PhD J.H. Akkerdaas publications

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Publications PhD J.H. Akkerdaas

Position
Research Associate
Main activities
Research
Specialisation
Allergy research
Focus of research
  • Protein-chemistry and molecular biology of respiratory and food allergens: what makes an allergen an allergen?
  • Innovative approaches for in vitro and in vivo diagnosis of IgE-mediated allergy: from allergen extracts to molecular diagnostics.
  • Innovative biopharmaceutical approaches for allergen-specific immunotherapy: recombinant technology, novel adjuvants and administration routes.
  • Immuno-epidemiology of respiratory and food allergies: the role of allergen exposure, environment, diet, infections and lifestyle in the development of allergy.
  • Mouse models of allergy and asthma: how are sensitization and disease expression regulated?

 

2018

  • Warners Marijn J., Terreehorst Ingrid, van den Wijngaard René M., Akkerdaas Jaap, van Esch Betty C. A. M., van Ree Ronald, Versteeg Serge A., Smout Andreas J. P. M., Bredenoord Albert J. Abnormal Responses to Local Esophageal Food Allergen Injections in Adult Patients With Eosinophilic Esophagitis Gastroenterology 2018;154 (1):57-+ [PubMed]
  • Fu Wanyi, Gao Zhongshan, Gao Ling, Jin Jing, Liu Meiling, Sun Yuemei, Wu Shandong, Wu Lingying, Ma Hongshan, Dong Yimin, Wang Xuefeng, Gao Biyuan, Wang Huiying, Akkerdaas Jaap H., Versteeg Serge A., van Ree Ronald Identification of a 62 kDa major allergen from Artemisia pollen as a putative galactose oxidase Allergy 2018;73 (5):1041-1052 [PubMed]
  • Akkerdaas Jaap, Totis Muriel, Barnett Brian, Bell Erin, Davis Tom, Edrington Thomas, Glenn Kevin, Graser Gerson, Herman Rod, Knulst Andre, Ladics Gregory, McClain Scott, Poulsen Lars K., Ranjan Rakesh, Rascle Jean-Baptiste, Serrano Hector, Speijer Dave, Wang Rong, Pereira Mouriès Lucilia, Capt Annabelle, van Ree Ronald Protease resistance of food proteins: A mixed picture for predicting allergenicity but a useful tool for assessing exposure Clinical and translational allergy 2018;8 (1) [PubMed]

2017

  • Buhler Sofie, Akkerdaas Jaap H., A Pertinhez Thelma, van Ree Ronald, Dossena Arnaldo, Sforza Stefano, Tedeschi Tullia Development of a strategy for the total chemical synthesis of an allergenic protein: the peach LTP Pru p 3 Journal of peptide science 2017;23 (4):282-293 [PubMed]

2016

  • Gao Zhong-Shan, Zhou Xiang, Yang Zhao-Wei, Versteeg Serge A., Gao Ling, Fu Wan-Yi, Wang Hui-Ying, Zhou Jian-Ying, Akkerdaas Jaap H., van Ree Ronald IgE-binding potencies of three peach Pru p 1 isoforms Molecular nutrition & food research 2016;60 (11):2457-2466 [PubMed]
  • Gao Zhong-Shan, Ma Ying-tao, Zhou Xiang, Yang Zhao-Wei, Jia Hui-juan, Gao Ling, Wu Shan-Dong, Han Lu-yang, Yi Xue-ying, Wang Hui-Ying, Akkerdaas Jaap H., van Ree Ronald Quantification of Peach Fruit Allergen Lipid Transfer Protein by a Double Monoclonal Antibody-based Sandwich ELISA Food Analytical Methods 2016;9 (4):823-830

