Prof. T.K. van den Berg PhD publications

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Publications Prof. PhD T.K. van den Berg

Position
Assistant Professor
Main activities
Research
Specialisation
Immunotherapy
Focus of research

Our group at the Phagocyte Laboratory (Sanquin Research) of the Landsteiner Laboratory is interested in antibody immunotherapy against cancer. The major aim is to improve treatment of cancer patients with therapeutic antibodies in order to reduce the need for non-specific agents, such as chemotherapeutics. We have identified CD47-SIRPalpha interactions as an innate immune checkpoint during antibody therapy in cancer. Work is ongoing to explore the mechanisms of antibody-dependent cancer cell destruction by human innate immune cells and the ways in which this can be further improved. We are also interested in the role of innate immune cells in other diseases, including primary immunodeficiencies. In that context the Phagocyte Laboratory also provides a specialized diagnostic service for phagocyte functional and genetic defects.

Please also see our webpage of the laboratory of Blood Cell Research at Sanquin:

http://www.sanquin.nl/en/research/principal-investigators/pi-timo-vanden-berg/

Amsterdam UMC Research Institutes
AMC departments
All publications

2021

  • Bouti Panagiota, Zhao Xi Wen, Verkuijlen Paul J. J. H., Tool Anton T. J., van Houdt Michel, Köker Nezihe, Köker Mustafa Yavuz, Keskin Ozlem, Akbayram Sinan, van Bruggen Robin, Kuijpers Taco W., Matlung Hanke L., van den Berg Timo K. Kindlin3-dependent CD11b/CD18-integrin activation is required for potentiation of neutrophil cytotoxicity by CD47-SIRPa checkpoint disruption Cancer immunology research 2021;9 (2):147-155 [PubMed]
  • Aarts Cathelijn E. M., Downes Kate, Hoogendijk Arie J., Sprenkeler Evelien G. G., Gazendam Roel P., Favier Remi, Favier Marie, Tool Anton T. J., van Hamme John L., Kostadima Myrto A., Waller Kate, Zieger Barbara, van Bergen Maaike G. J. M., Langemeijer Saskia M. C., van der Reijden Bert A., Janssen Hans, van den Berg Timo K., van Bruggen Robin, Meijer Alexander B., Ouwehand Willem H., Kuijpers Taco W. Neutrophil specific granule and NETosis defects in gray platelet syndrome Blood advances 2021;5 (2):549-564 [PubMed]

2020

  • Scheenstra Maaike R., Martínez-Botía Patricia, Acebes-Huerta Andrea, Brouwer Rutger W. W., Caballero-Sánchez Noemí, Gillemans Nynke, de Bleser Pieter, Nota Benjamin, de Cuyper Iris M., Salunkhe Vishal, Woltman Andrea M., van de Laar Lianne, Rijkers Erikjan, Demmers Jeroen A. A., van IJcken Wilfred F. J., Philipsen Sjaak, van den Berg Timo K., Kuijpers Taco W., Gutiérrez Laura Comparison of the PU.1 transcriptional regulome and interactome in human and mouse inflammatory dendritic cells Journal of leukocyte biology 2020 [PubMed]
  • Treffers Louise W., ten Broeke Toine, Rösner Thies, Jansen J. H. Marco, van Houdt Michel, Kahle Steffen, Schornagel Karin, Verkuijlen Paul J. J. H., Prins Jan M., Franke Katka, Kuijpers Taco W., van den Berg Timo K., Valerius Thomas, Leusen Jeanette H. W., Matlung Hanke L. IgA-mediated killing of tumor cells by neutrophils is enhanced by CD47–SIRPA checkpoint inhibition Cancer immunology research 2020;8 (1):120-130 [PubMed]
  • Sprenkeler Evelien G. G., Henriet Stefanie S. V., Tool Anton T. J., Kreft Iris C., van der Bijl Ivo, Aarts Cathelijn E. M., van Houdt Michel, Verkuijlen Paul J. J. H., van Aerde Koen, Jaspers Gerald, van Heijst Arno, Koole Wouter, Gardeitchik Thatjana, Geissler Judy, de Boer Martin, Tol Simon, Bruggeman Christine W., van Alphen Floris P. J., Verhagen Han J. M. P., van den Akker Emile, Janssen Hans, van Bruggen Robin, van den Berg Timo K., Liem Kian D., Kuijpers Taco W. MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization Blood 2020;135 (24):2171-2181 [PubMed]
  • Franke Katka, Pillai Saravanan Y., Hoogenboezem Mark, Gijbels Marion J. J., Matlung Hanke L., Geissler Judy, Olsman Hugo, Pottgens Chantal, van Gorp Patrick J., Ozsvar-Kozma Maria, Saito Yasuyuki, Matozaki Takashi, Kuijpers Taco W., Hendriks Rudi W., Kraal Georg, Binder Christoph J., de Winther Menno P. J., van den Berg Timo K. SIRPα on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production Frontiers in immunology 2020;11 [PubMed]
  • Nagelkerke Sietse Q., Porcelijn Leendert, Geissler Judy, Tanck Michael W. T., Huiskes Elly, van Bruggen Robin, van den Berg Timo K., de Haas Masja, Kuijpers Taco W. The association and functional relevance of genetic variation in low-to-medium-affinity Fc-gamma receptors with clinical platelet transfusion refractoriness Journal of thrombosis and haemostasis 2020;18 (8):2047-2053 [PubMed]

