Molecular Genetics of Holt–Oram Syndromein: N. N., editors. Encyclopedia of life sciences (eLS). Chichester: John Wiley & Sons Ltd; 2005. p. 10.1002/9780470015902.a0024329

2003

  • Kwaks Ted H. J., Barnett Phil, Hemrika Wieger, Siersma Tjalling, Sewalt Richard G. A. B., Satijn David P. E., Brons Janynke F., van Blokland Rik, Kwakman Paul, Kruckeberg Arle L., Kelder Angèle, Otte Arie P. Identification of anti-repressor elements that confer high and stable protein production in mammalian cells Nature biotechnology 2003;21 (5):553-558 [PubMed]

2002

  • Douangamath Alice, Filipp Fabian V., Klein André T. J., Barnett Phil, Zou Peijian, Voorn-Brouwer Tineke, Vega M. Cristina, Mayans Olga M., Sattler Michael, Distel Ben, Wilmanns Matthias Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain Molecular cell 2002;10 (5):1007-1017 [PubMed]

2001

  • Klein A. T., Barnett P., Bottger G., Konings D., Tabak H. F., Distel B. Recognition of peroxisomal targeting signal type 1 by the import receptor Pex5p Journal of biological chemistry 2001;276 (18):15034-15041 [PubMed]

2000

  • Barnett P., Tabak H. F., Hettema E. H. Nuclear receptors arose from pre-existing protein modules during evolution Trends in biochemical sciences 2000;25 (5):227-228 [PubMed]
  • Bottger G., Barnett P., Klein A. T., Kragt A., Tabak H. F., Distel B. Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner Molecular biology of the cell 2000;11 (11):3963-3976 [PubMed]
  • Barnett P., Bottger G., Klein A. T., Tabak H. F., Distel B. The peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction EMBO journal 2000;19 (23):6382-6391 [PubMed]

1998

  • Barnett P., Hemrika W., Dekker H. L., Muijsers A. O., Renirie R., Wever R. Isolation, characterization, and primary structure of the vanadium chloroperoxidase from the fungus Embellisia didymospora Journal of biological chemistry 1998;273 (36):23381-23387 [PubMed]

1997

  • Hemrika W., Renirie R., Dekker H. L., Barnett P., Wever R. From phosphatases to vanadium peroxidases: a similar architecture of the active site Proceedings of the National Academy of Sciences of the United States of America 1997;94 (6):2145-2149 [PubMed]
  • Barnett P., Kruitbosch D. L., Hemrika W., Dekker H. L., Wever R. The regulation of the vanadium chloroperoxidase from Curvularia inaequalis BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1997;1352 (1):73-84 [PubMed]

1995

  • Simons B. H., Barnett P., Vollenbroek E. G., Dekker H. L., Muijsers A. O., Messerschmidt A., Wever R. Primary structure and characterization of the vanadium chloroperoxidase from the fungus Curvularia inaequalis European Journal of Biochemistry / FEBS 1995;229 (2):566-574 [PubMed]
  • Vollenbroek E. G., Simons L. H., van Schijndel J. W., Barnett P., Balzar M., Dekker H., van der Linden C., Wever R. Vanadium chloroperoxidases occur widely in nature Biochemical Society transactions 1995;23 (2):267-271 [PubMed]

1994

  • Gardner M. J., Goldman N., Barnett P., Moore P. W., Rangachari K., Strath M., Whyte A., Williamson D. H., Wilson R. J. Phylogenetic analysis of the rpoB gene from the plastid-like DNA of Plasmodium falciparum Molecular and biochemical parasitology 1994;66 (2):221-231 [PubMed]
  • van Schijndel J. W., Barnett P., Roelse J., Vollenbroek E. G., Wever R. The stability and steady-state kinetics of vanadium chloroperoxidase from the fungus Curvularia inaequalis European Journal of Biochemistry / FEBS 1994;225 (1):151-157 [PubMed]
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