2015

  • Utsch L., Folisi C., Akkerdaas J. H., Logiantara A., van de Pol M. A., van der Zee J. S., Krop E. J. M., Lutter R., van Ree R., van Rijt L. S. Allergic sensitization is associated with inadequate antioxidant responses in mice and men Allergy 2015;70 (10):1246-1258 [PubMed]
  • Zuidmeer-Jongejan Laurian, Huber Hans, Swoboda Ines, Rigby Neil, Versteeg Serge A., Jensen Bettina M., Quaak Suzanne, Akkerdaas Jaap H., Blom Lars, Asturias Juan, Bindslev-Jensen Carsten, Bernardi Maria L., Clausen Michael, Ferrara Rosa, Hauer Martina, Heyse Jet, Kopp Stephan, Kowalski Marek L., Lewandowska-Polak Anna, Linhart Birgit, Maderegger Bernhard, Maillere Bernard, Mari Adriano, Martinez Alberto, Mills E. N. Clare, Neubauer Angela, Nicoletti Claudio, Papadopoulos Nikolaos G., Portoles Antonio, Ranta-Panula Ville, Santos-Magadan Sara, Schnoor Heidi J., Sigurdardottir Sigurveig T., Stahl-Skov Per, Stavroulakis George, Stegfellner Georg, Vázquez-Cortés Sonia, Witten Marianne, Stolz Frank, Poulsen Lars K., Fernandez-Rivas Montserrat, Valenta Rudolf, van Ree Ronald Development of a hypoallergenic recombinant parvalbumin for first-in-man subcutaneous immunotherapy of fish allergy International archives of allergy and immunology 2015;166 (1):41-51 [PubMed]
  • van Rhijn Bram D., Vlieg-Boerstra Berber J., Versteeg Serge A., Akkerdaas Jaap H., van Ree Ronald, Terreehorst Ingrid, Sprikkelman Aline B., Verheij Joanne, Smout Andreas J. P. M., Bredenoord Albert J. Evaluation of allergen-microarray-guided dietary intervention as treatment of eosinophilic esophagitis Journal of allergy and clinical immunology 2015;136 (4):1095-7.e3 [PubMed]

2014

  • Zuidmeer-Jongejan Laurian, Fernández-Rivas Montserrat, Winter Marcel G. T., Akkerdaas Jaap H., Summers Colin, Lebens Ans, Knulst André C., Schilte Piet, Briza Peter, Gadermaier Gabriele, van Ree Ronald Oil body-associated hazelnut allergens including oleosins are underrepresented in diagnostic extracts but associated with severe symptoms Clinical and translational allergy 2014;4 (1):4 [PubMed]
  • Burney P. G. J., Potts J., Kummeling I., Mills E. N. C., Clausen M., Dubakiene R., Barreales L., Fernandez-Perez C., Fernandez-Rivas M., Le T.-M., Knulst A. C., Kowalski M. L., Lidholm J., Ballmer-Weber B. K., Braun-Fahlander C., Mustakov T., Kralimarkova T., Popov T., Sakellariou A., Papadopoulos N. G., Versteeg S. A., Zuidmeer L., Akkerdaas J. H., Hoffmann-Sommergruber K., van Ree R. The prevalence and distribution of food sensitization in European adults Allergy 2014;69 (3):365-371 [PubMed]

2013

  • Amoah Abena S., Obeng Benedicta B., Larbi Irene A., Versteeg Serge A., Aryeetey Yvonne, Akkerdaas Jaap H., Zuidmeer Laurian, Lidholm Jonas, Fernández-Rivas Montserrat, Hartgers Franca C., Boakye Daniel A., van Ree Ronald, Yazdanbakhsh Maria Peanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivity Journal of allergy and clinical immunology 2013;132 (3):639-647 [PubMed]
  • Masthoff Laury J. N., Mattsson Lars, Zuidmeer-Jongejan Laurian, Lidholm Jonas, Andersson Kerstin, Akkerdaas Jaap H., Versteeg Serge A., Garino Cristiano, Meijer Yolanda, Kentie Petra, Versluis Astrid, den Hartog Jager Constance F., Bruijnzeel-Koomen Carla A. F. M., Knulst André C., van Ree Ronald, van Hoffen Els, Pasmans Suzanne G. M. A. Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults Journal of allergy and clinical immunology 2013;132 (2):393-399 [PubMed]

