Prof. MD PhD G.K. Hovingh publications

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Publications Prof. MD PhD G.K. Hovingh

Position
Full Professor
Main activities
Education, Patient care, Research, Other
Specialisation
Lipid metabolism, Genetics
Focus of research
The focus of my research is the molecular basis of inherited dyslipidemias and novel therapies.

2020

  • Reeskamp Laurens F., Volta Andrea, Zuurbier Linda, Defesche Joep C., Hovingh G. Kees, Grefhorst Aldo ABCG5 and ABCG8 genetic variants in familial hypercholesterolemia Journal of clinical lipidology 2020 [PubMed]
  • Santos Raul D., Stein Evan A., Hovingh G. Kees, Blom Dirk J., Soran Handrean, Watts Gerald F., López J. Antonio G., Bray Sarah, Kurtz Christopher E., Hamer Andrew W., Raal Frederick J. Long-Term Evolocumab in Patients With Familial Hypercholesterolemia Journal of the American College of Cardiology 2020;75 (6):565-574 [PubMed]
  • Bruikman Caroline S., Vreeken Dianne, Hoogeveen Renate M., Bom Michiel J., Danad Ibrahim, Pinto-Sietsma Sara-Joan, van Zonneveld Anton Jan, Knaapen Paul, Hovingh G. Kees, Stroes Erik S. G., van Gils Janine M. Netrin-1 and the Grade of Atherosclerosis Are Inversely Correlated in Humans Arteriosclerosis, thrombosis, and vascular biology 2020;40 (2):462-472 [PubMed]
  • Hegele Robert A., Borén Jan, Ginsberg Henry N., Arca Marcello, Averna Maurizio, Binder Christoph J., Calabresi Laura, Chapman M. John, Cuchel Marina, von Eckardstein Arnold, Frikke-Schmidt Ruth, Gaudet Daniel, Hovingh G. Kees, Kronenberg Florian, Lütjohann Dieter, Parhofer Klaus G., Raal Frederick J., Ray Kausik K., Remaley Alan T., Stock Jane K., Stroes Erik S., Tokgözoğlu Lale, Catapano Alberico L. Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement Lancet. Diabetes and endocrinology 2020;8 (1):50-67 [PubMed]
  • Hemphill Linda, Goldberg Anne, Hovingh Kees, Cohen Jerome, Karalis Dean G. Recognition and Treatment of Homozygous Familial Hypercholesterolemia by Primary Care Physicians: a Survey from the National Lipid Association Journal of general internal medicine 2020 [PubMed]
  • Wilemon Katherine A., Patel Jasmine, Aguilar-Salinas Carlos, Ahmed Catherine D., Alkhnifsawi Mutaz, Almahmeed Wael, Alonso Rodrigo, Al-Rasadi Khalid, Badimon Lina, Bernal Luz M., Bogsrud Martin P., Braun Lynne T., Brunham Liam, Catapano Alberico L., Čillíková Kristyna, Corral Pablo, Cuevas Regina, Defesche Joep C., Descamps Olivier S., de Ferranti Sarah, Eiselé Jean-Luc, Elikir Gerardo, Folco Emanuela, Freiberger Tomas, Fuggetta Francesco, Gaspar Isabel M., Gesztes Ákos G., Grošelj Urh, Hamilton-Craig Ian, Hanauer-Mader Gabriele, Harada-Shiba Mariko, Hastings Gloria, Hovingh G. Kees, Izar Maria C., Jamison Allison, Karlsson Gunnar N., Kayikçioǧlu Meral, Koob Sue, Koseki Masahiro, Lane Stacey, Lima-Martinez Marcos M., López Greizy, Martinez Tania L., Marais David, Marion Letrillart, Mata Pedro, Maurina Inese, Maxwell Diana, Mehta Roopa, Mensah George A., Miserez André R., Neely Dermot, Nicholls Stephen J., Nohara Atsushi, Nordestgaard B. rge G., Ose Leiv, Pallidis Athanasios, Pang Jing, Payne Jules, Peterson Amy L., Popescu Monica P., Puri Raman, Ray Kausik K., Reda Ashraf, Sampietro Tiziana, Santos Raul D., Schalkers Inge, Schreier Laura, Shapiro Michael D., Sijbrands Eric, Soffer Daniel, Stefanutti Claudia, Stoll Mario, Sy Rody G., Tamayo Martha L., Tilney Myra K., Tokgözoǧlu Lale, Tomlinson Brian, Vallejo-Vaz Antonio J., Vazquez-Cárdenas Alejandra, de Luca Patrícia Vieira, Wald David S., Watts Gerald F., Wenger Nanette K., Wolf Michaela, Wood David, Zegerius Aram, Gaziano Thomas A., Gidding Samuel S. Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action JAMA cardiology 2020;5 (2):217-229 [PubMed]
  • Bruikman Caroline, de Ronde Maurice W. J., Amin Ahmed, Levy Sonja, Lof Pien, de Ruijter Ursula, Hovingh Kees, Tan Hanno L., Pinto-Sietsma Sara-Joan Sudden cardiac death in families with premature cardiovascular disease Heart (British Cardiac Society) 2020;106 (3):228-232 [PubMed]
  • Loaiza Natalia, Hartgers Merel L., Reeskamp Laurens F., Balder Jan-Willem, Rimbert Antoine, Bazioti Venetia, Wolters Justina C., Winkelmeijer Maaike, Jansen Hans P. G., Dallinga-Thie Geesje M., Volta Andrea, Huijkman Nicolette, Smit Marieke, Kloosterhuis Niels, Koster Mirjam, Svendsen Arthur F., van de Sluis Bart, Hovingh G. Kees, Grefhorst Aldo, Kuivenhoven Jan Albert Taking One Step Back in Familial Hypercholesterolemia: STAP1 Does Not Alter Plasma LDL (Low-Density Lipoprotein) Cholesterol in Mice and Humans Arteriosclerosis, thrombosis, and vascular biology 2020;40 (4):973-985 [PubMed]
  • Bruikman Caroline S., Vreeken Dianne, Zhang Huayu, van Gils Marit J., Peter Jorge, van Zonneveld Anton Jan, Hovingh G. Kees, van Gils Janine M. The identification and function of a Netrin-1 mutation in a pedigree with premature atherosclerosis Atherosclerosis 2020 [PubMed]

2019

  • Patel Riyaz S., Schmidt Amand F., Tragante Vinicius, McCubrey Raymond O., Holmes Michael V., Howe Laurence J., Direk Kenan, Åkerblom Axel, Leander Karin, Virani Salim S., Kaminski Karol A., Muehlschlegel Jochen D., Dubé Marie Pierre, Allayee Hooman, Almgren Peter, Alver Maris, Baranova Ekaterina V., Behlouli Hassan, Boeckx Bram, Braund Peter S., Breitling Lutz P., Delgado Graciela, Duarte Nubia E., Dufresne Line, Eriksson Niclas, Foco Luisa, Gijsberts Crystel M., Gong Yan, Hartiala Jaana, Heydarpour Mahyar, Hubacek Jaroslav A., Kleber Marcus, Kofink Daniel, Kuukasjärvi Pekka, Lee Vei Vei, Leiherer Andreas, Lenzini Petra A., Levin Daniel, Lyytikäinen Leo Pekka, Martinelli Nicola, Mons Ute, Nelson Christopher P., Nikus Kjell, Pilbrow Anna P., Ploski Rafal, Tanck Michael W.T., Wilde Arthur A.M., Bezzina Connie R., Hovingh G. Kees, Maitland-Van der Zee Anke H. Association of chromosome 9p21 with subsequent coronary heart disease events: A GENIUS-CHD study of individual participant data Circulation. Genomic and precision medicine 2019;12 (4):161-172 [PubMed]
  • Ference Brian A., Bhatt Deepak L., Catapano Alberico L., Packard Chris J., Graham Ian, Kaptoge Stephen, Ference Thatcher B., Guo Qi, Laufs Ulrich, Ruff Christian T., Cupido Arjen, Hovingh G. Kees, Danesh John, Holmes Michael V., Smith George Davey, Ray Kausik K., Nicholls Stephen J., Sabatine Marc S. Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure with Lifetime Risk of Cardiovascular Disease JAMA 2019;322 (14):1381-1391 [PubMed]
  • Vogt Liffert, Bangalore Sripal, Fayyad Rana, Melamed Shari, Hovingh G. Kees, DeMicco David A., Waters David D. Atorvastatin Has a Dose-Dependent Beneficial Effect on Kidney Function and Associated Cardiovascular Outcomes: Post Hoc Analysis of 6 Double-Blind Randomized Controlled Trials Journal of the American Heart Association 2019;8 (9):e010827 [PubMed]
  • van Velzen Daan M., Paldino Alessia, Klaver Maartje, Nota Nienke M., Defreyne Justine, Hovingh G. Kees, Thijs Abel, Simsek Suat, t'Sjoen Guy, den Heijer Martin Cardiometabolic Effects of Testosterone in Transmen and Estrogen Plus Cyproterone Acetate in Transwomen Journal of clinical endocrinology and metabolism 2019;104 (6):1937-1947 [PubMed]
  • Stoekenbroek R.M. High risk cardiovascular disease: From insight to therapy 2019. 204p. ISBN 9789463756068. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Hovingh G.K., Legemate D.A.; Co-supervisors: Koelemaij M.J.W., Ubbink D.T.)
  • Hovingh G. Kees, Reeskamp Laurens F., Ray Kausik K. Hypercholesterolemia Among Premature Infarcts: Time to Start the Clock of Familial Hypercholesterolemia Assessment Journal of the American College of Cardiology 2019;73 (19):2451-2453 [PubMed]
  • Ginsberg Henry N., Tuomilehto Jaakko, Hovingh G. Kees, Cariou Bertrand, Santos Raul D., Brown Alan S., Sanganalmath Santosh K., Koren Andrew, Thompson Desmond, Raal Frederick J. Impact of Age on the Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2019 [PubMed]
  • Dufour Robert, Hovingh G. Kees, Guyton John R., Langslet Gisle, Baccara-Dinet Marie T., Din-Bell Chantal, Manvelian Garen, Farnier Michel Individualized low-density lipoprotein cholesterol reduction with alirocumab titration strategy in heterozygous familial hypercholesterolemia: Results from an open-label extension of the ODYSSEY LONG TERM trial Journal of clinical lipidology 2019;13 (1):138-147 [PubMed]
  • Verbeek Rutger Lp(a) and PCSK9: From concept to clinical practice 2019. 169p. ISBN 9789463756235. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Hovingh G. K. , Stroes E. S. G.; Co-supervisor: Boekholdt S. M.)
  • Aman Jurjan, Kees Hovingh G. Multilevel omics: A next step on the way to understanding pulmonary arterial hypertension? Thorax 2019;74 (4):317-318 [PubMed]
  • Stols-Gonçalves Daniela, Hovingh G. Kees, Nieuwdorp Max, Holleboom Adriaan G. NAFLD and Atherosclerosis: Two Sides of the Same Dysmetabolic Coin? Trends in endocrinology and metabolism: TEM 2019 [PubMed]
  • Reeskamp Laurens F., R Tromp Tycho, Hovingh G. Kees PCSK9 as predictor for recurrent cardiovascular disease in familial hypercholesterolemia European journal of preventive cardiology 2019 [PubMed]
  • Schmidt Amand F., Holmes Michael V., Preiss David, Swerdlow Daniel I., Denaxas Spiros, Fatemifar Ghazaleh, Faraway Rupert, Finan Chris, Valentine Dennis, Fairhurst-Hunter Zammy, Hartwig Fernando Pires, Horta Bernardo Lessa, Hypponen Elina, Power Christine, Moldovan Max, van Iperen Erik, Hovingh Kees, Demuth Ilja, Norman Kristina, Steinhagen-Thiessen Elisabeth, Demuth Juri, Bertram Lars, Lill Christina M., Coassin Stefan, Willeit Johann, Kiechl Stefan, Willeit Karin, Mason Dan, Wright John, Morris Richard, Wanamethee Goya, Whincup Peter, Ben-Shlomo Yoav, McLachlan Stela, Price Jackie F., Kivimaki Mika, Welch Catherine, Sanchez-Galvez Adelaida, Marques-Vidal Pedro, Nicolaides Andrew, Panayiotou Andrie G., Onland-Moret N. Charlotte, van der Schouw Yvonne T., Matullo Giuseppe, Fiorito Giovanni, Guarrera Simonetta, Sacerdote Carlotta, Wareham Nicholas J., Langenberg Claudia, Scott Robert A., Luan Jian'An, Bobak Martin, Malyutina Sofia, Pajak Andrzej, Kubinova Ruzena, Tamosiunas Abdonas, Pikhart Hynek, Grarup Niels, Pedersen Oluf, Hansen Torben, Linneberg Allan, Jess Tine, Cooper Jackie, Humphries Steve E., Brilliant Murray, Kitchner Terrie, Hakonarson Hakon, Carrell David S., McCarty Catherine A., Lester Kirchner H., Larson Eric B., Crosslin David R., de Andrade Mariza, Roden Dan M., Denny Joshua C., Carty Cara, Hancock Stephen, Attia John, Holliday Elizabeth, Scott Rodney, Schofield Peter, O'Donnell Martin, Yusuf Salim, Chong Michael, Pare Guillaume, van der Harst Pim, Said M. Abdullah, Eppinga Ruben N., Verweij Niek, Snieder Harold, Christen Tim, Mook-Kanamori D. O., Gustafsson Stefan, Lind Lars, Ingelsson Erik, Pazoki Raha, Franco Oscar, Hofman Albert, Uitterlinden Andre, Dehghan Abbas, Teumer Alexander, Baumeister Sebastian, Dörr Marcus, Lerch Markus M., Völker Uwe, Völzke Henry, Ward Joey, Pell Jill P., Meade Tom, Christophersen Ingrid E., Maitland-van der Zee Anke H., Baranova Ekaterina V., Young Robin, Ford Ian, Campbell Archie, Padmanabhan Sandosh, Bots Michiel L., Grobbee Diederick E., Froguel Philippe, Thuillier Dorothée, Roussel Ronan, Bonnefond Amélie, Cariou Bertrand, Smart Melissa, Bao Yanchun, Kumari Meena, Mahajan Anubha, Hopewell Jemma C., Seshadri Sudha, Dale Caroline, Costa Rui Providencia E., Ridker Paul M., Chasman Daniel I., Reiner Alex P., Ritchie Marylyn D., Lange Leslie A., Cornish Alex J., Dobbins Sara E., Hemminki Kari, Kinnersley Ben, Sanson Marc, Labreche Karim, Simon Matthias, Bondy Melissa, Law Philip, Speedy Helen, Allan James, Li Ni, Went Molly, Weinhold Niels, Morgan Gareth, Sonneveld Pieter, Nilsson Björn, Goldschmidt Hartmut, Sud Amit, Engert Andreas, Hansson Markus, Hemingway Harry, Asselbergs Folkert W., Patel Riyaz S., Keating Brendan J., Sattar Naveed, Houlston Richard, Casas Juan P., Hingorani Aroon D. Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 BMC cardiovascular disorders 2019;19 (1) [PubMed]
  • Justice Anne E., Karaderi Tugce, Highland Heather M., Young Kristin L., Graff Mariaelisa, Lu Yingchang, Turcot Valérie, Auer Paul L., Fine Rebecca S., Guo Xiuqing, Schurmann Claudia, Lempradl Adelheid, Marouli Eirini, Mahajan Anubha, Winkler Thomas W., Locke Adam E., Medina-Gomez Carolina, Esko T. nu, Vedantam Sailaja, Giri Ayush, Lo Ken Sin, Alfred Tamuno, Mudgal Poorva, Ng Maggie C. Y., Heard-Costa Nancy L., Feitosa Mary F., Manning Alisa K., Willems Sara M., Sivapalaratnam Suthesh, Abecasis Goncalo, Alam Dewan S., Allison Matthew, Amouyel Philippe, Arzumanyan Zorayr, Balkau Beverley, Bastarache Lisa, Bergmann Sven, Bielak Lawrence F., Blüher Matthias, Boehnke Michael, Boeing Heiner, Boerwinkle Eric, Böger Carsten A., Bork-Jensen Jette, Bottinger Erwin P., Bowden Donald W., Brandslund Ivan, Broer Linda, Burt Amber A., Hovingh G. Kees, Adrienne Cupples L., North Kari E., Lindgren Cecilia M. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution Nature genetics 2019;51 (3):452-469 [PubMed]
  • Turcot Valérie, Lu Yingchang, Highland Heather M., Schurmann Claudia, Justice Anne E., Fine Rebecca S., Bradfield Jonathan P., Esko T. nu, Giri Ayush, Graff Mariaelisa, Guo Xiuqing, Hendricks Audrey E., Karaderi Tugce, Lempradl Adelheid, Locke Adam E., Mahajan Anubha, Marouli Eirini, Sivapalaratnam Suthesh, Young Kristin L., Alfred Tamuno, Feitosa Mary F., Masca Nicholas G. D., Manning Alisa K., Medina-Gomez Carolina, Mudgal Poorva, Ng Maggie C. Y., Reiner Alex P., Vedantam Sailaja, Willems Sara M., Winkler Thomas W., Abecasis Gonçalo, Aben Katja K., Alam Dewan S., Alharthi Sameer E., Allison Matthew, Amouyel Philippe, Asselbergs Folkert W., Auer Paul L., Balkau Beverley, Bang Lia E., Barroso Inês, Bastarache Lisa, Benn Marianne, Bergmann Sven, Bielak Lawrence F., Blüher Matthias, Boehnke Michael, Boeing Heiner, Boerwinkle Eric, Hovingh G. Kees, North Kari E., Lindgren Cecilia M., Hirschhorn Joel N., Loos Ruth J. F. Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x) Nature genetics 2019;51 (7):1191-1192 [PubMed]
  • Patel Riyaz S., Tragante Vinicius, Schmidt Amand F., McCubrey Raymond O., Holmes Michael V., Howe Laurence J., Direk Kenan, Åkerblom Axel, Leander Karin, Virani Salim S., Kaminski Karol A., Muehlschlegel Jochen D., Allayee Hooman, Almgren Peter, Alver Maris, Baranova Ekaterina V., Behloui Hassan, Boeckx Bram, Braund Peter S., Breitling Lutz P., Delgado Graciela, Duarte Nubia E., Dubé Marie-Pierre, Dufresne Line, Eriksson Niclas, Foco Luisa, Scholz Markus, Gijsberts Crystel M., Glinge Charlotte, Gong Yan, Hartiala Jaana, Heydarpour Mahyar, Hubacek Jaroslav A., Kleber Marcus, Kofink Daniel, Kotti Salma, Kuukasjärvi Pekka, Lee Vei-Vei, Leiherer Andreas, Lenzini Petra A., Levin Daniel, Lyytikäinen Leo-Pekka, Martinelli Nicola, Mons Ute, Nelson Christopher P., Nikus Kjell, Pilbrow Anna P., Ploski Rafal, Sun Yan V., Tanck Michael W. T., Tang W. H. Wilson, Trompet Stella, van der Laan Sander W., van Setten Jessica, Vilmundarson Ragnar O., Viviani Anselmi Chiara, Vlachopoulou Efthymia, Al Ali Lawien, Boerwinkle Eric, Briguori Carlo, Carlquist John F., Carruthers Kathryn F., Casu Gavino, Deanfield John, Deloukas Panos, Dudbridge Frank, Engstrøm Thomas, Fitzpatrick Natalie, Fox Kim, Gigante Bruna, James Stefan, Lokki Marja-Liisa, Lotufo Paulo A., Marziliano Nicola, Mordi Ify R., Muhlestein Joseph B., Newton-Cheh Christopher, Pitha Jan, Saely Christoph H., Samman-Tahhan Ayman, Sandesara Pratik B., Teren Andrej, Timmis Adam, van de Werf Frans, Wauters Els, Wilde Arthur A. M., Ford Ian, Stott David J., Algra Ale, Andreassi Maria G., Ardissino Diego, Arsenault Benoit J., Ballantyne Christie M., Bergmeijer Thomas O., Bezzina Connie R., Body Simon C., Boersma Eric H., Bogaty Peter, Bots Michiel L., Brenner Hermann, Brugts Jasper J., Burkhardt Ralph, Carpeggiani Clara, Condorelli Gianluigi, Cooper-DeHoff Rhonda M., Cresci Sharon, Danchin Nicolas, de Faire Ulf, Doughty Robert N., Drexel Heinz, Engert James C., Fox Keith A. A., Girelli Domenico, Grobbee Diederick E., Hagström Emil, Hazen Stanley L., Held Claes, Hemingway Harry, Hoefer Imo E., Hovingh G. Kees, Jabbari Reza, Johnson Julie A., Jukema J. Wouter, Kaczor Marcin P., Kähönen Mika, Kettner Jiri, Kiliszek Marek, Klungel Olaf H., Lagerqvist Bo, Lambrechts Diether, Laurikka Jari O., Lehtimäki Terho, Lindholm Daniel, Mahmoodi B. K., Maitland-van der Zee Anke H., McPherson Ruth, Melander Olle, Metspalu Andres, Niemcunowicz-Janica Anna, Olivieri Oliviero, Opolski Grzegorz, Palmer Colin N., Pasterkamp Gerard, Pepine Carl J., Pereira Alexandre C., Pilote Louise, Quyyumi Arshed A., Richards A. Mark, Sanak Marek, Siegbahn Agneta, Simon Tabassome, Sinisalo Juha, Smith J. Gustav, Spertus John A., Stender Steen, Stewart Alexandre F. R., Szczeklik Wojciech, Szpakowicz Anna, Tardif Jean-Claude, ten Berg Jurriën M., Tfelt-Hansen Jacob, Thanassoulis George, Thiery Joachim, Torp-Pedersen Christian, van der Graaf Yolanda, Visseren Frank L. J., Waltenberger Johannes, Weeke Peter E., van der Harst Pim, Lang Chim C., Sattar Naveed, Cameron Vicky A., Anderson Jeffrey L., Brophy James M., Pare Guillaume, Horne Benjamin D., März Winfried, Wallentin Lars, Samani Nilesh J., Hingorani Aroon D., Asselbergs Folkert W. Subsequent Event Risk in Individuals With Established Coronary Heart Disease Circulation. Genomic and precision medicine 2019;12 (4):e002470 [PubMed]
  • Luirink Ilse K., Braamskamp Marjet J. A. M., Wiegman Albert, Hartgers Merel L., Sjouke Barbara, Defesche Joep C., Hovingh G. Kees The clinical and molecular diversity of homozygous familial hypercholesterolemia in children: Results from the GeneTics of clinical homozygous hypercholesterolemia (GoTCHA)study Journal of clinical lipidology 2019;13 (2):272-278 [PubMed]

