R. Hoekstra PhD publications

2020

• Chamuleau Robert A. F. M., Hoekstra Ruurdtje End-stage liver failure: filling the treatment gap at the intensive care unit Journal of Artificial Organs 2020;23 (2):113-123 [PubMed]
• Adam Aziza A. A., Jongejan Aldo, Moerland Perry D., van der Mark Vincent A., Oude Elferink Ronald P., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Genome-wide expression profiling reveals increased stability and mitochondrial energy metabolism of the human liver cell line HepaRG-CAR Cytotechnology 2020;72 (3):377-395 [PubMed]
• van der Mark Vincent A., Adam Aziza A. A., Chang Jung-Chin, Oude Elferink Ronald P., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Overexpression of the constitutive androstane receptor and shaken 3D-culturing increase biotransformation and oxidative phosphorylation and sensitivity to mitochondrial amiodarone toxicity of HepaRG cells Toxicology and applied pharmacology 2020;399 [PubMed]

2019

• Schneeberger Kerstin, Sánchez-Romero Natalia, Ye Shicheng, van Steenbeek Frank G, Oosterhoff Loes A, Pla Palacin Iris, Chen Chen, van Wolferen Monique E, van Tienderen Gilles, Lieshout Ruby, Colemonts-Vroninks Haaike, Schene Imre, Hoekstra Ruurdtje, Verstegen Monique M A, van der Laan Luc J W, Penning Louis C, Fuchs Sabine A, Clevers Hans, De Kock Joery, Baptista Pedro M, Spee Bart Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells Hepatology (Baltimore, Md.) 2019 [PubMed]
• Adam Aziza A. A., van der Mark Vincent A., Ruiter Jos P. N., Wanders Ronald J. A., Oude Elferink Ronald P. J., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Overexpression of carbamoyl-phosphate synthase 1 significantly improves ureagenesis of human liver HepaRG cells only when cultured under shaking conditions Mitochondrion 2019;47:298-308 [PubMed]
• Adam Aziza A. A. The role of mitochondria in human liver cell line differentiation for bioartificial livers 2019. 221p. ISBN 9789492679895. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Oude Elferink R. P. J.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)

2018

• Adam Aziza A. A., van Wenum Martien, van der Mark Vincent A., Jongejan Aldo, Moerland Perry D., Houtkooper Riekelt H., Wanders Ronald J. A., Oude Elferink Ronald P., Chamuleau Robert A. F. M., Hoekstra Ruurdtje AMC-Bio-Artificial Liver culturing enhances mitochondrial biogenesis in human liver cell lines: The role of oxygen, medium perfusion and 3D configuration Mitochondrion 2018;39:30-42 [PubMed]
• Adam Aziza A. A., van der Mark Vincent A., Donkers Joanne M., Wildenberg Manon E., Oude Elferink Ronald P. J., Chamuleau Robert A. F. M., Hoekstra Ruurdtje A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines PLoS ONE 2018;13 (4) [PubMed]
• Spijker A. T., van Zaane J., Koenders M. A., Hoekstra R., Kupka R. W. Bipolaire stoornissen en alcoholafhankelijkheid; praktische aanbevelingen voor behandeling op basis van een systematische literatuurstudie Tijdschrift voor psychiatrie 2018;60 (2):87-95 [PubMed]
• van Wenum Martien, Treskes Philipp, Adam Aziza A. A., van der Mark Vincent. A., Jongejan Aldo, Moerland Perry D., van Gulik Thomas M., Oude Elferink Ronald P. J., Chamuleau Robert A. F. M., Hoekstra Ruurdtje HepaRG-Progenitor Cell Derived Hepatocytes Cultured in Bioartificial Livers Are Protected from Healthy- and Acute Liver Failure-Plasma Induced Toxicity Cellular physiology and biochemistry 2018;48 (5):2189-2204 [PubMed]
• Gilglioni Eduardo H., Chang Jung Chin, Duijst Suzanne, Go Simei, Adam Aziza A. A. , Hoekstra Ruurdtje, Verhoeven Arthur J., Ishii-Iwamoto Emy L., Oude Elferink Ronald P. J. Improved oxygenation dramatically alters metabolism and gene expression in cultured primary mouse hepatocytes Hepatology Communications 2018;2 (3):299-312 [PubMed]
• van Wenum Martien, Adam Aziza A. A., van der Mark Vincent A., Chang Jung-Chin, Wildenberg Manon E., Hendriks Erik J., Jongejan Aldo, Moerland Perry D., van Gulik Thomas M., Oude Elferink Ronald P., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines Journal of cell communication and signaling 2018;12 (3):575 [PubMed]
• van Wenum Martinus Preclinical development of the AMC-HepaRG-Bioartificial Liver 2018. ISBN 9789462339248. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik T. M.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)

