PhD W.D. Eggink publications

2019

• Welkers Matthijs R. A., Pawestri Hana A., Fonville Judy M., Sampurno Ondri D., Pater Maarten, Holwerda Melle, Han Alvin X., Russell Colin A., Jeeninga Rienk E., Setiawaty Vivi, de Jong Menno D., Eggink Dirk Genetic diversity and host adaptation of avian H5N1 influenza viruses during human infection Emerging microbes and infections 2019;8 (1):262-271 [PubMed]
• Eggink Dirk, Bontjer Ilja, de Taeye Steven W., Langedijk Johannes P. M., Berkhout Ben, Sanders Rogier W. HIV-1 anchor inhibitors and membrane fusion inhibitors target distinct but overlapping steps in virus entry Journal of biological chemistry 2019;294 (15):5736-5746 [PubMed]
• Broszeit Frederik, Tzarum Netanel, Zhu Xueyong, Nemanichvili Nikoloz, Eggink Dirk, Leenders Tim, Li Zeshi, Liu Lin, Wolfert Margreet A., Papanikolaou Andreas, Martínez-Romero Carles, Gagarinov Ivan A., Yu Wenli, García-Sastre Adolfo, Wennekes Tom, Okamatsu Masatoshi, Verheije Monique H., Wilson Ian A., Boons Geert-Jan, de Vries Robert P. N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses Cell reports 2019;27 (11):3284-3294.e6 [PubMed]

2018

• Newling Melissa, Hoepel Willianne, Vogelpoel Lisa T. C., Heineke Marieke H., van Burgsteden Johan A., Taanman-Kueter Esther W. M., Eggink Dirk, Kuijpers Taco W., Beaumont Tim, van Egmond Marjolein, Kapsenberg Martien L., Baeten Dominique L. P., den Dunnen Jeroen, Jong Esther C. de Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells European journal of immunology 2018;48 (11):1796-1809 [PubMed]
• Poen Marjolein J., Bestebroer Theo M., Vuong Oanh, Scheuer Rachel D., van der Jeugd Henk P., Kleyheeg Erik, Eggink Dirk, Lexmond Pascal, van den Brand Judith M. A., Begeman Lineke, van der Vliet Stefan, Müskens Gerhard J. D. M., Majoor Frank A., Koopmans Marion P. G., Kuiken Thijs, Fouchier Ron A. M. Local amplification of highly pathogenic avian influenza H5N8 viruses in wild birds in the Netherlands, 2016 to 2017 Euro surveillance 2018;23 (4):6 17-00449-20 [PubMed]

2016

• Eggink Dirk, de Taeye Steven W., Bontjer Ilja, Klasse Per Johan, Langedijk Johannes P. M., Berkhout Ben, Sanders Rogier W. HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike Journal of virology 2016;90 (23):10587-10599 [PubMed]

2015

• de Taeye Steven W., Ozorowski Gabriel, Torrents de la Peña Alba, Guttman Miklos, Julien Jean-Philippe, van den Kerkhof Tom L. G. M., Burger Judith A., Pritchard Laura K., Pugach Pavel, Yasmeen Anila, Crampton Jordan, Hu Joyce, Bontjer Ilja, Torres Jonathan L., Arendt Heather, DeStefano Joanne, Koff Wayne C., Schuitemaker Hanneke, Eggink Dirk, Berkhout Ben, Dean Hansi, Labranche Celia, Crotty Shane, Crispin Max, Montefiori David C., Klasse P. J., Lee Kelly K., Moore John P., Wilson Ian A., Ward Andrew B., Sanders Rogier W. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes Cell 2015;163 (7):1702-1715 [PubMed]

2013

• Bontjer Ilja, Melchers Mark, Tong Tommy, van Montfort Thijs, Eggink Dirk, Montefiori David, Olson William C., Moore John P., Binley James M., Berkhout Ben, Sanders Rogier W. Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers PLoS ONE 2013;8 (6):e67484 [PubMed]

2012

• de Vries Robert P., Smit Cornelis H., de Bruin Erwin, Rigter Alan, de Vries Erik, Cornelissen Lisette A. H. M., Eggink Dirk, Chung Nancy P. Y., Moore John P., Sanders Rogier W., Hokke Cornelis H., Koopmans Marion, Rottier Peter J. M., de Haan Cornelis A. M. Glycan-Dependent Immunogenicity of Recombinant Soluble Trimeric Hemagglutinin Journal of virology 2012;86 (21):11735-11744 [PubMed]
• Berkhout Ben, Eggink Dirk, Sanders Rogier W. Is there a future for antiviral fusion inhibitors? Current opinion in virology 2012;2 (1):50-59 [PubMed]
• Banerjee Kaustuv, Michael Elizabeth, Eggink Dirk, van Montfort Thijs, Lasnik Amanda B., Palmer Kenneth E., Sanders Rogier W., Moore John P., Klasse Per Johan Occluding the Mannose Moieties on Human Immunodeficiency Virus Type 1 gp120 with Griffithsin Improves the Antibody Responses to Both Proteins in Mice AIDS research and human retroviruses 2012;28 (2):206-214 [PubMed]
• Melchers Mark, Bontjer Ilja, Tong Tommy, Chung Nancy P. Y., Klasse Per Johan, Eggink Dirk, Montefiori David C., Gentile Maurizio, Cerutti Andrea, Olson William C., Berkhout Ben, Binley James M., Moore John P., Sanders Rogier W. Targeting HIV-1 Envelope Glycoprotein Trimers to B Cells by Using APRIL Improves Antibody Responses Journal of virology 2012;86 (5):2488-2500 [PubMed]