2019

  • Salunkhe Vishal, de Cuyper Iris M., Papadopoulos Petros, van der Meer Pieter F., Daal Brunette B., Villa-Fajardo María, de Korte Dirk, van den Berg Timo K., Gutiérrez Laura A comprehensive proteomics study on platelet concentrates: Platelet proteome, storage time and Mirasol pathogen reduction technology Platelets 2019;30 (3):368-379 [PubMed]
  • Aarts Cathelijn E. M., Hiemstra Ida H., Béguin Eelke P., Hoogendijk Arjan J., Bouchmal Souhailla, van Houdt Michel, Tool Anton T. J., Mul Erik, Jansen Machiel H., Janssen Hans, van Alphen Floris P. J., de Boer Jan-Paul, Zuur Charlotte L., Meijer Alexander B., van den Berg Timo K., Kuijpers Taco W. Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair Blood advances 2019;3 (22):3562-3574 [PubMed]
  • Bruggeman Christina W. Expression and function of Fc-gamma receptors: Binding of immunoglobulin G and its glycoforms 2019. 184p. ISBN 9789463235228. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers Taco W.; Co-supervisor: van den Berg Timo K.)
  • Nagelkerke Sietse Q., Tacke Carline E., Breunis Willemijn B., Tanck Michael W. T., Geissler Judy, Png Eileen, Hoang Long T., van der Heijden Joris, Naim Ahmad N. M., Yeung Rae S. M., Levin Michael L., Wright Victoria J., Burgner David P., Ponsonby Anne-Louise, Ellis Justine A., Cimaz Rolando, Shimizu Chisato, Burns Jane C., Fijnvandraat Karin, van der Schoot C. Ellen, van den Berg Timo K., de Boer Martin, Davila Sonia, Hibberd Martin L., Kuijpers Taco W., Dahdah Nagib, Kone-Paut Isabelle Extensive Ethnic Variation and Linkage Disequilibrium at the FCGR2/3 Locus: Different Genetic Associations Revealed in Kawasaki Disease Frontiers in immunology 2019;10:185 [PubMed]
  • Treffers Louise W., van Houdt Michel, Bruggeman Christine W., Heineke Marieke H., Zhao Xi Wen, van der Heijden Joris, Nagelkerke Sietse Q., Verkuijlen Paul J. J. H., Geissler Judy, Lissenberg-Thunnissen Suzanne, Valerius Thomas, Peipp Matthias, Franke Katka, van Bruggen Robin, Kuijpers Taco W., van Egmond Marjolein, Vidarsson Gestur, Matlung Hanke L., van den Berg Timo K. FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer Cells by Human Neutrophils Frontiers in immunology 2019;9 [PubMed]
  • Logtenberg Meike E. W., Jansen J. H. Marco, Raaben Matthijs, Toebes Mireille, Franke Katka, Brandsma Arianne M., Matlung Hanke L., Fauster Astrid, Gomez-Eerland Raquel, Bakker Noor A. M., van der Schot Simone, Marijt Koen A., Verdoes Martijn, Haanen John B. A. G., van den Berg Joost H., Neefjes Jacques, van den Berg Timo K., Brummelkamp Thijn R., Leusen Jeanette H. W., Scheeren Ferenc A., Schumacher Ton N. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy Nature medicine 2019;25 (4):612-619 [PubMed]
  • Meinderts Sanne M, Gerritsma Jorn J, Sins Joep W R, de Boer Martin, van Leeuwen Karin, Biemond Bart J, Rijneveld Anita W, Kerkhoffs Jean-Louis H, Habibi Anoosha, van Bruggen Robin, Kuijpers Taco W, van der Schoot Ellen, Pirenne France, Fijnvandraat Karin, Tanck Michael W, van den Berg Timo K Identification of genetic biomarkers for alloimmunization in sickle cell disease British journal of haematology 2019;186 (6):887-899 [PubMed]
  • Rösner Thies, Kahle Steffen, Montenegro Francesca, Matlung Hanke L, Jansen J H Marco, Evers Mitchell, Beurskens Frank, Leusen Jeanette H W, van den Berg Timo K, Valerius Thomas Immune Effector Functions of Human IgG2 Antibodies against EGFR Molecular cancer therapeutics 2019;18 (1):75-88 [PubMed]
  • van den Berg Timo K, Valerius Thomas Myeloid immune-checkpoint inhibition enters the clinical stage Nature reviews. Clinical oncology 2019;16:275-276 [PubMed]
  • Meinderts Sanne M., Baker Gabriella, van Wijk Stan, Beuger Boukje M., Geissler Judy, Jansen Machiel H., Saris Anno, Brinke Anja Ten, Kuijpers Taco W., van den Berg Timo K., van Bruggen Robin Neutrophils acquire antigen-presenting cell features after phagocytosis of IgG-opsonized erythrocytes Blood advances 2019;3 (11):1761-1773 [PubMed]
  • Aarts Cathelijn E. M., Hiemstra Ida H., Tool Anton T. J., van den Berg T. K., Mul Erik, van Bruggen Robin, Kuijpers Taco W. Neutrophils as Suppressors of T Cell Proliferation: Does Age Matter? Frontiers in immunology 2019;10:2144 [PubMed]
  • Bruggeman Christine W., Houtzager Julia, Dierdorp Barbara, Kers Jesper, Pals Steven T., Lutter René, van Gulik Thomas, den Haan Joke M. M., van den Berg Timo K., van Bruggen Robin, Kuijpers Taco W. Tissue-specific expression of IgG receptors by human macrophages ex vivo PLoS ONE 2019;14 (10) [PubMed]

