Prof. PhD S. Florquin publications

foto

Publications Prof. PhD S. Florquin

Position
Full Professor
Main activities
Patient care, Research
Specialisation
Pathologist
Focus of research

Immunopathology of renal transplantation.

The role of innate immunity in renal damage and repair. 

2020

  • de Boer Onno J., Krebbers Gabrielle, Mackaaij Claire, Florquin Sandrine, de Rie Menno A., van der Wal Allard C., Teunissen Marcel B. M. Comparison of Two Different Immunohistochemical Quadruple Staining Approaches to Identify Innate Lymphoid Cells in Formalin-fixed Paraffin-embedded Human Tissue journal of histochemistry and cytochemistry 2020;68 (2):127-138 [PubMed]
  • Kors L. NLRX1 and TFEB in metabolism and renal diseases 2020. 176p. ISBN 9789463756839. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisors: Leemans J. C., Tammaro A.)

2019

  • Bouatou Yassine, Nguyen Tri Q., Roelofs Joris J. T. H., Bemelman Frederike J., Michielsen Laura, Goldschmeding Roel, Kers Jesper, Florquin Sandrine A Multicenter Application of the 2018 Banff Classification for BK Polyomavirus-associated Nephropathy in Renal Transplantation Transplantation 2019;103 (12):2692-2700 [PubMed]
  • Uil Melissa, Scantlebery Angelique M. L., Butter Loes M., Larsen Per W. B., de Boer Onno J., Leemans Jaklien C., Florquin Sandrine, Roelofs Joris J. T. H. Author Correction: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain (Scientific Reports, (2018), 8, 1, (5542), 10.1038/s41598-018-23839-9) Scientific reports 2019;9 (1):3425 [PubMed]
  • de Porto Alexander P., Liu Zhe, de Beer Regina, Florquin Sandrine, de Boer Onno J., Hendriks Rudi W., van der Poll Tom, de Vos Alex F. Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia Molecular medicine (Cambridge, Mass.) 2019;25 (1):3 [PubMed]
  • Emal Diba, Rampanelli Elena, Claessen Nike, Bemelman Frederike J., Leemans Jaklien C., Florquin Sandrine, Dessing Mark C. Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection Scientific reports 2019;9 (1) [PubMed]
  • Rondeau Eric, Luyckx Valerie A., Anders Hans-Joachim, Eckardt Kai-Uwe, Florquin Sandrine, Marti Hans-Peter, Ølgaard Klaus, Harden Paul Challenges and opportunities for nephrology in Western Europe Kidney international 2019;95 (5):1037-1040 [PubMed]
  • Emal Diba Damage-associated molecular patterns, commensals and pathogens in renal pathology 2019. 159p. ISBN 9789463754439. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisors: Dessing M. C. , Leemans J. C.)
  • Hermsen Meyke, de Bel Thomas, den Boer Marjolijn, Steenbergen Eric J., Kers Jesper, Florquin Sandrine, Roelofs Joris J. T. H., Stegall Mark D., Alexander Mariam P., Smith Byron H., Smeets Bart, Hilbrands Luuk B., van der Laak Jeroen A. W. M. Deep Learning-Based Histopathologic Assessment of Kidney Tissue Clinical journal of the American Society of Nephrology 2019;30 (10):1968-1979 [PubMed]
  • Demirok Aysenur, Ranzijn Claudia, Lardy Junior, Florquin Sandrine, Bouts Antonia Evaluation of the current post-transplantation Human Leukocyte Antigen antibody screening in pediatric renal transplant recipients Pediatric transplantation 2019;23 (2):e13338 [PubMed]
  • Jansen Marcel. P. B., Huisman Andras, Claessen Nike, Florquin Sandrine, Roelofs Joris J. T. H. Experimental thrombocytopenia does not affect acute kidney injury 24 hours after renal ischemia reperfusion in mice Platelets 2019 [PubMed]
  • Pieters Tobias T., Falke Lucas L., Nguyen Tri Q., Verhaar Marianne C., Florquin Sandrine, Bemelman Frederike J., Kers Jesper, Vanhove Thomas, Kuypers Dirk, Goldschmeding Roel, Rookmaaker Maarten B. Histological characteristics of Acute Tubular Injury during Delayed Graft Function predict renal function after renal transplantation Physiological reports 2019;7 (5) [PubMed]
  • Bouatou Yassine R. Improving the contribution of histopathology in kidney diseases: From diagnosis to prognosis 2019. 169p. ISBN 9789463753562. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisors: Roelofs J. J. T. H. , Kers J.)
  • Scantlebery Angelique M. L., Uil Melissa, Butter Loes M., Poelman Renée, Claessen Nike, Girardin Stephen E., Florquin Sandrine, Roelofs Joris J. T. H., Leemans Jaklien C. NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin PLoS ONE 2019;14 (3) [PubMed]
  • Waasdorp Maaike, Florquin Sandrine, Duitman JanWillem, Spek C. Arnold Pharmacological PAR-1 inhibition reduces blood glucose levels but does not improve kidney function in experimental type 2 diabetic nephropathy FASEB journal 2019;33 (10):10966-10972 [PubMed]
  • de Porto Alexander P. N. A., Claushuis Theodora A. M., van der Donk Lieve E. H., de Beer Regina, de Boer Onno J., Florquin Sandrine, Roelofs Joris J. T. H., Hendriks Rudi W., van der Poll Tom, van't Veer Cornelis, de Vos Alex F. Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis Thrombosis and haemostasis 2019;119 (6):930-940 [PubMed]
  • Veltkamp Floor, Khan Djera H., Reefman Christa, Veissi Susan, van Oers Hedy A., Levtchenko Elena, Mathôt Ron A. A., Florquin Sandrine, van Wijk Joanna A. E., Schreuder Michiel F., Haverman Lotte, Bouts Antonia H. M. Prevention of relapses with levamisole as adjuvant therapy in children with a first episode of idiopathic nephrotic syndrome: Study protocol for a double blind, randomised placebo-controlled trial (the LEARNS study) BMJ open 2019;9 (8):e027011 [PubMed]
  • Waasdorp Maaike, de Rooij Dennis M., Florquin Sandrine, Duitman JanWillem, Spek C. Arnold Protease-activated receptor-1 contributes to renal injury and interstitial fibrosis during chronic obstructive nephropathy Journal of cellular and molecular medicine 2019;23 (2):1268-1279 [PubMed]
  • Perlee Desirée, de Vos Alex F., Scicluna Brendon P., Maag Anja, Mancheño Pablo, de la Rosa Olga, Dalemans Wilfried, Florquin Sandrine, van't Veer Cornelis, Lombardo Eleuterio, van der Poll Tom Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice STEM CELL RESEARCH & THERAPY 2019;10 (1) [PubMed]
  • Tammaro Alessandra, Scantlebery Angelique M. L., Rampanelli Elena, Borrelli Cristiana, Claessen Nike, Butter Loes M., Soriani Alessandra, Colonna Marco, Leemans Jaklien C., Dessing Mark C., Florquin Sandrine TREM1/3 deficiency impairs tissue repair after acute kidney injury and mitochondrial metabolic flexibility in tubular epithelial cells Frontiers in immunology 2019;10 (JULY) [PubMed]
  • Scantlebery Angelique M. L., Ochodnicky Peter, Kors Lotte, Rampanelli Elena, Butter Loes M., el Boumashouli Chaima, Claessen Nike, Teske Gwen J., van den Bergh Weerman Marius A., Leemans Jaklien C., Roelofs Joris J. T. H., Florquin Sandrine β-Cyclodextrin counteracts obesity in Western diet-fed mice but elicits a nephrotoxic effect Scientific reports 2019;9 (1) [PubMed]

2018

  • Bouatou Yassine, Stokman Geurt, Claessen Nike, Roelofs Joris J. T. H., Bemelman Frédérike, Kers Jesper, Florquin Sandrine Aryl hydrocarbon receptor expression by macrophages and lymphocytes within infiltrates in BK polyomavirus associated nephropathy Transplant immunology 2018;47:18-21 [PubMed]
  • van Lieshout Miriam H. P., de Vos Alex F., Dessing Mark C., de Porto Alexander P. N. A., de Boer Onno J., de Beer Regina, Terpstra Sanne, Florquin Sandrine, van't Veer Cornelis, van der Poll Tom ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice European journal of immunology 2018;48 (1):66-79 [PubMed]
  • Eymael Jennifer, Sharma Shagun, Loeven Markus A., Wetzels Jack F., Mooren Fieke, Florquin Sandrine, Deegens Jeroen K., Willemsen Brigith K., Sharma Vikram, van Kuppevelt Toin H., Bakker Marinka A., Ostendorf Tammo, Moeller Marcus J., Dijkman Henry B., Smeets Bart, van der Vlag Johan CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis Kidney international 2018;93 (3):626-642 [PubMed]
  • Uil Melissa, Scantlebery Angelique M. L., Butter Loes M., Larsen Per W. B., de Boer Onno J., Leemans Jaklien C., Florquin Sandrine, Roelofs Joris J. T. H. Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the 'resistant' C57Bl/6J mouse strain Scientific reports 2018;8 (1) [PubMed]
  • Kors Lotte, Rampanelli Elena, Stokman Geurt, Butter Loes M., Held Ntsiki M., Claessen Nike, Larsen Per W. B., Verheij Joanne, Zuurbier Coert J., Liebisch Gerhard, Schmitz Gerd, Girardin Stephen E., Florquin Sandrine, Houtkooper Riekelt H., Leemans Jaklien C. Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2018;1864 (5):1883-1895 [PubMed]
  • Bouatou Yassine, Kers Jesper, Chevalier-Florquin Marie S. N., Claessen Nike, Nguyen Tri Q., Damman Jeffrey, Proenca Henrique, Roelofs Joris J. T. H., Florquin Sandrine Diagnostic accuracy of immunofluorescence versus immunoperoxidase staining to distinguish immune complex-mediated glomerulonephritis and C3 dominant glomerulopathy Histopathology 2018;72 (4):601-608 [PubMed]
  • Falix Farah A., Oosterveld Michiel J. S., Florquin Sandrine, Groothoff Jaap W., Bouts Antonia H. M. Diagnostic dilemmas in a girl with acute glomerulonephritis: Answers Pediatric nephrology (Berlin, Germany) 2018;33 (1):65-69 [PubMed]
  • Falix Farah A., Oosterveld Michiel J. S., Florquin Sandrine, Groothoff Jaap W., Bouts Antonia H. M. Diagnostic dilemmas in a girl with acute glomerulonephritis: Questions Pediatric nephrology (Berlin, Germany) 2018;33 (1):63-64 [PubMed]
  • van Sandwijk Marit S., de Vries Aiko P. J., Bakker Stephan J. L., ten Berge Ineke J. M., Berger Stefan P., Bouatou Yassine R., de Fijter Johan W., Florquin Sandrine, Homan van der Heide Jaap J., Idu Mirza M., Krikke Christina, van der Pant Karlijn A. M. I., Reinders Marlies E., Ringers Jan, van der Weerd Neelke C., Bemelman Frederike J., Sanders Jan-Stephan S. Early steroid withdrawal compared with standard immunosuppression in kidney transplantation - Interim analysis of the Amsterdam-Leiden-Groningen randomized controlled trial Transplantation direct 2018;4 (6):e354 [PubMed]
  • Waasdorp Maaike, Duitman Jan-Willem, Florquin Sandrine, Spek C Arnold Erratum: Protease activated receptor 2 in diabetic nephropathy: a double edged sword American journal of translational research 2018;10 (7):2220 [PubMed]
  • Rampanelli Elena, Ochodnicky Peter, Vissers Johannes P. C., Butter Loes M., Claessen Nike, Calcagni Alessia, Kors Lotte, Gethings Lee A., Bakker Stephan J. L., de Borst Martin H., Navis Gerjan J., Liebisch Gerhard, Speijer Dave, van den Bergh Weerman Marius A., Jung Bettina, Aten Jan, Steenbergen Eric, Schmitz Gerd, Ballabio Andrea, Florquin Sandrine, Aerts Johannes M. FG, Leemans Jaklien C. Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney Journal of pathology 2018;246 (4):470-484 [PubMed]
  • Tammaro Alessandra Immune-mediated mechanisms of (mal)adaptive renal tissue repair 2018. ISBN 9789463750622. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisors: Dessing M. C., Leemans J. C.)
  • Jansen Marcel P. B., Pulskens Wilco P., Butter Loes M., Florquin Sandrine, Juffermans Nicole P., Roelofs Joris J. T. H., Leemans Jaklien C. Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction Shock (Augusta, Ga.) 2018;49 (3):301-310 [PubMed]
  • Kors Lotte, Butter Loes M., Claessen Nike, Teske Gwendoline J. D., Girardin Stephen E., Florquin Sandrine, Leemans Jaklien C. Nlrx1 is not involved in the host defense against escherichia coli induced pyelonephritis [version 3; peer review: 1 approved, 1 not approved] F1000Research 2018;7
  • Stroo Ingrid, Emal Diba, Butter Loes M., Teske Gwen J., Claessen Nike, Dessing Mark C., Girardin Stephen E., Florquin Sandrine, Leemans Jaklien C. No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction BMC nephrology 2018;19 (1) [PubMed]
  • Waasdorp Maaike Protease-activated receptors in diabetic nephropathy and renal fibrosis 2018. ISBN 9789463800709. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Florquin S.; Co-supervisors: Spek C. A., Duitman J. W.)
  • Jansen Marcel P. B., Florquin Sandrine, Roelofs Joris J. T. H. The role of platelets in acute kidney injury Nature reviews. Nephrology 2018;14 (7):457-471 [PubMed]
  • Jansen Marcel P. B. The role of platelets in acute kidney injury 2018. 203p. ISBN 9789463801454. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Roelofs J. J. T. H.)
  • Waasdorp Maaike, Duitman JanWillem, Florquin Sandrine, Spek C. Arnold Vorapaxar treatment reduces mesangial expansion in streptozotocin-induced diabetic nephropathy in mice Oncotarget 2018;9 (31):21655-21662 [PubMed]

