Prof. PhD C. Ince publications

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Publications Prof. PhD C. Ince

Position
Full Professor
Main activities
Research, Other
Specialisation
Cardiovascular aspects of surgery and intensive care medicine
Focus of research

Cardiovascular aspects of Surgery and Critical Illness.

The Laboratory of Translational Physiology at the Academic Medical Center is dedicated to research into cardiovascular aspects of perioperative medicine (e.g. surgery and intensive care medicine) with an emphasis on organ function, (micro)circulation and cellular and mitochondrial oxygenation. Its research is strongly translational where (pahto)physiological and therapeutic concepts were developed in the laboratory are applied to clinical practice. Research topics include sepsis, acute kidney injury, myocardial depression, ischemia reperfussion, hemorheology, resuscitation and fluid therapy related to surgery and critical care medicine. Basic science interests related to these subjects are focused on renal and heart failure, red blood cell (pahto)physiology, cellular oxygen metabolism, nitric oxide and oxygen radical species and mitochondiral oxygenation and bioenergetics. To carry out these investigations and conduct translational research from bench to bedside we also carry out Research and development on clinical and experimental medical technology which are directed at optical spectroscopy of tissue and mitochondrial oxygenation and clinical microcirculation imaging

2020

  • Parenica Jiri, Kala Petr, Spinar Jindrich, Helanova Katerina, Tesak Martin, Lokaj Petr, Parenica Jiri, Kala Petr, Spinar Jindrich, Helanova Katerina, Tesak Martin, Helan Martin, Lokaj Petr, Mebazaa Alexandre, Legrand Matthieu, Mebazaa Alexandre, Legrand Matthieu, Mebazaa Alexandre, Legrand Matthieu, Littnerova Simona, Benesova Klara, Jarkovský Jiří, Tomandl Josef, Tomandlova Marie, Goldbergová Pavkova Monika, Dastych Milan, Ince Can, Helan Martin, Legrand Matthieu Activation of the Nitric Oxide Pathway and Acute Myocardial Infarction Complicated by Acute Kidney Injury CardioRenal Medicine 2020;10 (2):85-96 [PubMed]
  • Kappler Benjamin, van Tuijl Sjoerd, Ergin B. lent, Fixsen Louis, Stijnen Marco, Ince Can, de Mol Bas A. JM Attenuated cardiac function degradation in ex vivo pig hearts International journal of artificial organs 2020;43 (3):173-179 [PubMed]
  • Tavy Arthur L. M., de Bruin Anton F. J., Smits Anke B., Boerma E. Christiaan, Ince Can, Noordzij Peter G., Boerma Djamila, van Iterson Mat Intestinal Mucosal and Serosal Microcirculation at the Planned Anastomosis during Abdominal Surgery European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 2020;60 (5-6):248-256 [PubMed]
  • Uz Z. hre, Aykut G. çlü, Massey Michael, Ince Yasin, Ergin B. lent, Shen Lucinda, Toraman Fevzi, van Gulik Thomas M., Ince Can Leukocyte-Endothelium Interaction in the Sublingual Microcirculation of Coronary Artery Bypass Grafting Patients Journal of vascular research 2020;57 (1):8-15 [PubMed]
  • Ince Can, de Backer Daniel, Mayeux Philip R. Microvascular Dysfunction in the Critically Ill Critical care clinics 2020;36 (2):323-331
  • Kastelein Arnoud W., Vos Laura M. C., van Baal Juliette O. A. M., Koning Jasper J., Hira Vashendriya V. V., Nieuwland Rienk, van Driel Willemien J., Uz Z. hre, van Gulik Thomas M., van Rheenen Jacco, Ince Can, Roovers Jan-Paul W. R., van Noorden Cornelis J. F., Lok Christianne A. R. Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer Clinical & experimental metastasis 2020 [PubMed]
  • Kappler Benjamin Process and quality control in use of isolated beating porcine slaughterhouse hearts 2020. 196p. ISBN 9789492597335. [UvA Dissertations Online] University of Amsterdam. (Supervisors: de Mol Bastianus. A. J. M., Ince Can; Co-supervisor: Stijnen J. M. A.)
  • He Huaiwu, Long Yun, Liu Dawei, Tang Bo, Ince Can Relationship of relevant factors to P(v-a)CO2/C(a-v)O2 ratio in critically ill patients The Journal of international medical research 2020;48 (1):300060519854633 [PubMed]
  • Arnemann Philip-Helge, Hessler Michael, Kampmeier Tim, Seidel Laura, Malek Youssef, van Aken Hugo, Morelli Andrea, Rehberg Sebastian, Ince Can, Ertmer Christian Resuscitation with hydroxyethyl starch maintains hemodynamic coherence in ovine hemorrhagic shock Anesthesiology 2020;132 (1):131-139 [PubMed]
  • Kastelein Arnoud W., Diedrich Chantal M., de Waal Laura, Ince Can, Roovers Jan-Paul W. R. The vaginal microcirculation after prolapse surgery Neurourology and urodynamics 2020;39 (1):331-338 [PubMed]

2019

  • Shen Lucinda, Uz Zühre, Ince Can, van Gulik Thomas Alterations in intestinal serosal microcirculation precipitated by the Pringle manoeuvre BMJ case reports 2019;12 (1) [PubMed]
  • Erdem Özge, Ince Can, Tibboel Dick, Kuiper Jan Willem Assessing the microcirculation with handheld vital microscopy in critically ill neonates and children: Evolution of the technique and its potential for critical care Frontiers in pediatrics 2019;7 (JULY) [PubMed]
  • Uz Z. hre, Ince Can, Rassam Fadi, Ergin B. lent, van Lienden Krijn P., van Gulik Thomas M. Assessment of hepatic microvascular flow and density in patients undergoing preoperative portal vein embolization HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21 (2):187-194 [PubMed]
  • Erdem Özge, Ince Can, Tibboel Dick, Kuiper Jan Willem Corrigendum: Assessing the Microcirculation With Handheld Vital Microscopy in Critically Ill Neonates and Children: Evolution of the Technique and Its Potential for Critical Care (Frontiers in Pediatrics, (2019), 7, 10.3389/fped.2019.00273) Frontiers in pediatrics 2019;7 [PubMed]
  • Veenstra Gerke, Ince Can, Barendrecht Bart W., Zijlstra Hendrik W., Boerma E. Christiaan Differences in capillary recruitment between cardiac surgery and septic patients after fluid resuscitation Microvascular research 2019;123:14-18 [PubMed]
  • Guerci Philippe, Ergin Bulent, Kapucu Aysegul, Hilty Matthias P., Jubin Ronald, Bakker Jan, Ince Can Effect of Polyethylene-glycolated Carboxyhemoglobin on Renal Microcirculation in a Rat Model of Hemorrhagic Shock Anesthesiology 2019;131 (5):1110-1124 [PubMed]
  • Ferrara Gonzalo, Kanoore Edul Vanina Siham, Caminos Eguillor Juan Francisco, Buscetti María Guillermina, Canales H. ctor Saúl, Lattanzio Bernardo, Gatti Luis, Ince Can, Dubin Arnaldo Effects of fluid and norepinephrine resuscitation in a sheep model of endotoxin shock and acute kidney injury Journal of applied physiology (Bethesda, Md. 2019;127 (3):788-797 [PubMed]
  • He Huaiwu, Hu Qinhe, Long Yun, Wang Xu, Zhang Rui, Su Longxiang, Liu Dawei, Ince Can Effects of high PEEP and fluid administration on systemic circulation, pulmonary microcirculation, and alveoli in a canine model Journal of applied physiology (Bethesda, Md. 2019;127 (1):40-46 [PubMed]
  • Diedrich Chantal M., Kastelein Arnoud W., Verri Filippo M., Weber Maaike A., Ince Can, Roovers Jan-Paul W. R. Effects of topical estrogen therapy on the vaginal microcirculation in women with vulvovaginal atrophy Neurourology and urodynamics 2019;38 (5):1298-1304 [PubMed]
  • Guerci Philippe, Ergin Bulent, Uz Zuhre, Ince Yasin, Westphal Martin, Heger Michal, Ince Can Glycocalyx Degradation Is Independent of Vascular Barrier Permeability Increase in Nontraumatic Hemorrhagic Shock in Rats Anesthesia and analgesia 2019;129 (2):598-607 [PubMed]
  • Brouwer Willem Pieter, Duran Servet, Kuijper Martijn, Ince Can Hemoadsorption with CytoSorb shows a decreased observed versus expected 28-day all-cause mortality in ICU patients with septic shock: A propensity-score-weighted retrospective study Critical care (London, England) 2019;23 (1) [PubMed]
  • Guerci Philippe, Ergin Bulent, Ince Can In Response Anesthesia and analgesia 2019;129 (3):e102-e103 [PubMed]
  • Kappler Benjamin, Ledezma Carlos A., van Tuijl Sjoerd, Meijborg Veronique, Boukens Bastiaan J., Ergin B. lent, Tan P. J., Stijnen Marco, Ince Can, Díaz-Zuccarini Vanessa, de Mol Bas A. J. M. Investigating the physiology of normothermic ex vivo heart perfusion in an isolated slaughterhouse porcine model used for device testing and training BMC cardiovascular disorders 2019;19 (1):254 [PubMed]
  • Slovinski Augusto Passoni, Hajjar Ludhmila Abrahão, Ince Can Microcirculation in Cardiovascular Diseases Journal of cardiothoracic and vascular anesthesia 2019 [PubMed]
  • Guven Goksel, Hilty Matthias P., Ince Can Microcirculation: Physiology, pathophysiology, and clinical application Blood purification 2019:1-8 [PubMed]
  • Hilty Matthias Peter, Guerci Philippe, Ince Yasin, Toraman Fevzi, Ince Can MicroTools enables automated quantification of capillary density and red blood cell velocity in handheld vital microscopy Communications Biology 2019;2 (1) [PubMed]
  • Ackland Gareth L., Brudney Charles S., Cecconi Maurizio, Ince Can, Irwin Michael G., Lacey Jonathan, Pinsky Michael R., Grocott Michael P. W., Mythen Monty G., Edwards Mark R., Miller Timothy E., Sanders Robert, Hughes Finton, Bader Angela, Thompson Annemarie, Hoeft Andreas, Williams David, Shaw Andrew D., Sessler Daniel I., Aronson Sol, Berry Colin, Gan Tong J., Kellum John, Plumb James, Bloomstone Joshua, McEvoy Matthew D., Thacker Julie K. M., Gupta Ruchir, Koepke Elena, Feldheiser Aarne, Levett Denny, Michard Frederic, Hamilton Mark Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine British journal of anaesthesia 2019;122 (5):542-551 [PubMed]
  • Ince Can Physiology and technology for the icu in vivo Critical care (London, England) 2019;23 (Suppl 1):126 [PubMed]
  • Rassam Fadi, Uz Z. hre, van Lienden Krijn P., Ince Can, Bennink Roelof J., van Gulik Thomas M. Quantitative assessment of liver function using hepatobiliary scintigraphy: The effect of microcirculatory alterations after portal vein embolization Nuclear medicine communications 2019;40 (7):720-726 [PubMed]
  • He Huai-Wu, Long Yun, Liu Da-Wei, Ince Can Resuscitation incoherence and dynamic circulation-perfusion coupling in circulatory shock Chinese medical journal 2019;132 (10):1218-1227 [PubMed]
  • Suker Mustafa, Tovar Doncel M. Sherezade, Pinto Lima Alexandre A., Ince Can, van Eijck Casper H. J. Sublingual microcirculation in pancreatico-biliary surgery: An observational study Clinical hemorheology and microcirculation 2019;72 (3):247-257 [PubMed]
  • Erdem Özge, Kuiper Jan Willem, van Rosmalen Joost, Houmes Robert Jan, Wildschut Enno D., Ince Can, Tibboel Dick The sublingual microcirculation throughout neonatal and pediatric extracorporeal membrane oxygenation treatment: Is it altered by systemic extracorporeal support? Frontiers in pediatrics 2019;7 (JULY) [PubMed]
  • Marini John J., Debacker Daniel, Gattinoni Luciano, Ince Can, Martin-Loeches Ignacio, Singer Pierre, Singer Mervyn, Westphal Martin, Vincent Jean-Louis Thinking forward: Promising but unproven ideas for future intensive care Critical care (London, England) 2019;23 [PubMed]
  • Kastelein Arnoud W., Diedrich Chantal M., Jansen Charlotte H. J. R., Zwolsman Sandra E., Ince Can, Roovers Jan-Paul W. R. Validation of noninvasive focal depth measurements to determine epithelial thickness of the vaginal wall Menopause (New York, N.Y.) 2019;26 (10):1160-1165 [PubMed]

2018

  • Hessler Michael, Arnemann Philip-Helge, Zamit Frédéric, Seidel Laura, Kampmeier Tim-Gerald, Kathöfer Ulrich, Morelli Andrea, Ince Can, Rehberg Sebastian W., Ertmer Christian A new complimentary web-based tool for manual analysis of microcirculation videos: Validation of the Capillary Mapper against the current gold standard AVA 3.2 Microcirculation (New York, N.Y. 2018;25 (8) [PubMed]
  • Wernly Bernhard, Lichtenauer Michael, Vellinga Namkje A. R., Boerma E. Christiaan, Ince Can, Kelm Malte, Jung Christian Blood urea nitrogen (BUN) independently predicts mortality in critically ill patients admitted to ICU: A multicenter study Clinical hemorheology and microcirculation 2018;69 (1-2):123-131 [PubMed]
  • de Bruin A. F. J., Tavy A. L. M., van der Sloot K., Smits A., Ince C., Boerma E. C., Noordzij P. G., Boerma D., van Iterson M. Can sidestream dark field (SDF) imaging identify subtle microvascular changes of the bowel during colorectal surgery? Techniques in coloproctology 2018;22 (10):793-800 [PubMed]
  • Akin Sakir Clinical Features of Short- and Long-term Mechanical Circulatory Support: Klinische aspecten van korte en lange termijn mechanische circulatie ondersteuning 2018. 361p. ISBN 9789463801553. [UvA Dissertations Online] Erasmus University Rotterdam: -. (Supervisor: Ince Can)
  • He Huaiwu, Liu Dawei, Ince Can Colloids and the Microcirculation Anesthesia and analgesia 2018;126 (5):1747–1754 [PubMed]
  • Legrand Matthieu, Ait-Oufella Hafid, Ince Can Could resuscitation be based on microcirculation data? Yes Intensive care medicine 2018;44 (6):944-946 [PubMed]
  • Ergin Bulent, Zuurbier Coert J., Kapucu Aysegul, Ince Can Divergent Effects of Hypertonic Fluid Resuscitation on Renal Pathophysiological and Structural Parameters in Rat Model of Lower Body Ischemia/Reperfusion-Induced Sterile Inflammation Shock (Augusta, Ga.) 2018;50 (6):655-663 [PubMed]
  • Lima Alexandre, van Rooij Tom, Ergin Bulent, Sorelli Michele, Ince Yasin, Specht Patricia A. C., Mik Egbert G., Bocchi Leonardo, Kooiman Klazina, de Jong Nico, Ince Can Dynamic contrast-enhanced ultrasound identifies microcirculatory alterations in sepsis-induced acute kidney injury Critical care medicine 2018;46 (8):1284-1292 [PubMed]
  • He Huaiwu, Gruartmoner Guillem, Ince Yilmaz, Henegouwen Mark I. van Berge, Gisbertz Suzanne S., Geerts Bart F., Ince Can, Hollmann Markus W., Liu Dawei, Veelo Denise P. Effect of pneumoperitoneum and steep reverse-Trendelenburg position on mean systemic filling pressure, venous return, and microcirculation during esophagectomy Journal of thoracic disease 2018;10 (6):3399-3408 [PubMed]
  • Tavy A. L. M., de Bruin A. F. J., van der Sloot K., Boerma E. C., Ince C., Noordzij P. G., Boerma D., van Iterson M. Effects of Thoracic Epidural Anaesthesia on the Serosal Microcirculation of the Human Small Intestine World journal of surgery 2018;42 (12):3911-3917 [PubMed]
  • Uz Z. hre, van Gulik Thomas M., Aydemirli Mehtap D., Guerci Philippe, Ince Yasin, Cuppen Diede, Ergin Bulent, Aksu Ugur, de Mol Bas A., Ince Can Identification and quantification of human microcirculatory leukocytes using handheld video microscopes at the bedside Journal of applied physiology (Bethesda, Md. 2018;124 (6):1550-1557 [PubMed]
  • Uz Z. hre, Kastelein Arnoud W., Milstein Dan M. J., Liu Dan, Rassam Fadi, Veelo Denise P., Roovers Jan-Paul W. R., Ince Can, van Gulik Thomas M. Intraoperative Incident Dark Field Imaging of the Human Peritoneal Microcirculation Journal of vascular research 2018;55 (3):136-143 [PubMed]
  • Scorcella Claudia, Damiani Elisa, Domizi Roberta, Pierantozzi Silvia, Tondi Stefania, Carsetti Andrea, Ciucani Silvia, Monaldi Valentina, Rogani Mara, Marini Benedetto, Adrario Erica, Romano Rocco, Ince Can, Boerma E. Christiaan, Donati Abele MicroDAIMON study: Microcirculatory DAIly MONitoring in critically ill patients: a prospective observational study Annals of intensive care 2018;8 (1) [PubMed]
  • Wernly Bernhard, Lichtenauer Michael, Vellinga Namkje, Boerma Christiaan, Ince Can, Kelm Malte, Jung Christian Model for End-Stage Liver Disease Excluding INR (MELD-XI) score is associated with hemodynamic impairment and predicts mortality in critically ill patients European journal of internal medicine 2018;51:80-84 [PubMed]
  • Harki Jihan, Suker Mustafa, Tovar-Doncel M. Sherezade, van Dijk Louisa J. D., van Noord D. sirée, van Eijck Casper H. J., Bruno Marco J., Kuipers Ernst J., Ince Can Patients with chronic mesenteric ischemia have an altered sublingual microcirculation Clinical and experimental gastroenterology 2018;11:405-414 [PubMed]
  • Guven Goksel, Brankovic Milos, Constantinescu Alina A., Brugts Jasper J., Hesselink Dennis A., Akin Sakir, Struijs Ard, Birim Ozcan, Ince Can, Manintveld Olivier C., Caliskan Kadir Preoperative right heart hemodynamics predict postoperative acute kidney injury after heart transplantation Intensive care medicine 2018;44 (5):588-597 [PubMed]
  • Uz Zühre, Ince Can, Guerci Philippe, Ince Yasin, P Araujo Renata, Ergin Bulent, Hilty Matthias P, van Gulik Thomas M, de Mol Bas A Recruitment of sublingual microcirculation using handheld incident dark field imaging as a routine measurement tool during the postoperative de-escalation phase-a pilot study in post ICU cardiac surgery patients Perioperative medicine (London, England) 2018;7:18 [PubMed]
  • Ince Can, Boerma E. Christiaan, Cecconi Maurizio, de Backer Daniel, Shapiro Nathan I., Duranteau Jacques, Pinsky Michael R., Artigas Antonio, Teboul Jean-Louis, Reiss Irwin K. M., Aldecoa Cesar, Hutchings Sam D., Donati Abele, Maggiorini Marco, Taccone Fabio S., Hernandez Glenn, Payen Didier, Tibboel Dick, Martin Daniel S., Zarbock Alexander, Monnet Xavier, Dubin Arnaldo, Bakker Jan, Vincent Jean-Louis, Scheeren Thomas W. L. Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine Intensive care medicine 2018;44 (3):281-299 [PubMed]
  • Uz Zühre, de Mol Bastianus Ajm, van Gulik Thomas M., Ince Can Sublingual microcirculation reveals fluid overload and leukocytosis in a post-cardiac surgery patient BMJ case reports 2018;2018 [PubMed]
  • Kanoore Edul Vanina S. The microcirculation in health and states of shock 2018. ISBN 9789493019874. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisor: Dubin A.)
  • Ergin Bulent The renal microcirculation as a target for the treatment of acute kidney injury in models of critical illness 2018. ISBN 9789463800518. [UvA Dissertations Online] Erasmus University Rotterdam: ErasmusMC. (Supervisors: Gommers D. A. M. P. J., Ince Can, Zuurbier C. J.)
  • Veenstra Gerke The response of the microcirculation during fluid shifts 2018. ISBN 9789402812268. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisor: Boerma E. C.)