2018

  • Landmesser Ulf, Chapman M. John, Stock Jane K., Amarenco Pierre, Belch Jill J. F., Borén Jan, Farnier Michel, Ference Brian A., Gielen Stephan, Graham Ian, Grobbee Diederick E., Hovingh G. Kees, Lüscher Thomas F., Piepoli Massimo F., Ray Kausik K., Stroes Erik S., Wiklund Olov, Windecker Stephan, Zamorano Jose Luis, Pinto Fausto, Tokgözoglu Lale, Bax Jeroen J., Catapano Alberico L. 2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein convertase subtilisin/kexin type 9 inhibition in patients with atherosclerotic cardiovascular disease or in familial hypercholesterolaemia European heart journal 2018;39 (14):1131–1143 [PubMed]
  • Hartgers Merel L., Besseling Joost, Stroes Erik S., Wittekoek Janneke, Rutten Joost H. W., de Graaf Jacqueline, Visseren Frank L. J., Imholz Ben P. M., Roeters van Lennep Jeanine E., Huijgen Roeland, Kastelein John J. P., Hovingh G. Kees Achieved LDL cholesterol levels in patients with heterozygous familial hypercholesterolemia: A model that explores the efficacy of conventional and novel lipid-lowering therapy Journal of clinical lipidology 2018;12 (4):972-980.e1 [PubMed]
  • Hovingh G. Kees, Guyton John R., Langslet Gisle, Dufour Robert, Baccara-Dinet Marie T., Din-Bell Chantal, Manvelian Garen, Farnier Michel Alirocumab dosing patterns during 40 months of open-label treatment in patients with heterozygous familial hypercholesterolemia Journal of clinical lipidology 2018;12 (6):1463-1470 [PubMed]
  • Bays Harold E., Rosenson Robert S., Baccara-Dinet Marie T., Louie Michael J., Thompson Desmond, Hovingh G. Kees Assessment of the 1% of Patients with Consistent < 15% Reduction in Low-Density Lipoprotein Cholesterol: Pooled Analysis of 10 Phase 3 ODYSSEY Alirocumab Trials Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2018;32 (2):175-180 [PubMed]
  • Verbeek Rutger, Hoogeveen Renate M, Langsted Anne, Stiekema Lotte C A, Verweij Simone L, Hovingh G Kees, Wareham Nicholas J, Khaw Kay-Tee, Boekholdt S Matthijs, Nordestgaard Børge G, Stroes Erik S G Cardiovascular disease risk associated with elevated lipoprotein(a) attenuates at low low-density lipoprotein cholesterol levels in a primary prevention setting European heart journal 2018;39 (27):2589-2596 [PubMed]
  • Sturm Amy C., Knowles Joshua W., Gidding Samuel S., Ahmad Zahid S., Ahmed Catherine D., Ballantyne Christie M., Baum Seth J., Bourbon Mafalda, Carrié Alain, Cuchel Marina, de Ferranti Sarah D., Defesche Joep C., Freiberger Tomas, Hershberger Ray E., Hovingh G. Kees, Karayan Lala, Kastelein Johannes Jacob Pieter, Kindt Iris, Lane Stacey R., Leigh Sarah E., Linton MacRae F., Mata Pedro, Neal William A., Nordestgaard B. rge G., Santos Raul D., Harada-Shiba Mariko, Sijbrands Eric J., Stitziel Nathan O., Yamashita Shizuya, Wilemon Katherine A., Ledbetter David H., Rader Daniel J. Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel Journal of the American College of Cardiology 2018;72 (6):662-680 [PubMed]
  • Oldoni Federico, Baldassarre Damiano, Castelnuovo Samuela, Ossoli Alice, Amato Mauro, van Capelleveen Julian, Hovingh G. Kees, de Groot Eric, Bochem Andrea, Simonelli Sara, Barbieri Simone, Veglia Fabrizio, Franceschini Guido, Kuivenhoven Jan Albert, Holleboom Adriaan G., Calabresi Laura Complete and Partial Lecithin:Cholesterol Acyltransferase Deficiency Is Differentially Associated With Atherosclerosis Circulation 2018;138 (10):1000-1007 [PubMed]
  • Bays Harold E., Rosenson Robert S., Baccara-Dinet Marie T., Louie Michael J., Thompson Desmond, Kees Hovingh G. Correction to: Assessment of the 1% of Patients with Consistent < 15% Reduction in Low-Density Lipoprotein Cholesterol: Pooled Analysis of 10 Phase 3 ODYSSEY Alirocumab Trials (Cardiovasc Drugs Ther, 10.1007/s10557-018-6784-z) Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2018;32 (2):181 [PubMed]
  • Arsenault Benoit J., Petrides Francine, Tabet Fatiha, Bao Weihang, Hovingh G. Kees, Boekholdt S. Matthijs, Ramin-Mangata Stéphane, Meilhac Olivier, DeMicco David, Rye Kerry-Anne, Waters David D., Kastelein John J. P., Barter Philip, Lambert Gilles Effect of atorvastatin, cholesterol ester transfer protein inhibition, and diabetes mellitus on circulating proprotein subtilisin kexin type 9 and lipoprotein(a) levels in patients at high cardiovascular risk Journal of clinical lipidology 2018;12 (1):130-136 [PubMed]
  • Verbeek Rutger, Boekholdt S. Matthijs, Luben Robert, Stroes Erik S. G., Khaw Kay-Tee, Hovingh G. Kees Effect of Long-Term Low Lipoproteins on Neurocognitive Function Journal of the American College of Cardiology 2018;72 (10):1176-1177 [PubMed]
  • Harada-Shiba Mariko, Kastelein John J. P., Hovingh G. Kees, Ray Kausik K., Ohtake Akira, Arisaka Osamu, Ohta Takao, Okada Tomoo, Suganami Hideki, Wiegman Albert Efficacy and Safety of Pitavastatin in Children and Adolescents with Familial Hypercholesterolemia in Japan and Europe Journal of atherosclerosis and thrombosis 2018;25 (5):422-429 [PubMed]
  • Gazzola Katia, Snijder Marieke B., Hovingh G. Kees, Stroes Erik S. G., Peters Ron J. G., van den Born Bert-Jan H. Ethnic differences in plasma lipid levels in a large multiethnic cohort: The HELIUS study Journal of clinical lipidology 2018;12 (5):1217-1224.e1 [PubMed]
  • Raal Frederick J., Hovingh G. Kees, Catapano Alberico L. Familial hypercholesterolemia treatments: Guidelines and new therapies Atherosclerosis 2018;277:483-492 [PubMed]
  • van Iperen Erik P. A. Genetic risk factors of cardiovascular disease 2018. ISBN 9789463750905. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Zwinderman A. H., Asselbergs F. W.; Co-supervisor: Hovingh G. K.)
  • Volta Andrea, Hovingh G. Kees, Grefhorst Aldo Genetics of familial hypercholesterolemia: a tool for development of novel lipid lowering pharmaceuticals? Current opinion in lipidology 2018;29 (2):80-86 [PubMed]
  • Stoekenbroek Robert M., Lambert Gilles, Cariou Bertrand, Hovingh G. Kees Inhibiting PCSK9 — biology beyond LDL control Nature reviews. Endocrinology 2018;15 (1):52-62 [PubMed]
  • Farnier Michel, Hovingh G. Kees, Langslet Gisle, Dufour Robert, Baccara-Dinet Marie T., Din-Bell Chantal, Manvelian Garen, Guyton John R. Long-term safety and efficacy of alirocumab in patients with heterozygous familial hypercholesterolemia: An open-label extension of the ODYSSEY program Atherosclerosis 2018;278:307-314 [PubMed]
  • Oldoni Federico, van Capelleveen Julian C., Dalila Nawar, Wolters Justina C., Heeren Joerg, Sinke Richard J., Hui David Y., Dallinga-Thie Geesje M., Frikke-Schmidt Ruth, Hovingh Kees G., van de Sluis Bart, Tybjærg-Hansen Anne, Kuivenhoven Jan Albert Naturally occurring variants in LRP1 (Low-Density lipoprotein receptor-related protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans Arteriosclerosis, thrombosis, and vascular biology 2018;38 (7):1440-1453 [PubMed]
  • Vallejo-Vaz Antonio J., Marco Martina De, Stevens Christophe A. T., Akram Asif, Freiberger Tomas, Hovingh G. Kees, Kastelein John J. P., Mata Pedro, Raal Frederick J., Santos Raul D., Soran Handrean, Watts Gerald F., Abifadel Marianne, Aguilar-Salinas Carlos A., Al-Khnifsawi Mutaz, Alkindi Fahad A., Alnouri Fahad, Alonso Rodrigo, Al-Rasadi Khalid, Al-Sarraf Ahmad, Ashavaid Tester F., Binder Christoph J., Bogsrud Martin P., Bourbon Mafalda, Bruckert Eric, Chlebus Krzysztof, Corral Pablo, Descamps Olivier, Durst Ronen, Ezhov Marat, Fras Zlatko, Genest Jacques, Groselj Urh, Harada-Shiba Mariko, Kayikcioglu Meral, Lalic Katarina, Lam Carolyn S. P., Latkovskis Gustavs, Laufs Ulrich, Liberopoulos Evangelos, Lin Jie, Maher Vincent, Majano Nelson, Marais A. David, März Winfried, Mirrakhimov Erkin, Miserez André R., Mitchenko Olena, Nawawi Hapizah M., Nordestgaard B. rge G., Paragh György, Petrulioniene Zaneta, Pojskic Belma, Postadzhiyan Arman, Reda Ashraf, Reiner Željko, Sadoh Wilson E., Sahebkar Amirhossein, Shehab Abdullah, Shek Aleksander B., Stoll Mario, Su Ta-Chen, Subramaniam Tavintharan, Susekov Andrey V., Symeonides Phivos, Tilney Myra, Tomlinson Brian, Truong Thanh-Huong, Tselepis Alexandros D., Tybjærg-Hansen Anne, Vázquez-Cárdenas Alejandra, Viigimaa Margus, Vohnout Branislav, Widén Elisabeth, Yamashita Shizuya, Banach Maciej, Gaita Dan, Jiang Lixin, Nilsson Lennart, Santos Lourdes E., Schunkert Heribert, Tokgözoğlu Lale, Car Josip, Catapano Alberico L., Ray Kausik K., Akram Asif, Car Josip, Marco Martina De, Ray Kausik K., Stevens Christophe A. T., Vallejo-Vaz Antonio J., Corral Pablo, Schreier Laura, Watts Gerald F., Pang Jing, Binder Christoph J., Dieplinger Hans, Hanauer-Mader Gabriele, Descamps Olivier, Desutter Johan, Langlois Michel, Mertens Ann, Rietzschel Ernst, Wallemacq Caroline, Pojskic Belma, Isakovic Dzenana, Dzankovic Amra M., Obralija Jasna, Pojskic Lamija, Sisic Ibrahim, Stimjanin Ena, Torlak Vildana A., Santos Raul D., Jannes Cinthia E., Krieger Jose E., Pereira Alexandre C., Postadzhiyan Arman, Genest Jacques, Ruel Isabelle, Alonso Rodrigo, Asenjo Sylvia, Cuevas Ada, Lin Jie, Jiang Lixin, Reiner Željko, Pećin Ivan, Symeonides Phivos, Miltiadous George, Panayiotou Andrie G., Freiberger Tomas, Vrablik Michal, Nordestgaard B. rge G., Tybjærg-Hansen Anne, Benn Marianne, Reda Ashraf, Viigimaa Margus, Heinsar Silver, Widén Elisabeth, Bruckert Eric, Béliard S., Laufs Ulrich, März Winfried, Schunkert Heribert, Gouni-Berthold Ioanna, Hengstenberg Wibke, Julius Ulrich, Kassner Ursula, Klose Gerald, König Christel, König Wolfgang, Otte Britta, Parhofer Klaus, Schatz Ulrike, Schmidt Nina, Steinhagen-Thiessen Elisabeth, Vogt Anja, Liberopoulos Evangelos, Tselepis Alexandros D., Antza Christina, Athyros Vasilios, Bilianou Eleni, Boufidou Amalia, Chrousos George, Elisaf Moses, Garoufi Anastasia, Katsiki Niki, Kolovou Genovefa, Kotsis Vasilios, Rallidis Loukianos, Rizos Christos, Skalidis Emmanouel, Skoumas Ioannis, Tziomalos Kostantinos, Tomlinson Brian, Paragh György, Ashavaid Tester F., Shawney J. P. S., Sahebkar Amirhossein, Abbaszadegan Mohammad R., Aminzadeh Majid, Hosseini Sousan, Mobini Moein, Vakili Rahim, Zaeri Hossein, Al-Khnifsawi Mutaz, Maher Vincent, Agar Ruth, Boran Gerard, Colwell Nial, Crowley Vivion, Durkin Maeve, Griffin Damian, Kelly Michael, Rakovac-Tisdall Ana, Durst Ronen, Bitzur Rafael, Cohen Hofit, Eliav Osnat, Ellis Avishay, Gavish Dov, Harats Dror, Henkin Yaacov, Knobler Hila, Leavit Leah, Leitersdorf Eran, Rubinstein Ardon, Schurr Daniel, Shpitzen Shoshi, Szalat Auryan, Catapano Alberico L., Arca Marcello, Averna Maurizio, Bertolini Stefano, Calandra Sebastiano, Tarugi Patrizia, Harada-Shiba Mariko, Yamashita Shizuya, Al-Sarraf Ahmad, Mirrakhimov Erkin, Latkovskis Gustavs, Erglis Andrejs, Gilis Dainus, Nesterovics Georgijs, Saripo Vita, Upena-Roze Arta, Abifadel Marianne, Elbitar Sandy, Jambart S. lim, Khoury Petra El, Petrulioniene Zaneta, Gargalskaite Urte, Kutkiene Sandra, Nawawi Hapizah M., Al-Khateeb Alyaa, An Chua Y., Ismail Zaliha, Kasim Sazzli, Ibrahim Khairul S., Radzi Ahmad B. M., Kasim Noor A., Nor Noor S. M., Ramli Anis S., Razak Suraya A., Muid Suhaila, Rosman Azhari, Sanusi Abd R., Razman Aimi Z., Nazli Sukma A., Kek Teh L., Tilney Myra, Azzopardi Conrad, Aguilar Salinas Carlos A., Vázquez-Cárdenas N. Alejandra, Galán Gabriela, Magaña-Torres M. T., Martagon Alexandro, Mehta Roopa, Hovingh G. Kees, Kastelein John J. P., Wittekoek M. E., Sadoh Wilson E., Isara Alphonsus R., Obaseki Darlington E., Ohenhen Oluwatoyin A., Bogsrud Martin P., Holven Kirsten B., Al-Rasadi Khalid, Santos Lourdes E., Banach Maciej, Chlebus Krzysztof, Gruchała Marcin, Baranowska Marlena, Borowiec-Wolny Justyna, Gilis-Malinowska Natasza, Michalska-Grzonkowska Aleksandra, Pajkowski Marcin, Parczewska Aleksandra, Romanowska-Kocejko Marzena, Stróżyk Aneta, Żarczyńska-Buchowiecka Marta, Kleinschmidt Mariola, Bourbon Mafalda, Alves Ana C., Medeiros Ana M., Alkindi Fahad A., Gaita Dan, Ezhov Marat, Susekov Andrey V., Ershova Alexandra, Korneva Victoria, Kuznetsova Tatiana, Malyshev Pavel, Meshkov Alexey, Rozhkova Tatiana, Alnouri Fahad, Lalic Katarina, Rajkovic Natasa, Popovic Ljiljana, Lukac Sandra S., Stosic Ljubica, Rasulic Iva, Lalic Nebojsa M., Subramaniam Tavintharan, Lam Carolyn S. P., Chua Terrance S. J., Ting Sharon P. L., Vohnout Branislav, Raslova Katarina, Fras Zlatko, Groselj Urh, Battelino Tadej, Cevc Matija, Jug Borut, Kovac Jernej, Podkrajsek Katarina T., Sustar Ursa, Trontelj Katja J., Marais David, Raal Frederick J., Mata Pedro, Isla Leopoldo Perez de, Nilsson Lennart, Miserez André R., Martin François J., Su Ta-Chen, Charng Ming-Ji, Chen Pei-Lung, Kayikçioglu Meral, Tokgözoğlu Lale, Mitchenko Olena, Shehab Abdullah, Soran Handrean, Stoll Mario, Dell’oca Nicolás, Fernández Graciela, Ressia Andrés, Reyes Ximena, Zelarayan Mario, Shek Aleksander B., Alieva Rano B., Hoshimov Shavkat U., Kurbanov Ravshanbek D., Nizamov Ulugbek I., Majano Nelson, Lima-Martínez Marcos M., Truong Thanh-Huong, Nguyen Mai-Ngoc Thi, Do Doan-Loi, Kim Ngoc-Thanh, le Hong-An, le Thanh-Tung Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) Atherosclerosis 2018;277:234-255 [PubMed]
  • Stoekenbroek Robert M., Hartgers Merel L., Rutte Roger, de Wijer Douwe D., Stroes Erik S. G., Hovingh G. Kees PCSK9 inhibitors in clinical practice: Delivering on the promise? Atherosclerosis 2018;270 (March):205-210 [PubMed]
  • Turcot Valérie, Lu Yingchang, Highland Heather M., Schurmann Claudia, Justice Anne E., Fine Rebecca S., Bradfield Jonathan P., Esko Tõnu, Giri Ayush, Graff Mariaelisa, Guo Xiuqing, Hendricks Audrey E., Karaderi Tugce, Lempradl Adelheid, Locke Adam E., Mahajan Anubha, Marouli Eirini, Sivapalaratnam Suthesh, Young Kristin L., Alfred Tamuno, Feitosa Mary F., Masca Nicholas G. D., Manning Alisa K., Medina-Gomez Carolina, Mudgal Poorva, Ng Maggie C. Y., Reiner Alex P., Vedantam Sailaja, Willems Sara M., Winkler Thomas W., Abecasis Gonçalo, Aben Katja K., Alam Dewan S., Alharthi Sameer E., Allison Matthew, Amouyel Philippe, Asselbergs Folkert W., Auer Paul L., Balkau Beverley, Bang Lia E., Barroso Inês, Bastarache Lisa, Benn Marianne, Bergmann Sven, Bielak Lawrence F., Blüher Matthias, Boehnke Michael, Boeing Heiner, Boerwinkle Eric, Böger Carsten A., Bork-Jensen Jette, Bots Michiel L., Bottinger Erwin P., Bowden Donald W., Brandslund Ivan, Breen Gerome, Brilliant Murray H., Broer Linda, Brumat Marco, Burt Amber A., Butterworth Adam S., Campbell Peter T., Cappellani Stefania, Carey David J., Catamo Eulalia, Caulfield Mark J., Chambers John C., Chasman Daniel I., Chen Yii-der I., Chowdhury Rajiv, Christensen Cramer, Chu Audrey Y., Cocca Massimiliano, Collins Francis S., Cook James P., Corley Janie, Corominas Galbany Jordi, Cox Amanda J., Crosslin David S., Cuellar-Partida Gabriel, D'Eustacchio Angela, Danesh John, Davies Gail, Bakker Paul I. W., Groot Mark C. H., Mutsert Renée, Deary Ian J., Dedoussis George, Demerath Ellen W., Heijer Martin, Hollander Anneke I., Ruijter Hester M., Dennis Joe G., Denny Josh C., Angelantonio Emanuele, Drenos Fotios, Du Mengmeng, Dubé Marie-Pierre, Dunning Alison M., Easton Douglas F., Edwards Todd L., Ellinghaus David, Ellinor Patrick T., Elliott Paul, Evangelou Evangelos, Farmaki Aliki-Eleni, Farooqi I. Sadaf, Faul Jessica D., Fauser Sascha, Feng Shuang, Ferrannini Ele, Ferrieres Jean, Florez Jose C., Ford Ian, Fornage Myriam, Franco Oscar H., Franke Andre, Franks Paul W., Friedrich Nele, Frikke-Schmidt Ruth, Galesloot Tessel E., Gan Wei, Gandin Ilaria, Gasparini Paolo, Gibson Jane, Giedraitis Vilmantas, Gjesing Anette P., Gordon-Larsen Penny, Gorski Mathias, Grabe Hans-Jörgen, Grant Struan F. A., Grarup Niels, Griffiths Helen L., Grove Megan L., Gudnason Vilmundur, Gustafsson Stefan, Haessler Jeff, Hakonarson Hakon, Hammerschlag Anke R., Hansen Torben, Harris Kathleen Mullan, Harris Tamara B., Hattersley Andrew T., Have Christian T., Hayward Caroline, He Liang, Heard-Costa Nancy L., Heath Andrew C., Heid Iris M., Helgeland Øyvind, Hernesniemi Jussi, Hewitt Alex W., Holmen Oddgeir L., Hovingh G. Kees, Howson Joanna M. M., Hu Yao, Huang Paul L., Huffman Jennifer E., Ikram M. Arfan, Ingelsson Erik, Jackson Anne U., Jansson Jan-Håkan, Jarvik Gail P., Jensen Gorm B., Jia Yucheng, Johansson Stefan, Jørgensen Marit E., Jørgensen Torben, Jukema J. Wouter, Kahali Bratati, Kahn René S., Kähönen Mika, Kamstrup Pia R., Kanoni Stavroula, Kaprio Jaakko, Karaleftheri Maria, Kardia Sharon L. R., Karpe Fredrik, Kathiresan Sekar, Kee Frank, Kiemeney Lambertus A., Kim Eric, Kitajima Hidetoshi, Komulainen Pirjo, Kooner Jaspal S., Kooperberg Charles, Korhonen Tellervo, Kovacs Peter, Kuivaniemi Helena, Kutalik Zoltán, Kuulasmaa Kari, Kuusisto Johanna, Laakso Markku, Lakka Timo A., Lamparter David, Lange Ethan M., Lange Leslie A., Langenberg Claudia, Larson Eric B., Lee Nanette R., Lehtimäki Terho, Lewis Cora E., Li Huaixing, Li Jin, Li-Gao Ruifang, Lin Honghuang, Lin Keng-Hung, Lin Li-An, Lin Xu, Lind Lars, Lindström Jaana, Linneberg Allan, Liu Ching-Ti, Liu Dajiang J., Liu Yongmei, Lo Ken S., Lophatananon Artitaya, Lotery Andrew J., Loukola Anu, Luan Jian'an, Lubitz Steven A., Lyytikäinen Leo-Pekka, Männistö Satu, Marenne Gaëlle, Mazul Angela L., McCarthy Mark I., McKean-Cowdin Roberta, Medland Sarah E., Meidtner Karina, Milani Lili, Mistry Vanisha, Mitchell Paul, Mohlke Karen L., Moilanen Leena, Moitry Marie, Montgomery Grant W., Mook-Kanamori Dennis O., Moore Carmel, Mori Trevor A., Morris Andrew D., Morris Andrew P., Müller-Nurasyid Martina, Munroe Patricia B., Nalls Mike A., Narisu Narisu, Nelson Christopher P., Neville Matt, Nielsen Sune F., Nikus Kjell, Njølstad Pål R., Nordestgaard Børge G., Nyholt Dale R., O'Connel Jeffrey R., O'Donoghue Michelle L., Olde Loohuis Loes M., Ophoff Roel A., Owen Katharine R., Packard Chris J., Padmanabhan Sandosh, Palmer Colin N. A., Palmer Nicholette D., Pasterkamp Gerard, Patel Aniruddh P., Pattie Alison, Pedersen Oluf, Peissig Peggy L., Peloso Gina M., Pennell Craig E., Perola Markus, Perry James A., Perry John R. B., Pers Tune H., Person Thomas N., Peters Annette, Petersen Eva R. B., Peyser Patricia A., Pirie Ailith, Polasek Ozren, Polderman Tinca J., Puolijoki Hannu, Raitakari Olli T., Rasheed Asif, Rauramaa Rainer, Reilly Dermot F., Renström Frida, Rheinberger Myriam, Ridker Paul M., Rioux John D., Rivas Manuel A., Roberts David J., Robertson Neil R., Robino Antonietta, Rolandsson Olov, Rudan Igor, Ruth Katherine S., Saleheen Danish, Salomaa Veikko, Samani Nilesh J., Sapkota Yadav, Sattar Naveed, Schoen Robert E., Schreiner Pamela J., Schulze Matthias B., Scott Robert A., Segura-Lepe Marcelo P., Shah Svati H., Sheu Wayne H.-H., Sim Xueling, Slater Andrew J., Small Kerrin S., Smith Albert V., Southam Lorraine, Spector Timothy D., Speliotes Elizabeth K., Starr John M., Stefansson Kari, Steinthorsdottir Valgerdur, Stirrups Kathleen E., Strauch Konstantin, Stringham Heather M., Stumvoll Michael, Sun Liang, Surendran Praveen, Swift Amy J., Tada Hayato, Tansey Katherine E., Tardif Jean-Claude, Taylor Kent D., Teumer Alexander, Thompson Deborah J., Thorleifsson Gudmar, Thorsteinsdottir Unnur, Thuesen Betina H., Tönjes Anke, Tromp Gerard, Trompet Stella, Tsafantakis Emmanouil, Tuomilehto Jaakko, Tybjaerg-Hansen Anne, Tyrer Jonathan P., Uher Rudolf, Uitterlinden André G., Uusitupa Matti, Laan Sander W., Duijn Cornelia M., Leeuwen Nienke, van Setten Jessica, Vanhala Mauno, Varbo Anette, Varga Tibor V., Varma Rohit, Velez Edwards Digna R., Vermeulen Sita H., Veronesi Giovanni, Vestergaard Henrik, Vitart Veronique, Vogt Thomas F., Völker Uwe, Vuckovic Dragana, Wagenknecht Lynne E., Walker Mark, Wallentin Lars, Wang Feijie, Wang Carol A., Wang Shuai, Wang Yiqin, Ware Erin B., Wareham Nicholas J., Warren Helen R., Waterworth Dawn M., Wessel Jennifer, White Harvey D., Willer Cristen J., Wilson James G., Witte Daniel R., Wood Andrew R., Wu Ying, Yaghootkar Hanieh, Yao Jie, Yao Pang, Yerges-Armstrong Laura M., Young Robin, Zeggini Eleftheria, Zhan Xiaowei, Zhang Weihua, Zhao Jing Hua, Zhao Wei, Zhou Wei, Zondervan Krina T., Rotter Jerome I., Pospisilik John A., Rivadeneira Fernando, Borecki Ingrid B., Deloukas Panos, Frayling Timothy M., Lettre Guillaume, North Kari E., Lindgren Cecilia M., Hirschhorn Joel N., Loos Ruth J. F. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Nature genetics 2018;50 (1):26-+ [PubMed]
  • van Capelleveen Julian C., Lee Sang-Rok, Verbeek Rutger, Kastelein John J. P., Wareham Nicholas J., Stroes Erik S. G., Hovingh G. Kees, Khaw Kay-Tee, Boekholdt S. Matthijs, Witztum Joseph L., Tsimikas Sotirios Relationship of lipoprotein-associated apolipoprotein C-III with lipid variables and coronary artery disease risk: The EPIC-Norfolk prospective population study Journal of clinical lipidology 2018;12 (6):1493-1501.e11 [PubMed]
  • Vallejo-Vaz Antonio J., Fayyad Rana, Boekholdt S. Matthijs, Hovingh G. Kees, Kastelein John J., Melamed Shari, Barter Philip, Waters David D., Ray Kausik K. Triglyceride-Rich Lipoprotein Cholesterol and Risk of Cardiovascular Events Among Patients Receiving Statin Therapy in the TNT Trial Circulation 2018;138 (8):770-781 [PubMed]