2017

  • van den Hoogen Martijn W. F., Steenbergen Eric J., Baas Marije C., Florquin Sandrine, Hilbrands Luuk B. Absence of Intragraft B Cells in Rejection Biopsies After Rituximab Induction Therapy: Consequences for Clinical Outcome Transplantation direct 2017;3 (4):e143 [PubMed]
  • Riool M., Dirks A. J., Jaspers V., de Boer L., Loontjens T. J., van der Loos C. M., Florquin S., Apachitei I., Rijk L. N., Keul H. A., Zaat S. A. A chlorhexidine-releasing epoxy-based coating on titanium implants prevents Staphylococcus aureus experimental biomaterial-associated infection European cells & materials 2017;33:143-157 [PubMed]
  • Falix Farah A., Bennebroek Carlien A. M., van der Zwaag Bert, Lapid-Gortzak Ruth, Florquin Sandrine, Oosterveld Michiel J. S. A novel mutation of laminin beta 2 (LAMB2) in two siblings with renal failure European journal of pediatrics 2017;176 (4):515-519 [PubMed]
  • Tammaro Alessandra, Kers Jesper, Emal Diba, Stroo Ingrid, Teske Gwendoline J. D., Butter Loes M., Claessen Nike, Damman Jeffrey, Derive Marc, Navis Gerjan J., Florquin Sandrine, Leemans Jaklien C., Dessing Mark C. Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation Scientific reports 2017;7:44163 [PubMed]
  • Emal Diba, Rampanelli Elena, Stroo Ingrid, Butter Loes M., Teske Gwendoline J., Claessen Nike, Stokman Geurt, Florquin Sandrine, Leemans Jaklien C., Dessing Mark C. Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury Journal of the American Society of Nephrology 2017;28 (5):1450-1461 [PubMed]
  • Bemelman F. J., de Fijter J. W., Kers J., Meyer C., Peters-Sengers H., de Maar E. F., van der Pant K. A. M. I., de Vries A. P. J., Sanders J.-S., Zwinderman A., Idu M. M., Berger S., Reinders M. E. J., Krikke C., Bajema I. M., van Dijk M. C., ten Berge I. J. M., Ringers J., Lardy J., Roelen D., Moes D.-J., Florquin S., Homan van der Heide J. J. Early Conversion to Prednisolone/Everolimus as an Alternative Weaning Regimen Associates With Beneficial Renal Transplant Histology and Function: The Randomized-Controlled MECANO Trial American journal of transplantation 2017;17 (4):1020-1030 [PubMed]
  • Anas Adam A., Claushuis Theodora A. M., Mohan Rajiv A., Christoffels Vincent M., Aidinis Vassilis, Florquin Sandrine, van't Veer Cornelis, Hou Baidong, de Vos Alex F., van der Poll Tom Epithelial Myeloid-Differentiation Factor 88 Is Dispensable during Klebsiella Pneumonia American journal of respiratory cell and molecular biology 2017;56 (5):648-656 [PubMed]
  • Bellur Shubha S., Lepeytre Fanny, Vorobyeva Olga, Troyanov Stéphan, Cook H. Terence, Roberts Ian S. D., Alpers Charles E., Amore Alessandro, Barratt Jonathan, Berthoux Francois, Bonsib Stephen, Bruijn Jan A., Cattran Daniel C., Coppo Rosanna, D'Agati Vivette, D'Amico Giuseppe, Emancipator Steven, Emma Francesco, Feehally John, Ferrario Franco, Fervenza Fernando C., Florquin Sandrine, Fogo Agnes, Geddes Colin C., Groene Hermann-Josef, Haas Mark, Herzenberg Andrew M., Hill Prue A., Hogg Ronald J., Hsu Stephen I., Jennette J. Charles, Joh Kensuke, Julian Bruce A., Kawamura Tetsuya, Lai Fernand M., Li Lei-Shi, Li Philip K. T., Liu Zhi-Hong, Mackinnon Bruce, Mezzano Sergio, Schena F. Paolo, Tomino Yasuhiko, Walker Patrick D., Wang Haiyan, Weening Jan J., Yoshikawa Nori, Zhang Hong Evidence from the Oxford Classification cohort supports the clinical value of subclassification of focal segmental glomerulosclerosis in IgA nephropathy Kidney international 2017;91 (1):235-243 [PubMed]
  • García-Laorden M. Isabel, Stroo Ingrid, Terpstra Sanne, Florquin Sandrine, Medema Jan Paul, van T Veer Cornelis, de Vos Alex F., van der Poll Tom Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis Mediators of inflammation 2017;2017:4137563 [PubMed]
  • Mesarosova Lucia, Ochodnicky Peter, Leemans Jaklien C., Florquin Sandrine, Krenek Peter, Klimas Jan High glucose induces HGF-independent activation of Met receptor in human renal tubular epithelium Journal of receptor and signal transduction research 2017;37 (6):535-542 [PubMed]
  • Maicas Nuria, van der Vlag Johan, Bublitz Janin, Florquin Sandrine, Bakker-van Bebber Marinka, Dinarello Charles A., Verweij Vivienne, Masereeuw Roos, Joosten Leo A., Hilbrands Luuk B. Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury PLoS ONE 2017;12 (2):e0168981 [PubMed]
  • Ochodnicky Peter, Lattenist Lionel, Ahdi Mohamed, Kers Jesper, Uil Melissa, Claessen Nike, Leemans Jaklien C., Florquin Sandrine, Meijers Joost C. M., Gerdes Victor E. A., Roelofs Joris J. T. H. Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy American journal of pathology 2017;187 (9):1971-1983 [PubMed]
  • Rampanelli Elena, Orsó Evelyn, Ochodnicky Peter, Liebisch Gerhard, Bakker Pieter J., Claessen Nike, Butter Loes M., van den Bergh Weerman Marius A., Florquin Sandrine, Schmitz Gerd, Leemans Jaklien C. Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation Scientific reports 2017;7 (1):2861 [PubMed]
  • Stokman Geurt, Kors Lotte, Bakker Pieter J., Rampanelli Elena, Claessen Nike, Teske Gwendoline J. D., Butter Loes, van Andel Harmen, van den Bergh Weerman Marius A., Larsen Per W. B., Dessing Mark C., Zuurbier Coert J., Girardin Stephen E., Florquin Sandrine, Leemans Jaklien C. NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity Journal of experimental medicine 2017;214 (8):2405-2420 [PubMed]
  • Waasdorp Maaike, Duitman Janwillem, Florquin Sandrine, Spek Arnold C. Protease activated receptor 2 in diabetic nephropathy: a double edged sword American journal of translational research 2017;9 (10):4512-4520 [PubMed]
  • Jansen Marcel P. B., Emal Diba, Teske Gwendoline J. D., Dessing Mark C., Florquin Sandrine, Roelofs Joris J. T. H. Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps Kidney international 2017;91 (2):352-364 [PubMed]
  • Tammaro Alessandra, Derive Marc, Gibot Sebastien, Leemans Jaklien C., Florquin Sandrine, Dessing Mark C. TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives Pharmacology & therapeutics 2017;177:81-95 [PubMed]

2016

  • Sonneveld Ramon, Hoenderop Joost G. J., Stavenuiter Andrea W. D., Ferrantelli Evelina, Baltissen Marijke P. A., Dijkman Henry B., Florquin Sandrine, Rops Angelique L., Wetzels Jack F. M., Berden Jo H. M., van der Vlag Johan, Nijenhuis Tom 1,25-Vitamin D3 Deficiency Induces Albuminuria American journal of pathology 2016;186 (4):794-804 [PubMed]
  • Lattenist Lionel, Jansen Marcel P. B., Teske Gwendoline, Claessen Nike, Meijers Joost C. M., Rezaie Alireza R., Esmon Charles T., Florquin Sandrine, Roelofs Joris J. T. H. Activated protein C protects against renal ischaemia/reperfusion injury, independent of its anticoagulant properties Thrombosis and haemostasis 2016;116 (1):124-133 [PubMed]
  • Kers Jesper Determinants of acute and chronic renal allograft injury 2016. 383p. ISBN 9789462993518. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin S., ten Berge R. J. M.; Co-supervisors: Bemelman F. J., Dessing M. C.)
  • Dessing Mark C., Kers Jesper, Damman Jeffrey, Navis Gerjan J., Florquin Sandrine, Leemans Jaklien C. Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation Scientific reports 2016;6:36315 [PubMed]
  • Tammaro A., Kers J., Emal D., Stroo I., Teske G. J. D., Butter L. M., Claessen N., Damman J., Derive M., Navis G., Florquin S., Leemans J. C., Dessing M. C. Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation Scientific reports 2016;6:38275 [PubMed]
  • Anas Adam A., de Vos Alex F., Hoogendijk Arie J., van Lieshout Miriam H. P., van Heijst Jeroen W. J., Florquin Sandrine, Li Zihai, van 't Veer Cornelis, van der Poll Tom Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia Journal of pathology 2016;238 (1):74-84 [PubMed]
  • García-Laorden M. Isabel, Stroo Ingrid, Blok Dana C., Florquin Sandrine, Medema Jan Paul, de Vos Alex F., van der Poll Tom Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia Journal of innate immunity 2016;8 (3):258-268 [PubMed]
  • Yapici Ünsal, Kers Jesper, Slavujevic-Letic Ivana, Stokman Geurt, Roelofs Joris J. T. H., van Aalderen Michiel C., Groothoff Jaap W., de Boer Onno J., van der Pant Karlijn A. M. I., Claessen Nike, Hilbrands Luuk B., Bemelman Frederike J., ten Berge Ineke J. M., Florquin Sandrine Intragraft Blood Dendritic Cell Antigen-1-Positive Myeloid Dendritic Cells Increase during BK Polyomavirus-Associated Nephropathy Journal of the American Society of Nephrology 2016;27 (8):2502-2510 [PubMed]
  • Anas Adam A., van Lieshout Miriam H. P., Claushuis Theodora A. M., de Vos Alex F., Florquin Sandrine, de Boer Onno J., Hou Baidong, van't Veer Cornelis, van der Poll Tom Lung epithelial MyD88 drives early pulmonary clearance of Pseudomonas aeruginosa by a flagellin dependent mechanism American journal of physiology. Lung cellular and molecular physiology 2016;311 (2):L219-L228 [PubMed]
  • Stokman Geurt, Kers Jesper, Yapici Ünsal, Hoelbeek Joris J., Claessen Nike, de Boer Onno J., Netea Mihai G., Hilbrands Luuk, Bemelman Fréderike J., ten Berge Ineke J. M., Florquin Sandrine Predominant Tubular Interleukin-18 Expression in Polyomavirus-Associated Nephropathy Transplantation 2016;100 (10):e88-e95 [PubMed]
  • Waasdorp Maaike, Duitman Janwillem, Florquin Sandrine, Spek C. Arnold Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice Scientific reports 2016;6:33030 [PubMed]
  • Achouiti Ahmed, de Vos Alex F., van 't Veer Cornelis, Florquin Sandrine, Tanck Michael W., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom, van Zoelen Marieke A. D. Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia PLoS ONE 2016;11 (1):e0141000 [PubMed]
  • Lattenist L., Ochodnický P., Ahdi M., Claessen N., Leemans J. C., Satchell S. C., Florquin S., Gerdes V. E., Roelofs J. J. T. H. Renal endothelial protein C receptor expression and shedding during diabetic nephropathy Journal of thrombosis and haemostasis 2016;14 (6):1171-1182 [PubMed]
  • Bueters Ruud R. G., Jeronimus-Klaasen Annelies, Maicas Nuria, Florquin Sandrine, van den Heuvel Lambertus P., Schreuder Michiel F. The Effects of Early Postnatal Diuretics Treatment on Kidney Development and Long-Term Kidney Function in Wistar Rats Nephron 2016;132 (2):110-118 [PubMed]
  • Barbour Sean J., Espino-Hernandez Gabriela, Reich Heather N., Coppo Rosanna, Roberts Ian S. D., Feehally John, Herzenberg Andrew M., Cattran Daniel C., Bavbek N., Cook T., Troyanov S., Alpers C., Amore A., Barratt J., Berthoux F., Bonsib S., Bruijn J., D'Agati V., D'Amico G., Emancipator S., Emmal F., Ferrario F., Fervenza F., Florquin S., Fogo A., Geddes C., Groene H., Haas M., Hill P., Hogg R., Hsu S., Hunley T., Hladunewich M., Jennette C., Joh K., Julian B., Kawamura T., Lai F., Leung C., Li L., Li P., Liu Z., Massat A., MacKinnon B., Mezzano S., Schena F., Tomino Y., Walker P., Wang H., Weening J. The MEST score provides earlier risk prediction in lgA nephropathy Kidney international 2016;89 (1):167-175 [PubMed]
  • Lattenist Lionel The Protein C system in renal disease 2016. 213p. ISBN 9789491602627. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Roelofs J. J. T. H.)
  • van der Meer Anne Jan, Achouiti Achmed, van der Ende Arie, Soussan Aicha A., Florquin Sandrine, de Vos Alex, Zeerleder Sacha S., van der Poll Tom Toll-like receptor 9 enhances bacterial clearance and limits lung consolidation in murine pneumonia caused by methicillin resistant Staphylococcus aureus Molecular medicine (Cambridge, Mass.) 2016;22:292-299 [PubMed]
  • Hoelbeek Joris, Duivenvoorden Raphaël, de Boer Onno J., Claessen Nike, van den Bergh Weerman Marius A., Roelofs Joris J. T. H., Kers Jesper, ten Berge Ineke J. M., Florquin Sandrine Unique Renal Manifestation of Type I Cryoglobulinemia, With Massive Crystalloid Deposits in Glomerular Histiocytes, Podocytes, and Endothelial Cells American journal of clinical pathology 2016;145 (2):282-285 [PubMed]