2018

  • de Boer Martin, Gavrieli Ronit, van Leeuwen Karin, Wolf Haike Reznik, Dushnitzki Maya, Bar-Yosef Yifaat, Bar-Ziv Anat, Behar Doron, Lipitz Shlomo, Miller Tal Elkan, Tool Anton T. J., Kuijpers Taco W., van den Berg Timo K., Wolach Baruch, Roos Dirk, Pras Elon A false-carrier state for the c.579G>A mutation in the NCF1 gene in Ashkenazi Jews Journal of medical genetics 2018;55 (3):166-172 [PubMed]
  • Grassi Luigi, Pourfarzad Farzin, Ullrich Sebastian, Merkel Angelika, Were Felipe, Carrillo-de-Santa-Pau Enrique, Yi Guoqiang, Hiemstra Ida H., Tool Anton T. J., Mul Erik, Perner Juliane, Janssen-Megens Eva, Berentsen Kim, Kerstens Hinri, Habibi Ehsan, Gut Marta, Yaspo Marie Laure, Linser Matthias, Lowy Ernesto, Datta Avik, Clarke Laura, Flicek Paul, Vingron Martin, Roos Dirk, van den Berg Timo K., Heath Simon, Rico Daniel, Frontini Mattia, Kostadima Myrto, Gut Ivo, Valencia Alfonso, Ouwehand Willem H., Stunnenberg Hendrik G., Martens Joost H. A., Kuijpers Taco W. Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils Cell reports 2018;24 (10):2784-2794 [PubMed]
  • Treffers Louise W., Zhao Xi Wen, van der Heijden Joris, Nagelkerke Sietse Q., van Rees Dieke J., Gonzalez Patricia, Geissler Judy, Verkuijlen Paul, van Houdt Michel, de Boer Martin, Kuijpers Taco W., van den Berg Timo K., Matlung Hanke L. Genetic variation of human neutrophil Fc gamma receptors and SIRP alpha in antibody-dependent cellular cytotoxicity towards cancer cells European journal of immunology 2018;48 (2):344-354 [PubMed]
  • Klei T. R. L., de Back D. Z., Asif P. J., Verkuijlen P. J. J. H., Veldthuis M., Ligthart P. C., Berghuis J., Clifford E., Beuger B. M., van den Berg T. K., van Zwieten R., El Nemer W., van Bruggen R. Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging Blood advances 2018;2 (1):14-24 [PubMed]
  • Bruggeman Christine W., Dekkers Gillian, Visser Remco, Goes Naneth W. M., van den Berg Timo K., Rispens Theo, Vidarsson Gestur, Kuijpers Taco W. IgG glyco-engineering to improve IVIg potency Frontiers in immunology 2018;9 (OCT) [PubMed]
  • van de Geer Annemarie, Nieto-Patlán Alejandro, Kuhns Douglas B., Tool Anton T. J., Arias Andrés A., Bouaziz Matthieu, de Boer Martin, Franco José Luis, Gazendam Roel P., van Hamme John L., van Houdt Michel, van Leeuwen Karin, Verkuijlen Paul J. H., van den Berg Timo K., Alzate Juan F., Arango-Franco Carlos A., Batura Vritika, Bernasconi Andrea R., Boardman Barbara, Booth Claire, Burns Siobhan O., Cabarcas Felipe, Bensussan Nadine Cerf, Charbit-Henrion Fabienne, Corveleyn Anniek, Deswarte Caroline, Azcoiti María Esnaola, Foell Dirk, Gallin John I., Garcés Carlos, Guedes Margarida, Hinze Claas H., Holland Steven M., Hughes Stephen M., Ibañez Patricio, Malech Harry L., Meyts Isabelle, Moncada-Velez Marcela, Moriya Kunihiko, Neves Esmeralda, Oleastro Matias, Perez Laura, Rattina Vimel, Oleaga-Quintas Carmen, Warner Neil, Muise Aleixo M., López Jeanet Serafín, Trindade Eunice, Vasconcelos Julia, Vermeire S. verine, Wittkowski Helmut, Worth Austen, Abel Laurent, Dinauer Mary C., Arkwright Peter D., Roos Dirk, Casanova Jean-Laurent, Kuijpers Taco W., Bustamante Jacinta Inherited p40phox deficiency differs from classic chronic granulomatous disease Journal of clinical investigation 2018;128 (9):3957-3975 [PubMed]
  • Matlung Hanke L., Babes Liane, Zhao Xi Wen, van Houdt Michel, Treffers Louise W., van Rees Dieke J., Franke Katka, Schornagel Karin, Verkuijlen Paul, Janssen Hans, Halonen Pasi, Lieftink Cor, Beijersbergen Roderick L., Leusen Jeanette H. W., Boelens Jaap J., Kuhnle Ingrid, van der Werff ten Bosch Jutte, Seeger Karl, Rutella Sergio, Pagliara Daria, Matozaki Takashi, Suzuki Eiji, Menke-van der Houven van Oordt Catharina Willemien, van Bruggen Robin, Roos Dirk, van Lier Rene A. W., Kuijpers Taco W., Kubes Paul, van den Berg Timo K. Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis Cell reports 2018;23 (13):3946-3959.e6 [PubMed]
  • Nagelkerke Sietse Q, Bruggeman Christine W, van den Berg Timo K, van Bruggen Robin, Kuijpers Taco W Red pulp macrophages in the human spleen are a distinct cell population with a unique expression of Fc-γ receptors Blood advances 2018;2 (8):941-953 [PubMed]