2017

  • Trigueros-Motos Laia, van Capelleveen Julian C., Torta Federico, Castaño David, Zhang Lin-Hua, Chai Ee Chu, Kang Martin, Dimova Lidiya G., Schimmel Alinda W. M., Tietjen Ian, Radomski Chris, Tan Liang Juin, Thiam Chung Hwee, Narayanaswamy Pradeep, Wu Daniel Heqing, Dorninger Fabian, Yakala Gopala Krishna, Barhdadi Amina, Angeli Veronique, Dubé Marie-Pierre, Berger Johannes, Dallinga-Thie Geesje M., Tietge Uwe J. F., Wenk Markus R., Hayden Michael R., Hovingh G. Kees, Singaraja Roshni R. ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels Arteriosclerosis, thrombosis, and vascular biology 2017;37 (11):2147-+ [PubMed]
  • van Capelleveen Julian C., Bernelot Moens Sophie J., Yang Xiaohong, Kastelein John J. P., Wareham Nicholas J., Zwinderman Aeilko H., Stroes Erik S. G., Witztum Joseph L., Hovingh G. Kees, Khaw Kay-Tee, Boekholdt S. Matthijs, Tsimikas Sotirios Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study Arteriosclerosis, thrombosis, and vascular biology 2017;37 (6):1206-1212 [PubMed]
  • van Capelleveen Julian C., Bochem Andrea E., Boekholdt S. Matthijs, Mora Samia, Hoogeveen Ron C., Ballantyne Christie M., Ridker Paul M., Sun Wensheng, Barter Philip J., Tall Alan R., Zwinderman Aeilko H., Kastelein John J. P., Wareham Nick J., Khaw Kay-Tee, Hovingh G. Kees Association of High-Density Lipoprotein-Cholesterol Versus Apolipoprotein A-I With Risk of Coronary Heart Disease: The European Prospective Investigation Into Cancer-Norfolk Prospective Population Study, the Atherosclerosis Risk in Communities Study, and the Women's Health Study Journal of the American Heart Association 2017;6 (8):e006636 [PubMed]
  • Stoekenbroek Robert M., Kastelein John J. P., Hovingh G. Kees Can we afford not to screen for FH? European heart journal 2017;38 (23):1840-1842 [PubMed]
  • Verbeek Rutger, Boyer Marjorie, Boekholdt S. Matthijs, Hovingh G. Kees, Kastelein John J. P., Wareham Nicholas, Khaw Kay-Tee, Arsenault Benoit J. Carriers of the PCSK9 R46L Variant Are Characterized by an Antiatherogenic Lipoprotein Profile Assessed by Nuclear Magnetic Resonance Spectroscopy-Brief Report Arteriosclerosis, thrombosis, and vascular biology 2017;37 (1):43-48 [PubMed]
  • Verbeek Rutger, Hovingh G. Kees Diabetes: Anti-PCSK9 antibodies - beneficial or inducers of diabetes? Nature reviews. Endocrinology 2017;13 (12):694-695 [PubMed]
  • Holzinger Emily R., Verma Shefali S., Moore Carrie B., Hall Molly, de Rishika, Gilbert-Diamond Diane, Lanktree Matthew B., Pankratz Nathan, Amuzu Antoinette, Burt Amber, Dale Caroline, Dudek Scott, Furlong Clement E., Gaunt Tom R., Kim Daniel Seung, Riess Helene, Sivapalaratnam Suthesh, Tragante Vinicius, van Iperen Erik P. A., Brautbar Ariel, Carrell David S., Crosslin David R., Jarvik Gail P., Kuivaniemi Helena, Kullo Iftikhar J., Larson Eric B., Rasmussen-Torvik Laura J., Tromp Gerard, Baumert Jens, Cruickshanks Karen J., Farrall Martin, Hingorani Aroon D., Hovingh G. K., Kleber Marcus E., Klein Barbara E., Klein Ronald, Koenig Wolfgang, Lange Leslie A., Mӓrz Winfried, North Kari E., Charlotte Onland-Moret N., Reiner Alex P., Talmud Philippa J., van der Schouw Yvonne T., Wilson James G., Kivimaki Mika, Kumari Meena, Moore Jason H., Drenos Fotios, Asselbergs Folkert W., Keating Brendan J., Ritchie Marylyn D. Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals BioData mining 2017;10:25 [PubMed]
  • Sjouke Barbara, Elbers Laura P. B., van Zaane Bregje, Kastelein John J. P., Hovingh G. Kees, Gerdes Victor E. A. Effects of Supra-Physiological Levothyroxine Dosages on Liver Parameters, Lipids and Lipoproteins in Healthy Volunteers: A Randomized Controlled Crossover Study Scientific reports 2017;7 (1):14174 [PubMed]
  • Kastelein John J. P., Hovingh G. Kees, Langslet Gisle, Baccara-Dinet Marie T., Gipe Daniel A., Chaudhari Umesh, Zhao Jian, Minini Pascal, Farnier Michel Efficacy and safety of the proprotein convertase subtilisin/kexin type 9 monoclonal antibody alirocumab vs placebo in patients with heterozygous familial hypercholesterolemia Journal of clinical lipidology 2017;11 (1):195-203.e4 [PubMed]
  • Landmesser Ulf, Chapman M. John, Farnier Michel, Gencer Baris, Gielen Stephan, Hovingh G. Kees, Lüscher Thomas F., Sinning David, Tokgözoglu Lale, Wiklund Olov, Zamorano Jose Luis, Pinto Fausto J., Catapano Alberico L. European Society of Cardiology/European Atherosclerosis Society Task Force consensus statement on proprotein convertase subtilisin/kexin type 9 inhibitors: practical guidance for use in patients at very high cardiovascular risk European heart journal 2017;38 (29):2245-2255 [PubMed]
  • Hinney A., Kesselmeier M., Jall S., Volckmar A.-L., Föcker M., Antel J., Heid I. M., Winkler T. W., Grant S. F. A., Guo Y., Bergen A. W., Kaye W., Berrettini W., Hakonarson H., Herpertz-Dahlmann B., de Zwaan M., Herzog W., Ehrlich S., Zipfel S., Egberts K. M., Adan R., Brandys M., van Elburg A., Boraska Perica V., Franklin C. S., Tschöp M. H., Zeggini E., Bulik C. M., Collier D., Scherag A., Müller T. D., Hebebrand J., Perica Vesna Boraska, Franklin Christopher S., Floyd James A. B., Thornton Laura M., Huckins Laura M., Southam Lorraine, Rayner N. William, Tachmazidou Ioanna, Klump Kelly L., Treasure Janet, Lewis Cathryn M., Schmidt Ulrike, Tozzi Federica, Iezebrink Kirsty, Hebebrand Johannes, Gorwood Philip, Trip M. D., Hovingh K. G. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index Molecular psychiatry 2017;22 (2):192-201 [PubMed]
  • van Iperen E. P. A., Hovingh G. K., Asselbergs F. W., Zwinderman A. H. Extending the use of GWAS data by combining data from different genetic platforms PLoS ONE 2017;12 (2):e0172082 [PubMed]
  • Sjouke Barbara Extreme phenotypes in hypercholesterolemia : From genotype to therapy 2017. 367p. ISBN 9789402804867. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kastelein J. J. P.; Co-supervisor: Hovingh G. K.)
  • Hu Xuchen, Dallinga-Thie Geesje M., Hovingh G. Kees, Chang Sandy Y., Sandoval Norma P., Dang Tiffany Ly P., Fukamachi Isamu, Miyashita Kazuya, Nakajima Katsuyuki, Murakami Masami, Fong Loren G., Ploug Michael, Young Stephen G., Beigneux Anne P. GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia Journal of clinical lipidology 2017;11 (4):964-971 [PubMed]
  • Stoekenbroek Robert M., Kees Hovingh G., Kastelein John J. P. Homozygous familial hypercholesterolaemia: light at the end of the tunnel European heart journal 2017;39 (14):1169-1171 [PubMed]
  • Perrot Nicolas, Verbeek Rutger, Sandhu Manjinder, Boekholdt S. Matthijs, Hovingh G. Kees, Wareham Nicholas J., Khaw Kay-Tee, Arsenault Benoit J. Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: The EPIC-Norfolk prospective population study Atherosclerosis 2017;256:47-52 [PubMed]
  • Rosenson Robert S., Gandra Shravanthi R., McKendrick Jan, Dent Ricardo, Wieffer Heather, Cheng Lung-I., Catapano Alberico L., Oh Paul, Kees Hovingh G., Stroes Erik S. Identification and Management of Statin-Associated Symptoms in Clinical Practice: Extension of a Clinician Survey to 12 Further Countries Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2017;31 (2):187-195 [PubMed]
  • van Capelleveen Julian C. Identification and targeting of genes in atherosclerosis 2017. 342p. ISBN 9789462997585. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Stroes E. S. G., Hovingh G. K.; Co-supervisor: Dallinga-Thie G. M.)
  • Wheeler Eleanor, Leong Aaron, Liu Ching-Ti, Hivert Marie-France, Strawbridge Rona J., Podmore Clara, Li Man, Yao Jie, Sim Xueling, Hong Jaeyoung, Chu Audrey Y., Zhang Weihua, Wang Xu, Chen Peng, Maruthur Nisa M., Porneala Bianca C., Sharp Stephen J., Jia Yucheng, Kabagambe Edmond K., Chang Li-Ching, Chen Wei-Min, Elks Cathy E., Evans Daniel S., Fan Qiao, Giulianini Franco, Go Min Jin, Hottenga Jouke-Jan, Hu Yao, Jackson Anne U., Kanoni Stavroula, Kim Young Jin, Kleber Marcus E., Ladenvall Claes, Lecoeur Cecile, Lim Sing-Hui, Lu Yingchang, Mahajan Anubha, Marzi Carola, Nalls Mike A., Navarro Pau, Nolte Ilja M., Rose Lynda M., Rybin Denis V., Sanna Serena, Shi Yuan, Stram Daniel O., Takeuchi Fumihiko, Tan Shu Pei, van der Most Peter J., van Vliet-Ostaptchouk Jana V., Wong Andrew, Yengo Loic, Zhao Wanting, Goel Anuj, Martinez Larrad Maria Teresa, Radke Dorte, Salo Perttu, Tanaka Toshiko, van Iperen Erik P. A., Abecasis Goncalo, Afaq Saima, Alizadeh Behrooz Z., Bertoni Alain G., Bonnefond Amelie, Bottcher Yvonne, Bottinger Erwin P., Campbell Harry, Carlson Olga D., Chen Chien-Hsiun, Cho Yoon Shin, Garvey W. Timothy, Gieger Christian, Goodarzi Mark O., Grallert Harald, Hamsten Anders, Hartman Catharina A., Herder Christian, Hsiung Chao Agnes, Huang Jie, Igase Michiya, Isono Masato, Katsuya Tomohiro, Khor Chiea-Chuen, Kiess Wieland, Kohara Katsuhiko, Kovacs Peter, Lee Juyoung, Lee Wen-Jane, Lehne Benjamin, Li Huaixing, Liu Jianjun, Lobbens Stephane, Luan Jian'an, Lyssenko Valeriya, Meitinger Thomas, Miki Tetsuro, Miljkovic Iva, Moon Sanghoon, Mulas Antonella, Muller Gabriele, Muller-Nurasyid Martina, Nagaraja Ramaiah, Nauck Matthias, Pankow James S., Polasek Ozren, Prokopenko Inga, Ramos Paula S., Rasmussen-Torvik Laura, Rathmann Wolfgang, Rich Stephen S., Robertson Neil R., Roden Michael, Roussel Ronan, Rudan Igor, Scott Robert A., Scott William R., Sennblad Bengt, Siscovick David S., Strauch Konstantin, Sun Liang, Swertz Morris, Tajuddin Salman M., Taylor Kent D., teo Yik-Ying, Tham Yih Chung, Tonjes Anke, Wareham Nicholas J., Willemsen Gonneke, Wilsgaard Tom, Hingorani Aroon D., Egan Josephine, Ferrucci Luigi, Hovingh G. Kees, Jula Antti, Kivimaki Mika, Kumari Meena, Njolstad Inger, Palmer Colin N. A., Serrano Rios Manuel, Stumvoll Michael, Watkins Hugh, Aung Tin, Bluher Matthias, Boehnke Michael, Boomsma Dorret I., Bornstein Stefan R., Chambers John C., Chasman Daniel I., Chen Yii-Der Ida, Chen Yduan-Tsong, Cheng Ching-Yu, Cucca Francesco, de Geus Eco J. C., Deloukas Panos, Evans Michele K., Fornage Myriam, Friedlander Yechiel, Froguel Philippe, Groop Leif, Gross Myron D., Harris Tamara B., Hayward Caroline, Heng Chew-Kiat, Ingelsson Erik, Kato Norihiro, Kim Bong-Jo, Koh Woon-Puay, Kooner Jaspal S., Korner Antje, Kuh Diana, Kuusisto Johanna, Laakso Markku, Lin Xu, Liu Yongmei, Loos Ruth J. F., Magnusson Patrik K. E., Marz Winfried, McCarthy Mark I., Oldehinkel Albertine J., Ong Ken K., Pedersen Nancy L., Pereira Mark A., Peters Annette, Ridker Paul M., Sabanayagam Charumathi, Sale Michele, Saleheen Danish, Saltevo Juha, Schwarz Peter Eh, Sheu Wayne H. H., Snieder Harold, Spector Timothy D., Tabara Yasuharu, Tuomilehto Jaakko, van Dam Rob M., Wilson James G., Wilson James F., Wolffenbuttel Bruce H. R., Wong Tien Yin, Wu Jer-Yuarn, Yuan Jian-Min, Zonderman Alan B., Soranzo Nicole, Guo Xiuqing, Roberts David J., Florez Jose C., Sladek Robert, Dupuis Josee, Morris Andrew P., Tai E.-Shyong, Selvin Elizabeth, Rotter Jerome I., Langenberg Claudia, Barroso Ines, Meigs James B. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis PLoS medicine 2017;14 (9):e1002383 [PubMed]
  • Verbeek Rutger, Sandhu Manjinder S., Hovingh G. Kees, Sjouke Barbara, Wareham Nicholas J., Zwinderman Aeilko H., Kastelein John J. P., Khaw Kay-Tee, Tsimikas Sotirios, Boekholdt S. Matthijs Lipoprotein(a) Improves Cardiovascular Risk Prediction Based on Established Risk Algorithms Journal of the American College of Cardiology 2017;69 (11):1513-1515 [PubMed]
  • Hovingh G. Kees, Raal Frederick J., Dent Ricardo, Stefanutti Claudia, Descamps Olivier, Masana Luis, Lira Armando, Bridges Ian, Coll Blai, Sullivan David Long-term safety, tolerability, and efficacy of evolocumab in patients with heterozygous familial hypercholesterolemia Journal of clinical lipidology 2017;11 (6):1448-1457 [PubMed]
  • Raal Frederick J., Hovingh G. Kees, Blom Dirk, Santos Raul D., Harada-Shiba Mariko, Bruckert Eric, Couture Patrick, Soran Handrean, Watts Gerald F., Kurtz Christopher, Honarpour Narimon, Tang Lihua, Kasichayanula Sree, Wasserman Scott M., Stein Evan A. Long-term treatment with evolocumab added to conventional drug therapy, with or without apheresis, in patients with homozygous familial hypercholesterolaemia: an interim subset analysis of the open-label TAUSSIG study Lancet. Diabetes and endocrinology 2017;5 (4):280-290 [PubMed]
  • Hovingh G. Kees, Goldberg Anne C., Moriarty Patrick M. Managing the challenging homozygous familial hypercholesterolemia patient: Academic insights and practical approaches for a severe dyslipidemia, a National Lipid Association Masters Summit Journal of clinical lipidology 2017;11 (3):602-616 [PubMed]
  • Bruikman Caroline S., Hovingh Gerard K., Kastelein John J. P. Molecular basis of familial hypercholesterolemia Current opinion in cardiology 2017;32 (3):262-266 [PubMed]
  • Bruikman Caroline S., Stoekenbroek Robert M., Hovingh G. Kees, Kastelein John P. New Drugs for Atherosclerosis Canadian journal of cardiology 2017;33 (3):350-357 [PubMed]
  • Dufour Robert, Bergeron Jean, Gaudet Daniel, Weiss Robert, Hovingh G. Kees, Qing Zhizhi, Yang Feng, Andisik Matthew, Torri Albert, Pordy Robert, Gipe Daniel A. Open-label therapy with alirocumab in patients with heterozygous familial hypercholesterolemia: Results from three years of treatment International journal of cardiology 2017;228:754-760 [PubMed]
  • Schmidt Amand F., Swerdlow Daniel I., Holmes Michael V., Patel Riyaz S., Fairhurst-Hunter Zammy, Lyall Donald M., Hartwig Fernando Pires, Horta Bernardo Lessa, Hyppönen Elina, Power Christine, Moldovan Max, van Iperen Erik, Hovingh G. Kees, Demuth Ilja, Norman Kristina, Steinhagen-Thiessen Elisabeth, Demuth Juri, Bertram Lars, Liu Tian, Coassin Stefan, Willeit Johann, Kiechl Stefan, Willeit Karin, Mason Dan, Wright John, Morris Richard, Wanamethee Goya, Whincup Peter, Ben-Shlomo Yoav, McLachlan Stela, Price Jackie F., Kivimaki Mika, Welch Catherine, Sanchez-Galvez Adelaida, Marques-Vidal Pedro, Nicolaides Andrew, Panayiotou Andrie G., Onland-Moret N. Charlotte, van der Schouw Yvonne T., Matullo Giuseppe, Fiorito Giovanni, Guarrera Simonetta, Sacerdote Carlotta, Wareham Nicholas J., Langenberg Claudia, Scott Robert, Luan Jian'an, Bobak Martin, Malyutina Sofia, Pająk Andrzej, Kubinova Ruzena, Tamosiunas Abdonas, Pikhart Hynek, Husemoen Lise Lotte Nystrup, Grarup Niels, Pedersen Oluf, Hansen Torben, Linneberg Allan, Simonsen Kenneth Starup, Cooper Jackie, Humphries Steve E., Brilliant Murray, Kitchner Terrie, Hakonarson Hakon, Carrell David S., McCarty Catherine A., Kirchner H. Lester, Larson Eric B., Crosslin David R., de Andrade Mariza, Roden Dan M., Denny Joshua C., Carty Cara, Hancock Stephen, Attia John, Holliday Elizabeth, O'Donnell Martin, Yusuf Salim, Chong Michael, Pare Guillaume, van der Harst Pim, Said M. Abdullah, Eppinga Ruben N., Verweij Niek, Snieder Harold, Christen Tim, Mook-Kanamori Dennis O., Gustafsson Stefan, Lind Lars, Ingelsson Erik, Pazoki Raha, Franco Oscar, Hofman Albert, Uitterlinden Andre, Dehghan Abbas, Teumer Alexander, Baumeister Sebastian, Dörr Marcus, Lerch Markus M., Völker Uwe, Völzke Henry, Ward Joey, Pell Jill P., Smith Daniel J., Meade Tom, Maitland-van der Zee Anke H., Baranova Ekaterina V., Young Robin, Ford Ian, Campbell Archie, Padmanabhan Sandosh, Bots Michiel L., Grobbee Diederick E., Froguel Philippe, Thuillier Dorothée, Balkau Beverley, Bonnefond Amélie, Cariou Bertrand, Smart Melissa, Bao Yanchun, Kumari Meena, Mahajan Anubha, Ridker Paul M., Chasman Daniel I., Reiner Alex P., Lange Leslie A., Ritchie Marylyn D., Asselbergs Folkert W., Casas Juan-Pablo, Keating Brendan J., Preiss David, Hingorani Aroon D., Sattar Naveed PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study Lancet. Diabetes and endocrinology 2017;5 (2):97-105 [PubMed]
  • Sjouke Barbara, Yahya Reyhana, Tanck Michael W. T., Defesche Joep C., de Graaf Jacqueline, Wiegman Albert, Kastelein John J. P., Mulder Monique T., Hovingh G. Kees, Roeters van Lennep Jeanine E. Plasma lipoprotein(a) levels in patients with homozygous autosomal dominant hypercholesterolemia Journal of clinical lipidology 2017;11 (2):507-514 [PubMed]
  • Pećin Ivan, Hartgers Merel L., Hovingh G. Kees, Dent Ricardo, Reiner Željko Prevention of cardiovascular disease in patients with familial hypercholesterolaemia: The role of PCSK9 inhibitors European journal of preventive cardiology 2017;24 (13):1383-1401 [PubMed]
  • Marouli Eirini, Graff Mariaelisa, Medina-Gomez Carolina, Lo Ken Sin, Wood Andrew R., Kjaer Troels R., Fine Rebecca S., Lu Yingchang, Schurmann Claudia, Highland Heather M., Rüeger Sina, Thorleifsson Gudmar, Justice Anne E., Lamparter David, Stirrups Kathleen E., Turcot Valérie, Young Kristin L., Winkler Thomas W., Esko Tõnu, Karaderi Tugce, Locke Adam E., Masca Nicholas G. D., Ng Maggie C. Y., Mudgal Poorva, Rivas Manuel A., Vedantam Sailaja, Mahajan Anubha, Guo Xiuqing, Abecasis Goncalo, Aben Katja K., Adair Linda S., Alam Dewan S., Albrecht Eva, Allin Kristine H., Allison Matthew, Amouyel Philippe, Appel Emil V., Arveiler Dominique, Asselbergs Folkert W., Auer Paul L., Balkau Beverley, Banas Bernhard, Bang Lia E., Benn Marianne, Bergmann Sven, Bielak Lawrence F., Blüher Matthias, Boeing Heiner, Boerwinkle Eric, Böger Carsten A., Bonnycastle Lori L., Bork-Jensen Jette, Bots Michiel L., Bottinger Erwin P., Bowden Donald W., Brandslund Ivan, Breen Gerome, Brilliant Murray H., Broer Linda, Burt Amber A., Butterworth Adam S., Carey David J., Caulfield Mark J., Chambers John C., Chasman Daniel I., Chen Yii-Der Ida, Chowdhury Rajiv, Christensen Cramer, Chu Audrey Y., Cocca Massimiliano, Collins Francis S., Cook James P., Corley Janie, Galbany Jordi Corominas, Cox Amanda J., Cuellar-Partida Gabriel, Danesh John, Davies Gail, de Bakker Paul I. W., de Borst Gert J., de Denus Simon, de Groot Mark C. H., de Mutsert Renée, Deary Ian J., Dedoussis George, Demerath Ellen W., den Hollander Anneke I., Dennis Joe G., Di Angelantonio Emanuele, Drenos Fotios, Du Mengmeng, Dunning Alison M., Easton Douglas F., Ebeling Tapani, Edwards Todd L., Ellinor Patrick T., Elliott Paul, Evangelou Evangelos, Farmaki Aliki-Eleni, Faul Jessica D., Feitosa Mary F., Feng Shuang, Ferrannini Ele, Ferrario Marco M., Ferrieres Jean, Florez Jose C., Ford Ian, Fornage Myriam, Franks Paul W., Frikke-Schmidt Ruth, Galesloot Tessel E., Gan Wei, Gandin Ilaria, Gasparini Paolo, Giedraitis Vilmantas, Giri Ayush, Girotto Giorgia, Gordon Scott D., Gordon-Larsen Penny, Gorski Mathias, Grarup Niels, Grove Megan L., Gudnason Vilmundur, Gustafsson Stefan, Hansen Torben, Harris Kathleen Mullan, Harris Tamara B., Hattersley Andrew T., Hayward Caroline, He Liang, Heid Iris M., Heikkilä Kauko, Helgeland Øyvind, Hernesniemi Jussi, Hewitt Alex W., Hocking Lynne J., Hollensted Mette, Holmen Oddgeir L., Hovingh G. Kees, Howson Joanna M. M., Hoyng Carel B., Huang Paul L., Hveem Kristian, Ikram M. Arfan, Ingelsson Erik, Jackson Anne U., Jansson Jan-Håkan, Jarvik Gail P., Jensen Gorm B., Jhun Min A., Jia Yucheng, Jiang Xuejuan, Johansson Stefan, Jørgensen Marit E., Jørgensen Torben, Jousilahti Pekka, Jukema J. Wouter, Kahali Bratati, Kahn René S., Kähönen Mika, Kamstrup Pia R., Kanoni Stavroula, Kaprio Jaakko, Karaleftheri Maria, Kardia Sharon L. R., Karpe Fredrik, Kee Frank, Keeman Renske, Kiemeney Lambertus A., Kitajima Hidetoshi, Kluivers Kirsten B., Kocher Thomas, Komulainen Pirjo, Kontto Jukka, Kooner Jaspal S., Kooperberg Charles, Kovacs Peter, Kriebel Jennifer, Kuivaniemi Helena, Küry Sébastien, Kuusisto Johanna, La Bianca Martina, Laakso Markku, Lakka Timo A., Lange Ethan M., Lange Leslie A., Langefeld Carl D., Langenberg Claudia, Larson Eric B., Lee I.-Te, Lehtimäki Terho, Lewis Cora E., Li Huaixing, Li Jin, Li-Gao Ruifang, Lin Honghuang, Lin Li-An, Lin Xu, Lind Lars, Lindström Jaana, Linneberg Allan, Liu Yeheng, Liu Yongmei, Lophatananon Artitaya, Luan Jian'an, Lubitz Steven A., Lyytikäinen Leo-Pekka, Mackey David A., Madden Pamela A. F., Manning Alisa K., Männistö Satu, Marenne Gaëlle, Marten Jonathan, Martin Nicholas G., Mazul Angela L., Meidtner Karina, Metspalu Andres, Mitchell Paul, Mohlke Karen L., Mook-Kanamori Dennis O., Morgan Anna, Morris Andrew D., Morris Andrew P., Müller-Nurasyid Martina, Munroe Patricia B., Nalls Mike A., Nauck Matthias, Nelson Christopher P., Neville Matt, Nielsen Sune F., Nikus Kjell, Njølstad Pål R., Nordestgaard Børge G., Ntalla Ioanna, O'Connel Jeffrey R., Oksa Heikki, Loohuis Loes M. Olde, Ophoff Roel A., Owen Katharine R., Packard Chris J., Padmanabhan Sandosh, Palmer Colin N. A., Pasterkamp Gerard, Patel Aniruddh P., Pattie Alison, Pedersen Oluf, Peissig Peggy L., Peloso Gina M., Pennell Craig E., Perola Markus, Perry James A., Perry John R. B., Person Thomas N., Pirie Ailith, Polasek Ozren, Posthuma Danielle, Raitakari Olli T., Rasheed Asif, Rauramaa Rainer, Reilly Dermot F., Reiner Alex P., Renström Frida, Ridker Paul M., Rioux John D., Robertson Neil, Robino Antonietta, Rolandsson Olov, Rudan Igor, Ruth Katherine S., Saleheen Danish, Salomaa Veikko, Samani Nilesh J., Sandow Kevin, Sapkota Yadav, Sattar Naveed, Schmidt Marjanka K., Schreiner Pamela J., Schulze Matthias B., Scott Robert A., Segura-Lepe Marcelo P., Shah Svati, Sim Xueling, Sivapalaratnam Suthesh, Small Kerrin S., Smith Albert Vernon, Smith Jennifer A., Southam Lorraine, Spector Timothy D., Speliotes Elizabeth K., Starr John M., Steinthorsdottir Valgerdur, Stringham Heather M., Stumvoll Michael, Surendran Praveen, 't Hart Leen M., Tansey Katherine E., Tardif Jean-Claude, Taylor Kent D., Teumer Alexander, Thompson Deborah J., Thorsteinsdottir Unnur, Thuesen Betina H., Tönjes Anke, Tromp Gerard, Trompet Stella, Tsafantakis Emmanouil, Tuomilehto Jaakko, Tybjaerg-Hansen Anne, Tyrer Jonathan P., Uher Rudolf, Uitterlinden André G., Ulivi Sheila, van der Laan Sander W., van der Leij Andries R., van Duijn Cornelia M., van Schoor Natasja M., van Setten Jessica, Varbo Anette, Varga Tibor V., Varma Rohit, Edwards Digna R. Velez, Vermeulen Sita H., Vestergaard Henrik, Vitart Veronique, Vogt Thomas F., Vozzi Diego, Walker Mark, Wang Feijie, Wang Carol A., Wang Shuai, Wang Yiqin, Wareham Nicholas J., Warren Helen R., Wessel Jennifer, Willems Sara M., Wilson James G., Witte Daniel R., Woods Michael O., Wu Ying, Yaghootkar Hanieh, Yao Jie, Yao Pang, Yerges-Armstrong Laura M., Young Robin, Zeggini Eleftheria, Zhan Xiaowei, Zhang Weihua, Zhao Jing Hua, Zhao Wei, Zheng He, Zhou Wei, Rotter Jerome I., Boehnke Michael, Kathiresan Sekar, McCarthy Mark I., Willer Cristen J., Stefansson Kari, Borecki Ingrid B., Liu Dajiang J., North Kari E., Heard-Costa Nancy L., Pers Tune H., Lindgren Cecilia M., Oxvig Claus, Kutalik Zoltán, Rivadeneira Fernando, Loos Ruth J. F., Frayling Timothy M., Hirschhorn Joel N., Deloukas Panos, Lettre Guillaume Rare and low-frequency coding variants alter human adult height Nature 2017;542 (7640):186-190 [PubMed]
  • Besseling Joost, Reitsma Johannes B., Gaudet Daniel, Brisson Diane, Kastelein John J. P., Hovingh G. Kees, Hutten Barbara A. Selection of individuals for genetic testing for familial hypercholesterolaemia: development and external validation of a prediction model for the presence of a mutation causing familial hypercholesterolaemia European heart journal 2017;38 (8):565-573 [PubMed]
  • Webb Thomas R., Erdmann Jeanette, Stirrups Kathleen E., Stitziel Nathan O., Masca Nicholas G. D., Jansen Henning, Kanoni Stavroula, Nelson Christopher P., Ferrario Paola G., König Inke R., Eicher John D., Johnson Andrew D., Hamby Stephen E., Betsholtz Christer, Ruusalepp Arno, Franzén Oscar, Schadt Eric E., Björkegren Johan L. M., Weeke Peter E., Auer Paul L., Schick Ursula M., Lu Yingchang, Zhang He, Dube Marie-Pierre, Goel Anuj, Farrall Martin, Peloso Gina M., Won Hong-Hee, Do Ron, van Iperen Erik, Kruppa Jochen, Mahajan Anubha, Scott Robert A., Willenborg Christina, Braund Peter S., van Capelleveen Julian C., Doney Alex S. F., Donnelly Louise A., Asselta Rosanna, Merlini Pier A., Duga Stefano, Marziliano Nicola, Denny Josh C., Shaffer Christian, El-Mokhtari Nour Eddine, Franke Andre, Heilmann Stefanie, Hengstenberg Christian, Hoffmann Per, Holmen Oddgeir L., Hveem Kristian, Jansson Jan-Håkan, Jöckel Karl-Heinz, Kessler Thorsten, Kriebel Jennifer, Laugwitz Karl L., Marouli Eirini, Martinelli Nicola, McCarthy Mark I., van Zuydam Natalie R., Meisinger Christa, Esko Tõnu, Mihailov Evelin, Escher Stefan A., Alver Maris, Moebus Susanne, Morris Andrew D., Virtamo Jarma, Nikpay Majid, Olivieri Oliviero, Provost Sylvie, AlQarawi Alaa, Robertson Neil R., Akinsansya Karen O., Reilly Dermot F., Vogt Thomas F., Yin Wu, Asselbergs Folkert W., Kooperberg Charles, Jackson Rebecca D., Stahl Eli, Müller-Nurasyid Martina, Strauch Konstantin, Varga Tibor V., Waldenberger Melanie, Zeng Lingyao, Chowdhury Rajiv, Salomaa Veikko, Ford Ian, Jukema J. Wouter, Amouyel Philippe, Kontto Jukka, Nordestgaard Børge G., Ferrières Jean, Saleheen Danish, Sattar Naveed, Surendran Praveen, Wagner Aline, Young Robin, Howson Joanna M. M., Butterworth Adam S., Danesh John, Ardissino Diego, Bottinger Erwin P., Erbel Raimund, Franks Paul W., Girelli Domenico, Hall Alistair S., Hovingh G. Kees, Kastrati Adnan, Lieb Wolfgang, Meitinger Thomas, Kraus William E., Shah Svati H., McPherson Ruth, Orho-Melander Marju, Melander Olle, Metspalu Andres, Palmer Colin N. A., Peters Annette, Rader Daniel J., Reilly Muredach P., Loos Ruth J. F., Reiner Alex P., Roden Dan M., Tardif Jean-Claude, Thompson John R., Wareham Nicholas J., Watkins Hugh, Willer Cristen J., Samani Nilesh J., Schunkert Heribert, Deloukas Panos, Kathiresan Sekar Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease Journal of the American College of Cardiology 2017;69 (7):823-836 [PubMed]
  • Leipold Robert, Raal Frederick, Ishak Jack, Hovingh Kees, Phillips Helen The effect of lomitapide on cardiovascular outcome measures in homozygous familial hypercholesterolemia: A modelling analysis European journal of preventive cardiology 2017;24 (17):1843-1850 [PubMed]
  • Ursoniu Sorin, Mikhailidis Dimitri P., Serban Maria-Corina, Penson Peter, Toth Peter P., Ridker Paul M., Ray Kausik K., Kees Hovingh G., Kastelein John J., Hernandez Adrian V., Manson JoAnn E., Rysz Jacek, Banach Maciej The effect of statins on cardiovascular outcomes by smoking status: A systematic review and meta-analysis of randomized controlled trials Pharmacological research 2017;122:105-117 [PubMed]
  • Hovingh G. Kees, Boekholdt S. Matthijs, Stroes Erik S. Very low LDL-cholesterol concentrations achieved: which target is next? Lancet 2017;390 (10106):1930-1931 [PubMed]

