Prof. A. Boelen PhD publications

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Publications Prof. PhD A. Boelen

Positions
Other Academic Staff, Full Professor, MD-PhD
Main activities
Patient care, Research
Specialisation
endocrinology, neonatal screening
Focus of research

Central and peripheral thyroid hormone metabolism during inflammation

Hypothalamus-pituitary-thyroid axis

2021

  • van der Spek Anne H., Fliers Eric, Boelen Anita Thyroid Hormone and Deiodination in Innate Immune Cells Endocrinology 2021;162 (1) [PubMed]

2020

  • Barendsen Rinse W., Dijkstra Inge M. E., Visser Wouter F., Alders Mariëlle, Bliek Jet, Boelen Anita, Bouva Marelle J., van der Crabben Saskia N., Elsinghorst Ellen, van Gorp Ankie G. M., Heijboer Annemieke C., Jansen Mandy, Jaspers Yorrick R. J., van Lenthe Henk, Metgod Ingrid, Mooij Christiaan F., van der Sluijs Elise H. C., van Trotsenburg A. S. Paul, Verschoof-Puite Rendelien K., Vaz Frédéric M., Waterham Hans R., Wijburg Frits A., Engelen Marc, Dekkers Eugènie, Kemp Stephan Adrenoleukodystrophy Newborn Screening in the Netherlands (SCAN Study): The X-Factor Frontiers in cell and developmental biology 2020;8 [PubMed]
  • Naafs Jolanda C, Heinen Charlotte A, Zwaveling-Soonawala Nitash, van der Schoor Sophie R D, van Tellingen Vera, Heijboer Annemieke C, Fliers Eric, Boelen Anita, van Trotsenburg A S Paul Age-Specific Reference Intervals for Plasma Free Thyroxine and Thyrotropin in Term Neonates During the First Two Weeks of Life Thyroid 2020;30 (8):1106-1111 [PubMed]
  • Fliers E., Boelen A. An update on non-thyroidal illness syndrome Journal of endocrinological investigation 2020 [PubMed]
  • Miro Caterina, di Cicco Emery, Ambrosio Raffaele, Mancino Giuseppina, di Girolamo Daniela, Cicatiello Annunziata Gaetana, Sagliocchi Serena, Nappi Annarita, de Stefano Maria Angela, Luongo Cristina, Antonini Dario, Visconte Feliciano, Varricchio Silvia, Ilardi Gennaro, del Vecchio Luigi, Staibano Stefania, Boelen Anita, Blanpain Cedric, Missero Caterina, Salvatore Domenico, Dentice Monica Author Correction: Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch (Nature Communications, (2019), 10, 1, (5410), 10.1038/s41467-019-13140-2) Nature communications 2020;11 (1) [PubMed]
  • Naafs Jolanda C, Marchal Jan Pieter, Fliers Eric, Verkerk Paul H, Luijten Michiel A J, Boelen Anita, van Trotsenburg A S Paul, Zwaveling-Soonawala Nitash Cognitive and motor outcome in patients with early-detected central congenital hypothyroidism compared with siblings Journal of clinical endocrinology and metabolism 2020 [PubMed]
  • Stroek Kevin, Heijboer Annemieke C., Bouva Marelle J., van der Ploeg Catharina P. B., Heijnen Marie-Louise A., Weijman Gert, Bosch Annet M., de Jonge Robert, Schielen Peter C. J. I., van Trotsenburg A. S. Paul, Boelen Anita Critical evaluation of the newborn screening for congenital hypothyroidism in the Netherlands European journal of endocrinology / European Federation of Endocrine Societies 2020;183 (3):265-273 [PubMed]
  • Stroek Kevin, Boelen Anita, Bouva Marelle J., de Sain-van der Velden Monique, Schielen Peter C. J. I., Maase Rose, Engel Henk, Jakobs Bernadette, Kluijtmans Leo A. J., Mulder Margot F., Rubio-Gozalbo M. E., van Spronsen Francjan J., Visser Gepke, de Vries Maaike C., Williams Monique, Heijboer Annemieke C., Kemper Evelien A., Bosch Annet M. Evaluation of 11 years of newborn screening for maple syrup urine disease in the Netherlands and a systematic review of the literature: Strategies for optimization JIMD reports 2020;54 (1):68-78 [PubMed]
  • Donkers Joanne M., Roscam Abbing Reinout L. P., van Weeghel Michel, Levels Johannes H. M., Boelen Anita, Schinkel Alfred H., Oude Elferink Ronald P. J., van de Graaf Stan F. J. Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces Obesity Cellular and molecular gastroenterology and hepatology 2020;10 (3):451-466 [PubMed]
  • de Vries Emmely M., van Beeren Hermina C., van Wijk Albert C. W. A., Kalsbeek Andries, Romijn Johannes A., Fliers Eric, Boelen Anita Regulation of type 3 deiodinase in rodent liver and adipose tissue during fasting Endocrine connections 2020;9 (6):552-562 [PubMed]
  • Bloise Flavia Fonseca, Santos Anderson Teixeira, de Brito Juliana, de Andrade Cherley Borba Vieira, Oliveira Thamires Siqueira, de Souza Aline Fonseca Pereira, Fontes Klaus Novaes, Silva Johnatas D., Blanco Natália, Silva Pedro Leme, Rocco Patricia Rieken Macedo, Fliers Eric, Boelen Anita, da-Silva Wagner Seixas, Ortiga-Carvalho T. nia Maria Sepsis Impairs Thyroid Hormone Signaling and Mitochondrial Function in the Mouse Diaphragm Thyroid 2020;30 (7):1079-1090 [PubMed]
  • Rubingh Julia, van der Spek Anne, Fliers Eric, Boelen Anita The Role of Thyroid Hormone in the Innate and Adaptive Immune Response during Infection Comprehensive Physiology 2020;10 (4):1277-1287 [PubMed]
  • Williams Fiona L. R., Lindgren Alice, Watson Jennifer, Boelen Anita, Cheetham Timothy Thyroid function in preterm infants and neurodevelopment at 2 years Archives of disease in childhood. Fetal and neonatal edition 2020;105 (5):504-509 [PubMed]