2017

  • Guerci Philippe, Ince Yasin, Heeman Paul, Faber Dirk J., Ergin Bulent, Ince Can A LED-based phosphorimeter for measurement of microcirculatory oxygen pressure Journal of applied physiology (Bethesda, Md. 2017;122 (2):307-316 [PubMed]
  • Hilty Matthias Peter, Pichler Jacqueline, Ergin Bulent, Hefti Urs, Merz Tobias Michael, Ince Can, Maggiorini Marco Assessment of endothelial cell function and physiological microcirculatory reserve by video microscopy using a topical acetylcholine and nitroglycerin challenge Intensive Care Medicine Experimental 2017;5 (1):26 [PubMed]
  • Ince Can Blood Transfusions Correct Anemia and Improve Tissue Oxygenation in Surgical and Critically ill Patients Turkish journal of anaesthesiology and reanimation 2017;45 (3):119-121 [PubMed]
  • Uz Zühre, Milstein Dan M. J., Ince Can, de Mol Bastian A. J. M. Circulating microaggregates during cardiac surgery precedes postoperative stroke Journal of thrombosis and thrombolysis 2017;44 (1):14-18 [PubMed]
  • ten Tusscher Birkitt, Gudden Corien, van Vliet Suus, Smit Bob, Ince Can, Boerma E. Christiaan, de Grooth Harm-Jan S., Elbers Paul W. G. Focus on focus: lack of coherence between systemic and microvascular indices of oedema formation Anaesthesiology intensive therapy 2017;49 (5):350-357 [PubMed]
  • Akin Sakir, Dos Reis Miranda Dinis, Caliskan Kadir, Soliman Osama I., Guven Goksel, Struijs Ard, van Thiel Robert J., Jewbali Lucia S., Lima Alexandre, Gommers Diederik, Zijlstra Felix, Ince Can Functional evaluation of sublingual microcirculation indicates successful weaning from VA-ECMO in cardiogenic shock Critical care (London, England) 2017;21 (1):265 [PubMed]
  • Damiani Elisa, Ince Can, Scorcella Claudia, Domizi Roberta, Carsetti Andrea, Mininno Nicoletta, Pierantozzi Silvia, Adrario Erica, Romano Rocco, Pelaia Paolo, Donati Abele Impact of microcirculatory video quality on the evaluation of sublingual microcirculation in critically ill patients Journal of clinical monitoring and computing 2017;31 (5):981-988 [PubMed]
  • Ince Can Intensive care medicine in 2050: the ICU in vivo Intensive care medicine 2017;43 (11):1700-1702 [PubMed]
  • Daeichin Verya, van Rooij Tom, Skachkov Ilya, Ergin Bulent, Specht Patricia A. C., Lima Alexandre, Ince Can, Bosch Johan G., van der Steen Antonius F. W., de Jong Nico, Kooiman Klazina Microbubble Composition and Preparation for High-Frequency Contrast-Enhanced Ultrasound Imaging: In Vitro and In Vivo Evaluation IEEE transactions on ultrasonics, ferroelectrics, and frequency control 2017;64 (3):555-567 [PubMed]
  • Gruartmoner G., Mesquida J., Ince C. Microcirculatory monitoring in septic patients: Where do we stand? Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias 2017;41 (1):44-52 [PubMed]
  • Vellinga Namkje A. R., Boerma E. Christiaan, Koopmans Matty, Donati Abele, Dubin Arnaldo, Shapiro Nathan I., Pearse Rupert M., van der Voort Peter H. J., Dondorp Arjen M., Bafi Tony, Fries Michael, Akarsu-Ayazoglu Tulin, Pranskunas Andrius, Hollenberg Steven, Balestra Gianmarco, van Iterson Mat, Sadaka Farid, Minto Gary, Aypar Ulku, Hurtado F. Javier, Martinelli Giampaolo, Payen Didier, van Haren Frank, Holley Anthony, Gomez Hernando, Mehta Ravindra L., Rodriguez Alejandro H., Ruiz Carolina, Canales Héctor S., Duranteau Jacques, Spronk Peter E., Jhanji Shaman, Hubble Sheena, Chierego Marialuisa, Jung Christian, Martin Daniel, Sorbara Carlo, Bakker Jan, Ince Can, Koopmans M., van Iterson M., van der Voort P. H. J., Bakker J., Ruiz C., Bafi A. T., Dubin A., Kanoore Edul V. S., Canales H. S., Hurtado F. J., Hollenberg S. M. Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis Critical care (London, England) 2017;21 (1):255 [PubMed]
  • Ergin Bulent, Heger Michal, Kandil Asli, Demirci-Tansel Cihan, Ince Can Mycophenolate mofetil improves renal haemodynamics, microvascular oxygenation, and inflammation in a rat model of supra-renal aortic clamping-mediated renal ischaemia reperfusion injury Clinical and experimental pharmacology & physiology 2017;44 (2):294-304 [PubMed]
  • Sorelli Michele, Ince Can, Bocchi Leonardo Particle tracking for the assessment of microcirculatory perfusion Physiological measurement 2017;38 (2):358-373 [PubMed]
  • Ince Can Personalized physiological medicine Critical care (London, England) 2017;21 (3):308 [PubMed]
  • Marini John J., de Backer Daniel, Ince Can, Singer Mervyn, van Haren Frank, Westphal Martin, Wischmeyer Paul Seven unconfirmed ideas to improve future ICU practice Critical care (London, England) 2017;21 (3):315 [PubMed]
  • Ferrara Gonzalo, Edul Vanina S. Kanoore, Canales Héctor S., Martins Enrique, Canullán Carlos, Murias Gastón, Pozo Mario O., Caminos Eguillor Juan F., Buscetti María G., Ince Can, Dubin Arnaldo Systemic and microcirculatory effects of blood transfusion in experimental hemorrhagic shock Intensive Care Medicine Experimental 2017;5 (1):24 [PubMed]
  • Guerci Philippe, Ergin Bulent, Ince Can The macro- and microcirculation of the kidney Best practice & research. Clinical anaesthesiology 2017;31 (3):315-329 [PubMed]
  • Veenstra Gerke, Pranskunas Andrius, Skarupskiene Inga, Pilvinis Vidas, Hemmelder Marc H., Ince Can, Boerma E. Christiaan Ultrafiltration rate is an important determinant of microcirculatory alterations during chronic renal replacement therapy BMC nephrology 2017;18 (1):71 [PubMed]
  • He Huai-Wu, Liu Da-Wei, Ince Can Understanding elevated Pv-aCO2 gap and Pv-aCO2/Ca-vO2 ratio in venous hyperoxia condition Journal of clinical monitoring and computing 2017;31 (6):1321-1323 [PubMed]
  • Erdem Özge, Kuiper Jan Willem, Ince Can, Tibboel Dick Videomicroscopic investigation of the microcirculation requires uniform definitions Physiological reports 2017;5 (11):e13303 [PubMed]

2016

  • Gilbert-Kawai Edward, Coppel Jonny, Bountziouka Vassiliki, Ince Can, Martin Daniel, Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H., Morgan G., Morgan J., Murray A., Mythen M., Newman S., O'Dwyer M., Pate J. A comparison of the quality of image acquisition between the incident dark field and sidestream dark field video-microscopes BMC medical imaging 2016;16 (1):10 [PubMed]
  • van Elteren Hugo A., de Jonge Rogier C. J., van Rosmalen Joost, Ince Can, Reiss Irwin K. M. Adaptation of the Cutaneous Microcirculation in Preterm Neonates Microcirculation (New York, N.Y. 2016;23 (6):468-474 [PubMed]
  • Zafrani Lara, Ergin Bulent, Kapucu Aysegul, Ince Can Blood transfusion improves renal oxygenation and renal function in sepsis-induced acute kidney injury in rats Critical care (London, England) 2016;20 (1):406 [PubMed]
  • Akin S., Ince C., Dos Reis Miranda D. Cardiovascular Response to ECMOin: Jean-Louis Vincent, editors. Annual Update in Intensive Care and Emergency Medicine 2016. Switzerland: Springer International Publishing; 2016. p. 185-194, ISBN 9783319273488; 9783319273495
  • Gilbert-Kawai Edward, Coppel Jonny, Phillip Hennis, Grocott Michael, Ince Can, Martin Daniel Changes in labial capillary density on ascent to and descent from high altitude F1000Research 2016;5:2107 [PubMed]
  • Yuruk K., Bezemer R., Euser M., Milstein D. M., Almac E., van den Brink A., Scholten E. W., de Mol B. A. J. M., Ince C. Conventional versus miniaturized ECC during CABG surgery and the effects on the microcirculation. Annals of thoracic surgery 2016
  • Peters Esther, Ergin Bülent, Kandil Asli, Gurel-Gurevin Ebru, van Elsas Andrea, Masereeuw Rosalinde, Pickkers Peter, Ince Can Effects of a human recombinant alkaline phosphatase on renal hemodynamics, oxygenation and inflammation in two models of acute kidney injury Toxicology and applied pharmacology 2016;313:88-96 [PubMed]
  • Ergin Bulent, Guerci Philippe, Zafrani Lara, Nocken Frank, Kandil Asli, Gurel-Gurevin Ebru, Demirci-Tansel Cihan, Ince Can Effects of N-acetylcysteine (NAC) supplementation in resuscitation fluids on renal microcirculatory oxygenation, inflammation, and function in a rat model of endotoxemia Intensive Care Medicine Experimental 2016;4 (1):29 [PubMed]
  • Damiani Elisa, Ince Can, Orlando Fiorenza, Pierpaoli Elisa, Cirioni Oscar, Giacometti Andrea, Mocchegiani Federico, Pelaia Paolo, Provinciali Mauro, Donati Abele Effects of the Infusion of 4% or 20% Human Serum Albumin on the Skeletal Muscle Microcirculation in Endotoxemic Rats PLoS ONE 2016;11 (3):e0151005 [PubMed]
  • Weber Maaike A., Diedrich Chantal M., Ince Can, Roovers Jan-Paul Focal depth measurements of the vaginal wall: a new method to noninvasively quantify vaginal wall thickness in the diagnosis and treatment of vaginal atrophy Menopause (New York, N.Y.) 2016;23 (8):833-838 [PubMed]
  • Donati Abele From macrohemodynamic to the microcirculation 2016. 281p. ISBN 9789461827050. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.)
  • Ergin Bulent, Zafrani Lara, Kandil Asli, Baasner Silke, Lupp Corinna, Demirci Cihan, Westphal Martin, Ince Can Fully Balanced Fluids do not Improve Microvascular Oxygenation, Acidosis and Renal Function in a Rat Model of Endotoxemia Shock (Augusta, Ga.) 2016;46 (1):83-91 [PubMed]
  • Ince Can, Ertmer Christian Hemodynamic coherence: Its meaning in perioperative and intensive care medicine Preface Best practice & research. Clinical anaesthesiology 2016;30 (4):395-397 [PubMed]
  • Rabb Hamid, Griffin Matthew D., McKay Dianne B., Swaminathan Sundararaman, Pickkers Peter, Rosner Mitchell H., Kellum John A., Ronco Claudio, Kellum John, Okusa Mark, Rosner Mitchell, Agarwal Anupam, Basile David P., Blantz Roland, Bonventre Joseph V., Cantaluppi Vincenzo, Chawla Lakhmir S., Dong Zheng, Griffin Matthew, Harris Raymond, Humphreys Benjamin, Ince Can, Matejovic Martin, McKay Dianne, Mehta Ravindra, Molitoris Bruce, Murray Patrick, Nangaku Masaomi, Portilla Didier, Singbartl Kai, Unwin Robert, Yang Li Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps Journal of the American Society of Nephrology 2016;27 (2):371-379 [PubMed]
  • Ferrara Gonzalo, Kanoore Edul Vanina Siham, Martins Enrique, Canales Héctor Saúl, Canullán Carlos, Murias Gastón, Pozo Mario Omar, Estenssoro Elisa, Ince Can, Dubin Arnaldo Intestinal and sublingual microcirculation are more severely compromised in hemodilution than in hemorrhage Journal of applied physiology (Bethesda, Md. 2016;120 (10):1132-1140 [PubMed]
  • Legrand Matthieu, Ince Can Intravenous Fluids in AKI: A Mechanistically Guided Approach Seminars in nephrology 2016;36 (1):53-61 [PubMed]
  • Weber M. A., Milstein D. M. J., Ince C., Roovers J. P. W. R. Is pelvic organ prolapse associated with altered microcirculation of the vaginal wall? Neurourology and urodynamics 2016;35 (7):764-770 [PubMed]
  • Milstein Dan M. J., Ince Can, Gisbertz Suzanne S., Boateng Kofi B., Geerts Bart F., Hollmann Markus W., van Berge Henegouwen Mark I., Veelo Denise P. Laser speckle contrast imaging identifies ischemic areas on gastric tube reconstructions following esophagectomy Medicine 2016;95 (25):e3875 [PubMed]
  • Ince Can, Mik Egbert G. Microcirculatory and mitochondrial hypoxia in sepsis, shock, and resuscitation Journal of applied physiology (Bethesda, Md. 2016;120 (2):226-235 [PubMed]
  • Kara Atila, Akin Sakir, Dos Reis Miranda Dinis, Struijs Ard, Caliskan Kadir, van Thiel Robert J., Dubois Eric A., de Wilde Wouter, Zijlstra Felix, Gommers Diederik, Ince Can Microcirculatory assessment of patients under VA-ECMO Critical care (London, England) 2016;20 (1):344 [PubMed]
  • Ocak Işık, Kara Atila, Ince Can Monitoring microcirculation Best practice & research. Clinical anaesthesiology 2016;30 (4):407-418 [PubMed]
  • Kara Atila, Akin Sakir, Ince Can Monitoring microcirculation in critical illness Current opinion in critical care 2016;22 (5):444-452 [PubMed]
  • Ashruf J. F., Ince C. Myocardial Microcirculation and Mitochondrial Energetics in the Isolated Rat Heart Advances in experimental medicine and biology 2016;876:159-165 [PubMed]
  • Basile David P., Bonventre Joseph V., Mehta Ravindra, Nangaku Masaomi, Unwin Robert, Rosner Mitchell H., Kellum John A., Ronco Claudio, Kellum John, Okusa Mark, Rosner Mitchell, Agarwal Anupam, Blantz Roland, Cantaluppi Vincenzo, Chawla Lakhmir S., Dong Zheng, Griffin Matthew, Harris Raymond, Humphreys Benjamin, Ince Can, Matejovic Martin, McKay Dianne, Molitoris Bruce, Murray Patrick, Pickkers Peter, Portilla Didier, Rabb Hamid, Singbartl Kai, Swaminathan Sundararaman, Yang Li Progression after AKI: Understanding Maladaptive Repair Processes to Predict and Identify Therapeutic Treatments Journal of the American Society of Nephrology 2016;27 (3):687-697 [PubMed]
  • Matejovic Martin, Ince Can, Chawla Lakhmir S., Blantz Roland, Molitoris Bruce A., Rosner Mitchell H., Okusa Mark D., Kellum John A., Ronco Claudio, Kellum John, Okusa Mark, Rosner Mitchell, Agarwal Anupam, Basile David P., Bonventre Joseph V., Cantaluppi Vincenzo, Dong Zheng, Griffin Matthew, Harris Raymond, Humphreys Benjamin, McKay Dianne, Mehta Ravindra, Molitoris Bruce, Murray Patrick, Nangaku Masaomi, Pickkers Peter, Portilla Didier, Rabb Hamid, Singbartl Kai, Swaminathan Sundararaman, Unwin Robert, Yang Li Renal Hemodynamics in AKI: In Search of New Treatment Targets Journal of the American Society of Nephrology 2016;27 (1):49-58 [PubMed]
  • Edul Vanina S. Kanoore, Ince Can, Vazquez Alejandro Risso, Rubatto Paolo N., Espinoza Emilio D. Valenzuela, Welsh Sebastián, Enrico Carolina, Dubin Arnaldo Similar Microcirculatory Alterations in Patients with Normodynamic and Hyperdynamic Septic Shock Annals of the American Thoracic Society 2016;13 (2):240-247 [PubMed]
  • Humphreys Benjamin D., Cantaluppi Vincenzo, Portilla Didier, Singbartl Kai, Yang Li, Rosner Mitchell H., Kellum John A., Ronco Claudio, Okusa Mark, Agarwal Anupam, Basile David P., Blantz Roland, Bonventre Joseph V., Chawla Lakhmir S., Dong Zheng, Griffin Matthew, Harris Raymond, Ince Can, Matejovic Martin, McKay Dianne, Mehta Ravindra, Molitoris Bruce, Murray Patrick, Nangaku Masaomi, Pickkers Peter, Rabb Hamid, Swaminathan Sundararaman, Unwin Robert Targeting Endogenous Repair Pathways after AKI Journal of the American Society of Nephrology 2016;27 (4):990-998 [PubMed]
  • Aksu Ugur, Bezemer R., Yavuz B., Demirci C., Ince C. The effects of balanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock on renal oxygenation, nitric oxide metabolism, and reactive oxygen species Shock (Augusta, Ga.) 2016
  • Ince Can, Mayeux Philip R., Nguyen Trung, Gomez Hernando, Kellum John A., Ospina-Tascón Gustavo A., Hernandez Glenn, Murray Patrick, de Backer Daniel THE ENDOTHELIUM IN SEPSIS Shock (Augusta, Ga.) 2016;45 (3):259-270 [PubMed]
  • Okusa Mark D., Rosner Mitchell H., Kellum John A., Ronco Claudio, Kellum John, Okusa Mark, Rosner Mitchell, Agarwal Anupam, Basile David P., Blantz Roland, Bonventre Joseph V., Cantaluppi Vincenzo, Chawla Lakhmir S., Dong Zheng, Griffin Matthew, Harris Raymond, Humphreys Benjamin, Ince Can, Matejovic Martin, McKay Dianne, Mehta Ravindra, Molitoris Bruce, Murray Patrick, Nangaku Masaomi, Pickkers Peter, Portilla Didier, Rabb Hamid, Singbartl Kai, Swaminathan Sundararaman, Unwin Robert, Yang Li Therapeutic Targets of Human AKI: Harmonizing Human and Animal AKI Journal of the American Society of Nephrology 2016;27 (1):44-48 [PubMed]
  • Kara Atila, Akin Sakir, Ince Can The response of the microcirculation to cardiac surgery Current opinion in anaesthesiology 2016;29 (1):85-93 [PubMed]
  • Akin Sakir, Kara Atila, den Uil Corstiaan A., Ince Can The response of the microcirculation to mechanical support of the heart in critical illness Best practice & research. Clinical anaesthesiology 2016;30 (4):511-522 [PubMed]
  • Ergin B., Kapucu A., Guerci P., Ince C. The role of bicarbonate precursors in balanced fluids during haemorrhagic shock with and without compromised liver function British journal of anaesthesia 2016;117 (4):521-528 [PubMed]
  • Kuiper J. W., Tibboel D., Ince C. The vulnerable microcirculation in the critically ill pediatric patient Critical care (London, England) 2016;20 (1):352 [PubMed]
  • Ince Can, Guerci Philippe Why and when the microcirculation becomes disassociated from the macrocirculation Intensive care medicine 2016;42 (10):1645-1646 [PubMed]