2016

  • Nüesch Eveline, Dale Caroline, Palmer Tom M., White Jon, Keating Brendan J., van Iperen Erik Pa, Goel Anuj, Padmanabhan Sandosh, Asselbergs Folkert W., Verschuren W. M., Wijmenga C., van der Schouw Y. T., Onland-Moret N. C., Lange Leslie A., Hovingh G. K., Sivapalaratnam Suthesh, Morris Richard W., Whincup Peter H., Wannamethe Goya S., Gaunt Tom R., Ebrahim Shah, Steel Laura, Nair Nikhil, Reiner Alexander P., Kooperberg Charles, Wilson James F., Bolton Jennifer L., McLachlan Stela, Price Jacqueline F., Strachan Mark Wj, Robertson Christine M., Kleber Marcus E., Delgado Graciela, März Winfried, Melander Olle, Dominiczak Anna F., Farrall Martin, Watkins Hugh, Leusink Maarten, Maitland-van der Zee Anke H., de Groot Mark Ch, Dudbridge Frank, Hingorani Aroon, Ben-Shlomo Yoav, Lawlor Debbie A., Amuzu A., Caufield M., Cavadino A., Cooper J., Davies T. L., Drenos F., Engmann J., Finan C., Giambartolomei C., Hardy R., Humphries S. E., Hypponen E., Kivimaki M., Kuh D., Kumari M., Ong K., Plagnol V., Power C., Richards M., Shah S., Shah T., Sofat R., Talmud P. J., Wareham N., Warren H., Whittaker J. C., Wong A., Zabaneh D., Davey Smith George, Wells Jonathan C., Leon David A., Holmes Michael V., Casas Juan P. Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis International journal of epidemiology 2016;45 (6):1927-1937 [PubMed]
  • Leusink Maarten, Maitland-van der Zee Anke H., Ding Bo, Drenos Fotios, van Iperen Erik Pa, Warren Helen R., Caulfield Mark J., Cupples L. Adrienne, Cushman Mary, Hingorani Aroon D., Hoogeveen Ron C., Hovingh G. Kees, Kumari Meena, Lange Leslie A., Munroe Patricia B., Nyberg Fredrik, Schreiner Pamela J., Sivapalaratnam Suthesh, de Bakker Paul Iw, de Boer Anthonius, Keating Brendan J., Asselbergs Folkert W., Onland-Moret N. Charlotte A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering Pharmacogenomics 2016;17 (6):583-591 [PubMed]
  • Motazacker Mahdi M., Pirhonen Juho, van Capelleveen Julian C., Weber-Boyvat Marion, Kuivenhoven Jan Albert, Shah Saundarya, Hovingh G. Kees, Metso Jari, Li Shiqian, Ikonen Elina, Jauhiainen Matti, Dallinga-Thie Geesje M., Olkkonen Vesa M. A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity Atherosclerosis 2016;249:140-147 [PubMed]
  • Maiwald Stephanie, Motazacker Mahdi M., van Capelleveen Julian C., Sivapalaratnam Suthesh, van der Wal Allard C., van der Loos Chris, Kastelein John J. P., Ouwehand Willem H., Hovingh G. Kees, Trip Mieke D., van Buul Jaap D., Dallinga-Thie Geesje M. A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosis European journal of human genetics 2016;24 (1):86-91 [PubMed]
  • Sjouke Barbara, Tanck Michael W. T., Fouchier Sigrid W., Defesche Joep C., Hutten Barbara A., Wiegman Albert, Kastelein John J. P., Hovingh G. Kees Children with hypercholesterolemia of unknown cause: Value of genetic risk scores Journal of clinical lipidology 2016;10 (4):851-859 [PubMed]
  • Besseling Joost, Huijgen Roeland, Martin Seth S., Hutten Barbara A., Kastelein John J. P., Hovingh G. Kees Clinical phenotype in relation to the distance-to-index-patient in familial hypercholesterolemia Atherosclerosis 2016;246:1-6 [PubMed]
  • Stitziel Nathan O., Stirrups Kathleen E., Masca Nicholas G. D., Erdmann Jeanette, Ferrario Paola G., König Inke R., Weeke Peter E., Webb Thomas R., Auer Paul L., Schick Ursula M., Lu Yingchang, Zhang He, Dube Marie-Pierre, Goel Anuj, Farrall Martin, Peloso Gina M., Won Hong-Hee, Do Ron, van Iperen Erik, Kanoni Stavroula, Kruppa Jochen, Mahajan Anubha, Scott Robert A., Willenborg Christina, Braund Peter S., van Capelleveen Julian C., Doney Alex S. F., Donnelly Louise A., Asselta Rosanna, Merlini Piera A., Duga Stefano, Marziliano Nicola, Denny Josh C., Shaffer Christian M., El-Mokhtari Nour Eddine, Franke Andre, Gottesman Omri, Heilmann Stefanie, Hengstenberg Christian, Hoffmann Per, Holmen Oddgeir L., Hveem Kristian, Jansson Jan-Håkan, Jöckel Karl-Heinz, Kessler Thorsten, Kriebel Jennifer, Laugwitz Karl L., Marouli Eirini, Martinelli Nicola, Hovingh G. Kees Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease New England journal of medicine 2016;374 (12):1134-1144 [PubMed]
  • Stitziel Nathan O., Stirrups Kathleen E., Masca Nicholas G. D., Erdmann Jeanette, Ferrario Paola G., Koenig Inke R., Weeke Peter E., Webb Thomas R., Auer Paul L., Schick Ursula M., Lu Yingchang, Zhang He, Dube Marie-Pierre, Goel Anuj, Farrall Martin, Peloso Gina M., Won Hong-Hee, Do Ron, van Iperen Erik, Kanoni Stavroula, Kruppa Jochen, Mahajan Anubha, Scott Robert A., Willenborg Christina, Braund Peter S., van Capelleveen Julian C., Doney Alex S. F., Donnelly Louise A., Asselta Rosanna, Merlini Piera A., Duga Stefano, Marziliano Nicola, Denny Josh C., Shaffer Christian M., El-Mokhtari Nour Eddine, Franke Andre, Gottesman Omri, Heilmann Stefanie, Hengstenberg Christian, Hoffmann Per, Holmen Oddgeir L., Hveem Kristian, Jansson Jan-Hakan, Joeckel Karl-Heinz, Kessler Thorsten, Kriebel Jennifer, Laugwitz Karl L., Marouli Eirini, Martinelli Nicola, McCarthy Mark I., van Zuydam Natalie R., Meisinger Christa, Esko Tonu, Mihailov Evelin, Escher Stefan A., Alver Maris, Moebus Susanne, Morris Andrew D., Muller-Nurasyid Martina, Nikpay Majid, Olivieri Oliviero, Perreault Louis-Philippe Lemieux, AlQarawi Alaa, Robertson Neil R., Akinsanya Karen O., Reilly Dermot F., Vogt Thomas F., Yin Wu, Asselbergs Folkert W., Kooperberg Charles, Jackson Rebecca D., Stahl Eli, Strauch Konstantin, Varga Tibor V., Waldenberger Melanie, Zeng Lingyao, Kraja Aldi T., Liu Chunyu, Ehret Georg B., Newton-Cheh Christopher, Chasman Daniel I., Chowdhury Rajiv, Ferrario Marco, Ford Ian, Jukema J. Wouter, Kee Frank, Kuulasmaa Kari, Nordestgaard Borge G., Perola Markus, Saleheen Danish, Sattar Naveed, Surendran Praveen, Tregouet David, Young Robin, Howson Joanna M. M., Butterworth Adam S., Danesh John, Ardissino Diego, Bottinger Erwin P., Erbel Raimund, Franks Paul W., Girelli Domenico, Hall Alistair S., Hovingh G. Kees, Kastrati Adnan, Lieb Wolfgang, Meitinger Thomas, Kraus William E., Shah Svati H., McPherson Ruth, Orho-Melander Marju, Melander Olle, Metspalu Andres, Palmer Colin N. A., Peters Annette, Rader Daniel J., Reilly Muredach P., Loos Ruth J. F., Reiner Alex P., Roden Dan M., Tardif Jean-Claude, Thompson John R., Wareham Nicholas J., Watkins Hugh, Willer Cristen J., Kathiresan Sekar, Deloukas Panos, Samani Nilesh J., Schunkert Heribert Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease (vol 374, pg 1134, 2016) New England journal of medicine 2016;374 (19):1898
  • Santos Raul D., Gidding Samuel S., Hegele Robert A., Cuchel Marina A., Barter Philip J., Watts Gerald F., Baum Seth J., Catapano Alberico L., Chapman M. John, Defesche Joep C., Folco Emanuela, Freiberger Tomas, Genest Jacques, Hovingh G. Kees, Harada-Shiba Mariko, Humphries Steve E., Jackson Ann S., Mata Pedro, Moriarty Patrick M., Raal Frederick J., Al-Rasadi Khalid, Ray Kausik K., Reiner Zelijko, Sijbrands Eric J. G., Yamashita Shizuya Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society Severe Familial Hypercholesterolemia Panel Lancet. Diabetes and endocrinology 2016;4 (10):850-861 [PubMed]
  • Hovingh G. Kees, Kastelein John J. P. Diagnosis and Management of Individuals With Heterozygous Familial Hypercholesterolemia: Too Late and Too Little Circulation 2016;134 (10):710-712 [PubMed]
  • Sjouke Barbara, Defesche Joep C., Hartgers Merel L., Wiegman Albert, Roeters van Lennep Jeanine E., Kastelein John J., Hovingh G. Kees Double-heterozygous autosomal dominant hypercholesterolemia: Clinical characterization of an underreported disease Journal of clinical lipidology 2016;10 (6):1462-1469 [PubMed]
  • Hovingh G. Kees, Kuivenhoven Jan Albert Editorial introductions Current opinion in lipidology 2016;27 (3):v
  • van Capelleveen Julian C., Kastelein John J. P., Zwinderman Aeilko H., van Deventer Sander J. H., Collins Heidi L., Adelman Steven J., Round Patrick, Ford John, Rader Daniel J., Hovingh G. Kees Effects of the cholesteryl ester transfer protein inhibitor, TA-8995, on cholesterol efflux capacity and high-density lipoprotein particle subclasses Journal of clinical lipidology 2016;10 (5):1137-1144.e3 [PubMed]
  • Ray Kausik K., Hovingh G. Kees Familial hypercholesterolaemia: a common disease European heart journal 2016;37 (17):1395-1397 [PubMed]
  • van Iperen Erik P. A., Sivapalaratnam Suthesh, Holmes Michael V., Hovingh G. Kees, Zwinderman Aeilko H., Asselbergs Folkert W. Genetic analysis of emerging risk factors in coronary artery disease Atherosclerosis 2016;254:35-41 [PubMed]
  • Stoekenbroek Robert M., Boekholdt S. Matthijs, Luben Robert, Hovingh G. Kees, Zwinderman Aeilko H., Wareham Nicholas J., Khaw Kay-Tee, Peters Ron J. G. Heterogeneous impact of classic atherosclerotic risk factors on different arterial territories: the EPIC-Norfolk prospective population study European heart journal 2016;37 (11):880-889 [PubMed]
  • Hovingh G. Kees, Gandra Shravanthi R., McKendrick Jan, Dent Ricardo, Wieffer Heather, Catapano Alberico L., Oh Paul, Rosenson Robert S., Stroes Erik S. Identification and management of patients with statin-associated symptoms in clinical practice: A clinician survey Atherosclerosis 2016;245:111-117 [PubMed]
  • Postmus Iris, Warren Helen R., Trompet Stella, Arsenault Benoit J., Avery Christy L., Bis Joshua C., Chasman Daniel I., de Keyser Catherine E., Deshmukh Harshal A., Evans Daniel S., Feng QiPing, Li Xiaohui, Smit Roelof A. J., Smith Albert V., Sun Fangui, Taylor Kent D., Arnold Alice M., Barnes Michael R., Barratt Bryan J., Betteridge John, Boekholdt S. Matthijs, Boerwinkle Eric, Buckley Brendan M., Chen Y.-D. Ida, de Craen Anton J. M., Cummings Steven R., Denny Joshua C., Dubé Marie Pierre, Durrington Paul N., Eiriksdottir Gudny, Ford Ian, Guo Xiuqing, Harris Tamara B., Heckbert Susan R., Hofman Albert, Hovingh G. Kees, Kastelein John J. P., Launer Leonore J., Liu Ching-Ti, Liu Yongmei, Lumley Thomas, McKeigue Paul M., Munroe Patricia B., Neil Andrew, Nickerson Deborah A., Nyberg Fredrik, O'Brien Eoin, O'Donnell Christopher J., Post Wendy, Poulter Neil, Vasan Ramachandran S., Rice Kenneth, Rich Stephen S., Rivadeneira Fernando, Sattar Naveed, Sever Peter, Shaw-Hawkins Sue, Shields Denis C., Slagboom P. Eline, Smith Nicholas L., Smith Joshua D., Sotoodehnia Nona, Stanton Alice, Stott David J., Stricker Bruno H., Stürmer Til, Uitterlinden André G., Wei Wei-Qi, Westendorp Rudi G. J., Whitsel Eric A., Wiggins Kerri L., Wilke Russell A., Ballantyne Christie M., Colhoun Helen M., Cupples L. Adrienne, Franco Oscar H., Gudnason Vilmundur, Hitman Graham, Palmer Colin N. A., Psaty Bruce M., Ridker Paul M., Stafford Jeanette M., Stein Charles M., Tardif Jean-Claude, Caulfield Mark J., Jukema J. Wouter, Rotter Jerome I., Krauss Ronald M. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins Journal of medical genetics 2016;53 (12):835-845 [PubMed]
  • Raal Frederick J., Sjouke Barbara, Hovingh G. Kees, Isaac Barton F. Phenotype diversity among patients with homozygous familial hypercholesterolemia: A cohort study Atherosclerosis 2016;248:238-244 [PubMed]
  • Vallejo-Vaz Antonio J., Akram Asif, Kondapally Seshasai Sreenivasa Rao, Cole Della, Watts Gerald F., Hovingh G. Kees, Kastelein John J. P., Mata Pedro, Raal Frederick J., Santos Raul D., Soran Handrean, Freiberger Tomas, Abifadel Marianne, Aguilar-Salinas Carlos A., Alnouri Fahad, Alonso Rodrigo, Al-Rasadi Khalid, Banach Maciej, Bogsrud Martin P., Bourbon Mafalda, Bruckert Eric, Car Josip, Ceska Richard, Corral Pablo, Descamps Olivier, Dieplinger Hans, Do Can T., Durst Ronen, Ezhov Marat V., Fras Zlatko, Gaita Dan, Gaspar Isabel M., Genest Jaques, Harada-Shiba Mariko, Jiang Lixin, Kayikcioglu Meral, Lam Carolyn S. P., Latkovskis Gustavs, Laufs Ulrich, Liberopoulos Evangelos, Lin Jie, Lin Nan, Maher Vincent, Majano Nelson, Marais A. David, März Winfried, Mirrakhimov Erkin, Miserez André R., Mitchenko Olena, Nawawi Hapizah, Nilsson Lennart, Nordestgaard Børge G., Paragh György, Petrulioniene Zaneta, Pojskic Belma, Reiner Željko, Sahebkar Amirhossein, Santos Lourdes E., Schunkert Heribert, Shehab Abdullah, Slimane M. Naceur, Stoll Mario, Su Ta-Chen, Susekov Andrey, Tilney Myra, Tomlinson Brian, Tselepis Alexandros D., Vohnout Branislav, Widén Elisabeth, Yamashita Shizuya, Catapano Alberico L., Ray Kausik K. Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration Atherosclerosis. Supplements 2016;22:1-32 [PubMed]
  • Verbeek Rutger, Boekholdt S. Matthijs, Stoekenbroek Robert M., Hovingh G. Kees, Witztum Joseph L., Wareham Nicholas J., Sandhu Manjinder S., Khaw Kay-Tee, Tsimikas Sotirios Population and assay thresholds for the predictive value of lipoprotein (a) for coronary artery disease: the EPIC-Norfolk Prospective Population Study Journal of lipid research 2016;57 (4):697-705 [PubMed]
  • Thedrez Aurélie, Sjouke Barbara, Passard Maxime, Prampart-Fauvet Simon, Guédon Alexis, Croyal Mikael, Dallinga-Thie Geesje, Peter Jorge, Blom Dirk, Ciccarese Milco, Cefalù Angelo B., Pisciotta Livia, Santos Raul D., Averna Maurizio, Raal Frederick, Pintus Paolo, Cossu Maria, Hovingh Kees, Lambert Gilles Proprotein Convertase Subtilisin Kexin Type 9 Inhibition for Autosomal Recessive Hypercholesterolemia-Brief Report Arteriosclerosis, thrombosis, and vascular biology 2016;36 (8):1647-1650 [PubMed]
  • Zanoni Paolo, Khetarpal Sumeet A., Larach Daniel B., Hancock-Cerutti William F., Millar John S., Cuchel Marina, DerOhannessian Stephanie, Kontush Anatol, Surendran Praveen, Saleheen Danish, Trompet Stella, Jukema J. Wouter, de Craen Anton, Deloukas Panos, Sattar Naveed, Ford Ian, Packard Chris, Majumder Abdullah al Shafi, Alam Dewan S., Di Angelantonio Emanuele, Abecasis Goncalo, Chowdhury Rajiv, Erdmann Jeanette, Nordestgaard Børge G., Nielsen Sune F., Tybjærg-Hansen Anne, Schmidt Ruth Frikke, Kuulasmaa Kari, Liu Dajiang J., Perola Markus, Blankenberg Stefan, Salomaa Veikko, Männistö Satu, Amouyel Philippe, Arveiler Dominique, Ferrieres Jean, Müller-Nurasyid Martina, Ferrario Marco, Kee Frank, Willer Cristen J., Samani Nilesh, Schunkert Heribert, Butterworth Adam S., Howson Joanna M. M., Peloso Gina M., Stitziel Nathan O., Danesh John, Kathiresan Sekar, Kastelein John J. P., Hovingh G. Kees Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease Science 2016;351 (6278):1166-1171 [PubMed]
  • Raal Frederick J., Sjouke Barbara, Hovingh G. Kees, Isaac Barton F. Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia Data in brief 2016;7:1458-1462 [PubMed]
  • Kastelein John J. P., Nissen Steven E., Rader Daniel J., Hovingh G. Kees, Wang Ming-Dauh, Shen Tong, Krueger Kathryn A. Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study European heart journal 2016;37 (17):1360-1369 [PubMed]
  • Sjouke Barbara, Defesche Joep C., de Randamie Janine S. E., Wiegman Albert, Fouchier Sigrid W., Hovingh G. Kees Sequencing for LIPA mutations in patients with a clinical diagnosis of familial hypercholesterolemia Atherosclerosis 2016;251:263-265 [PubMed]
  • Patel Manesh R., Armstrong Paul W., Bhatt Deepak L., Braunwald Eugene, Camm A. John, Fox Keith A. A., Harrington Robert A., Hiatt William R., James Stefan K., Kirtane Ajay J., Leon Martin B., Lincoff A. Michael, Mahaffey Kenneth W., Mauri Laura, Mehran Roxana, Mehta Shamir R., Montalescot Gilles, Nicholls Stephen J., Perkovic Vlado, Peterson Eric D., Pocock Stuart J., Roe Matthew T., Sabatine Marc S., Sekeres Mikkael, Solomon Scott D., Steg Gabriel, Stone Gregg W., van de Werf Frans, Wallentin Lars, White Harvey D., Gibson Michael, Gibson C. Michael, Achaval-Giraud Alberto, Aguilar Salinas Carlos A., Alexander John H., Almeida Eduardo Dytz, Ambrosio Giuseppe, Ann Robin, Annichino-Bizzacchi Joyce M., Antman Elliott, Antonescu Adrian, Antorrena-Miranda Isabel, Apartsin Konstantin, Arce Migdalia, Arellano-Rodrigo Eduardo, Assadourian Assadour, Astrahanceva Anastasija, Badings Erik, Hovingh G. K., Kastelein John Sharing Data from Cardiovascular Clinical Trials - A Proposal New England journal of medicine 2016;375 (5):407-409 [PubMed]
  • Besseling Joost, Hovingh G. Kees, Huijgen Roeland, Kastelein John J. P., Hutten Barbara A. Statins in Familial Hypercholesterolemia: Consequences for Coronary Artery Disease and All-Cause Mortality Journal of the American College of Cardiology 2016;68 (3):252-260 [PubMed]
  • Patel Aniruddh P., Peloso Gina M., Pirruccello James P., Johansen Christopher T., Dubé Joseph B., Larach Daniel B., Ban Matthew R., Dallinge-Thie Geesje M., Gupta Namrata, Boehnke Michael, Abecasis Gonçalo R., Kastelein John J. P., Hovingh G. Kees, Hegele Robert A., Rader Daniel J., Kathiresan Sekar Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution Atherosclerosis 2016;250:63-68 [PubMed]
  • Besseling Joost The extended phenotype of familial hypercholesterolemia 2016. 283p. ISBN 9789462333888. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kastelein J. J. P.; Co-supervisors: Hovingh G. K., Hutten B. A.)
  • Ehret Georg B., Ferreira Teresa, Chasman Daniel I., Jackson Anne U., Schmidt Ellen M., Johnson Toby, Thorleifsson Gudmar, Luan Jian'an, Donnelly Louise A., Kanoni Stavroula, Petersen Ann-Kristin, Pihur Vasyl, Strawbridge Rona J., Shungin Dmitry, Hughes Maria F., Meirelles Osorio, Kaakinen Marika, Bouatia-Naji Nabila, Kristiansson Kati, Shah Sonia, Kleber Marcus E., Guo Xiuqing, Lyytikäinen Leo-Pekka, Fava Cristiano, Eriksson Niclas, Nolte Ilja M., Magnusson Patrik K., Salfati Elias L., Rallidis Loukianos S., Theusch Elizabeth, Smith Andrew J. P., Folkersen Lasse, Witkowska Kate, Pers Tune H., Joehanes Roby, Kim Stuart K., Lataniotis Lazaros, Jansen Rick, Johnson Andrew D., Warren Helen, Kim Young Jin, Zhao Wei, Wu Ying, Tayo Bamidele O., Bochud Murielle, Absher Devin, Adair Linda S., Amin Najaf, Arking Dan E., Axelsson Tomas, Baldassarre Damiano, Balkau Beverley, Bandinelli Stefania, Barnes Michael R., Barroso Inês, Bevan Stephen, Bis Joshua C., Bjornsdottir Gyda, Boehnke Michael, Boerwinkle Eric, Bonnycastle Lori L., Boomsma Dorret I., Bornstein Stefan R., Brown Morris J., Burnier Michel, Cabrera Claudia P., Chambers John C., Chang I.-Shou, Cheng Ching-Yu, Chines Peter S., Chung Ren-Hua, Collins Francis S., Connell John M., Döring Angela, Dallongeville Jean, Danesh John, de Faire Ulf, Delgado Graciela, Dominiczak Anna F., Doney Alex S. F., Drenos Fotios, Edkins Sarah, Eicher John D., Elosua Roberto, Enroth Stefan, Erdmann Jeanette, Eriksson Per, Esko Tonu, Evangelou Evangelos, Evans Alun, Fall Tove, Farrall Martin, Felix Janine F., Ferrières Jean, Ferrucci Luigi, Fornage Myriam, Forrester Terrence, Franceschini Nora, Franco Oscar H., Franco-Cereceda Anders, Fraser Ross M., Ganesh Santhi K., Gao He, Gertow Karl, Gianfagna Francesco, Gigante Bruna, Giulianini Franco, Goel Anuj, Goodall Alison H., Goodarzi Mark O., Gorski Mathias, Gräßler Jürgen, Groves Christopher J., Gudnason Vilmundur, Gyllensten Ulf, Hallmans Göran, Hartikainen Anna-Liisa, Hassinen Maija, Havulinna Aki S., Hayward Caroline, Hercberg Serge, Herzig Karl-Heinz, Hicks Andrew A., Hingorani Aroon D., Hirschhorn Joel N., Hofman Albert, Holmen Jostein, Holmen Oddgeir Lingaas, Hottenga Jouke-Jan, Howard Phil, Hsiung Chao A., Hunt Steven C., Ikram M. Arfan, Illig Thomas, Iribarren Carlos, Jensen Richard A., Kähönen Mika, Kang Hyun Min, Kathiresan Sekar, Keating Brendan J., Khaw Kay-Tee, Kim Yun Kyoung, Kim Eric, Kivimaki Mika, Klopp Norman, Kolovou Genovefa, Komulainen Pirjo, Kooner Jaspal S., Kosova Gulum, Krauss Ronald M., Kuh Diana, Kutalik Zoltan, Kuusisto Johanna, Kvaløy Kirsti, Lakka Timo A., Lee Nanette R., Lee I.-Te, Lee Wen-Jane, Levy Daniel, Li Xiaohui, Liang Kae-Woei, Lin Honghuang, Lin Li, Lindström Jaana, Lobbens Stéphane, Männistö Satu, Müller Gabriele, Müller-Nurasyid Martina, Mach François, Markus Hugh S., Marouli Eirini, McCarthy Mark I., McKenzie Colin A., Meneton Pierre, Menni Cristina, Metspalu Andres, Mijatovic Vladan, Moilanen Leena, Montasser May E., Morris Andrew D., Morrison Alanna C., Mulas Antonella, Nagaraja Ramaiah, Narisu Narisu, Nikus Kjell, O'Donnell Christopher J., O'Reilly Paul F., Ong Ken K., Paccaud Fred, Palmer Cameron D., Parsa Afshin, Pedersen Nancy L., Penninx Brenda W., Perola Markus, Peters Annette, Poulter Neil, Pramstaller Peter P., Psaty Bruce M., Quertermous Thomas, Rao Dabeeru C., Rasheed Asif, Rayner N. William, Renström Frida, Rettig Rainer, Rice Kenneth M., Roberts Robert, Rose Lynda M., Rossouw Jacques, Samani Nilesh J., Sanna Serena, Saramies Jouko, Schunkert Heribert, Sebert Sylvain, Sheu Wayne H.-H., Shin Young-Ah, Sim Xueling, Smit Johannes H., Smith Albert V., Sosa Maria X., Spector Tim D., Stančáková Alena, Stanton Alice V., Stirrups Kathleen E., Stringham Heather M., Sundstrom Johan, Swift Amy J., Syvänen Ann-Christine, Tai E.-Shyong, Tanaka Toshiko, Tarasov Kirill V., Teumer Alexander, Thorsteinsdottir Unnur, Tobin Martin D., Tremoli Elena, Uitterlinden Andre G., Uusitupa Matti, Vaez Ahmad, Vaidya Dhananjay, van Duijn Cornelia M., van Iperen Erik P. A., Vasan Ramachandran S., Verwoert Germaine C., Virtamo Jarmo, Vitart Veronique, Voight Benjamin F., Vollenweider Peter, Wagner Aline, Wain Louise V., Wareham Nicholas J., Watkins Hugh, Weder Alan B., Westra Harm-Jan, Wilks Rainford, Wilsgaard Tom, Wilson James F., Wong Tien Y., Yang Tsun-Po, Yao Jie, Yengo Loic, Zhang Weihua, Zhao Jing Hua, Zhu Xiaofeng, Bovet Pascal, Cooper Richard S., Mohlke Karen L., Saleheen Danish, Lee Jong-Young, Elliott Paul, Gierman Hinco J., Willer Cristen J., Franke Lude, Hovingh G. Kees, Taylor Kent D., Dedoussis George, Sever Peter, Wong Andrew, Lind Lars, Assimes Themistocles L., Njølstad Inger, Schwarz Peter E. H., Langenberg Claudia, Snieder Harold, Caulfield Mark J., Melander Olle, Laakso Markku, Saltevo Juha, Rauramaa Rainer, Tuomilehto Jaakko, Ingelsson Erik, Lehtimäki Terho, Hveem Kristian, Palmas Walter, März Winfried, Kumari Meena, Salomaa Veikko, Chen Yii-der I., Rotter Jerome I., Froguel Philippe, Jarvelin Marjo-Riitta, Lakatta Edward G., Kuulasmaa Kari, Franks Paul W., Hamsten Anders, Wichmann H.-Erich, Palmer Colin N. A., Stefansson Kari, Ridker Paul M., Loos Ruth J. F., Chakravarti Aravinda, Deloukas Panos, Morris Andrew P., Newton-Cheh Christopher, Munroe Patricia B. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals Nature genetics 2016;48 (10):1171-1184 [PubMed]
  • Sahebkar Amirhossein, Serban Corina, Ursoniu Sorin, Mikhailidis Dimitri P., Undas Anetta, Lip Gregory Y. H., Bittner Vera, Ray Kausik, Watts Gerald F., Hovingh G. Kees, Rysz Jacek, Kastelein John J. P., Banach Maciej The impact of statin therapy on plasma levels of von Willebrand factor antigen. Systematic review and meta-analysis of randomised placebo-controlled trials Thrombosis and haemostasis 2016;115 (3):520-532 [PubMed]
  • Winkler Thomas W., Justice Anne E., Graff Mariaelisa, Barata Llilda, Feitosa Mary F., Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O., Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H., Rüeger Sina, Teumer Alexander, Ehret Georg B., Ferreira Teresa, Heard-Costa Nancy L., Karjalainen Juha, Lagou Vasiliki, Mahajan Anubha, Neinast Michael D., Prokopenko Inga, Simino Jeannette, Teslovich Tanya M., Jansen Rick, Westra Harm-Jan, White Charles C., Absher Devin, Ahluwalia Tarunveer S., Ahmad Shafqat, Albrecht Eva, Alves Alexessander Couto, Bragg-Gresham Jennifer L., de Craen Anton J. M., Bis Joshua C., Bonnefond Amélie, Boucher Gabrielle, Cadby Gemma, Cheng Yu-Ching, Chiang Charleston W. K., Delgado Graciela, Demirkan Ayse, Dueker Nicole, Eklund Niina, Eiriksdottir Gudny, Eriksson Joel, Feenstra Bjarke, Fischer Krista, Frau Francesca, Galesloot Tessel E., Geller Frank, Goel Anuj, Gorski Mathias, Grammer Tanja B., Gustafsson Stefan, Haitjema Saskia, Hottenga Jouke-Jan, Huffman Jennifer E., Jackson Anne U., Jacobs Kevin B., Johansson Åsa, Kaakinen Marika, Kleber Marcus E., Lahti Jari, Mateo Leach Irene, Lehne Benjamin, Liu Youfang, Lo Ken Sin, Lorentzon Mattias, Luan Jian'an, Madden Pamela A. F., Mangino Massimo, McKnight Barbara, Medina-Gomez Carolina, Monda Keri L., Montasser May E., Müller Gabriele, Müller-Nurasyid Martina, Nolte Ilja M., Panoutsopoulou Kalliope, Pascoe Laura, Paternoster Lavinia, Rayner Nigel W., Renström Frida, Rizzi Federica, Rose Lynda M., Ryan Kathy A., Salo Perttu, Sanna Serena, Scharnagl Hubert, Shi Jianxin, Smith Albert Vernon, Southam Lorraine, Stančáková Alena, Steinthorsdottir Valgerdur, Strawbridge Rona J., Sung Yun Ju, Tachmazidou Ioanna, Tanaka Toshiko, Thorleifsson Gudmar, Trompet Stella, Pervjakova Natalia, Tyrer Jonathan P., Vandenput Liesbeth, van der Laan Sander W., van der Velde Nathalie, van Setten Jessica, van Vliet-Ostaptchouk Jana V., Verweij Niek, Vlachopoulou Efthymia, Waite Lindsay L., Wang Sophie R., Wang Zhaoming, Wild Sarah H., Willenborg Christina, Wilson James F., Wong Andrew, Yang Jian, Yengo Loïc, Yerges-Armstrong Laura M., Yu Lei, Zhang Weihua, Zhao Jing Hua, Andersson Ehm A., Bakker Stephan J. L., Baldassarre Damiano, Banasik Karina, Barcella Matteo, Barlassina Cristina, Bellis Claire, Benaglio Paola, Blangero John, Blüher Matthias, Bonnet Fabrice, Bonnycastle Lori L., Boyd Heather A., Bruinenberg Marcel, Buchman Aron S., Campbell Harry, Chen Yii-Der Ida, Chines Peter S., Claudi-Boehm Simone, Cole John, Collins Francis S., de Geus Eco J. C., de Groot Lisette C. P. G. M., Dimitriou Maria, Duan Jubao, Enroth Stefan, Eury Elodie, Farmaki Aliki-Eleni, Forouhi Nita G., Friedrich Nele, Gejman Pablo V., Gigante Bruna, Glorioso Nicola, Go Alan S., Gottesman Omri, Gräßler Jürgen, Grallert Harald, Grarup Niels, Gu Yu-Mei, Broer Linda, Ham Annelies C., Hansen Torben, Harris Tamara B., Hartman Catharina A., Hassinen Maija, Hastie Nicholas, Hattersley Andrew T., Heath Andrew C., Henders Anjali K., Hernandez Dena, Hillege Hans, Holmen Oddgeir, Hovingh Kees G., Hui Jennie, Husemoen Lise L., Hutri-Kähönen Nina, Hysi Pirro G., Illig Thomas, de Jager Philip L., Jalilzadeh Shapour, Jørgensen Torben, Jukema J. Wouter, Juonala Markus, Kanoni Stavroula, Karaleftheri Maria, Khaw Kay Tee, Kinnunen Leena, Kittner Steven J., Koenig Wolfgang, Kolcic Ivana, Kovacs Peter, Krarup Nikolaj T., Kratzer Wolfgang, Krüger Janine, Kuh Diana, Kumari Meena, Kyriakou Theodosios, Langenberg Claudia, Lannfelt Lars, Lanzani Chiara, Lotay Vaneet, Launer Lenore J., Leander Karin, Lindström Jaana, Linneberg Allan, Liu Yan-Ping, Lobbens Stéphane, Luben Robert, Lyssenko Valeriya, Männistö Satu, Magnusson Patrik K., McArdle Wendy L., Menni Cristina, Merger Sigrun, Milani Lili, Montgomery Grant W., Morris Andrew P., Narisu Narisu, Nelis Mari, Ong Ken K., Palotie Aarno, Pérusse Louis, Pichler Irene, Pilia Maria G., Pouta Anneli, Rheinberger Myriam, Ribel-Madsen Rasmus, Richards Marcus, Rice Kenneth M., Rice Treva K., Rivolta Carlo, Salomaa Veikko, Sanders Alan R., Sarzynski Mark A., Scholtens Salome, Scott Robert A., Scott William R., Sebert Sylvain, Sengupta Sebanti, Sennblad Bengt, Seufferlein Thomas, Silveira Angela, Slagboom P. Eline, Smit Jan H., Sparsø Thomas H., Stirrups Kathleen, Stolk Ronald P., Stringham Heather M., Swertz Morris A., Swift Amy J., Syvänen Ann-Christine, Tan Sian-Tsung, Thorand Barbara, Tönjes Anke, Tremblay Angelo, Tsafantakis Emmanouil, van der Most Peter J., Völker Uwe, Vohl Marie-Claude, Vonk Judith M., Waldenberger Melanie, Walker Ryan W., Wennauer Roman, Widén Elisabeth, Willemsen Gonneke, Wilsgaard Tom, Wright Alan F., Zillikens M. Carola, van Dijk Suzanne C., van Schoor Natasja M., Asselbergs Folkert W., de Bakker Paul I. W., Beckmann Jacques S., Beilby John, Bennett David A., Bergman Richard N., Bergmann Sven, Böger Carsten A., Boehm Bernhard O., Boerwinkle Eric, Boomsma Dorret I., Bornstein Stefan R., Bottinger Erwin P., Bouchard Claude, Chambers John C., Chanock Stephen J., Chasman Daniel I., Cucca Francesco, Cusi Daniele, Dedoussis George, Erdmann Jeanette, Eriksson Johan G., Evans Denis A., de Faire Ulf, Farrall Martin, Ferrucci Luigi, Ford Ian, Franke Lude, Franks Paul W., Froguel Philippe, Gansevoort Ron T., Gieger Christian, Grönberg Henrik, Gudnason Vilmundur, Gyllensten Ulf, Hall Per, Hamsten Anders, van der Harst Pim, Hayward Caroline, Heliövaara Markku, Hengstenberg Christian, Hicks Andrew A., Hingorani Aroon, Hofman Albert, Hu Frank, Huikuri Heikki V., Hveem Kristian, James Alan L., Jordan Joanne M., Jula Antti, Kähönen Mika, Kajantie Eero, Kathiresan Sekar, Kiemeney Lambertus A. L. M., Kivimaki Mika, Knekt Paul B., Koistinen Heikki A., Kooner Jaspal S., Koskinen Seppo, Kuusisto Johanna, Maerz Winfried, Martin Nicholas G., Laakso Markku, Lakka Timo A., Lehtimäki Terho, Lettre Guillaume, Levinson Douglas F., Lind Lars, Lokki Marja-Liisa, Mäntyselkä Pekka, Melbye Mads, Metspalu Andres, Mitchell Braxton D., Moll Frans L., Murray Jeffrey C., Musk Arthur W., Nieminen Markku S., Njølstad Inger, Ohlsson Claes, Oldehinkel Albertine J., Oostra Ben A., Palmer Lyle J., Pankow James S., Pasterkamp Gerard, Pedersen Nancy L., Pedersen Oluf, Penninx Brenda W., Perola Markus, Peters Annette, Polašek Ozren, Pramstaller Peter P., Psaty Bruce M., Qi Lu, Quertermous Thomas, Raitakari Olli T., Rankinen Tuomo, Rauramaa Rainer, Ridker Paul M., Rioux John D., Rivadeneira Fernando, Rotter Jerome I., Rudan Igor, den Ruijter Hester M., Saltevo Juha, Sattar Naveed, Schunkert Heribert, Schwarz Peter E. H., Shuldiner Alan R., Sinisalo Juha, Snieder Harold, Sørensen Thorkild I. A., Spector Tim D., Staessen Jan A., Stefania Bandinelli, Thorsteinsdottir Unnur, Stumvoll Michael, Tardif Jean-Claude, Tremoli Elena, Tuomilehto Jaakko, Uitterlinden André G., Uusitupa Matti, Verbeek André L. M., Vermeulen Sita H., Viikari Jorma S., Vitart Veronique, Völzke Henry, Vollenweider Peter, Waeber Gérard, Walker Mark, Wallaschofski Henri, Wareham Nicholas J., Watkins Hugh, Zeggini Eleftheria, Chakravarti Aravinda, Clegg Deborah J., Cupples L. Adrienne, Gordon-Larsen Penny, Jaquish Cashell E., Rao D. C., Abecasis Goncalo R., Assimes Themistocles L., Barroso Inês, Berndt Sonja I., Boehnke Michael, Deloukas Panos, Fox Caroline S., Groop Leif C., Hunter David J., Ingelsson Erik, Kaplan Robert C., McCarthy Mark I., Mohlke Karen L., O'Connell Jeffrey R., Schlessinger David, Strachan David P., Stefansson Kari, van Duijn Cornelia M., Hirschhorn Joel N., Lindgren Cecilia M., Heid Iris M., North Kari E., Borecki Ingrid B., Kutalik Zoltán, Loos Ruth J. F. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (vol 11, e1005378, 2015) PLoS genetics 2016;12 (6):e1006166 [PubMed]