2019

  • Carmody Colleen, Ogawa-Wong Ashley N., Martin Cecilia, Luongo Cristina, Zuidwijk Marian, Sager Benjamin, Petersen Travis, Roginski Guetter Adriana, Janssen Rob, Wu Elizabeth Y., Bogaards Sylvia, Neumann Neil M., Hau Kaman, Marsili Alessandro, Boelen Anita, Silva J. Enrique, Dentice Monica, Salvatore Domenico, Wagers Amy J., Larsen P. Reed, Simonides Warner S., Zavacki Ann Marie A Global Loss of Dio2 Leads to Unexpected Changes in Function and Fiber Types of Slow Skeletal Muscle in Male Mice Endocrinology 2019;160 (5):1205-1222 [PubMed]
  • Belegri Evangelia Diet-induced hypothalamic inflammation, cellular stress and the acute phase response 2019. 170p. ISBN 9789402815382. [UvA Dissertations Online] University of Amsterdam. (Supervisors: la Fleur S. E. , Fliers Eric; Co-supervisors: Boelen A. , Kalsbeek A.)
  • de Vries Emmely M., Surovtseva Olga, Vos Winnie G., Kunst Roni F., van Beeren Mieke, Kwakkel Joan, Chassande Olivier, Ackermans Mariette T., Fliers Eric, Boelen Anita Downregulation of Type 3 Deiodinase in the Hypothalamus during Inflammation Thyroid 2019;29 (9):1336-1343 [PubMed]
  • van der Linde Annelieke A. A., Schönbeck Yvonne, van der Kamp Hetty J., van den Akker Erica L. T., van Albada Mirjam E., Boelen Anita, Finken Martijn J. J., Hannema Sabine E., Hoorweg-Nijman Gera, Odink Roelof J., Schielen Peter C. J. I., Straetemans Saartje, van Trotsenburg Paul S., Claahsen-van der Grinten Hedi L., Verkerk Paul H. Evaluation of the Dutch neonatal screening for congenital adrenal hyperplasia Archives of disease in childhood 2019;104 (7):653-657 [PubMed]
  • van Lierop Antoon H, Bisschop Peter H, Boelen Anita, van Eeden Susanne, Engelman Anton F, Nieveen van Dijkum Elisabeth J, Klümpen Heinz-Josef Hypercalcaemia due to a calcitriol-producing neuroendocrine tumour Journal of surgical case reports 2019;2019 (12):rjz346 [PubMed]
  • Johann Kornelia, Cremer Anna Lena, Fischer Alexander W., Heine Markus, Pensado Eva Rial, Resch Julia, Nock Sebastian, Virtue Samuel, Harder Lisbeth, Oelkrug Rebecca, Astiz Mariana, Brabant Georg, Warner Amy, Vidal-Puig Antonio, Oster Henrik, Boelen Anita, López Miguel, Heeren Joerg, Dalley Jeffrey W., Backes Heiko, Mittag Jens Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption Cell reports 2019;27 (11):3385-3400.e3 [PubMed]
  • Miro Caterina, di Cicco Emery, Ambrosio Raffaele, Mancino Giuseppina, di Girolamo Daniela, Cicatiello Annunziata Gaetana, Sagliocchi Serena, Nappi Annarita, de Stefano Maria Angela, Luongo Cristina, Antonini Dario, Visconte Feliciano, Varricchio Silvia, Ilardi Gennaro, del Vecchio Luigi, Staibano Stefania, Boelen Anita, Blanpain Cedric, Missero Caterina, Salvatore Domenico, Dentice Monica Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch Nature communications 2019;10 (1) [PubMed]

2018

  • Williams Graham R., Boelen Anita, Refetoff Samuel 13th International workshop on resistance to thyroid hormone and thyroid hormone action Thyroid 2018;28 (6):690-691 [PubMed]
  • Zhang Zhi, Machado Frederico, Zhao Li, Heinen Charlotte A., Foppen Ewout, Ackermans Mariette T., Zhou Jiangning, Bisschop Peter H., Boelen Anita, Fliers Eric, Kalsbeek Andries Administration of thyrotropin-releasing hormone in the hypothalamic paraventricular nucleus of male rats mimics the metabolic cold defense response Neuroendocrinology 2018;107 (3):267-279 [PubMed]
  • Eggink Hannah M., Tambyrajah Lauren L., van den Berg Rosa, Mol Isabel M., van den Heuvel Jose K., Koehorst Martijn, Groen Albert K., Boelen Anita, Kalsbeek Andries, Romijn Johannes A., Rensen Patrick C. N., Kooijman Sander, Soeters Maarten R. Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice Journal of endocrinology 2018;236 (2):85-97 [PubMed]
  • Heinen Charlotte A., Zhang Zhi, Klieverik Lars P., de Wit Tim C., Poel Edwin, Yaqub Maqsood, Boelen Anita, Kalsbeek Andries, Bisschop Peter H., van Trotsenburg A. S. Paul, Verberne Hein J., Booij Jan, Fliers Eric Effects of intravenous thyrotropin-releasing hormone on18F-fluorodeoxyglucose uptake in human brown adipose tissue: a randomized controlled trial European journal of endocrinology / European Federation of Endocrine Societies 2018;179 (1):31-38 [PubMed]
  • Heinen Charlotte A. Genetic causes and neonatal diagnosis of congenital isolated central hypothyroidism 2018. 254p. ISBN 9789402809589. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Fliers E., van Trotsenburg A. S. P.; Co-supervisors: Hennekam R. C. M., Boelen A.)
  • Heinen Charlotte A., de Vries Emmely M., Alders Mariëlle, Bikker Hennie, Zwaveling-Soonawala Nitash, van den Akker Erica L. T., Bakker Boudewijn, Hoorweg-Nijman Gera, Roelfsema Ferdinand, Hennekam Raoul C., Boelen Anita, Paul van Trotsenburg A. S., Fliers Eric Mutations in IRS4 are associated with central hypothyroidism Journal of medical genetics 2018;55 (10):693-700 [PubMed]
  • Belegri Evita, Eggels Leslie, la Fleur Susanne E., Boelen Anita One-week exposure to a free-choice high-fat high-sugar diet does not interfere with the lipopolysaccharide-induced acute phase response in the hypothalamus of male rats Frontiers in endocrinology 2018;9 (APR) [PubMed]
  • Eggink Hannah M. Popping the soap bubble: Bile acids as postrandial signal 2018. ISBN 9789402809367. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Romijn J. A., Kalsbeek A.; Co-supervisors: Soeters M. R., Boelen A.)
  • Stroek Kevin, Bouva Marelle J., Schielen Peter C. J. I., Vaz Frédéric M., Heijboer Annemieke C., de Jonge Robert, Boelen Anita, Bosch Annet M. Recommendations for newborn screening for galactokinase deficiency: A systematic review and evaluation of Dutch newborn screening data Molecular genetics and metabolism 2018;124 (1):50-56 [PubMed]
  • van der Spek Anne H., Surovtseva Olga V., Jim Kin Ki, van Oudenaren Adri, Brouwer Matthijs C., Vandenbroucke-Grauls Christina M. J. E., Leenen Pieter J. M., van de Beek Diederik, Hernandez Arturo, Fliers Eric, Boelen Anita Regulation of intracellular triiodothyronine is essential for optimal macrophage function Endocrinology 2018;159 (5):2241-2252 [PubMed]
  • Belegri Evita, Eggels Leslie, Unmehopa Unga A., Mul Joram D., Boelen Anita, la Fleur Susanne E. The effects of overnight nutrient intake on hypothalamic inflammation in a free-choice diet-induced obesity rat model Appetite 2018;120:527-535 [PubMed]
  • van der Spek Anne H. The role of intracellular thyroid hormone metabolism in innate immune cells 2018. ISBN 9789402809800. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Fliers E.; Co-supervisor: Boelen A.)
  • van der Spek Anne H., Jim Kin Ki, Karaczyn Aldona, van Beeren Hermina C., Ackermans Mariëtte T., Darras Veerle M., Vandenbroucke-Grauls Christina M. J. E., Hernandez Arturo, Brouwer Matthijs C., Fliers Eric, van de Beek Diederik, Boelen Anita The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species Endocrinology 2018;159 (2):826-835 [PubMed]
  • Mayerl Steffen, Schmidt Manuel, Doycheva Denica, Darras Veerle M., Hüttner S. ren S., Boelen Anita, Visser Theo J., Kaether Christoph, Heuer Heike, von Maltzahn Julia Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration Stem cell reports 2018;10 (6):1959-1974 [PubMed]
  • Eggink Hannah M., van Nierop F. Samuel, Schooneman Marieke G., Boelen Anita, Kalsbeek Andries, Koehorst Martijn, ten Have Gabriella A. M., de Brauw L. Maurits, Groen Albert K., Romijn Johannes A., Deutz Nicolaas E. P., Soeters Maarten R. Transhepatic bile acid kinetics in pigs and humans Clinical nutrition (Edinburgh, Scotland) 2018;37 (4):1406-1414 [PubMed]
  • Zhang Zhi, Boelen Anita, Kalsbeek Andries, Fliers Eric TRH neurons and thyroid hormone coordinate the hypothalamic response to cold European thyroid journal 2018;7:279-288 [PubMed]