2015

  • van der Tol Linda, Svarstad Einar, Ortiz Alberto, Tøndel Camilla, Oliveira João Paulo, Vogt Liffert, Waldek Stephen, Hughes Derralynn A., Lachmann Robin H., Terryn Wim, Hollak Carla E., Florquin Sandrine, van den Bergh Weerman Marius A., Wanner Christoph, West Michael L., Biegstraaten Marieke, Linthorst Gabor E. Chronic kidney disease and an uncertain diagnosis of Fabry disease: Approach to a correct diagnosis Molecular genetics and metabolism 2015;114 (2):242-247 [PubMed]
  • Stroo Ingrid, Claessen Nike, Teske Gwendoline J. D., Butter Loes M., Florquin Sandrine, Leemans Jaklien C. Deficiency for the chemokine monocyte chemoattractant protein-1 aggravates tubular damage after renal ischemia/reperfusion injury PLoS ONE 2015;10 (4):e0123203 [PubMed]
  • Smid B. E., Hollak C. E. M., Poorthuis B. J. H. M., van den Bergh Weerman M. A., Florquin S., Kok W. E. M., Lekanne Deprez R. H., Timmermans J., Linthorst G. E. Diagnostic dilemmas in Fabry disease: a case series study on GLA mutations of unknown clinical significance Clinical genetics 2015;88 (2):161-166 [PubMed]
  • Oosterveld Michiel J. S., Garrelfs Mark R., Hoppe Bernd, Florquin Sandrine, Roelofs Joris J. T. H., van den Heuvel L. P., Amann Kerstin, Davin Jean-Claude, Bouts Antonia H. M., Schriemer Pietrik J., Groothoff Jaap W. Eculizumab in Pediatric Dense Deposit Disease Clinical journal of the American Society of Nephrology 2015;10 (10):1773-1782 [PubMed]
  • Kers Jesper, Florquin Sandrine Generation of Alloreactive-Anergized Tr1 Cells From Patients on Dialysis for the Induction of Renal Transplant Tolerance: Are We There Yet? Transplantation 2015;99 (8):1551-1552 [PubMed]
  • Bueters Ruud R. G., Klaasen Annelies, Maicas Nuria, Florquin Sandrine, van den Heuvel Lambertus P., Schreuder Michiel F. Impact of Early Postnatal NSAID Treatment on Nephrogenesis in Wistar Rats Birth defects research. Part B, Developmental and reproductive toxicology 2015;104 (5):218-226 [PubMed]
  • Scicluna Brendon P., van Lieshout Miriam H., Blok Dana C., Florquin Sandrine, van der Poll Tom Modular Transcriptional Networks of the Host Pulmonary Response during Early and Late Pneumococcal Pneumonia Molecular medicine (Cambridge, Mass.) 2015;21 (1):430-441 [PubMed]
  • Achouiti Ahmed, Vogl Thomas, van der Meer Anne J., Stroo Ingrid, Florquin Sandrine, de Boer Onno J., Roth Johannes, Zeerleder Sacha, van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia European respiratory journal 2015;46 (2):464-473 [PubMed]
  • van den Hoogen M. W. F., Kamburova E. G., Baas M. C., Steenbergen E. J., Florquin S., M Koenen H. J. P., Joosten I., Hilbrands L. B. Rituximab as Induction Therapy After Renal Transplantation: A Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety American journal of transplantation 2015;15 (2):407-416 [PubMed]
  • Hommes Tijmen J., van Lieshout Miriam H., van 't Veer Cornelis, Florquin Sandrine, Bootsma Hester J., Hermans Peter W., de Vos Alex F., van der Poll Tom Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia PLoS ONE 2015;10 (12):e0145138 [PubMed]
  • Hommes Tijmen J., Dessing Mark C., Veer Cornelis van 't, Florquin Sandrine, Colonna Marco, de Vos Alex F., van der Poll Tom Role of Triggering Receptor Expressed on Myeloid Cells-1/3 in Klebsiella-Derived Pneumosepsis American journal of respiratory cell and molecular biology 2015;53 (5):647-655 [PubMed]
  • Dessing Mark C., Tammaro Alessandra, Pulskens Wilco P., Teske Gwendoline J., Butter Loes M., Claessen Nike, van Eijk Marco, van der Poll Tom, Vogl Thomas, Roth Johannes, Florquin Sandrine, Leemans Jaklien C. The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion Kidney international 2015;87 (1):85-94 [PubMed]
  • Lattenist Lionel, Teske Gwendoline, Claessen Nike, Florquin Sandrine, Conway Edward M., Roelofs Joris J. T. H. The lectin like domain of thrombomodulin is involved in the defence against pyelonephritis Thrombosis research 2015;136 (6):1325-1331 [PubMed]
  • de Vos Alex F., Dessing Mark C., Lammers Adriana J. J., de Porto Alexander P. N. A., Florquin Sandrine, de Boer Onno J., de Beer Regina, Terpstra Sanne, Bootsma Hester J., Hermans Peter W., van 't Veer Cornelis, van der Poll Tom The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice PLoS ONE 2015;10 (2):e0118181 [PubMed]
  • Sentís Alexis, Kers Jesper, Yapici Unsal, Claessen Nike, Roelofs Joris J. T. H., Bemelman Frederike J., ten Berge Ineke J. M., Florquin Sandrine The prognostic significance of glomerular infiltrating leukocytes during acute renal allograft rejection Transplant immunology 2015;33 (3):168-175 [PubMed]
  • van Lieshout Miriam H. P., Florquin Sandrine, Vanʼt Veer Cornelis, de Vos Alex F., van der Poll Tom TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Mediates Antibacterial Defense during Gram-Negative Pneumonia by Inducing Interferon-x03B3 Journal of innate immunity 2015;7 (6):637-646 [PubMed]
  • Bakker Pieter Jeroen Tissue-specific roles of the pattern recognition receptors NLRP3, NLRX1 and TLR9 in sterile inflammatory kidney disease 2015. 160p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Leemans J. C.)
  • Bakker Pieter J., Scantlebery Angelique M., Butter Loes M., Claessen Nike, Teske Gwendoline J. D., van der Poll Tom, Florquin Sandrine, Leemans Jaklien C. TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion PLoS ONE 2015;10 (9):e0137511 [PubMed]
  • Dessing Mark C., Kers Jesper, Damman Jeffrey, Leuvenink Henri G. D., van Goor Harry, Hillebrands Jan-Luuk, Hepkema Bouke G., Snieder Harold, van den Born Jacob, de Borst Martin H., Bakker Stephan J. L., Navis Gerjan J., Ploeg Rutger J., Florquin Sandrine, Seelen Marc, Leemans Jaklien C. Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation PLoS ONE 2015;10 (10):e0139769 [PubMed]

2014

  • Bakker Pieter J., Butter Loes M., Claessen Nike, Teske Gwendoline J. D., Sutterwala Fayyaz S., Florquin Sandrine, Leemans Jaklien C. A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion American journal of pathology 2014;184 (7):2013-2022 [PubMed]
  • Duitman Janwillem, Borensztajn Keren S., Pulskens Willem P. C., Leemans Jaklien C., Florquin Sandrine, Spek C. Arnold CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy Laboratory investigation; a journal of technical methods and pathology 2014;94 (1):89-97 [PubMed]
  • Rampanelli Elena CD44, TLR4, TREM-1/DAP12 in renal injury, inflammation and fibrosis 2014. 191p. ISBN 9789461824349. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Leemans J. C.)
  • Hommes Tijmen J., Hoogendijk Arie J., Dessing Mark C., van't Veer Cornelis, Florquin Sandrine, de Vos Alex F., van der Poll Tom DNAX-Activating Protein of 12 kDa Impairs Host Defense in Pneumococcal Pneumonia Critical care medicine 2014;42 (12):E783-E790 [PubMed]
  • Stokman Geurt, Qin Yu, Booij Tijmen H., Ramaiahgari Sreenivasa, Lacombe Marie, Dolman M. Emmy M., van Dorenmalen Kim M. A., Teske Gwendoline J. D., Florquin Sandrine, Schwede Frank, van de Water Bob, Kok Robbert J., Price Leo S. Epac-Rap signaling reduces oxidative stress in the tubular epithelium Journal of the American Society of Nephrology 2014;25 (7):1474-1485 [PubMed]
  • van Lieshout Miriam H. P., Anas Adam A., Florquin Sandrine, Hou Baidong, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis PLoS pathogens 2014;10 (9):e1004368 [PubMed]
  • Duitman Jan Willem Infectious diseases and fibrotic disorders: potential novel targets 2014. 194p. ISBN 9789088918636. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin Sandrine, van der Poll Tom; Co-supervisors: Spek Arnold, Peppelenbosch M. P.)
  • Achouiti Ahmed, Vogl Thomas, Endeman Henrik, Mortensen Brittany L., Laterre Pierre-Francois, Wittebole Xavier, van Zoelen Marieke A. D., Zhang Yaofang, Hoogerwerf Jacobien J., Florquin Sandrine, Schultz Marcus J., Grutters Jan C., Biesma Douwe H., Roth Johannes, Skaar Eric P., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia Thorax 2014;69 (11):1034-1042 [PubMed]
  • van Lieshout Miriam H., Scicluna Brendon P., Florquin Sandrine, van der Poll Tom NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumonia American journal of respiratory cell and molecular biology 2014;50 (4):699-712 [PubMed]
  • Bakker Pieter J., Butter Loes M., Kors Lotte, Teske Gwendoline J. D., Aten Jan, Sutterwala Fayyaz S., Florquin Sandrine, Leemans Jaklien C. Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation Kidney international 2014;85 (5):1112-1122 [PubMed]
  • Pulskens Wilco P., Butter Loes M., Teske Gwendoline J., Claessen Nike, Dessing Mark C., Flavell Richard A., Sutterwala Fayyaz S., Florquin Sandrine, Leemans Jaklien C. Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction PLoS ONE 2014;9 (1):e85775 [PubMed]
  • Rampanelli Elena, Rouschop Kasper M. A., Claessen Nike, Teske Gwendoline J. D., Pals Steven T., Leemans Jaklien C., Florquin Sandrine Opposite role of CD44-standard and CD44-variant-3 in tubular injury and development of renal fibrosis during chronic obstructive nephropathy Kidney international 2014;86 (3):558-569 [PubMed]
  • Leemans Jaklien C., Kors Lotte, Anders Hans-Joachim, Florquin Sandrine Pattern recognition receptors and the inflammasome in kidney disease Nature reviews. Nephrology 2014;10 (7):398-414 [PubMed]
  • Duitman Janwillem, Ruela-de-Sousa Roberta R., Shi Kun, de Boer Onno J., Borensztajn Keren S., Florquin Sandrine, Peppelenbosch Maikel P., Spek C. Arnold Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis Molecular medicine (Cambridge, Mass.) 2014;20:410-416 [PubMed]
  • Blok Dana C., van Lieshout Miriam H. P., Hoogendijk Arie J., Florquin Sandrine, de Boer Onno J., Garlanda Cecilia, Mantovani Alberto, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae Journal of innate immunity 2014;6 (4):542-552 [PubMed]
  • ten Berge Ineke, Heutinck Kirstin, Yapici Unsal, Stokman Geurt, Florquin Sandrine, van Kooten Cees, Garcia-Romo G., Ruben Jurjen, van de Vrie Mathijs, Hilbrands Luuk, Michelo Clive, Joosten Irma, van den Heuvel Heleen, Claas Frans The interplay between antiviral immunity and allo-immune reactivity after renal transplantation Consortium between the Centres Amsterdam, Leiden and Nijmegen (ALLOVIR) Transplant immunology 2014;31 (4):191-194 [PubMed]
  • Oosterveld M. J. S., Florquin S., van den Bergh Weerman M., Vogt L. The zebra among horses: extensive abnormalities in a kidney biopsy without clinical signs of kidney disease. Fabry's disease Netherlands journal of medicine 2014;72 (6):331, 335-335 [PubMed]
  • Hommes Tijmen J., Hoogendijk Arie J., Dessing Mark C., van't Veer Cornelis, Florquin Sandrine, Colonna Marco, de Vos Alex F., van der Poll Tom Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia Journal of pathology 2014;233 (4):357-367 [PubMed]
  • Smid B. E., van der Tol L., Cecchi F., Elliott P. M., Hughes D. A., Linthorst G. E., Timmermans J., Weidemann F., West M. L., Biegstraaten M., Lekanne Deprez R. H., Florquin S., Postema P. G., Tomberli B., van der Wal A. C., van den Bergh Weerman M. A., Hollak C. E. Uncertain diagnosis of Fabry disease: consensus recommendation on diagnosis in adults with left ventricular hypertrophy and genetic variants of unknown significance International journal of cardiology 2014;177 (2):400-408 [PubMed]

2013

  • Duitman J., Teske G. J. D., Butter L. M., Leemans J. C., Florquin S., Spek C. A. CCAAT/enhancer-binding protein delta (C/EBPδ) plays a minor role in renal host defense against uropathogenic Escherichia coli Transplant infectious disease 2013;15 (3):E119-E121 [PubMed]
  • Duitman Janwillem, Schouten Marcel, Groot Angelique P., Borensztajn Keren S., Daalhuisen Joost B., Florquin Sandrine, van der Poll Tom, Spek C. Arnold CCAAT/enhancer-binding protein delta facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner (vol 109, pg 9113, 2012) Proceedings of the National Academy of Sciences of the United States of America 2013;110 (37):15163 [PubMed]
  • Rampanelli Elena, Dessing Mark C., Claessen Nike, Teske Gwendoline J. D., Joosten Sander P. J., Pals Steven T., Leemans Jaklien C., Florquin Sandrine CD44-deficiency attenuates the immunologic responses to LPS and delays the onset of endotoxic shock-induced renal inflammation and dysfunction PLoS ONE 2013;8 (12):e84479 [PubMed]
  • Rampanelli Elena, Rouschop Kasper, Teske Gwendoline J. D., Claessen Nike, Leemans Jaklien C., Florquin Sandrine CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy American journal of physiology. Renal physiology 2013;305 (10):F1445-F1454 [PubMed]
  • Baas Marije C., Kers Jesper, Florquin Sandrine, de Fijter Johan W., van der Heide Jaap J. Homan, van den Bergh Weerman Marius A., ten Berge Ineke J. M., Bemelman Frederike J. Cyclosporine versus everolimus: effects on the glomerulus Clinical transplantation 2013;27 (4):535-540 [PubMed]
  • Kers J., Florquin S. Eosinophil-targeted therapy: not the panacea for antibody-mediated rejection? American journal of transplantation 2013;13 (10):2522-2523 [PubMed]
  • Schreinemachers M.-C. J. M., Bemelman F. J., Idu M. M., van Donselaar-van der Pant K. A. M. I., van de Berg P. J. E. J., Reitsma J. B., Legemate D. A., Florquin S., ten Berge I. J. M., Doorschodt B. M., van Gulik T. M. First clinical experience with polysol solution: pilot study in living kidney transplantation Transplantation proceedings 2013;45 (1):38-45 [PubMed]
  • Achouiti Ahmed, van der Meer Anne Jan, Florquin Sandrine, Yang Huan, Tracey Kevin J., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia Critical care (London, England) 2013;17 (6):R296 [PubMed]
  • Blok Dana C., van der Sluijs Koenraad F., Florquin Sandrine, de Boer Onno J., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia PLoS ONE 2013;8 (3):e58191 [PubMed]
  • Achouiti Ahmed, de Vos Alex F., de Beer Regina, Florquin Sandrine, van 't Veer Cornelis, van der Poll Tom Limited role of the receptor for advanced glycation end products during Streptococcus pneumoniae bacteremia Journal of innate immunity 2013;5 (6):603-612 [PubMed]
  • van Aalderen M. C., Yapici Ü, van der Pol J. A., de Reijke T. M., van Donselaar-van der Pant K. A. M. I., Florquin S., Bemelman F. J., ten Berge I. J. M. Polyomavirus BK in the pathogenesis of bladder cancer Netherlands journal of medicine 2013;71 (1):26-28 [PubMed]
  • Lattenist Lionel, Kers Jesper, Claessen Nike, ten Berge Ineke J. M., Bemelman Frederike J., Florquin Sandrine, Roelofs Joris J. T. H. Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection PLoS ONE 2013;8 (5):e64994 [PubMed]
  • Blok Dana C., de Vos Alex F., Florquin Sandrine, van der Poll Tom Role of interleukin 1 receptor like 1 (ST2) in gram-negative and gram-positive sepsis in mice Shock (Augusta, Ga.) 2013;40 (4):290-296 [PubMed]
  • Tammaro Alessandra, Stroo Ingrid, Rampanelli Elena, Blank Froilan, Butter Loes M., Claessen Nike, Takai Toshiyuki, Colonna Marco, Leemans Jaklien C., Florquin Sandrine, Dessing Mark C. Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy PLoS ONE 2013;8 (12):e82498 [PubMed]
  • Baas Marije C., Gerdes Victor E. A., ten Berge Ineke J. M., Heutinck K. M., Florquin S., Meijers Joost C. M., Bemelman Frederike J. Treatment with everolimus is associated with a procoagulant state Thrombosis research 2013;132 (2):307-311 [PubMed]

