PhD A.F. de Vos publications

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Publications PhD A.F. de Vos

Position
Research Associate
Main activities
Education, Research
Specialisation
Biology - Immunology
Focus of research
  • Cellular and humoral innate immune responses against bacteria
  • Role of pattern recognition receptors in pneumonia
  • Toll-like receptor signal transduction

2019

  • de Porto Alexander P., Liu Zhe, de Beer Regina, Florquin Sandrine, de Boer Onno J., Hendriks Rudi W., van der Poll Tom, de Vos Alex F. Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia Molecular medicine (Cambridge, Mass.) 2019;25 (1):3 [PubMed]
  • Yang Jack, van’t Veer Cornelis, ten Brink Marieke S., de Vos Alex F., van der Poll Tom C3a signaling is not involved in eosinophil migration during experimental allergic lung inflammation in mice Allergy 2019 [PubMed]
  • Yang Jack, Ramirez Moral Ivan, van 't Veer Cornelis, de Vos Alex F., de Beer Regina, Roelofs Joris J. T. H., Morgan B. Paul, van der Poll Tom Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model Respiratory research 2019;20 (1):165 [PubMed]
  • Yang Jack, van Engelen Tjitske S. R., Haak Bastiaan W., Bonta Peter I., Majoor Christof J., van 't Veer Cornelis, de Vos Alex F., Kemper E. Marleen, Lutter René, van Mierlo Gerard, Zeerleder Sacha S., Bel Elisabeth H., van der Poll Tom Effect of C1-inhibitor in adults with mild asthma: A randomized controlled trial Allergy 2019 [PubMed]
  • Perlee Desiree, de Vos Alex F., Scicluna Brendon P., Mancheño Pablo, de la Rosa Olga, Dalemans Wilfried, Nürnberg Peter, Lombardo Eleuterio, van der Poll Tom Human Adipose-Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae Stem cells translational medicine 2019 [PubMed]
  • Hoogendijk Arie J., van Vught Lonneke A., Wiewel Maryse A., Fuhler Gwenny M., Belkasim-Bohoudi Hakima, Horn Janneke, Schultz Marcus J., Scicluna Brendon P., Peppelenbosch Maikel P., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Kinase activity is impaired in neutrophils of sepsis patients Haematologica 2019;104 (6):e233-e235 [PubMed]
  • Yang Jack, van 't Veer Cornelis, Roelofs Joris J. T. H., van Heijst Jeroen W. J., de Vos Alex F., McCrae Keith R., Revenko Alexey S., Crosby Jeff, van der Poll Tom Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model American journal of physiology. Lung cellular and molecular physiology 2019;316 (1):L187-L196 [PubMed]
  • Perlee Desiree Modulation of innate immunity during endotoxemia and gram-negative infection 2019. 212p. ISBN 9789463755115. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)
  • van der Meer Anne Jan, Ding Chao, Hoogendijk Arie Johan, de Vos Alex F., Boon Louis, Zeerleder Sacha S., van der Poll Tom Neutrophils mitigate the systemic host response during endotoxemia in mice Immunology 2019;156 (3):277-281 [PubMed]
  • de Porto Alexander P. N. A., Claushuis Theodora A. M., van der Donk Lieve E. H., de Beer Regina, de Boer Onno J., Florquin Sandrine, Roelofs Joris J. T. H., Hendriks Rudi W., van der Poll Tom, van't Veer Cornelis, de Vos Alex F. Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis Thrombosis and haemostasis 2019;119 (6):930-940 [PubMed]
  • Claushuis Theodora A. M., de Vos Alex F., Roelofs Joris J. T. H., de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Platelet-Dense Granules Worsen Pre-Infection Thrombocytopenia during Gram-Negative Pneumonia-Derived Sepsis Journal of innate immunity 2019;11 (2):168-180 [PubMed]
  • Ding Chao, Scicluna Brendon P., Stroo Ingrid, Yang Jack, Roelofs Joris J. TH, de Boer Onno J., de Vos Alex F., Nürnberg Peter, Revenko Alexey S., Crosby Jeff, van't Veer Cornelis, van der Poll Tom Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice Journal of pathology 2019 [PubMed]
  • Perlee Desirée, de Vos Alex F., Scicluna Brendon P., Maag Anja, Mancheño Pablo, de la Rosa Olga, Dalemans Wilfried, Florquin Sandrine, van't Veer Cornelis, Lombardo Eleuterio, van der Poll Tom Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice STEM CELL RESEARCH & THERAPY 2019;10 (1) [PubMed]
  • Birnie Emma, Weehuizen Tassili A. F., Lankelma Jacqueline M., de Jong Hanna K., Koh Gavin C. K. W., van Lieshout Miriam H. P., Roelofs Joris J. T. H., Budding Andries E., de Vos Alex F., van der Poll Tom, Wiersinga W. Joost Role of Toll-Like Receptor 5 (TLR5) in Experimental Melioidosis Infection and immunity 2019;87 (8) [PubMed]
  • de Porto Alexander P. N. A. The role of Bruton’s tyrosine kinase and the spleen in host defense against bacterial pathogens: Two essential gears in the immune clockwork 2019. 253p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: de Vos A. F. , van 't Veer C.)

2018

  • van Lieshout Miriam H. P., de Vos Alex F., Dessing Mark C., de Porto Alexander P. N. A., de Boer Onno J., de Beer Regina, Terpstra Sanne, Florquin Sandrine, van't Veer Cornelis, van der Poll Tom ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice European journal of immunology 2018;48 (1):66-79 [PubMed]
  • Perlee Desiree, van Vught Lonneke A., Scicluna Brendon P., Maag Anja, Lutter René, Kemper Elles M., van ‘t Veer Cornelis, Punchard Marie A., González Jesús, Richard Marie Paule, Dalemans Wilfried, Lombardo Eleuterio, de Vos Alex F., van der Poll Tom Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single-Blind, Parallel Group, Placebo Controlled Trial Stem cells (Dayton, Ohio) 2018;36 (11):1778-1788 [PubMed]
  • Lino Andreia C., Dang Van Duc, Lampropoulou Vicky, Welle Anna, Joedicke Jara, Pohar Jelka, Simon Quentin, Thalmensi Jessie, Baures Aurelia, Flühler Vinciane, Sakwa Imme, Stervbo Ulrik, Ries Stefanie, Jouneau Luc, Boudinot Pierre, Tsubata Takeshi, Adachi Takahiro, Hutloff Andreas, Dörner Thomas, Zimber-Strobl Ursula, de Vos Alex F., Dahlke Katja, Loh Gunnar, Korniotis Sarantis, Goosmann Christian, Weill Jean-Claude, Reynaud Claude-Agnès, Kaufmann Stefan H. E., Walter J. rn, Fillatreau Simon LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells Immunity 2018;49 (1):120-133.e9 [PubMed]
  • Claushuis Theodora A. M., de Stoppelaar Sacha F., de Vos Alex F., Grootemaat Anita E., van der Wel Nicole N., Roelofs Joris J. T. H., Ware Jerry, van't Veer Cornelis, van der Poll Tom Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis Arteriosclerosis, thrombosis, and vascular biology 2018;38 (8):1772-1784 [PubMed]
  • Claushuis Theodora A. M., de Vos Alex F., Nieswandt Bernard, Boon Louis, Roelofs Joris J. T. H., de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria Blood 2018;131 (8):864-876 [PubMed]
  • Claushuis Theodora A. M., van der Donk Lieve E. H., Luitse Anna L., van Veen Henk A., van der Wel Nicole N., van Vught Lonneke A., Roelofs Joris J. T. H., de Boer Onno J., Lankelma Jacqueline M., Boon Louis, de Vos Alex F., van't Veer Cornelis, van der Poll Tom Role of peptidylarginine deiminase 4 in neutrophil extracellular trap formation and host defense during klebsiella pneumoniae-induced pneumonia-derived sepsis Journal of immunology (Baltimore, Md. 2018;201 (4):1241-1252 [PubMed]
  • Claushuis Theodora A. M. The role of platelets in sepsis 2018. ISBN 9789090309743. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., de Vos A. F.)