2012

  • Akkerdaas J., Finkina E. I., Balandin S. V., Santos Magadán S., Knulst A., Fernandez-Rivas M., Asero R., van Ree R., Ovchinnikova T. V. Lentil (Lens culinaris) Lipid Transfer Protein Len c 3: A Novel Legume Allergen International archives of allergy and immunology 2012;157 (1):51-57 [PubMed]

2010

  • van Zuuren E. J., Terreehorst I., Tupker R. A., Hiemstra P. S., Akkerdaas J. H. Anaphylaxis after consuming soy products in patients with birch pollinosis Allergy 2010;65 (10):1348-1349 [PubMed]

2008

  • Flinterman Annebeth E., Akkerdaas Jaap H., Knulst André C., van Ree Ronald, Pasmans Suzanne G. Hazelnut allergy: from pollen-associated mild allergy to severe anaphylactic reactions Current opinion in allergy and clinical immunology 2008;8 (3):261-265 [PubMed]
  • Flinterman Annebeth E., Akkerdaas Jaap H., den Hartog Jager Constance F., Rigby Neil M., Fernandez-Rivas Montserrat, Hoekstra Maarten O., Bruijnzeel-Koomen Carla A., Knulst André C., van Ree Ronald, Pasmans Suzanne G. Lipid transfer protein-linked hazelnut allergy in children from a non-Mediterranean birch-endemic area Journal of allergy and clinical immunology 2008;121 (2):423-428.e2 [PubMed]
  • Marsh Justin, Rigby Neil, Wellner Klaus, Reese Gerald, Knulst André, Akkerdaas Jaap, van Ree Ronald, Radauer Christian, Lovegrove Alison, Sancho Ana, Mills Clare, Vieths Stefan, Hoffmann-Sommergruber Karin, Shewry Peter R. Purification and characterisation of a panel of peanut allergens suitable for use in allergy diagnosis Molecular nutrition & food research 2008;52 (Suppl. 2):S272-S285 [PubMed]
  • Rigby Neil M., Marsh Justin, Sancho Ana I., Wellner Klaus, Akkerdaas Jaap, van Ree Ronald, Knulst Andre, Fernández-Rivas Montserrat, Brettlova Vlasta, Schilte Piet P., Summer Colin, Pumphrey Richard, Shewry Peter R., Mills E. N. Clare The purification and characterisation of allergenic hazelnut seed proteins Molecular nutrition & food research 2008;52 (Suppl. 2):S251-S261 [PubMed]

2007

  • Vassilopoulou Emilia V., Zuidmeer Laurian, Akkerdaas Jaap, Rigby Neil, Moren F. Javier, Papadopoulos Nikolaos G., Saxoni-Papageorgiou Photini, Milis Clare, van Ree Ronald Optimized techniques for the extraction of grape allergens appropriate for in vivo and in vitro testing and diagnosis Molecular nutrition & food research 2007;51 (3):360-366 [PubMed]
  • Vassilopoulou Emilia, Zuidmeer Laurian, Akkerdaas Jaap, Tassios Ioannis, Rigby Neil R., Mills E. N. Clare, van Ree Ronald, Saxoni-Papageorgiou Photini, Papadopoulos Nikolaos G. Severe immediate allergic reactions to grapes: part of a lipid transfer protein-associated clinical syndrome International archives of allergy and immunology 2007;143 (2):92-102 [PubMed]