2017

• Egorov D., Hoekstra R., Schlathölter T. A comparative VUV absorption mass-spectroscopy study on protonated peptides of different size Physical chemistry chemical physics 2017;19 (31):20608-20618 [PubMed]
• Moedas M. F., Adam A. A. A., Farelo M. A., IJlst L., Chamuleau R. A. F. M., Hoekstra R., Wanders R. J. A., Silva M. F. B. Advances in methods for characterization of hepatic urea cycle enzymatic activity in HepaRG cells using UPLC-MS/MS Analytical biochemistry 2017;535:47-55 [PubMed]
• van Wenum Martien, Treskes Philipp, Tang Chung-Yin, Coppens Esmee J., Jansen Koen, Hendriks Erik J., Camus Sandrine, van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Scaling-up of a HepaRG progenitor cell based bioartificial liver: optimization for clinical application and transport BIOFABRICATION 2017;9 (3):035001 [PubMed]
• van der Mark Vincent A., Rudi de Waart D., Shevchenko Valery, Elferink Ronald P. J. Oude, Chamuleau Robert A. F. M., Hoekstra Ruurdtje Stable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG Cells Drug metabolism and disposition: the biological fate of chemicals 2017;45 (1):56-67 [PubMed]

2016

• van Wenum Martien, Adam Aziza A. A., Hakvoort Theodorus B. M., Hendriks Erik J., Shevchenko Valery, van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Selecting Cells for Bioartificial Liver Devices and the Importance of a 3D Culture Environment: A Functional Comparison between the HepaRG and C3A Cell Lines International journal of biological sciences 2016;12 (8):964-978 [PubMed]

2015

• Huch Meritxell, Gehart Helmuth, van Boxtel Ruben, Hamer Karien, Blokzijl Francis, Verstegen Monique M. A., Ellis Ewa, van Wenum Martien, Fuchs Sabine A., de Ligt Joep, van de Wetering Marc, Sasaki Nobuo, Boers Susanne J., Kemperman Hans, de Jonge Jeroen, Ijzermans Jan N. M., Nieuwenhuis Edward E. S., Hoekstra Ruurdtje, Strom Stephen, Vries Robert R. G., van der Laan Luc J. W., Cuppen Edwin, Clevers Hans Long-term culture of genome-stable bipotent stem cells from adult human liver Cell 2015;160 (1-2):299-312 [PubMed]
• Hoekstra R., van Wenum M., Chamuleau R. A. F. M. Pivotal preclinical trial of the spheroid reservoir bioartificial liver Journal of hepatology 2015;63 (4):1051-1052 [PubMed]

2014

• van Wenum Martien, Chamuleau Robert Afm, van Gulik Thomas M., Siliakus Adriaan, Seppen Jurgen, Hoekstra Ruurdtje Bioartificial livers in vitro and in vivo: tailoring biocomponents to the expanding variety of applications Expert opinion on biological therapy 2014;14 (12):1745-1760 [PubMed]
• El Filali Ebtisam, Duijst Suzanne, Hiralall Johan K., Legrand Nicolas, van Gulik Thomas, Hoekstra Ruurdtje, Seppen Jurgen Human fetal liver cells for regulated ex vivo erythropoietin gene therapy Molecular therapy. Methods & clinical development 2014;1:UNSP 14003 [PubMed]