2017

  • Lankelma Jacqueline M., Cranendonk Duncan R., Belzer Clara, de Vos Alex F., de Vos Willem M., van der Poll Tom, Wiersinga W. Joost Antibiotic-induced gut microbiota disruption during human endotoxemia: a randomised controlled study Gut 2017;66 (9):1623-1630 [PubMed]
  • Anas Adam A. Cell-specific innate immunity in lung infection and inflammation 2017. 152p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: de Vos A. F., van 't Veer C.)
  • Weehuizen Tassili A. F., Birnie Emma, Ferwerda Bart, Roelofs Joris J. T. H., de Vos Alex F., Grobusch Martin P., Wiersinga W. Joost Differences in Inflammation Patterns Induced by African and Asian Burkholderia pseudomallei Isolates in Mice American journal of tropical medicine and hygiene 2017;96 (6):1365-1369 [PubMed]
  • Anas Adam A., Claushuis Theodora A. M., Mohan Rajiv A., Christoffels Vincent M., Aidinis Vassilis, Florquin Sandrine, van't Veer Cornelis, Hou Baidong, de Vos Alex F., van der Poll Tom Epithelial Myeloid-Differentiation Factor 88 Is Dispensable during Klebsiella Pneumonia American journal of respiratory cell and molecular biology 2017;56 (5):648-656 [PubMed]
  • García-Laorden M. Isabel, Stroo Ingrid, Terpstra Sanne, Florquin Sandrine, Medema Jan Paul, van T Veer Cornelis, de Vos Alex F., van der Poll Tom Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis Mediators of inflammation 2017;2017:4137563 [PubMed]
  • Anas A. A., Yang J., Daan de Boer J., Roelofs J. J. T. H., Hou B., de Vos A. F., van der Poll T. General, but not myeloid or type II lung epithelial cell, myeloid differentiation factor 88 deficiency abrogates house dust mite induced allergic lung inflammation Clinical and experimental immunology 2017;187 (2):204-212 [PubMed]
  • Hoogendijk Arie J., Garcia-Laorden M. Isabel, van Vught Lonneke A., Wiewel Maryse A., Belkasim-Bohoudi Hakima, Duitman Janwillem, Horn Janneke, Schultz Marcus J., Scicluna Brendon P., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Sepsis Patients Display a Reduced Capacity to Activate Nuclear Factor-κB in Multiple Cell Types Critical care medicine 2017;45 (5):e524-e531 [PubMed]
  • Lankelma Jacqueline M., Birnie Emma, Weehuizen Tassili A. F., Scicluna Brendon P., Belzer Clara, Houtkooper Riekelt H., Roelofs Joris J. T. H., de Vos Alex F., van der Poll Tom, Budding Andries E., Wiersinga W. Joost The gut microbiota as a modulator of innate immunity during melioidosis PLoS neglected tropical diseases 2017;11 (4):e0005548 [PubMed]

2016

  • Lankelma Jacqueline M., Belzer Clara, Hoogendijk Arie J., de Vos Alex F., de Vos Willem M., van der Poll Tom, Wiersinga W. Joost Antibiotic-Induced Gut Microbiota Disruption Decreases TNF-alpha Release by Mononuclear Cells in Healthy Adults Clinical and translational gastroenterology 2016;7 (8):e186 [PubMed]
  • Anas Adam A., de Vos Alex F., Hoogendijk Arie J., van Lieshout Miriam H. P., van Heijst Jeroen W. J., Florquin Sandrine, Li Zihai, van 't Veer Cornelis, van der Poll Tom Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia Journal of pathology 2016;238 (1):74-84 [PubMed]
  • van den Boogaard Florry E., van Gisbergen Klaas P. J. M., Vernooy Juanita H., Medema Jan P., Roelofs Joris J. T. H., van Zoelen Marieke A. D., Endeman Henrik, Biesma Douwe H., Boon Louis, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Granzyme A impairs host defense during Streptococcus pneumoniae pneumonia American journal of physiology. Lung cellular and molecular physiology 2016;311 (2):L507-L516 [PubMed]
  • García-Laorden M. Isabel, Stroo Ingrid, Blok Dana C., Florquin Sandrine, Medema Jan Paul, de Vos Alex F., van der Poll Tom Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia Journal of innate immunity 2016;8 (3):258-268 [PubMed]
  • Anas Adam A., van Lieshout Miriam H. P., Claushuis Theodora A. M., de Vos Alex F., Florquin Sandrine, de Boer Onno J., Hou Baidong, van't Veer Cornelis, van der Poll Tom Lung epithelial MyD88 drives early pulmonary clearance of Pseudomonas aeruginosa by a flagellin dependent mechanism American journal of physiology. Lung cellular and molecular physiology 2016;311 (2):L219-L228 [PubMed]
  • van den Bossche Jan, Baardman Jeroen, Otto Natasja A., van der Velden Saskia, Neele Annette E., van den Berg Susan M., Luque-Martin Rosario, Chen Hung-Jen, Boshuizen Marieke C. S., Ahmed Mohamed, Hoeksema Marten A., de Vos Alex F., de Winther Menno P. J. Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages Cell reports 2016;17 (3):684-696 [PubMed]
  • Hamers Anouk A. J., Argmann Carmen, Moerland Perry D., Koenis Duco S., Marinković Goran, Sokolović Milka, de Vos Alex F., de Vries Carlie J. M., van Tiel Claudia M. Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance BMC genomics 2016;17 (1):162 [PubMed]
  • Achouiti Ahmed, de Vos Alex F., van 't Veer Cornelis, Florquin Sandrine, Tanck Michael W., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom, van Zoelen Marieke A. D. Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia PLoS ONE 2016;11 (1):e0141000 [PubMed]
  • Schuijt Tim J., Lankelma Jacqueline M., Scicluna Brendon P., de Sousa E Melo Felipe, Roelofs Joris J. T. H., de Boer J. Daan, Hoogendijk Arjan J., de Beer Regina, de Vos Alex, Belzer Clara, de Vos Willem M., van der Poll Tom, Wiersinga W. Joost The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia Gut 2016;65 (4):575-583 [PubMed]
  • Huson Michaëla A. M., Hoogendijk Arie J., de Vos Alex F., Grobusch Martin P., van der Poll Tom The impact of HIV infection on blood leukocyte responsiveness to bacterial stimulation in asymptomatic patients and patients with bloodstream infection Journal of the International AIDS Society 2016;19 (1):20759 [PubMed]
  • Weehuizen Tassili A. F., Lankelma Jacqueline M., de Jong Hanna K., de Boer Onno J., Roelofs Joris J. T. H., Day Nicholas P., Gram Hermann, de Vos Alex F., Wiersinga W. Joost Therapeutic Administration of a Monoclonal Anti-Il-1β Antibody Protects Against Experimental Melioidosis Shock (Augusta, Ga.) 2016;46 (5):566-574 [PubMed]
  • van der Meer Anne Jan, Achouiti Achmed, van der Ende Arie, Soussan Aicha A., Florquin Sandrine, de Vos Alex, Zeerleder Sacha S., van der Poll Tom Toll-like receptor 9 enhances bacterial clearance and limits lung consolidation in murine pneumonia caused by methicillin resistant Staphylococcus aureus Molecular medicine (Cambridge, Mass.) 2016;22:292-299 [PubMed]
  • Weehuizen Tassili A. F., Hommes Tijmen J., Lankelma Jacqueline M., de Jong Hanna K., Roelofs Joris J. T. H., de Vos Alex F., Colonna Marco, van der Poll Tom, Wiersinga W. Joost Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis PLoS neglected tropical diseases 2016;10 (6):e0004747 [PubMed]