2012

  • Meijer-Jorna Lorine B. Angiogenesis in congenital vascular malformations - a dynamic view on a static lesion - 2012. 197p. ISBN 9789461908865. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin S., van der Horst C. M. A. M.; Co-supervisor: van der Wal A. C.)
  • Duitman Janwillem, Hoogendijk Arie J., Groot Angelique P., Ruela de Sousa Roberta R., van der Poll Tom, Florquin Sandrine, Spek C. Arnold CCAAT-Enhancer Binding Protein Delta (C/EBP delta) Protects Against Klebsiella pneumoniae-Induced Pulmonary Infection: Potential Role for Macrophage Migration Journal of infectious diseases 2012;206 (12):1826-1835 [PubMed]
  • Duitman Janwillem, Schouten Marcel, Groot Angelique P., Daalhuisen Joost B., Florquin Sandrine, van der Poll Tom, Spek C. Arnold CCAAT/enhancer-binding protein delta facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner Proceedings of the National Academy of Sciences of the United States of America 2012;109 (23):9113-9118 [PubMed]
  • van de Berg P. J. E. J., Yong S. L., Koch S. D., Lardy N., van Donselaar-van der Pant K. A. M. I., Florquin S., Bemelman F. J., van Lier R. A. W., ten Berge I. J. M. Characteristics of alloreactive T cells measured before renal transplantation Clinical and experimental immunology 2012;168 (2):241-250 [PubMed]
  • van de Berg Pablo J. E. J., Hoevenaars Eveline C., Yong Si-La, van Donselaar-van der Pant Karlijn A. M. I., van Tellingen Anne, Florquin Sandrine, van Lier René A. W., Bemelman Fréderike J., ten Berge Ineke J. M. Circulating lymphocyte subsets in different clinical situations after renal transplantation Immunology 2012;136 (2):198-207 [PubMed]
  • Tonneijck L., Florquin S., Korte M. R., Schut N. H. Fibrosing Pericarditis in a Patient with Encapsulating Peritoneal Sclerosis Peritoneal dialysis international 2012;32 (6):660-662 [PubMed]
  • Hoogerwerf Jacobien J., van der Windt Gerritje J. W., Blok Dana C., Hoogendijk Arie J., de Vos Alex F., van 't Veer Cornelis, Florquin Sandrine, Kobayashi Koichi S., Flavell Richard A., van der Poll Tom Interleukin-1 Receptor-Associated Kinase M-Deficient Mice Demonstrate an Improved Host Defense during Gram-negative Pneumonia Molecular medicine (Cambridge, Mass.) 2012;18 (7):1067-1075 [PubMed]
  • van der Windt Gerritje J. W., Blok Dana C., Hoogerwerf Jacobien J., Lammers Adriana J. J., de Vos Alex F., van't Veer Cornelis, Florquin Sandrine, Kobayashi Koichi S., Flavell Richard A., van der Poll Tom Interleukin 1 Receptor-Associated Kinase M Impairs Host Defense During Pneumococcal Pneumonia Journal of infectious diseases 2012;205 (12):1849-1857 [PubMed]
  • Stroo Ingrid Mechanisms of renal injury and repair. Role of stem cells, chemokines and the nodosome 2012. 175p. ISBN 9789090264943. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Leemans J. C.)
  • Achouiti Ahmed, Vogl Thomas, Urban Constantin F., Röhm Marc, Hommes Tijmen J., van Zoelen Marieke A. D., Florquin Sandrine, Roth Johannes, van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis PLoS pathogens 2012;8 (10):e1002987 [PubMed]
  • Pulskens Wilco P. C. Pattern recognition receptors, sensing re(n)al danger 2012. 203p. ISBN 9789090266664. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisor: Leemans J. C.)
  • Stroo Ingrid, Butter Loes M., Claessen Nike, Teske Gwen J., Rubino Stephen J., Girardin Stephen E., Florquin Sandrine, Leemans Jaklien C. Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease Biology open 2012;1 (12):1239-1247 [PubMed]
  • Aslami H., Haitsma J. J., Hofstra J. J., Florquin S., Dos Santos C., Streutker C., Zhang H., Levi M. [=Marcel M.], Slutsky A. S., Schultz M. J. Plasma-derived human antithrombin attenuates ventilator-induced coagulopathy but not inflammation in a Streptococcus pneumoniae pneumonia model in rats Journal of thrombosis and haemostasis 2012;10 (3):399-410 [PubMed]
  • Kager Liesbeth M., van der Windt Gerritje J. W., Wieland Catharina W., Florquin Sandrine, van 't Veer Cornelis, van der Poll Tom Plasminogen activator inhibitor type I may contribute to transient, non-specific changes in immunity in the subacute phase of murine tuberculosis Microbes and infection / Institut Pasteur 2012;14 (9):748-755 [PubMed]
  • Meijer-Jorna Lorine B., van der Loos Chris M., Teeling Peter, de Boer Onno J., Florquin Sandrine, van der Horst Chantal M. A. M., van der Wal Allard C. Proliferation and maturation of microvessels in arteriovenous malformations - expression patterns of angiogenic and cell cycle-dependent factors Journal of cutaneous pathology 2012;39 (6):610-620 [PubMed]
  • Dessing Mark C., Pulskens Wilco P., Teske Gwendoline J., Butter Loes M., van der Poll Tom, Yang Huan, Tracey Kevin J., Nawroth Peter P., Bierhaus Angelika, Florquin Sandrine, Leemans Jaklien C. RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury Journal of innate immunity 2012;4 (1):80-85 [PubMed]
  • van Zoelen Marieke A. D., Wieland Catharina W., van der Windt Gerritje J. W., Florquin Sandrine, Nawroth Peter P., Bierhaus Angelika, van der Poll Tom Receptor for advanced glycation end products is protective during murine tuberculosis Molecular immunology 2012;52 (3-4):183-189 [PubMed]
  • Heutinck Kirstin M., Kassies Jorien, Florquin Sandrine, ten Berge Ineke J. M., Hamann Jörg, Rowshani Ajda T. SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I Nephrology, dialysis, transplantation 2012;27 (7):2746-2754 [PubMed]
  • Yapici Ü, Roelofs J. J. T. H., Florquin S. The Importance of Testing Anti-IL-17 Antibodies From Different Suppliers American journal of transplantation 2012;12 (2):504-505 [PubMed]
  • Lammers Adriana J. J., de Porto Alexander P. N. A., de Boer Onno J., Florquin Sandrine, van der Poll Tom The role of TLR2 in the host response to pneumococcal pneumonia in absence of the spleen BMC infectious diseases 2012;12 (1):139 [PubMed]
  • Leemans Jaklien C., Butter Loes M., Teske Gwendoline J. D., Stroo Ingrid, Pulskens Wilco P., Florquin Sandrine The Toll Interleukin-1 Receptor (IL-1R) 8/Single Ig Domain IL-1R-Related Molecule Modulates the Renal Response to Bacterial Infection Infection and immunity 2012;80 (11):3812-3820 [PubMed]
  • Heutinck Kirstin M., Rowshani Ajda T., Kassies Jorien, Claessen Nike, van Donselaar-van der Pant Karlijn A. M. I., Bemelman Fréderike J., Eldering Eric, van Lier René A. W., Florquin Sandrine, ten Berge Ineke J. M., Hamann Jörg Viral double-stranded RNA sensors induce antiviral, pro-inflammatory, and pro-apoptotic responses in human renal tubular epithelial cells Kidney international 2012;82 (6):664-675 [PubMed]

2011

  • Wösten-van Asperen Roelie M., Lutter René, Specht Patricia A., Moll Gert N., van Woensel Job B., van der Loos Chris M., van Goor Harry, Kamilic Jelena, Florquin Sandrine, Bos Albert P. Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist Journal of pathology 2011;225 (4):618-627 [PubMed]
  • van der Windt Gerritje J. W., Schouten Marcel, Zeerleder Sacha, Florquin Sandrine, van der Poll Tom CD44 Is Protective during Hyperoxia-Induced Lung Injury American journal of respiratory cell and molecular biology 2011;44 (3):377-383 [PubMed]
  • van 't Veer Cornelis, van den Pangaart Petra S., Kruijswijk Daniëlle, Florquin Sandrine, de Vos Alex F., van der Poll Tom Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli Journal of biological chemistry 2011;286 (42):36603-36618 [PubMed]
  • van Zoelen Marieke A. D., Verstege Marleen I., Draing Christian, de Beer Regina, Veer Cornelis Van't, Florquin Sandrine, Bresser Paul, van der Zee Jaring S., te Velde Anje A., von Aulock Sonja, van der Poll Tom Endogenous MCP-1 promotes lung inflammation induced by LPS and LTA Molecular immunology 2011;48 (12-13):1468-1476 [PubMed]
  • Lammers Adriana J., de Porto Alexander P., Florquin Sandrine, de Boer Onno J., Bootsma Hester J., Hermans Peter W., van der Poll Tom Enhanced vulnerability for Streptococcus pneumoniae sepsis during asplenia is determined by the bacterial capsule Immunobiology 2011;216 (8):863-870 [PubMed]
  • Doorschodt B. M., Schreinemachers M. C. J. M., Behbahani M., Florquin S., Weis J., Staat M., Tolba R. H. Hypothermic Machine Perfusion of Kidney Grafts: Which Pressure is Preferred? Annals of biomedical engineering 2011;39 (3):1051-1059 [PubMed]
  • Yapici Ünsal, Kers Jesper, Bemelman Fréderike J., Roelofs Joris J. T. H., Groothoff Jaap W., van der Loos Chris M., van Donselaar-van der Pant Karlijn A. M. I., Idu Mirza M., Claessen Nike, ten Berge Ineke J. M., Florquin Sandrine Interleukin-17 positive cells accumulate in renal allografts during acute rejection and are independent predictors of worse graft outcome Transplant international 2011;24 (10):1008-1017 [PubMed]
  • Hoogerwerf Jacobien J., Leendertse Masja, Wieland Catharina W., de Vos Alex F., de Boer J. Daan, Florquin Sandrine, van der Poll Tom Loss of Suppression of Tumorigenicity 2 (ST2) Gene Reverses Sepsis-induced Inhibition of Lung Host Defense in Mice American journal of respiratory and critical care medicine 2011;183 (7):932-940 [PubMed]
  • van der Windt Gerritje J. W., Hoogendijk Arie J., Schouten Marcel, Hommes Tijmen J., de Vos Alex F., Florquin Sandrine, van der Poll Tom Osteopontin Impairs Host Defense During Pneumococcal Pneumonia Journal of infectious diseases 2011;203 (12):1850-1858 [PubMed]
  • de Boer Onno J., Teeling Peter, Jansen Marcel, Ploegmakers Hanneke, van der Loos Chris M., Kummer J. Alain, Florquin Sandrine, van der Wal Allard C. Spatial Differences in the Presence of FOXP3(+) and GranzymeB(+) T Cells between the Intra- and Extravascular Compartments in Renal Allograft Vasculopathy PLoS ONE 2011;6 (4):e18656 [PubMed]
  • van der Windt Gerritje J. W., Hoogendijk Arie J., de Vos Alex F., Kerver Marjolein E., Florquin Sandrine, van der Poll Tom The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia Laboratory investigation; a journal of technical methods and pathology 2011;91 (4):588-597 [PubMed]

2010

  • van der Windt Gerritje J. W., van 't Veer Cornelis, Florquin Sandrine, van der Poll Tom CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages Infection and immunity 2010;78 (1):115-124 [PubMed]
  • van der Windt Gerritje J. W., Florquin Sandrine, de Vos Alex F., van't Veer Cornelis, Queiroz Karla C. S., Liang Jiurong, Jiang Dianhua, Noble Paul W., van der Poll Tom CD44 Deficiency Is Associated with Increased Bacterial Clearance but Enhanced Lung Inflammation During Gram-Negative Pneumonia American journal of pathology 2010;177 (5):2483-2494 [PubMed]
  • Stroo Ingrid, Stokman Geurt, Teske Gwen J. D., Raven Anje, Butter Loes M., Florquin Sandrine, Leemans Jaklien C. Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase International immunology 2010;22 (6):433-442 [PubMed]
  • Wiersinga W. Joost, Calandra Thierry, Kager Liesbeth M., van der Windt Gerritje J. W., Roger Thierry, le Roy Didier, Florquin Sandrine, Peacock Sharon J., Sweep Fred C. G. J., van der Poll Tom Expression and Function of Macrophage Migration Inhibitory Factor (MIF) in Melioidosis PLoS neglected tropical diseases 2010;4 (2):e605 [PubMed]
  • Dessing Mark C., Bemelman Frederike J., Claessen Nike, ten Berge Ineke J. M., Florquin Sandrine, Leemans Jaklien C. Intragraft Toll-like receptor profiling in acute renal allograft rejection Nephrology, dialysis, transplantation 2010;25 (12):4087-4092 [PubMed]
  • Kers Jesper, Xu-Dubois Yi-Chun, Rondeau Eric, Claessen Nike, Idu Mirza M., Roelofs Joris J. T. H., Bemelman Fréderike J., ten Berge Ineke J. M., Florquin Sandrine Intragraft Tubular Vimentin and CD44 Expression Correlate With Long-Term Renal Allograft Function and Interstitial Fibrosis and Tubular Atrophy Transplantation 2010;90 (5):502-509 [PubMed]
  • van Zoelen Marieke A. D., Achouiti Ahmed, Schmidt Ann-Marie, Yang Huan, Florquin Sandrine, Tracey Kevin J., van der Poll Tom Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis Critical care medicine 2010;38 (6):1414-1422 [PubMed]
  • van der Windt Gerritje J. W., Wiersinga W. Joost, Wieland Catharina W., Tjia Ivo C. S. I., Day Nicholas P., Peacock Sharon J., Florquin Sandrine, van der Poll Tom Osteopontin Impairs Host Defense during Established Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis) PLoS neglected tropical diseases 2010;4 (8):e806 [PubMed]
  • van der Windt G. J. W., Hoogerwerf J. J., de Vos A. F., Florquin S., van der Poll T. Osteopontin promotes host defense during Klebsiella pneumoniae-induced pneumonia European respiratory journal 2010;36 (6):1337-1345 [PubMed]
  • Schreinemachers Marie-Claire J. M. Preclinical evvaluation of a new organ preservation solution 2010. 183p. ISBN 9789090253596. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin S., Tolba R.; Co-supervisor: Bemelman F. J.)
  • Schreinemachers M. C. J. M., Doorschodt B. M., Florquin S., van den Bergh Weerman M. A., Zernecke A., Idu M. M., Tolba R. H., van Gulik T. M. Pulsatile perfusion preservation of warm ischaemia-damaged experimental kidney grafts British journal of surgery 2010;97 (3):349-358 [PubMed]
  • Dessing Mark C., Butter Loes M., Teske Gwendoline J., Claessen Nike, van der Loos Chris M., Vogl Thomas, Roth Johannes, van der Poll Tom, Florquin Sandrine, Leemans Jaklien C. S100A8/A9 Is Not Involved in Host Defense against Murine Urinary Tract Infection PLoS ONE 2010;5 (10):e13394 [PubMed]
  • Stokman Geurt, Stroo Ingrid, Claessen Nike, Teske Gwendoline J. D., Florquin Sandrine, Leemans Jaklien C. SDF-1 provides morphological and functional protection against renal ischaemia/reperfusion injury Nephrology, dialysis, transplantation 2010;25 (12):3852-3859 [PubMed]
  • Stokman Geurt, Stroo Ingrid, Claessen Nike, Teske Gwendoline J. D., Weening Jan J., Leemans Jaklien C., Florquin Sandrine Stem Cell Factor Expression after Renal Ischemia Promotes Tubular Epithelial Survival PLoS ONE 2010;5 (12):e14386 [PubMed]
  • Coppo Rosanna, Troyanov Stéphan, Camilla Roberta, Hogg Ronald J., Cattran Daniel C., Cook H. Terence, Feehally John, Roberts Ian S. D., Amore Alessandro, Alpers Charles E., Barratt Jonathan, Berthoux Francois, Bonsib Stephen, Bruijn Jan A., D'Agati Vivette, D'Amico Giuseppe, Emancipator Steven N., Emma Francesco, Ferrario Franco, Fervenza Fernando C., Florquin Sandrine, Fogo Agnes B., Geddes Colin C., Groene Hermann J., Haas Mark, Herzenberg Andrew M., Hill Prue A., Hsu Stephen I., Jennette J. Charles, Joh Kensuke, Julian Bruce A., Kawamura Tetsuya, Lai Fernand M., Li Lei S., Li Philip K., Liu Zhi H., Mezzano Sergio, Schena F. Paolo, Tomino Yasuhiko, Walker Patrick D., Wang Haiyan, Weening Jan J., Yoshikawa Norishige, Zhang Hong The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults Kidney international 2010;77 (10):921-927 [PubMed]
  • van der Meer Jelger J. The role of inflammation and infection in the pathogenesis of atheroclerosis 2010. 129p. ISBN 9789090250786. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Florquin S.; Co-supervisors: van der Wal A. C., de Boer O. J.)
  • Pulskens Wilco P., Rampanelli Elena, Teske Gwendoline J., Butter Loes M., Claessen Nike, Luirink Ilse K., Poll Tom van der, Florquin Sandrine, Leemans Jaklien C. TLR4 Promotes Fibrosis but Attenuates Tubular Damage in Progressive Renal Injury Journal of the American Society of Nephrology 2010;21 (8):1299-1308 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, van der Poll Tom Toll-like receptor 9 is not important for host defense against Haemophilus influenzae Immunobiology 2010;215 (11):910-914 [PubMed]
  • Cox-Brinkman Josanne, van den Bergh Weerman Marius A., Wijburg Frits A., Aerts Johannes M. F. G., Florquin Sandrine, van der Lee Johanna H., Hollak Carla E. M. Ultrastructural Analysis of Dermal Fibroblasts in Mucopolysaccharidosis Type I: Effects of Enzyme Replacement Therapy and Hematopoietic Cell Transplantation Ultrastructural pathology 2010;34 (3):126-132 [PubMed]
  • van Ham S. Marieke, Heutinck Kirstin M., Jorritsma Tineke, Bemelman Fréderike J., Strik Merel C. M., Vos Wim, Muris Jettie J. F., Florquin Sandrine, ten Berge Ineke J. M., Rowshani Ajda T. Urinary granzyme A mRNA is a biomarker to diagnose subclinical and acute cellular rejection in kidney transplant recipients Kidney international 2010;78 (10):1033-1040 [PubMed]
  • Wösten-van Asperen Roelie M., Lutter René, Specht Patricia A. C., van Woensel Job B., van der Loos Chris M., Florquin Sandrine, Lachmann Burkhard, Bos Albert P. Ventilator-Induced Inflammatory Response in Lipopolysaccharide-Exposed Rat Lung Is Mediated by Angiotensin-Converting Enzyme American journal of pathology 2010;176 (5):2219-2227 [PubMed]