2017

  • Blom Maartje, Pico-Knijnenburg Ingrid, Sijne-van Veen Marja, Boelen Anita, Bredius Robbert G. M., van der Burg Mirjam, Schielen Peter C. J. I. An evaluation of the TREC assay with regard to the integration of SCID screening into the Dutch newborn screening program Clinical immunology (Orlando, Fla.) 2017;180:106-110 [PubMed]
  • Eggink Hannah M., Oosterman Johanneke E., de Goede Paul, de Vries Emmely M., Foppen Ewout, Koehorst Martijn, Groen Albert K., Boelen Anita, Romijn Johannes A., la Fleur Susanne E., Soeters Maarten R., Kalsbeek Andries Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats Chronobiology international 2017;34 (10):1339-1353 [PubMed]
  • Belegri Evita, Rijnsburger Merel, Eggels Leslie, Unmehopa Unga, Scheper Wiep, Boelen Anita, la Fleur Susanne E. Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers Frontiers in neuroscience 2017;11 [PubMed]
  • de Vries E. M., Oosterman J. E., Eggink H. M., de Goede P., Sen S., Foppen E., Boudzovitch-Surovtseva O., Boelen A., Romijn J. A., laFleur S. E., Kalsbeek A. Effects of meal composition and meal timing on the expression of genes involved in hepatic drug metabolism in rats PLoS ONE 2017;12 (10):e0185520 [PubMed]
  • Kemper E. A., Boelen A., Bosch A. M., van Veen-Sijne M., van Rijswijk C. N., Bouva M. J., Fingerhut R., Schielen P. C. J. I. Establishing New Cut-Off Limits for Galactose 1-Phosphate-Uridyltransferase Deficiency for the Dutch Newborn Screening Programme JIMD reports 2017;32:1-6 [PubMed]
  • Zhang Zhi, Boelen Anita, Bisschop Peter H., Kalsbeek Andries, Fliers Eric Hypothalamic effects of thyroid hormone Molecular and cellular endocrinology 2017;458 (C):143-148 [PubMed]
  • Zhang Zhi Hypothalamic regulation of metabolism: Role of thyroid hormone and estrogen 2017. 164p. ISBN 9789463321129. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Fliers E., Kalsbeek A.; Co-supervisors: Bisschop P. H. L. T., Boelen A.)
  • van der Spek Anne H., Surovtseva Olga V., Aan Saskia, Tool Anton T. J., van de Geer Annemarie, Demir Korcan, van Gucht Anja L. M., van Trotsenburg A. S. Paul, van den Berg Timo K., Fliers Eric, Boelen Anita Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor alpha Endocrine connections 2017;6 (8):731-740 [PubMed]
  • Welling Lindsey, Boelen Anita, Derks Terry G. J., Schielen Peter C. J. I., de Vries Maaike, Williams Monique, Wijburg Frits A., Bosch Annet M. Nine years of newborn screening for classical galactosemia in the Netherlands: Effectiveness of screening methods, and identification of patients with previously unreported phenotypes Molecular genetics and metabolism 2017;120 (3):223-228 [PubMed]
  • Roelfsema Ferdinand, Boelen Anita, Kalsbeek Andries, Fliers Eric Regulatory aspects of the human hypothalamus-pituitary-thyroid axis Best practice & research. Clinical endocrinology & metabolism 2017;31 (5 1):487-503 [PubMed]
  • Williams Fiona L. R., Ogston Simon, Hume Robert, Watson Jennifer, Stanbury Kayleigh, Willatts Peter, Boelen Anita, Juszczak Edmund, Brocklehurst Peter Supplemental Iodide for Preterm Infants and Developmental Outcomes at 2 Years: An RCT Pediatrics 2017;139 (5):e20163703 [PubMed]
  • van der Spek Anne H., Fliers Eric, Boelen Anita The classic pathways of thyroid hormone metabolism Molecular and cellular endocrinology 2017;458 (C):29-38 [PubMed]
  • Glynn Nigel, Kenny Helena, Quisenberry Leah, Halsall David J., Cook Paul, Kyaw Tun Tommy, McDermott John H., Smith Diarmuid, Thompson Christopher J., O'Gorman Donal J., Boelen Anita, Lado-Abeal Joaquin, Agha Amar The effect of growth hormone replacement on the thyroid axis in patients with hypopituitarism: in vivo and ex vivo studies Clinical endocrinology 2017;86 (5):747-754 [PubMed]
  • Williams Fiona L. R., Watson Jennifer, Day Chris, Soe Aung, Somisetty Sateesh K., Jackson Lesley, Velten Elena, Boelen Anita Thyroid dysfunction in preterm neonates exposed to iodine Journal of perinatal medicine 2017;45 (1):135-143 [PubMed]
  • van der Spek Anne H., Fliers Eric, Boelen Anita Thyroid hormone metabolism in innate immune cells Journal of endocrinology 2017;232 (2):R67-R81 [PubMed]
  • Boelen Anita, van der Spek Anne H., Bloise Flavia, de Vries Emmely M., Surovtseva Olga V., van Beeren Mieke, Ackermans Mariette T., Kwakkel Joan, Fliers Eric Tissue thyroid hormone metabolism is differentially regulated during illness in mice Journal of endocrinology 2017;233 (1):25-36 [PubMed]