2015

  • de Boer J. Daan, Berger Marieke, Majoor Christof J., Kager Liesbeth M., Meijers Joost C. M., Terpstra Sanne, Nieuwland Rienk, Boing Anita N., Lutter René, Wouters Diana, van Mierlo Gerard J., Zeerleder Sacha S., Bel Elisabeth H., van't Veer Cornelis, de Vos Alex F., van der Zee Jaring S., van der Poll Tom Activated protein C inhibits neutrophil migration in allergic asthma: a randomised trial European respiratory journal 2015;46 (6):1636-1644 [PubMed]
  • van Lieshout Miriam Hanneke Petra Cell-specific pattern recognition receptor signaling in antibacterial defense 2015. 264p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., de Vos A. F.)
  • Weehuizen Tassili A. F., Prior Joann L., van der Vaart Thomas W., Ngugi Sarah A., Nepogodiev Sergey A., Field Robert A., Kager Liesbeth M., van 't Veer Cornelis, de Vos Alex F., Wiersinga W. Joost Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models PLoS ONE 2015;10 (12):e0145397 [PubMed]
  • Achouiti Ahmed Endogenous danger signals in infectious diseases 2015. 272p. ISBN 9789461697240. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., de Vos A. F.)
  • de Jong Hanna K., Achouiti Ahmed, Koh Gavin C. K. W., Parry Christopher M., Baker Stephen, Faiz Mohammed Abul, van Dissel Jaap T., Vollaard Albert M., van Leeuwen Ester M. M., Roelofs Joris J. T. H., de Vos Alex F., Roth Johannes, van der Poll Tom, Vogl Thomas, Wiersinga Willem Joost Expression and function of S100A8/A9 (calprotectin) in human typhoid fever and the murine Salmonella model PLoS neglected tropical diseases 2015;9 (4):e0003663 [PubMed]
  • Blok Dana C., Kager Liesbeth M., Hoogendijk Arie J., Lede Ivar O., Rahman Wahid, Afroz Rumana, Bresser Paul, van der Zee Jaring S., Ghose Aniruddha, Visser Caroline E., de Jong Menno D., Zahed Abu Shahed Md, Husain Md Anwar, Alam Khan Mashrequl, Barua Pravat Chandra, Hassan Mahtabuddin, Hossain Ahmed, Tayab Md Abu, Lutter Rene, Day Nick, Dondorp Arjen M., de Vos Alex F., van 't Veer Cornelis, van der Poll Tom Expression of inhibitory regulators of innate immunity in patients with active tuberculosis BMC infectious diseases 2015;15 (1):98 [PubMed]
  • Garcia-Laorden M. Isabel, Blok Dana C., Kager Liesbeth M., Hoogendijk Arie J., van Mierlo Gerard J., Lede Ivar O., Rahman Wahid, Afroz Rumana, Ghose Aniruddha, Visser Caroline E., Md Zahed Abu Shahed, Husain Md Anwar, Alam Khan Mashrequl, Chandra Barua Pravat, Hassan Mahtabuddin, Hossain Ahmed, Tayab Md Abu, Day Nick, Dondorp Arjen M., de Vos Alex F., van der Poll Tom Increased intra- and extracellular granzyme expression in patients with tuberculosis Tuberculosis (Edinburgh, Scotland) 2015;95 (5):575-580 [PubMed]
  • Achouiti Ahmed, Vogl Thomas, van der Meer Anne J., Stroo Ingrid, Florquin Sandrine, de Boer Onno J., Roth Johannes, Zeerleder Sacha, van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia European respiratory journal 2015;46 (2):464-473 [PubMed]
  • Hommes Tijmen J., van Lieshout Miriam H., van 't Veer Cornelis, Florquin Sandrine, Bootsma Hester J., Hermans Peter W., de Vos Alex F., van der Poll Tom Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia PLoS ONE 2015;10 (12):e0145138 [PubMed]
  • Hommes Tijmen J., Dessing Mark C., Veer Cornelis van 't, Florquin Sandrine, Colonna Marco, de Vos Alex F., van der Poll Tom Role of Triggering Receptor Expressed on Myeloid Cells-1/3 in Klebsiella-Derived Pneumosepsis American journal of respiratory cell and molecular biology 2015;53 (5):647-655 [PubMed]
  • Hoogendijk Arie J., Blok Dana C., Garcia Laorden M. Isabel, Kager Liesbeth M., Lede Ivar O., Rahman Wahid, Afroz Rumana, Bresser Paul, van der Zee Jaring S., Ghose Aniruddha, Visser Caroline E., de Jong Menno D., Zahed Abu Shahed Md, Husain Md Anwar, Alam Khan Mashrequl, Barua Pravat Chandra, Hassan Mahtabuddin, Hossain Ahmed, Tayab Md Abu, Lutter Rene, Day Nick, Dondorp Arjen M., van't Veer Cornelis, de Vos Alex F., van der Poll Tom Soluble and cell-associated triggering receptor expressed on myeloid cells-1 and -2 in patients with pulmonary tuberculosis Journal of infection 2015;71 (6):706-709 [PubMed]
  • de Vos Alex F., Dessing Mark C., Lammers Adriana J. J., de Porto Alexander P. N. A., Florquin Sandrine, de Boer Onno J., de Beer Regina, Terpstra Sanne, Bootsma Hester J., Hermans Peter W., van 't Veer Cornelis, van der Poll Tom The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice PLoS ONE 2015;10 (2):e0118181 [PubMed]
  • Achouiti Ahmed, van't Veer Cornelis, de Vos Alex F., van der Poll Tom The receptor for advanced glycation end products promotes bacterial growth at distant body sites in Staphylococcus aureus skin infection Microbes and infection / Institut Pasteur 2015;17 (9):622-627 [PubMed]
  • van Lieshout Miriam H. P., Florquin Sandrine, Vanʼt Veer Cornelis, de Vos Alex F., van der Poll Tom TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Mediates Antibacterial Defense during Gram-Negative Pneumonia by Inducing Interferon-x03B3 Journal of innate immunity 2015;7 (6):637-646 [PubMed]
  • Blok Dana Christa Toll-like receptor and associated regulators in pneumonia and sepsis 2015. 164p. ISBN 9789461696823. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)
  • Hommes Tijmen Johannes TREM receptors in infection and inflammation 2015. 182p. ISBN 9789461697660. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)