2009

  • Leendertse Masja, Willems Rob J., Giebelen Ida A., Florquin Sandrine, van den Pangaart Petra S., Bonten Marc J., van der Poll Tom Cecal ligation and puncture induced sepsis impairs host defense against Enterococcus faecium peritonitis Intensive care medicine 2009;35 (5):924-932 [PubMed]
  • Schreinemachers M. C. J. M., Doorschodt B. M., Florquin S., Tolba R. H. Comparison of Preservation Solutions for Washout of Kidney Grafts: An Experimental Study Transplantation proceedings 2009;41 (10):4072-4079 [PubMed]
  • Schut E. S., Brouwer M. C., de Gans J., Florquin S., Troost D., van de Beek D. Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis Neurology 2009;73 (23):1988-1995 [PubMed]
  • Roelofs Joris J. T. H., Rouschop Kasper M. A., Teske Gwendoline J. D., Wagenaar Gerry T. M., Claessen Nike, Weening Jan J., van der Poll Tom, Florquin Sandrine Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection Nephrology, dialysis, transplantation 2009;24 (3):801-808 [PubMed]
  • Doorschodt Benedict M., Schreinemachers Marie-Claire J. M., Florquin Sandrine, Lai Wei, Sitzia Mario, Zernecke Alma, Tolba Rene H. Evaluation of a novel system for hypothermic oxygenated pulsatile perfusion preservation International journal of artificial organs 2009;32 (10):728-738 [PubMed]
  • van Zoelen Marieke A. D., Vogl Thomas, Foell Dirk, van Veen Suzanne Q., van Till Jan W. O., Florquin Sandrine, Tanck Michael W., Wittebole Xavier, Laterre Pierre-François, Boermeester Marja A., Roth Johannes, van der Poll Tom Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental Sepsis American journal of respiratory and critical care medicine 2009;180 (11):1098-1106 [PubMed]
  • Stroo Ingrid, Stokman Geurt, Teske Gwendoline J. D., Florquin Sandrine, Leemans Jaklien C. Haematopoietic stem cell migration to the ischemic damaged kidney is not altered by manipulating the SDF-1/CXCR4-axis Nephrology, dialysis, transplantation 2009;24 (7):2082-2088 [PubMed]
  • Bos Eelke M., Leuvenink Henri G. D., Snijder Pauline M., Kloosterhuis Niels J., Hillebrands Jan-Luuk, Leemans Jaklien C., Florquin Sandrine, van Goor Harry Hydrogen Sulfide-Induced Hypometabolism Prevents Renal Ischemia/Reperfusion Injury Journal of the American Society of Nephrology 2009;20 (9):1901-1905 [PubMed]
  • Schreinemachers Marie-Claire J. M., Doorschodt Benedict M., Florquin Sandrine, van den Bergh Weerman Marius A., Reitsma Johannes B., Lai Wei, Sitzia Mario, Minor Thomas M., Tolba Rene H., van Gulik Thomas M. Improved preservation and microcirculation with POLYSOL after transplantation in a porcine kidney autotransplantation model Nephrology, dialysis, transplantation 2009;24 (3):816-824 [PubMed]
  • Schreinemachers M. C. J. M., Doorschodt B. M., Florquin S., Idu M. M., Tolba R. H., van Gulik T. M. Improved renal function of warm ischemically damaged kidneys using polysol Transplantation proceedings 2009;41 (1):32-35 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Oei G. Anneke, Florquin Sandrine, Bonten Marc J. M., van der Poll Tom Intestinal Enterococcus faecium Colonization Improves Host Defense during Polymicrobial Peritonitis Journal of infectious diseases 2009;200 (5):735-744 [PubMed]
  • Yapici Unsal, Bemelman Fréderike J., Scheepstra Cornelis G., Roelofs Joris J. T. H., Claessen Nike, van der Loos Chris, van Donselaar-van der Pant Karlijn, Bouts Antonia H. M., Idu Mirza M., Rowshani Ajda T., ten Berge Ineke J. M., Florquin Sandrine Intragraft FOXP3 Protein or mRNA During Acute Renal Allograft Rejection Correlates With Inflammation, Fibrosis, and Poor Renal Outcome Transplantation 2009;87 (9):1377-1380 [PubMed]
  • Florquin S. Membranoproliferatieve glomerulonefritisin: I.M. Bajema, J.A. Bruijn, editors. Praktische Nefropathologie 2009. Leiden: s.n.; 2009. p. 49-62, ISBN 9789067676717
  • Baas M. C., van Donselaar K. A. M. I., Florquin S., van Binnendijk R. S., ten Berge I. J. M., Bemelman F. J. Mumps: Not an Innocent Bystander in Solid Organ Transplantation American journal of transplantation 2009;9 (9):2186-2189 [PubMed]
  • Iyer Shankar S., Pulskens Wilco P., Sadler Jeffrey J., Butter Loes M., Teske Gwendoline J., Ulland Tyler K., Eisenbarth Stephanie C., Florquin Sandrine, Flavell Richard A., Leemans Jaklien C., Sutterwala Fayyaz S. Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome Proceedings of the National Academy of Sciences of the United States of America 2009;106 (48):20388-20393 [PubMed]
  • van der Windt Gerritje J. W., Wieland Catharina W., Wiersinga Willem J., Florquin Sandrine, van der Poll Tom Osteopontin is not crucial to protective immunity during murine tuberculosis Immunology 2009;128 (1 Suppl):e766-e776 [PubMed]
  • Roelofs Joris J. T. H., Teske Gwendoline J. D., Bonta Peter I., de Vries Carlie J. M., Meijers Joost C. M., Weening Jan J., van der Poll Tom, Florquin Sandrine Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis Kidney international 2009;75 (1):52-59 [PubMed]
  • van Zoelen Marieke A. D., Schmidt Ann-Marie, Florquin Sandrine, Meijers Joost C., de Beer Regina, de Vos Alex F., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom Receptor for Advanced Glycation End Products Facilitates Host Defense during Escherichia coli-Induced Abdominal Sepsis in Mice Journal of infectious diseases 2009;200 (5):765-773 [PubMed]
  • van Zoelen M. A. D., Schmidt A.-M., Florquin S. Receptor for advanced glycation end products facilitates host defense during Escherichia coli-induced abdominal sepsis in mice (vol 200, pg 765, 2009) Journal of infectious diseases 2009;200 (10):1629
  • van Zoelen Marieke A. D., van der Sluijs Koenraad F., Achouiti Achmed, Florquin Sandrine, Braun-Pater Jennie M., Yang Huan, Nawroth Peter P., Tracey Kevin J., Bierhaus Angelika, van der Poll Tom Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia Virology 2009;391 (2):265-273 [PubMed]
  • van Zoelen Marieke A. D., Yang Huan, Florquin Sandrine, Meijers Joost C. M., Akira Shizuo, Arnold Bernd, Nawroth Peter P., Bierhaus Angelika, Tracey Kevin J., van der Poll Tom Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo Shock (Augusta, Ga.) 2009;31 (3):280-284 [PubMed]
  • Wieland Catharina W., van der Windt Gerritje J. W., Florquin Sandrine, McKenzie Andrew N. J., van der Poll Tom ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis Microbes and infection / Institut Pasteur 2009;11 (4):524-530 [PubMed]
  • Giebelen I. A. J., Leendertse M., Florquin S., van der Poll T. Stimulation of acetylcholine receptors impairs host defence during pneumococcal pneumonia European respiratory journal 2009;33 (2):375-381 [PubMed]
  • Roberts Ian S. D., Cook H. Terence, Troyanov Stéphan, Alpers Charles E., Amore Alessandro, Barratt Jonathan, Berthoux Francois, Bonsib Stephen, Bruijn Jan A., Cattran Daniel C., Coppo Rosanna, D'Agati Vivette, D'Amico Giuseppe, Emancipator Steven, Emma Francesco, Feehally John, Ferrario Franco, Fervenza Fernando C., Florquin Sandrine, Fogo Agnes, Geddes Colin C., Groene Hermann-Josef, Haas Mark, Herzenberg Andrew M., Hill Prue A., Hogg Ronald J., Hsu Stephen I., Jennette J. Charles, Joh Kensuke, Julian Bruce A., Kawamura Tetsuya, Lai Fernand M., Li Lei-Shi, Li Philip K. T., Liu Zhi-Hong, Mackinnon Bruce, Mezzano Sergio, Schena F. Paolo, Tomino Yasuhiko, Walker Patrick D., Wang Haiyan, Weening Jan J., Yoshikawa Nori, Zhang Hong The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility Kidney international 2009;76 (5):546-556 [PubMed]
  • Cattran Daniel C., Coppo Rosanna, Cook H. Terence, Feehally John, Roberts Ian S. D., Troyanov Stéphan, Alpers Charles E., Amore Alessandro, Barratt Jonathan, Berthoux Francois, Bonsib Stephen, Bruijn Jan A., D'Agati Vivette, D'Amico Giuseppe, Emancipator Steven, Emma Francesco, Ferrario Franco, Fervenza Fernando C., Florquin Sandrine, Fogo Agnes, Geddes Colin C., Groene Hermann-Josef, Haas Mark, Herzenberg Andrew M., Hill Prue A., Hogg Ronald J., Hsu Stephen I., Jennette J. Charles, Joh Kensuke, Julian Bruce A., Kawamura Tetsuya, Lai Fernand M., Leung Chi Bon, Li Lei-Shi, Li Philip K. T., Liu Zhi-Hong, Mackinnon Bruce, Mezzano Sergio, Schena F. Paolo, Tomino Yasuhiko, Walker Patrick D., Wang Haiyan, Weening Jan J., Yoshikawa Nori, Zhang Hong The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification Kidney international 2009;76 (5):534-545 [PubMed]
  • van Zoelen Marieke A. D., Schouten Marcel, de Vos Alex F., Florquin Sandrine, Meijers Joost C. M., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom The Receptor for Advanced Glycation End Products Impairs Host Defense in Pneumococcal Pneumonia Journal of immunology (Baltimore, Md. 2009;182 (7):4349-4356 [PubMed]
  • Leemans Jaklien C., Butter Loes M., Pulskens Wilco P. C., Teske Gwendoline J. D., Claessen Nike, van der Poll Tom, Florquin Sandrine The Role of Toll-Like Receptor 2 in Inflammation and Fibrosis during Progressive Renal Injury PLoS ONE 2009;4 (5):e5704 [PubMed]
  • Stegenga Michiel E., Florquin Sandrine, de Vos Alex F., van der Poll Tom The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice Critical care medicine 2009;37 (2):614-618 [PubMed]
  • Roelofs Joris J., Florquin Sandrine Tubulointerstitial Injury in IgA Nephropathyin: K. N. Lai, editors. Recent Advances in IgA Nephropathy. Hong Kong, China: World Scientific Publishing Co. Pte. Ltd.; 2009. p. 55-68, ISBN 9789812835864
  • Florquin S. Tubulo-interstitiële nefritisin: I.M. Bajema, J.A. Bruijn, editors. Praktische Nefropathologie 2009. Leiden: s.n.; 2009. p. 179-196, ISBN 9789067676717
  • van Zoelen Marieke A. D., Florquin Sandrine, de Beer Regina, Pater Jennie M., Verstege Marleen I., Meijers Joost C. M., van der Poll Tom Urokinase Plasminogen Activator Receptor-Deficient Mice Demonstrate Reduced Hyperoxia-Induced Lung Injury American journal of pathology 2009;174 (6):2182-2189 [PubMed]