2015

  • Marini John J., Gattinoni Luciano, Ince Can, Kozek-Langenecker Sibylle, Mehta Ravindra L., Pichard Claude, Westphal Martin, Wischmeyer Paul, Vincent Jean-Louis A few of our favorite unconfirmed ideas Critical care (London, England) 2015;19 (3):S1 [PubMed]
  • van Elteren H. A., Ince C., Tibboel D., Reiss I. K. M., de Jonge R. C. J. Cutaneous microcirculation in preterm neonates: comparison between sidestream dark field (SDF) and incident dark field (IDF) imaging Journal of clinical monitoring and computing 2015;29 (5):543-548 [PubMed]
  • Aykut Guclu, Veenstra Gerke, Scorcella Claudia, Ince Can, Boerma Christiaan Cytocam-IDF (incident dark field illumination) imaging for bedside monitoring of the microcirculation Intensive Care Medicine Experimental 2015;3 (1):40 [PubMed]
  • Pérez-Bárcena Jon, Romay Eduardo, Llompart-Pou Juan Antonio, Ibáñez Javier, Brell Marta, Llinás Pedro, González Elsa, Merenda Amedeo, Ince Can, Bullock Ross Direct observation during surgery shows preservation of cerebral microcirculation in patients with traumatic brain injury Journal of the neurological sciences 2015;353 (1-2):38-43 [PubMed]
  • López Alejandra, Grignola Juan Carlos, Angulo Martín, Alvez Ignacio, Nin Nicolás, Lacuesta Gonzalo, Baz Manuel, Cardinal Pablo, Prestes Ivana, Bouchacourt Juan P., Riva Juan, Ince Can, Hurtado Francisco Javier Effects of early hemodynamic resuscitation on left ventricular performance and microcirculatory function during endotoxic shock Intensive Care Medicine Experimental 2015;3 (1):49 [PubMed]
  • Vellinga Namkje A. R., Veenstra Gerke, Scorcella Claudia, Koopmans Matty, van Roon Eric N., Ince Can, Boerma E. Christiaan Effects of ketanserin on microcirculatory alterations in septic shock: An open-label pilot study Journal of critical care 2015;30 (6):1156-1162 [PubMed]
  • Ferrara Gonzalo, Kanoore Edul Vanina S., Caminos Eguillor Juan F., Martins Enrique, Canullán Carlos, Canales Héctor S., Ince Can, Estenssoro Elisa, Dubin Arnaldo Effects of norepinephrine on tissue perfusion in a sheep model of intra-abdominal hypertension Intensive Care Medicine Experimental 2015;3 (1):46 [PubMed]
  • Gruartmoner G., Mesquida J., Ince Can Fluid therapy and the hypovolemic microcirculation Current opinion in critical care 2015;21 (4):276-284 [PubMed]
  • Meinders Arend-Jan, Nieuwenhuis Laurens, Ince Can, Bos Willem-Jan, Elbers Paul W. G. Haemodialysis Impairs the Human Microcirculation Independent from Macrohemodynamic Parameters Blood purification 2015;40 (1):38-44 [PubMed]
  • Ince Can Hemodynamic coherence and the rationale for monitoring the microcirculation Critical care (London, England) 2015;19 (3):S8 [PubMed]
  • Vellinga Namkje A. R., Boerma E. Christiaan, Koopmans Matty, Donati Abele, Dubin Arnaldo, Shapiro Nathan I., Pearse Rupert M., Machado Flavia R., Fries Michael, Akarsu-Ayazoglu Tulin, Pranskunas Andrius, Hollenberg Steven, Balestra Gianmarco, van Iterson Mat, van der Voort Peter H. J., Sadaka Farid, Minto Gary, Aypar Ulku, Hurtado F. Javier, Martinelli Giampaolo, Payen Didier, van Haren Frank, Holley Anthony, Pattnaik Rajyabardhan, Gomez Hernando, Mehta Ravindra L., Rodriguez Alejandro H., Ruiz Carolina, Canales Héctor S., Duranteau Jacques, Spronk Peter E., Jhanji Shaman, Hubble Sheena, Chierego Marialuisa, Jung Christian, Martin Daniel, Sorbara Carlo, Tijssen Jan G. P., Bakker Jan, Ince Can, Koopmans M., van Iterson M., van der Voort P. H. J., Bakker J., van Bommel J., Ruiz C., Hernandez G., Machado F. R., Bafi A. T., Dubin A. International study on microcirculatory shock occurrence in acutely ill patients Critical care medicine 2015;43 (1):48-56 [PubMed]
  • Zafrani Lara, Ince Can Microcirculation in Acute and Chronic Kidney Diseases American journal of kidney diseases 2015;66 (6):1083-1094 [PubMed]
  • Sorelli M., Bocchi L., Ince C. Monitoring the microcirculation at the bedside using hand-held imaging microscopes: Automatic tracking of erythrocytes Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2015;2015:7378-7381 [PubMed]
  • Ashruf Jesse Feisal Myocardial microcirculation and mitochondrial energetics in the isolated rat heart 2015. 152p. ISBN 9789491715075. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisors: Zuurbier C. J., Milstein D. M. J.)
  • Balestra Gianmarco M., Aalders Maurice C. G., Specht Patricia A. C., Ince Can, Mik Egbert G. Oxygenation measurement by multi-wavelength oxygen-dependent phosphorescence and delayed fluorescence: catchment depth and application in intact heart Journal of biophotonics 2015;8 (8):615-628 [PubMed]
  • Damiani Elisa, Adrario Erica, Luchetti Michele Maria, Scorcella Claudia, Carsetti Andrea, Mininno Nicoletta, Pierantozzi Silvia, Principi Tiziana, Strovegli Daniele, Bencivenga Rosella, Gabrielli Armando, Romano Rocco, Pelaia Paolo, Ince Can, Donati Abele Plasma free hemoglobin and microcirculatory response to fresh or old blood transfusions in sepsis PLoS ONE 2015;10 (5):e0122655 [PubMed]
  • Aksu Ugur Renal perfusion and oxygenation during acute kidney injury 2015. 150p. ISBN 9789491715082. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisor: Bezemer R.)
  • van den Berg Victor J., van Elteren Hugo A., Buijs Erik A. B., Ince Can, Tibboel Dick, Reiss Irwin K. M., de Jonge Rogier C. J. Reproducibility of Microvascular Vessel Density Analysis in Sidestream Dark-Field-Derived Images of Healthy Term Newborns Microcirculation (New York, N.Y. 2015;22 (1):37-43 [PubMed]
  • Aksu Ugur, Ergin Bulent, Bezemer Rick, Kandil Asli, Milstein Dan M. J., Demirci-Tansel Cihan, Ince Can Scavenging reactive oxygen species using tempol in the acute phase of renal ischemia/reperfusion and its effects on kidney oxygenation and nitric oxide levels Intensive Care Medicine Experimental 2015;3 (1):57 [PubMed]
  • Kanoore Edul Vanina S., Ince Can, Estenssoro Elisa, Ferrara Gonzalo, Arzani Yanina, Salvatori Carolina, Dubin Arnaldo The Effects of Arterial Hypertension and Age on the Sublingual Microcirculation of Healthy Volunteers and Outpatients with Cardiovascular Risk Factors Microcirculation (New York, N.Y. 2015;22 (6):485-492 [PubMed]
  • Zafrani Lara, Payen Didier, Azoulay Elie, Ince Can The microcirculation of the septic kidney Seminars in nephrology 2015;35 (1):75-84 [PubMed]
  • Ergin Bulent, Kapucu Aysegul, Demirci-Tansel Cihan, Ince Can The renal microcirculation in sepsis Nephrology, dialysis, transplantation 2015;30 (2):169-177 [PubMed]
  • Ince Can To beta block or not to beta block; that is the question Critical care (London, England) 2015;19 (1):339 [PubMed]
  • Weber Maaike A., Milstein Dan M. J., Ince Can, Oude Rengerink Katrien, Roovers Jan-Paul W. R. Vaginal microcirculation: Non-invasive anatomical examination of the micro-vessel architecture, tortuosity and capillary density Neurourology and urodynamics 2015;34 (8):723-729 [PubMed]
  • Kanoore Edul Vanina S., Ince Can, Dubin Arnaldo What is microcirculatory shock? Current opinion in critical care 2015;21 (3):245-252 [PubMed]