2014

  • Hommes Tijmen J., Hoogendijk Arie J., Dessing Mark C., van't Veer Cornelis, Florquin Sandrine, de Vos Alex F., van der Poll Tom DNAX-Activating Protein of 12 kDa Impairs Host Defense in Pneumococcal Pneumonia Critical care medicine 2014;42 (12):E783-E790 [PubMed]
  • van Lieshout Miriam H. P., Anas Adam A., Florquin Sandrine, Hou Baidong, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis PLoS pathogens 2014;10 (9):e1004368 [PubMed]
  • de Boer J. Daan, Yang Jack, van den Boogaard Florry E., Hoogendijk Arie J., de Beer Regina, van der Zee Jaring S., Roelofs Joris J. T. H., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Mast cell-deficient kit mice develop house dust mite-induced lung inflammation despite impaired eosinophil recruitment Journal of innate immunity 2014;6 (2):219-226 [PubMed]
  • Achouiti Ahmed, Vogl Thomas, Endeman Henrik, Mortensen Brittany L., Laterre Pierre-Francois, Wittebole Xavier, van Zoelen Marieke A. D., Zhang Yaofang, Hoogerwerf Jacobien J., Florquin Sandrine, Schultz Marcus J., Grutters Jan C., Biesma Douwe H., Roth Johannes, Skaar Eric P., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia Thorax 2014;69 (11):1034-1042 [PubMed]
  • de Boer J. Daan, van't Veer Cornelis, Stroo Ingrid, van der Meer Anne J., de Vos Alex F., van der Zee Jaring S., Roelofs Joris J. T. H., van der Poll Tom Protease-activated receptor-2 deficient mice have reduced house dust mite-evoked allergic lung inflammation Innate immunity 2014;20 (6):618-625 [PubMed]
  • Blok Dana C., van Lieshout Miriam H. P., Hoogendijk Arie J., Florquin Sandrine, de Boer Onno J., Garlanda Cecilia, Mantovani Alberto, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae Journal of innate immunity 2014;6 (4):542-552 [PubMed]
  • Kager Liesbeth M., de Vos Alex F., Roelofs Joris J. T. H., van der Loos Chris M., de Boer Onno J., van't Veer Cornelis, Conway Edward M., van der Poll Tom The thrombomodulin lectin-like domain does not change host responses to tuberculosis Thrombosis and haemostasis 2014;111 (2):345-353 [PubMed]
  • Hommes Tijmen J., Hoogendijk Arie J., Dessing Mark C., van't Veer Cornelis, Florquin Sandrine, Colonna Marco, de Vos Alex F., van der Poll Tom Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia Journal of pathology 2014;233 (4):357-367 [PubMed]

2013

  • den Hertog Alice L., de Vos Alex F., Klatser Paul R., Anthony Richard M. Early specific host response associated with starting effective tuberculosis treatment in an infection controlled placebo controlled mouse study PLoS ONE 2013;8 (2):e57997 [PubMed]
  • Achouiti Ahmed, van der Meer Anne Jan, Florquin Sandrine, Yang Huan, Tracey Kevin J., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia Critical care (London, England) 2013;17 (6):R296 [PubMed]
  • Blok Dana C., van der Sluijs Koenraad F., Florquin Sandrine, de Boer Onno J., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia PLoS ONE 2013;8 (3):e58191 [PubMed]
  • Achouiti Ahmed, de Vos Alex F., de Beer Regina, Florquin Sandrine, van 't Veer Cornelis, van der Poll Tom Limited role of the receptor for advanced glycation end products during Streptococcus pneumoniae bacteremia Journal of innate immunity 2013;5 (6):603-612 [PubMed]
  • Daan de Boer J., Roelofs Joris J. T. H., de Vos Alex F., de Beer Regina, Schouten Marcel, Hommes Tijmen J., Hoogendijk Arie J., de Boer Onno J., Stroo Ingrid, van der Zee Jaring S., Veer Cornelis Van't, van der Poll Tom Lipopolysaccharide inhibits Th2 lung inflammation induced by house dust mite allergens in mice American journal of respiratory cell and molecular biology 2013;48 (3):382-389 [PubMed]
  • Blok Dana C., de Vos Alex F., Florquin Sandrine, van der Poll Tom Role of interleukin 1 receptor like 1 (ST2) in gram-negative and gram-positive sepsis in mice Shock (Augusta, Ga.) 2013;40 (4):290-296 [PubMed]
  • Kager Liesbeth M., Roelofs Joris J. T. H., de Vos Alex F., Wieland Catharina W., Schouten Marcel, Meijers Joost C. M., Isermann Berend, van't Veer Cornelis, Esmon Charles T., van der Poll Tom The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis Thrombosis and haemostasis 2013;109 (4):726-737 [PubMed]