2016

  • Zhang Z., Bisschop P. H., Foppen E., van Beeren H. C., Kalsbeek A., Boelen A., Fliers E. A model for chronic, intrahypothalamic thyroid hormone administration in rats Journal of endocrinology 2016;229 (1):37-45 [PubMed]
  • Heinen Charlotte A., Jongejan Aldo, Watson Peter J., Redeker Bert, Boelen Anita, Boudzovitch-Surovtseva Olga, Forzano Francesca, Hordijk Roel, Kelley Richard, Olney Ann H., Pierpont Mary Ella, Schaefer G. Bradley, Stewart Fiona, van Trotsenburg A. S. Paul, Fliers Eric, Schwabe John W. R., Hennekam Raoul C. A specific mutation in TBL1XR1 causes Pierpont syndrome Journal of medical genetics 2016;53 (5):330-337 [PubMed]
  • Boelen Anita, Ruiter An Fc, Claahsen-van der Grinten Hedi L., Endert Erik, Ackermans Mariette T. Determination of a steroid profile in heel prick blood using LC-MS/MS Bioanalysis 2016;8 (5):375-384 [PubMed]
  • Bloise Flavia F., van der Spek Anne H., Surovtseva Olga V., Ortiga-Carvalho Tania Maria, Fliers Eric, Boelen Anita Differential Effects of Sepsis and Chronic Inflammation on Diaphragm Muscle Fiber Type, Thyroid Hormone Metabolism, and Mitochondrial Function Thyroid 2016;26 (4):600-609 [PubMed]
  • Zhang Z., Liu J., Veldhuis-Vlug A. G., Su Y., Foppen E., van der Eerden B. C. J., Koedam M., Bravenboer N., Kalsbeek A., Boelen A., Fliers E., Bisschop P. H. Effects of Chronic Estrogen Administration in the Ventromedial Nucleus of the Hypothalamus (VMH) on Fat and Bone Metabolism in Ovariectomized Rats Endocrinology 2016;157 (12):4930-4942 [PubMed]
  • de Vries E. M., Lammers L. A., Achterbergh R., Klümpen H.-J., Mathot R. A. A., Boelen A., Romijn J. A. Fasting-Induced Changes in Hepatic P450 Mediated Drug Metabolism Are Largely Independent of the Constitutive Androstane Receptor CAR PLoS ONE 2016;11 (7):e0159552 [PubMed]
  • Zhang Zhi, Foppen Ewout, Su Yan, Bisschop Peter H., Kalsbeek Andries, Fliers Eric, Boelen Anita Metabolic Effects of Chronic T3 Administration in the Hypothalamic Paraventricular and Ventromedial Nucleus in Male Rats Endocrinology 2016;157 (10):4076-4085 [PubMed]
  • Heinen Charlotte A., Losekoot Monique, Sun Yu, Watson Peter J., Fairall Louise, Joustra Sjoerd D., Zwaveling-Soonawala Nitash, Oostdijk Wilma, van den Akker Erica L. T., Alders Mariëlle, Santen Gijs W. E., van Rijn Rick R., Dreschler Wouter A., Surovtseva Olga V., Biermasz Nienke R., Hennekam Raoul C., Wit Jan M., Schwabe John W. R., Boelen Anita, Fliers Eric, van Trotsenburg A. S. Paul Mutations in TBL1X Are Associated With Central Hypothyroidism Journal of clinical endocrinology and metabolism 2016;101 (12):4564-4573 [PubMed]
  • Lammers Laureen A., Achterbergh Roos, Pistorius Marcel C. M., Bijleveld Yuma, de Vries Emmely M., Boelen Anita, Klümpen Heinz-Josef, Romijn Johannes A., Mathôt Ron A. A. Quantitative Method for Simultaneous Analysis of a 5-Probe Cocktail for Cytochrome P450 Enzymes Therapeutic drug monitoring 2016;38 (6):761-768 [PubMed]
  • Rijnsburger Merel, Belegri Evita, Eggels Leslie, Unmehopa Unga A., Boelen Anita, Serlie Mireille J., la Fleur Susanne E. The effect of diet interventions on hypothalamic nutrient sensing pathways in rodents Physiology & behavior 2016;162:61-68 [PubMed]
  • de Vries E. M., Nagel S., Haenold R., Sundaram S. M., Pfrieger F. W., Fliers E., Heuer H., Boelen A. The Role of Hypothalamic NF-κB Signaling in the Response of the HPT-Axis to Acute Inflammation in Female Mice Endocrinology 2016;157 (7):2947-2956 [PubMed]
  • van der Spek Anne H., Bloise Flavia F., Tigchelaar Wikky, Dentice Monica, Salvatore Domenico, van der Wel Nicole N., Fliers Eric, Boelen Anita The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils Endocrinology 2016;157 (8):3293-3305 [PubMed]
  • Visser W. Edward, Bombardieri Cíntia R., Zevenbergen Chantal, Barnhoorn Sander, Ottaviani Alexandre, van der Pluijm Ingrid, Brandt Renata, Kaptein Ellen, van Heerebeek Ramona, van Toor Hans, Garinis George A., Peeters Robin P., Medici Marco, van Ham Willy, Vermeij Wilbert P., de Waard Monique C., de Krijger Ronald R., Boelen Anita, Kwakkel Joan, Kopchick John J., List Edward O., Melis Joost P. M., Darras Veerle M., Dollé Martijn E. T., van der Horst Gijsbertus T. J., Hoeijmakers Jan H. J., Visser Theo J. Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging PLoS ONE 2016;11 (3):e0149941 [PubMed]