2013

• Nibourg Geert A. A., Hoekstra Ruurdtje, van der Hoeven Tessa V., Ackermans Mariette T., Hakvoort Theodorus B. M., van Gulik Thomas M., Chamuleau Robert A. F. M. Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-bioartificial liver Liver international 2013;33 (4):516-524 [PubMed]
• Nibourg Geert A. A., Hoekstra Ruurdtje, van der Hoeven Tessa V., Ackermans Mariëtte T., Hakvoort Theodorus B. M., van Gulik Thomas M., Chamuleau Robert A. F. M. Increased hepatic functionality of the human hepatoma cell line HepaRG cultured in the AMC bioreactor international journal of biochemistry & cell biology 2013;45 (8):1860-1868 [PubMed]
• Hoekstra Ruurdtje, Nibourg Geert A. A., van der Hoeven Tessa V., Plomer Gabrielle, Seppen Jurgen, Ackermans Mariëtte T., Camus Sandrine, Kulik Wim, van Gulik Thomas M., Elferink Ronald P. Oude, Chamuleau Robert A. F. M. Phase 1 and phase 2 drug metabolism and bile acid production of HepaRG cells in a bioartificial liver in absence of dimethyl sulfoxide Drug metabolism and disposition: the biological fate of chemicals 2013;41 (3):562-567 [PubMed]

2012

• Nibourg Geert A. A. Human liver cell lines for the AMC-bioarteficial liver 2012. 236p. ISBN 9789461083609. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik T. M.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)
• Nibourg Geert A. A., Chamuleau Robert A. F. M., van der Hoeven Tessa V., Maas Martinus A. W., Ruiter An F. C., Lamers Wouter H., Oude Elferink Ronald P. J., van Gulik Thomas M., Hoekstra Ruurdtje Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure PLoS ONE 2012;7 (6):e38778 [PubMed]
• Nibourg Geert A. A., Boer Justin D., van der Hoeven Tessa V., Ackermans Mariëtte T., van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Perfusion flow rate substantially contributes to the performance of the HepaRG-AMC-bioartificial liver Biotechnology and bioengineering 2012;109 (12):3182-3188 [PubMed]
• Nibourg Geert A. A., Chamuleau Robert A. F. M., van Gulik Thomas M., Hoekstra Ruurdtje Proliferative human cell sources applied as biocomponent in bioartificial livers: a review Expert opinion on biological therapy 2012;12 (7):905-921 [PubMed]
• de Graaf Wilmar, Heger Michal, Spruijt Onno, Maas Adrie, de Bruin Kora, Hoekstra Ruurdtje, Bennink Roelof J., van Gulik Thomas M. Quantitative Assessment of Liver Function after Ischemia-Reperfusion Injury and Partial Hepatectomy in Rats Journal of surgical research 2012;172 (1):85-94 [PubMed]
• Hoekstra Ruurdtje, Nibourg Geert A. A., van der Hoeven Tessa V., Ackermans Mariëtte T., Hakvoort Theodorus B. M., van Gulik Thomas M., Oude Elferink Ronald P., Chamuleau Robert A. F. M. The effect of rat acute-liver-failure plasma on HepaRG cells International journal of artificial organs 2012;35 (11):1006-1014 [PubMed]

2011

• Hoekstra Ruurdtje, Nibourg Geert A. A., van der Hoeven Tessa V., Ackermans Mariëtte T., Hakvoort Theodorus B. M., van Gulik Thomas M., Lamers Wouter H., Elferink Ronald P. Oude, Chamuleau Robert A. F. M. The HepaRG cell line is suitable for bioartificial liver application international journal of biochemistry & cell biology 2011;43 (10):1483-1489 [PubMed]

2010

• Nibourg Geert A. A., Huisman Maarten T., van der Hoeven Tessa V., van Gulik Thomas M., Chamuleau Robert A. F. M., Hoekstra Ruurdtje Stable Overexpression of Pregnane X Receptor in HepG2 Cells Increases Its Potential for Bioartificial Liver Application Liver transplantation 2010;16 (9):1075-1085 [PubMed]

2009

• Deurholt Tanja, van Til Niek P., Chhatta Aniska A., ten Bloemendaal Lysbeth, Schwartlander Ruth, Payne Catherine, Plevris John N., Sauer Igor M., Chamuleau Robert A. F. M., Oude Elferink Ronald P. J., Seppen Jurgen, Hoekstra Ruurdtje Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes BMC biotechnology 2009;9 (1):89 [PubMed]