2008

  • Wösten-van Asperen R. M., Lutter R., Haitsma J. J., Merkus M. P., van Woensel J. B., van der Loos C. M., Florquin S., Lachmann B., Bos A. P. ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin European respiratory journal 2008;31 (2):363-371 [PubMed]
  • Renckens Rosemarijn, van Westerloo David J., Roelofs Joris J. T. H., Pater Jennie M., Schultz Marcus J., Florquin Sandrine, van der Poll Tom Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice Critical care medicine 2008;36 (2):580-587 [PubMed]
  • Choi Goda, Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., Rijneveld Anita W., Bresser Paul, van der Zee Jaring S., Florquin Sandrine, van der Poll Tom, Levi Marcel, Schultz Marcus J. Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats Critical care medicine 2008;36 (1):204-210 [PubMed]
  • Scheepstra Cornelis, Bemelman Fréderike J., van der Loos Chris, Rowshani Ajda T., van Donselaar-van der Pant Karlijn A. M. I., Idu Mirza M., ten Berge Ineke J. M., Florquin Sandrine B cells in cluster or in a scattered pattern do not correlate with clinical outcome of renal allograft rejection Transplantation 2008;86 (6):772-778 [PubMed]
  • Wieland Catharina W., van der Windt Gerritje J. W., Wiersinga W. Joost, Florquin Sandrine, van der Poll Tom CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis Immunology 2008;125 (2):272-279 [PubMed]
  • Giebelen Ilona A. J., Le Moine Alain, van den Pangaart Petra S., Sadis Claude, Goldman Michel, Florquin Sandrine, van der Poll Tom Deficiency of alpha7 cholinergic receptors facilitates bacterial clearance in Escherichia coli peritonitis Journal of infectious diseases 2008;198 (5):750-757 [PubMed]
  • Stokman Geurt, Leemans Jaklien C., Stroo Ingrid, Hoedemaeker Inge, Claessen Nike, Teske Gwendoline J. D., Weening Jan J., Florquin Sandrine Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis Nephrology, dialysis, transplantation 2008;23 (2):483-491 [PubMed]
  • Roelofs Joris J., Abramowicz Daniel, Florquin Sandrine Immunomodulators: interleukins, interferons, and IV immunoglobulinin: Marc E. De Broe, George A. Porter, William M. Bennett, Gilbert Deray, editors. Clinical Nephrotoxins - Renal Injury from Drugs and Chemicals, Third Edition. Springer; 2008. p. 683-698, ISBN 9780387848426
  • Grootscholten Cecile, Bajema Ingeborg M., Florquin Sandrine, Steenbergen Eric J., Peutz-Kootstra Carine J., Goldschmeding Roel, Bijl Marc, Hagen E. Christiaan, van Houwelingen Hans C., Derksen Ronald H. W. M., Berden Jo H. M. Interobserver agreement of scoring of histopathological characteristics and classification of lupus nephritis Nephrology, dialysis, transplantation 2008;23 (1):223-230 [PubMed]
  • Stokman Geurt Mechanisms of tubular damage and repair in renal injury 2008. 157p. ISBN 9789090231013. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin S., Weening J. J.; Co-supervisor: Leemans J. C.)
  • Florquin S. Membranoproliferatieve glomerulonefritisin: I.M. Bajema, J.A. Bruijn, editors. Praktische nefropathologie 2008. Leiden: Boerhaave Commissie vor Postacademisch Onderwijs in de Geneeskunde, Leids Universitair Medisch Centrum; 2008. p. 47-60, ISBN 9789067676427
  • Buonocore Sofia, Haddou Najate Ouled, Moore Fabrice, Florquin Sandrine, Paulart Frédéric, Heirman Carlo, Thielemans Kris, Goldman Michel, Flamand Véronique Neutrophil-dependent tumor rejection and priming of tumoricidal CD8+ T cell response induced by dendritic cells overexpressing CD95L Journal of leukocyte biology 2008;84 (3):713-720 [PubMed]
  • van Zoelen Marieke A. D., Florquin Sandrine, Meijers Joost C. M., de Beer Regina, de Vos Alex F., de Boer Onno J., van der Poll Tom Platelet-activating factor receptor contributes to host defense against Pseudomonas aeruginosa pneumonia but is not essential for the accompanying inflammatory and procoagulant response Journal of immunology (Baltimore, Md. 2008;180 (5):3357-3365 [PubMed]
  • Wösten-van Asperen Roelie M., Lutter Rene, Haitsma Jack J., Merkus Maruschka P., van Woensel Job B., Florquin Sandrine, Lachmann Burkhard, Bos Albert P. Pulmonary Angiotensin-converting Enzyme Mediates Ventilator-induced Lung Injury in Rats Proceedings of the American Thoracic Society 2008;5 (3):371 [PubMed]
  • Alegre Maria-Luisa, Leemans Jaklien, Le Moine Alain, Florquin Sandrine, de Wilde Virginie, Chong Anita, Goldman Michel The multiple facets of toll-like receptors in transplantation biology Transplantation 2008;86 (1):1-9 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., van den Pangaart Petra S., Wiersinga W. Joost, de Vos Alex F., Florquin Sandrine, Bonten Marc J. M., van der Poll Tom TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis Journal of immunology (Baltimore, Md. 2008;180 (7):4865-4874 [PubMed]
  • Dessing Mark C., Florquin Sandrine, Paton James C., van der Poll Tom Toll-like receptor 2 contributes to antibacterial defence against pneumolysin-deficient pneumococci Cellular microbiology 2008;10 (1):237-246 [PubMed]
  • Pulskens Wilco P., Teske Gwendoline J., Butter Loes M., Roelofs Joris J., van der Poll Tom, Florquin Sandrine, Leemans Jaklien C. Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury PLoS ONE 2008;3 (10):e3596 [PubMed]
  • Renckens R., Roelofs J. J. T. H., Stegenga M. E., Florquin S., Levi M. [=Marcel M.], Carmeliet P., van't Veer C., van der Poll T. Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia Journal of thrombosis and haemostasis 2008;6 (4):660-668 [PubMed]
  • Celie J. W. A. M., Reijmers R. M., Slot E. M., Beelen R. H. J., Spaargaren M., ter Wee P. M., Florquin S., van den Born J. Tubulointerstitial heparan sulfate proteoglycan changes in human renal diseases correlate with leukocyte influx and proteinuria American journal of physiology. Renal physiology 2008;294 (1):F253-F263 [PubMed]
  • Florquin S. Tubulo-interstitiële nefritisin: I.M. Bajema, J.A. Bruijn, editors. Praktische nefropathologie 2008. Leiden: Boerhaave Commissie vor Postacademisch Onderwijs in de Geneeskunde, Leids Universitair Medisch Centrum; 2008. p. 175-190, ISBN 9789067676427

2007

  • van Well Gijs Th. J., Wieland Catharina W., Florquin Sandrine, Roord John J., van der Poll Tom, van Furth A. Marceline A new murine model to study the pathogenesis of tuberculous meningitis Journal of infectious diseases 2007;195 (5):694-697 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Polfliet Machteld M. J., van den Berg Timo K., Dijkstra Christine D., Roord John J., Hack C. Erik, van Furth A. Marceline C1 inhibitor treatment improves host defense in pneumococcal meningitis in rats and mice Journal of infectious diseases 2007;196 (1):115-123 [PubMed]
  • Dessing Mark C., Knapp Sylvia, Florquin Sandrine, de Vos Alex F., van der Poll Tom CD14 facilitates invasive respiratory tract infection by Streptococcus pneumoniae American journal of respiratory and critical care medicine 2007;175 (6):604-611 [PubMed]
  • Dessing Mark C., van der Sluijs Koenraad F., Florquin Sandrine, van der Poll Tom CD14 plays a limited role during influenza A virus infection in vivo Immunology letters 2007;113 (1):47-51 [PubMed]
  • Alegre Maria-Luisa, Florquin Sandrine, Goldman Michel Cellular mechanisms underlying acute graft rejection: time for reassessment Current opinion in immunology 2007;19 (5):563-568 [PubMed]
  • Wiersinga W. Joost, Wieland Catharina W., van der Windt Gerritje J. W., de Boer Anita, Florquin Sandrine, Dondorp Arjen, Day Nicholas P., Peacock Sharon J., van der Poll Tom Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis Infection and immunity 2007;75 (8):3739-3746 [PubMed]
  • Dinant Sander, Vetelainen Reeta L., Florquin Sandrine, van Vliet Arlene K., van Gulik Thomas M. IL-10 attenuates hepatic I/R injury and promotes hepatocyte proliferation Journal of surgical research 2007;141 (2):176-182 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, van der Poll Tom Interleukin 18 participates in the early inflammatory response and bacterial clearance during pneumonia caused by nontypeable Haemophilus influenzae Infection and immunity 2007;75 (10):5068-5072 [PubMed]
  • Wieland Catharina W., Koppel Estella A., den Dunnen Jeroen, Florquin Sandrine, McKenzie Andrew N. J., van Kooyk Yvette, van der Poll Tom, Geijtenbeek Teunis B. H. Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis Microbes and infection / Institut Pasteur 2007;9 (2):134-141 [PubMed]
  • Dessing Mark C., van der Sluijs Koenraad F., Florquin Sandrine, van der Poll Tom Monocyte chemoattractant protein 1 contributes to an adequate immune response in influenza pneumonia Clinical immunology (Orlando, Fla.) 2007;125 (3):328-336 [PubMed]
  • Sadis Claude, Teske Gwen, Stokman Geurt, Kubjak Carole, Claessen Nike, Moore Fabrice, Loi Patrizia, Diallo Bilo, Barvais Luc, Goldman Michel, Florquin Sandrine, Le Moine Alain Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway PLoS ONE 2007;2 (5):e469 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Bonta Peter I., Florquin Sandrine, de Vries Carlie J. M., Levi Marcel, Carmeliet Peter, van't Veer Cornelis, van der Poll Tom Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia Blood 2007;109 (4):1593-1601 [PubMed]
  • Choi Goda, Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., Florquin Sandrine, Bresser Paul, Levi Marcel, van der Poll Tom, Schultz Marcus J. Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats Critical care medicine 2007;35 (5):1362-1368 [PubMed]
  • Celie Johanna W. A. M., Rutjes Niels W. P., Keuning Eelco D., Soininen Raija, Heljasvaara Ritva, Pihlajaniemi Taina, Dräger Angelika M., Zweegman Sonja, Kessler Floortje L., Beelen Robert H. J., Florquin Sandrine, Aten Jan, van den Born Jacob Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion American journal of pathology 2007;170 (6):1865-1878 [PubMed]
  • Roelofs J. J. T. H. The fibrinolytic system in renal disease 2007. 157p. ISBN 9789090219110. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin Sandrine, Weening Jan J.)
  • Dessing Mark C., van der Sluijs Koenraad F., Florquin Sandrine, Akira Shizuo, van der Poll Tom Toll-like receptor 2 does not contribute to host response during postinfluenza pneumococcal pneumonia American journal of respiratory cell and molecular biology 2007;36 (5):609-614 [PubMed]
  • Wiersinga W. Joost, Wieland Catharina W., Dessing Mark C., Chantratita Narisara, Cheng Allen C., Limmathurotsakul Direk, Chierakul Wirongrong, Leendertse Masja, Florquin Sandrine, de Vos Alex F., White Nicholas, Dondorp Arjen M., Day Nicholas P., Peacock Sharon J., van der Poll Tom Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis) PLoS medicine 2007;4 (7):e248-1280 [PubMed]
  • Grootscholten Cecile, Bajema Ingeborg M., Florquin Sandrine, Steenbergen Eric J., Peutz-Kootstra Carine J., Goldschmeding Roel, Bijl Marc, Hagen E. Christiaan, van Houwelingen Hans C., Derksen Ronald H. W. M., Berden Jo H. M. Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis Arthritis and rheumatism 2007;56 (3):924-937 [PubMed]

2006

  • Wieland Catharina W., Kerver Marjolein E., Florquin Sandrine, Nolte Martijn A., Borst Jannie, van Lier Rene, van Oers Marinus H. J., van der Poll Tom CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome International immunology 2006;18 (11):1531-1539 [PubMed]
  • Rouschop Kasper M. A., Claessen Nike, Pals Steven T., Weening Jan J., Florquin Sandrine CD44 disruption prevents degeneration of the capillary network in obstructive nephropathy via reduction of TGF-beta1-induced apoptosis Journal of the American Society of Nephrology 2006;17 (3):746-753 [PubMed]
  • Rouschop K. M. A. CD44 in renal disease: friend or foe? 2006. 171p. ISBN 9789052910956. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Weening J. J., Pals S. T.; Co-supervisor: Florquin S.)
  • Wieland Catharina W., Florquin Sandrine, Pater Jennie M., Weijer Sebastiaan, van der Poll Tom CD4+ cells play a limited role in murine lung infection with Mycobacterium kansasii American journal of respiratory cell and molecular biology 2006;34 (2):167-173 [PubMed]
  • Davin Jean-Claude, Olie Karolien H., Verlaak René, Horuz Flore, Florquin Sandrine, Weening Jan J., Groothoff Jaap W., Strain Lisa, Goodship Timothy H. J. Complement factor H-associated atypical hemolytic uremic syndrome in monozygotic twins: concordant presentation, discordant response to treatment American journal of kidney diseases 2006;47 (2):e27-e30 [PubMed]
  • de Waard Vivian, Hansen Hjalmar R., Spronk Henri H. M., Timmerman Janneke J., Pannekoek Hans, Florquin Sandrine, Reitsma Pieter H., ten Cate Hugo Differential expression of tissue factor mRNA and protein expression in murine sepsis. The role of the granulocyte revisited Thrombosis and haemostasis 2006;95 (2):348-353 [PubMed]
  • Knapp Sylvia, Wieland Catharina W., Florquin Sandrine, Pantophlet Ralph, Dijkshoorn Lenie, Tshimbalanga Ntambua, Akira Shizuo, van der Poll Tom Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia American journal of respiratory and critical care medicine 2006;173 (1):122-129 [PubMed]
  • Keller Tymen T., van der Sluijs Koen F., de Kruif Martijn D., Gerdes Victor E. A., Meijers Joost C. M., Florquin Sandrine, van der Poll Tom, van Gorp Eric C. M., Brandjes Dees P. M., Büller Harry R., Levi Marcel Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1 Circulation research 2006;99 (11):1261-1269 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Pater Jennie M., Lijnen H. Roger, Carmeliet Peter, van 't Veer Cornelis, van der Poll Tom Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice Journal of immunology (Baltimore, Md. 2006;177 (2):1189-1196 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Xiao Yanling, Arens Ramon, Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Jansen Henk M., Lutter René, van der Poll Tom IL-12 deficiency transiently improves viral clearance during the late phase of respiratory tract infection with influenza A virus in mice Antiviral research 2006;70 (2):75-84 [PubMed]
  • van der Sluijs Koenraad F., Nijhuis Monique, Levels Johannes H. M., Florquin Sandrine, Mellor Andrew L., Jansen Henk M., van der Poll Tom, Lutter René Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia Journal of infectious diseases 2006;193 (2):214-222 [PubMed]
  • Maris Nico A., Florquin Sandrine, van't Veer Cornelis, de Vos Alex F., Buurman Wim, Jansen Henk M., van der Poll Tom Inhalation of beta 2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract Respiratory research 2006;7:57 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, Pater Jennie M., Weijer Sebastiaan, van der Poll Tom Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract Microbes and infection / Institut Pasteur 2006;8 (9-10):2409-2413 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Shimizu Takao, Ishii Satoshi, Jansen Henk M., Lutter René, van der Poll Tom Involvement of the platelet-activating factor receptor in host defense against Streptococcus pneumoniae during postinfluenza pneumonia American journal of physiology. Lung cellular and molecular physiology 2006;290 (1):L194-L199 [PubMed]
  • Wieland Catharina W., Stegenga Michiel E., Florquin Sandrine, Fantuzzi Giamila, van der Poll Tom Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice Shock (Augusta, Ga.) 2006;25 (4):414-419 [PubMed]
  • Rijneveld Anita W., Weijer Sebastiaan, Bresser Paul, Florquin Sandrine, Vlasuk George P., Rote William E., Spek C. Arnold, Reitsma Pieter H., van der Zee Jaring S., Levi Marcel, van der Poll Tom Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia Critical care medicine 2006;34 (6):1725-1730 [PubMed]
  • Vedder A. C., Strijland A., van den Bergh Weerman M. A., Florquin S., Aerts J. M. F. G., Hollak C. E. M. Manifestations of Fabry disease in placental tissue Journal of inherited metabolic disease 2006;29 (1):106-111 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Lijnen H. Roger, van't Veer Cornelis, van der Poll Tom Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis Journal of immunology (Baltimore, Md. 2006;176 (6):3735-3741 [PubMed]
  • Leemans Jaklien C., Wieland Catharina W., Florquin Sandrine, van der Poll Tom, Vervoordeldonk Margriet J. B. M. Mice overexpressing p40 in lungs have reduced leucocyte influx and slightly impaired resistance during tuberculosis Immunology 2006;117 (3):409-418 [PubMed]
  • Roos-van Groningen Marian C., Scholten Eduard M., Lelieveld Patrick M., Rowshani Ajda T., Baelde Hans J., Bajema Ingeborg M., Florquin Sandrine, Bemelman Frederike J., de Heer Emile, de Fijter Johan W., Bruijn Jan A., Eikmans Michael Molecular comparison of calcineurin inhibitor-induced fibrogenic responses in protocol renal transplant biopsies Journal of the American Society of Nephrology 2006;17 (3):881-888 [PubMed]
  • Dessing Mark C., de Vos Alex F., Florquin Sandrine, van der Poll Tom Monocyte chemoattractant protein 1 does not contribute to protective immunity against pneumococcal pneumonia Infection and immunity 2006;74 (12):7021-7023 [PubMed]
  • Rowshani Ajda T., Scholten Eduard M., Bemelman Frederike, Eikmans Michael, Idu Mirza, Roos-van Groningen Marian C., van Groningen Marian C. R., Surachno Janto S., Mallat Marko J. K., Paul Leendert C., de Fijter Johan W., Bajema Ingeborg M., ten Berge Ineke, Florquin Sandrine No difference in degree of interstitial Sirius red-stained area in serial biopsies from area under concentration-over-time curves-guided cyclosporine versus tacrolimus-treated renal transplant recipients at one year Journal of the American Society of Nephrology 2006;17 (1):305-312 [PubMed]
  • van Veen Suzanne Q., Levi Marcel, van Vliet Arlène K., Florquin Sandrine, van Gulik Thomas M., Boermeester Marja A. Peritoneal lavage with activated protein C alters compartmentalized coagulation and fibrinolysis and improves survival in polymicrobial peritonitis Critical care medicine 2006;34 (11):2799-2805 [PubMed]
  • Knapp Sylvia, Florquin Sandrine, Golenbock Douglas T., van der Poll Tom Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo Journal of immunology (Baltimore, Md. 2006;176 (5):3189-3195 [PubMed]
  • Rouschop K. M. A., Roelofs J. J. T. H., Sylva M., Rowshani A. T., ten Berge I. J. M., Weening J. J., Florquin S. Renal expression of CD44 correlates with acute renal allograft rejection Kidney international 2006;70 (6):1127-1134 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Knapp Sylvia, de Vos Alex F., Florquin Sandrine, van der Poll Tom The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii Pneumonia Journal of infectious diseases 2006;193 (2):187-195 [PubMed]
  • Roelofs J. J. T. H., Rouschop K. M. A., Teske G. J. D., Claessen N., Weening J. J., van der Poll T., Florquin S. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis Kidney international 2006;70 (11):1942-1947 [PubMed]
  • van Westerloo David J., Giebelen Ilona A., Florquin Sandrine, Bruno Marco J., Larosa Gregory J., Ulloa Luis, Tracey Kevin J., van der Poll T. The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice Gastroenterology 2006;130 (6):1822-1830 [PubMed]
  • Roelofs Joris J. T. H., Rouschop Kasper M. A., Leemans Jaklien C., Claessen Nike, de Boer Anita M., Frederiks Wilma M., Lijnen H. Roger, Weening Jan J., Florquin Sandrine Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury Journal of the American Society of Nephrology 2006;17 (1):131-140 [PubMed]
  • Scholten Eduard M., Rowshani Ajda T., Cremers Serge, Bemelman Frederike J., Eikmans Michael, van Kan Erik, Mallat Marko J., Florquin Sandrine, Surachno Janto, ten Berge Ineke J., Bajema Ingeborg M., de Fijter Johan W. Untreated rejection in 6-month protocol biopsies is not associated with fibrosis in serial biopsies or with loss of graft function Journal of the American Society of Nephrology 2006;17 (9):2622-2632 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, van der Poll Tom Urokinase-type plasminogen activator receptor plays a role in neutrophil migration during lipopolysaccharide-induced peritoneal inflammation but not during Escherichia coli-induced peritonitis Journal of infectious diseases 2006;193 (4):522-530 [PubMed]
  • Rouschop Kasper M. A., Sylva Marc, Teske Gwendoline J. D., Hoedemaeker Inge, Pals Steven T., Weening Jan J., van der Poll Tom, Florquin Sandrine Urothelial CD44 facilitates Escherichia coli infection of the murine urinary tract Journal of immunology (Baltimore, Md. 2006;177 (10):7225-7232 [PubMed]