2014

  • Buijs E. A., Houmes R. J., Rizopoulos D., Wildschut E. D., Reiss I. K., Ince C., Tibboel D. Arterial lactate for predicting mortality in children requiring extracorporeal membrane oxygenation Minerva anestesiologica 2014;80 (12):1282-1293 [PubMed]
  • Bikker Ido G., Holland Wim, Specht Patricia, Ince Can, Gommers Diederik Assessment of ventilation inhomogeneity during mechanical ventilation using a rapid-response oxygen sensor-based oxygen washout method Intensive Care Medicine Experimental 2014;2 (1):11 [PubMed]
  • Gomez Hernando, Ince Can, de Backer Daniel, Pickkers Peter, Payen Didier, Hotchkiss John, Kellum John A. A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury Shock (Augusta, Ga.) 2014;41 (1):3-11 [PubMed]
  • Almac Emre, Bezemer Rick, Kandil Asli, Aksu Ugur, Milstein Dan M. J., Bakker Jan, Demirci-Tansel Cihan, Ince Can Bis maltolato oxovanadium (BMOV) and ischemia/reperfusion-induced acute kidney injury in rats Intensive Care Medicine Experimental 2014;2 (1):6 [PubMed]
  • Smorenberg Annemieke, Ince Can, Groeneveld A. B. Johan Correction: Dose and type of crystalloid fluid therapy in adult hospitalized patients Perioperative medicine (London, England) 2014;3:3 [PubMed]
  • Veenstra G., Ince C., Boerma E. C. Direct markers of organ perfusion to guide fluid therapy: when to start, when to stop Best practice & research. Clinical anaesthesiology 2014;28 (3):217-226 [PubMed]
  • Kanoore Edul Vanina Siham, Ince Can, Navarro Noelia, Previgliano Luciana, Risso-Vazquez Alejandro, Rubatto Paolo Nahuel, Dubin Arnaldo Dissociation between sublingual and gut microcirculation in the response to a fluid challenge in postoperative patients with abdominal sepsis Annals of intensive care 2014;4:39 [PubMed]
  • Buijs Erik A. B., Verboom Elyse M., Top Anke P. C., Andrinopoulou Eleni-Rosalina, Buysse Corinne M. P., Ince Can, Tibboel Dick Early microcirculatory impairment during therapeutic hypothermia is associated with poor outcome in post-cardiac arrest children: a prospective observational cohort study Resuscitation 2014;85 (3):397-404 [PubMed]
  • Siervo Mario, Riley Heather L., Fernandez Bernadette O., Leckstrom Carl A., Martin Daniel S., Mitchell Kay, Levett Denny Z. H., Montgomery Hugh E., Mythen Monty G., Grocott Michael P. W., Feelisch Martin, Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H. Effects of Prolonged Exposure to Hypobaric Hypoxia on Oxidative Stress, Inflammation and Gluco-Insular Regulation: The Not-So-Sweet Price for Good Regulation PLoS ONE 2014;9 (4):e94915 [PubMed]
  • Buijs Erik A. B., Reiss Irwin K. M., Kraemer Ulrike, Andrinopoulou Eleni-Rosalina, Zwiers Alexandra J. M., Ince Can, Tibboel Dick Increasing mean arterial blood pressure and heart rate with catecholaminergic drugs does not improve the microcirculation in children with congenital diaphragmatic hernia: a prospective cohort study Pediatric critical care medicine 2014;15 (4):343-354 [PubMed]
  • Zarbock Alexander, Eroglu Ahmet, Erturk Engin, Ince Can, Westphal Martin Ischemia-Reperfusion Injury and Anesthesia BioMed research international 2014;2014:980318 [PubMed]
  • Vellinga Namkje Anna Rigtje Microcirculatory dysfunction in critically ill patients: prevalence and significance from a bedside perspective 2014. 181p. ISBN 9789462593022. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisor: Boerma E. C.)
  • Donati Abele, Damiani Elisa, Luchetti Michele, Domizi Roberta, Scorcella Claudia, Carsetti Andrea, Gabbanelli Vincenzo, Carletti Paola, Bencivenga Rosella, Vink Hans, Adrario Erica, Piagnerelli Michael, Gabrielli Armando, Pelaia Paolo, Ince Can Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in patients with sepsis: a pilot study Critical care (London, England) 2014;18 (1):R33 [PubMed]
  • van Zijderveld Rogier, Ince Can, Schlingemann Reinier O. Orthogonal polarization spectral imaging of conjunctival microcirculation Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2014;252 (5):773-779 [PubMed]
  • Murray Patrick T., Mehta Ravindra L., Shaw Andrew, Ronco Claudio, Endre Zoltan, Kellum John A., Chawla Lakhmir S., Cruz Dinna, Ince Can, Okusa Mark D., Murray Patrick, Kellum John, Chawla Lakhmir, Okusa Mark, Haase Michael, McCullough Peter, Bouchard Josee, Waikar Sus, Siew Eddie, Goldstein Stuart, Koyner Jay, Macedo Etienne, Doi Kent, Di Somma Salvatore, Maisel Alan, Lewington Andy, Thadhani Ravi, Bagshaw Sean, Chakravarthi Raj, Duranteau Jacques, Doran Peter, Yang Li, Jaber Bertrand, Clopton Paul, Bonventre Joe, Cutter Gary, Molitoris Bruce, Devarajan Prasad, Fitzgibbon Maria, Noiri Eisei, Parikh Chirag Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference Kidney international 2014;85 (3):513-521 [PubMed]
  • Almac Emre, Bezemer Rick, Hilarius-Stokman Petra M., Goedhart Peter, de Korte Dirk, Verhoeven Arthur J., Ince Can Red blood cell storage increases hypoxia-induced nitric oxide bioavailability and methemoglobin formation in vitro and in vivo Transfusion 2014;54 (12):3178-3185 [PubMed]
  • Ince Can, Groeneveld A. B. Johan The case for 0.9% NaCl: is the undefendable, defensible? Kidney international 2014;86 (6):1087-1095 [PubMed]
  • Ince Can The central role of renal microcirculatory dysfunction in the pathogenesis of acute kidney injury Nephron. Clinical practice 2014;127 (1-4):124-128 [PubMed]
  • Almac Emre Therapeutic strategies for the protection of renal oxygenation in experimental models of acute kidney injury 2014. 156p. ISBN 9789090285023. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisors: Bezemer R., van Iterson M.)
  • Ince Can The rationale for microcirculatory guided fluid therapy Current opinion in critical care 2014;20 (3):301-308 [PubMed]
  • Zafrani Lara, Ince Can The traumatic microcirculation Critical care medicine 2014;42 (6):1556-1557 [PubMed]
  • Chawla L. S., Ince C., Chappell D., Gan T. J., Kellum J. A., Mythen M., Shaw A. D. Vascular content, tone, integrity, and haemodynamics for guiding fluid therapy: a conceptual approach British journal of anaesthesia 2014;113 (5):748-755 [PubMed]
  • Hernandez Glenn, Luengo Cecilia, Bruhn Alejandro, Kattan Eduardo, Friedman Gilberto, Ospina-Tascon Gustavo A., Fuentealba Andrea, Castro Ricardo, Regueira Tomas, Romero Carlos, Ince Can, Bakker Jan When to stop septic shock resuscitation: clues from a dynamic perfusion monitoring Annals of intensive care 2014;4:30 [PubMed]

2013

  • Hernández Poblete Glenn W. A holistic approach for perfusion assessment in septic shock. Basic foundations and clinical applications 2013. 197p. ISBN 9789461823298. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Ince C., Bakker J.; Co-supervisor: Bezemer R.)
  • Donati Abele, Damiani Elisa, Domizi Roberta, Romano Rocco, Adrario Erica, Pelaia Paolo, Ince Can, Singer Mervyn Alteration of the sublingual microvascular glycocalyx in critically ill patients Microvascular research 2013;90:86-89 [PubMed]
  • Milstein Dan M. J., Cheung Yuk Wah, Žiūkaitė Laura, Ince Can, van den Akker Hans P., Lindeboom Jérôme A. H. An integrative approach for comparing microcirculation between normal and alveolar cleft gingiva in children scheduled for secondary bone grafting procedures Oral surgery, oral medicine, oral pathology and oral radiology 2013;115 (3):304-309 [PubMed]
  • Tytgat Stefaan H. A. J., van der Zee David C., Ince Can, Milstein Dan M. J. Carbon dioxide gas pneumoperitoneum induces minimal microcirculatory changes in neonates during laparoscopic pyloromyotomy Surgical endoscopy 2013;27 (9):3465-3473 [PubMed]
  • Wilson Mark H., Davagnanam Indran, Holland Graeme, Dattani Raj S., Tamm Alexander, Hirani Shashivadan P., Kolfschoten Nicky, Strycharczuk Lisa, Green Cathy, Thornton John S., Wright Alex, Edsell Mark, Kitchen Neil D., Sharp David J., Ham Timothy E., Murray Andrew, Holloway Cameron J., Clarke Kieran, Grocott Mike P. W., Montgomery Hugh, Imray Chris, Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J. Cerebral venous system and anatomical predisposition to high-altitude headache Annals of neurology 2013;73 (3):381-389 [PubMed]
  • Lupp Corinna, Baasner Silke, Ince Can, Nocken Frank, Stover John F., Westphal Martin Differentiated control of deranged nitric oxide metabolism: a therapeutic option in sepsis? Critical care (London, England) 2013;17 (3):311 [PubMed]
  • Smorenberg Annemieke, Ince Can, Groeneveld A. B. Johan Dose and type of crystalloid fluid therapy in adult hospitalized patients Perioperative medicine (London, England) 2013;2 (1):17 [PubMed]
  • Hernandez Glenn, Bruhn Alejandro, Luengo Cecilia, Regueira Tomas, Kattan Eduardo, Fuentealba Andrea, Florez Jorge, Castro Ricardo, Aquevedo Andres, Pairumani Ronald, McNab Paul, Ince Can Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study Intensive care medicine 2013;39 (8):1435-1443 [PubMed]
  • Vellinga Namkje A. R., Ince C., Boerma E. C. Elevated central venous pressure is associated with impairment of microcirculatory blood flow in sepsis: a hypothesis generating post hoc analysis Anesthesiology 2013;13 (1):17 [PubMed]
  • Donati Abele, Domizi Roberta, Damiani Elisa, Adrario Erica, Pelaia Paolo, Ince Can From Macrohemodynamic to the Microcirculation Critical care research and practice 2013;2013:892710 [PubMed]
  • Evans Roger G., Ince Can, Joles Jaap A., Smith David W., May Clive N., O'Connor Paul M., Gardiner Bruce S. Haemodynamic influences on kidney oxygenation: clinical implications of integrative physiology Clinical and experimental pharmacology & physiology 2013;40 (2):106-122 [PubMed]
  • Driessen Caroline, Plomp Raul G., van der Spek Peter J., Ince Can, Kulik Wim, Mathijssen Irene M. J., Joosten Koen F. M. Is there an effect of obstructive sleep apnea syndrome on oxidative stress and inflammatory parameters in patients with craniofacial anomalies? Journal of craniofacial surgery 2013;24 (6):1908-1913 [PubMed]
  • Klijn Eva, Hulscher Hester C., Balvers Rutger K., Holland Wim P. J., Bakker Jan, Vincent Arnaud J. P. E., Dirven Clemens M. F., Ince Can Laser speckle imaging identification of increases in cortical microcirculatory blood flow induced by motor activity during awake craniotomy Journal of neurosurgery 2013;118 (2):280-286 [PubMed]
  • Hernandez Glenn, Bruhn Alejandro, Ince Can Microcirculation in sepsis: new perspectives Current vascular pharmacology 2013;11 (2):161-169 [PubMed]
  • Zafrani Lara, Ince Can, Yuen Peter S. T. Microparticles during sepsis: target, canary or cure? Intensive care medicine 2013;39 (10):1854-1856 [PubMed]
  • Ruiz Carolina, Hernandez Glenn, Andresen Max, Ince Can, Bruhn Alejandro Mini-report: Microcirculatory flow abnormalities in a patient with severe hyperviscosity syndrome Clinical hemorheology and microcirculation 2013;54 (1):33-38 [PubMed]
  • Ashruf Jesse F., Bruining Hajo A., Ince Can New insights into the pathophysiology of cardiogenic shock: the role of the microcirculation Current opinion in critical care 2013;19 (5):381-386 [PubMed]
  • Marini John J., Vincent Jean-Louis, Wischmeyer Paul, Singer Mervyn, Gattinoni Luciano, Ince Can, Gan Tong Joo Our favorite unproven ideas for future critical care Critical care (London, England) 2013;17 (Suppl. 1):S9 [PubMed]
  • van Genderen Michel E., Bartels Sebastiaan A., Lima Alexandre, Bezemer Rick, Ince Can, Bakker Jan, van Bommel Jasper Peripheral perfusion index as an early predictor for central hypovolemia in awake healthy volunteers Anesthesia and analgesia 2013;116 (2):351-356 [PubMed]
  • Okusa Mark D., Jaber Bertrand L., Doran Peter, Duranteau Jacques, Yang Li, Murray Patrick T., Mehta Ravindra L., Ince Can Physiological biomarkers of acute kidney injury: a conceptual approach to improving outcomes Contributions to nephrology 2013;182:65-81 [PubMed]
  • Meybohm Patrick, van Aken Hugo, de Gasperi Andrea, de Hert Stefan, Della Rocca Giorgio, Girbes Armand R. J., Gombotz Hans, Guidet Bertrand, Hasibeder Walter, Hollmann Markus W., Ince Can, Jacob Matthias, Kranke Peter, Kozek-Langenecker Sibylle, Loer Stephan Alexander, Martin Claude, Siegemund Martin, Wunder Christian, Zacharowski Kai Re-evaluating currently available data and suggestions for planning randomised controlled studies regarding the use of hydroxyethyl starch in critically ill patients - a multidisciplinary statement Critical care (London, England) 2013;17 (4):R166 [PubMed]
  • Hernandez Glenn, Boerma E. Christiaan, Dubin Arnaldo, Bruhn Alejandro, Koopmans Matty, Edul Vanina Kanoore, Ruiz Carolina, Castro Ricardo, Pozo Mario Omar, Pedreros Cesar, Veas Enrique, Fuentealba Andrea, Kattan Eduardo, Rovegno Maximiliano, Ince Can Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients Journal of critical care 2013;28 (4):538.e9-538.14 [PubMed]
  • Donati Abele, Damiani Elisa, Botticelli Laura, Adrario Erica, Lombrano Maria Rita, Domizi Roberta, Marini Benedetto, van Teeffelen Jurgen W. G. E., Carletti Paola, Girardis Massimo, Pelaia Paolo, Ince Can The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome BMC anesthesiology 2013;13 (1):25 [PubMed]
  • Ayhan Banu, Yuruk Koray, Koene Sophia, Sahin Altan, Ince Can, Aypar Ulku The effects of non-leukoreduced red blood cell transfusions on microcirculation in mixed surgical patients Transfusion and apheresis science : official journal of the World Apheresis Association 2013;49 (2):212-222 [PubMed]
  • Ince Can The great fluid debate: when will physiology prevail? Anesthesiology 2013;119 (2):248-249 [PubMed]
  • Donati Abele, Tibboel Dick, Ince Can Towards integrative physiological monitoring of the critically ill: from cardiovascular to microcirculatory and cellular function monitoring at the bedside Critical care (London, England) 2013;17 (Suppl. 1):S5 [PubMed]
  • Yürük Koray, Milstein Dan M. J., Bezemer Rick, Bartels Sebastiaan A., Biemond Bart J., Ince Can Transfusion of banked red blood cells and the effects on hemorrheology and microvascular hemodynamics in anemic hematology outpatients Transfusion 2013;53 (6):1346-1352 [PubMed]