2017

  • Nagelkerke Sietse Q. A field guide to human Fc-gamma receptors: Genetics, cellular expression and interaction with immunoglobulins 2017. 305p. ISBN 9789462995703. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers T. W.; Co-supervisor: van den Berg T. K.)
  • van de Geer A., Gazendam R. P., Tool A. T. J., van Hamme J. L., de Korte D., van den Berg T. K., Zeerleder S. S., Kuijpers T. W. Characterization of buffy coat-derived granulocytes for clinical use: a comparison with granulocyte colony-stimulating factor/dexamethasone-pretreated donor-derived products Vox sanguinis 2017;112 (2):173-182 [PubMed]
  • Kuijpers Taco W., Tool Anton T. J., van der Bijl Ivo, de Boer Martin, van Houdt Michel, de Cuyper Iris M., Roos Dirk, van Alphen Floris, van Leeuwen Karin, Cambridge Emma L., Arends Mark J., Dougan Gordon, Clare Simon, Ramirez-Solis Ramiro, Pals Steven T., Adams David J., Meijer Alexander B., van den Berg Timo K. Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency Journal of allergy and clinical immunology 2017;140 (1):273-+ [PubMed]
  • Dekkers Gillian, Treffers Louise, Plomp Rosina, Bentlage Arthur E. H., de Boer Marcella, Koeleman Carolien A. M., Lissenberg-Thunnissen Suzanne N., Visser Remco, Brouwer Mieke, Mok Juk Yee, Matlung Hanke, van den Berg Timo K., van Esch Wim J. E., Kuijpers Taco W., Wouters Diana, Rispens Theo, Wuhrer Manfred, Vidarsson Gestur Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities Frontiers in immunology 2017;8:877 [PubMed]
  • Hiemstra Ida H., van Hamme John L., Janssen Machiel H., van den Berg Timo K., Kuijpers Taco W. Dexamethasone promotes granulocyte mobilization by prolonging the half-life of granulocyte-colony-stimulating factor in healthy donors for granulocyte transfusions Transfusion 2017;57 (3):674-684 [PubMed]
  • Bruggeman Christine W., Dekkers Gillian, Bentlage Arthur E. H., Treffers Louise W., Nagelkerke Sietse Q., Lissenberg-Thunnissen Suzanne, Koeleman Carolien A. M., Wuhrer Manfred, van den Berg Timo K., Rispens Theo, Vidarsson Gestur, Kuijpers Taco W. Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile Journal of immunology (Baltimore, Md. 2017;199 (1):204-211 [PubMed]
  • Klei Thomas R. L., Meinderts Sanne M., van den Berg Timo K., van Bruggen Robin From the Cradle to the Grave: The Role of Macrophages in erythropoiesis and erythrophagocytosis Frontiers in immunology 2017;8:73 [PubMed]
  • de Boer Martin, van Leeuwen Karin, Geissler Judy, van Alphen Floris, de Vries Esther, van der Kuip Martijn, Terheggen Suzanne W. J., Janssen Hans, van den Berg Timo K., Meijer Alexander B., Roos Dirk, Kuijpers Taco W. Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils Human mutation 2017;38 (10):1402-1411 [PubMed]
  • Meinderts Sanne M., Oldenborg Per-Arne, Beuger Boukje M., Klei Thomas R. L., Johansson Johanna, Kuijpers Taco W., Matozaki Takashi, Huisman Elise J., de Haas Masja, van den Berg Timo K., van Bruggen Robin Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells Blood advances 2017;1 (14):875-886 [PubMed]
  • van der Spek Anne H., Surovtseva Olga V., Aan Saskia, Tool Anton T. J., van de Geer Annemarie, Demir Korcan, van Gucht Anja L. M., van Trotsenburg A. S. Paul, van den Berg Timo K., Fliers Eric, Boelen Anita Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor alpha Endocrine connections 2017;6 (8):731-740 [PubMed]
  • Meinderts Sanne M., Sins Joep W. R., Fijnvandraat Karin, Nagelkerke Sietse Q., Geissler Judy, Tanck Michael W., Bruggeman Christine, Biemond Bart J., Rijneveld Anita W., Kerkhoffs Jean-Louis H., Pakdaman Sadaf, Habibi Anoosha, van Bruggen Robin, Kuijpers Taco W., Pirenne France, van den Berg Timo K. Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease Blood 2017;130 (19):2121-2130 [PubMed]
  • Matlung Hanke L., Szilagyi Katka, Barclay Neil A., van den Berg Timo K. The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer Immunological reviews 2017;276 (1):145-164 [PubMed]
  • Verbij Fabian C., Sorvillo Nicoletta, Kaijen Paul H. P., Hrdinova Johana, Peyron Ivan, Fijnheer Rob, ten Brinke Anja, Meijer Alexander B., van Alphen Floris P. J., van den Berg Timo K., Graversen Jonas J. H., Moestrup Soren K., Voorberg Jan The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages Blood advances 2017;1 (5):293-305 [PubMed]
  • Yipp Bryan G., Kim Jung Hwan, Lima Ronald, Zbytnuik Lori D., Petri Björn, Swanlund Nick, Ho May, Szeto Vivian G., Tak Tamar, Koenderman Leo, Pickkers Peter, Tool Anton T. J., Kuijpers Taco W., van den Berg Timo K., Looney Mark R., Krummel Matthew F., Kubes Paul The Lung is a Host Defense Niche for Immediate Neutrophil-Mediated Vascular Protection Science immunology 2017;2 (10) [PubMed]