2015

  • de Vries E. M., van Beeren H. C., Ackermans M. T., Kalsbeek A., Fliers E., Boelen A. Differential effects of fasting vs food restriction on liver thyroid hormone metabolism in male rats Journal of endocrinology 2015;224 (1):25-35 [PubMed]
  • Lammers Laureen A., Achterbergh Roos, de Vries Emmely M., van Nierop F. Samuel, Klümpen Heinz-Josef, Soeters Maarten R., Boelen Anita, Romijn Johannes A., Mathôt Ron A. A. Short-term fasting alters cytochrome P450-mediated drug metabolism in humans Drug metabolism and disposition: the biological fate of chemicals 2015;43 (6):819-828 [PubMed]
  • Salloum-Asfar Salam, Boelen Anita, Reitsma Pieter H., van Vlijmen Bart J. M. The immediate and late effects of thyroid hormone (triiodothyronine) on murine coagulation gene transcription PLoS ONE 2015;10 (5):e0127469 [PubMed]
  • de Vries Emmely M., Fliers Eric, Boelen Anita The molecular basis of the non-thyroidal illness syndrome Journal of endocrinology 2015;225 (3):R67-R81 [PubMed]
  • Fliers Eric, Bianco Antonio C., Langouche Lies, Boelen Anita Thyroid function in critically ill patients Lancet. Diabetes and endocrinology 2015;3 (10):816-825 [PubMed]
  • de Vries Emmely Marije Thyroid hormone metabolism during inflammation and fasting 2015. 187p. ISBN 9789462595972. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Fliers E., Kalsbeek A.; Co-supervisor: Boelen A.)
  • Bassett J. H. Duncan, van der Spek Anne, Logan John G., Gogakos Apostolos, Bagchi-Chakraborty Jayashree, Murphy Elaine, van Zeijl Clementine, Down Jenny, Croucher Peter I., Boyde Alan, Boelen Anita, Williams Graham R. Thyrostimulin Regulates Osteoblastic Bone Formation During Early Skeletal Development Endocrinology 2015;156 (9):3098-3113 [PubMed]

2014

  • Kwakkel J., Surovtseva O. V., de Vries E. M., Stap J., Fliers E., Boelen A. A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages Endocrinology 2014;155 (7):2725-2734 [PubMed]
  • Herwig Annika, Campbell Gill, Mayer Claus-Dieter, Boelen Anita, Anderson Richard A., Ross Alexander W., Mercer Julian G., Barrett Perry A thyroid hormone challenge in hypothyroid rats identifies t3 regulated genes in the hypothalamus and in models with altered energy balance and glucose homeostasis Thyroid 2014;24 (11):1575-1593 [PubMed]
  • Fliers Eric, Kalsbeek Andries, Boelen Anita Beyond the fixed setpoint of the hypothalamus-pituitary-thyroid axis European journal of endocrinology / European Federation of Endocrine Societies 2014;171 (5):R197-R208 [PubMed]
  • Fliers E., Boelen A., van Trotsenburg A. S. Paul Central regulation of the hypothalamo-pituitary-thyroid (HPT) axis: focus on clinical aspectsin: E. Fliers, M. Korbonits, J. A. Romijn, editors. Handbook of Clinical Neurology Vol.124. Toronto: Elsevier; 2014. p. 127-138
  • de Vries E. M., Eggels L., van Beeren H. C., Ackermans M. T., Kalsbeek A., Fliers E., Boelen A. Fasting-induced changes in hepatic thyroid hormone metabolism in male rats are independent of autonomic nervous input to the liver Endocrinology 2014;155 (12):5033-5041 [PubMed]
  • de Vries E. M., Kwakkel J., Eggels L., Kalsbeek A., Barrett P., Fliers E., Boelen A. NF kappa B Signaling Is Essential for the Lipopolysaccharide-Induced Increase of Type 2 Deiodinase in Tanycytes Endocrinology 2014;155 (5):2000-2008 [PubMed]
  • van Zeijl Clementine J. J., Surovtseva Olga V., Kwakkel Joan, van Beeren Hermina C., Duncan Bassett J. H., Williams Graham R., Wiersinga Wilmar M., Fliers Eric, Boelen Anita Thyrostimulin deficiency does not alter peripheral responses to acute inflammation-induced nonthyroidal illness American journal of physiology. Endocrinology and metabolism 2014;307 (6):E527-E537 [PubMed]
  • Müller Julia, Mayerl Steffen, Visser Theo J., Darras Veerle M., Boelen Anita, Frappart Lucien, Mariotta Luca, Verrey Francois, Heuer Heike Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency Endocrinology 2014;155 (1):315-325 [PubMed]
  • Mayerl Steffen, Müller Julia, Bauer Reinhard, Richert Sarah, Kassmann Celia M., Darras Veerle M., Buder Katrin, Boelen Anita, Visser Theo J., Heuer Heike Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis Journal of clinical investigation 2014;124 (5):1987-1999 [PubMed]

