PhD K.H.E.W.J. Sliepen

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PhD K.H.E.W.J. Sliepen

Position
Research Associate
Main activities
Research
Specialisation
hepatitis C virus (HCV), HIV-1, envelope glycoproteins, vaccines, nanoparticles
Focus of research

Designing hepatitis C virus (HCV) E1E2 glycoproteins for structural studies and vaccine studies.

Producing and designing novel HIV-1 envelope glycoproteins.

Key publications
  • Sliepen Kwinten, Han Byung Woo, Bontjer Ilja, Mooij Petra, Garces Fernando, Behrens Anna-Janina, Rantalainen Kimmo, Kumar Sonu, Sarkar Anita, Brouwer Philip J. M., Hua Yuanzi, Tolazzi Monica, Schermer Edith, Torres Jonathan L., Ozorowski Gabriel, van der Woude Patricia, de la Peña Alba Torrents, van Breemen Mariëlle J., Camacho-Sánchez Juan Miguel, Burger Judith A., Medina-Ramírez Max, González Nuria, Alcami Jose, LaBranche Celia, Scarlatti Gabriella, van Gils Marit J., Crispin Max, Montefiori David C., Ward Andrew B., Koopman Gerrit, Moore John P., Shattock Robin J., Bogers Willy M., Wilson Ian A., Sanders Rogier W. Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence Nature communications 2019;10 (1) [PubMed]
  • Sliepen Kwinten, Sanders Rogier W. HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies Expert review of vaccines 2016;15 (3):349-365 [PubMed]
  • Sliepen Kwinten, Ozorowski Gabriel, Burger Judith A., van Montfort Thijs, Stunnenberg Melissa, Labranche Celia, Montefiori David C., Moore John P., Ward Andrew B., Sanders Rogier W. Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity Retrovirology 2015;12 (1):82 [PubMed]
All Publications
Research programmes

Prof. PhD R.W. Sanders (HIV vaccine research aimed at the induction of neutralizing antibodies)