2016

  • Scheenstra Maaike R., de Cuyper Iris M., Branco-Madeira Filipe, de Bleser Pieter, Kool Mirjam, Meinders Marjolein, Hoogenboezem Mark, Mul Erik, Wolkers Monika C., Salerno Fiamma, Nota Benjamin, Saeys Yvan, Klarenbeek Sjoerd, van Ijcken Wilfred F. J., Hammad Hamida, Philipsen Sjaak, van den Berg Timo K., Kuijpers Taco W., Lambrecht Bart N., Gutiérrez Laura GATA1-Deficient Dendritic Cells Display Impaired CCL21-Dependent Migration toward Lymph Nodes Due to Reduced Levels of Polysialic Acid Journal of immunology (Baltimore, Md. 2016;197 (11):4312-4324 [PubMed]
  • Gazendam Roel P., van de Geer Annemarie, Roos Dirk, van den Berg Timo K., Kuijpers Taco W. How neutrophils kill fungi Immunological reviews 2016;273 (1):299-311 [PubMed]
  • Gazendam Roel P., van Hamme John L., Tool Anton T. J., Hoogenboezem Mark, van den Berg J. Merlijn, Prins Jan M., Vitkov Ljubomir, van de Veerdonk Frank L., van den Berg Timo K., Roos Dirk, Kuijpers Taco W. Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects Journal of immunology (Baltimore, Md. 2016;196 (3):1272-1283 [PubMed]
  • Matlung Hanke L., Szilagyi Katka, Kuijpers Taco W., van Lier Rene A. W., van den Berg Timo K. Immune checkpoint blockade: Which switches to hit and how much? Immunology letters 2016;180:73-74 [PubMed]
  • van Rees Dieke J., Szilagyi Katka, Kuijpers Taco W., Matlung Hanke L., van den Berg Timo K. Immunoreceptors on neutrophils Seminars in immunology 2016;28 (2):94-108 [PubMed]
  • Gazendam Roel P., van de Geer Annemarie, van Hamme John L., Tool Anton T. J., van Rees Dieke J., Aarts Cathelijn E. M., van den Biggelaar Maartje, van Alphen Floris, Verkuijlen Paul, Meijer Alexander B., Janssen Hans, Roos Dirk, van den Berg Timo K., Kuijpers Taco W. Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components Haematologica 2016;101 (5):587-596 [PubMed]
  • Gazendam Roel P. Neutrophil microbial killing mechanisms: Lessons learned from primary immunodeficiencies 2016. 336p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers T. W.; Co-supervisors: van den Berg T. K., Roos D.)
  • Treffers Louise W., Hiemstra Ida H., Kuijpers Taco W., van den Berg Timo K., Matlung Hanke L. Neutrophils in cancer Immunological reviews 2016;273 (1):312-328 [PubMed]
  • Gazendam Roel P., van de Geer Annemarie, van Hamme John L., Helgers Leanne, Rohr Jan, Chrabieh Maya, Picard Capucine, Roos Dirk, van den Berg J. Merlijn, van den Berg T. K., Kuijpers Taco W. Proinflammatory cytokine response toward fungi but not bacteria in chronic granulomatous disease Journal of allergy and clinical immunology 2016;138 (3):928-+ [PubMed]
  • Meinders Marjolein, Hoogenboezem Mark, Scheenstra Maaike R., de Cuyper Iris M., Papadopoulos Petros, Németh Tamás, Mócsai Attila, van den Berg Timo K., Kuijpers Taco W., Gutiérrez Laura Repercussion of Megakaryocyte-Specific Gata1 Loss on Megakaryopoiesis and the Hematopoietic Precursor Compartment PLoS ONE 2016;11 (5):e0154342 [PubMed]
  • Szilagyi Katka Role of inflammation in development of atherosclerosis 2016. 191p. [UvA Dissertations Online] Vrije Universiteit Amsterdam: VUmc. (Supervisors: Kraal G., de Winther M. P. J.; Co-supervisor: van den Berg T. K.)