2013

  • Varewijck Aimee J., Boelen Anita, Lamberts Steven W. J., Fliers Eric, Hofland Leo J., Wiersinga Wilmar M., Janssen Joseph A. M. J. L. Circulating IgGs May Modulate IGF-I Receptor Stimulating Activity in a Subset of Patients With Graves' Ophthalmopathy Journal of clinical endocrinology and metabolism 2013;98 (2):769-776 [PubMed]
  • Bisschop P. H., Dekker M. J. H. J., Osterthun W., Kwakkel J., Anink J. J., Boelen A., Unmehopa U. A., Koper J. W., Lamberts S. W. J., Stewart P. M., Swaab D. F., Fliers E. Expression of 11β-hydroxysteroid dehydrogenase type 1 in the human hypothalamus Journal of neuroendocrinology 2013;25 (5):425-432 [PubMed]
  • Langouche Lies, Vander Perre Sarah, Marques Mirna, Boelen Anita, Wouters Pieter J., Casaer Michael P., van den Berghe Greet Impact of Early Nutrient Restriction During Critical Illness on the Nonthyroidal Illness Syndrome and Its Relation With Outcome: A Randomized, Controlled Clinical Study Journal of clinical endocrinology and metabolism 2013;98 (3):1006-1013 [PubMed]
  • Boelen Anita, van Veen Marja, Verkerk Paul H., Diependaal Guido, Loeber Gerard, Elvers Bert, Endert Erik Measuring free thyroxine levels in neonatal heel-prick samples Clinica chimica acta; international journal of clinical chemistry 2013;423:51-55 [PubMed]

2012

  • van Beeren Hermina C., Kwakkel Joan, Ackermans Mariëtte T., Wiersinga Wilmar M., Fliers Eric, Boelen Anita Action of Specific Thyroid Hormone Receptor alpha(1) and beta(1) Antagonists in the Central and Peripheral Regulation of Thyroid Hormone Metabolism in the Rat Thyroid 2012;22 (12):1275-1282 [PubMed]
  • van Zeijl Clementine J. J., van Koppen Chris J., Surovtseva Olga V., de Gooyer Marcel E., Plate Ralf, Conti Paolo, Karstens Willem-Jan, Timmers Marco, Saeed Peerooz, Wiersinga Wilmar M., Miltenburg André M. M., Fliers Eric, Boelen Anita Complete Inhibition of rhTSH-, Graves' Disease IgG-, and M22-Induced cAMP Production in Differentiated Orbital Fibroblasts by a Low-Molecular-Weight TSHR Antagonist Journal of clinical endocrinology and metabolism 2012;97 (5):E781-E785 [PubMed]
  • Ackermans M. T., Kettelarij-Haas Y., Boelen A., Endert E. Determination of thyroid hormones and their metabolites in tissue using SPE UPLC-tandem MS Biomedical chromatography 2012;26 (4):485-490 [PubMed]
  • Louwerens Marloes, Appelhof Bente C., Verloop Herman, Medici Marco, Peeters Robin P., Visser Theo J., Boelen Anita, Fliers Eric, Smit Johannes W. A., Dekkers Olaf M. Fatigue and fatigue-related symptoms in patients treated for different causes of hypothyroidism European journal of endocrinology / European Federation of Endocrine Societies 2012;167 (6):809-815 [PubMed]
  • Boelen Anita, van Beeren Mieke, Vos Xander, Surovtseva Olga, Belegri Evita, Saaltink Dirk-Jan, Vreugdenhil Erno, Kalsbeek Andries, Kwakkel Joan, Fliers Eric Leptin Administration Restores the Fasting-Induced Increase of Hepatic Type 3 Deiodinase Expression in Mice Thyroid 2012;22 (2):192-199 [PubMed]
  • Boelen A., Kwakkel J., Fliers E. Thyroid hormone receptors in health and disease Minerva endocrinologica 2012;37 (4):291-303 [PubMed]

2011

  • van Zeijl C. J. J., Surovtseva O. V., Wiersinga W. M., Fliers E., Boelen A. Acute Inflammation Increases Pituitary and Hypothalamic Glycoprotein Hormone Subunit B5 mRNA Expression in Association with Decreased Thyrotrophin Receptor mRNA Expression in Mice Journal of neuroendocrinology 2011;23 (4):310-319 [PubMed]
  • Boelen Anita, Kwakkel Joan, Fliers Eric Beyond low plasma T3: local thyroid hormone metabolism during inflammation and infection Endocrine reviews 2011;32 (5):670-693 [PubMed]
  • Kwakkel J., Fliers E., Boelen A. Illness-induced changes in thyroid hormone metabolism: focus on the tissue level Netherlands journal of medicine 2011;69 (5):224-228 [PubMed]
  • van Zeijl Clementine J. J. Nonclassical ligands for the thyrotropin receptor. Functional studies on thyrostimulin and Graves' disease immunoglobulins 2011. 189p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Fliers E., Wiersinga W. M.; Co-supervisors: Boelen A., van Koppen C. J.)
  • Soeters M. R., van Zeijl C. J. J., Boelen A., Kloos R., Saeed P., Vriesendorp T. M., Mourits M. P. Optimal management of Graves orbitopathy: a multidisciplinary approach Netherlands journal of medicine 2011;69 (7):302-308 [PubMed]
  • van Zeijl Clementine J. J., Fliers Eric, van Koppen Chris J., Surovtseva Olga V., de Gooyer Marcel E., Mourits Maarten P., Wiersinga Wilmar M., Miltenburg André M. M., Boelen Anita Thyrotropin Receptor-Stimulating Graves' Disease Immunoglobulins Induce Hyaluronan Synthesis by Differentiated Orbital Fibroblasts from Patients with Graves' Ophthalmopathy Not Only Via Cyclic Adenosine Monophosphate Signaling Pathways Thyroid 2011;21 (2):169-176 [PubMed]
  • Boelen A., Endert E. Werkingsmechanismen Hormonenin: A. P. M. Schellekens, editors. Endocrinologie voor analisten. Utrecht: Syntax Media; 2011. p. 19-30, ISBN 9789077423806

2010

  • van Zeijl Clementine J. J., Fliers Eric, van Koppen Chris J., Surovtseva Olga V., de Gooyer Marcel E., Mourits Maarten P., Wiersinga Wilmar M., Miltenburg André M. M., Boelen Anita Effects of Thyrotropin and Thyrotropin-Receptor-Stimulating Graves' Disease Immunoglobulin G on Cyclic Adenosine Monophosphate and Hyaluronan Production in Nondifferentiated Orbital Fibroblasts of Graves' Ophthalmopathy Patients Thyroid 2010;20 (5):535-244 [PubMed]
  • Kwakkel Joan, Chassande Olivier, van Beeren Hermina C., Fliers Eric, Wiersinga Wilmar M., Boelen Anita Thyroid Hormone Receptor alpha Modulates Lipopolysaccharide-Induced Changes in Peripheral Thyroid Hormone Metabolism Endocrinology 2010;151 (4):1959-1969 [PubMed]
  • van Zeijl Clementine J. J., Surovtseva Olga V., Wiersinga Wilmar M., Boelen Anita, Fliers Eric Transient hypothyroxinemia in juvenile glycoprotein hormone subunit B5 knock-out mice Molecular and cellular endocrinology 2010;321 (2):231-238 [PubMed]
  • Fliers Eric, Boelen Anita Type 2 Deiodinase and Brown Fat: The Heat Is On--or Off Endocrinology 2010;151 (9):4087-4089 [PubMed]
  • Kwakkel Gerritdina J. Understanding the non-thyroidal illness syndrome frrom in vivo and iin vitro studies 2010. 189p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wiersinga W. M., Fliers E.; Co-supervisor: Boelen A.)