2012

  • van Lieshout Miriam H. P., Blok Dana C., Wieland Catharina W., de Vos Alex F., van 't Veer Cornelis, van der Poll Tom Differential Roles of MyD88 and TRIF in Hematopoietic and Resident Cells During Murine Gram-Negative Pneumonia Journal of infectious diseases 2012;206 (9):1415-1423 [PubMed]
  • Reynier Frederic, de Vos Alex F., Hoogerwerf Jacobien J., Bresser Paul, van der Zee Jaring S., Paye Malick, Pachot Alexandre, Mougin Bruno, van der Poll Tom Gene Expression Profiles in Alveolar Macrophages Induced by Lipopolysaccharide in Humans Molecular medicine (Cambridge, Mass.) 2012;18 (9):1303-1311 [PubMed]
  • Hoogerwerf Jacobien J., van der Windt Gerritje J. W., Blok Dana C., Hoogendijk Arie J., de Vos Alex F., van 't Veer Cornelis, Florquin Sandrine, Kobayashi Koichi S., Flavell Richard A., van der Poll Tom Interleukin-1 Receptor-Associated Kinase M-Deficient Mice Demonstrate an Improved Host Defense during Gram-negative Pneumonia Molecular medicine (Cambridge, Mass.) 2012;18 (7):1067-1075 [PubMed]
  • van der Windt Gerritje J. W., Blok Dana C., Hoogerwerf Jacobien J., Lammers Adriana J. J., de Vos Alex F., van't Veer Cornelis, Florquin Sandrine, Kobayashi Koichi S., Flavell Richard A., van der Poll Tom Interleukin 1 Receptor-Associated Kinase M Impairs Host Defense During Pneumococcal Pneumonia Journal of infectious diseases 2012;205 (12):1849-1857 [PubMed]
  • Achouiti Ahmed, Vogl Thomas, Urban Constantin F., Röhm Marc, Hommes Tijmen J., van Zoelen Marieke A. D., Florquin Sandrine, Roth Johannes, van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis PLoS pathogens 2012;8 (10):e1002987 [PubMed]

2011

  • van Westerloo David J., Choi Goda, Löwenberg Ester C., Truijen Jasper, de Vos Alex F., Endert Erik, Meijers Joost C. M., Zhou Lu, Pereira Manuel Pfl, Queiroz Karla C. S., Diks Sander H., Levi Marcel, Peppelenbosch Maikel P., van der Poll Tom Acute Stress Elicited by Bungee Jumping Suppresses Human Innate Immunity Molecular medicine (Cambridge, Mass.) 2011;17 (3-4):180-188 [PubMed]
  • Veninga Henrike, Hoek Robert M., de Vos Alex F., de Bruin Alex M., An Feng-Qi, van der Poll Tom, van Lier René A. W., Medof M. Edward, Hamann Jörg A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense PLoS ONE 2011;6 (10):e24431 [PubMed]
  • van 't Veer Cornelis, van den Pangaart Petra S., Kruijswijk Daniëlle, Florquin Sandrine, de Vos Alex F., van der Poll Tom Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli Journal of biological chemistry 2011;286 (42):36603-36618 [PubMed]
  • Molenaar Rosalie, Knippenberg Marlene, Goverse Gera, Olivier Brenda J., de Vos Alex F., O'Toole Tom, Mebius Reina E. Expression of retinaldehyde dehydrogenase enzymes in mucosal dendritic cells and gut-draining lymph node stromal cells is controlled by dietary vitamin A Journal of immunology (Baltimore, Md. 2011;186 (4):1934-1942 [PubMed]
  • Hoogerwerf Jacobien J., Leendertse Masja, Wieland Catharina W., de Vos Alex F., de Boer J. Daan, Florquin Sandrine, van der Poll Tom Loss of Suppression of Tumorigenicity 2 (ST2) Gene Reverses Sepsis-induced Inhibition of Lung Host Defense in Mice American journal of respiratory and critical care medicine 2011;183 (7):932-940 [PubMed]
  • van der Windt Gerritje J. W., Hoogendijk Arie J., Schouten Marcel, Hommes Tijmen J., de Vos Alex F., Florquin Sandrine, van der Poll Tom Osteopontin Impairs Host Defense During Pneumococcal Pneumonia Journal of infectious diseases 2011;203 (12):1850-1858 [PubMed]
  • van der Windt Gerritje J. W., Hoogendijk Arie J., de Vos Alex F., Kerver Marjolein E., Florquin Sandrine, van der Poll Tom The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia Laboratory investigation; a journal of technical methods and pathology 2011;91 (4):588-597 [PubMed]

2010

  • van der Windt Gerritje J. W., Florquin Sandrine, de Vos Alex F., van't Veer Cornelis, Queiroz Karla C. S., Liang Jiurong, Jiang Dianhua, Noble Paul W., van der Poll Tom CD44 Deficiency Is Associated with Increased Bacterial Clearance but Enhanced Lung Inflammation During Gram-Negative Pneumonia American journal of pathology 2010;177 (5):2483-2494 [PubMed]
  • Hoogerwerf Jacobien J., van Zoelen Marieke A., Wiersinga W. Joost, van 't Veer Cornelis, de Vos Alex F., de Boer Anita, Schultz Marcus J., Hooibrink Berend, de Jonge Evert, van der Poll Tom Gene Expression Profiling of Apoptosis Regulators in Patients with Sepsis Journal of innate immunity 2010;2 (5):461-468 [PubMed]
  • Hoogerwerf Jacobien J. Immunotolerance during bacterial pneumonia and sepsis 2010. 171p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: de Vos A. F., van 't Veer C.)
  • van der Windt G. J. W., Hoogerwerf J. J., de Vos A. F., Florquin S., van der Poll T. Osteopontin promotes host defense during Klebsiella pneumoniae-induced pneumonia European respiratory journal 2010;36 (6):1337-1345 [PubMed]
  • Hoogerwerf Jacobien J., de Vos Alex F., van't Veer Cornelis, Bresser Paul, de Boer Anita, Tanck Michael W. T., Draing Christian, van der Zee Jaring S., van der Poll Tom Priming of Alveolar Macrophages upon Instillation of Lipopolysaccharide in the Human Lung American journal of respiratory cell and molecular biology 2010;42 (3):349-356 [PubMed]
  • Anas A. A., Wiersinga W. J., de Vos A. F., van der Poll T. Recent insights into the pathogenesis of bacterial sepsis Netherlands journal of medicine 2010;68 (4):147-152 [PubMed]
  • Anas Adam A., Hovius Joppe W. R., van 't Veer Cornelis, van der Poll Tom, de Vos Alex F. Role of CD14 in a Mouse Model of Acute Lung Inflammation Induced by Different Lipopolysaccharide Chemotypes PLoS ONE 2010;5 (4):e10183 [PubMed]
  • Anas Adam, van der Poll Tom, de Vos Alex F. Role of CD14 in lung inflammation and infection Critical care (London, England) 2010;14 (2):209 [PubMed]
  • Anas Adam, van der Poll Tom, de Vos Alex F. Role of CD14 in lung inflammation and infection Yearbook of intensive care and emergency medicine 2010;2010:129-140
  • Leendertse Masja, Willems Rob J. L., Flierman Roelof, de Vos Alex F., Bonten Marc J. M., van der Poll Tom The Complement System Facilitates Clearance of Enterococcus faecium during Murine Peritonitis Journal of infectious diseases 2010;201 (4):544-552 [PubMed]
  • van der Windt Gerritje J. W. The role of CD44 and osteopontin in infection and imflammation 2010. 224p. ISBN 9789090251981. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)
  • Wiersinga W. Joost, Kager Liesbeth M., Hovius Joppe W. R., van der Windt Gerritje J. W., de Vos Alex F., Meijers Joost C. M., Roelofs Joris J., Dondorp Arjen, Levi Marcel, Day Nicholas P., Peacock Sharon J., van der Poll Tom Urokinase Receptor Is Necessary for Bacterial Defense against Pneumonia-Derived Septic Melioidosis by Facilitating Phagocytosis Journal of immunology (Baltimore, Md. 2010;184 (6):3079-3086 [PubMed]