2012

  • Aksu Ugur, Bezemer Rick, Demirci Cihan, Ince Can ACUTE EFFECTS OF BALANCED VERSUS UNBALANCED COLLOID RESUSCITATION ON RENAL MACROCIRCULATORY AND MICROCIRCULATORY PERFUSION DURING ENDOTOXEMIC SHOCK Shock (Augusta, Ga.) 2012;37 (2):205-209 [PubMed]
  • Aksu Ugur, Bezemer R., Yavuz B., Kandil Asli, Demirci C., Ince C. Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress and inflammation Resuscitation 2012;83 (6):767-773 [PubMed]
  • Ince Can, van Kuijen Anne-Marije, Milstein Dan M. J., Yürük Koray, Folkow Lars P., Fokkens Wytske J., Blix Arnoldus S. CHRISTMAS 2012: RESEARCH Why Rudolph's nose is red: observational study BMJ (Clinical research ed.) 2012;345:e8311 [PubMed]
  • Vincent Jean-Louis, Ince Can, Bakker Jan Clinical review: Circulatory shock--an update: a tribute to Professor Max Harry Weil Critical care (London, England) 2012;16 (6):239 [PubMed]
  • Bezemer Rick, Bartels Sebastiaan A., Bakker Jan, Ince Can Clinical review: Clinical imaging of the sublingual microcirculation in the critically ill--where do we stand? Critical care (London, England) 2012;16 (3):224 [PubMed]
  • McMorrow R. C. N., Windsor J. S., Hart N. D., Richards P., Rodway G. W., Ahuja V. Y., O'Dwyer M. J., Mythen M. G., Grocott M. P. W., Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H., Morgan G., Morgan J. Closed and open breathing circuit function in healthy volunteers during exercise at Mount Everest base camp (5300 m) Anaesthesia 2012;67 (8):875-880 [PubMed]
  • Zacharowski Kai, van Aken H., Marx Gernot, Jacob Matthias, Schaffartzik Walter, Zenz Michael, Loer S. A., Ince Can, Martin Claude, de Hert Stefan, Hollmann Markus W., Girbes Armand R. J., Kozek-Langenecker Sybille, Gombotz Hans, Guidet Bertrand, Della Rocca Giorgio, Wilson Jonathan, de Gasperi Andrea Comments on Reinhart et al.: consensus statement of the ESICM task force on colloid volume therapy in critically ill patients Intensive care medicine 2012;38 (9):1556-1557 [PubMed]
  • Pozo Mario O., Kanoore Edul Vanina S., Ince Can, Dubin Arnaldo Comparison of different methods for the calculation of the microvascular flow index Critical care research and practice 2012;2012:102483 [PubMed]
  • Özarslan Nihal Gökbulut, Ayhan Banu, Kanbak Meral, Çelebioğlu Bilge, Demircin Metin, Ince Can, Aypar Ülkü Comparison of the Effects of Sevoflurane, Isoflurane, and Desflurane on Microcirculation in Coronary Artery Bypass Graft Surgery Journal of cardiothoracic and vascular anesthesia 2012;26 (5):791-798 [PubMed]
  • Elbers Paul W. G., Prins Wilhelmina B., Plokker Herbert W. M., van Dongen Eric P. A., van Iterson Mat, Ince Can Electrical Cardioversion for Atrial Fibrillation Improves Microvascular Flow Independent of Blood Pressure Changes Journal of cardiothoracic and vascular anesthesia 2012;26 (5):799-803 [PubMed]
  • Hernandez Glenn, Pedreros Cesar, Veas Enrique, Bruhn Alejandro, Romero Carlos, Rovegno Maximiliano, Neira Rodolfo, Bravo Sebastian, Castro Ricardo, Kattan Eduardo, Ince Can Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study Journal of critical care 2012;27 (3):283-288 [PubMed]
  • van Iterson Mat Functional heterogeneity of oxygen supply with blood and hemoglobin-based oxygen carriers in porcine models of hemorrhagic shockAmsterdam: Lecturis Eindhoven; 2012. 165p. ISBN 9789070108793. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisors: Bezemer R., van Dongen H. P. A.)
  • Piagnerelli Michael, Ince Can, Dubin Arnaldo Microcirculation Critical care research and practice 2012;2012:867176 [PubMed]
  • van Iterson Mat, Bezemer Rick, Heger Michal, Siegemund Martin, Ince Can Microcirculation follows macrocirculation in heart and gut in the acute phase of hemorrhagic shock and isovolemic autologous whole blood resuscitation in pigs Transfusion 2012;52 (7):1552-1559 [PubMed]
  • Milstein Dan M. J., van Kuijen Anne-Marije, Copper Marcel P., Karakullukçu Barış, Tan I. Bing, Lindeboom Jérôme A. H., Fokkens Wytske J., Ince Can Monitoring microcirculatory alterations in oral squamous cell carcinoma following photodynamic therapy Photodiagnosis and photodynamic therapy 2012;9 (1):69-75 [PubMed]
  • Hernandez Glenn, Bruhn Alejandro, Castro Ricardo, Pedreros Cesar, Rovegno Maximiliano, Kattan Eduardo, Veas Enrique, Fuentealba Andrea, Regueira Tomas, Ruiz Carolina, Ince Can Persistent Sepsis-Induced Hypotension without Hyperlactatemia: A Distinct Clinical and Physiological Profile within the Spectrum of Septic Shock Critical care research and practice 2012;2012:536852 [PubMed]
  • Edul Vanina S. Kanoore, Enrico Carolina, Laviolle Bruno, Vazquez Alejandro Risso, Ince Can, Dubin Arnaldo Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock Critical care medicine 2012;40 (5):1443-1448 [PubMed]
  • Bezemer Rick, Dobbe Johannes G., Bartels Sebastiaan A., Boerma E. Christiaan, Elbers Paul W. G., Heger Michal, Ince Can Rapid automatic assessment of microvascular density in sidestream dark field images (vol 49, pg 1269, 2011) Medical & biological engineering & computing 2012;50 (10):1115 [PubMed]
  • Atasever Bektaş, van der Kuil Marjolein, Boer Christa, Vonk Alexander, Schwarte Lothar, Girbes Armand R. J., Ince Can, Beishuizen Albertus, Groeneveld A. B. Johan Red blood cell transfusion compared with gelatin solution and no infusion after cardiac surgery: effect on microvascular perfusion, vascular density, hemoglobin, and oxygen saturation Transfusion 2012;52 (11):2452-2458 [PubMed]
  • Yuruk Koray, Bartels Sebastiaan A., Milstein Dan M. J., Bezemer Rick, Biemond Bart J., Ince Can Red blood cell transfusions and tissue oxygenation in anemic hematology outpatients Transfusion 2012;52 (3):641-646 [PubMed]
  • Smeele Kirsten M., Eerbeek Otto, Schaart Gert, Koeman Anneke, Bezemer Rick, Nelson Jessica K., Ince Can, Nederlof Rianne, Boek Maxim, Laakso Markku, de Haan Arnold, Drost Maarten R., Hollmann Markus W., Zuurbier Coert J. Reduced hexokinase II impairs muscle function 2 wk after ischemia-reperfusion through increased cell necrosis and fibrosis Journal of applied physiology (Bethesda, Md. 2012;113 (4):608-618 [PubMed]
  • Hernandez Glenn, Regueira Tomas, Bruhn Alejandro, Castro Ricardo, Rovegno Maximiliano, Fuentealba Andrea, Veas Enrique, Berrutti Dolores, Kattan Eduardo, Martin Celeste, Ince Can Relationship of systemic, hepatosplanchnic, and microcirculatory perfusion parameters with 6-hour lactate clearance in hyperdynamic septic shock patients: an acute, clinical-physiological, pilot study Annals of intensive care 2012;2 (1):44 [PubMed]
  • Aksu Ugur, Bezemer Rick, Ince Can Reply to: crystalloid resuscitation in hemorrhagic shock Resuscitation 2012;83 (8):E173 [PubMed]
  • Vellinga Namkje A. R., Boerma E. Christiaan, Koopmans Matty, Donati Abele, Dubin Arnaldo, Shapiro Nathan I., Pearse Rupert M., Bakker Jan, Ince Can Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients Critical care research and practice 2012;2012:121752 [PubMed]
  • Enrico Carolina, Kanoore Edul Vanina S., Vazquez Alejandro Risso, Pein María C., Pérez de la Hoz Ricardo A., Ince Can, Dubin Arnaldo Systemic and microcirculatory effects of dobutamine in patients with septic shock Journal of critical care 2012;27 (6):630-638 [PubMed]
  • Yuruk Koray, Bezemer Rick, Ince Can The ability of red blood cell transfusions to reach the microcirculationin: Jean-Louis Vincent, editors. Annual Update in Intensive Care and Emergency Medicine 2012. Berlin: Springer; 2012. p. 431-441, ISBN 9783642257155
  • Almac Emre, Aksu Ugur, Bezemer Rick, Jong Willeke, Kandil Asli, Yuruk Koray, Demirci-Tansel Cihan, Ince Can The acute effects of acetate-balanced colloid and crystalloid resuscitation on renal oxygenation in a rat model of hemorrhagic shock Resuscitation 2012;83 (9):1166-1172 [PubMed]
  • Yuruk Koray, Bezemer Rick, Euser Mariska, Milstein Dan M. J., de Geus Hilde H. R., Scholten Evert W., de Mol Bas A. J. M., Ince Can The effects of conventional extracorporeal circulation versus miniaturized extracorporeal circulation on microcirculation during cardiopulmonary bypass-assisted coronary artery bypass graft surgery Interactive cardiovascular and thoracic surgery 2012;15 (3):364-370 [PubMed]
  • Top Anke P. C., Buijs Erik A. B., Schouwenberg Patrick H. M., van Dijk Monique, Tibboel Dick, Ince Can The Microcirculation Is Unchanged in Neonates with Severe Respiratory Failure after the Initiation of ECMO Treatment Critical care research and practice 2012;2012:372956 [PubMed]
  • Atasever Bektaş The microcirculatory response during cardiac surgeryAmsterdam: PGVO/Ponsen & Looijen; 2012. 119p. ISBN 9789081895309. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Ince C., de Mol B. A. J. M.; Co-supervisor: Boer C.)
  • Legrand Matthieu, Bezemer Rick, Ince Can The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats: reply to Ji et al Intensive care medicine 2012;38 (2):336 [PubMed]

2011

  • McMorrow R. C. N., Windsor J. S., Mythen M. G., Grocott M. P. W., Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H., Morgan G., Morgan J., Murray A., Mythen M., Newman S., O'Dwyer M., Pate J. A novel ambulatory closed circuit breathing system for use during exercise Anaesthesia 2011;66 (5):348-353 [PubMed]
  • Yuruk Koray, Almac Emre, Bezemer Rick, Goedhart Peter, de Mol Bas, Ince Can Blood transfusions recruit the microcirculation during cardiac surgery Transfusion 2011;51 (5):961-967 [PubMed]
  • Atasever Bektas, Boer Christa, Speekenbrink Ron, Seyffert Jan, Goedhart Peter, de Mol Bas, Ince Can Cardiac displacement during off-pump coronary artery bypass grafting surgery: effect on sublingual microcirculation and cerebral oxygenation Interactive cardiovascular and thoracic surgery 2011;13 (6):573-577 [PubMed]
  • Holloway Cameron J., Montgomery Hugh E., Murray Andrew J., Cochlin Lowri E., Codreanu Ion, Hopwood Naomi, Johnson Andrew W., Rider Oliver J., Levett Denny Z. H., Tyler Damian J., Francis Jane M., Neubauer Stefan, Grocott Michael P. W., Clarke Kieran, Grocott Mike, Montgomery Hugh, Levett Denny, Martin Daniel, Wilson Mark, Windsor Jeremy, Luery Helen, Murray Andrew, Stroud Mike, Khosravi Maryam, Wandrag Liesl, Holloway Cameron, Edwards Lindsay, Ince Can, Mythen Monty, Jonas Max, Imray Chris, Newman Stan, Stygal Jan, Doyle Patrick, Rodway George, Howard David, McMorrow Roger, Ahuja Vijay, Aref-Adib Golnar, Burnham Richard Dick, Chisholm Amber, Coates David, Cook Debbie, Dhillon Sundeep, Dougall Christina, Duncan Polly, Edsell Mark, Evans Lynn, Gardiner Paul Bugs, Gunning Paul Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp FASEB journal 2011;25 (2):792-796 [PubMed]
  • Wilson Mark H., Edsell Mark E. G., Davagnanam Indran, Hirani Shashivadan P., Martin Dan S., Levett Denny Z. H., Thornton John S., Golay Xavier, Strycharczuk Lisa, Newman Stanton P., Montgomery Hugh E., Grocott Mike P. W., Imray Christopher H. E., Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P. Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia--an ultrasound and MRI study Journal of cerebral blood flow and metabolism 2011;31 (10):2019-2029 [PubMed]
  • Pérez-Bárcena Jon, Goedhart Peter, Ibáñez Javier, Brell Marta, García Roser, Llinás Pedro, Jiménez Carmen, Ince Can Direct observation of human microcirculation during decompressive craniectomy after stroke Critical care medicine 2011;39 (5):1126-1129 [PubMed]
  • Elbers Paul W. G., Wijbenga Jeroen, Solinger Frank, Yilmaz Aladdin, van Iterson Mat, van Dongen Eric P. A., Ince Can Direct observation of the human microcirculation during cardiopulmonary bypass: effects of pulsatile perfusion Journal of cardiothoracic and vascular anesthesia 2011;25 (2):250-255 [PubMed]
  • Atasever Bektaş, Boer Christa, Goedhart Peter, Biervliet Jules, Seyffert Jan, Speekenbrink Ron, Schwarte Lothar, de Mol Bas, Ince Can Distinct alterations in sublingual microcirculatory blood flow and hemoglobin oxygenation in on-pump and off-pump coronary artery bypass graft surgery Journal of cardiothoracic and vascular anesthesia 2011;25 (5):784-790 [PubMed]
  • Legrand Matthieu, Kandil Asli, Payen Didier, Ince Can Effects of sepiapterin infusion on renal oxygenation and early acute renal injury after suprarenal aortic clamping in rats Journal of cardiovascular pharmacology 2011;58 (2):192-198 [PubMed]
  • Johannes Tanja Experimental strategies in the treatment of acute renal failure in sepsis 2011. 112p. ISBN 9789461081377. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.)
  • Edul Vanina S. Kanoore, Ferrara Gonzalo, Pozo Mario O., Murias Gastón, Martins Enrique, Canullén Carlos, Canales Héctor S., Estenssoro Elisa, Ince Can, Dubin Arnaldo Failure of nitroglycerin (glyceryl trinitrate) to improve villi hypoperfusion in endotoxaemic shock in sheep Critical care and resuscitation 2011;13 (4):252-261 [PubMed]
  • Top Anke P. C., Ince Can, Schouwenberg Patrick H. M., Tibboel Dick Inhaled nitric oxide improves systemic microcirculation in infants with hypoxemic respiratory failure Pediatric critical care medicine 2011;12 (6):e271-e274 [PubMed]
  • Mik Egbert G. Measuring microvascular and mitochondrial oxygen tension. Novel techniques for studying tissue oxygeneration 2011. 157p. ISBN 9789461081360. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisor: Zuurbier C. J.)
  • Dyson Alex, Bezemer Rick, Legrand Matthieu, Balestra Gianmarco, Singer Mervyn, Ince Can Microvascular and interstitial oxygen tension in the renal cortex and medulla studied in a 4-h rat model of LPS-induced endotoxemia Shock (Augusta, Ga.) 2011;36 (1):83-89 [PubMed]
  • Mutalifu Yalikun, Holm Lovisa, Ince Can, Theodorsson Elvar, Sjöberg Folke Multiple different laminar velocity profiles in separate veins in the microvascular network of brain cortex in rats International journal of clinical and experimental medicine 2011;4 (1):10-16 [PubMed]
  • Bartels Sebastiaan A., Bezemer Rick, de Vries Floris J. Wallis, Milstein Dan M. J., Lima Alexandre, Cherpanath Thomas G. V., van den Meiracker Anton H., van Bommel Jasper, Heger Michal, Karemaker John M., Ince Can Multi-site and multi-depth near-infrared spectroscopy in a model of simulated (central) hypovolemia: lower body negative pressure Intensive care medicine 2011;37 (4):671-677 [PubMed]
  • Bartels Sebastiaan A., Stok Wim J., Bezemer Rick, Boksem Remco J., van Goudoever Jeroen, Cherpanath Thomas G. V., van Lieshout Johannes J., Westerhof Berend E., Karemaker John M., Ince Can Noninvasive cardiac output monitoring during exercise testing: Nexfin pulse contour analysis compared to an inert gas rebreathing method and respired gas analysis Journal of clinical monitoring and computing 2011;25 (5):315-321 [PubMed]
  • Bezemer Rick Optical methods for the assessment of microvascular perfusion and oxygenation 2011. 183p. ISBN 9789490371920. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisor: Heger M.)
  • Top Anke P. C., Ince Can, de Meij Neelke, van Dijk Monique, Tibboel Dick Persistent low microcirculatory vessel density in nonsurvivors of sepsis in pediatric intensive care Critical care medicine 2011;39 (1):8-13 [PubMed]
  • Atasever Bektaş, Boer Christa, van der Kuil Marjolein, Lust Eric, Beishuizen Albert, Speekenbrink Ron, Seyffert Jan, de Mol Bas, Ince Can Quantitative Imaging of Microcirculatory Response During Nitroglycerin-Induced Hypotension Journal of cardiothoracic and vascular anesthesia 2011;25 (1):140-144 [PubMed]
  • Bezemer Rick, Dobbe Johannes G., Bartels Sebastiaan A., Christiaan Boerma E., Elbers Paul W. G., Heger Michal, Ince Can Rapid automatic assessment of microvascular density in sidestream dark field images Medical & biological engineering & computing 2011;49 (11):1269-1278 [PubMed]
  • Boerma E. C., Kaiferová K., Konijn A. J. M., de Vries J. W., Buter H., Ince C. Rectal microcirculatory alterations after elective on-pump cardiac surgery Minerva anestesiologica 2011;77 (7):698-703 [PubMed]
  • Legrand Matthieu, Ince Can Role of sepiapterin on endothelial nitric oxide synthase in acute kidney injury: an enigmatic story Journal of cardiovascular pharmacology 2011;58 (3):335-336 [PubMed]
  • Khalilzada Mostafa, Dogan Kemal, Ince Can, Stam Jan Sublingual Microvascular Changes in Patients With Cerebral Small Vessel Disease Stroke; a journal of cerebral circulation 2011;42 (7):2071-2073 [PubMed]
  • Milstein Dan M. J., Lindeboom Jérôme A. H., Ince Can The influence of zoledronic acid and cyclophosphamide on microcirculation regeneration in healing oral mucosal flaps Archives of oral biology 2011;56 (6):599-606 [PubMed]
  • Kanoore Edul Vanina S., Dubin Arnaldo, Ince Can The microcirculation as a therapeutic target in the treatment of sepsis and shock Seminars in respiratory and critical care medicine 2011;32 (5):558-568 [PubMed]
  • Top Anke P. C., Tasker Robert C., Ince Can The microcirculation of the critically ill pediatric patient Critical care (London, England) 2011;15 (2):213 [PubMed]
  • Bartels Sebastiaan A., Bezemer Rick, Milstein Dan M. J., Radder Matthijs, Lima Alexandre, Cherpanath Thomas G. V., Heger Michal, Karemaker John M., Ince Can The microcirculatory response to compensated hypovolemia in a lower body negative pressure model Microvascular research 2011;82 (3):374-380 [PubMed]
  • Aksu Ugur, Demirci Cihan, Ince Can The Pathogenesis of Acute Kidney Injury and the Toxic Triangle of Oxygen, Reactive Oxygen Species and Nitric Oxide Contributions to nephrology 2011;174:119-128 [PubMed]
  • Lima Alexandre, van Bommel Jasper, Sikorska Karolina, van Genderen Michel, Klijn Eva, Lesaffre Emmanuel, Ince Can, Bakker Jan The relation of near-infrared spectroscopy with changes in peripheral circulation in critically ill patients Critical care medicine 2011;39 (7):1649-1654 [PubMed]
  • Dubin Arnaldo The relationship of CO2 metabolism to tissue perfusion, microcirculation, and treatment response in shock and sepsis 2011. 246p. ISBN 9789490371753. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.)
  • Levett Denny Z., Fernandez Bernadette O., Riley Heather L., Martin Daniel S., Mitchell Kay, Leckstrom Carl A., Ince Can, Whipp Brian J., Mythen Monty G., Montgomery Hugh E., Grocott Mike P., Feelisch Martin The role of nitrogen oxides in human adaptation to hypoxia Scientific reports 2011;1:109 [PubMed]
  • Legrand Matthieu, Bezemer Rick, Kandil Asli, Demirci Cihan, Payen Didier, Ince Can The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats Intensive care medicine 2011;37 (9):1534-1542 [PubMed]