2015

  • Scheenstra Maaike R., Salunkhe Vishal, de Cuyper Iris M., Hoogenboezem Mark, Li Eveline, Kuijpers Taco W., van den Berg Timo K., Gutiérrez Laura Characterization of hematopoietic GATA transcription factor expression in mouse and human dendritic cells Blood cells, molecules & diseases 2015;55 (4):293-303 [PubMed]
  • Szilagyi Katka, Gijbels Marion J. J., van der Velden Saskia, Heinsbroek Sigrid E. M., Kraal Georg, de Winther Menno P. J., van den Berg Timo K. Dectin-1 deficiency does not affect atherosclerosis development in mice Atherosclerosis 2015;239 (2):318-321 [PubMed]
  • Kostova Elena B., Beuger Boukje M., Klei Thomas R. L., Halonen Pasi, Lieftink Cor, Beijersbergen Roderick, van den Berg Timo K., van Bruggen Robin Identification of signalling cascades involved in red blood cell shrinkage and vesiculation Bioscience reports 2015;35 (2):e00187 [PubMed]
  • Hoeksema Marten A., Scicluna Brendon P., Boshuizen Marieke C. S., van der Velden Saskia, Neele Annette E., van den Bossche Jan, Matlung Hanke L., van den Berg Timo K., Goossens Pieter, de Winther Menno P. J. IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment Journal of immunology (Baltimore, Md. 2015;194 (8):3909-3916 [PubMed]
  • Szilagyi Katka, Gazendam Roel P., van Hamme John L., Tool Anton T. J., van Houdt Michel, Vos Wilhelm A. J. W., Verkuijlen Paul, Janssen Hans, Belot Alexandre, Juillard Laurent, Förster-Waldl Elisabeth, Boztug Kaan, Kraal Georg, de Winther Menno P. J., Kuijpers Taco W., van den Berg Timo K. Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency Journal of allergy and clinical immunology 2015;136 (5):1404-7.e1-10 [PubMed]
  • Kostova Elena B., Beuger Boukje M., Veldthuis Martijn, van der Werff ten Bosch Jutte, Kühnle Ingrid, van den Akker Emile, van den Berg Timo K., van Zwieten Rob, van Bruggen Robin Intrinsic defects in erythroid cells from familial hemophagocytic lymphohistiocytosis type 5 patients identify a role for STXBP2/Munc18-2 in erythropoiesis and phospholipid scrambling Experimental hematology 2015;43 (12):1072-1076 [PubMed]
  • Vendelbosch S., de Boer M., van der Heijde D., van den Berg T. K., van Gaalen F. A., Kuijpers T. W. KIR3DL1 and KIR3DL2 gene copy number variation in axial spondyloarthritis Tissue antigens 2015;85 (6):497-498 [PubMed]
  • van den Berg Timo K., van Bruggen Robin Loss of CD47 Makes Dendritic Cells See Red Immunity 2015;43 (4):622-624 [PubMed]
  • Nagelkerke S. Q., Tacke C. E., Breunis W. B., Geissler J., Sins J. W. R., Appelhof B., van den Berg T. K., de Boer M., Kuijpers T. W. Nonallelic homologous recombination of the FCGR2/3 locus results in copy number variation and novel chimeric FCGR2 genes with aberrant functional expression Genes and immunity 2015;16 (6):422-429 [PubMed]
  • Vendelbosch S., de Boer M., van Leeuwen K., Pourfarzad F., Geissler J., van den Berg T. K., Kuijpers T. W. Novel insights in the genomic organization and hotspots of recombination in the human KIR locus through analysis of intergenic regions Genes and immunity 2015;16 (2):103-111 [PubMed]
  • Alvarez-Zarate Julian, Matlung Hanke L., Matozaki Takashi, Kuijpers Taco W., Maridonneau-Parini Isabelle, van den Berg Timo K. Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling PLoS ONE 2015;10 (6):e0127178 [PubMed]
  • Meinders Marjolein, Kulu Divine I., van de Werken Harmen J. G., Hoogenboezem Mark, Janssen Hans, Brouwer Rutger W. W., van Ijcken Wilfred F. J., Rijkers Erik-Jan, Demmers Jeroen A. A., Krüger Imme, van den Berg Timo K., Suske Guntram, Gutiérrez Laura, Philipsen Sjaak Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function Blood 2015;125 (12):1957-1967 [PubMed]
  • Vendelbosch S., Heslinga S. C., John M., van Leeuwen K., Geissler J., de Boer M., Tanck M. W. T., van den Berg T. K., Crusius J. B. A., van der Horst-Bruinsma I. E., Kuijpers T. W. Study on the protective effect of the KIR3DL1 gene in ankylosing spondylitis Arthritis & rheumatology (Hoboken, N.J.) 2015;67 (11):2957-2965 [PubMed]
  • Kooij Gijs, Braster Rens, Koning Jasper J., Laan Lisa C., van Vliet Sandra J., Los Tamara, Eveleens Anne Marieke, van der Pol Susanne M. A., Förster-Waldl Elisabeth, Boztug Kaan, Belot Alexandre, Szilagyi Katka, van den Berg Timo K., van Buul Jaap D., van Egmond Marjolein, de Vries Helga E., Cummings Richard D., Dijkstra Christine D., van Die Irma Trichuris suis induces human non-classical patrolling monocytes via the mannose receptor and PKC: implications for multiple sclerosis Acta neuropathologica communications 2015;3 (1):45 [PubMed]
  • Vendelbosch Sanne Unraveling the genetic expression of the highly variable immune receptors of a killer 2015. 158p. ISBN 9789461825759. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers T. W.; Co-supervisor: van den Berg T. K.)