2005

  • Renckens Rosemarijn, Roelofs Joris J. T. H., ter Horst Simone A. J., van 't Veer Cornelis, Havik Stefan R., Florquin Sandrine, Wagenaar Gerry T. M., Meijers Joost C. M., van der Poll Tom Absence of thrombin-activatable fibrinolysis inhibitor protects against sepsis-induced liver injury in mice Journal of immunology (Baltimore, Md. 2005;175 (10):6764-6771 [PubMed]
  • van Westerloo David J., Knapp Sylvia, van't Veer Cornelis, Buurman Wim A., de Vos Alex F., Florquin Sandrine, van der Poll Tom Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia Critical care medicine 2005;33 (8):1770-1778 [PubMed]
  • Weijer Sebastiaan, Wieland Catharina W., Florquin Sandrine, van der Poll Tom A thrombomodulin mutation that impairs activated protein C generation results in uncontrolled lung inflammation during murine tuberculosis Blood 2005;106 (8):2761-2768 [PubMed]
  • Rijneveld Anita W., de Vos Alex F., Florquin Sandrine, Verbeek J. Sjef, van der Poll Tom CD11b limits bacterial outgrowth and dissemination during murine pneumococcal pneumonia Journal of infectious diseases 2005;191 (10):1755-1760 [PubMed]
  • Weijer Sebastiaan, Florquin Sandrine, van der Poll Tom Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis Shock (Augusta, Ga.) 2005;23 (1):54-58 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Arens Ramon, Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Kwakkel Joan, Akira Shizuo, Jansen Henk M., Lutter René, van der Polls Tom Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus Immunology 2005;114 (1):112-120 [PubMed]
  • Stokman Geurt, Leemans Jaklien C., Claessen Nike, Weening Jan J., Florquin Sandrine Hematopoietic stem cell mobilization therapy accelerates recovery of renal function independent of stem cell contribution Journal of the American Society of Nephrology 2005;16 (6):1684-1692 [PubMed]
  • Branger Judith, Leemans Jaklien C., Florquin Sandrine, Speelman Peter, Golenbock Douglas T., van der Poll Tom Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection Clinical immunology (Orlando, Fla.) 2005;116 (2):174-181 [PubMed]
  • Leemans Jaklien C., Thepen Theo, Weijer Sebastiaan, Florquin Sandrine, van Rooijen Nico, van de Winkel Jan G., van der Poll Tom Macrophages play a dual role during pulmonary tuberculosis in mice Journal of infectious diseases 2005;191 (1):65-74 [PubMed]
  • Olie Karolien H., Goodship Timothy H. J., Verlaak René, Florquin Sandrine, Groothoff Jaap W., Strain Lisa, Weening Jan J., Davin Jean-Claude Posttransplantation cytomegalovirus-induced recurrence of atypical hemolytic uremic syndrome associated with a factor H mutation: Successful treatment with intensive plasma exchanges and ganciclovir American journal of kidney diseases 2005;45 (1):E12-E15 [PubMed]
  • Rouschop Kasper M. A., Roelofs Joris J. T. H., Rowshani Ajda T., Leemans Jaklien C., van der Poll Tom, ten Berge Ineke J. M., Weening Jan J., Florquin Sandrine Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection Nephrology, dialysis, transplantation 2005;20 (10):2248-2254 [PubMed]
  • Rouschop Kasper M. A., Roelofs Joris J. T. H., Claessen Nike, da Costa Martins Paula, Zwaginga Jaap-Jan, Pals Steven T., Weening Jan J., Florquin Sandrine Protection against renal ischemia reperfusion injury by CD44 disruption Journal of the American Society of Nephrology 2005;16 (7):2034-2043 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, Chan Edward D., Leemans Jaklien C., Weijer Sebastiaan, Verbon Annelies, Fantuzzi Giamila, van der Poll Tom Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice International immunology 2005;17 (11):1399-1408 [PubMed]
  • Leemans Jaklien C., Stokman Geurt, Claessen Nike, Rouschop Kasper M., Teske Gwendoline J. D., Kirschning Carsten J., Akira Shizuo, van der Poll Tom, Weening Jan J., Florquin Sandrine Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney Journal of clinical investigation 2005;115 (10):2894-2903 [PubMed]
  • Sommeijer Dirkje W., Florquin Sandrine, Hoedemaker Inge, Timmerman Janneke J., Reitsma Pieter H., ten Cate Hugo Renal tissue factor expression is increased in streptozotocin-induced diabetic mice Nephron. Experimental nephrology 2005;101 (3):86-94 [PubMed]
  • Koppel Estella A., Wieland Catharina W., van den Berg Venice C. M., Litjens Manja, Florquin Sandrine, van Kooyk Yvette, van der Poll Tom, Geijtenbeek Teunis B. H. Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection European journal of immunology 2005;35 (10):2962-2969 [PubMed]
  • van Westerloo David J., Giebelen Ilona A. J., Florquin Sandrine, Daalhuisen Joost, Bruno Marco J., de Vos Alex F., Tracey Kevin J., van der Poll Tom The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis Journal of infectious diseases 2005;191 (12):2138-2148 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, Maris Nico A., Hoebe Kasper, Beutler Bruce, Takeda Kiyoshi, Akira Shizuo, van der Poll Tom The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable Haemophilus influenzae from the mouse lung Journal of immunology (Baltimore, Md. 2005;175 (9):6042-6049 [PubMed]
  • van Westerloo David J., Florquin Sandrine, de Boer Anita M., Daalhuisen Joost, de Vos Alex F., Bruno Marco J., van der Poll Tom Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice American journal of pathology 2005;166 (3):721-728 [PubMed]
  • Renckens R., Roelofs J. J. T. H., de Waard V., Florquin S., Lijnen H. R., Carmeliet P., van der Poll T. The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injury Journal of thrombosis and haemostasis 2005;3 (5):1018-1025 [PubMed]

2004

  • Knapp Sylvia, Hareng Lars, Rijneveld Anita W., Bresser Paul, van der Zee Jaring S., Florquin Sandrine, Hartung Thomas, van der Poll Tom Activation of neutrophils and inhibition of the proinflammatory cytokine response by endogenous granulocyte colony-stimulating factor in murine pneumococcal pneumonia Journal of infectious diseases 2004;189 (8):1506-1514 [PubMed]
  • van Westerloo David J., Schultz Marcus J., Bruno Marco J., de Vos Alex F., Florquin Sandrine, van der Poll Tom Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis Critical care medicine 2004;32 (10):1997-2001 [PubMed]
  • Olie Karolien H., Florquin Sandrine, Groothoff Jaap W., Verlaak René, Strain Lisa, Goodship Timothy H. J., Weening Jan J., Davin Jean-Claude Atypical relapse of hemolytic uremic syndrome after transplantation Pediatric nephrology (Berlin, Germany) 2004;19 (10):1173-1176 [PubMed]
  • Schoenmakers Saskia H. H. F., Groot Angelique P., Florquin Sandrine, Reitsma Pieter H., Spek C. Arnold Blood cell-derived tissue factor influences host response during murine endotoxemia Blood cells, molecules & diseases 2004;32 (2):325-333 [PubMed]
  • Rouschop Kasper M. A., Sewnath Miguel E., Claessen Nike, Roelofs Joris J. T. H., Hoedemaeker Inge, van der Neut Ronald, Aten Jan, Pals Steven T., Weening Jan J., Florquin Sandrine CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy Journal of the American Society of Nephrology 2004;15 (3):674-686 [PubMed]
  • Buonocore S., Flamand V., Claessen N., Heeringa P., Goldman M., Florquin S. Dendritic cells overexpressing Fas-ligand induce pulmonary vasculitis in mice Clinical and experimental immunology 2004;137 (1):74-80 [PubMed]
  • Rowshani Ajda T., Florquin Sandrine, Bemelman Frederike, Kummer J. Alain, Hack C. Erik, ten Berge Ineke J. M. Hyperexpression of the granzyme B inhibitor PI-9 in human renal allografts: A potential mechanism for stable renal function in patients with subclinical rejection Kidney international 2004;66 (4):1417-1422 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Nijhuis Monique, Schuurman Rob, Pater Jennie M., Florquin Sandrine, Goldman Michel, Jansen Henk M., Lutter René, van der Poll Tom IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection Journal of immunology (Baltimore, Md. 2004;172 (12):7603-7609 [PubMed]
  • Rijneveld Anita W., Weijer Sebastiaan, Florquin Sandrine, Speelman Peter, Shimizu Takao, Ishii Satosh, van der Poll Tom Improved host defense against pneumococcal pneumonia in platelet-activating factor receptor-deficient mice Journal of infectious diseases 2004;189 (4):711-716 [PubMed]
  • Weijer Sebastian, Schoenmakers Saskia H. H. F., Florquin Sandrine, Levi Marcel, Vlasuk George P., Rote William E., Reitsma Pieter H., Spek C. Arnold, van der Poll Tom Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice Journal of infectious diseases 2004;189 (12):2308-2317 [PubMed]
  • Branger Judith, Florquin Sandrine, Knapp Sylvia, Leemans Jaklien C., Pater Jennie M., Speelman Peter, Golenbock Douglas T., van der Poll Tom LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia International immunology 2004;16 (11):1605-1611 [PubMed]
  • Florquin S. Membranoproliferatieve glomerulonefritisin: J. A. Bruijn, editors. Praktische nefropathologie. Leiden: LUMC; 2004. p. 65-78, ISBN 9789067675505
  • Wieland Catharina W., Knapp Sylvia, Florquin Sandrine, de Vos Alex F., Takeda Kiyoshi, Akira Shizuo, Golenbock Douglas T., Verbon Annelies, van der Poll Tom Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2 American journal of respiratory and critical care medicine 2004;170 (12):1367-1374 [PubMed]
  • Branger Judith, Wieland Catharina W., Florquin Sandrine, Maris Nico A., Pater Jennie M., Speelman Peter, Shimizu Takao, Ishii Satoshi, van der Poll Tom Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable Haemophilus influenzae from their respiratory tract Shock (Augusta, Ga.) 2004;22 (6):543-547 [PubMed]
  • van den Berg José G., van den Bergh Weerman Marius A., Assmann Karel J. M., Weening Jan J., Florquin Sandrine Podocyte foot process effacement is not correlated with the level of proteinuria in human glomerulopathies Kidney international 2004;66 (5):1901-1906 [PubMed]
  • Branger Judith, Knapp Sylvia, Weijer Sebastiaan, Leemans Jaklien C., Pater Jennie M., Speelman Peter, Florquin Sandrine, van der Poll Tom Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice Infection and immunity 2004;72 (2):788-794 [PubMed]
  • Maris Nico A., van der Sluijs Koenraad F., Florquin Sandrine, de Vos Alex F., Pater Jennie M., Jansen Henk M., van der Poll Tom Salmeterol, a beta(2)-receptor agonist, attenuates lipopolysaccharide-induced lung inflammation in mice American journal of physiology. Lung cellular and molecular physiology 2004;286 (6):L1122-L1128 [PubMed]
  • Leemans Jaklien C., te Velde Anje A., Florquin Sandrine, Bennink Roelof J., de Bruin Kora, van Lier René A. W., van der Poll Tom, Hamann Jörg The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense Journal of immunology (Baltimore, Md. 2004;172 (2):1125-1131 [PubMed]
  • Rijneveld Anita W., Weijer Sebastiaan, Florquin Sandrine, Esmon Charles T., Meijers Joost C. M., Speelman Peter, Reitsma Pieter H., ten Cate Hugo, van der Poll Tom Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide Blood 2004;103 (5):1702-1709 [PubMed]
  • Knapp Sylvia, Wieland Catharina W., van 't Veer Cornelis, Takeuchi Osamu, Akira Shizuo, Florquin Sandrine, van der Poll Tom Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense Journal of immunology (Baltimore, Md. 2004;172 (5):3132-3138 [PubMed]
  • Branger Judith, Leemans Jaklien C., Florquin Sandrine, Weijer Sebastiaan, Speelman Peter, van der Poll Tom Toll-like receptor 4 plays a protective role in pulmonary tuberculosis in mice International immunology 2004;16 (3):509-516 [PubMed]
  • Florquin S. Tubulo-interstitiële nefritisin: J. A. Bruijn, editors. Praktische nefropathologie. Leiden: LUMC; 2004. p. 163-178, ISBN 9789067675505