2010

  • Siegemund Martin, van Bommel Jasper, Stegenga Michiel E., Studer Wolfgang, van Iterson Mat, Annaheim Sandra, Mebazaa Alexandre, Ince Can Aortic Cross-Clamping and Reperfusion in Pigs Reduces Microvascular Oxygenation by Altered Systemic and Regional Blood Flow Distribution Anesthesia and analgesia 2010;111 (2):345-353 [PubMed]
  • Boerma E. Christiaan, Ince Can Can normal be more normal than normal? Critical care medicine 2010;38 (2):738 [PubMed]
  • Grocott Michael P. W., Martin Daniel S., Wilson Mark H., Mitchell Kay, Dhillon Sundeep, Mythen Monty G., Montgomery Hugh E., Levett Denny Z. H., Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H., Morgan G., Morgan J., Murray A. Caudwell xtreme everest expedition High altitude medicine & biology 2010;11 (2):133-137 [PubMed]
  • Martin Daniel S., Goedhart Peter, Vercueil Andre, Ince Can, Levett Denny Z. H., Grocott Mike P. W. Changes in sublingual microcirculatory flow index and vessel density on ascent to altitude Experimental physiology 2010;95 (8):880-891 [PubMed]
  • Dubin A., Pozo M. O., Casabella C. A., Murias G., Palizas F., Moseinco M. C., Kanoore Edul V. S., Estenssoro E., Ince C. Comparison of 6% hydroxyethyl starch 130/0.4 and saline solution for resuscitation of the microcirculation during the early goal-directed therapy of septic patients Journal of critical care 2010;25 (4):659-659.e8 [PubMed]
  • Levett Denny Z. H., Martin Daniel S., Wilson Mark H., Mitchell Kay, Dhillon Sundeep, Rigat Fabio, Montgomery Hugh E., Mythen Monty G., Grocott Michael P. W., Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H., Morgan G., Morgan J. Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia BMC medical research methodology 2010;10:98 [PubMed]
  • Boerma E. Christiaan, Koopmans Matty, Konijn Arjan, Kaiferova Katerina, Bakker Andries J., van Roon Eric N., Buter Hanneke, Bruins Nienke, Egbers Peter H., Gerritsen Rik T., Koetsier Peter M., Kingma W. Peter, Kuiper Michael A., Ince Can Effects of nitroglycerin on sublingual microcirculatory blood flow in patients with severe sepsis/septic shock after a strict resuscitation protocol: A double-blind randomized placebo controlled trial Critical care medicine 2010;38 (1):93-100 [PubMed]
  • Bezemer Rick, Faber Dirk J., Almac Emre, Kalkman Jeroen, Legrand Matthieu, Heger Michal, Ince Can Evaluation of multi-exponential curve fitting analysis of oxygen-quenched phosphorescence decay traces for recovering microvascular oxygen tension histograms Medical & biological engineering & computing 2010;48 (12):1233-1242 [PubMed]
  • Legrand Matthieu, Mik Egbert G., Balestra Gianmarco M., Lutter Rene, Pirracchio Romain, Payen Didier, Ince Can Fluid Resuscitation Does Not Improve Renal Oxygenation during Hemorrhagic Shock in Rats Anesthesiology 2010;112 (1):119-127 [PubMed]
  • Elbers Paul W. G. Focus on flow. Imaging the human microcirculation in perioperative and intensive care medicine 2010. 154p. ISBN 9789490371388. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisor: van Dongen H. P. A.)
  • Top A. P. C., van Dijk M., van Velzen J. E., Ince C., Tibboel D. Functional Capillary Density Decreases after the First Week of Life in Term Neonates Neonatology 2010;99 (1):73-77 [PubMed]
  • Yapici Nihan, Ince Can Gastrointestinal complications and its predictors after cardiac surgery Turkish journal of gastroenterology 2010;21 (1):3-6 [PubMed]
  • Elbers Paul W. G., Craenen Antonius J., Driessen Antoine, Stehouwer Marco C., Munsterman Luuk, Prins Miranda, van Iterson Mat, Bruins Peter, Ince Can Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma Resuscitation 2010;81 (1):123-125 [PubMed]
  • Mutsaerts Henri J. M. M., Out Mattijs, Goedhart Peter T., Ince Can, Hardeman Max R., Romijn Johannes A., Rabelink Ton J., Reiber Johan H. C., Box Frieke M. A. Improved viscosity modeling in patients with type 2 diabetes mellitus by accounting for enhanced red blood cell aggregation tendency Clinical hemorheology and microcirculation 2010;44 (4):302-313 [PubMed]
  • Balestra Gianmarco M., Bezemer Rick, Boerma E. Christiaan, Yong Ze-Yie, Sjauw Krishan D., Engstrom Annemarie E., Koopmans Matty, Ince Can Improvement of Sidestream Dark Field Imaging with an Image Acquisition Stabilizer BMC medical imaging 2010;10 (1):15 [PubMed]
  • Milstein Dan M. J., Lindeboom Jérôme A. H., Ince Can Intravital sidestream dark-field (SDF) imaging is used in a rabbit model for continuous noninvasive monitoring and quantification of mucosal capillary regeneration during wound healing in the oral cavity: A pilot study Archives of oral biology 2010;55 (5):343-349 [PubMed]
  • Morelli Andrea, Donati Abele, Ertmer Christian, Rehberg Sebastian, Lange Matthias, Orecchioni Alessandra, Cecchini Valeria, Landoni Giovanni, Pelaia Paolo, Pietropaoli Paolo, van Aken Hugo, Teboul Jean-Louis, Ince Can, Westphal Martin Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study Critical care (London, England) 2010;14 (6):R232 [PubMed]
  • Vellinga Namkje A. R., Ince Can, Boerma E. Christiaan Microvascular dysfunction in the surgical patient Current opinion in critical care 2010;16 (4):377-383 [PubMed]
  • Elbers Paul W. G., Ozdemir Alaattin, Heijmen Robin H., Heeren Jos, van Iterson Mat, van Dongen Eric P. A., Ince Can Microvascular hemodynamics in human hypothermic circulatory arrest and selective antegrade cerebral perfusion Critical care medicine 2010;38 (7):1548-1553 [PubMed]
  • Smeele Kirsten M., Eerbeek Otto, Koeman Anneke, Bezemer Rick, Ince Can, Heikkinen Sami, Laakso Markku, de Haan Arnold, Schaart Gert, Drost Maarten R., Hollmann Markus W., Zuurbier Coert J. Partial hexokinase II knockout results in acute ischemia-reperfusion damage in skeletal muscle of male, but not female, mice Pflugers Archiv 2010;459 (5):705-712 [PubMed]
  • Bezemer Rick, Legrand Matthieu, Klijn Eva, Heger Michal, Post Ivo C. J. H., van Gulik Thomas M., Payen Didier, Ince Can Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging Optics express 2010;18 (14):15054-15061 [PubMed]
  • Edwards Lindsay M., Murray Andrew J., Tyler Damian J., Kemp Graham J., Holloway Cameron J., Robbins Peter A., Neubauer Stefan, Levett Denny, Montgomery Hugh E., Grocott Mike P., Clarke Kieran, Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H. The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition PLoS ONE 2010;5 (5):e10681 [PubMed]
  • Klijn Eva, Niehof Sjoerd, de Jonge Jeroen, Gommers Diederik, Ince Can, van Bommel Jasper The effect of perfusion pressure on gastric tissue blood flow in an experimental gastric tube model Anesthesia and analgesia 2010;110 (2):541-546 [PubMed]
  • Boldt Joachim, Ince Can The impact of fluid therapy on microcirculation and tissue oxygenation in hypovolemic patients: a review Intensive care medicine 2010;36 (8):1299-1308 [PubMed]
  • Legrand Matthieu, Klijn Eva, Payen Didier, Ince Can The response of the host microcirculation to bacterial sepsis: does the pathogen matter? Journal of molecular medicine (Berlin, Germany) 2010;88 (2):127-133 [PubMed]
  • Milstein Dan M. J. The response of the oral microcirculation to pharmacological and surgical interventions 2010. 145p. ISBN 9789490371449. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Ince C., van den Akker H. P.; Co-supervisor: Lindeboom J. A. H.)
  • Boerma E. Christiaan, Ince Can The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients Intensive care medicine 2010;36 (12):2004-2018 [PubMed]
  • Milstein Dan M. J., te Boome Liane C. J., Cheung Yuk Wah, Lindeboom Jérôme A. H., van den Akker Hans P., Biemond Bart J., Ince Can Use of sidestream dark-field (SDF) imaging for assessing the effects of high-dose melphalan and autologous stem cell transplantation on oral mucosal microcirculation in myeloma patients Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2010;109 (1):91-97 [PubMed]
  • Bezemer Rick, Klijn Eva, Khalilzada Mostafa, Lima Alexandre, Heger Michal, van Bommel Jasper, Ince Can Validation of near-infrared laser speckle imaging for assessing microvascular (re)perfusion Microvascular research 2010;79 (2):139-143 [PubMed]
  • Munsterman Luuk D. H., Elbers Paul W. G., Ozdemir Alaattin, van Dongen Eric P. A., van Iterson Mat, Ince Can Withdrawing intra-aortic balloon pump support paradoxically improves microvascular flow Critical care (London, England) 2010;14 (4):R161 [PubMed]

2009

  • Martin Daniel S., Ince Can, Goedhart Peter, Levett Denny Z. H., Grocott Mike P. W. Abnormal blood flow in the sublingual microcirculation at high altitude European journal of applied physiology 2009;106 (3):473-478 [PubMed]
  • Grocott Michael P. W., Martin Daniel S., Levett Denny Z. H., McMorrow Roger, Windsor Jeremy, Montgomery Hugh E., Ahuja V., Aref-Adib G., Burnham R., Chisholm A., Clarke K., Coates D., Coates M., Cook D., Cox M., Dhillon S., Dougall C., Doyle P., Duncan P., Edsell M., Edwards L., Evans L., Gardiner P., Grocott M., Gunning P., Hart N., Harrington J., Harvey J., Holloway C., Howard D., Hurlbut D., Imray C., Ince C., Jonas M., van der Kaaij J., Khosravi M., Kolfschoten N., Levett D., Luery H., Luks A., Martin D., McMorrow R., Meale P., Mitchell K., Montgomery H., Morgan G., Morgan J., Murray A., Mythen M., Newman S. Arterial blood gases and oxygen content in climbers on Mount Everest New England journal of medicine 2009;360 (2):140-149 [PubMed]
  • Bezemer Rick, Lima Alexandre, Myers Dean, Klijn Eva, Heger Michal, Goedhart Peter T., Bakker Jan, Ince Can Assessment of tissue oxygen saturation during a vascular occlusion test using near-infrared spectroscopy: the role of probe spacing and measurement site studied in healthy volunteers Critical care (London, England) 2009;13 (Suppl. 5):S4 [PubMed]
  • Top Anke P. C., Ince Can, van Dijk Monique, Tibboel Dick Changes in buccal microcirculation following extracorporeal membrane oxygenation in term neonates with severe respiratory failure Critical care medicine 2009;37 (3):1121-1124 [PubMed]
  • Bemelmans Remy H. H., Boerma E. Christiaan, Barendregt Jos, Ince Can, Rommes Johannes H., Spronk Peter E. Changes in the volume status of haemodialysis patients are reflected in sublingual microvascular perfusion Nephrology, dialysis, transplantation 2009;24 (11):3487-3492 [PubMed]
  • Gómez Hernando, Mesquida Jaume, Simon Peter, Kim Hyung Kook, Puyana Juan C., Ince Can, Pinsky Michael R. Characterization of tissue oxygen saturation and the vascular occlusion test: influence of measurement sites, probe sizes and deflation thresholds Critical care (London, England) 2009;13 (Suppl. 5):S3 [PubMed]
  • Boerma E. Christiaan Distributive failure in the microcirculation of septic patients 2009. 142p. ISBN 9789490122157. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Ince C.; Co-supervisors: van der Voort P. H. J., Kuiper M. A.)
  • Johannes Tanja, Mik Egbert G., Klingel Karin, Goedhart Peter T., Zanke Christof, Nohé Boris, Dieterich Hans-Jürgen, Unertl Klaus E., Ince Can Effects of 1400W and/or nitroglycerin on renal oxygenation and kidney function during endotoxaemia in anaesthetized rats Clinical and experimental pharmacology & physiology 2009;36 (9):870-879 [PubMed]
  • Johannes Tanja, Ince Can, Klingel Karin, Unertl Klaus E., Mik Egbert G. Iloprost preserves renal oxygenation and restores kidney function in endotoxemia-related acute renal failure in the rat Critical care medicine 2009;37 (4):1423-1432 [PubMed]
  • Lam Kayan, Sjauw Krischan D., Henriques José P. S., Ince Can, de Mol Bas A. J. M. Improved microcirculation in patients with an acute ST-elevation myocardial infarction treated with the Impella LP2.5 percutaneous left ventricular assist device Clinical research in cardiology 2009;98 (5):311-318 [PubMed]
  • Dubin Arnaldo, Pozo Mario O., Casabella Christian A., Palizas Fernando, Murias Gaston, Moseinco Miriam C., Kanoore Edul Vanina S., Estenssoro Elisa, Ince Can Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study Critical care (London, England) 2009;13 (3):R92 [PubMed]
  • den Uil Corstiaan A., Bezemer Rick, Miranda Dinis R., Ince Can, Lagrand Wim K., Hartman Michael, Bogers Ad J., Spronk Peter E., Simoons Maarten L. Intra-operative assessment of human pulmonary alveoli in vivo using Sidestream Dark Field imaging: a feasibility study Medical science monitor 2009;15 (10):MT137-MT141 [PubMed]
  • Legrand Matthieu, Almac Emre, Mik Egbert G., Johannes Tanja, Kandil Asli, Bezemer Rick, Payen Didier, Ince Can L-NIL prevents renal microvascular hypoxia and increase of renal oxygen consumption after ischemia-reperfusion in rats American journal of physiology. Renal physiology 2009;296 (5):F1109-F1117 [PubMed]
  • Johannes Tanja, Mik Egbert G., Klingel Karin, Dieterich Hans-Jürgen, Unertl Klaus E., Ince Can Low-dose dexamethasone-supplemented fluid resuscitation reverses endotoxin-induced acute renal failure and prevents cortical microvascular hypoxia Shock (Augusta, Ga.) 2009;31 (5):521-528 [PubMed]
  • den Uil Corstiaan A., Lagrand Wim K., Spronk Peter E., van der Ent Martin, Jewbali Lucia S. D., Brugts Jasper J., Ince Can, Simoons Maarten L. Low-dose nitroglycerin improves microcirculation in hospitalized patients with acute heart failure European journal of heart failure 2009;11 (4):386-390 [PubMed]
  • Lima Alexandre, van Bommel Jasper, Jansen Tim C., Ince Can, Bakker Jan Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients Critical care (London, England) 2009;13 (Suppl. 5):S13 [PubMed]
  • Balestra Gianmarco M., Legrand Matthieu, Ince Can Microcirculation and mitochondria in sepsis: getting out of breath Current opinion in anaesthesiology 2009;22 (2):184-190 [PubMed]
  • Elbers Paul W. G., Ozdemir Alaattin, van Iterson Mat, van Dongen Eric P. A., Ince Can Microcirculatory Imaging in Cardiac Anesthesia: Ketanserin Reduces Blood Pressure But Not Perfused Capillary Density Journal of cardiothoracic and vascular anesthesia 2009;23 (1):95-101 [PubMed]
  • Mik Egbert G., Ince Can, Eerbeek Otto, Heinen Andre, Stap Jan, Hooibrink Berend, Schumacher Cees A., Balestra Gianmarco M., Johannes Tanja, Beek Johan F., Nieuwenhuis Ab F., van Horssen Pepijn, Spaan Jos A., Zuurbier Coert J. Mitochondrial oxygen tension within the heart Journal of molecular and cellular cardiology 2009;46 (6):943-951 [PubMed]
  • Ince Can, Bezemer Rick, Lima Alex Near infrared spectroscopy Critical care medicine 2009;37 (1):384-385 [PubMed]
  • Johannes Tanja, Mik Egbert G., Ince Can Nonresuscitated endotoxemia induces microcirculatory hypoxic areas in the renal cortex in the rat Shock (Augusta, Ga.) 2009;31 (1):97-103 [PubMed]
  • Donati Abele, Romanelli Michela, Botticelli Laura, Valentini Agnese, Gabbanelli Vincenzo, Nataloni Simonetta, Principi Tiziana, Pelaia Paolo, Bezemer Rick, Ince Can Recombinant activated protein C treatment improves tissue perfusion and oxygenation in septic patients measured by near-infrared spectroscopy Critical care (London, England) 2009;13 (Suppl. 5):S12 [PubMed]
  • Raat Nicolaas J. H., Hilarius Petra M., Johannes Tanja, de Korte Dirk, Ince Can, Verhoeven Arthur J. Rejuvenation of stored human red blood cells reverses the renal microvascular oxygenation deficit in an isovolemic transfusion model in rats Transfusion 2009;49 (3):427-434 [PubMed]
  • Bezemer Rick, Karemaker John M., Klijn Eva, Martin Daniel, Mitchell Kay, Grocott Mike, Heger Michal, Ince Can Simultaneous multi-depth assessment of tissue oxygen saturation in thenar and forearm using near-infrared spectroscopy during a simple cardiovascular challenge Critical care (London, England) 2009;13 (Suppl. 5):S5 [PubMed]
  • Dubin Arnaldo, Pozo Mario Omar, Ferrara Gonzalo, Murias Gastón, Martins Enrique, Canullán Carlos, Canales Héctor Saul, Kanoore Edul Vanina Siham, Estenssoro Elisa, Ince Can Systemic and microcirculatory responses to progressive hemorrhage Intensive care medicine 2009;35 (3):556-564 [PubMed]
  • Milstein Dan M. J., Bezemer Rick, Lindeboom Jérôme A. H., Ince Can The acute effects of CMF-based chemotherapy on maxillary periodontal microcirculation Cancer chemotherapy and pharmacology 2009;64 (5):1047-1052 [PubMed]
  • Lima Alexandre, Jansen Tim C., van Bommel Jasper, Ince Can, Bakker Jan The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients Critical care medicine 2009;37 (3):934-938 [PubMed]
  • Le Dorze Matthieu, Legrand Matthieu, Payen Didier, Ince Can The role of the microcirculation in acute kidney injury Current opinion in critical care 2009;15 (6):503-508 [PubMed]
  • Milstein Dan M. J., Mathura Keshen R., Lindeboom Jerôme A. H., Ramsoekh Dewkoemar, Lindeboom Robert, Ince Can The temporal course of mucoperiosteal flap revascularization at guided bone regeneration-treated implant sites: a pilot study Journal of clinical periodontology 2009;36 (10):892-897 [PubMed]
  • Nieuwdorp M., Meuwese M. C., Mooij H. L., van Lieshout M. H. P., Hayden A., Levi M. [=Marcel M.], Meijers J. C. M., Ince C., Kastelein J. J. P., Vink H., Stroes E. S. G. Tumor necrosis factor-alpha inhibition protects against endotoxin-induced endothelial glycocalyx perturbation Atherosclerosis 2009;202 (1):296-303 [PubMed]