2015

  • Balder J. W., Scholtens S., de Vries J. K., van Schie L. M., Boekholdt S. M., Hovingh G. K., Kamphuisen P. W., Kuivenhoven J. A. Adherence to guidelines to prevent cardiovascular diseases: The LifeLines cohort study Netherlands journal of medicine 2015;73 (7):316-323 [PubMed]
  • Kastelein John J. P., Besseling Joost, Shah Sukrut, Bergeron Jean, Langslet Gisle, Hovingh G. Kees, Al-Saady Naab, Koeijvoets Michiel, Hunter John, Johnson-Levonas Amy O., Fable Jennifer, Sapre Aditi, Mitchel Yale Anacetrapib as lipid-modifying therapy in patients with heterozygous familial hypercholesterolaemia (REALIZE): a randomised, double-blind, placebo-controlled, phase 3 study Lancet 2015;385 (9983):2153-2161 [PubMed]
  • Michalska-Kasiczak Marta, Sahebkar Amirhossein, Mikhailidis Dimitri P., Rysz Jacek, Muntner Paul, Toth Peter P., Jones Steven R., Rizzo Manfredi, Kees Hovingh G., Farnier Michel, Moriarty Patrick M., Bittner Vera A., Lip Gregory Y. H., Banach Maciej Analysis of vitamin D levels in patients with and without statin-associated myalgia - a systematic review and meta-analysis of 7 studies with 2420 patients International journal of cardiology 2015;178:111-116 [PubMed]
  • Hiddink Larissa, Dallinga-Thie Geesje M., Hovingh G. Kees, de Visser Marieke C. H., Peer Petronella G. M., Stalenhoef Anton F. H., van Heerde Waander L. Annexin A5 haplotypes in familial hypercholesterolemia: lack of association with carotid intima-media thickness and cardiovascular disease risk Atherosclerosis 2015;238 (2):195-200 [PubMed]
  • Stoekenbroek R. M., Stroes E. S., Hovingh G. K. ApoA-I mimetics Handbook of experimental pharmacology 2015;224:631-648 [PubMed]
  • Besseling Joost, Kastelein John J. P., Defesche Joep C., Hutten Barbara A., Hovingh G. Kees Association Between Familial Hypercholesterolemia and Prevalence of Type 2 Diabetes Mellitus JAMA 2015;313 (10):1029-1036 [PubMed]
  • Sahebkar Amirhossein, Serban Corina, Mikhailidis Dimitri P., Undas Anetta, Lip Gregory Y. H., Muntner Paul, Bittner Vera, Ray Kausik K., Watts Gerald F., Hovingh G. Kees, Rysz Jacek, Kastelein John J. P., Banach Maciej Association between statin use and plasma D-dimer levels. A systematic review and meta-analysis of randomised controlled trials Thrombosis and haemostasis 2015;114 (3):546-557 [PubMed]
  • Schick Ursula M., Auer Paul L., Bis Joshua C., Lin Honghuang, Wei Peng, Pankratz Nathan, Lange Leslie A., Brody Jennifer, Stitziel Nathan O., Kim Daniel S., Carlson Christopher S., Fornage Myriam, Haessler Jeffery, Hsu Li, Jackson Rebecca D., Kooperberg Charles, Leal Suzanne M., Psaty Bruce M., Boerwinkle Eric, Tracy Russell, Ardissino Diego, Shah Svati, Willer Cristen, Loos Ruth, Melander Olle, McPherson Ruth, Hovingh Kees, Reilly Muredach, Watkins Hugh, Girelli Domenico, Fontanillas Pierre, Chasman Daniel I., Gabriel Stacey B., Gibbs Richard, Nickerson Deborah A., Kathiresan Sekar, Peters Ulrike, Dupuis Josée, Wilson James G., Rich Stephen S., Morrison Alanna C., Benjamin Emelia J., Gross Myron D., Reiner Alex P. Association of exome sequences with plasma C-reactive protein levels in >9000 participants Human molecular genetics 2015;24 (2):559-571 [PubMed]
  • Serban Corina, Sahebkar Amirhossein, Ursoniu Sorin, Mikhailidis Dimitri P., Rizzo Manfredi, Lip Gregory Y. H., Kees Hovingh G., Kastelein John J. P., Kalinowski Leszek, Rysz Jacek, Banach Maciej A systematic review and meta-analysis of the effect of statins on plasma asymmetric dimethylarginine concentrations Scientific reports 2015;5:9902 [PubMed]
  • Pers Tune H., Karjalainen Juha M., Chan Yingleong, Westra Harm-Jan, Wood Andrew R., Yang Jian, Lui Julian C., Vedantam Sailaja, Gustafsson Stefan, Esko Tonu, Frayling Tim, Speliotes Elizabeth K., Boehnke Michael, Raychaudhuri Soumya, Fehrmann Rudolf S. N., Hirschhorn Joel N., Franke Lude, Chu Audrey Y., Estrada Karol, Luan Jian'an, Kutalik Zoltán, Amin Najaf, Buchkovich Martin L., Croteau-Chonka Damien C., Day Felix R., Duan Yanan, Fall Tove, Fehrmann Rudolf, Ferreira Teresa, Jackson Anne U., Karjalainen Juha, Lo Ken Sin, Locke Adam E., Mägi Reedik, Mihailov Evelin, Porcu Eleonora, Randall Joshua C., Scherag André, Vinkhuyzen Anna A. E., Winkler Thomas W., Workalemahu Tsegaselassie, Zhao Jing Hua, Absher Devin, Albrecht Eva, Anderson Denise, Baron Jeffrey, Beekman Marian, van der Velde Nathalie, Hovingh G. Kees, Kastelein John J. P. Biological interpretation of genome-wide association studies using predicted gene functions Nature communications 2015;6:5890 [PubMed]
  • Hovingh G. Kees, Kastelein John J. P., van Deventer Sander J. H., Round Patrick, Ford John, Saleheen Danish, Rader Daniel J., Brewer H. Bryan, Barter Philip J. Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial Lancet 2015;386 (9992):452-460 [PubMed]
  • Burton Barbara K., Deegan Patrick B., Enns Gregory M., Guardamagna Ornella, Horslen Simon, Hovingh Gerard K., Lobritto Steve J., Malinova Vera, McLin Valerie A., Raiman Julian, Di Rocco Maja, Santra Saikat, Sharma Reena, Sykut-Cegielska Jolanta, Whitley Chester B., Eckert Stephen, Valayannopoulos Vassili, Quinn Anthony G. Clinical Features of Lysosomal Acid Lipase Deficiency Journal of pediatric gastroenterology and nutrition 2015;61 (6):619-625 [PubMed]
  • Hollak Carla E. M., Hovingh G. Kees Dyslipidaemia: Lysosomal acid lipase deficiency-a cautious leap forward Nature reviews. Endocrinology 2015;11 (12):696-697 [PubMed]
  • Kootte Ruud S., Smits Loek P., van der Valk Fleur M., Dasseux Jean-Louis, Keyserling Constance H., Barbaras Ronald, Paolini John F., Santos Raul D., van Dijk Theo H., Dallinga-van Thie Geesje M., Nederveen Aart J., Mulder Willem J. M., Hovingh G. Kees, Kastelein John J. P., Groen Albert K., Stroes Erik S. Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA Journal of lipid research 2015;56 (3):703-712 [PubMed]
  • Do Ron, Stitziel Nathan O., Won Hong-Hee, Jørgensen Anders Berg, Duga Stefano, Angelica Merlini Pier, Kiezun Adam, Farrall Martin, Goel Anuj, Zuk Or, Guella Illaria, Asselta Rosanna, Lange Leslie A., Peloso Gina M., Auer Paul L., Girelli Domenico, Martinelli Nicola, Farlow Deborah N., DePristo Mark A., Roberts Robert, Stewart Alexander F. R., Saleheen Danish, Danesh John, Epstein Stephen E., Sivapalaratnam Suthesh, Hovingh G. Kees, Kastelein John J., Samani Nilesh J., Schunkert Heribert, Erdmann Jeanette, Shah Svati H., Kraus William E., Davies Robert, Nikpay Majid, Johansen Christopher T., Wang Jian, Hegele Robert A., Hechter Eliana, Marz Winfried, Kleber Marcus E., Huang Jie, Johnson Andrew D., Li Mingyao, Burke Greg L., Gross Myron, Liu Yongmei, Assimes Themistocles L., Heiss Gerardo, Lange Ethan M., Folsom Aaron R. Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction Nature 2015;518 (7537):102-+ [PubMed]
  • Stitziel Nathan O., Peloso Gina M., Abifadel Marianne, Cefalu Angelo B., Fouchier Sigrid, Motazacker M. Mahdi, Tada Hayato, Larach Daniel B., Awan Zuhier, Haller Jorge F., Pullinger Clive R., Varret Mathilde, Rabès Jean-Pierre, Noto Davide, Tarugi Patrizia, Kawashiri Masa-Aki, Nohara Atsushi, Yamagishi Masakazu, Risman Marjorie, deo Rahul, Ruel Isabelle, Shendure Jay, Nickerson Deborah A., Wilson James G., Rich Stephen S., Gupta Namrata, Farlow Deborah N., Neale Benjamin M., Daly Mark J., Kane John P., Freeman Mason W., Genest Jacques, Rader Daniel J., Mabuchi Hiroshi, Kastelein John J. P., Hovingh G. Kees, Averna Maurizio R., Gabriel Stacey, Boileau Catherine, Kathiresan Sekar Exome sequencing in suspected monogenic dyslipidemias Circulation. Cardiovascular genetics 2015;8 (2):343-350 [PubMed]
  • Vallejo-Vaz Antonio J., Kondapally Seshasai Sreenivasa Rao, Cole Della, Hovingh G. Kees, Kastelein John J. P., Mata Pedro, Raal Frederick J., Santos Raul D., Soran Handrean, Watts Gerald F., Abifadel Marianne, Aguilar-Salinas Carlos A., Akram Asif, Alnouri Fahad, Alonso Rodrigo, Al-Rasadi Khalid, Banach Maciej, Bogsrud Martin P., Bourbon Mafalda, Bruckert Eric, Car Josip, Corral Pablo, Descamps Olivier, Dieplinger Hans, Durst Ronen, Freiberger Tomas, Gaspar Isabel M., Genest Jaques, Harada-Shiba Mariko, Jiang Lixin, Kayikcioglu Meral, Lam Carolyn S. P., Latkovskis Gustavs, Laufs Ulrich, Liberopoulos Evangelos, Nilsson Lennart, Nordestgaard Børge G., O'Donoghue John M., Sahebkar Amirhossein, Schunkert Heribert, Shehab Abdulla, Stoll Mario, Su Ta-Chen, Susekov Andrey, Widén Elisabeth, Catapano Alberico L., Ray Kausik K. Familial hypercholesterolaemia: A global call to arms Atherosclerosis 2015;243 (1):257-259 [PubMed]
  • Wiegman Albert, Gidding Samuel S., Watts Gerald F., Chapman M. John, Ginsberg Henry N., Cuchel Marina, Ose Leiv, Averna Maurizio, Boileau Catherine, Borén Jan, Bruckert Eric, Catapano Alberico L., Defesche Joep C., Descamps Olivier S., Hegele Robert A., Hovingh G. Kees, Humphries Steve E., Kovanen Petri T., Kuivenhoven Jan Albert, Masana Luis, Nordestgaard Børge G., Pajukanta Päivi, Parhofer Klaus G., Raal Frederick J., Ray Kausik K., Santos Raul D., Stalenhoef Anton F. H., Steinhagen-Thiessen Elisabeth, Stroes Erik S., Taskinen Marja-Riitta, Tybjærg-Hansen Anne, Wiklund Olov Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment European heart journal 2015;36 (36):2425-2437 [PubMed]
  • Nelson Christopher P., Hamby Stephen E., Saleheen Danish, Hopewell Jenna C., Zeng Lingyao, Assimes Themistocles L., Kanoni Stavroula, Willenborg Christina, Burgess Stephen, Amouyel Phillipe, Anand Sonia, Blankenberg Stefan, Boehm Bernhard O., Clarke Robert J., Collins Rory, Dedoussis George, Farrall Martin, Franks Paul W., Groop Leif, Hall Alistair S., Hamsten Anders, Hengstenberg Christian, Hovingh G. Kees, Ingelsson Erik, Kathiresan Sekar, Kee Frank, König Inke R., Kooner Jaspal, Lehtimäki Terho, März Winifred, McPherson Ruth, Metspalu Andres, Nieminen Markku S., O'Donnell Christopher J., Palmer Colin N. A., Peters Annette, Perola Markus, Reilly Muredach P., Ripatti Samuli, Roberts Robert, Salomaa Veikko, Shah Svati H., Schreiber Stefan, Siegbahn Agneta, Thorsteinsdottir Unnur, Veronesi Giovani, Wareham Nicholas, Willer Cristen J., Zalloua Pierre A., Erdmann Jeanette Genetically Determined Height and Coronary Artery Disease New England journal of medicine 2015;372 (17):1608-1618 [PubMed]
  • Gaulton Kyle J., Ferreira Teresa, Lee Yeji, Raimondo Anne, Mägi Reedik, Reschen Michael E., Mahajan Anubha, Locke Adam, Rayner N. William, Robertson Neil, Scott Robert A., Prokopenko Inga, Scott Laura J., Green Todd, Sparso Thomas, Thuillier Dorothee, Yengo Loic, Grallert Harald, Wahl Simone, Frånberg Mattias, Strawbridge Rona J., Kestler Hans, Chheda Himanshu, Eisele Lewin, Gustafsson Stefan, Steinthorsdottir Valgerdur, Thorleifsson Gudmar, Qi Lu, Karssen Lennart C., van Leeuwen Elisabeth M., Willems Sara M., Li Man, Chen Han, Fuchsberger Christian, Kwan Phoenix, Ma Clement, Linderman Michael, Lu Yingchang, Thomsen Soren K., Rundle Jana K., Beer Nicola L., van de Bunt Martijn, Chalisey Anil, Kang Hyun Min, Voight Benjamin F., Abecasis Gonçalo R., Almgren Peter, Baldassarre Damiano, Hovingh Kees, Trip Mieke D. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci Nature genetics 2015;47 (12):1415-+ [PubMed]
  • Locke Adam E., Kahali Bratati, Berndt Sonja I., Justice Anne E., Pers Tune H., Day Felix R., Powell Corey, Vedantam Sailaja, Buchkovich Martin L., Yang Jian, Croteau-Chonka Damien C., Esko Tonu, Fall Tove, Ferreira Teresa, Gustafsson Stefan, Kutalik Zoltán, Luan Jian'an, Mägi Reedik, Randall Joshua C., Winkler Thomas W., Wood Andrew R., Workalemahu Tsegaselassie, Faul Jessica D., Smith Jennifer A., Hua Zhao Jing, Zhao Wei, Chen Jin, Fehrmann Rudolf, Hedman Åsa K., Karjalainen Juha, Schmidt Ellen M., Absher Devin, Amin Najaf, Anderson Denise, Beekman Marian, Bolton Jennifer L., Bragg-Gresham Jennifer L., Buyske Steven, Demirkan Ayse, Deng Guohong, Ehret Georg B., Feenstra Bjarke, Feitosa Mary F., Fischer Krista, Goel Anuj, Gong Jian, Jackson Anne U., Hovingh G. Kees, Kastelein John J. P., Chen Wei Genetic studies of body mass index yield new insights for obesity biology Nature 2015;518 (7538):197-U401 [PubMed]
  • Hovingh G. Kees, Rader Daniel J., Hegele Robert A. HDL re-examined Current opinion in lipidology 2015;26 (2):127-132 [PubMed]
  • Stoekenbroek Robert M., Boekholdt S. Matthijs, Fayyad Rana, Laskey Rachel, Tikkanen Matti J., Pedersen Terje R., Hovingh G. Kees High-dose atorvastatin is superior to moderate-dose simvastatin in preventing peripheral arterial disease Heart (British Cardiac Society) 2015;101 (5):356-362 [PubMed]
  • Cuchel Marina, Bruckert Eric, Ginsberg Henry N., Raal Frederick J., Santos Raul D., Hegele Robert A., Kuivenhoven Jan Albert, Nordestgaard Børge G., Descamps Olivier S., Steinhagen-Thiessen Elisabeth, Tybjaerg-Hansen Anne, Watts Gerald F., Averna Maurizio, Boileau Catherine, Borén Jan, Catapano Alberico L., Defesche Joep C., Hovingh G. Kees, Humphries Steve E., Kovanen Petri T., Masana Luis, Pajukanta Päivi, Parhofer Klaus G., Ray Kausik K., Stalenhoef Anton F. H., Stroes Erik, Taskinen Marja-Riitta, Wiegman Albert, Wiklund Olov, Chapman M. John, Bore'n Jan Homozigot ailevi hiperkolesterolemi: klinisyenlerin taniyi ve klinik yönetimi geliştirmelerine yönelik yeni anlayişlar ve rehberlik. Avrupa Ateroskleroz Derneği'nin Ailevi Hiperkolesterolemi Üzerine Uzlaşi Paneli yazili görüşü Türk Kardiyoloji Derneği arşivi 2015;43 (Suppl. 1):1-14 [PubMed]
  • Sjouke Barbara, Kusters D. Meeike, Kindt Iris, Besseling Joost, Defesche Joep C., Sijbrands Eric J. G., Roeters van Lennep Jeanine E., Stalenhoef Anton F. H., Wiegman Albert, de Graaf Jacqueline, Fouchier Sigrid W., Kastelein John J. P., Hovingh G. Kees Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome European heart journal 2015;36 (9):560-565 [PubMed]
  • Sjouke Barbara, Hovingh G. Kees, Kastelein John J. P., Stefanutti Claudia Homozygous autosomal dominant hypercholesterolaemia: prevalence, diagnosis, and current and future treatment perspectives Current opinion in lipidology 2015;26 (3):200-209 [PubMed]
  • Sjouke B., van der Stappen J. W. J., Groener J. E. M., Pepping A., Wevers R. A., Gouw A., Dikkeschei L. D., Mijnhout S., Hovingh G. K., Alleman M. A. Hypercholesterolaemia and hepatosplenomegaly: two manifestations of cholesteryl ester storage disease Netherlands journal of medicine 2015;73 (3):129-132 [PubMed]
  • Banach Maciej, Serban Corina, Sahebkar Amirhossein, Mikhailidis Dimitri P., Ursoniu Sorin, Ray Kausik K., Rysz Jacek, Toth Peter P., Muntner Paul, Mosteoru Svetlana, García-García Hector M., Hovingh G. Kees, Kastelein John J. P., Serruys Patrick W. Impact of statin therapy on coronary plaque composition: a systematic review and meta-analysis of virtual histology intravascular ultrasound studies BMC medicine 2015;13 (1):229 [PubMed]
  • Raal Frederick J., Honarpour Narimon, Blom Dirk J., Hovingh G. Kees, Xu Feng, Scott Rob, Wasserman Scott M., Stein Evan A., Descamps Olivier, Gaudet Daniel, Blaha Vladimir, Soska Vladimir, Zemek Stanislav, Bruckert Eric, Farnier Michel, Sampietro Tiziana, Jambart Selim, Abi-Fadel Marianne, Blom Dirk, Raal Frederick, Fuentes Jimenez Francisco, Karlezi Rodrigo Alberto Alonso, Vidal Pardo Jose Ignacio, Ginsberg Henry, Stein Evan, Turner Traci, Hennekens Charles H., Andreotti Felicita, Baigent Colin, Brown W. Virgil, Davis Barry, Wiviott Stephen D. Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial Lancet 2015;385 (9965):341-350 [PubMed]
  • Hovingh G. Kees, Ray Kausik K., Boekholdt S. Matthijs Is Cholesteryl Ester Transfer Protein Inhibition an Effective Strategy to Reduce Cardiovascular Risk? CETP as a Target to Lower CVD Risk: Suspension of Disbelief? Circulation 2015;132 (5):433-440 [PubMed]
  • Ljunggren Stefan A., Levels Johannes H. M., Hovingh Kees, Holleboom Adriaan G., Vergeer Menno, Argyri Letta, Gkolfinopoulou Christina, Chroni Angeliki, Sierts Jeroen A., Kastelein John J., Kuivenhoven Jan Albert, Lindahl Mats, Karlsson Helen Lipoprotein profiles in human heterozygote carriers of a functional mutation P297S in scavenger receptor class B1 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2015;1851 (12):1587-1595 [PubMed]
  • van Capelleveen Julian C., Kootte Ruud S., Hovingh G. Kees, Bochem Andrea E. Myocardial infarction in a 36-year-old man with combined ABCA1 and APOA-1 deficiency Journal of clinical lipidology 2015;9 (3):396-399 [PubMed]
  • Hartgers Merel L., Ray Kausik K., Hovingh G. Kees New Approaches in Detection and Treatment of Familial Hypercholesterolemia Current cardiology reports 2015;17 (12):109 [PubMed]
  • Shungin Dmitry, Winkler Thomas W., Croteau-Chonka Damien C., Ferreira Teresa, Locke Adam E., Mägi Reedik, Strawbridge Rona J., Pers Tune H., Fischer Krista, Justice Anne E., Workalemahu Tsegaselassie, Wu Joseph M. W., Buchkovich Martin L., Heard-Costa Nancy L., Roman Tamara S., Drong Alexander W., Song Ci, Gustafsson Stefan, Day Felix R., Esko Tonu, Fall Tove, Kutalik Zoltán, Luan Jian'an, Randall Joshua C., Scherag André, Vedantam Sailaja, Wood Andrew R., Chen Jin, Fehrmann Rudolf, Karjalainen Juha, Kahali Bratati, Liu Ching-Ti, Schmidt Ellen M., Absher Devin, Amin Najaf, Anderson Denise, Beekman Marian, Bragg-Gresham Jennifer L., Buyske Steven, Demirkan Ayse, Ehret Georg B., Feitosa Mary F., Goel Anuj, Jackson Anne U., Johnson Toby, Kleber Marcus E., Henneman Peter, Hovingh G. Kees, Kastelein John J. P., Chen Wei New genetic loci link adipose and insulin biology to body fat distribution Nature 2015;518 (7538):187-U378 [PubMed]
  • Verbeek Rutger, Hovingh G. Kees, Boekholdt S. Matthijs Non-high-density lipoprotein cholesterol: current status as cardiovascular marker Current opinion in lipidology 2015;26 (6):502-510 [PubMed]
  • Kastelein John J. P., Ginsberg Henry N., Langslet Gisle, Hovingh G. Kees, Ceska Richard, Dufour Robert, Blom Dirk, Civeira Fernando, Krempf Michel, Lorenzato Christelle, Zhao Jian, Pordy Robert, Baccara-Dinet Marie T., Gipe Daniel A., Geiger Mary Jane, Farnier Michel ODYSSEY FH I and FH II: 78 week results with alirocumab treatment in 735 patients with heterozygous familial hypercholesterolaemia European heart journal 2015;36 (43):2996-3003 [PubMed]
  • Raal Frederick J., Stein Evan A., Dufour Robert, Turner Traci, Civeira Fernando, Burgess Lesley, Langslet Gisle, Scott Russell, Olsson Anders G., Sullivan David, Hovingh G. Kees, Cariou Bertrand, Gouni-Berthold Ioanna, Somaratne Ransi, Bridges Ian, Scott Rob, Wasserman Scott M., Gaudet Daniel, Watts Gerald, Frohlich Jiri, Hegele Robert, Genest Jacques, Bruckert Eric, Moulin Philippe, Steinhagen-Thiessen Elisabeth, Tomlinson Brian, Basart Dirk, Hermann Johannes, Janssen Stan, Kamphuisen Pieter, Rensma Pieter, Koster Ted, van de Wiel Albert, Blom Dirk, Jacovides Andrew, Raal Frederick, Karlezi Rodrigo, Alonso Alberto, Marin Luis Masana, Miranda Jose Lopez, Eriksson Mats, Olsson Anders, Miserez André, Kwok See, Le Roux Carel, Murthy Narasimha, Khan Michael, Wierzbicki Anthony, Stein Evan PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial Lancet 2015;385 (9965):331-340 [PubMed]
  • Verbeek Rutger, Stoekenbroek Robert M., Hovingh G. Kees PCSK9 inhibitors: Novel therapeutic agents for the treatment of hypercholesterolemia European journal of pharmacology 2015;763 (Part A):38-47 [PubMed]
  • de Backer Guy, Besseling Joost, Chapman John, Hovingh G. Kees, Kastelein John J. P., Kotseva Kornelia, Ray Kausik, Reiner Željko, Wood David, de Bacquer Dirk Prevalence and management of familial hypercholesterolaemia in coronary patients: An analysis of EUROASPIRE IV, a study of the European Society of Cardiology Atherosclerosis 2015;241 (1):169-175 [PubMed]
  • Maiwald Stephanie Rare genetic variants associated with early onset CVD 2015. 208p. ISBN 9789462037502. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Kastelein J. J. P., Ouwehand W. H.; Co-supervisors: Trip M. D., Dallinga-Thie G., Hovingh G. K.)
  • Boekholdt S. Matthijs, Hovingh G. Kees, Waters David D., Grundy Scott M., Kastelein John J. P. Reply: statin-induced low low-density lipoprotein cholesterol level: is lower better? Journal of the American College of Cardiology 2015;65 (1):109 [PubMed]
  • Stroes Erik S., Thompson Paul D., Corsini Alberto, Vladutiu Georgirene D., Raal Frederick J., Ray Kausik K., Roden Michael, Stein Evan, Tokgözoğlu Lale, Nordestgaard Børge G., Bruckert Eric, de Backer Guy, Krauss Ronald M., Laufs Ulrich, Santos Raul D., Hegele Robert A., Hovingh G. Kees, Leiter Lawrence A., Mach Francois, März Winfried, Newman Connie B., Wiklund Olov, Jacobson Terry A., Catapano Alberico L., Chapman M. John, Ginsberg Henry N., Leiter Lawrence Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management European heart journal 2015;36 (17):1012-1022 [PubMed]
  • Banach Maciej, Rizzo Manfredi, Toth Peter P., Farnier Michel, Davidson Michael H., Al-Rasadi Khalid, Aronow Wilbert S., Athyros Vasilis, Djuric Dragan M., Ezhov Marat V., Greenfield Robert S., Hovingh G. Kees, Kostner Karam, Serban Corina, Lighezan Daniel, Fras Zlatko, Moriarty Patrick M., Muntner Paul, Goudev Assen, Ceska Richard, Nicholls Stephen J., Broncel Marlena, Nikolic Dragana, Pella Daniel, Puri Raman, Rysz Jacek, Wong Nathan D., Bajnok Laszlo, Jones Steven R., Ray Kausik K., Mikhailidis Dimitri P. Statin intolerance - an attempt at a unified definition. Position paper from an International Lipid Expert Panel Archives of medical science 2015;11 (1):1-23 [PubMed]
  • Banach Maciej, Rizzo Manfredi, Toth Peter P., Farnier Michel, Davidson Michael H., Al-Rasadi Khalid, Aronow Wilbert S., Athyros Vasilis, Djuric Dragan M., Ezhov Marat V., Greenfield Robert S., Hovingh G. Kees, Kostner Karam, Serban Corina, Lighezan Daniel, Fras Zlatko, Moriarty Patrick M., Muntner Paul, Goudev Assen, Ceska Richard, Nicholls Stephen J., Broncel Marlena, Nikolic Dragana, Pella Daniel, Puri Raman, Rysz Jacek, Wong Nathan D., Bajnok Laszlo, Jones Steven R., Ray Kausik K., Mikhailidis Dimitri P. Statin intolerance - an attempt at a unified definition. Position paper from an International Lipid Expert Panel Expert opinion on drug safety 2015;14 (6):935-955 [PubMed]
  • Hovingh G. Kees, Smits Loek P., Stefanutti Claudia, Soran Handrean, Kwok See, de Graaf Jacqueline, Gaudet Daniel, Keyserling Constance H., Klepp Heather, Frick Jennifer, Paolini John F., Dasseux Jean-Louis, Kastelein John J. P., Stroes Erik S. The effect of an apolipoprotein A-I-containing high-density lipoprotein-mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholesterolemia: The Modifying Orphan Disease Evaluation (MODE) study American heart journal 2015;169 (5):736-742.e1 [PubMed]
  • Besseling Joost, Ong Kwok Leung, Huijgen Roeland, Rye Kerry-Anne, Hovingh G. Kees, Hutten Barbara A., Lambert Gilles The impact of LDLR function on fibroblast growth factor 21 levels Atherosclerosis 2015;241 (2):322-325 [PubMed]
  • Winkler Thomas W., Justice Anne E., Graff Mariaelisa, Barata Llilda, Feitosa Mary F., Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O., Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H., Rüeger Sina, Teumer Alexander, Ehret Georg B., Ferreira Teresa, Heard-Costa Nancy L., Karjalainen Juha, Lagou Vasiliki, Mahajan Anubha, Neinast Michael D., Prokopenko Inga, Simino Jeannette, Teslovich Tanya M., Jansen Rick, Westra Harm-Jan, White Charles C., Absher Devin, Ahluwalia Tarunveer S., Ahmad Shafqat, Albrecht Eva, Alves Alexessander Couto, Bragg-Gresham Jennifer L., de Craen Anton J. M., Bis Joshua C., Bonnefond Amélie, Boucher Gabrielle, Cadby Gemma, Cheng Yu-Ching, Chiang Charleston W. K., Delgado Graciela, Demirkan Ayse, Dueker Nicole, Eklund Niina, Eiriksdottir Gudny, Eriksson Joel, Feenstra Bjarke, Fischer Krista, Frau Francesca, Galesloot Tessel E., Geller Frank, Goel Anuj, Gorski Mathias, Grammer Tanja B., Gustafsson Stefan, Haitjema Saskia, Hottenga Jouke-Jan, Huffman Jennifer E., Jackson Anne U., Jacobs Kevin B., Johansson Åsa, Kaakinen Marika, Kleber Marcus E., Lahti Jari, Mateo Leach Irene, Lehne Benjamin, Liu Youfang, Lo Ken Sin, Lorentzon Mattias, Luan Jian'an, Madden Pamela A. F., Mangino Massimo, McKnight Barbara, Medina-Gomez Carolina, Monda Keri L., Montasser May E., Müller Gabriele, Müller-Nurasyid Martina, Nolte Ilja M., Panoutsopoulou Kalliope, Pascoe Laura, Paternoster Lavinia, Rayner Nigel W., Renström Frida, Rizzi Federica, Rose Lynda M., Ryan Kathy A., Salo Perttu, Sanna Serena, Scharnagl Hubert, Shi Jianxin, Smith Albert Vernon, Southam Lorraine, Stančáková Alena, Steinthorsdottir Valgerdur, Strawbridge Rona J., Sung Yun Ju, Tachmazidou Ioanna, Tanaka Toshiko, Thorleifsson Gudmar, Trompet Stella, Pervjakova Natalia, Tyrer Jonathan P., Vandenput Liesbeth, van der Laan Sander W., van der Velde Nathalie, van Setten Jessica, van Vliet-Ostaptchouk Jana V., Verweij Niek, Vlachopoulou Efthymia, Waite Lindsay L., Wang Sophie R., Wang Zhaoming, Wild Sarah H., Willenborg Christina, Wilson James F., Wong Andrew, Yang Jian, Yengo Loïc, Yerges-Armstrong Laura M., Yu Lei, Zhang Weihua, Zhao Jing Hua, Andersson Ehm A., Bakker Stephan J. L., Baldassarre Damiano, Banasik Karina, Barcella Matteo, Barlassina Cristina, Bellis Claire, Benaglio Paola, Blangero John, Blüher Matthias, Bonnet Fabrice, Bonnycastle Lori L., Boyd Heather A., Bruinenberg Marcel, Buchman Aron S., Campbell Harry, Chen Yii-Der Ida, Chines Peter S., Claudi-Boehm Simone, Cole John, Collins Francis S., de Geus Eco J. C., de Groot Lisette C. P. G. M., Dimitriou Maria, Duan Jubao, Enroth Stefan, Eury Elodie, Farmaki Aliki-Eleni, Forouhi Nita G., Friedrich Nele, Gejman Pablo V., Gigante Bruna, Glorioso Nicola, Go Alan S., Gottesman Omri, Gräßler Jürgen, Grallert Harald, Grarup Niels, Gu Yu-Mei, Broer Linda, Ham Annelies C., Hansen Torben, Harris Tamara B., Hartman Catharina A., Hassinen Maija, Hastie Nicholas, Hattersley Andrew T., Heath Andrew C., Henders Anjali K., Hernandez Dena, Hillege Hans, Holmen Oddgeir, Hovingh Kees G., Hui Jennie, Husemoen Lise L., Hutri-Kähönen Nina, Hysi Pirro G., Illig Thomas, de Jager Philip L., Jalilzadeh Shapour, Jørgensen Torben, Jukema J. Wouter, Juonala Markus, Kanoni Stavroula, Karaleftheri Maria, Khaw Kay Tee, Kinnunen Leena, Kittner Steven J., Koenig Wolfgang, Kolcic Ivana, Kovacs Peter, Krarup Nikolaj T., Kratzer Wolfgang, Krüger Janine, Kuh Diana, Kumari Meena, Kyriakou Theodosios, Langenberg Claudia, Lannfelt Lars, Lanzani Chiara, Lotay Vaneet, Launer Lenore J., Leander Karin, Lindström Jaana, Linneberg Allan, Liu Yan-Ping, Lobbens Stéphane, Luben Robert, Lyssenko Valeriya, Männistö Satu, Magnusson Patrik K., McArdle Wendy L., Menni Cristina, Merger Sigrun, Milani Lili, Montgomery Grant W., Morris Andrew P., Narisu Narisu, Nelis Mari, Ong Ken K., Palotie Aarno, Pérusse Louis, Pichler Irene, Pilia Maria G., Pouta Anneli, Rheinberger Myriam, Ribel-Madsen Rasmus, Richards Marcus, Rice Kenneth M., Rice Treva K., Rivolta Carlo, Salomaa Veikko, Sanders Alan R., Sarzynski Mark A., Scholtens Salome, Scott Robert A., Scott William R., Sebert Sylvain, Sengupta Sebanti, Sennblad Bengt, Seufferlein Thomas, Silveira Angela, Slagboom P. Eline, Smit Jan H., Sparsø Thomas H., Stirrups Kathleen, Stolk Ronald P., Stringham Heather M., Swertz Morris A., Swift Amy J., Syvänen Ann-Christine, Tan Sian-Tsung, Thorand Barbara, Tönjes Anke, Tremblay Angelo, Tsafantakis Emmanouil, van der Most Peter J., Völker Uwe, Vohl Marie-Claude, Vonk Judith M., Waldenberger Melanie, Walker Ryan W., Wennauer Roman, Widén Elisabeth, Willemsen Gonneke, Wilsgaard Tom, Wright Alan F., Zillikens M. Carola, van Dijk Suzanne C., van Schoor Natasja M., Asselbergs Folkert W., de Bakker Paul I. W., Beckmann Jacques S., Beilby John, Bennett David A., Bergman Richard N., Bergmann Sven, Böger Carsten A., Boehm Bernhard O., Boerwinkle Eric, Boomsma Dorret I., Bornstein Stefan R., Bottinger Erwin P., Bouchard Claude, Chambers John C., Chanock Stephen J., Chasman Daniel I., Cucca Francesco, Cusi Daniele, Dedoussis George, Erdmann Jeanette, Eriksson Johan G., Evans Denis A., de Faire Ulf, Farrall Martin, Ferrucci Luigi, Ford Ian, Franke Lude, Franks Paul W., Froguel Philippe, Gansevoort Ron T., Gieger Christian, Grönberg Henrik, Gudnason Vilmundur, Gyllensten Ulf, Hall Per, Hamsten Anders, van der Harst Pim, Hayward Caroline, Heliövaara Markku, Hengstenberg Christian, Hicks Andrew A., Hingorani Aroon, Hofman Albert, Hu Frank, Huikuri Heikki V., Hveem Kristian, James Alan L., Jordan Joanne M., Jula Antti, Kähönen Mika, Kajantie Eero, Kathiresan Sekar, Kiemeney Lambertus A. L. M., Kivimaki Mika, Knekt Paul B., Koistinen Heikki A., Kooner Jaspal S., Koskinen Seppo, Kuusisto Johanna, Maerz Winfried, Martin Nicholas G., Laakso Markku, Lakka Timo A., Lehtimäki Terho, Lettre Guillaume, Levinson Douglas F., Lind Lars, Lokki Marja-Liisa, Mäntyselkä Pekka, Melbye Mads, Metspalu Andres, Mitchell Braxton D., Moll Frans L., Murray Jeffrey C., Musk Arthur W., Nieminen Markku S., Njølstad Inger, Ohlsson Claes, Oldehinkel Albertine J., Oostra Ben A., Palmer Lyle J., Pankow James S., Pasterkamp Gerard, Pedersen Nancy L., Pedersen Oluf, Penninx Brenda W., Perola Markus, Peters Annette, Polašek Ozren, Pramstaller Peter P., Psaty Bruce M., Qi Lu, Quertermous Thomas, Raitakari Olli T., Rankinen Tuomo, Rauramaa Rainer, Ridker Paul M., Rioux John D., Rivadeneira Fernando, Rotter Jerome I., Rudan Igor, den Ruijter Hester M., Saltevo Juha, Sattar Naveed, Schunkert Heribert, Schwarz Peter E. H., Shuldiner Alan R., Sinisalo Juha, Snieder Harold, Sørensen Thorkild I. A., Spector Tim D., Staessen Jan A., Stefania Bandinelli, Thorsteinsdottir Unnur, Stumvoll Michael, Tardif Jean-Claude, Tremoli Elena, Tuomilehto Jaakko, Uitterlinden André G., Uusitupa Matti, Verbeek André L. M., Vermeulen Sita H., Viikari Jorma S., Vitart Veronique, Völzke Henry, Vollenweider Peter, Waeber Gérard, Walker Mark, Wallaschofski Henri, Wareham Nicholas J., Watkins Hugh, Zeggini Eleftheria, Chakravarti Aravinda, Clegg Deborah J., Cupples L. Adrienne, Gordon-Larsen Penny, Jaquish Cashell E., Rao D. C., Abecasis Goncalo R., Assimes Themistocles L., Barroso Inês, Berndt Sonja I., Boehnke Michael, Deloukas Panos, Fox Caroline S., Groop Leif C., Hunter David J., Ingelsson Erik, Kaplan Robert C., McCarthy Mark I., Mohlke Karen L., O'Connell Jeffrey R., Schlessinger David, Strachan David P., Stefansson Kari, van Duijn Cornelia M., Hirschhorn Joel N., Lindgren Cecilia M., Heid Iris M., North Kari E., Borecki Ingrid B., Kutalik Zoltán, Loos Ruth J. F. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study PLoS genetics 2015;11 (10):e1005378 [PubMed]
  • Koopal C., Retterstøl K., Sjouke B., Hovingh G. K., Ros E., de Graaf J., Dullaart R. P. F., Bertolini S., Visseren F. L. J. Vascular risk factors, vascular disease, lipids and lipid targets in patients with familial dysbetalipoproteinemia: a European cross-sectional study Atherosclerosis 2015;240 (1):90-97 [PubMed]