2003

  • Levi Marcel, Dörffler-Melly Janine, Reitsma Pieter, Buller Harry, Florquin Sandrine, van der Poll Tom, Carmeliet Peter Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice Blood 2003;101 (12):4823-4827 [PubMed]
  • Knapp Sylvia, Leemans Jaklien C., Florquin Sandrine, Branger Judith, Maris Nico A., Pater Jennie, van Rooijen Nico, van der Poll Tom Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia American journal of respiratory and critical care medicine 2003;167 (2):171-179 [PubMed]
  • Rijneveld Anita W., Florquin Sandrine, Hartung Thomas, Speelman Peter, van der Poll Tom Anti-tumor necrosis factor antibody impairs the therapeutic effect of ceftriaxone in murine pneumococcal pneumonia Journal of infectious diseases 2003;188 (2):282-285 [PubMed]
  • Leemans Jaklien C., Florquin Sandrine, Heikens Mirjam, Pals Steven T., van der Neut Ronald, van der Poll Tom CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis Journal of clinical investigation 2003;111 (5):681-689 [PubMed]
  • Zwijnenburg Petra J. G., Polfliet Machteld M. J., Florquin Sandrine, van den Berg Timo K., Dijkstra Christine D., van Deventer Sander J. H., Roord John J., van der Poll Tom, van Furth A. Marceline CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats Immunology letters 2003;85 (1):1-4 [PubMed]
  • Roelofs Joris J. T. H., Rowshani Ajda T., van den Berg José G., Claessen Nike, Aten Jan, ten Berge Ineke J. M., Weening Jan J., Florquin Sandrine Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection Kidney international 2003;64 (5):1845-1853 [PubMed]
  • Dörffler-Melly Janine, de Kruif Martijn, Schwarte Lothar A., Franco Rendrik F., Florquin Sandrine, Spek C. Arnold, Ince Can, Reitsma Pieter H., ten Cate Hugo Functional thrombomodulin deficiency causes enhanced thrombus growth in a murine model of carotid artery thrombosis Basic research in cardiology 2003;98 (6):347-352 [PubMed]
  • Weijer Sebastiaan, Leemans Jaklien C., Florquin Sandrine, Shimizu Takao, Ishii Satoshi, van der Poll Tom Host response of platelet-activating factor receptor-deficient mice during pulmonary tuberculosis Immunology 2003;109 (4):552-556 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Roord John J., van Furth A. Marceline IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis Journal of immunology (Baltimore, Md. 2003;170 (9):4724-4730 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Roord John J., van Furth A. Marceline Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis Infection and immunity 2003;71 (4):2276-2279 [PubMed]
  • Weijer Sebastiaan, Sewnath Miguel E., de Vos Alex F., Florquin Sandrine, van der Sluis Koen, Gouma Dirk J., Takeda Kiyoshi, Akira Shizuo, van der Poll Tom Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis Infection and immunity 2003;71 (10):5488-5497 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Akira Shizuo, Takeda Kiyoshi, Roord John J., van Furth A. Marceline Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis Journal of neuroimmunology 2003;138 (1-2):31-37 [PubMed]
  • Schultz Marc J., Knapp Sylvia, Florquin Sandrine, Pater Jennie, Takeda Kiyoshi, Akira Shizuo, van der Poll Tom Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa Infection and immunity 2003;71 (4):1630-1634 [PubMed]
  • Rijneveld Anita W., Florquin Sandrine, Speelman Peter, Edwards Carl K., Dinarello Charles A., van der Poll Tom Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia European cytokine network 2003;14 (4):242-245 [PubMed]
  • Knapp Sylvia, de Vos Alex F., Florquin Sandrine, Golenbock Douglas T., van der Poll Tom Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice Infection and immunity 2003;71 (12):6747-6753 [PubMed]
  • Leemans Jaklien C., Heikens Mirjam, van Kessel Kok P. M., Florquin Sandrine, van der Poll Tom Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice Clinical and diagnostic laboratory immunology 2003;10 (5):950-953 [PubMed]
  • Rijneveld Anita W., Florquin Sandrine, Bresser Paul, Levi Marcel, de Waard Vivian, Lijnen Roger, van der Zee Jaring S., Speelman Peter, Carmeliet Peter, van der Poll Tom Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia Blood 2003;102 (3):934-939 [PubMed]
  • Florquin Sandrine, Rouschop Kasper M. A. Reciprocal functions of hepatocyte growth factor and transforming growth factor-beta1 in the progression of renal diseases: a role for CD44? Kidney international 2003;64 (Suppl. 86):S15-S20 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine, Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Jansen Henk M., Lutter René, van der Poll Tom Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus Immunology letters 2003;89 (2-3):201-206 [PubMed]
  • Meijer R. T., Surachno S., Yong S. L., Bemelman F. J., Florquin S., ten Berge I. J. M., Schellekens P. T. A. Treatment of acute kidney allograft rejection with a non-mitogenic CD3 antibody Clinical and experimental immunology 2003;133 (3):485-492 [PubMed]

2002

  • Florquin Sandrine, Nunziata Raffaele, Claessen Nike, van den Berg Frank M., Pals Steven T., Weening Jan J. CD44 expression in IgA nephropathy American journal of kidney diseases 2002;39 (2):407-414 [PubMed]
  • Juffermans Nicole P., Leemans Jaklien C., Florquin Sandrine, Verbon Annelies, Kolk Arend H., Speelman Peter, van Deventer Sander J. H., van der Poll Tom CpG oligodeoxynucleotides enhance host defense during murine tuberculosis Infection and immunity 2002;70 (1):147-152 [PubMed]
  • Leemans Jaklien C., Vervoordeldonk Margriet J. B. M., Florquin Sandrine, van Kessel Kok P., van der Poll Tom Differential role of interleukin-6 in lung inflammation induced by lipoteichoic acid and peptidoglycan from Staphylococcus aureus American journal of respiratory and critical care medicine 2002;165 (10):1445-1450 [PubMed]
  • Lauw Fanny N., Branger Judith, Florquin Sandrine, Speelman Peter, van Deventer Sander J. H., Akira Shizuo, van der Poll Tom IL-18 improves the early antimicrobial host response to pneumococcal pneumonia Journal of immunology (Baltimore, Md. 2002;168 (1):372-378 [PubMed]
  • Verbon A., Leemans J. C., Weijer S., Florquin S., van der Poll T. Mice lacking the multidrug resistance protein 1 have a transiently impaired immune response during tuberculosis Clinical and experimental immunology 2002;130 (1):32-36 [PubMed]
  • Schultz Marc J., Rijneveld Anita W., Florquin Sandrine, Edwards Carl K., Dinarello Charles A., van der Poll Tom Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia American journal of physiology. Lung cellular and molecular physiology 2002;282 (2):L285-L290 [PubMed]
  • Rijneveld Anita W., van den Dobbelsteen Germie P., Florquin Sandrine, Standiford Theodore J., Speelman Peter, van Alphen Loek, van der Poll Tom Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice Journal of infectious diseases 2002;185 (1):123-126 [PubMed]
  • Rijneveld Anita W., Lauw Fanny N., Schultz Marc J., Florquin Sandrine, te Velde Anje A., Speelman Peter, van Deventer Sander J. H., van der Poll Tom The role of interferon-gamma in murine pneumococcal pneumonia Journal of infectious diseases 2002;185 (1):91-97 [PubMed]
  • Lettinga Kamilla D., Florquin Sandrine, Speelman Peter, van Ketel Ruud, van der Poll Tom, Verbon Annelies Toll-like receptor 4 is not involved in host defense against pulmonary Legionella pneumophila infection in a mouse model Journal of infectious diseases 2002;186 (4):570-573 [PubMed]
  • Rijneveld Anita W., Levi Marcel, Florquin Sandrine, Speelman Peter, Carmeliet Peter, van der Poll Tom Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia Journal of immunology (Baltimore, Md. 2002;168 (7):3507-3511 [PubMed]

2001

  • Noël C., Florquin S., Goldman M., Braun M. Y. Chronic exposure to superantigen induces regulatory CD4(+) T cells with IL-10-mediated suppressive activity International immunology 2001;13 (4):431-439 [PubMed]
  • Olszyna D. P., Florquin S., Sewnath M., Branger J., Speelman P., van Deventer S. J., Strieter R. M., van der Poll T. CXC chemokine receptor 2 contributes to host defense in murine urinary tract infection Journal of infectious diseases 2001;184 (3):301-307 [PubMed]
  • Leemans J. C., Juffermans N. P., Florquin S., van Rooijen N., Vervoordeldonk M. J., Verbon A., van Deventer S. J., van der Poll T. Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice Journal of immunology (Baltimore, Md. 2001;166 (7):4604-4611 [PubMed]
  • Langermans J. A., Andersen P., van Soolingen D., Vervenne R. A., Frost P. A., van der Laan T., van Pinxteren L. A., van den Hombergh J., Kroon S., Peekel I., Florquin S., Thomas A. W. Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research Proceedings of the National Academy of Sciences of the United States of America 2001;98 (20):11497-11502 [PubMed]
  • Zwijnenburg P. J., van der Poll T., Florquin S., van Deventer S. J., Roord J. J., van Furth A. M. Experimental pneumococcal meningitis in mice: a model of intranasal infection Journal of infectious diseases 2001;183 (7):1143-1146 [PubMed]
  • Schultz M. J., Rijneveld A. W., Florquin S., Speelman P., van Deventer S. J., van der Poll T. Impairment of host defence by exotoxin A in Pseudomonas aeruginosa pneumonia in mice Journal of medical microbiology 2001;50 (9):822-827 [PubMed]
  • Florquin S., van den Berg J. G., Olszyna D. P., Claessen N., Opal S. M., Weening J. J., van der Poll T. Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia Kidney international 2001;59 (6):2054-2061 [PubMed]
  • Lauw F. N., Florquin S., Speelman P., van Deventer S. J., van der Poll T. Role of endogenous interleukin-12 in immune response to staphylococcal enterotoxin B in mice Infection and immunity 2001;69 (9):5949-5952 [PubMed]
  • Florquin S., Roos A., Groothoff J. W., Claessen N., van Gijlswijk-Janssen D. J., Aten J., Davin J. C., Weening J. J. Severe non-proliferative lupus nephritis with predominant sub-endothelial IgA deposits Nephrology, dialysis, transplantation 2001;16 (7):1479-1482 [PubMed]
  • Rijneveld A. W., Florquin S., Branger J., Speelman P., van Deventer S. J., van der Poll T. TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia Journal of immunology (Baltimore, Md. 2001;167 (9):5240-5246 [PubMed]

2000

  • Glomerulopathy associated with parasitic infections Clinical microbiology reviews 2000;13 (1):55-66, table of contents [PubMed]
  • Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis Journal of infectious diseases 2000;182 (3):902-908 [PubMed]

1999

  • Interactions between cytochrome P-450 activities and ozone-induced modulatory effects on endothelial permeability in rabbit lungs: influence of gender Inhalation toxicology 1999;11 (11):999-1014 [PubMed]
  • T cell subsets in experimental lupus nephritis: modulation by bacterial superantigen Nephrology, dialysis, transplantation 1999;14 (Suppl. 1):14-16 [PubMed]

1997

  • Superantigens: a tool to gain new insight into cellular immunity Research in immunology 1997;148 (6):373-386 [PubMed]

1996

  • Immunoregulatory mechanisms of T-cell-dependent shock induced by a bacterial superantigen in mice Infection and immunity 1996;64 (9):3443-3445 [PubMed]
  • Persistent production of TH2-type cytokines and polyclonal B cell activation after chronic administration of staphylococcal enterotoxin B in mice Journal of autoimmunity 1996;9 (5):609-615 [PubMed]

1995

  • T cells made deficient in interleukin-2 production by exposure to staphylococcal enterotoxin B in vivo are primed for interferon-gamma and interleukin-10 secretion European journal of immunology 1995;25 (5):1148-1153 [PubMed]

1994

  • Effects of systemic administration of rIL-10 in an in vivo model of alloreactivity Transplantation 1994;58 (8):972-974 [PubMed]
  • IFN-gamma prevents Th2 cell-mediated pathology after neonatal injection of semiallogenic spleen cells in mice Journal of immunology (Baltimore, Md. 1994;153 (6):2361-2368 [PubMed]
  • Rôle de l'interleukine-10 dans la régulation des résponses immunes en pathologie infectieuse Revue medicale de Bruxelles 1994;15 (2):61-65 [PubMed]
  • Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice Journal of immunology (Baltimore, Md. 1994;153 (6):2618-2623 [PubMed]
  • T cell subsets in glomerular diseases Springer seminars in immunopathology 1994;16 (1):71-80 [PubMed]
  • The protective role of endogenously synthesized nitric oxide in staphylococcal enterotoxin B-induced shock in mice Journal of experimental medicine 1994;180 (3):1153-1158 [PubMed]

1993

  • Colony stimulating factor-1 in the induction of lupus nephritis Kidney international 1993;43 (5):1000-1009 [PubMed]

1992

  • Autoreactive kidney-infiltrating T-cell clones in murine lupus nephritis Kidney international 1992;42 (4):851-859 [PubMed]
  • Early recurrence of hemolytic uremic syndrome in a renal transplant recipient during prophylactic OKT3 therapy Transplantation 1992;53 (6):1378-1379 [PubMed]
  • Induction of thromboses within renal grafts by high-dose prophylactic OKT3 Lancet 1992;339 (8796):777-778 [PubMed]
  • Trichoderma viride infection in a liver transplant recipient Mycoses 1992;35 (11-12):301-303 [PubMed]

1991

  • Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: prevention by high doses of methylprednisolone Journal of immunology (Baltimore, Md. 1991;146 (4):1184-1191 [PubMed]
  • Néphrotoxicité des anticorps monoclonaux anti-CD3 Néphrologie 1991;12 (1):42-45 [PubMed]
  • Renal immunopathology in murine host-versus-graft disease Kidney international 1991;40 (5):852-861 [PubMed]

1990

  • Acute toxicity of anti-CD3 monoclonal antibody in mice: a model for OKT3 first dose reactions Transplantation proceedings 1990;22 (4):1920-1921 [PubMed]