2014

  • Nagelkerke Sietse Quirijn, Aan de Kerk Daan Jacob, Jansen Machiel Hugo, van den Berg Timo Kars, Kuijpers Taco Willem Failure to detect functional neutrophil B helper cells in the human spleen PLoS ONE 2014;9 (2):e88377 [PubMed]
  • van der Heijden Joris Genetic variation in human Fc gamma receptors: Functional consequences of polymorphisms and copy number variation 2014. 163p. ISBN 9789461824592. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers T. W.; Co-supervisor: van den Berg T. K.)
  • van der Heijden Joris, Nagelkerke Sietse, Zhao Xiwen, Geissler Judy, Rispens Theo, van den Berg Timo K., Kuijpers Taco W. Haplotypes of FcγRIIa and FcγRIIIb polymorphic variants influence IgG-mediated responses in neutrophils Journal of immunology (Baltimore, Md. 2014;192 (6):2715-2721 [PubMed]
  • Canault Matthias, Ghalloussi Dorsaf, Grosdidier Charlotte, Guinier Marie, Perret Claire, Chelghoum Nadjim, Germain Marine, Raslova Hana, Peiretti Franck, Morange Pierre E., Saut Noemie, Pillois Xavier, Nurden Alan T., Cambien François, Pierres Anne, van den Berg Timo K., Kuijpers Taco W., Alessi Marie-Christine, Tregouet David-Alexandre Human CalDAG-GEFI gene (RASGRP2) mutation affects platelet function and causes severe bleeding Journal of experimental medicine 2014;211 (7):1349-1362 [PubMed]
  • Nagelkerke Sietse Q., Dekkers Gillian, Kustiawan Iwan, van de Bovenkamp Fleur S., Geissler Judy, Plomp Rosina, Wuhrer Manfred, Vidarsson Gestur, Rispens Theo, van den Berg Timo K., Kuijpers Taco W. Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages Blood 2014;124 (25):3709-3718 [PubMed]
  • van de Vijver Edith, Tool Anton T. J., Sanal Özden, Çetin Mualla, Ünal Sule, Aytac Selin, Seeger Karl, Pagliara Daria, Rutella Sergio, van den Berg Timo K., Kuijpers Taco W. Kindlin-3-independent adhesion of neutrophils from patients with leukocyte adhesion deficiency type III Journal of allergy and clinical immunology 2014;133 (4):1215-1218 [PubMed]
  • de Back Djuna Z., Kostova Elena B., van Kraaij Marian, van den Berg Timo K., van Bruggen Robin Of macrophages and red blood cells; a complex love story Frontiers in physiology 2014;5:9 [PubMed]
  • Szilagyi Katka, Meijer Alexander B., Neele Annette E., Verkuijlen Paul, Leitges Michael, Dabernat Sandrine, Förster-Waldl Elisabeth, Boztug Kaan, Belot Alexandre, Kuijpers Taco W., Kraal Georg, de Winther Menno P. J., van den Berg Timo K. PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages Cardiovascular research 2014;104 (3):467-476 [PubMed]
  • de Boer Martin, van Leeuwen Karin, Geissler Judy, Weemaes Corry M., van den Berg Timo K., Kuijpers Taco W., Warris Adilia, Roos Dirk Primary immunodeficiency caused by an exonized retroposed gene copy inserted in the CYBB gene Human mutation 2014;35 (4):486-496 [PubMed]
  • Zhao Xi Wen Targeting CD47-SIRPα interactions for potentiating therapeutic antibody-mediated tumor cell destruction by phagocytes 2014. 149p. ISBN 9789462592384. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers T. W.; Co-supervisor: van den Berg T. K.)
  • Barclay A. Neil, van den Berg Timo K. The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target Annual review of immunology 2014;32:25-50 [PubMed]
  • Alvarez Zarate Julian The phagocyte inhibitory receptor sirpα in the immune system 2014. 148p. ISBN 9789461824950. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers T. W.; Co-supervisor: van den Berg T. K.)
  • Gazendam Roel P., van Hamme John L., Tool Anton T. J., van Houdt Michel, Verkuijlen Paul J. J. H., Herbst Martin, Liese Johannes G., van de Veerdonk Frank L., Roos Dirk, van den Berg Timo K., Kuijpers Taco W. Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects Blood 2014;124 (4):590-597 [PubMed]