2014

  • Maiwald S., Oey R. C., Sivapalaratnam S., Bakhtiari K., Hovingh G. K., Basart D. C. G., Trip M. D., Dallinga-Thie G. M. Abnormal hemostatic parameters in patients with myocardial infarction but angiographically normal coronary arteries International journal of cardiology 2014;174 (3):734-735 [PubMed]
  • Bochem Andrea E., Holleboom Adriaan G., Romijn Johannes A., Hoekstra Menno, Dallinga Geesje M., Motazacker Mahdi M., Hovingh G. Kees, Kuivenhoven Jan A., Stroes Erik S. G. Adrenal Function in females with low plasma HDL-C due to mutations in ABCA1 and LCAT PLoS ONE 2014;9 (5):e90967 [PubMed]
  • Ljunggren Stefan, Levels Johannes H. M., Turkina Maria V., Sundberg Sofie, Bochem Andrea E., Hovingh Kees, Holleboom Adriaan G., Lindahl Mats, Kuivenhoven Jan Albert, Karlsson Helen ApoA-I mutations, L202P and K131del, in HDL from heterozygotes with low HDL-C Proteomics. Clinical applications 2014;8 (3-4):241-250 [PubMed]
  • van Iperen Erik P. A., Sivapalaratnam Suthesh, Boekholdt S. Matthijs, Hovingh G. Kees, Maiwald Stephanie, Tanck Michael W., Soranzo Nicole, Stephens Jonathan C., Sambrook Jennifer G., Levi Marcel, Ouwehand Willem H., Kastelein John Jp, Trip Mieke D., Zwinderman Aeilko H. Common genetic variants do not associate with CAD in familial hypercholesterolemia European journal of human genetics 2014;22 (6):809-813 [PubMed]
  • Wood Andrew R., Esko Tonu, Yang Jian, Vedantam Sailaja, Pers Tune H., Gustafsson Stefan, Chu Audrey Y., Estrada Karol, Luan Jian'an, Kutalik Zoltán, Amin Najaf, Buchkovich Martin L., Croteau-Chonka Damien C., Day Felix R., Duan Yanan, Fall Tove, Fehrmann Rudolf, Ferreira Teresa, Jackson Anne U., Karjalainen Juha, Lo Ken Sin, Locke Adam E., Mägi Reedik, Mihailov Evelin, Porcu Eleonora, Randall Joshua C., Scherag André, Vinkhuyzen Anna A. E., Westra Harm-Jan, Winkler Thomas W., Workalemahu Tsegaselassie, Zhao Jing Hua, Absher Devin, Albrecht Eva, Anderson Denise, Baron Jeffrey, Beekman Marian, Demirkan Ayse, Ehret Georg B., Feenstra Bjarke, Feitosa Mary F., Fischer Krista, Fraser Ross M., Goel Anuj, Gong Jian, Justice Anne E., Kanoni Stavroula, van der Velde Nathalie, Hovingh G. Kees, Kastelein John J. P. Defining the role of common variation in the genomic and biological architecture of adult human height Nature genetics 2014;46 (11):1173-1186 [PubMed]
  • Lim Elaine T., Würtz Peter, Havulinna Aki S., Palta Priit, Tukiainen Taru, Rehnström Karola, Esko Tõnu, Mägi Reedik, Inouye Michael, Lappalainen Tuuli, Chan Yingleong, Salem Rany M., Lek Monkol, Flannick Jason, Sim Xueling, Manning Alisa, Ladenvall Claes, Bumpstead Suzannah, Hämäläinen Eija, Aalto Kristiina, Maksimow Mikael, Salmi Marko, Blankenberg Stefan, Ardissino Diego, Shah Svati, Horne Benjamin, McPherson Ruth, Hovingh Gerald K., Reilly Muredach P., Watkins Hugh, Goel Anuj, Farrall Martin, Girelli Domenico, Reiner Alex P., Stitziel Nathan O., Kathiresan Sekar, Gabriel Stacey, Barrett Jeffrey C., Lehtimäki Terho, Laakso Markku, Groop Leif, Kaprio Jaakko, Perola Markus, McCarthy Mark I., Boehnke Michael, Altshuler David M., Lindgren Cecilia M., Hirschhorn Joel N., Metspalu Andres, Freimer Nelson B., Zeller Tanja, Jalkanen Sirpa, Koskinen Seppo, Raitakari Olli, Durbin Richard, MacArthur Daniel G., Salomaa Veikko, Ripatti Samuli, Daly Mark J., Palotie Aarno Distribution and medical impact of loss-of-function variants in the Finnish founder population PLoS genetics 2014;10 (7):e1004494 [PubMed]
  • Gomaraschi Monica, Ossoli Alice, Pozzi Silvia, Nilsson Peter, Cefalù Angelo B., Averna Maurizio, Kuivenhoven Jan Albert, Hovingh G. Kees, Veglia Fabrizio, Franceschini Guido, Calabresi Laura eNOS activation by HDL is impaired in genetic CETP deficiency PLoS ONE 2014;9 (5):e95925 [PubMed]
  • Sjouke Barbara, Langslet Gisle, Ceska Richard, Nicholls Stephen J., Nissen Steven E., Öhlander Maria, Ladenson Paul W., Olsson Anders G., Hovingh G. Kees, Kastelein John J. P. Eprotirome in patients with familial hypercholesterolaemia (the AKKA trial): a randomised, double-blind, placebo-controlled phase 3 study Lancet. Diabetes and endocrinology 2014;2 (6):455-463 [PubMed]
  • Tragante Vinicius, Barnes Michael R., Ganesh Santhi K., Lanktree Matthew B., Guo Wei, Franceschini Nora, Smith Erin N., Johnson Toby, Holmes Michael V., Padmanabhan Sandosh, Karczewski Konrad J., Almoguera Berta, Barnard John, Baumert Jens, Chang Yen-Pei Christy, Elbers Clara C., Farrall Martin, Fischer Mary E., Gaunt Tom R., Gho Johannes M. I. H., Gieger Christian, Goel Anuj, Gong Yan, Isaacs Aaron, Kleber Marcus E., Mateo Leach Irene, McDonough Caitrin W., Meijs Matthijs F. L., Melander Olle, Nelson Christopher P., Nolte Ilja M., Pankratz Nathan, Price Tom S., Shaffer Jonathan, Shah Sonia, Tomaszewski Maciej, van der Most Peter J., van Iperen Erik P. A., Vonk Judith M., Witkowska Kate, Wong Caroline O. L., Zhang Li, Beitelshees Amber L., Berenson Gerald S., Bhatt Deepak L., Brown Morris, Burt Amber, Cooper-DeHoff Rhonda M., Connell John M., Cruickshanks Karen J., Curtis Sean P., Davey-Smith George, Delles Christian, Gansevoort Ron T., Guo Xiuqing, Haiqing Shen, Hastie Claire E., Hofker Marten H., Hovingh G. Kees, Kim Daniel S., Kirkland Susan A., Klein Barbara E., Klein Ronald, Li Yun R., Maiwald Steffi, Newton-Cheh Christopher, O'Brien Eoin T., Onland-Moret N. Charlotte, Palmas Walter, Parsa Afshin, Penninx Brenda W., Pettinger Mary, Vasan Ramachandran S., Ranchalis Jane E., M Ridker Paul, Rose Lynda M., Sever Peter, Shimbo Daichi, Steele Laura, Stolk Ronald P., Thorand Barbara, Trip Mieke D., van Duijn Cornelia M., Verschuren W. Monique, Wijmenga Cisca, Wyatt Sharon, Young J. Hunter, Zwinderman Aeilko H., Bezzina Connie R., Boerwinkle Eric, Casas Juan P., Caulfield Mark J., Chakravarti Aravinda, Chasman Daniel I., Davidson Karina W., Doevendans Pieter A., Dominiczak Anna F., FitzGerald Garret A., Gums John G., Fornage Myriam, Hakonarson Hakon, Halder Indrani, Hillege Hans L., Illig Thomas, Jarvik Gail P., Johnson Julie A., Kastelein John J. P., Koenig Wolfgang, Kumari Meena, März Winfried, Murray Sarah S., O'Connell Jeffery R., Oldehinkel Albertine J., Pankow James S., Rader Daniel J., Redline Susan, Reilly Muredach P., Schadt Eric E., Kottke-Marchant Kandice, Snieder Harold, Snyder Michael, Stanton Alice V., Tobin Martin D., Uitterlinden André G., van der Harst Pim, van der Schouw Yvonne T., Samani Nilesh J., Watkins Hugh, Johnson Andrew D., Reiner Alex P., Zhu Xiaofeng, de Bakker Paul I. W., Levy Daniel, Asselbergs Folkert W., Munroe Patricia B., Keating Brendan J. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci American journal of human genetics 2014;94 (3):349-360 [PubMed]
  • Mahajan Anubha, Go Min Jin, Zhang Weihua, Below Jennifer E., Gaulton Kyle J., Ferreira Teresa, Horikoshi Momoko, Johnson Andrew D., Ng Maggie C. Y., Prokopenko Inga, Saleheen Danish, Wang Xu, Zeggini Eleftheria, Abecasis Goncalo R., Adair Linda S., Almgren Peter, Atalay Mustafa, Aung Tin, Baldassarre Damiano, Balkau Beverley, Bao Yuqian, Barnett Anthony H., Barroso Ines, Basit Abdul, Been Latonya F., Beilby John, Bell Graeme I., Benediktsson Rafn, Bergman Richard N., Boehm Bernhard O., Boerwinkle Eric, Bonnycastle Lori L., Burtt Noël, Cai Qiuyin, Campbell Harry, Carey Jason, Cauchi Stephane, Caulfield Mark, Chan Juliana C. N., Chang Li-Ching, Chang Tien-Jyun, Chang Yi-Cheng, Charpentier Guillaume, Chen Chien-Hsiun, Chen Han, Chen Yuan-Tsong, Chia Kee-Seng, Chidambaram Manickam, Hovingh Kees, Trip Mieke D. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility Nature genetics 2014;46 (3):234-244 [PubMed]
  • Rader Daniel J., Hovingh G. Kees HDL and cardiovascular disease Lancet 2014;384 (9943):618-625 [PubMed]
  • Colin Sophie, Fanchon Mélanie, Belloy Loic, Bochem Andrea E., Copin Corinne, Derudas Bruno, Stroes Erik S. G., Hovingh G. Kees, Kuivenhoven Jan A., Dallinga-Thie Geesje M., Staels Bart, Chinetti-Gbaguidi Giulia HDL does not influence the polarization of human monocytes toward an alternative phenotype International journal of cardiology 2014;172 (1):179-184 [PubMed]
  • Cuchel Marina, Bruckert Eric, Ginsberg Henry N., Raal Frederick J., Santos Raul D., Hegele Robert A., Kuivenhoven Jan Albert, Nordestgaard Børge G., Descamps Olivier S., Steinhagen-Thiessen Elisabeth, Tybjærg-Hansen Anne, Watts Gerald F., Averna Maurizio, Boileau Catherine, Borén Jan, Catapano Alberico L., Defesche Joep C., Hovingh G. Kees, Humphries Steve E., Kovanen Petri T., Masana Luis, Pajukanta Päivi, Parhofer Klaus G., Ray Kausik K., Stalenhoef Anton F. H., Stroes Erik, Taskinen Marja-Riitta, Wiegman Albert, Wiklund Olov, Chapman M. John Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society European heart journal 2014;35 (32):2146-2157 [PubMed]
  • Singaraja Roshni R., Tietjen Ian, Hovingh G. Kees, Franchini Patrick L., Radomski Chris, Wong Kenny, vanHeek Margaret, Stylianou Ioannis M., Lin Linus, Wang Liangsu, Mitnaul Lyndon, Hubbard Brian, Winther Michael, Mattice Maryanne, Legendre Annick, Sherrington Robin, Kastelein John J., Akinsanya Karen, Plump Andrew, Hayden Michael R. Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans Journal of lipid research 2014;55 (8):1693-1701 [PubMed]
  • Stitziel Nathan O., Won Hong-Hee, Morrison Alanna C., Peloso Gina M., Do Ron, Lange Leslie A., Fontanillas Pierre, Gupta Namrata, Duga Stefano, Goel Anuj, Farrall Martin, Saleheen Danish, Ferrario Paola, König Inke, Asselta Rosanna, Merlini Piera A., Marziliano Nicola, Notarangelo Maria Francesca, Schick Ursula, Auer Paul, Assimes Themistocles L., Reilly Muredach, Wilensky Robert, Rader Daniel J., Hovingh G. Kees, Meitinger Thomas, Kessler Thorsten, Kastrati Adnan, Laugwitz Karl-Ludwig, Siscovick David, Rotter Jerome I., Hazen Stanley L., Tracy Russell, Cresci Sharon, Spertus John, Jackson Rebecca, Schwartz Stephen M., Natarajan Pradeep, Crosby Jacy, Muzny Donna, Ballantyne Christie, Rich Stephen S., O'Donnell Christopher J., Abecasis Goncalo, Sunyaev Shamil, Nickerson Deborah A., Buring Julie E., Ridker Paul M., Chasman Daniel I., Austin Erin, Ye Zi, Kullo Iftikhar J., Weeke Peter E., Shaffer Christian M., Bastarache Lisa A., Denny Joshua C., Roden Dan M., Palmer Colin, Deloukas Panos, Lin Dan-Yu, Tang Zheng-zheng, Erdmann Jeanette, Schunkert Heribert, Danesh John, Marrugat Jaume, Elosua Roberto, Ardissino Diego, McPherson Ruth, Watkins Hugh, Reiner Alex P., Wilson James G., Altshuler David, Gibbs Richard A., Lander Eric S., Boerwinkle Eric, Gabriel Stacey, Kathiresan Sekar Inactivating mutations in NPC1L1 and protection from coronary heart disease New England journal of medicine 2014;371 (22):2072-2082 [PubMed]
  • Reiner Željko, Guardamagna Ornella, Nair Devaki, Soran Handrean, Hovingh Kees, Bertolini Stefano, Jones Simon, Ćorić Marijana, Calandra Sebastiano, Hamilton John, Eagleton Terence, Ros Emilio Lysosomal acid lipase deficiency--an under-recognized cause of dyslipidaemia and liver dysfunction Atherosclerosis 2014;235 (1):21-30 [PubMed]
  • Maiwald Stephanie, Sivapalaratnam Suthesh, Motazacker Mahdi M., van Capelleveen Julian C., Bot Ilze, de Jager Saskia C., van Eck Miranda, Jolley Jennifer, Kuiper Johan, Stephens Jonathon, Albers Cornelius A., Vosmeer C. Ruben, Kruize Heleen, Geerke Daan P., van der Wal Allard C., van der Loos Chris M., Kastelein John J. P., Trip Mieke D., Ouwehand Willem H., Dallinga-Thie Geesje M., Hovingh G. Kees Mutation in KERA identified by linkage analysis and targeted resequencing in a pedigree with premature atherosclerosis PLoS ONE 2014;9 (5):e98289 [PubMed]
  • Fouchier Sigrid W., Dallinga-Thie Geesje M., Meijers Joost C. M., Zelcer Noam, Kastelein John J. P., Defesche Joep C., Hovingh G. Kees Mutations in STAP1 are associated with autosomal dominant hypercholesterolemia Circulation research 2014;115 (6):552-555 [PubMed]
  • van Wijk Diederik F., Sjouke Barbara, Figueroa Amparo, Emami Hamed, van der Valk Fleur M., MacNabb Megan H., Hemphill Linda C., Schulte Dominik M., Koopman Marion G., Lobatto Mark E., Verberne Hein J., Fayad Zahi A., Kastelein John J. P., Mulder Willem J. M., Hovingh G. Kees, Tawakol Ahmed, Stroes Erik S. G. Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia Journal of the American College of Cardiology 2014;64 (14):1418-1426 [PubMed]
  • Hoggart Clive J., Venturini Giulia, Mangino Massimo, Gomez Felicia, Ascari Giulia, Zhao Jing Hua, Teumer Alexander, Winkler Thomas W., Tšernikova Natalia, Luan Jian'an, Mihailov Evelin, Ehret Georg B., Zhang Weihua, Lamparter David, Esko Tõnu, Macé Aurelien, Rüeger Sina, Bochud Pierre-Yves, Barcella Matteo, Dauvilliers Yves, Benyamin Beben, Evans David M., Hayward Caroline, Lopez Mary F., Franke Lude, Russo Alessia, Heid Iris M., Salvi Erika, Vendantam Sailaja, Arking Dan E., Boerwinkle Eric, Chambers John C., Fiorito Giovanni, Grallert Harald, Guarrera Simonetta, Homuth Georg, Huffman Jennifer E., Porteous David, Moradpour Darius, Iranzo Alex, Hebebrand Johannes, Kemp John P., Lammers Gert J., Aubert Vincent, Heim Markus H., Martin Nicholas G., Montgomery Grant W., Peraita-Adrados Rosa, Trip Mieke D., Hovingh Kees G. Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index PLoS genetics 2014;10 (7):e1004508 [PubMed]
  • van Capelleveen Julian C., Brewer H. Bryan, Kastelein John J. P., Hovingh G. Kees Novel Therapies Focused on the High-Density Lipoprotein Particle Circulation research 2014;114 (1):193-204 [PubMed]
  • Postmus Iris, Trompet Stella, Deshmukh Harshal A., Barnes Michael R., Li Xiaohui, Warren Helen R., Chasman Daniel I., Zhou Kaixin, Arsenault Benoit J., Donnelly Louise A., Wiggins Kerri L., Avery Christy L., Griffin Paula, Feng QiPing, Taylor Kent D., Li Guo, Evans Daniel S., Smith Albert V., de Keyser Catherine E., Johnson Andrew D., de Craen Anton J. M., Stott David J., Buckley Brendan M., Ford Ian, Westendorp Rudi G. J., Slagboom P. Eline, Sattar Naveed, Munroe Patricia B., Sever Peter, Poulter Neil, Stanton Alice, Shields Denis C., O'Brien Eoin, Shaw-Hawkins Sue, Chen Y.-D. Ida, Nickerson Deborah A., Smith Joshua D., Dubé Marie Pierre, Boekholdt S. Matthijs, Hovingh G. Kees, Kastelein John J. P., McKeigue Paul M., Betteridge John, Neil Andrew, Durrington Paul N., Doney Alex, Carr Fiona, Morris Andrew, McCarthy Mark I., Groop Leif Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins Nature communications 2014;5:5068 [PubMed]
  • Winkler Thomas W., Day Felix R., Croteau-Chonka Damien C., Wood Andrew R., Locke Adam E., Mägi Reedik, Ferreira Teresa, Fall Tove, Graff Mariaelisa, Justice Anne E., Luan Jian'an, Gustafsson Stefan, Randall Joshua C., Vedantam Sailaja, Workalemahu Tsegaselassie, Kilpeläinen Tuomas O., Scherag André, Esko Tonu, Kutalik Zoltán, Heid Iris M., Loos Ruth J. F., Abecasis Goncalo R., Absher Devin, Alavere Helene, Albrecht Eva, Allen Hana Lango, Almgren Peter, Amin Najaf, Amouyel Philippe, Anderson Denise, Arnold Alice M., Arveiler Dominique, Aspelund Thor, Asselbergs Folkert W., Assimes Themistocles L., Atalay Mustafa, Attwood Antony P., Atwood Larry D., Bakker Stephan J. L., Balkau Beverley, Balmforth Anthony J., Barlassina Cristina, Barroso Inês, Basart Hanneke, Bauer Sabrina, Beckmann Jacques S., Beilby John P., Bennett Amanda J., Hovingh Kees G., Trip Mieke D. Quality control and conduct of genome-wide association meta-analyses Nature protocols 2014;9 (5):1192-1212 [PubMed]
  • Besseling Joost, Kindt Iris, Hof Michel, Kastelein John J. P., Hutten Barbara A., Hovingh G. Kees Severe heterozygous familial hypercholesterolemia and risk for cardiovascular disease: a study of a cohort of 14,000 mutation carriers Atherosclerosis 2014;233 (1):219-223 [PubMed]
  • Bangalore Sripal, Fayyad Rana, Hovingh G. Kees, Laskey Rachel, Vogt Liffert, Demicco David A., Waters David D. Statin and the risk of renal-related serious adverse events: Analysis from the IDEAL, TNT, CARDS, ASPEN, SPARCL, and other placebo-controlled trials American journal of cardiology 2014;113 (12):2018-2020 [PubMed]
  • Hegele Robert A., Ginsberg Henry N., Chapman M. John, Nordestgaard Børge G., Kuivenhoven Jan Albert, Averna Maurizio, Borén Jan, Bruckert Eric, Catapano Alberico L., Descamps Olivier S., Hovingh G. Kees, Humphries Steve E., Kovanen Petri T., Masana Luis, Pajukanta Päivi, Parhofer Klaus G., Raal Frederick J., Ray Kausik K., Santos Raul D., Stalenhoef Anton F. H., Stroes Erik, Taskinen Marja-Riitta, Tybjærg-Hansen Anne, Watts Gerald F., Wiklund Olov The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management Lancet. Diabetes and endocrinology 2014;2 (8):655-666 [PubMed]
  • Duivenvoorden Raphael, Stroes Erik S. G., Hovingh G. Kees The value of screening for carotid plaque in patients referred for echocardiography Canadian journal of cardiology 2014;30 (10):1148-1149 [PubMed]
  • Dallinga-Thie G. M., Hovingh G. K. Towards network analysis to understand the genetic architecture of blood lipids: Do the inclusion of age-dependency helps to identify seven novel loci? Atherosclerosis 2014;235 (2):642-643 [PubMed]
  • Niesor Eric J., Kallend David, Bentley Darren, Kastelein John J. P., Kees Hovingh G., Stroes Erik S. G. Treatment of low HDL-C subjects with the CETP modulator dalcetrapib increases plasma campesterol only in those without ABCA1 and/or ApoA1 mutations Lipids 2014;49 (12):1245-1249 [PubMed]
  • Bochem A. E., van Capelleveen J. C., Dallinga-Thie G. M., Schimmel A. W. M., Motazacker M. M., Tietjen I., Singaraja R. R., Hayden M. R., Kastelein J. J. P., Stroes E. S. G., Hovingh G. K. Two novel mutations in apolipoprotein C3 underlie atheroprotective lipid profiles in families Clinical genetics 2014;85 (5):433-440 [PubMed]
  • Boekholdt S. Matthijs, Hovingh G. Kees, Mora Samia, Arsenault Benoit J., Amarenco Pierre, Pedersen Terje R., LaRosa John C., Waters David D., Demicco David A., Simes R. John, Keech Antony C., Colquhoun David, Hitman Graham A., Betteridge D. John, Clearfield Michael B., Downs John R., Colhoun Helen M., Gotto Antonio M., Ridker Paul M., Grundy Scott M., Kastelein John J. P. Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials Journal of the American College of Cardiology 2014;64 (5):485-494 [PubMed]