2009

  • Hoogerwerf Jacobien J., de Vos Alex F., Levi Marcel, Bresser Paul, van der Zee Jaring S., Draing Christian, von Aulock Sonja, van der Poll Tom Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide Critical care medicine 2009;37 (2):619-625 [PubMed]
  • de Vos Alex F., Pater Jennie M., van den Pangaart Petra S., de Kruif Martijn D., van 't Veer Cornelis, van der Poll Tom In Vivo Lipopolysaccharide Exposure of Human Blood Leukocytes Induces Cross-Tolerance to Multiple TLR Ligands Journal of immunology (Baltimore, Md. 2009;183 (1):533-542 [PubMed]
  • van Zoelen Marieke A. D., Schmidt Ann-Marie, Florquin Sandrine, Meijers Joost C., de Beer Regina, de Vos Alex F., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom Receptor for Advanced Glycation End Products Facilitates Host Defense during Escherichia coli-Induced Abdominal Sepsis in Mice Journal of infectious diseases 2009;200 (5):765-773 [PubMed]
  • Dessing Mark C., Hirst Robert A., de Vos Alex F., van der Poll Tom Role of Toll-Like Receptors 2 and 4 in Pulmonary Inflammation and Injury Induced by Pneumolysin in Mice PLoS ONE 2009;4 (11):e7993 [PubMed]
  • van Zoelen Marieke A. D., Schouten Marcel, de Vos Alex F., Florquin Sandrine, Meijers Joost C. M., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom The Receptor for Advanced Glycation End Products Impairs Host Defense in Pneumococcal Pneumonia Journal of immunology (Baltimore, Md. 2009;182 (7):4349-4356 [PubMed]
  • Stegenga Michiel E., Florquin Sandrine, de Vos Alex F., van der Poll Tom The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice Critical care medicine 2009;37 (2):614-618 [PubMed]
  • Hovius Joppe W. R., Bijlsma Maarten F., van der Windt Gerritje J. W., Wiersinga W. Joost, Boukens Bastiaan J. D., Coumou Jeroen, Oei Anneke, de Beer Regina, de Vos Alex F., van 't Veer Cornelis, van Dam Alje P., Wang Penghua, Fikrig Erol, Levi Marcel M., Roelofs Joris J. T. H., van der Poll Tom The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi PLoS pathogens 2009;5 (5):e1000447 [PubMed]
  • Lagler Heimo, Sharif Omar, Haslinger Isabella, Matt Ulrich, Stich Karin, Furtner Tanja, Doninger Bianca, Schmid Katharina, Gattringer Rainer, de Vos Alex F., Knapp Sylvia TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia Journal of immunology (Baltimore, Md. 2009;183 (3):2027-2036 [PubMed]

2008

  • Veninga Henrike, Becker Susann, Hoek Robert M., Wobus Manja, Wandel Elke, van der Kaa Jos, van der Valk Martin, de Vos Alex F., Haase Hannelore, Owens Bronwyn, van der Poll Tom, van Lier René A. W., Verbeek J. Sjef, Aust Gabriela, Hamann Jörg Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration Journal of immunology (Baltimore, Md. 2008;181 (9):6574-6583 [PubMed]
  • Wiersinga W. Joost, de Vos Alex F., Wieland Catharina W., Leendertse Masja, Roelofs Joris J. T. H., van der Poll Tom CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice Journal of infectious diseases 2008;198 (9):1388-1397 [PubMed]
  • Stegenga M. E., van der Crabben S. N., Dessing M. C., Pater J. M., van den Pangaart P. S., de Vos A. F., Tanck M. W., Roos D., Sauerwein H. P., van der Poll T. Effect of acute hyperglycaemia and/or hyperinsulinaemia on proinflammatory gene expression, cytokine production and neutrophil function in humans Diabetic medicine 2008;25 (2):157-164 [PubMed]
  • Wiersinga W. Joost, de Vos Alex F., de Beer Regina, Wieland Catharina W., Roelofs Joris J. T. H., Woods Donald E., van der Poll Tom Inflammation patterns induced by different Burkholderia species in mice Cellular microbiology 2008;10 (1):81-87 [PubMed]
  • Hoogerwerf Jacobien J., de Vos Alex F., Bresser Paul, van der Zee Jaring S., Pater Jennie M., de Boer Anita, Tanck Michael, Lundell Daniel L., Her-Jenh Chung, Draing Christian, von Aulock Sonja, van der Poll Tom Lung inflammation induced by lipoteichoic acid or lipopolysaccharide in humans American journal of respiratory and critical care medicine 2008;178 (1):34-41 [PubMed]
  • van Zoelen Marieke A. D., Florquin Sandrine, Meijers Joost C. M., de Beer Regina, de Vos Alex F., de Boer Onno J., van der Poll Tom Platelet-activating factor receptor contributes to host defense against Pseudomonas aeruginosa pneumonia but is not essential for the accompanying inflammatory and procoagulant response Journal of immunology (Baltimore, Md. 2008;180 (5):3357-3365 [PubMed]
  • van Westerloo David J., Rauws Erik A., Hommes Daan, de Vos Alex F., van der Poll Tom, Powers Barbara L., Fockens Paul, Dijkgraaf Marcel G. W., Bruno Marco J. Pre-ERCP infusion of semapimod, a mitogen-activated protein kinases inhibitor, lowers post-ERCP hyperamylasemia but not pancreatitis incidence Gastrointestinal endoscopy 2008;68 (2):246-254 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., van den Pangaart Petra S., Wiersinga W. Joost, de Vos Alex F., Florquin Sandrine, Bonten Marc J. M., van der Poll Tom TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis Journal of immunology (Baltimore, Md. 2008;180 (7):4865-4874 [PubMed]