2008

• Poyck Paul P. C., Mareels Guy, Hoekstra Ruurdtje, van Wijk Albert C. W. A., van der Hoeven Tessa V., van Gulik Thomas M., Verdonck Pascal R., Chamuleau Robert A. F. M. Enhanced oxygen availability improves liver-specific functions of the AMC bioartificial liver Artificial organs 2008;32 (2):116-126 [PubMed]
• Poyck Paul P. C., van Wijk Albert C. W. A., van der Hoeven Tessa V., de Waart Dirk R., Chamuleau Robert A. F. M., van Gulik Thomas M., Oude Elferink Ronald P. J., Hoekstra Ruurdtje Evaluation of a new immortalized human fetal liver cell line (cBAL111) for application in bioartificial liver Journal of hepatology 2008;48 (2):266-275 [PubMed]
• Poyck Paul P. C., Hoekstra Ruurdtje, Vermeulen Jacqueline L. M., van Wijk Albert C. W. A., Chamuleau Robert A. F. M., Hakvoort Theodorus B. M., van Gulik Thomas M., Lamers Wouter H. Expression of glutamine synthetase and carbamoylphosphate synthetase i in a bioartificial liver: markers for the development of zonation in vitro Cells, tissues, organs 2008;188 (3):259-269 [PubMed]

2007

• Deurholt Tanja Development of an immortalised human hepatocyte cell line for the AMC bio-artificial liver 2007. 141p. ISBN 9789090225098. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Oude Elferink Ronald P. J.; Co-supervisors: Chamuleau Robert A. F. M., Hoekstra R.)
• Poyck Paul P. C., Hoekstra Ruurdtje, van Wijk Albert C. W. A., Attanasio Chiara, Calise Fulvio, Chamuleau Robert A. F. M., van Gulik Thomas M. Functional and morphological comparison of three primary liver cell types cultured in the AMC bioartificial liver Liver transplantation 2007;13 (4):589-598 [PubMed]
• Poyck P. P. C., Pless G., Hoekstra R., Roth S., van Wijk A. C. W. A., Schwartlander R., van Gulik T. M., Sauer I. M., Chamuleau R. A. F. M. In vitro comparison of two bioartificial liver support systems: MELS CellModule and AMC-BAL International journal of artificial organs 2007;30 (3):183-191 [PubMed]
• Poyck Paul P. C., Hoekstra Ruurdtje, Chhatta Aniska, ten Bloemendaal Lysbeth, van Wijk Albert C. W. A., Galavotti Daniele, van Gulik Thomas M., Chamuleau Robert A. F. M. Time-related analysis of metabolic liver functions, cellular morphology, and gene expression of hepatocytes cultured in the bioartificial liver of the Academic Medical Center in Amsterdam (AMC-BAL) Tissue engineering 2007;13 (6):1235-1246 [PubMed]
• Poyck Paul P. C. Towards application of a human liver cell line for use in the AMC bioartificial liver 2007. 351p. ISBN 9789090220505. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik Thomas M.; Co-supervisors: Chamuleau Robert A. F. M., Hoekstra Ruurdtje)

2006

• Hoekstra Ruurdtje, Deurholt Tanja, ten Bloemendaal Lysbeth, Desille Mireille, van Wijk Albert C. W. A., Clement Bruno, Oude Elferink Ronald P. J., van Gulik Thomas M., Chamuleaut Robert A. F. M. Assessment of in vitro applicability of reversibly immortalized NKNT-3 cells and clonal derivatives Cell transplantation 2006;15 (5):423-433 [PubMed]
• Deurholt Tanja, ten Bloemendaal Lysbeth, Chhatta Aniska A., van Wijk Albert C. W. A., Weijer Kees, Seppen Jurgen, Elferink Ronald P. J. Oude, Chamuleau Robert A. F. M., Hoekstra Ruurdtje In vitro functionality of human fetal liver cells and clonal derivatives under proliferative conditions Cell transplantation 2006;15 (8-9):811-822 [PubMed]
• Lie-A-Ling Michael, Bakker Conny T., Deurholt Tanja, Hoekstra Ruurdtje, Wesseling John G., Afford Simon C., Bosma Piter J. Selection of tumour specific promoters for adenoviral gene therapy of cholangiocarcinoma Journal of hepatology 2006;44 (1):126-133 [PubMed]
• van de Kerkhove M. P., Hoekstra R., van Nooijen F. C., Spoelstra F. O. B., Doorschodt B. M., van Wijk A. C. W. A., Poyck P. P. C., Chamuleau R. A. F. M., van Gulik T. M. Subnormothermic preservation maintains viability and function in a porcine hepatocyte culture model simulating bioreactor transport Cell transplantation 2006;15 (2):161-168 [PubMed]