2009

  • Boelen Anita, Kwakkel Joan, Wieland Catharina W., St Germain Donald L., Fliers Eric, Hernandez Arturo Impaired bacterial clearance in type 3 deiodinase deficient mice infected with Streptococcus pneumoniae Endocrinology 2009;150 (4):1984-1990 [PubMed]
  • Herwig Annika, Wilson Dana, Logie Tracy J., Boelen Anita, Morgan Peter J., Mercer Julian G., Barrett Perry Photoperiod and acute energy deficits interact on components of the thyroid hormone system in hypothalamic tanycytes of the Siberian hamster American journal of physiology. Regulatory, integrative and comparative physiology 2009;296 (5):R1307-R1315 [PubMed]
  • Herwig A., Wilson D., Logie T. J., Boelen A., Morgan P. J., Mercer J. G., Barrett P. Photoperiod and acute energy deficits interact on components of the thyroid hormone system in hypothalamic tanycytes of the Siberian hamster (American Journal of Physiology-Regulatory Integrative and Comparative Physiology (2009) 296, (R1307-R1315) DOI: 10.1152/ajpregu.90755.2008) American journal of physiology. Regulatory, integrative and comparative physiology 2009;297 (5):R1624
  • Kwakkel J., van Beeren H. C., Ackermans M. T., Platvoet-ter Schiphorst M. C., Fliers E., Wiersinga W. M., Boelen A. Skeletal muscle deiodinase type 2 regulation during illness in mice Journal of endocrinology 2009;203 (2):263-270 [PubMed]
  • Klieverik Lars P., Janssen Sarah F., van Riel Annelieke, Foppen Ewout, Bisschop Peter H., Serlie Mireille J., Boelen Anita, Ackermans Mariëtte T., Sauerwein Hans P., Fliers Eric, Kalsbeek Andries Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver Proceedings of the National Academy of Sciences of the United States of America 2009;106 (14):5966-5971 [PubMed]
  • Boelen Anita, Kwakkel Joan, Chassande Olivier, Fliers Eric Thyroid Hormone Receptor beta Mediates Acute Illness-Induced Alterations in Central Thyroid Hormone Metabolism Journal of neuroendocrinology 2009;21 (5):465-472 [PubMed]
  • Boelen Anita Thyroid hormones and glucose metabolism: the story begins before birth Experimental physiology 2009;94 (10):1050-1051 [PubMed]
  • Boelen Anita, Mikita Joanna, Boiziau Claudine, Chassande Olivier, Fliers Eric, Petry Klaus G. Type 3 deiodinase expression in inflammatory spinal cord lesions in rat experimental autoimmune encephalomyelitis Thyroid 2009;19 (12):1401-1406 [PubMed]

2008

  • Klieverik Lars P., Sauerwein Hans P., Ackermans Mariëtte T., Boelen Anita, Kalsbeek Andries, Fliers Eric Effects of thyrotoxicosis and selective hepatic autonomic denervation on hepatic glucose metabolism in rats American journal of physiology. Endocrinology and metabolism 2008;294 (3):E513-E520 [PubMed]
  • Boelen Anita, Wiersinga Wilmar Maarten, Fliers Eric Fasting-induced changes in the hypothalamus-pituitary-thyroid axis Thyroid 2008;18 (2):123-129 [PubMed]
  • Kwakkel J., Chassande O., van Beeren H. C., Wiersinga W. M., Boelen A. Lacking thyroid hormone receptor beta gene does not influence alterations in peripheral thyroid hormone metabolism during acute illness Journal of endocrinology 2008;197 (1):151-158 [PubMed]
  • Boelen Anita, Boorsma Jeffrey, Kwakkel Joan, Wieland Catharina W., Renckens Rosemarijn, Visser Theo J., Fliers Eric, Wiersinga Wilmar M. Type 3 Deiodinase Is Highly Expressed in Infiltrating Neutrophilic Granulocytes in Response to Acute Bacterial Infection Thyroid 2008;18 (10):1095-1103 [PubMed]

2007

  • ten Hoedt A. E., van Kempen A. A., Boelen A., Duran M., Kemper-Proper E. A., Oey-Spauwen M. J. W., Wijburg F. A., Bosch A. M. High incidence of hypermethioninaemia in a single neonatal intensive care unit detected by a newly introduced neonatal screening programme Journal of inherited metabolic disease 2007;30 (6):978 [PubMed]
  • Barrett Perry, Ebling Francis J. P., Schuhler Sandrine, Wilson Dana, Ross Alexander W., Warner Amy, Jethwa Preeti, Boelen Anita, Visser Theo J., Ozanne Daniel M., Archer Zoe A., Mercer Julian G., Morgan Peter J. Hypothalamic thyroid hormone catabolism acts as a gatekeeper for the seasonal control of body weight and reproduction Endocrinology 2007;148 (8):3608-3617 [PubMed]
  • Kwakkel J., Wiersinga W. M., Boelen A. Interleukin-1 beta modulates endogenous thyroid hormone receptor alpha gene transcription in liver cells Journal of endocrinology 2007;194 (2):257-265 [PubMed]
  • Boelen A. Screening op congenitale bijnierschorshyperplasiein: E. P. Krenning, W. M. Wiersinga, Steven W. J. Lamberts, F. Nobels, R. Bouillon, editors. Endocrinologie. S.l.: Elsevier gezondheidszorg; 2007. p. 93, ISBN 9789035229365