2006

  • Flinterman Annebeth E., Hoekstra Maarten O., Meijer Yolanda, van Ree Ronald, Akkerdaas Jaap H., Bruijnzeel-Koomen Carla A., Knulst André C., Pasmans Suzanne G. Clinical reactivity to hazelnut in children: association with sensitization to birch pollen or nuts? Journal of allergy and clinical immunology 2006;118 (5):1186-1189 [PubMed]
  • Akkerdaas Jaap H., Schocker Frauke, Vieths Stefan, Versteeg Serge, Zuidmeer Laurian, Hefle Sue L., Aalberse Rob C., Richter Klaus, Ferreira Fatima, van Ree Ronald Cloning of oleosin, a putative new hazelnut allergen, using a hazelnut cDNA library Molecular nutrition & food research 2006;50 (1):18-23 [PubMed]
  • Vassilopoulou Emilia, Rigby Neil, Moreno F. Javier, Zuidmeer Laurian, Akkerdaas Jaap, Tassios Ioannis, Papadopoulos Nikos G., Saxoni-Papageorgiou Photini, van Ree Ronald, Mills Clare Effect of in vitro gastric and duodenal digestion on the allergenicity of grape lipid transfer protein Journal of allergy and clinical immunology 2006;118 (2):473-480 [PubMed]

2005

  • Akkerdaas Jaap H. Identification and quantification of hazelnut allergens 2005. 176p. ISBN 9789064642432. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Aalberse R. C.; Co-supervisor: van Ree R.)
  • Akkerdaas Jaap H., Wensing Marjolein, Asero Riccardo, Fernandez Rivas Montserrat, Rivas Montserrat Fernandez, Knulst André C., Bolhaar Suzanne, Hefle Susan L., Aalberse Rob C., van Ree Ronald IgE binding to pepsin-digested food extracts International archives of allergy and immunology 2005;138 (3):203-208 [PubMed]
  • Zuidmeer Laurian, van Leeuwen W. Astrid, Budde Ilona Kleine, Cornelissen Jessica, Bulder Ingrid, Rafalska Ilona, Besolí Noèlia Telléz, Akkerdaas Jaap H., Asero Riccardo, Fernandez Rivas Montserrat, Rivas Montserrat Fernandez, Gonzalez Mancebo Eloina, Mancebo Eloina Gonzalez, van Ree Ronald Lipid transfer proteins from fruit: cloning, expression and quantification International archives of allergy and immunology 2005;137 (4):273-281 [PubMed]
  • Gilissen Luud J. W. J., Bolhaar Suzanne T. H. P., Matos Catarina I., Rouwendal Gerard J. A., Boone Marjan J., Krens Frans A., Zuidmeer Laurian, van Leeuwen Astrid, Akkerdaas Jaap, Hoffmann-Sommergruber Karin, Knulst André C., Bosch Dirk, van de Weg W. Eric, van Ree Ronald Silencing the major apple allergen Mal d 1 by using the RNA interference approach Journal of allergy and clinical immunology 2005;115 (2):364-369 [PubMed]

2004

  • Akkerdaas Jaap H., Wensing Marjolein, Knulst André C., Stephan Oliver, Hefle Susan L., Aalberse Rob C., van Ree Ronald A novel approach for the detection of potentially hazardous pepsin stable hazelnut proteins as contaminants in chocolate-based food Journal of agricultural and food chemistry 2004;52 (25):7726-7731 [PubMed]
  • Mittag Diana, Akkerdaas Jaap, Ballmer-Weber Barbara K., Vogel Lothar, Wensing Marjolein, Becker Wolf-Meinhard, Koppelman Stef J., Knulst André C., Helbling Arthur, Hefle Susan L., van Ree Ronald, Vieths Stefan Ara h 8, a Bet v 1-homologous allergen from peanut, is a major allergen in patients with combined birch pollen and peanut allergy Journal of allergy and clinical immunology 2004;114 (6):1410-1417 [PubMed]
  • Schocker Frauke, Lüttkopf Dirk, Scheurer Stephan, Petersen Arnd, Cisteró-Bahima Anna, Enrique Ernesto, San Miguel-Moncín Mar, Akkerdaas Jaap, van Ree Ronald, Vieths Stefan, Becker Wolf-Meinhard Recombinant lipid transfer protein Cor a 8 from hazelnut: a new tool for in vitro diagnosis of potentially severe hazelnut allergy Journal of allergy and clinical immunology 2004;113 (1):141-147 [PubMed]