2005

• van de Kerkhove M. P., Poyck P. P. C., van Wijk A. C. W. A., Galavotti D., Hoekstra R., van Gulik T. M., Chamuleau R. A. F. M. Assessment and improvement of liver specific function of the AMC-bioartificial liver International journal of artificial organs 2005;28 (6):617-630 [PubMed]
• van de Kerkhove Maarten-Paul, Germans Menno R., Deurholt Tanja, Hoekstra Ruurdtje, Joziasse David H., van Wijk Albert C. W. A., van Gulik Thomas M., Chamuleau Robert A. F. M., Roos Anja Evidence for Galalpha(1-3)Gal expression on primary porcine hepatocytes: implications for bioartificial liver systems Journal of hepatology 2005;42 (4):541-547 [PubMed]
• Hoekstra Ruurdtje, Deurholt Tanja, Poyck Paul P. C., ten Bloemendaal Lysbeth, Chhatta Aniska A. Increased reproducibility of quantitative reverse transcriptase-PCR Analytical biochemistry 2005;340 (2):376-379 [PubMed]
• van de Kerkhove M. P., Poyck P. P. C., Deurholt T., Hoekstra R., Chamuleau R. A. F. M., van Gulik T. M. Liver support therapy: an overview of the AMC-bioartificial liver research Digestive surgery 2005;22 (4):254-264 [PubMed]
• Poyck Paul P. C., Hoekstra Ruurdtje, van Wijk Albert C. W. A., ten Bloemendaal Lysbeth, Chamuleau Robert A. F. M., van Gulik Thomas M. Mild hypothermic preservation for transport purposes of the AMC bioartificial liver charged with porcine hepatocytes Transplantation 2005;80 (9):1153-1160 [PubMed]
• Di Nicuolo Giuseppe, van de Kerkhove Maarten-Paul, Hoekstra Ruurdtje, Beld Marcel G. H. M., Amoroso Pietro, Battisti Sonia, Starace Maria, di Florio Ernesto, Scuderi Vincenzo, Scala Simona, Bracco Adele, Mancini Antonio, Chamuleau Robert A. F. M., Calise Fulvio No evidence of in vitro and in vivo porcine endogenous retrovirus infection after plasmapheresis through the AMC-bioartificial liver Xenotransplantation 2005;12 (4):286-292 [PubMed]
• Chamuleau Robert A. F. M., Deurholt Tanja, Hoekstra Ruurdtje Which are the right cells to be used in a bioartificial liver? Metabolic brain disease 2005;20 (4):327-335 [PubMed]

2004

• van de Kerkhove Maarten Paul, Hoekstra Ruurdtje, Chamuleau Robert A. F. M., van Gulik Thomas M. Clinical application of bioartificial liver support systems Annals of surgery 2004;240 (2):216-230 [PubMed]
• Roos Marleen H., Otsen Myrthe, Hoekstra Ruurdtje, Veenstra Jetty G., Lenstra Johannes A. Genetic analysis of inbreeding of two strains of the parasitic nematode Haemonchus contortus International journal for parasitology 2004;34 (1):109-115 [PubMed]
• van de Kerkhove M.-P., Hoekstra R., van Gulik T. M., Chamuleau R. A. F. M. Large animal models of fulminant hepatic failure in artificial and bioartificial liver support research Biomaterials 2004;25 (9):1613-1625 [PubMed]
• van de Kerkhove M. P. Optimization and clinical application of the AMC-bioarteficial liver 2004. 187p. ISBN 9789090479378. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Gulik T. M.; Co-supervisors: Chamuleau R. A. F. M., Hoekstra R.)

2002

• van de Kerkhove M. P., Di Florio E., Scuderi V., Mancini A., Belli A., Bracco A., Dauri M., Tisone G., Di Nicuolo G., Amoroso P., Spadari A., Lombardi G., Hoekstra R., Calise F., Chamuleau R. A. F. M. Phase I clinical trial with the AMC-bioartificial liver International journal of artificial organs 2002;25 (10):950-959 [PubMed]
• Hoekstra R., Chamuleau R. A. F. M. Recent developments on human cell lines for the bioartificial liver International journal of artificial organs 2002;25 (3):182-191 [PubMed]

2001

• Otsen M., Hoekstra R., Plas M. E., Buntjer J. B., Lenstra J. A., Roos M. H. Amplified fragment length polymorphism analysis of genetic diversity of Haemonchus contortus during selection for drug resistance International journal for parasitology 2001;31 (10):1138-1143 [PubMed]
• Walker J., Hoekstra R., Roos M. H., Wiley L. J., Weiss A. S., Sangster N. C., Tait A. Cloning and structural analysis of partial acetylcholine receptor subunit genes from the parasitic nematode Teladorsagia circumcincta Veterinary parasitology 2001;97 (4):329-335 [PubMed]