2006

  • Boelen A., Kwakkel J., Wiersinga W. M., Fliers E. Chronic local inflammation in mice results in decreased TRH and type 3 deiodinase mRNA expression in the hypothalamic paraventricular nucleus independently of diminished food intake Journal of endocrinology 2006;191 (3):707-714 [PubMed]
  • Boelen A., Wiersinga W. M., Koehrle J. Contributions of cytokines to nonthyroidal illness Current opinion in endocrinology and diabetes 2006;13:444-450
  • Boelen A., Kwakkel J., Vos X. G., Wiersinga W. M., Fliers E. Differential effects of leptin and refeeding on the fasting-induced decrease of pituitary type 2 deiodinase and thyroid hormone receptor beta2 mRNA expression in mice Journal of endocrinology 2006;190 (2):537-544 [PubMed]
  • Kwakkel J., Wiersinga W. M., Boelen A. Differential involvement of nuclear factor-kappaB and activator protein-1 pathways in the interleukin-1beta-mediated decrease of deiodinase type 1 and thyroid hormone receptor beta1 mRNA Journal of endocrinology 2006;189 (1):37-44 [PubMed]

2005

  • Boelen A., Kwakkel J., Alkemade A., Renckens R., Kaptein E., Kuiper G., Wiersinga W. M., Visser T. J. Induction of type 3 deiodinase activity in inflammatory cells of mice with chronic local inflammation Endocrinology 2005;146 (12):5128-5134 [PubMed]

2004

  • Boelen A., Kwakkel J., Platvoet-ter Schiphorst M., Baur A., Köhrle J., Wiersinga W. M. Contribution of interleukin-12 to the pathogenesis of non-thyroidal illness Hormone and metabolic research. Hormon- und Stoffwechselforschung. Hormones et metabolisme 2004;36 (2):101-106 [PubMed]
  • Boelen Anita, Kwakkel Joan, Platvoet-ter Schiphorst Marianne, Mentrup Birgit, Baur Astrid, Koehrle Josef, Wiersinga Wilmar M. Interleukin-18, a proinflammatory cytokine, contributes to the pathogenesis of non-thyroidal illness mainly via the central part of the hypothalamus-pituitary-thyroid axis European journal of endocrinology / European Federation of Endocrine Societies 2004;151 (4):497-502 [PubMed]
  • Barends M., de Rond L. G. H., Dormans J., van Oosten M., Boelen A., Neijens H. J., Osterhaus A. D. M. E., Kimman T. G. Respiratory syncytial virus, pneumonia virus of mice, and influenza A virus differently affect respiratory allergy in mice Clinical and experimental allergy 2004;34 (3):488-496 [PubMed]
  • Boelen A., Kwakkel J., Thijssen-Timmer D. C., Alkemade A., Fliers E., Wiersinga W. M. Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice Journal of endocrinology 2004;182 (2):315-323 [PubMed]

2003

  • Barends Marion, Boelen Anita, de Rond Lia, Dormans Jan, Kwakkel Joan, van Oosten Marijke, Neijens Herman J., Kimman Tjeerd G. Respiratory syncytial virus enhances respiratory allergy in mice despite the inhibitory effect of virus-induced interferon-gamma Journal of medical virology 2003;69 (1):156-162 [PubMed]

2002

  • Boelen Anita, Kwakkel Joan, Barends Marion, de Rond Lia, Dormans Jan, Kimman Tjeerd Effect of lack of Interleukin-4, Interleukin-12, Interleukin-18, or the Interferon-gamma receptor on virus replication, cytokine response, and lung pathology during respiratory syncytial virus infection in mice Journal of medical virology 2002;66 (4):552-560 [PubMed]
  • Barends M., Boelen A., de Rond L., Kwakkel J., Bestebroer T., Dormans J., Neijens H., Kimman T. Influence of respiratory syncytial virus infection on cytokine and inflammatory responses in allergic mice Clinical and experimental allergy 2002;32 (3):463-471 [PubMed]

2000

  • Boelen A., Andeweg A., Kwakkel J., Lokhorst W., Bestebroer T., Dormans J., Kimman T. Both immunisation with a formalin-inactivated respiratory syncytial virus (RSV) vaccine and a mock antigen vaccine induce severe lung pathology and a Th2 cytokine profile in RSV-challenged mice Vaccine 2000;19 (7-8):982-991 [PubMed]

1997

  • Boelen A., Platvoet-ter Schiphorst M. C., Wiersinga W. M. Immunoneutralization of interleukin-1, tumor necrosis factor, interleukin-6 or interferon does not prevent the LPS-induced sick euthyroid syndrome in mice Journal of endocrinology 1997;153 (1):115-122 [PubMed]

1996

  • Boelen A., Maas M. A., Lowik C. W., Platvoet M. C., Wiersinga W. M. Induced illness in interleukin-6 (IL-6) knock-out mice: a causal role of IL-6 in the development of the low 3,5,3'-triiodothyronine syndrome Endocrinology 1996;137 (12):5250-5254 [PubMed]
  • Boelen A., Schiphorst M. C., Wiersinga W. M. Relationship between serum 3,5,3'-triiodothyronine and serum interleukin-8, interleukin-10 or interferon gamma in patients with nonthyroidal illness Journal of endocrinological investigation 1996;19 (7):480-483 [PubMed]
  • Boelen A., Platvoet-ter Schiphorst M. C., van Rooijen N., Wiersinga W. M. Selective macrophage depletion in the liver does not prevent the development of the sick euthyroid syndrome in the mouse European journal of endocrinology / European Federation of Endocrine Societies 1996;134 (4):513-518 [PubMed]

1995

  • Boelen A., Platvoet-ter Schiphorst M. C., Wiersinga W. M. Soluble cytokine receptors and the low 3,5,3'-triiodothyronine syndrome in patients with nonthyroidal disease Journal of clinical endocrinology and metabolism 1995;80 (3):971-976 [PubMed]
  • Boelen A., Platvoet-ter Schiphorst M. C., Bakker O., Wiersinga W. M. The role of cytokines in the lipopolysaccharide-induced sick euthyroid syndrome in mice Journal of endocrinology 1995;146 (3):475-483 [PubMed]

1994

  • DeRijk R. H., Boelen A., Tilders F. J., Berkenbosch F. Induction of plasma interleukin-6 by circulating adrenaline in the rat Psychoneuroendocrinology 1994;19 (2):155-163 [PubMed]

1993

  • Boelen A., Platvoet-ter Schiphorst M. C., Wiersinga W. M. Association between serum interleukin-6 and serum 3,5,3'-triiodothyronine in nonthyroidal illness Journal of clinical endocrinology and metabolism 1993;77 (6):1695-1699 [PubMed]