2008

  • Dondorp A. M., Ince C., Charunwatthana P., Hanson J., van Kuijen A., Faiz M. A., Rahman M. R., Hasan M., Bin Yunus E., Ghose A., Ruangveerayut R., Limmathurotsakul D., Mathura K., White N. J., Day N. P. J. Direct in vivo assessment of microcirculatory dysfunction in severe falciparum malaria Journal of infectious diseases 2008;197 (1):79-84 [PubMed]
  • Boerma E. Christiaan, Kuiper MichaelA., Kingma W. Peter, Egbers Peter H., Gerritsen Rik T., Ince Can Disparity between skin perfusion and sublingual microcirculatory alterations in severe sepsis and septic shock: a prospective observational study Intensive care medicine 2008;34 (7):1294-1298 [PubMed]
  • van Bommel Jasper, Siegemund Martin, Henny Ch. Pieter, Ince Can Heart, kidney, and intestine have different tolerances for anemia Translational research 2008;151 (2):110-117 [PubMed]
  • Mik Egbert G., Johannes Tanja, Zuurbier Coert J., Heinen Andre, Houben-Weerts Judith H. P. M., Balestra Gianmarco M., Stap Jan, Beek Johan F., Ince Can In vivo mitochondrial oxygen tension measured by a delayed fluorescence lifetime technique Biophysical journal 2008;95 (8):3977-3990 [PubMed]
  • Fries Michael, Ince Can, Rossaint Rolf, Bleilevens Christian, Bickenbach Johannes, Rex Steffen, Mik Egbert G. Levosimendan but not norepinephrine improves microvascular oxygenation during experimental septic shock Critical care medicine 2008;36 (6):1886-1891 [PubMed]
  • Dobbe J. G. G., Streekstra G. J., Atasever B., van Zijderveld R., Ince C. Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis Medical & biological engineering & computing 2008;46 (7):659-670 [PubMed]
  • Nieuwdorp Max, Meuwese Marijn C., Mooij Hans L., Ince Can, Broekhuizen Lysette N., Kastelein John J. P., Stroes Erik S. G., Vink Hans Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability Journal of applied physiology (Bethesda, Md. 2008;104 (3):845-852 [PubMed]
  • Lindeboom Jerome A., Mathura Keshen R., Milstein Dan M. J., Ince Can Microvascular soft tissue changes in alveolar distraction osteogenesis Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2008;106 (3):350-355 [PubMed]
  • Mik Egbert G., Johannes Tanja, Ince Can Monitoring of renal venous PO2 and kidney oxygen consumption in rats by a near-infrared phosphorescence lifetime technique American journal of physiology. Renal physiology 2008;294 (3):F676-F681 [PubMed]
  • van Beers Eduard J., Goedhart Peter T., Unger Michiel, Biemond Bart J., Ince Can Normal sublingual microcirculation during painful crisis in sickle cell disease Microvascular research 2008;76 (1):57-60 [PubMed]
  • Dubin Arnaldo, Edul Vanina Siham Kanoore, Pozo Mario Omar, Murias Gastón, Canullán Carlos Manuel, Martins Enrique Francisco, Ferrara Gonzalo, Canales Héctor Saul, Laporte Mercedes, Estenssoro Elisa, Ince Can Persistent villi hypoperfusion explains intramucosal acidosis in sheep endotoxemia Critical care medicine 2008;36 (2):535-542 [PubMed]
  • Legrand Matthieu, Mik Egbert G., Johannes Tanja, Payen Didier, Ince Can Renal hypoxia and dysoxia after reperfusion of the ischemic kidney Molecular medicine (Cambridge, Mass.) 2008;14 (7-8):502-516 [PubMed]
  • Ince Can The elusive microcirculation Intensive care medicine 2008;34 (10):1755-1756 [PubMed]
  • Klijn Eva, den Uil C. A., Bakker Jan, Ince Can The heterogeneity of the microcirculation in critical illness Clinics in chest medicine 2008;29 (4):643-654 [PubMed]
  • den Uil Corstian A., Klijn E., Lagrand W. K., Brugts J. J., Ince C., Spronk P. E., Simoons M. L. The microcirculation in health and critical disease Progress in cardiovascular diseases 2008;51 (2):161-170 [PubMed]

2007

  • Johannes Tanja, Mik Egbert G., Nohé Boris, Unertl Klaus E., Ince Can Acute decrease in renal microvascular PO2 during acute normovolemic hemodilution American journal of physiology. Renal physiology 2007;292 (2):F796-F803 [PubMed]
  • Spoelstra E. N., Ince C., Koeman A., Emons V. M., Brouwer L. A., van Luyn M. J. A., Westerink B. H. C., Remie R. A novel and simple method for endotracheal intubation of mice Laboratory animals 2007;41 (1):128-135 [PubMed]
  • Erol-Yilmaz Ayten, Atasever Bektas, Mathura Keshen, Lindeboom Jerome, Wilde Arthur, Ince Can, Tukkie Raymond Cardiac resynchronization improves microcirculation Journal of cardiac failure 2007;13 (2):95-99 [PubMed]
  • de Backer Daniel, Hollenberg Steven, Boerma Christiaan, Goedhart Peter, Büchele Gustavo, Ospina-Tascon Gustavo, Dobbe Iwan, Ince Can How to evaluate the microcirculation: report of a round table conference Critical care (London, England) 2007;11 (5):R101-9 [PubMed]
  • Lindeboom Jerome A. H., Mathura Keshen R., Aartman Irene H. A., Kroon Frans H. M., Milstein Dan M. J., Ince Can Influence of the application of platelet-enriched plasma in oral mucosal wound healing Clinical oral implants research 2007;18 (1):133-139 [PubMed]
  • Raat N. J. H., Ince C. Oxygenating the microcirculation: the perspective from blood transfusion and blood storage Vox sanguinis 2007;93 (1):12-18 [PubMed]
  • Boerma E. Christiaan, van der Voort Peter H. J., Spronk Peter E., Ince Can Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis Critical care medicine 2007;35 (4):1055-1060 [PubMed]
  • Jansen Gerard F. A., Krins Anne, Basnyat Buddha, Odoom Joseph A., Ince Can Role of the altitude level on cerebral autoregulation in residents at high altitude Journal of applied physiology (Bethesda, Md. 2007;103 (2):518-523 [PubMed]
  • Goedhart P. T., Khalilzada M., Bezemer R., Merza J., Ince C. Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation Optics express 2007;15 (23):15101-15114 [PubMed]
  • Pennings Fritz A. The clinical value of assessing cerebral ischemia : emphasis on brain tissue oxygenation and function of the cerebral microcirculation 2007. 112p. ISBN 9789051709322. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Bosch D. A., Ince C.; Co-supervisor: Bouma Gerrit J.)
  • Almac Emre, Ince Can The impact of storage on red cell function in blood transfusion Best practice & research. Clinical anaesthesiology 2007;21 (2):195-208 [PubMed]
  • Siegemund M., van Bommel J., Sinaasappel M., Schwarte L. A., Studer W., Girard T., Vollebregt K., Ince C. The NO donor SIN-1 improves intestinal-arterial P(CO(2)) gap in experimental endotoxemia: an animal study Acta anaesthesiologica Scandinavica 2007;51 (6):693-700 [PubMed]

2006

  • Pennings Frederik A., Ince Can, Bouma Gerrit J. Continuous real-time visualization of the human cerebral microcirculation during arteriovenous malformation surgery using orthogonal polarization spectral imaging Neurosurgery 2006;59 (1):167-71; discussion 167-71 [PubMed]
  • Johannes Tanja, Mik Egbert G., Ince Can Dual-wavelength phosphorimetry for determination of cortical and subcortical microvascular oxygenation in rat kidney Journal of applied physiology (Bethesda, Md. 2006;100 (4):1301-1310 [PubMed]
  • Nieuwdorp Max, Mooij Hans L., Kroon Jojanneke, Atasever Bektas, Spaan Jos A. E., Ince Can, Holleman Frits, Diamant Michaela, Heine Robert J., Hoekstra Joost B. L., Kastelein John J. P., Stroes Erik S. G., Vink Hans Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes Diabetes 2006;55 (4):1127-1132 [PubMed]
  • Ince Can Go with the flow--recruit the microcirculation! Intensive care medicine 2006;32 (4):488-489 [PubMed]
  • Johannes Tanja, Mik Egbert G., Nohé Boris, Raat Nicolaas J. H., Unertl Klaus E., Ince Can Influence of fluid resuscitation on renal microvascular PO2 in a normotensive rat model of endotoxemia Critical care (London, England) 2006;10 (3):R88 [PubMed]
  • Elbers Paul W. G., Ince Can Mechanisms of critical illness--classifying microcirculatory flow abnormalities in distributive shock Critical care (London, England) 2006;10 (4):221 [PubMed]
  • Almac E., Siegemund M., Demirci C., Ince C. Microcirculatory recruitment maneuvers correct tissue CO2 abnormalities in sepsis Minerva anestesiologica 2006;72 (6):507-519 [PubMed]
  • Mik Egbert G., Stap Jan, Sinaasappel Michiel, Beek Johan F., Aten Jacob A., van Leeuwen Ton G., Ince Can Mitochondrial PO2 measured by delayed fluorescence of endogenous protoporphyrin IX Nature methods 2006;3 (11):939-945 [PubMed]
  • van den Oever Huub L. A., Dzoljic Misa, Ince Can, Hollmann Markus W., Mokken Fleur C. Orthogonal polarization spectral imaging of the microcirculation during acute hypervolemic hemodilution and epidural lidocaine injection Anesthesia and analgesia 2006;103 (2):484-7, table of contents [PubMed]
  • Lindeboom Jerome A., Mathura Keshen R., Ince Can Orthogonal polarization spectral (OPS) imaging and topographical characteristics of oral squamous cell carcinoma Oral oncology 2006;42 (6):581-585 [PubMed]
  • Lindeboom J. A., Mathura K. R., Ramsoekh D., Harkisoen S., Aartman I. H., van den Akker H. P., Ince C. The assessment of the gingival capillary density with orthogonal spectral polarization (OPS) imaging Archives of oral biology 2006;51 (8):697-702 [PubMed]
  • Spronk Peter E., Rommes Johannes H., Schaar Cees, Ince Can Thrombolysis in fulminant purpura: observations on changes in microcirculatory perfusion during successful treatment Thrombosis and haemostasis 2006;95 (3):576-578 [PubMed]

2005

  • Heger Michal, Beek Johan, Stenback Karin, Faber Dirk, van Gemert Martin, Ince Can Darkfield orthogonal polarized spectral imaging for studying endovascular laser-tissue interactions in vivo - a preliminary study Optics express 2005;13 (3):702-715 [PubMed]
  • Lindeboom J. A., Mathura K. R., Harkisoen S., van den Akker H. P., Ince C. Effect of smoking on the gingival capillary density: assessment of gingival capillary density with orthogonal polarization spectral imaging Journal of clinical periodontology 2005;32 (12):1208-1212 [PubMed]
  • Raat Nicolaas J. H., Liu Jing-Feng, Doyle Michael P., Burhop Kenneth E., Klein Jan, Ince Can Effects of recombinant-hemoglobin solutions rHb2.0 and rHb1.1 on blood pressure, intestinal blood flow, and gut oxygenation in a rat model of hemorrhagic shock Journal of laboratory and clinical medicine 2005;145 (1):21-32 [PubMed]
  • Siegemund Martin, van Bommel Jasper, Schwarte Lothar A., Studer Wolfgang, Girard Thierry, Marsch Stephan, Radermacher Peter, Ince Can Inducible nitric oxide synthase inhibition improves intestinal microcirculatory oxygenation and CO2 balance during endotoxemia in pigs Intensive care medicine 2005;31 (7):985-992 [PubMed]
  • Spronk P. E., Kanoore-Edul V. S., Ince C. Microcirculatory and mitochondrial distress syndrome (MMDS): a new look at sepsisin: M. R. Pinsky, D. Payen, editors. Functional hemodynamic monitoring. Update in intensive care and emergency medicine. S.l.: Sringer; 2005., ISBN 9783540223498
  • Ince C. Microcirculatory distress in critically ill patients: meaning and futurein: M. P. Fink, P. M. Suter, W. J. Sibbald, editors. Update in intensive care and emergency medicine: intensive care medicine in 10 years. S.l.: Springer Verlag; 2005. p. 165-177, ISBN 1398735402609
  • Boerma E. Christiaan, Mathura Keshen R., van der Voort Peter H. J., Spronk Peter E., Ince Can Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study Critical care medicine 2005;9 (6):R601-R606 [PubMed]
  • Schwarte Lothar A., Fournell Artur, van Bommel Jasper, Ince Can Redistribution of intestinal microcirculatory oxygenation during acute hemodilution in pigs Journal of applied physiology (Bethesda, Md. 2005;98 (3):1070-1075 [PubMed]
  • Zuurbier Coert J., Demirci Cihan, Koeman Anneke, Vink Hans, Ince Can Short-term hyperglycemia increases endothelial glycocalyx permeability and acutely decreases lineal density of capillaries with flowing red blood cells Journal of applied physiology (Bethesda, Md. 2005;99 (4):1471-1476 [PubMed]
  • Milstein D. M. J., Lindeboom J. A. H., Ince C. Sidestream dark-field imaging and image analysis of oral microcirculation under clinical conditionsin: A. Gullo, editors. Anaesthesia pain IC and emergency. S.l.: s.n.; 2005. p. 79-88
  • Boerma E. C., van der Voort P. H. J., Ince C. Sublingual microcirculatory flow is impaired by the vasopressin-analogue terlipressin in a patient with catecholamine-resistant septic shock Acta anaesthesiologica Scandinavica 2005;49 (9):1387-1390 [PubMed]
  • Raat N. J. H., Berends F., Verhoeven A. J., de Korte D., Ince C. The age of stored red blood cell concentrates at the time of transfusion Transfusion medicine (Oxford, England) 2005;15 (5):419-423 [PubMed]
  • Buise Marc P., Ince Can, Tilanus Hugo W., Klein Jan, Gommers Diederik, van Bommel Jasper The effect of nitroglycerin on microvascular perfusion and oxygenation during gastric tube reconstruction Anesthesia and analgesia 2005;100 (4):1107-1111 [PubMed]
  • Raat N. J., Verhoeven A. J., Mik E. G., Gouwerok C. W., Verhaar R., Goedhart P. T., de Korte D., Ince C. The effect of storage time of human red cells on intestinal microcirculatory oxygenation in a rat isovolemic exchange model Critical care medicine 2005;33 (1):39-45 [PubMed]
  • Lindeboom J. A. H., Mathura K. R., Ince C. The microcirculation during wound healing after oral and maxillofacial surgical proceduresin: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2005. S.l.: Springer Verlag; 2005. p. 519-527
  • Ince Can The microcirculation is the motor of sepsis Critical care (London, England) 2005;9 (Suppl. 4):S13-S19 [PubMed]