2000

• Hoekstra R., Visser A., Otsen M., Tibben J., Lenstra J. A., Roos M. H. EST sequencing of the parasitic nematode Haemonchus contortus suggests a shift in gene expression during transition to the parasitic stages Molecular and biochemical parasitology 2000;110 (1):53-68 [PubMed]
• Otsen M., Plas M. E., Groeneveld J., Roos M. H., Lenstra J. A., Hoekstra R. Genetic markers for the parasitic nematode Haemonchus contortus based on intron sequences Experimental parasitology 2000;95 (3):226-229 [PubMed]
• Otsen M., Plas M. E., Lenstra J. A., Roos M. H., Hoekstra R. Microsatellite diversity of isolates of the parasitic nematode Haemonchus contortus Molecular and biochemical parasitology 2000;110 (1):69-77 [PubMed]
• Hoekstra R., Otsen M., Tibben J., Lenstra J. A., Roos M. H. Non-autonomous transposable elements in the genome of the parasitic nematode Haemonchus contortus Molecular and biochemical parasitology 2000;106 (1):163-168 [PubMed]
• Hoekstra R., Otsen M., Tibben J., Lenstra J. A., Roos M. H. Transposon associated markers for the parasitic nematode Haemonchus contortus Molecular and biochemical parasitology 2000;105 (1):127-135 [PubMed]

1999

• Hoekstra R., Otsen M., Lenstra J. A., Roos M. H. Characterisation of a polymorphic Tc1-like transposable element of the parasitic nematode Haemonchus contortus Molecular and biochemical parasitology 1999;102 (1):157-166 [PubMed]

1998

• Roos M. H., Hoekstra R., Plas M. E., Otsen M., Lenstra J. A. Polymorphic DNA markers in the genome of parasitic nematodes Journal of helminthology 1998;72 (4):291-294 [PubMed]

1997

• Hoekstra R., Visser A., Wiley L. J., Weiss A. S., Sangster N. C., Roos M. H. Characterization of an acetylcholine receptor gene of Haemonchus contortus in relation to levamisole resistance Molecular and biochemical parasitology 1997;84 (2):179-187 [PubMed]
• Hoekstra R., Criado-Fornelio A., Fakkeldij J., Bergman J., Roos M. H. Microsatellites of the parasitic nematode Haemonchus contortus: polymorphism and linkage with a direct repeat Molecular and biochemical parasitology 1997;89 (1):97-107 [PubMed]
• Hoekstra R., Borgsteede F. H., Boersema J. H., Roos M. H. Selection for high levamisole resistance in Haemonchus contortus monitored with an egg-hatch assay International journal for parasitology 1997;27 (11):1395-1400 [PubMed]

1994

• Hoekstra R., Groeneveld P., van Verseveld H. W., Stouthamer A. H., Planta R. J. Transcription regulation of ribosomal protein genes at different growth rates in continuous cultures of Kluyveromyces yeasts Yeast (Chichester, England) 1994;10 (5):637-651 [PubMed]

1992

• Bergkamp-Steffens G. K., Hoekstra R., Planta R. J. Structural and putative regulatory sequences of Kluyveromyces ribosomal protein genes Yeast (Chichester, England) 1992;8 (11):903-922 [PubMed]
• Hoekstra R., Ferreira P. M., Bootsman T. C., Mager W. H., Planta R. J. Structure and expression of the ABF1-regulated ribosomal protein S33 gene in Kluyveromyces Yeast (Chichester, England) 1992;8 (11):949-959 [PubMed]

1988

• Janssen D, B,, Grobben G., Hoekstra R., Oldenhuis R., Witholt B. DEGRADATION OF TRANS-1,2-DICHLOROETHENE BY MIXED AND PURE CULTURES OF METHANOTROPHIC BACTERIA Applied microbiology and biotechnology 1988;29 (4):392-399
• Visser R. G., Hoekstra R., van der Leij F. R., Pijnacker L. P., Witholt B., Feenstra W. J. In situ hybridization to somatic metaphase chromosomes of potato TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 1988;76 (3):420-424 [PubMed]