2011

• Melchers Mark, Matthews Katie, de Vries Robert P., Eggink Dirk, van Montfort Thijs, Bontjer Ilja, van de Sandt Carolien, David Kathryn, Berkhout Ben, Moore John P., Sanders Rogier W. A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells Retrovirology 2011;8 (1):48 [PubMed]
• van Montfort Thijs, Eggink Dirk, Boot Maikel, Tuen Michael, Hioe Catarina E., Berkhout Ben, Sanders Rogier W. HIV-1 N-glycan composition governs a balance between dendritic cell-mediated viral transmission and antigen presentation Journal of immunology (Baltimore, Md. 2011;187 (9):4676-4685 [PubMed]
• Berkhout Ben, Eggink Dirk New pathogenic viruses and novel antiviral drugs Expert review of anti-infective therapy 2011;9 (2):161-163 [PubMed]
• Eggink Dirk, Bontjer Ilja, Langedijk Johannes P. M., Berkhout Ben, Sanders Rogier W. Resistance of Human Immunodeficiency Virus Type 1 to a Third-Generation Fusion Inhibitor Requires Multiple Mutations in gp41 and Is Accompanied by a Dramatic Loss of gp41 Function Journal of virology 2011;85 (20):10785-10797 [PubMed]

2010

• Eggink Dirk, Melchers Mark, Wuhrer Manfred, van Montfort Thijs, dey Antu K., Naaijkens Benno A., David Kathryn B., Le Douce Valentin, Deelder Andre M., Kang Kenneth, Olson William C., Berkhout Ben, Hokke Cornelis H., Moore John P., Sanders Rogier W. Corrigendum to: Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function (vol 401, pg 236, 2010) Virology 2010;406 (1):162-163
• Eggink Dirk, Berkhout Ben, Sanders Rogier W. Inhibition of HIV-1 by Fusion Inhibitors Current pharmaceutical design 2010;16 (33):3716-3728 [PubMed]
• Eggink Dirk, Melchers Mark, Wuhrer Manfred, van Montfort Thijs, dey Antu K., Naaijkens Benno A., David Kathryn B., Le Douce Valentin, Deelder André M., Kang Kenneth, Olson William C., Berkhout Ben, Hokke Cornelis H., Moore John P., Sanders Rogier W. Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function Virology 2010;401 (2):236-247 [PubMed]
• Eggink W. D. Resistance to HIV-1 fusion inhibitors 2010. 225p. ISBN 9789490371289. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Sanders R. W.)
• Binley James M., Ban Yih-En Andrew, Crooks Emma T., Eggink Dirk, Osawa Keiko, Schief William R., Sanders Rogier W. Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization Journal of virology 2010;84 (11):5637-5655 [PubMed]
• Bontjer Ilja, Melchers Mark, Eggink Dirk, David Kathryn, Moore John P., Berkhout Ben, Sanders Rogier W. Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution Journal of biological chemistry 2010;285 (47):36456-36470 [PubMed]

2009

• Eggink Dirk, Langedijk Johannes P. M., Bonvin Alexandre M. J. J., Deng Yiqun, Lu Min, Berkhout Ben, Sanders Rogier W. Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors Journal of biological chemistry 2009;284 (39):26941-26950 [PubMed]
• Bontjer Ilja, Land Aafke, Eggink Dirk, Verkade Erwin, Tuin Kiki, Baldwin Chris, Pollakis Georgios, Paxton William A., Braakman Ineke, Berkhout Ben, Sanders Rogier W. Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution Journal of virology 2009;83 (1):368-383 [PubMed]

2008

• Eggink Dirk, Baldwin Christopher E., Deng Yiqun, Langedijk Johannes P. M., Lu Min, Sanders Rogier W., Berkhout Ben Selection of T1249-resistant human immunodeficiency virus type 1 variants Journal of virology 2008;82 (13):6678-6688 [PubMed]
• Sanders Rogier W., van Anken Eelco, Nabatov Alexei A., Liscaljet I. Marije, Bontjer Ilja, Eggink Dirk, Melchers Mark, Busser Els, Dankers Martijn M., Groot Fedde, Braakman Ineke, Berkhout Ben, Paxton William A. The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion Retrovirology 2008;5:10 [PubMed]

2007

• Eggink Dirk, Melchers Mark, Sanders Rogier W. Antibodies to HIV-1: aiming at the right target Trends in microbiology 2007;15 (7):291-294 [PubMed]