2013

  • Bochem Andrea E., van Wijk Diederik F., Holleboom Adriaan G., Duivenvoorden Raphaël, Motazacker Mahdi M., Dallinga-Thie Geesje M., de Groot Eric, Kastelein John J. P., Nederveen Aart J., Hovingh G. Kees, Stroes Erik S. G. ABCA1 mutation carriers with low high-density lipoprotein cholesterol are characterized by a larger atherosclerotic burden European heart journal 2013;34 (4):286-291 [PubMed]
  • Besseling J., Hovingh G. K., Stroes E. S. G. Antisense oligonucleotides in the treatment of lipid disorders: pitfalls and promises Netherlands journal of medicine 2013;71 (3):118-122 [PubMed]
  • Do Ron, Willer Cristen J., Schmidt Ellen M., Sengupta Sebanti, Gao Chi, Peloso Gina M., Gustafsson Stefan, Kanoni Stavroula, Ganna Andrea, Chen Jin, Buchkovich Martin L., Mora Samia, Beckmann Jacques S., Bragg-Gresham Jennifer L., Chang Hsing-Yi, Demirkan Ayşe, den Hertog Heleen M., Donnelly Louise A., Ehret Georg B., Esko Tõnu, Feitosa Mary F., Ferreira Teresa, Fischer Krista, Fontanillas Pierre, Fraser Ross M., Freitag Daniel F., Gurdasani Deepti, Heikkilä Kauko, Hyppönen Elina, Isaacs Aaron, Jackson Anne U., Johansson Asa, Johnson Toby, Kaakinen Marika, Kettunen Johannes, Kleber Marcus E., Li Xiaohui, Luan Jian'an, Lyytikäinen Leo-Pekka, Magnusson Patrik K. E., Mangino Massimo, Mihailov Evelin, Montasser May E., Müller-Nurasyid Martina, Nolte Ilja M., O'Connell Jeffrey R., Palmer Cameron D., Perola Markus, Petersen Ann-Kristin, Sanna Serena, Saxena Richa, Service Susan K., Shah Sonia, Shungin Dmitry, Sidore Carlo, Song Ci, Strawbridge Rona J., Surakka Ida, Tanaka Toshiko, Teslovich Tanya M., Thorleifsson Gudmar, van den Herik Evita G., Voight Benjamin F., Volcik Kelly A., Waite Lindsay L., Wong Andrew, Wu Ying, Zhang Weihua, Absher Devin, Asiki Gershim, Barroso Inês, Been Latonya F., Bolton Jennifer L., Bonnycastle Lori L., Brambilla Paolo, Burnett Mary S., Cesana Giancarlo, Dimitriou Maria, Doney Alex S. F., Döring Angela, Elliott Paul, Epstein Stephen E., Eyjolfsson Gudmundur Ingi, Gigante Bruna, Goodarzi Mark O., Grallert Harald, Gravito Martha L., Groves Christopher J., Hallmans Göran, Hartikainen Anna-Liisa, Hayward Caroline, Hernandez Dena, Hicks Andrew A., Holm Hilma, Hung Yi-Jen, Illig Thomas, Jones Michelle R., Kaleebu Pontiano, Kastelein John J. P., Khaw Kay-Tee, Kim Eric, Klopp Norman, Komulainen Pirjo, Kumari Meena, Langenberg Claudia, Lehtimäki Terho, Lin Shih-Yi, Lindström Jaana, Loos Ruth J. F., Mach François, McArdle Wendy L., Meisinger Christa, Mitchell Braxton D., Müller Gabrielle, Nagaraja Ramaiah, Narisu Narisu, Nieminen Tuomo V. M., Nsubuga Rebecca N., Olafsson Isleifur, Ong Ken K., Palotie Aarno, Papamarkou Theodore, Pomilla Cristina, Pouta Anneli, Rader Daniel J., Reilly Muredach P., Ridker Paul M., Rivadeneira Fernando, Rudan Igor, Ruokonen Aimo, Samani Nilesh, Scharnagl Hubert, Seeley Janet, Silander Kaisa, Stančáková Alena, Stirrups Kathleen, Swift Amy J., Tiret Laurence, Uitterlinden Andre G., van Pelt L. Joost, Vedantam Sailaja, Wainwright Nicholas, Wijmenga Cisca, Wild Sarah H., Willemsen Gonneke, Wilsgaard Tom, Wilson James F., Young Elizabeth H., Zhao Jing Hua, Adair Linda S., Arveiler Dominique, Assimes Themistocles L., Bandinelli Stefania, Bennett Franklyn, Bochud Murielle, Boehm Bernhard O., Boomsma Dorret I., Borecki Ingrid B., Bornstein Stefan R., Bovet Pascal, Burnier Michel, Campbell Harry, Chakravarti Aravinda, Chambers John C., Chen Yii-Der Ida, Collins Francis S., Cooper Richard S., Danesh John, Dedoussis George, de Faire Ulf, Feranil Alan B., Ferrières Jean, Ferrucci Luigi, Freimer Nelson B., Gieger Christian, Groop Leif C., Gudnason Vilmundur, Gyllensten Ulf, Hamsten Anders, Harris Tamara B., Hingorani Aroon, Hirschhorn Joel N., Hofman Albert, Hovingh G. Kees, Hsiung Chao Agnes, Humphries Steve E., Hunt Steven C., Hveem Kristian, Iribarren Carlos, Järvelin Marjo-Riitta, Jula Antti, Kähönen Mika, Kaprio Jaakko, Kesäniemi Antero, Kivimaki Mika, Kooner Jaspal S., Koudstaal Peter J., Krauss Ronald M., Kuh Diana, Kuusisto Johanna, Kyvik Kirsten O., Laakso Markku, Lakka Timo A., Lind Lars, Lindgren Cecilia M., Martin Nicholas G., März Winfried, McCarthy Mark I., McKenzie Colin A., Meneton Pierre, Metspalu Andres, Moilanen Leena, Morris Andrew D., Munroe Patricia B., Njølstad Inger, Pedersen Nancy L., Power Chris, Pramstaller Peter P., Price Jackie F., Psaty Bruce M., Quertermous Thomas, Rauramaa Rainer, Saleheen Danish, Salomaa Veikko, Sanghera Dharambir K., Saramies Jouko, Schwarz Peter E. H., Sheu Wayne H.-H., Shuldiner Alan R., Siegbahn Agneta, Spector Tim D., Stefansson Kari, Strachan David P., Tayo Bamidele O., Tremoli Elena, Tuomilehto Jaakko, Uusitupa Matti, van Duijn Cornelia M., Vollenweider Peter, Wallentin Lars, Wareham Nicholas J., Whitfield John B., Wolffenbuttel Bruce H. R., Altshuler David, Ordovas Jose M., Boerwinkle Eric, Palmer Colin N. A., Thorsteinsdottir Unnur, Chasman Daniel I., Rotter Jerome I., Franks Paul W., Ripatti Samuli, Cupples L. Adrienne, Sandhu Manjinder S., Rich Stephen S., Boehnke Michael, Deloukas Panos, Mohlke Karen L., Ingelsson Erik, Abecasis Goncalo R., Daly Mark J., Neale Benjamin M., Kathiresan Sekar Common variants associated with plasma triglycerides and risk for coronary artery disease Nature genetics 2013;45 (11):1345-1352 [PubMed]
  • Hovingh G. Kees, Davidson Michael H., Kastelein John J. P., O'Connor Anne M. Diagnosis and treatment of familial hypercholesterolaemia European heart journal 2013;34 (13):962-971 [PubMed]
  • Willer Cristen J., Schmidt Ellen M., Sengupta Sebanti, Peloso Gina M., Gustafsson Stefan, Kanoni Stavroula, Ganna Andrea, Chen Jin, Buchkovich Martin L., Mora Samia, Beckmann Jacques S., Bragg-Gresham Jennifer L., Chang Hsing-Yi, Demirkan Ayşe, den Hertog Heleen M., Do Ron, Donnelly Louise A., Ehret Georg B., Esko Tõnu, Feitosa Mary F., Ferreira Teresa, Fischer Krista, Fontanillas Pierre, Fraser Ross M., Freitag Daniel F., Gurdasani Deepti, Heikkilä Kauko, Hyppönen Elina, Isaacs Aaron, Jackson Anne U., Johansson Asa, Johnson Toby, Kaakinen Marika, Kettunen Johannes, Kleber Marcus E., Li Xiaohui, Luan Jian'an, Lyytikäinen Leo-Pekka, Magnusson Patrik K. E., Mangino Massimo, Mihailov Evelin, Montasser May E., Müller-Nurasyid Martina, Nolte Ilja M., O'Connell Jeffrey R., Palmer Cameron D., Perola Markus, Petersen Ann-Kristin, Sanna Serena, Saxena Richa, Service Susan K., Shah Sonia, Shungin Dmitry, Sidore Carlo, Song Ci, Strawbridge Rona J., Surakka Ida, Tanaka Toshiko, Teslovich Tanya M., Thorleifsson Gudmar, van den Herik Evita G., Voight Benjamin F., Volcik Kelly A., Waite Lindsay L., Wong Andrew, Wu Ying, Zhang Weihua, Absher Devin, Asiki Gershim, Barroso Inês, Been Latonya F., Bolton Jennifer L., Bonnycastle Lori L., Brambilla Paolo, Burnett Mary S., Cesana Giancarlo, Dimitriou Maria, Doney Alex S. F., Döring Angela, Elliott Paul, Epstein Stephen E., Eyjolfsson Gudmundur Ingi, Gigante Bruna, Goodarzi Mark O., Grallert Harald, Gravito Martha L., Groves Christopher J., Hallmans Göran, Hartikainen Anna-Liisa, Hayward Caroline, Hernandez Dena, Hicks Andrew A., Holm Hilma, Hung Yi-Jen, Illig Thomas, Jones Michelle R., Kaleebu Pontiano, Kastelein John J. P., Khaw Kay-Tee, Kim Eric, Klopp Norman, Komulainen Pirjo, Kumari Meena, Langenberg Claudia, Lehtimäki Terho, Lin Shih-Yi, Lindström Jaana, Loos Ruth J. F., Mach François, McArdle Wendy L., Meisinger Christa, Mitchell Braxton D., Müller Gabrielle, Nagaraja Ramaiah, Narisu Narisu, Nieminen Tuomo V. M., Nsubuga Rebecca N., Olafsson Isleifur, Ong Ken K., Palotie Aarno, Papamarkou Theodore, Pomilla Cristina, Pouta Anneli, Rader Daniel J., Reilly Muredach P., Ridker Paul M., Rivadeneira Fernando, Rudan Igor, Ruokonen Aimo, Samani Nilesh, Scharnagl Hubert, Seeley Janet, Silander Kaisa, Stancáková Alena, Stirrups Kathleen, Swift Amy J., Tiret Laurence, Uitterlinden Andre G., van Pelt L. Joost, Vedantam Sailaja, Wainwright Nicholas, Wijmenga Cisca, Wild Sarah H., Willemsen Gonneke, Wilsgaard Tom, Wilson James F., Young Elizabeth H., Zhao Jing Hua, Adair Linda S., Arveiler Dominique, Assimes Themistocles L., Bandinelli Stefania, Bennett Franklyn, Bochud Murielle, Boehm Bernhard O., Boomsma Dorret I., Borecki Ingrid B., Bornstein Stefan R., Bovet Pascal, Burnier Michel, Campbell Harry, Chakravarti Aravinda, Chambers John C., Chen Yii-Der Ida, Collins Francis S., Cooper Richard S., Danesh John, Dedoussis George, de Faire Ulf, Feranil Alan B., Ferrières Jean, Ferrucci Luigi, Freimer Nelson B., Gieger Christian, Groop Leif C., Gudnason Vilmundur, Gyllensten Ulf, Hamsten Anders, Harris Tamara B., Hingorani Aroon, Hirschhorn Joel N., Hofman Albert, Hovingh G. Kees, Hsiung Chao Agnes, Humphries Steve E., Hunt Steven C., Hveem Kristian, Iribarren Carlos, Järvelin Marjo-Riitta, Jula Antti, Kähönen Mika, Kaprio Jaakko, Kesäniemi Antero, Kivimaki Mika, Kooner Jaspal S., Koudstaal Peter J., Krauss Ronald M., Kuh Diana, Kuusisto Johanna, Kyvik Kirsten O., Laakso Markku, Lakka Timo A., Lind Lars, Lindgren Cecilia M., Martin Nicholas G., März Winfried, McCarthy Mark I., McKenzie Colin A., Meneton Pierre, Metspalu Andres, Moilanen Leena, Morris Andrew D., Munroe Patricia B., Njølstad Inger, Pedersen Nancy L., Power Chris, Pramstaller Peter P., Price Jackie F., Psaty Bruce M., Quertermous Thomas, Rauramaa Rainer, Saleheen Danish, Salomaa Veikko, Sanghera Dharambir K., Saramies Jouko, Schwarz Peter E. H., Sheu Wayne H.-H., Shuldiner Alan R., Siegbahn Agneta, Spector Tim D., Stefansson Kari, Strachan David P., Tayo Bamidele O., Tremoli Elena, Tuomilehto Jaakko, Uusitupa Matti, van Duijn Cornelia M., Vollenweider Peter, Wallentin Lars, Wareham Nicholas J., Whitfield John B., Wolffenbuttel Bruce H. R., Ordovas Jose M., Boerwinkle Eric, Palmer Colin N. A., Thorsteinsdottir Unnur, Chasman Daniel I., Rotter Jerome I., Franks Paul W., Ripatti Samuli, Cupples L. Adrienne, Sandhu Manjinder S., Rich Stephen S., Boehnke Michael, Deloukas Panos, Kathiresan Sekar, Mohlke Karen L., Ingelsson Erik, Abecasis Gonçalo R. Discovery and refinement of loci associated with lipid levels Nature genetics 2013;45 (11):1274-1283 [PubMed]
  • Hovingh Kees, Besseling Joost, Kastelein John Efficacy and safety of mipomersen sodium (Kynamro) Expert opinion on drug safety 2013;12 (4):569-579 [PubMed]
  • Motazacker Mohammad Mahdi, Peter Jorge, Treskes Marco, Shoulders Carol C., Kuivenhoven Jan Albert, Hovingh G. Kees Evidence of a polygenic origin of extreme high-density lipoprotein cholesterol levels Arteriosclerosis, thrombosis, and vascular biology 2013;33 (7):1521-1528 [PubMed]
  • Stitziel Nathan O., Fouchier Sigrid W., Sjouke Barbara, Peloso Gina M., Moscoso Alessa M., Auer Paul L., Goel Anuj, Gigante Bruna, Barnes Timothy A., Melander Olle, Orho-Melander Marju, Duga Stefano, Sivapalaratnam Suthesh, Nikpay Majid, Martinelli Nicola, Girelli Domenico, Jackson Rebecca D., Kooperberg Charles, Lange Leslie A., Ardissino Diego, McPherson Ruth, Farrall Martin, Watkins Hugh, Reilly Muredach P., Rader Daniel J., de Faire Ulf, Schunkert Heribert, Erdmann Jeanette, Samani Nilesh J., Charnas Lawrence, Altshuler David, Gabriel Stacey, Kastelein John J. P., Defesche Joep C., Nederveen Aart J., Kathiresan Sekar, Hovingh G. Kees Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia Arteriosclerosis, thrombosis, and vascular biology 2013;33 (12):2909-2914 [PubMed]
  • Nordestgaard Børge G., Chapman M. John, Humphries Steve E., Ginsberg Henry N., Masana Luis, Descamps Olivier S., Wiklund Olov, Hegele Robert A., Raal Frederick J., Defesche Joep C., Wiegman Albert, Santos Raul D., Watts Gerald F., Parhofer Klaus G., Hovingh G. Kees, Kovanen Petri T., Boileau Catherine, Averna Maurizio, Borén Jan, Bruckert Eric, Catapano Alberico L., Kuivenhoven Jan Albert, Pajukanta Päivi, Ray Kausik, Stalenhoef Anton F. H., Stroes Erik, Taskinen Marja-Riitta, Tybjærg-Hansen Anne Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society European heart journal 2013;34 (45):3478-390a [PubMed]
  • Stoekenbroek R. M., van den Bergh Weerman M. A., Hovingh G. K., Potter van Loon B. J., Siegert C. E. H., Holleboom A. G. Familial LCAT deficiency: from renal replacement to enzyme replacement Netherlands journal of medicine 2013;71 (1):29-31 [PubMed]
  • Guo Yiran, Lanktree Matthew B., Taylor Kira C., Hakonarson Hakon, Lange Leslie A., Keating Brendan J., Fairfax Benjamin P., Elbers Clara C., Barnard John, Farrall Martin, Padmanabhan Sandosh, Baumert Jens, Castillo Berta A., Gaunt Tom R., Gong Yan, Rajagopalan Ramakrishnan, Romaine Simon P. R., Kumari Meena, Rafelt Suzanne, Smith Erin N., Li Yun R., Sivapalaratnam Suthesh, van Iperen Erik P. A., Speliotes Elizabeth K., Toskala Elina, Zhang Li, Ochs-Balcom Heather M., Bhangale Tushar R., Chandrupatla Hareesh R., Drenos Fotios, Gieger Christian, Gupta Jayanta, Johnson Toby, Kleber Marcus E., Makino Seiko, Mangino Massimo, Meng Yan, Nelson Christopher P., Pankow James S., Pankratz Nathan, Price Tom S., Shaffer Jonathan, Bezzina Connie R., Chen Wei, de Jong Jonas S., Zafarmand Mohammad H., Zwinderman Aeilko H., Hovingh Kees G., Kastelein John J. P., Trip Mieke D. Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals Human molecular genetics 2013;22 (1):184-201 [PubMed]
  • van Capelleveen Julian C., Bochem Andrea E., Motazacker M. Mahdi, Hovingh G. Kees, Kastelein John J. P. Genetics of HDL-C: a causal link to atherosclerosis? Current atherosclerosis reports 2013;15 (6):326 [PubMed]
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  • Randall Joshua C., Winkler Thomas W., Kutalik Zoltán, Berndt Sonja I., Jackson Anne U., Monda Keri L., Kilpeläinen Tuomas O., Esko Tõnu, Mägi Reedik, Li Shengxu, Workalemahu Tsegaselassie, Feitosa Mary F., Croteau-Chonka Damien C., Day Felix R., Fall Tove, Ferreira Teresa, Gustafsson Stefan, Locke Adam E., Mathieson Iain, Scherag Andre, Vedantam Sailaja, Wood Andrew R., Liang Liming, Steinthorsdottir Valgerdur, Thorleifsson Gudmar, Dermitzakis Emmanouil T., Dimas Antigone S., Karpe Fredrik, Min Josine L., Nicholson George, Clegg Deborah J., Person Thomas, Krohn Jon P., Bauer Sabrina, Buechler Christa, Eisinger Kristina, Bonnefond Amélie, Froguel Philippe, Hottenga Jouke-Jan, Prokopenko Inga, Waite Lindsay L., Harris Tamara B., Smith Albert Vernon, Shuldiner Alan R., McArdle Wendy L., Caulfield Mark J., Munroe Patricia B., Grönberg Henrik, Chen Yii-Der Ida, Li Guo, Beckmann Jacques S., Johnson Toby, Thorsteinsdottir Unnur, Teder-Laving Maris, Khaw Kay-Tee, Wareham Nicholas J., Zhao Jing Hua, Amin Najaf, Oostra Ben A., Kraja Aldi T., Province Michael A., Cupples L. Adrienne, Heard-Costa Nancy L., Kaprio Jaakko, Ripatti Samuli, Surakka Ida, Collins Francis S., Saramies Jouko, Tuomilehto Jaakko, Jula Antti, Salomaa Veikko, Erdmann Jeanette, Hengstenberg Christian, Loley Christina, Schunkert Heribert, Lamina Claudia, Wichmann H. Erich, Albrecht Eva, Gieger Christian, Hicks Andrew A., Johansson Asa, Pramstaller Peter P., Kathiresan Sekar, Speliotes Elizabeth K., Penninx Brenda, Hartikainen Anna-Liisa, Jarvelin Marjo-Riitta, Gyllensten Ulf, Boomsma Dorret I., Campbell Harry, Wilson James F., Chanock Stephen J., Farrall Martin, Goel Anuj, Medina-Gomez Carolina, Rivadeneira Fernando, Estrada Karol, Uitterlinden André G., Hofman Albert, Zillikens M. Carola, den Heijer Martin, Kiemeney Lambertus A., Maschio Andrea, Hall Per, Tyrer Jonathan, Teumer Alexander, Völzke Henry, Kovacs Peter, Tönjes Anke, Mangino Massimo, Spector Tim D., Hayward Caroline, Rudan Igor, Hall Alistair S., Samani Nilesh J., Attwood Antony Paul, Sambrook Jennifer G., Hung Joseph, Palmer Lyle J., Lokki Marja-Liisa, Sinisalo Juha, Boucher Gabrielle, Huikuri Heikki, Lorentzon Mattias, Ohlsson Claes, Eklund Niina, Eriksson Johan G., Barlassina Cristina, Rivolta Carlo, Nolte Ilja M., Snieder Harold, van der Klauw Melanie M., van Vliet-Ostaptchouk Jana V., Gejman Pablo V., Shi Jianxin, Jacobs Kevin B., Wang Zhaoming, Bakker Stephan J. L., Mateo Leach Irene, Navis Gerjan, van der Harst Pim, Martin Nicholas G., Medland Sarah E., Montgomery Grant W., Yang Jian, Chasman Daniel I., Ridker Paul M., Rose Lynda M., Lehtimäki Terho, Raitakari Olli, Absher Devin, Iribarren Carlos, Basart Hanneke, Hovingh Kees G., Hyppönen Elina, Power Chris, Anderson Denise, Beilby John P., Hui Jennie, Jolley Jennifer, Sager Hendrik, Bornstein Stefan R., Schwarz Peter E. H., Kristiansson Kati, Perola Markus, Lindström Jaana, Swift Amy J., Uusitupa Matti, Atalay Mustafa, Lakka Timo A., Rauramaa Rainer, Bolton Jennifer L., Fowkes Gerry, Fraser Ross M., Price Jackie F., Fischer Krista, Krjutå Kov Kaarel, Metspalu Andres, Mihailov Evelin, Langenberg Claudia, Luan Jian'an, Ong Ken K., Chines Peter S., Keinanen-Kiukaanniemi Sirkka M., Saaristo Timo E., Edkins Sarah, Franks Paul W., Hallmans Göran, Shungin Dmitry, Morris Andrew David, Palmer Colin N. A., Erbel Raimund, Moebus Susanne, Nöthen Markus M., Pechlivanis Sonali, Hveem Kristian, Narisu Narisu, Hamsten Anders, Humphries Steve E., Strawbridge Rona J., Tremoli Elena, Grallert Harald, Thorand Barbara, Illig Thomas, Koenig Wolfgang, Müller-Nurasyid Martina, Peters Annette, Boehm Bernhard O., Kleber Marcus E., März Winfried, Winkelmann Bernhard R., Kuusisto Johanna, Laakso Markku, Arveiler Dominique, Cesana Giancarlo, Kuulasmaa Kari, Virtamo Jarmo, Yarnell John W. G., Kuh Diana, Wong Andrew, Lind Lars, de Faire Ulf, Gigante Bruna, Magnusson Patrik K. E., Pedersen Nancy L., Dedoussis George, Dimitriou Maria, Kolovou Genovefa, Kanoni Stavroula, Stirrups Kathleen, Bonnycastle Lori L., Njølstad Inger, Wilsgaard Tom, Ganna Andrea, Rehnberg Emil, Hingorani Aroon, Kivimaki Mika, Kumari Meena, Assimes Themistocles L., Barroso Inês, Boehnke Michael, Borecki Ingrid B., Deloukas Panos, Fox Caroline S., Frayling Timothy, Groop Leif C., Haritunians Talin, Hunter David, Ingelsson Erik, Kaplan Robert, Mohlke Karen L., O'Connell Jeffrey R., Schlessinger David, Strachan David P., Stefansson Kari, van Duijn Cornelia M., Abecasis Gonçalo R., McCarthy Mark I., Hirschhorn Joel N., Qi Lu, Loos Ruth J. F., Lindgren Cecilia M., North Kari E., Heid Iris M. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits PLoS genetics 2013;9 (6):e1003500 [PubMed]
  • Besseling J., Hutten B. A., Meijers J. C. M., Trip M. D., Hovingh G. K. Statin therapy and levels of hemostatic factors in a healthy population: the Multi-Ethnic Study of Atherosclerosis: a rebuttal Journal of thrombosis and haemostasis 2013;11 (9):1787-1788 [PubMed]
  • Singaraja Roshni R., Sivapalaratnam Suthesh, Hovingh Kees, Dubé Marie-Pierre, Castro-Perez José, Collins Heidi L., Adelman Steven J., Riwanto Meliana, Manz Jasmin, Hubbard Brian, Tietjen Ian, Wong Kenny, Mitnaul Lyndon J., van Heek Margaret, Lin Linus, Roddy Thomas A., McEwen Jason, Dallinge-Thie Geesje, van Vark-van der Zee Leonie, Verwoert Germaine, Winther Michael, van Duijn Cornelia, Hofman Albert, Trip Mieke D., Marais A. David, Asztalos Bela, Landmesser Ulf, Sijbrands Eric, Kastelein John J., Hayden Michael R. The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans Circulation. Cardiovascular genetics 2013;6 (1):54-62 [PubMed]