2004

  • Ince C. Basic science for the cardiologistNorwell, Dordrecht: Kluwer Academic Publishers; 2004.
  • Spronk Peter E., Zandstra Durk F., Ince Can Bench-to-bedside review: Sepsis is a disease of the microcirculation Critical care (London, England) 2004;8 (6):462-468 [PubMed]
  • Pennings Frederik A., Bouma Gerrit J., Ince Can Direct observation of the human cerebral microcirculation during aneurysm surgery reveals increased arteriolar contractility Stroke; a journal of cerebral circulation 2004;35 (6):1284-1288 [PubMed]
  • Zuurbier C. J., Eerbeek O., Goedhart P. T., Struys E. A., Verhoeven N. M., Jakobs C., Ince C. Inhibition of the pentose phosphate pathway decreases ischemia-reperfusion-induced creatine kinase release in the heart Cardiovascular research 2004;62 (1):145-153 [PubMed]
  • van Zanten A. R., Schultz M. J., van der Voort P. H., Kuiper M. A., Ince C., Kesecioglu J. Klinisch geneesmiddelenonderzoek bij acuut beslissingsonbekwame patiënten in de neurologie en de neurochirurgie; implicaties van nieuwe Europese regelgeving Nederlands tijdschrift voor geneeskunde 2004;148 (5):246-247 [PubMed]
  • Schwarte L. A., Ince C. Mechanical ventilation in micein: C. Ince, editors. The physiological genomics of the critically ill mouse. Boston: Kluwer Academic Publishers; 2004. p. 35-53, ISBN 9781402076411
  • Ince Can Microcirculation in distress: A new resuscitation end point? Critical care medicine 2004;32 (9):1963-1964 [PubMed]
  • Zuurbier C. J., Emons V. M., Koeman A., Ince C. Mouse anesthesia in relation to optimal hemodynamicsin: C. Ince, editors. The physiological genomics of the critically ill mouse. Boston: Kluwer Academic Publishers; 2004. p. 23-34, ISBN 9781402076411
  • Spronk Peter E., Zandstra Durk F., Ince Can Norepinephrine compromises intestinal microvascular perfusion? Intensive care medicine 2004;30 (1):173-174 [PubMed]
  • de Mik E., Ince C. Optical spectroscopy in micein: C. Ince, editors. The physiological genomics of the critically ill mouse. Boston: Kluwer Academic Publishers; 2004. p. 73-89, ISBN 9781402076411
  • Mik Egbert G., van Leeuwen Ton G., Raat Nicolaas J., Ince Can Quantitative determination of localized tissue oxygen concentration in vivo by two-photon excitation phosphorescence lifetime measurements Journal of applied physiology (Bethesda, Md. 2004;97 (5):1962-1969 [PubMed]
  • Eerbeek Otto, Mik Egbert G., Zuurbier Coert J., van 't Loo Martijn, Donkersloot Cees, Ince Can Ratiometric intracellular calcium imaging in the isolated beating rat heart using indo-1 fluorescence Journal of applied physiology (Bethesda, Md. 2004;97 (6):2042-2050 [PubMed]
  • van Iterson M., Ince C. Resuscitation of the microcirculation with hemoglobin-based oxygen carriers following hemorrhagein: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2004. Berlin: Springer-Verlag; 2004. p. 762-779, ISBN 9783540207146
  • Ince C. The physiological genomics of the critically ill mouseBoston: Kluwer Academic Publishers; 2004. ISBN 9781402076411 (Basic Science for the Cardiologist)

2003

  • Ince C. A special section on mouse physiological genomics Clinical and experimental pharmacology & physiology 2003;30:867-909
  • Zuurbier Coert Jozef, Kruyver Bart, Eerbeek Otto, Mik Egbert Gezinus, Ince Can Commonly used numbers of microspheres affect cardiac vascular resistance Journal of cardiovascular pharmacology 2003;41 (2):223-232 [PubMed]
  • Dörffler-Melly Janine, de Kruif Martijn, Schwarte Lothar A., Franco Rendrik F., Florquin Sandrine, Spek C. Arnold, Ince Can, Reitsma Pieter H., ten Cate Hugo Functional thrombomodulin deficiency causes enhanced thrombus growth in a murine model of carotid artery thrombosis Basic research in cardiology 2003;98 (6):347-352 [PubMed]
  • van Iterson Mat, Siegemund Martin, Burhop Kenneth, Ince Can Hemoglobin-based oxygen carrier provides heterogeneous microvascular oxygenation in heart and gut after hemorrhage in pigs Journal of trauma 2003;55 (6):1111-1124 [PubMed]
  • Hardeman Max R., Besselink Geert A. J., Ebbing Iwan, de Korte Dirk, Ince Can, Verhoeven Arthur J. Laser-assisted optical rotational cell analyzer measurements reveal early changes in human RBC deformability induced by photodynamic treatment Transfusion 2003;43 (11):1533-1537 [PubMed]
  • Pittner Antje, Nalos Marek, Asfar Pierre, Yang Yan, Ince Can, Georgieff Michael, Brückner Uwe Bernd, Radermacher Peter, Fröba Gebhard Mechanisms of inducible nitric oxide synthase (iNOS) inhibition-related improvement of gut mucosal acidosis during hyperdynamic porcine endotoxemia Intensive care medicine 2003;29 (2):312-316 [PubMed]
  • Spronk P., Ince C., Gardien M., Mathura K., Zandstra D. Nitroglycerin for septic shock - Reply Lancet 2003;361 (9360):880
  • Buise M., van Bommel J., Ince C. Reflectance spectrophotometry and tissue oxygenation in experimental and clinical practicein: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2003. S.l.: s.n.; 2003. p. 221-231
  • Boerma E. C., Ince C. The microcirculation of the gut in sepsisin: A. Gullo, editors. Anesthesia, pain, intensive care and emergency medicine. S.l.: s.n.; 2003. p. 561-571, ISBN 9788848002356

2002

  • Asfar Pierre, Nalos Marek, Pittner Antje, Theisen Marc, Ichai Carole, Ploner Franz, Georgieff Michael, Ince Can, Brückner Uwe Bernd, Leverve Xavier Maurice, Radermacher Peter, Froeba Gebhard Adenosine triphosphate-magnesium dichloride during hyperdynamic porcine endotoxemia: Effects on hepatosplanchnic oxygen exchange and metabolism Critical care medicine 2002;30 (8):1826-1833 [PubMed]
  • Dobbe J. G. G., Hardeman M. R., Streekstra G. J., Strackee J., Ince C., Grimbergen C. A. Analyzing red blood cell-deformability distributions Blood cells, molecules & diseases 2002;28 (3):373-384 [PubMed]
  • Dobbe J. G. G. Engineering developments in hemorheology 2002. 133p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Grimbergen C. A., Ince C.; Co-supervisors: Hardeman M. R., Streekstra G. J.)
  • Mik Egbert G., Donkersloot Cornelis, Raat Nicolaas J. H., Ince Can Excitation pulse deconvolution in luminescence lifetime analysis for oxygen measurements in vivo Photochemistry and photobiology 2002;76 (1):12-21 [PubMed]
  • Jong Willeke M. C., Zuurbier Coert J., de Winter Robbert J., van den Heuvel Danyel A. F., Reitsma Pieter H., ten Cate Hugo, Ince Can Fentanyl-fluanisone-midazolam combination results in more stable hemodynamics than does urethane alpha-chloralose and 2,2,2-tribromoethanol in mice CONTEMPORARY TOPICS IN LABORATORY ANIMAL SCIENCE 2002;41 (3):28-32 [PubMed]
  • Zuurbier Coert J., Emons Vanessa M., Ince Can Hemodynamics of anesthetized ventilated mouse models: aspects of anesthetics, fluid support, and strain American journal of physiology. Heart and circulatory physiology 2002;282 (6):H2099-H2105 [PubMed]
  • van Bommel Jasper, Trouwborst Adrianus, Schwarte Lothar, Siegemund Martin, Ince Can, Henny Ch Pieter Intestinal and cerebral oxygenation during severe isovolemic hemodilution and subsequent hyperoxic ventilation in a pig model Anesthesiology 2002;97 (3):660-670 [PubMed]
  • Dobbe J. G. G., Streekstra G. J., Hardeman M. R., Ince C., Grimbergen C. A. Measurement of the distribution of red blood cell deformability using an automated rheoscope Cytometry 2002;50 (6):313-325 [PubMed]
  • Spronk Peter E., Ince Can, Gardien Martin J., Mathura Keshen R., Oudemans-van Straaten Heleen M., Zandstra Durk F. Nitroglycerin in septic shock after intravascular volume resuscitation Lancet 2002;360 (9343):1395-1396 [PubMed]
  • Buwalda Mattijn, Ince Can Opening the microcirculation: can vasodilators be useful in sepsis? Intensive care medicine 2002;28 (9):1208-1217 [PubMed]
  • Zuurbier C. J., Ince C. Post-ischaemic changes in the response time of oxygen consumption to demand in the isolated rat heart are mediated partly by calcium and glycolysis Pflugers Archiv 2002;443 (5-6):908-916 [PubMed]
  • van Bommel S. M., Racovitza I., Ince C. Sepsis, microcirculation and vasodilators Netherlands journal of critical care 2002;6:12-17
  • Ince C. The 3rd International Amsterdam Mouse Symposium - Introduction Clinical and experimental pharmacology & physiology 2002;29 (8):A69
  • Ince Can The microcirculation unveiled American journal of respiratory and critical care medicine 2002;166 (1):1-2 [PubMed]
  • Siegemund M., Racovitza I., Ince C. The rationale for vasodilator therapy in sepsisin: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2002. Berlin Heidelberg New York: Springer-Verlag; 2002. p. 221-232, ISBN 9783540431497

2001

  • Mathura K. R., Bouma G. J., Ince C. Abnormal microcirculation in brain tumours during surgery Lancet 2001;358 (9294):1698-1699 [PubMed]
  • Mathura K. R., Vollebregt K. C., Boer K., de Graaff J. C., Ubbink D. T., Ince C. Comparison of OPS imaging and conventional capillary microscopy to study the human microcirculation Journal of applied physiology (Bethesda, Md. 2001;91 (1):74-78 [PubMed]
  • Tepaske R., Velthuis H., Oudemans-van Straaten H. M., Heisterkamp S. H., van Deventer S. J., Ince C., Eÿsman L., Kesecioglu J. Effect of preoperative oral immune-enhancing nutritional supplement on patients at high risk of infection after cardiac surgery: a randomised placebo-controlled trial Lancet 2001;358 (9283):696-701 [PubMed]
  • Vollebregt K. C., Boer K., Mathura K. R., de Graaff J. C., Ubbink D. T., Ince C. Impaired vascular function in women with pre-eclampsia observed with orthogonal polarisation spectral imaging BJOG 2001;108 (11):1148-1153 [PubMed]
  • Tugtekin I. F., Radermacher P., Theisen M., Matejovic M., Stehr A., Ploner F., Matura K., Ince C., Georgieff M., Träger K. Increased ileal-mucosal-arterial PCO2 gap is associated with impaired villus microcirculation in endotoxic pigs Intensive care medicine 2001;27 (4):757-766 [PubMed]
  • van Bommel J., de Korte D., Lind A., Siegemund M., Trouwborst A., Verhoeven A. J., Ince C., Henny C. P. The effect of the transfusion of stored RBCs on intestinal microvascular oxygenation in the rat Transfusion 2001;41 (12):1515-1523 [PubMed]
  • Hardeman M. R., Dobbe J. G., Ince C. The Laser-assisted Optical Rotational Cell Analyzer (LORCA) as red blood cell aggregometer Clinical hemorheology and microcirculation 2001;25 (1):1-11 [PubMed]

2000

  • Mechanical ventilation of mice Basic research in cardiology 2000;95 (6):510-520 [PubMed]
  • Mouse models of focal arterial and venous thrombosis Basic research in cardiology 2000;95 (6):503-509 [PubMed]
  • Preservation of intestinal microvascular Po2 during normovolemic hemodilution in a rat model Journal of laboratory and clinical medicine 2000;135 (6):476-483 [PubMed]

1999

  • Assessment of regional tissue oxygenation Intensive care medicine 1999;25 (10):1044-1060 [PubMed]
  • Clinical potential of in vitro measured red cell deformability, a myth? Clinical hemorheology and microcirculation 1999;21 (3-4):277-284 [PubMed]
  • Functional heterogeneity of oxygen supply-consumption ratio in the heart Cardiovascular research 1999;44 (3):488-497 [PubMed]
  • Microcirculatory oxygenation and shunting in sepsis and shock Critical care medicine 1999;27 (7):1369-1377 [PubMed]
  • Microvascular oxygen pressure in the pig intestine during haemorrhagic shock and resuscitation Journal of physiology 1999;514 ( Pt 1):245-253 [PubMed]
  • Orthogonal polarization spectral imaging: a new method for study of the microcirculation Nature medicine 1999;5 (10):1209-1212 [PubMed]
  • PO2 measurements in the rat intestinal microcirculation American journal of physiology 1999;276 (6 Part 1):G1515-G1520 [PubMed]
  • Regional ischemia in hypertrophic Langendorff-perfused rat hearts American journal of physiology 1999;277 (4 Part 2):H1532-H1539 [PubMed]

1998

  • A novel method of evaluation of three heat-moisture exchangers in six different ventilator settings Intensive care medicine 1998;24 (2):138-146 [PubMed]
  • Intestinal microvascular pO2 measurement with Pd-porphyrin phosphorescence in the mechanically ventilated mouse Advances in experimental medicine and biology 1998;454:189-193 [PubMed]
  • Low-volume resuscitation with a hemoglobin-based oxygen carrier after hemorrhage improves gut microvascular oxygenation in swine Journal of laboratory and clinical medicine 1998;132 (5):421-431 [PubMed]
  • Monitoring normovolaemic haemodilution British journal of anaesthesia 1998;81 (Suppl. 1):73-78 [PubMed]
  • Red blood cell rigidification during cyclosporin therapy: a possible early warning signal for adverse reactions Scandinavian journal of clinical and laboratory investigation 1998;58 (8):617-623 [PubMed]

1997

  • Nitric oxide causes dysfunction of coronary autoregulation in endotoxemic rats Cardiovascular research 1997;35 (2):368-376 [PubMed]
  • Weak spots inside the myocardium of a Langendorff rat heart observed by NADH videofluorometry Advances in experimental medicine and biology 1997;411:347-351 [PubMed]

1996

  • Calibration of Pd-porphyrin phosphorescence for oxygen concentration measurements in vivo Journal of applied physiology (Bethesda, Md. 1996;81 (5):2297-2303 [PubMed]

1995

  • An experimental set-up to test heat-moisture exchangers Intensive care medicine 1995;21 (2):142-148 [PubMed]
  • Increase of cardiac work is associated with decrease of mitochondrial NADH American journal of physiology 1995;269 (3 Part 2):H856-H862 [PubMed]
  • Inhibition of nitric oxide synthesis causes myocardial ischemia in endotoxemic rats Circulation research 1995;76 (3):418-425 [PubMed]

1993

  • Heterogeneity of the hypoxic state in rat heart is determined at capillary level American journal of physiology 1993;264 (2 Part 2):H294-H301 [PubMed]

1990

  • Heterogeneous NADH fluorescence during post-anoxic reactive hyperemia in saline perfused rat heart Advances in experimental medicine and biology 1990;277:477-482 [PubMed]

1987

  • Ionic channels and membrane hyperpolarization in human macrophages Journal of membrane biology 1987;97 (3):251-258 [PubMed]

1986

  • Intracellular microelectrode measurements in small cells evaluated with the patch clamp technique Biophysical journal 1986;50 (6):1203-1209 [PubMed]

1984

  • Oscillatory hyperpolarizations and resting membrane potentials of mouse fibroblast and macrophage cell lines Journal of physiology 1984;352:625-635 [PubMed]