2007

  • Dessing Mark C., Knapp Sylvia, Florquin Sandrine, de Vos Alex F., van der Poll Tom CD14 facilitates invasive respiratory tract infection by Streptococcus pneumoniae American journal of respiratory and critical care medicine 2007;175 (6):604-611 [PubMed]
  • van 't Veer Cornelis, van den Pangaart Petra S., van Zoelen Marieke A. D., de Kruif Martijn, Birjmohun Rakesh S., Stroes Eric S., de Vos Alex F., van der Poll Tom Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model Journal of immunology (Baltimore, Md. 2007;179 (10):7110-7120 [PubMed]
  • van Zoelen Marieke A. D., de Vos Alex F., Larosa Gregory J., Draing Christian, von Aulock Sonja, van der Poll Tom Intrapulmonary delivery of ethyl pyruvate attenuates lipopolysaccharide- and lipoteichoic acid-induced lung inflammation in vivo Shock (Augusta, Ga.) 2007;28 (5):570-575 [PubMed]
  • Giebelen Ida A. J., van Westerloo David J., Larosa Gregory J., de Vos Alex F., van der Poll Tom Local stimulation of alpha 7 cholinergic receptors inhibits LPS-induced TNF-alpha release in the mouse lung Shock (Augusta, Ga.) 2007;28 (6):700-703 [PubMed]
  • de Kruif Martijn D., Lemaire Lucienne C., Giebelen Ida A., van Zoelen Marieke A. D., Pater Jennie M., van den Pangaart Petra S., Groot Angelique P., de Vos Alex F., Elliott Peter J., Meijers Joost C. M., Levi Marcel, van der Poll Tom Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia Journal of immunology (Baltimore, Md. 2007;178 (3):1845-1851 [PubMed]
  • Maris Nico A., de Vos Alex F., Bresser Paul, van der Zee Jaring S., Jansen Henk M., Levi Marcel, van der Poll Tom Salmeterol enhances pulmonary fibrinolysis in healthy volunteers Critical care medicine 2007;35 (1):57-63 [PubMed]
  • Giebelen Ida A. J., van Westerloo David J., Larosa Gregory J., de Vos Alex F., van der Poll Tom Stimulation of alpha 7 cholinergic receptors inhibits lipopolysaccharide-induced neutrophil recruitment by a tumor necrosis factor alpha-independent mechanism Shock (Augusta, Ga.) 2007;27 (4):443-447 [PubMed]
  • van Westerloo D. J. The inflammatory response in critical illness 2007. 211p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll Tom; Co-supervisors: Bruno M. J., de Vos Alex F.)
  • Wiersinga W. Joost, Wieland Catharina W., Dessing Mark C., Chantratita Narisara, Cheng Allen C., Limmathurotsakul Direk, Chierakul Wirongrong, Leendertse Masja, Florquin Sandrine, de Vos Alex F., White Nicholas, Dondorp Arjen M., Day Nicholas P., Peacock Sharon J., van der Poll Tom Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis) PLoS medicine 2007;4 (7):e248-1280 [PubMed]
  • Dessing Mark C. Toll-like receptors and innate immunity in pneumonia 2007. 191p. ISBN 9789090218649. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll Tom; Co-supervisor: de Vos Alex F.)

2006

  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Pater Jennie M., Lijnen H. Roger, Carmeliet Peter, van 't Veer Cornelis, van der Poll Tom Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice Journal of immunology (Baltimore, Md. 2006;177 (2):1189-1196 [PubMed]
  • Heesen Michael, Renckens Rosemarijn, de Vos Alex F., Kunz Dagmar, van der Poll Tom Human endotoxemia induces down-regulation of monocyte CC chemokine receptor 2 Clinical and vaccine immunology 2006;13 (1):156-159 [PubMed]
  • Stegenga Michiel E., van der Crabben Saskia N., Levi Marcel, de Vos Alex F., Tanck Michael W., Sauerwein Hans P., van der Poll Tom Hyperglycemia stimulates coagulation, whereas hyperinsulinemia impairs fibrinolysis in healthy humans Diabetes 2006;55 (6):1807-1812 [PubMed]
  • Maris Nico A., Florquin Sandrine, van't Veer Cornelis, de Vos Alex F., Buurman Wim, Jansen Henk M., van der Poll Tom Inhalation of beta 2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract Respiratory research 2006;7:57 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Lijnen H. Roger, van't Veer Cornelis, van der Poll Tom Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis Journal of immunology (Baltimore, Md. 2006;176 (6):3735-3741 [PubMed]
  • Maris N. A. Modulation of lung inflammation by salmeterol, a beta2 adrenergic receptor agonist 2006. 179p. ISBN 9789090198903. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Jansen H. M.; Co-supervisor: de Vos A. F.)
  • Dessing Mark C., de Vos Alex F., Florquin Sandrine, van der Poll Tom Monocyte chemoattractant protein 1 does not contribute to protective immunity against pneumococcal pneumonia Infection and immunity 2006;74 (12):7021-7023 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Knapp Sylvia, de Vos Alex F., Florquin Sandrine, van der Poll Tom The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii Pneumonia Journal of infectious diseases 2006;193 (2):187-195 [PubMed]
  • Maris N. A., Dessing M. C., de Vos A. F., Bresser P., van der Zee J. S., Jansen H. M., Spek C. A., van der Poll T. Toll-like receptor mRNA levels in alveolar macrophages after inhalation of endotoxin European respiratory journal 2006;28 (3):622-626 [PubMed]
  • van Westerloo D. J., Giebelen I. A. J., Meijers J. C. M., Daalhuisen J., de Vos A. F., Levi M. [=Marcel M.], van der Poll T. Vagus nerve stimulation inhibits activation of coagulation and fibrinolysis during endotoxemia in rats Journal of thrombosis and haemostasis 2006;4 (9):1997-2002 [PubMed]