2012

  • Motazacker Mohammad Mahdi, Pirruccello James, Huijgen Roeland, Do Ron, Gabriel Stacey, Peter Jorge, Kuivenhoven Jan Albert, Defesche Joep C., Kastelein John J. P., Hovingh G. Kees, Zelcer Noam, Kathiresan Sekar, Fouchier Sigrid W. Advances in genetics show the need for extending screening strategies for autosomal dominant hypercholesterolaemia European heart journal 2012;33 (11):1360-1366 [PubMed]
  • Brunham L. R., Lansberg P. J., Zhang L., Miao F., Carter C., Hovingh G. K., Visscher H., Jukema J. W., Stalenhoef A. F., Ross C. J. D., Carleton B. C., Kastelein J. J. P., Hayden M. R. Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin pharmacogenomics journal 2012;12 (3):233-237 [PubMed]
  • Huijgen Roeland, Sjouke Barbara, Vis Kelly, de Randamie Janine S. E., Defesche Joep C., Kastelein John J. P., Hovingh G. Kees, Fouchier Sigrid W. Genetic Variation in APOB, PCSK9, and ANGPTL3 in Carriers of Pathogenic Autosomal Dominant Hypercholesterolemic Mutations with Unexpected Low LDL-C Levels Human mutation 2012;33 (2):448-455 [PubMed]
  • Chantepie Sandrine, Bochem Andrea E., Chapman M. John, Hovingh G. Kees, Kontush Anatol High-Density Lipoprotein (HDL) Particle Subpopulations in Heterozygous Cholesteryl Ester Transfer Protein (CETP) Deficiency: Maintenance of Antioxidative Activity PLoS ONE 2012;7 (11):e49336 [PubMed]
  • Tietjen Ian, Hovingh G. Kees, Singaraja Roshni, Radomski Chris, McEwen Jason, Chan Elden, Mattice Maryanne, Legendre Annick, Kastelein John J. P., Hayden Michael R. Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2012;1821 (3):416-424 [PubMed]
  • Scott Robert A., Lagou Vasiliki, Welch Ryan P., Wheeler Eleanor, Montasser May E., Luan Jian'an, Mägi Reedik, Strawbridge Rona J., Rehnberg Emil, Gustafsson Stefan, Kanoni Stavroula, Rasmussen-Torvik Laura J., Yengo Loïc, Lecoeur Cecile, Shungin Dmitry, Sanna Serena, Sidore Carlo, Johnson Paul C. D., Jukema J. Wouter, Johnson Toby, Mahajan Anubha, Verweij Niek, Thorleifsson Gudmar, Hottenga Jouke-Jan, Shah Sonia, Smith Albert V., Sennblad Bengt, Gieger Christian, Salo Perttu, Perola Markus, Timpson Nicholas J., Evans David M., Pourcain Beate St, Wu Ying, Andrews Jeanette S., Hui Jennie, Bielak Lawrence F., Zhao Wei, Horikoshi Momoko, Navarro Pau, Isaacs Aaron, O'Connell Jeffrey R., Stirrups Kathleen, Vitart Veronique, Hayward Caroline, Esko Tõnu, Mihailov Evelin, Fraser Ross M., Fall Tove, Voight Benjamin F., Raychaudhuri Soumya, Chen Han, Lindgren Cecilia M., Morris Andrew P., Rayner Nigel W., Robertson Neil, Rybin Denis, Liu Ching-Ti, Beckmann Jacques S., Willems Sara M., Chines Peter S., Jackson Anne U., Kang Hyun Min, Stringham Heather M., Song Kijoung, Tanaka Toshiko, Peden John F., Goel Anuj, Hicks Andrew A., An Ping, Müller-Nurasyid Martina, Franco-Cereceda Anders, Folkersen Lasse, Marullo Letizia, Jansen Hanneke, Oldehinkel Albertine J., Bruinenberg Marcel, Pankow James S., North Kari E., Forouhi Nita G., Loos Ruth J. F., Edkins Sarah, Varga Tibor V., Hallmans Göran, Oksa Heikki, Antonella Mulas, Nagaraja Ramaiah, Trompet Stella, Ford Ian, Bakker Stephan J. L., Kong Augustine, Kumari Meena, Gigante Bruna, Herder Christian, Munroe Patricia B., Caulfield Mark, Antti Jula, Mangino Massimo, Small Kerrin, Miljkovic Iva, Liu Yongmei, Atalay Mustafa, Kiess Wieland, James Alan L., Rivadeneira Fernando, Uitterlinden Andre G., Palmer Colin N. A., Doney Alex S. F., Willemsen Gonneke, Smit Johannes H., Campbell Susan, Polasek Ozren, Bonnycastle Lori L., Hercberg Serge, Dimitriou Maria, Bolton Jennifer L., Fowkes Gerard R., Kovacs Peter, Lindström Jaana, Zemunik Tatijana, Bandinelli Stefania, Wild Sarah H., Basart Hanneke V., Rathmann Wolfgang, Grallert Harald, Maerz Winfried, Kleber Marcus E., Boehm Bernhard O., Peters Annette, Pramstaller Peter P., Province Michael A., Borecki Ingrid B., Hastie Nicholas D., Rudan Igor, Campbell Harry, Watkins Hugh, Farrall Martin, Stumvoll Michael, Ferrucci Luigi, Waterworth Dawn M., Bergman Richard N., Collins Francis S., Tuomilehto Jaakko, Watanabe Richard M., de Geus Eco J. C., Penninx Brenda W., Hofman Albert, Oostra Ben A., Psaty Bruce M., Vollenweider Peter, Wilson James F., Wright Alan F., Hovingh G. Kees, Metspalu Andres, Uusitupa Matti, Magnusson Patrik K. E., Kyvik Kirsten O., Kaprio Jaakko, Price Jackie F., Dedoussis George V., Deloukas Panos, Meneton Pierre, Lind Lars, Boehnke Michael, Shuldiner Alan R., van Duijn Cornelia M., Morris Andrew D., Toenjes Anke, Peyser Patricia A., Beilby John P., Körner Antje, Kuusisto Johanna, Laakso Markku, Bornstein Stefan R., Schwarz Peter E. H., Lakka Timo A., Rauramaa Rainer, Adair Linda S., Smith George Davey, Spector Tim D., Illig Thomas, de Faire Ulf, Hamsten Anders, Gudnason Vilmundur, Kivimaki Mika, Hingorani Aroon, Keinanen-Kiukaanniemi Sirkka M., Saaristo Timo E., Boomsma Dorret I., Stefansson Kari, van der Harst Pim, Dupuis Josée, Pedersen Nancy L., Sattar Naveed, Harris Tamara B., Cucca Francesco, Ripatti Samuli, Salomaa Veikko, Mohlke Karen L., Balkau Beverley, Froguel Philippe, Pouta Anneli, Jarvelin Marjo-Riitta, Wareham Nicholas J., Bouatia-Naji Nabila, McCarthy Mark I., Franks Paul W., Meigs James B., Teslovich Tanya M., Florez Jose C., Langenberg Claudia, Ingelsson Erik, Prokopenko Inga, Barroso Inês Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways Nature genetics 2012;44 (9):991-+ [PubMed]
  • Morris Andrew P., Voight Benjamin F., Teslovich Tanya M., Ferreira Teresa, Segrè Ayellet V., Steinthorsdottir Valgerdur, Strawbridge Rona J., Khan Hassan, Grallert Harald, Mahajan Anubha, Prokopenko Inga, Kang Hyun Min, Dina Christian, Esko Tonu, Fraser Ross M., Kanoni Stavroula, Kumar Ashish, Lagou Vasiliki, Langenberg Claudia, Luan Jian'an, Lindgren Cecilia M., Müller-Nurasyid Martina, Pechlivanis Sonali, Rayner N. William, Scott Laura J., Wiltshire Steven, Yengo Loic, Kinnunen Leena, Rossin Elizabeth J., Raychaudhuri Soumya, Johnson Andrew D., Dimas Antigone S., Loos Ruth J. F., Vedantam Sailaja, Chen Han, Florez Jose C., Fox Caroline, Liu Ching-Ti, Rybin Denis, Couper David J., Kao Wen Hong L., Li Man, Cornelis Marilyn C., Kraft Peter, Sun Qi, van Dam Rob M., Stringham Heather M., Chines Peter S., Fischer Krista, Fontanillas Pierre, Holmen Oddgeir L., Hunt Sarah E., Jackson Anne U., Kong Augustine, Lawrence Robert, Meyer Julia, Perry John R. B., Platou Carl G. P., Potter Simon, Rehnberg Emil, Robertson Neil, Sivapalaratnam Suthesh, Stančáková Alena, Stirrups Kathleen, Thorleifsson Gudmar, Tikkanen Emmi, Wood Andrew R., Almgren Peter, Atalay Mustafa, Benediktsson Rafn, Bonnycastle Lori L., Burtt Noël, Carey Jason, Charpentier Guillaume, Crenshaw Andrew T., Doney Alex S. F., Dorkhan Mozhgan, Edkins Sarah, Emilsson Valur, Eury Elodie, Forsen Tom, Gertow Karl, Gigante Bruna, Grant George B., Groves Christopher J., Guiducci Candace, Herder Christian, Hreidarsson Astradur B., Hui Jennie, James Alan, Jonsson Anna, Rathmann Wolfgang, Klopp Norman, Kravic Jasmina, Krjutškov Kaarel, Langford Cordelia, Leander Karin, Lindholm Eero, Lobbens Stéphane, Männistö Satu, Mirza Ghazala, Mühleisen Thomas W., Musk Bill, Parkin Melissa, Rallidis Loukianos, Saramies Jouko, Sennblad Bengt, Shah Sonia, Sigurðsson Gunnar, Silveira Angela, Steinbach Gerald, Thorand Barbara, Trakalo Joseph, Veglia Fabrizio, Wennauer Roman, Winckler Wendy, Zabaneh Delilah, Campbell Harry, van Duijn Cornelia, Uitterlinden Andre G., Hofman Albert, Sijbrands Eric, Abecasis Goncalo R., Owen Katharine R., Zeggini Eleftheria, Trip Mieke D., Forouhi Nita G., Syvänen Ann-Christine, Eriksson Johan G., Peltonen Leena, Nöthen Markus M., Balkau Beverley, Palmer Colin N. A., Lyssenko Valeriya, Tuomi Tiinamaija, Isomaa Bo, Hunter David J., Qi Lu, Shuldiner Alan R., Roden Michael, Barroso Ines, Wilsgaard Tom, Beilby John, Hovingh Kees, Price Jackie F., Wilson James F., Rauramaa Rainer, Lakka Timo A., Lind Lars, Dedoussis George, Njølstad Inger, Pedersen Nancy L., Khaw Kay-Tee, Wareham Nicholas J., Keinanen-Kiukaanniemi Sirkka M., Saaristo Timo E., Korpi-Hyövälti Eeva, Saltevo Juha, Laakso Markku, Kuusisto Johanna, Metspalu Andres, Collins Francis S., Mohlke Karen L., Bergman Richard N., Tuomilehto Jaakko, Boehm Bernhard O., Gieger Christian, Hveem Kristian, Cauchi Stephane, Froguel Philippe, Baldassarre Damiano, Tremoli Elena, Humphries Steve E., Saleheen Danish, Danesh John, Ingelsson Erik, Ripatti Samuli, Salomaa Veikko, Erbel Raimund, Jöckel Karl-Heinz, Moebus Susanne, Peters Annette, Illig Thomas, de Faire Ulf, Hamsten Anders, Morris Andrew D., Donnelly Peter J., Frayling Timothy M., Hattersley Andrew T., Boerwinkle Eric, Melander Olle, Kathiresan Sekar, Nilsson Peter M., Deloukas Panos, Thorsteinsdottir Unnur, Groop Leif C., Stefansson Kari, Hu Frank, Pankow James S., Dupuis Josée, Meigs James B., Altshuler David, Boehnke Michael, McCarthy Mark I. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Nature genetics 2012;44 (9):981-+ [PubMed]
  • Asselbergs Folkert W., Guo Yiran, van Iperen Erik P. A., Sivapalaratnam Suthesh, Tragante Vinicius, Lanktree Matthew B., Lange Leslie A., Almoguera Berta, Appelman Yolande E., Barnard John, Baumert Jens, Beitelshees Amber L., Bhangale Tushar R., Chen Yii-Der Ida, Gaunt Tom R., Gong Yan, Hopewell Jemma C., Johnson Toby, Kleber Marcus E., Langaee Taimour Y., Li Mingyao, Li Yun R., Liu Kiang, McDonough Caitrin W., Meijs Matthijs F. L., Middelberg Rita P. S., Musunuru Kiran, Nelson Christopher P., O'Connell Jeffery R., Padmanabhan Sandosh, Pankow James S., Pankratz Nathan, Rafelt Suzanne, Rajagopalan Ramakrishnan, Romaine Simon P. R., Schork Nicholas J., Shaffer Jonathan, Shen Haiqing, Smith Erin N., Tischfield Sam E., van der Most Peter J., van Vliet-Ostaptchouk Jana V., Verweij Niek, Chen Wei, Zwinderman A. H., Bezzina Connie R., Trip Mieke D., Wilde Arthur A. M., Hovingh G. Kees, Kastelein John J. P. Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci American journal of human genetics 2012;91 (5):823-838 [PubMed]
  • Holleboom Adriaan G., Daniil Georgios, Fu Xiaoming, Zhang Renliang, Hovingh G. Kees, Schimmel Alinda W., Kastelein John J. P., Stroes Erik S. G., Witztum Joseph L., Hutten Barbara A., Tsimikas Sotirios, Hazen Stanley L., Chroni Angeliki, Kuivenhoven Jan Albert Lipid Oxidation in Carriers of Lecithin: Cholesterol Acyltransferase Gene Mutations Arteriosclerosis, thrombosis, and vascular biology 2012;32 (12):3066-+ [PubMed]
  • Gurdasani Deepti, Sjouke Barbara, Tsimikas Sotirios, Hovingh G. Kees, Luben Robert N., Wainwright Nicholas W. J., Pomilla Cristina, Wareham Nicholas J., Khaw Kay-Tee, Boekholdt S. Matthijs, Sandhu Manjinder S. Lipoprotein(a) and Risk of Coronary, Cerebrovascular, and Peripheral Artery Disease The EPIC-Norfolk Prospective Population Study Arteriosclerosis, thrombosis, and vascular biology 2012;32 (12):3058-3065 [PubMed]
  • Sivapalaratnam Suthesh, Basart Hanneke, Watkins Nicholas A., Maiwald Stepanie, Rendon Augusto, Krishnan Unni, Sondermeijer Brigitte M., Creemers Esther E., Pinto-Sietsma Sara J., Hovingh Kees, Ouwehand Willem H., Kastelein John J. P., Goodall Alison H., Trip Mieke D. Monocyte Gene Expression Signature of Patients with Early Onset Coronary Artery Disease PLoS ONE 2012;7 (2):e32166 [PubMed]
  • Dastani Zari, Hivert Marie-France, Timpson Nicholas, Perry John R. B., Yuan Xin, Scott Robert A., Henneman Peter, Heid Iris M., Kizer Jorge R., Lyytikäinen Leo-Pekka, Fuchsberger Christian, Tanaka Toshiko, Morris Andrew P., Small Kerrin, Isaacs Aaron, Beekman Marian, Coassin Stefan, Lohman Kurt, Qi Lu, Kanoni Stavroula, Pankow James S., Uh Hae-Won, Wu Ying, Bidulescu Aurelian, Rasmussen-Torvik Laura J., Greenwood Celia M. T., Ladouceur Martin, Grimsby Jonna, Manning Alisa K., Liu Ching-Ti, Kooner Jaspal, Mooser Vincent E., Vollenweider Peter, Kapur Karen A., Chambers John, Wareham Nicholas J., Langenberg Claudia, Frants Rune, Willems-Vandijk Ko, Oostra Ben A., Willems Sara M., Lamina Claudia, Winkler Thomas W., Psaty Bruce M., Tracy Russell P., Brody Jennifer, Fouchier Sigrid W., Hovingh G. Kees, Boekholdt S. Matthijs, Kastelein John J. P. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals PLoS genetics 2012;8 (3):e1002607 [PubMed]
  • van den Bogaard Bas, Holleboom Adriaan G., Duivenvoorden Raphaël, Hutten Barbara A., Kastelein John J. P., Hovingh G. Kees, Kuivenhoven Jan Albert, Stroes Erik S. G., van den Born Bert-Jan H. Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness Atherosclerosis 2012;225 (2):481-485 [PubMed]
  • Tietjen Ian, Hovingh G. Kees, Singaraja Roshni R., Radomski Chris, Barhdadi Amina, McEwen Jason, Chan Elden, Mattice Maryanne, Legendre Annick, Franchini Patrick L., Dubé Marie-Pierre, Kastelein John J. P., Hayden Michael R. Segregation of LIPG, CETP, and GALNT2 Mutations in Caucasian Families with Extremely High HDL Cholesterol PLoS ONE 2012;7 (8):e37437 [PubMed]
  • Arsenault Benoit J., Boekholdt S. Matthijs, Hovingh G. Kees, Hyde Craig L., Demicco David A., Chatterjee Aurobindo, Barter Philip, Deedwania Prakash, Waters David D., LaRosa John C., Pedersen Terje R., Kastelein John J. P. The 719Arg Variant of KIF6 and Cardiovascular Outcomes in Statin-Treated, Stable Coronary Patients of the Treating to New Targets and Incremental Decrease in End Points Through Aggressive Lipid-Lowering Prospective Studies Circulation. Cardiovascular genetics 2012;5 (1):51-57 [PubMed]
  • van Zwieten Rob, Bochem Andrea E., Hilarius Petra M., van Bruggen Robin, Bergkamp Ferry, Hovingh G. Kees, Verhoeven Arthur J. The cholesterol content of the erythrocyte membrane is an important determinant of phosphatidylserine exposure BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2012;1821 (12):1493-1500 [PubMed]
  • Sivapalaratnam Suthesh The molecular basis of early onset cardiovascular disease 2012. 276p. ISBN 9789461083326. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Levi M. M., Kastelein J. J. P.; Co-supervisors: Trip M. D., Ouwehand W. H., Hovingh G. K.)
  • Lambert Gilles, Sjouke Barbara, Choque Benjamin, Kastelein John J. P., Hovingh G. Kees The PCSK9 decade Journal of lipid research 2012;53 (12):2515-2524 [PubMed]

2011

  • Duivenvoorden Raphaël, Holleboom Adriaan G., van den Bogaard Bas, Nederveen Aart J., de Groot Eric, Hutten Barbara A., Schimmel Alinda W., Hovingh G. Kees, Kastelein John J. P., Kuivenhoven Jan Albert, Stroes Erik S. G. Cholesterol Acyltransferase Gene Mutations Have Accelerated Atherogenesis as Assessed by Carotid 3.0-T Magnetic Resonance Imaging Carriers of Lecithin Journal of the American College of Cardiology 2011;58 (24):2481-2487 [PubMed]
  • Sjouke B., Kusters D. M., Kastelein J. J. P., Hovingh G. K. Familial hypercholesterolemia: present and future management Current cardiology reports 2011;13 (6):527-536 [PubMed]
  • Holleboom Adriaan G. Genetic disorders of HDL metabolism: from model to mechanism 2011. 422p. ISBN 9789461081735. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Stroes E. S. G., Kastelein J. J. P.; Co-supervisors: Kuivenhoven J. A., Hovingh G. K.)
  • Vergeer Menno, Korporaal Suzanne J. A., Franssen Remco, Meurs Illiana, Out Ruud, Hovingh G. Kees, Hoekstra Menno, Sierts Jeroen A., Dallinga-Thie Geesje M., Motazacker Mohammad Mahdi, Holleboom Adriaan G., van Berkel Theo J. C., Kastelein John J. P., van Eck Miranda, Kuivenhoven Jan Albert Genetic Variant of the Scavenger Receptor BI in Humans New England journal of medicine 2011;364 (2):136-145 [PubMed]
  • Sivapalaratnam S., Motazacker M. M., Maiwald S., Hovingh G. K., Kastelein J. J. P., Levi M. [=Marcel M.], Trip M. D., Dallinga-Thie G. M. Genome-wide association studies in atherosclerosis Current atherosclerosis reports 2011;13 (3):225-232 [PubMed]
  • Chambers John C., Zhang Weihua, Sehmi Joban, Li Xinzhong, Wass Mark N., van der Harst Pim, Holm Hilma, Sanna Serena, Kavousi Maryam, Baumeister Sebastian E., Coin Lachlan J., Deng Guohong, Gieger Christian, Heard-Costa Nancy L., Hottenga Jouke-Jan, Kühnel Brigitte, Kumar Vinod, Lagou Vasiliki, Liang Liming, Luan Jian'an, Vidal Pedro Marques, Mateo Leach Irene, O'Reilly Paul F., Peden John F., Rahmioglu Nilufer, Soininen Pasi, Speliotes Elizabeth K., Yuan Xin, Thorleifsson Gudmar, Alizadeh Behrooz Z., Atwood Larry D., Borecki Ingrid B., Brown Morris J., Charoen Pimphen, Cucca Francesco, Das Debashish, de Geus Eco J. C., Dixon Anna L., Döring Angela, Ehret Georg, Eyjolfsson Gudmundur I., Farrall Martin, Forouhi Nita G., Friedrich Nele, Yang J., Fouchier S. W., Hovingh G. Kees, Boekholdt S. M., Kastelein J. J., Henneman P. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma Nature genetics 2011;43 (11):1131-U129 [PubMed]
  • Holleboom Adriaan G., Karlsson Helen, Lin Ruei-Shiuan, Beres Thomas M., Sierts Jeroen A., Herman Daniel S., Stroes Erik S. G., Aerts Johannes M., Kastelein John J. P., Motazacker Mohammad M., Dallinga-Thie Geesje M., Levels Johannes H. M., Zwinderman Aeilko H., Seidman Jonathan G., Seidman Christine E., Ljunggren Stefan, Lefeber Dirk J., Morava Eva, Wevers Ron A., Fritz Timothy A., Tabak Lawrence A., Lindahl Mats, Hovingh G. Kees, Kuivenhoven Jan Albert Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man Cell metabolism 2011;14 (6):811-818 [PubMed]
  • Holleboom Adriaan G., Kuivenhoven Jan A., Peelman Frank, Schimmel Alinda W., Peter Jorge, Defesche Joep C., Kastelein John J. P., Hovingh G. Kees, Stroes Erik S., Motazacker Mohammad Mahdi High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in The Netherlands: identification and characterization of eight novel mutations Human mutation 2011;32 (11):1290-1298 [PubMed]
  • Brunham Liam R., Tietjen Ian, Bochem Andrea E., Singaraja Roshni R., Franchini Patrick L., Radomski Chris, Mattice Maryanne, Legendre Annick, Hovingh G. Kees, Kastelein John J. P., Hayden Michael R. Novel mutations in scavenger receptor BI associated with high HDL cholesterol in humans Clinical genetics 2011;79 (6):575-581 [PubMed]
  • Holleboom A. G., Kuivenhoven J. A., van Olden C. C., Peter J., Schimmel A. W., Levels J. H., Valentijn R. M., Vos P., Defesche J. C., Kastelein J. J. P., Hovingh G. K., Stroes E. S. G., Hollak C. E. M. Proteinuria in early childhood due to familial LCAT deficiency caused by loss of a disulfide bond in lecithin:cholesterol acyl transferase Atherosclerosis 2011;216 (1):161-165 [PubMed]

2010

  • Hovingh G. K., Bochem Andrea E., Kastelein John J. P. Apolipoprotein A-I mimetic peptides Current opinion in lipidology 2010;21 (6):481-486 [PubMed]
  • Teslovich Tanya M., Musunuru Kiran, Smith Albert V., Edmondson Andrew C., Stylianou Ioannis M., Koseki Masahiro, Pirruccello James P., Ripatti Samuli, Chasman Daniel I., Willer Cristen J., Johansen Christopher T., Fouchier Sigrid W., Isaacs Aaron, Peloso Gina M., Barbalic Maja, Ricketts Sally L., Bis Joshua C., Aulchenko Yurii S., Thorleifsson Gudmar, Feitosa Mary F., Chambers John, Orho-Melander Marju, Melander Olle, Johnson Toby, Li Xiaohui, Guo Xiuqing, Li Mingyao, Shin Cho Yoon, Jin Go Min, Jin Kim Young, Lee Jong-Young, Park Taesung, Kim Kyunga, Sim Xueling, Twee-Hee Ong Rick, Croteau-Chonka Damien C., Lange Leslie A., Smith Joshua D., Song Kijoung, Hua Zhao Jing, Yuan Xin, Luan Jian'an, Lamina Claudia, Ziegler Andreas, Zhang Weihua, Zee Robert Y. L., Wright Alan F., Witteman Jacqueline C. M., Wilson James F., Willemsen Gonneke, Wichmann H.-Erich, Whitfield John B., Waterworth Dawn M., Wareham Nicholas J., Waeber Gérard, Vollenweider Peter, Voight Benjamin F., Vitart Veronique, Uitterlinden Andre G., Uda Manuela, Tuomilehto Jaakko, Thompson John R., Tanaka Toshiko, Surakka Ida, Stringham Heather M., Spector Tim D., Soranzo Nicole, Smit Johannes H., Sinisalo Juha, Silander Kaisa, Sijbrands Eric J. G., Scuteri Angelo, Scott James, Schlessinger David, Sanna Serena, Salomaa Veikko, Saharinen Juha, Sabatti Chiara, Ruokonen Aimo, Rudan Igor, Rose Lynda M., Roberts Robert, Rieder Mark, Psaty Bruce M., Pramstaller Peter P., Pichler Irene, Perola Markus, Penninx Brenda W. J. H., Pedersen Nancy L., Pattaro Cristian, Parker Alex N., Pare Guillaume, Oostra Ben A., O'Donnell Christopher J., Nieminen Markku S., Nickerson Deborah A., Montgomery Grant W., Meitinger Thomas, McPherson Ruth, McCarthy Mark I., McArdle Wendy, Masson David, Martin Nicholas G., Marroni Fabio, Mangino Massimo, Magnusson Patrik K. E., Lucas Gavin, Luben Robert, Loos Ruth J. F., Lokki Marja-Liisa, Lettre Guillaume, Langenberg Claudia, Launer Lenore J., Lakatta Edward G., Laaksonen Reijo, Kyvik Kirsten O., Kronenberg Florian, König Inke R., Khaw Kay-Tee, Kaprio Jaakko, Kaplan Lee M., Johansson Asa, Jarvelin Marjo-Riitta, Janssens A. Cecile J. W., Ingelsson Erik, Igl Wilmar, Hovingh G. Kees, Hottenga Jouke-Jan, Hofman Albert, Hicks Andrew A., Hengstenberg Christian, Heid Iris M., Hayward Caroline, Havulinna Aki S., Hastie Nicholas D., Harris Tamara B., Haritunians Talin, Hall Alistair S., Gyllensten Ulf, Guiducci Candace, Groop Leif C., Gonzalez Elena, Gieger Christian, Freimer Nelson B., Ferrucci Luigi, Erdmann Jeanette, Elliott Paul, Ejebe Kenechi G., Döring Angela, Dominiczak Anna F., Demissie Serkalem, Deloukas Panagiotis, de Geus Eco J. C., de Faire Ulf, Crawford Gabriel, Collins Francis S., Chen Yii-der I., Caulfield Mark J., Campbell Harry, Burtt Noel P., Bonnycastle Lori L., Boomsma Dorret I., Boekholdt S. Matthijs, Bergman Richard N., Barroso Inês, Bandinelli Stefania, Ballantyne Christie M., Assimes Themistocles L., Quertermous Thomas, Altshuler David, Seielstad Mark, Wong Tien Y., Tai E.-Shyong, Feranil Alan B., Kuzawa Christopher W., Adair Linda S., Taylor Herman A., Borecki Ingrid B., Gabriel Stacey B., Wilson James G., Holm Hilma, Thorsteinsdottir Unnur, Gudnason Vilmundur, Krauss Ronald M., Mohlke Karen L., Ordovas Jose M., Munroe Patricia B., Kooner Jaspal S., Tall Alan R., Hegele Robert A., Kastelein John J. P., Schadt Eric E., Rotter Jerome I., Boerwinkle Eric, Strachan David P., Mooser Vincent, Stefansson Kari, Reilly Muredach P., Samani Nilesh J., Schunkert Heribert, Cupples L. Adrienne, Sandhu Manjinder S., Ridker Paul M., Rader Daniel J., van Duijn Cornelia M., Peltonen Leena, Abecasis Gonçalo R., Boehnke Michael, Kathiresan Sekar Biological, clinical and population relevance of 95 loci for blood lipids Nature 2010;466 (7307):707-713 [PubMed]
  • Candini C., Schimmel A. W., Peter J., Bochem A. E., Holleboom A. G., Vergeer M., Dullaart R. P. F., Dallinga-Thie G. M., Hovingh G. K., Khoo K. L., Fasano T., Bocchi L., Calandra S., Kuivenhoven J. A., Motazacker M. M. Identification and characterization of novel loss of function mutations in ATP-binding cassette transporter A1 in patients with low plasma high-density lipoprotein cholesterol Atherosclerosis 2010;213 (2):492-498 [PubMed]
  • Holleboom A. G., Kuivenhoven J. A., Vergeer M., Hovingh G. K., van Miert J. N., Wareham N. J., Kastelein J. J. P., Khaw K.-T., Boekholdt S. M. Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study Journal of lipid research 2010;51 (2):416-421 [PubMed]

2009

  • Thompson John F., Hyde Craig L., Wood Linda S., Paciga Sara A., Hinds David A., Cox David R., Hovingh G. Kees, Kastelein John J. P. Comprehensive Whole-Genome and Candidate Gene Analysis for Response to Statin Therapy in the Treating to New Targets (TNT) Cohort Circulation. Cardiovascular genetics 2009;2 (2):173-U240 [PubMed]
  • Herman Daniel S., Hovingh G. Kees, Iartchouk Oleg, Rehm Heidi L., Kucherlapati Raju, Seidman J. G., Seidman Christine E. Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection Nature methods 2009;6 (7):507-510 [PubMed]
  • El Harchaoui Karim, Arsenault Benoit J., Franssen Remco, Després Jean-Pierre, Hovingh G. Kees, Stroes Erik S. G., Otvos James D., Wareham Nicholas J., Kastelein John J. P., Khaw Kay-Tee, Boekholdt S. Matthijs High-Density Lipoprotein Particle Size and Concentration and Coronary Risk Annals of internal medicine 2009;150 (2):84-U43 [PubMed]
  • Harchaoui Karim El, Franssen Remco, Hovingh G. Kees, Bisoendial Radjesh J., Stellaard Frans, Kuipers Folkert, Kastelein John J. P., Kuivenhoven Jan Albert, Stroes Erik S. G., Groen Albert K. Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia Atherosclerosis 2009;207 (2):614-616 [PubMed]
  • Strang Aart C., Hovingh G. Kees, Stroes Erik S. G., Kastelein John J. P. The genetics of high-density lipoprotein metabolism: clinical relevance for therapeutic approaches American journal of cardiology 2009;104 (10 Suppl):22E-31E [PubMed]

2008

  • Levi Marcel, Hovingh Kees Bleeding complications in patients on anticoagulants who would have been disqualified for clinical trials Thrombosis and haemostasis 2008;100 (6):1047-1051 [PubMed]
  • Levi Marcel, Hovingh G. Kees, Cannegieter Suzanne C., Vermeulen Marinus, Büller Harry R., Rosendaal Frits R. Bleeding in patients receiving vitamin K antagonists who would have been excluded from trials on which the indication for anticoagulation was based Blood 2008;111 (9):4471-4476 [PubMed]
  • Birjmohun Rakesh S., Hovingh G. Kees, Stroes Erik S. G., Hofstra Jorit J., Dallinga-Thie Geesje M., Meijers Joost C. M., Kastelein John J. P., Levi Marcel Effects of short-term and long-term danazol treatment on lipoproteins, coagulation, and progression of atherosclerosis: two clinical trials in healthy volunteers and patients with hereditary angioedema Clinical therapeutics 2008;30 (12):2314-2323 [PubMed]
  • Holleboom Adriaan G., Vergeer Menno, Hovingh G. Kees, Kastelein John Jp, Kuivenhoven Jan Albert The value of HDL genetics Current opinion in lipidology 2008;19 (4):385-394 [PubMed]

2007

  • van der Steeg Wim A., Hovingh G. Kees, Klerkx Anke H. E. M., Hutten Barbara A., Nootenboom Inge C., Levels Johannes H. M., van Tol Arie, Dallinga-Thie Gees M., Zwinderman Aeilko H., Kastelein John J. P., Kuivenhoven Jan Albert Cholesteryl ester transfer protein and hyperalphalipoproteinemia in Caucasians Journal of lipid research 2007;48 (3):674-682 [PubMed]
  • Hovingh G. K., Jaarsma W. Dyspneuin: G. K. Hovingh, G. A. Somsen, editors. Probleemgeoriënteerd denken in de cardiologie en vasculaire geneeskunde; een praktijkboek voor de opleiding en de kliniek. Utrecht: De Tijdstroom; 2007. p. 283-294, ISBN 9789058981080
  • van Leuven Sander I., Hezemans Rachel, Levels Johannes H., Snoek Susan, Stokkers Pieter C., Hovingh G. Kees, Kastelein John J. P., Stroes Erik S., de Groot Eric, Hommes Daan W. Enhanced atherogenesis and altered high density lipoprotein in patients with Crohn's disease Journal of lipid research 2007;48 (12):2640-2646 [PubMed]
  • Hovingh G. K., Somsen G. A. Probleemgeoriënteerd denken in de cardiologie en vasculaire geneeskunde; een praktijkboek voor de opleiding en de kliniekUtrecht: De Tijdstroom; 2007. ISBN 9789058981080 (Probleemgeoriënteerd denken in de Interne Geneeskunde)
  • Hovingh G. K., Knuistingh Neven A. Vasculair DidactAlphen aan de Rijn: Van Zuiden Communications; 2007.

2006

  • Boekholdt S. M., Souverein O. W., Tanck M. W. T., Hovingh G. K., Kuivenhoven J. A., Peters R. I. G., Jansen H., Schiffers P. M. H., van der Wall E. E., Doevendans P. A., Reitsma P. H., Zwinderman A. H., Kastelein J. J. P., Jukema J. W. Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels Clinical genetics 2006;69 (3):263-270 [PubMed]

2005

  • Hovingh G. Kees, Hutten Barbara A., Holleboom Adriaan G., Petersen Wilma, Rol Patrick, Stalenhoef Anton, Zwinderman Aeilko H., de Groot Eric, Kastelein John J. P., Kuivenhoven Jan Albert Compromised LCAT function is associated with increased atherosclerosis Circulation 2005;112 (6):879-884 [PubMed]
  • Bisoendial Radjesh J., Hovingh G. Kees, El Harchaoui Karim, Levels Johannes H. M., Tsimikas Sotirios, Pu Kewei, Zwinderman Aeilko E., Kuivenhoven Jan Albert, Kastelein John J. P., Stroes Erik S. G. Consequences of cholesteryl ester transfer protein inhibition in patients with familial hypoalphalipoproteinemia Arteriosclerosis, thrombosis, and vascular biology 2005;25 (9):E133-E134 [PubMed]
  • de Groot E., Hovingh G. K., Zwinderman A. H., Wiegman A., Smit A. J., Kastelein J. J. P. Data density curves of B-mode ultrasound arterial wall thickness measurements in unaffected control and at-risk populations International angiology 2005;24 (4):359-365 [PubMed]
  • Hovingh G. Kees, de Groot Eric, van der Steeg Wim, Boekholdt S. Matthijs, Hutten Barbara A., Kuivenhoven Jan Albert, Kastelein John J. P. Inherited disorders of HDL metabolism and atherosclerosis Current opinion in lipidology 2005;16 (2):139-145 [PubMed]
  • Hovingh G. K. Molecular defects in the metabolism of the HDL particle and the consequences for atherosclerosis progression 2005. 251p. ISBN 9789090192444. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kastelein J. J. P.; Co-supervisors: Groen A. K., Kuivenhoven J. A.)

2004

  • Hovingh G. Kees, Brownlie Alison, Bisoendial Radjesh J., Dube Marie Pierre, Levels Johannes H. M., Petersen Wilma, Dullaart Robin P. F., Stroes Erik S. G., Zwinderman Aeilko H., de Groot Eric, Hayden Michael R., Kuivenhoven Jan Albert, Kastelein John J. P. A novel ApoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease Journal of the American College of Cardiology 2004;44 (7):1429-1435 [PubMed]
  • Boekholdt S. Matthijs, Kuivenhoven Jan-Albert, Hovingh G. Kees, Jukema J. Wouter, Kastelein John J. P., van Tol Arie CETP gene variation: relation to lipid parameters and cardiovascular risk Current opinion in lipidology 2004;15 (4):393-398 [PubMed]
  • Hovingh G. K., Kuivenhoven J. A., Bisoendial R. J., Groen A. K., van Dam M., van Tol A., Wellington C., Hayden M. R., Smelt A. H. M., Kastelein J. J. P. HDL deficiency and atherosclerosis: lessons from Tangier disease Journal of internal medicine 2004;255 (2):299-301 [PubMed]
  • de Groot Eric, Hovingh G. Kees, Wiegman Albert, Duriez Patrick, Smit Andries J., Fruchart Jean-Charles, Kastelein John J. P. Measurement of arterial wall thickness as a surrogate marker for atherosclerosis Circulation 2004;109 (23 Suppl 1):III33-III38 [PubMed]
  • van der Steeg W. A., Kuivenhoven J. A., Klerkx A. H., Boekholdt S. M., Hovingh G. K., Kastelein J. J. P. Role of CETP inhibitors in the treatment of dyslipidemia Current opinion in lipidology 2004;15 (6):631-636 [PubMed]

2003

  • Kuivenhoven J. A., Hovingh G. K., van Tol A., Jauhiainen M., Ehnholm C., Fruchart J. C., Brinton E. A., Otvos J. D., Smelt A. H. M., Brownlee A., Zwinderman A. H., Hayden M. R., Kastelein J. J. P. Heterozygosity for ABCA1 gene mutations: effects on enzymes, apolipoproteins and lipoprotein particle size Atherosclerosis 2003;171 (2):311-319 [PubMed]
  • Bisoendial Radjesh J., Hovingh G. Kees, Levels Johannes H. M., Lerch Peter G., Andresen Irmgard, Hayden Michael R., Kastelein John J. P., Stroes Erik S. G. Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein Circulation 2003;107 (23):2944-2948 [PubMed]
  • Hovingh G. Kees, van Wijland Michel J. A., Brownlie Alison, Bisoendial Radjesh J., Hayden Michael R., Kastelein John J. P., Groen Albert K. The role of the ABCA1 transporter and cholesterol efflux in familial hypoalphalipoproteinemia Journal of lipid research 2003;44 (6):1251-1255 [PubMed]

2002

  • van Dam Marjel J., de Groot Eric, Clee Susanne M., Hovingh G. Kees, Roelants Roosje, Brooks-Wilson Angie, Zwinderman Aeilko H., Smit Andries J., Smelt August H. M., Groen Albert K., Hayden Michael R., Kastelein John J. P. Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study Lancet 2002;359 (9300):37-41 [PubMed]
  • Bisoendial Radjesh J., Hovingh G. Kees, de Groot Eric, Kastelein John J. P., Lansberg Peter J., Stroes Erik S. G. Measurement of subclinical atherosclerosis: beyond risk factor assessment Current opinion in lipidology 2002;13 (6):595-603 [PubMed]
  • Wellington Cheryl L., Yang Yu-Zhou, Zhou Stephen, Clee Susanne M., Tan Bing, Hirano Kenichi, Zwarts Karin, Kwok Anita, Gelfer Allison, Marcil Michel, Newman Scott, Roomp Kirsten, Singaraja Roshni, Collins Jennifer, Zhang Lin-Hua, Groen Albert K., Hovingh Kees, Brownlie Alison, Tafuri Sherrie, Genest Jacques, Kastelein John J. P., Hayden Michael R. Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol Journal of lipid research 2002;43 (11):1939-1949 [PubMed]

2000

  • Safety and efficacy of granulocyte colony-stimulating factor in kidney and liver transplant recipients Transplant infectious disease 2000;2 (1):15-21 [PubMed]