2003

  • Akkerdaas Jaap H., Wensing Marjolein, Knulst André C., Krebitz Monika, Breiteneder Heimo, de Vries Sacco, Penninks André H., Aalberse Rob C., Hefle Sue L., van Ree Ronald How accurate and safe is the diagnosis of hazelnut allergy by means of commercial skin prick test reagents? International archives of allergy and immunology 2003;132 (2):132-140 [PubMed]
  • Akkerdaas Jaap H., Wensing Marjolein, Knulst André C., Aalberse Rob C., Hefle Susan L., van Ree Ronald In vitro and in vivo characterization of hazelnut skin prick test extracts Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt fur Sera und Impfstoffe) zu Frankfurt a.M 2003 (94):87-95; discussion 96 [PubMed]

2002

  • Wensing Marjolein, Akkerdaas Jaap H., van Leeuwen W. Astrid, Stapel Steven O., Bruijnzeel-Koomen Carla A. F. M., Aalberse Rob C., Bast Bert J. E. G., Knulst André C., van Ree Ronald IgE to Bet v 1 and profilin: cross-reactivity patterns and clinical relevance Journal of allergy and clinical immunology 2002;110 (3):435-442 [PubMed]
  • Wensing M., Penninks A. H., Hefle S. L., Akkerdaas J. H., van Ree R., Koppelman S. J., Bruijnzeel-Koomen C. A. F. M., Knulst A. C. The range of minimum provoking doses in hazelnut-allergic patients as determined by double-blind, placebo-controlled food challenges Clinical and experimental allergy 2002;32 (12):1757-1762 [PubMed]

2001

  • Aalberse R. C., Akkerdaas J., van Ree R. Cross-reactivity of IgE antibodies to allergens Allergy 2001;56 (6):478-490 [PubMed]
  • Asero R., Mistrello G., Roncarolo D., de Vries S. C., Gautier M. F., Ciurana C. L., Verbeek E., Mohammadi T., Knul-Brettlova V., Akkerdaas J. H., Bulder I., Aalberse R. C., van Ree R. Lipid transfer protein: a pan-allergen in plant-derived foods that is highly resistant to pepsin digestion International archives of allergy and immunology 2001;124 (1-3):67-69 [PubMed]

2000

  • Beta(1,2)-xylose and alpha(1,3)-fucose residues have a strong contribution in IgE binding to plant glycoallergens Journal of biological chemistry 2000;275 (15):11451-11458 [PubMed]
  • Lipid transfer protein: a pan-allergen in plant-derived foods that is highly resistant to pepsin digestion International archives of allergy and immunology 2000;122 (1):20-32 [PubMed]

1999

  • How far can we simplify in vitro diagnostics for Fagales tree pollen allergy? A study with three whole pollen extracts and purified natural and recombinant allergens Clinical and experimental allergy 1999;29 (6):848-855 [PubMed]

1997

  • Poor biologic activity of cross-reactive IgE directed to carbohydrate determinants of glycoproteins Journal of allergy and clinical immunology 1997;100 (3):327-334 [PubMed]

1996

  • Asthma after consumption of snails in house-dust-mite-allergic patients: a case of IgE cross-reactivity Allergy 1996;51 (6):387-393 [PubMed]
  • Possible induction of food allergy during mite immunotherapy Allergy 1996;51 (2):108-113 [PubMed]
  • Silverfish protein in house dust in relation to mite and total arthropod level Clinical and experimental allergy 1996;26 (10):1171-1176 [PubMed]

1995

  • IgE antibodies reactive with silverfish, cockroach and chironomid are frequently found in mite-positive allergic patients International archives of allergy and immunology 1995;108 (2):165-169 [PubMed]
  • Multiplicity of cross-reactive epitopes on Bet v I as detected with monoclonal antibodies and human IgE Allergy 1995;50 (3):215-220 [PubMed]
  • Vineyard snail allergy possibly induced by sensitization to house-dust mite (Dermatophagoides pteronyssinus) Allergy 1995;50 (5):438-440 [PubMed]

1994

  • Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects International archives of allergy and immunology 1994;105 (1):56-61 [PubMed]