2005

  • Maris Nico A., de Vos Alex F., Bresser Paul, van der Zee Jaring S., Meijers Joost C., Lijnen H. Roger, Levi Marcel, Jansen Henk M., van der Poll Tom Activation of coagulation and inhibition of fibrinolysis in the lung after inhalation of lipopolysaccharide by healthy volunteers Thrombosis and haemostasis 2005;93 (6):1036-1040 [PubMed]
  • Maris Nico A., de Vos Alex F., Dessing Mark C., Spek C. Arnold, Lutter Rene, Jansen Henk M., van der Zee Jaring S., Bresser Paul, van der Poll Tom Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers American journal of respiratory and critical care medicine 2005;172 (7):878-884 [PubMed]
  • van Westerloo David J., Knapp Sylvia, van't Veer Cornelis, Buurman Wim A., de Vos Alex F., Florquin Sandrine, van der Poll Tom Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia Critical care medicine 2005;33 (8):1770-1778 [PubMed]
  • Rijneveld Anita W., de Vos Alex F., Florquin Sandrine, Verbeek J. Sjef, van der Poll Tom CD11b limits bacterial outgrowth and dissemination during murine pneumococcal pneumonia Journal of infectious diseases 2005;191 (10):1755-1760 [PubMed]
  • van Westerloo David J., Giebelen Ilona A. J., Florquin Sandrine, Daalhuisen Joost, Bruno Marco J., de Vos Alex F., Tracey Kevin J., van der Poll Tom The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis Journal of infectious diseases 2005;191 (12):2138-2148 [PubMed]
  • van Westerloo David J., Florquin Sandrine, de Boer Anita M., Daalhuisen Joost, de Vos Alex F., Bruno Marco J., van der Poll Tom Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice American journal of pathology 2005;166 (3):721-728 [PubMed]
  • van Westerloo David J., Weijer Sebastiaan, Bruno Marco J., de Vos Alex F., van't Veer Cornelis, van der Poll Tom Toll-like receptor 4 deficiency and acute pancreatitis act similarly in reducing host defense during murine Escherichia coli peritonitis Critical care medicine 2005;33 (5):1036-1043 [PubMed]

2004

  • van Westerloo David J., Schultz Marcus J., Bruno Marco J., de Vos Alex F., Florquin Sandrine, van der Poll Tom Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis Critical care medicine 2004;32 (10):1997-2001 [PubMed]
  • de Vos Alex F., Melief Marie-José, van Riel Debby, Boon Louis, van Eijk Marco, de Boer Mark, Laman Jon D. Antagonist anti-human CD40 antibody inhibits germinal center formation in cynomolgus monkeys European journal of immunology 2004;34 (12):3446-3455 [PubMed]
  • Knapp Sylvia, Gibot Sébastien, de Vos Alex, Versteeg Henri H., Colonna Marco, van der Poll Tom Cutting edge: Expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia Journal of immunology (Baltimore, Md. 2004;173 (12):7131-7134 [PubMed]
  • Renckens Rosemarijn, Weijer Sebastiaan, de Vos Alex F., Pater Jennie M., Meijers Joost C., Hack C. Erik, Levi Marcel, van der Poll Tom Inhibition of plasmin activity by tranexamic acid does not influence inflammatory pathways during human endotoxemia Arteriosclerosis, thrombosis, and vascular biology 2004;24 (3):483-488 [PubMed]
  • Wieland Catharina W., Knapp Sylvia, Florquin Sandrine, de Vos Alex F., Takeda Kiyoshi, Akira Shizuo, Golenbock Douglas T., Verbon Annelies, van der Poll Tom Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2 American journal of respiratory and critical care medicine 2004;170 (12):1367-1374 [PubMed]
  • Maris Nico A., van der Sluijs Koenraad F., Florquin Sandrine, de Vos Alex F., Pater Jennie M., Jansen Henk M., van der Poll Tom Salmeterol, a beta(2)-receptor agonist, attenuates lipopolysaccharide-induced lung inflammation in mice American journal of physiology. Lung cellular and molecular physiology 2004;286 (6):L1122-L1128 [PubMed]

2003

  • Eldering Eric, Spek C. Arnold, Aberson Hella L., Grummels Annette, Derks Ingrid A., de Vos Alex F., McElgunn Cathal J., Schouten Jan P. Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways Nucleic acids research 2003;31 (23):e153 [PubMed]
  • Weijer Sebastiaan, Sewnath Miguel E., de Vos Alex F., Florquin Sandrine, van der Sluis Koen, Gouma Dirk J., Takeda Kiyoshi, Akira Shizuo, van der Poll Tom Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis Infection and immunity 2003;71 (10):5488-5497 [PubMed]
  • Knapp Sylvia, de Vos Alex F., Florquin Sandrine, Golenbock Douglas T., van der Poll Tom Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice Infection and immunity 2003;71 (12):6747-6753 [PubMed]

2002

  • Visser Lizette, de Vos Alex F., Hamann Jörg, Melief Marie-José, van Meurs Marjan, van Lier René A. W., Laman Jon D., Hintzen Rogier Q. Expression of the EGF-TM7 receptor CD97 and its ligand CD55 (DAF) in multiple sclerosis Journal of neuroimmunology 2002;132 (1-2):156-163 [PubMed]
  • de Vos Alex F., van Meurs Marjan, Brok Herbert P., Boven Leonie A., Hintzen Rogier Q., van der Valk Paul, Ravid Rivka, Rensing Susanne, Boon Louis, 't Hart Bert A., Laman Jon D. Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs Journal of immunology (Baltimore, Md. 2002;169 (10):5415-5423 [PubMed]

2001

  • Holtkamp G. M., Kijlstra A., Peek R., de Vos A. F. Retinal pigment epithelium-immune system interactions: cytokine production and cytokine-induced changes Progress in retinal and eye research 2001;20 (1):29-48 [PubMed]

1999

  • Analysis of the secretion pattern of monocyte chemotactic protein-1 (MCP-1) and transforming growth factor-beta 2 (TGF-beta2) by human retinal pigment epithelial cells Clinical and experimental immunology 1999;118 (1):35-40 [PubMed]
  • Experimental autoimmune keratitis induced in rats by anti-cornea T-cell lines Investigative ophthalmology & visual science 1999;40 (10):2191-2198 [PubMed]

1998

  • Polarized secretion of IL-6 and IL-8 by human retinal pigment epithelial cells Clinical and experimental immunology 1998;112 (1):34-43 [PubMed]

1996

  • Cytokine mRNA expression during experimental corneal allograft rejection Experimental eye research 1996;63 (4):453-461 [PubMed]
  • Macrophages in the retina of normal Lewis rats and their dynamics after injection of lipopolysaccharide Investigative ophthalmology & visual science 1996;37 (1):77-85 [PubMed]

1995

  • Inhibiting interleukin-1 and tumor necrosis factor-alpha does not reduce induction of plasminogen activator inhibitor type-1 by endotoxin in rats in vivo Blood 1995;85 (1):115-120 [PubMed]
  • Systemic anti-tumor necrosis factor antibody treatment exacerbates endotoxin-induced uveitis in the rat Experimental eye research 1995;61 (6):667-675 [PubMed]
  • Tumour necrosis factor-induced uveitis in the Lewis rat is associated with intraocular interleukin 6 production Experimental eye research 1995;60 (2):199-207 [PubMed]

1994

  • Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat Investigative ophthalmology & visual science 1994;35 (11):3873-3883 [PubMed]
  • Kinetics of intraocular tumor necrosis factor and interleukin-6 in endotoxin-induced uveitis in the rat Investigative ophthalmology & visual science 1994;35 (3):1100-1106 [PubMed]

1992

  • Cytokines and uveitis, a review Current eye research 1992;11 (6):581-597 [PubMed]