2013

  • de Cuyper Iris M., Meinders Marjolein, van de Vijver Edith, de Korte Dirk, Porcelijn Leendert, de Haas Masja, Eble Johannes A., Seeger Karl, Rutella Sergio, Pagliara Daria, Kuijpers Taco W., Verhoeven Arthur J., van den Berg Timo K., Gutiérrez Laura A novel flow cytometry-based platelet aggregation assay Blood 2013;121 (10):E70-E80 [PubMed]
  • van der Heijden Joris, Geissler Judy, van Mirre Edwin, van Deuren Marcel, van der Meer Jos W. M., Salama Abdulgabar, van den Berg Timo K., Roos Dirk, Kuijpers Taco W. A novel splice variant of FcγRIIa: a risk factor for anaphylaxis in patients with hypogammaglobulinemia Journal of allergy and clinical immunology 2013;131 (5):1408-16.e5 [PubMed]
  • Szilagyi Katka, van den Berg Timo K. A role for PKCδ in foam cell formation? Cardiovascular research 2013;97 (2):389 [PubMed]
  • Zhao Xi Wen, Gazendam Roel P., Drewniak Agata, van Houdt Michel, Tool Anton T. J., van Hamme John L., Kustiawan Iwan, Meijer Alexander B., Janssen Hans, Russell David G., van de Corput Lisette, Tesselaar Kiki, Boelens Jaap J., Kuhnle Ingrid, van der Werff ten Bosch Jutte, Kuijpers Taco W., van den Berg Timo K. Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations Blood 2013;122 (1):109-111 [PubMed]
  • Irandoust Mahban, Alvarez Zarate Julian, Hubeek Isabelle, van Beek Ellen M., Schornagel Karin, Broekhuizen Aart J. F., Akyuz Mercan, van de Loosdrecht Arjan A., Delwel Ruud, Valk Peter J., Sonneveld Edwin, Kearns Pamela, Creutzig Ursula, Reinhardt Dirk, de Bont Eveline S. J. M., Coenen Eva A., van den Heuvel-Eibrink Marry M., Zwaan C. Michel, Kaspers Gertjan J. L., Cloos Jacqueline, van den Berg Timo K. Engagement of SIRPα inhibits growth and induces programmed cell death in acute myeloid leukemia cells PLoS ONE 2013;8 (1):e52143 [PubMed]
  • Vendelbosch Sanne, de Boer Martin, Gouw Remko A. T. W., Ho Cynthia K. Y., Geissler Judy, Swelsen Wendy T. N., Moorhouse Michael J., Lardy Neubury M., Roos Dirk, van den Berg Timo K., Kuijpers Taco W. Extensive variation in gene copy number at the killer immunoglobulin-like receptor locus in humans PLoS ONE 2013;8 (6):e67619 [PubMed]
  • Drewniak Agata, Gazendam Roel P., Tool Anton T. J., van Houdt Michel, Jansen Machiel H., van Hamme John L., van Leeuwen Ester M. M., Roos Dirk, Scalais Emmanuel, de Beaufort Carine, Janssen Hans, van den Berg Timo K., Kuijpers Taco W. Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency Blood 2013;121 (13):2385-2392 [PubMed]
  • van de Vijver Edith Kindlin-3 in hematopoietic integrin activation: absense in leucyte adhesion deficiency type III 2013. 155p. ISBN 9789461822888. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kuijpers T. W.; Co-supervisors: van den Berg T. K., Roos D.)
  • van de Vijver Edith, van den Berg Timo K., Kuijpers Taco W. Leukocyte adhesion deficiencies Hematology/oncology clinics of North America 2013;27 (1):101-16, viii [PubMed]
  • Zhao Xiwen, Matlung Hanke, Kuijpers Taco W., van den Berg Timo K. On the mechanism and benefit of siRNA-mediated targeting of CD47 in cancer Molecular therapy 2013;21 (10):1811-1812 [PubMed]
  • Burger Patrick, Kostova Elena, Bloem Esther, Hilarius-Stokman Petra, Meijer Alexander B., van den Berg Timo K., Verhoeven Arthur J., de Korte Dirk, van Bruggen Robin Potassium leakage primes stored erythrocytes for phosphatidylserine exposure and shedding of pro-coagulant vesicles British journal of haematology 2013;160 (3):377-386 [PubMed]
  • O'Neill Alexander S. G., van den Berg Timo K., Mullen Gregory E. D. Sialoadhesin - a macrophage-restricted marker of immunoregulation and inflammation Immunology 2013;138 (3):198-207 [PubMed]
  • Samson Thomas, van Buul Jaap D., Kroon Jeffrey, Welch Christopher, Bakker Erik N., Matlung Hanke L., van den Berg Timo K., Sharek Lisa, Doerschuk Claire, Hahn Klaus, Burridge Keith The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis PLoS ONE 2013;8 (1):e55202 [PubMed]

2012

  • Burger Patrick, Hilarius-Stokman Petra, de Korte Dirk, van den Berg Timo K., van Bruggen Robin CD47 functions as a molecular switch for erythrocyte phagocytosis Blood 2012;119 (23):5512-5521 [PubMed]
  • Burger Patrick, de Korte Dirk, van den Berg Timo K., van Bruggen Robin CD47 in Erythrocyte Ageing and Clearance - the Dutch Point of View Transfusion medicine and hemotherapy 2012;39 (5):348-352 [PubMed]
  • van de Vijver Edith, de Cuyper Iris M., Gerrits Anja J., Verhoeven Arthur J., Seeger Karl, Gutiérrez Laura, van den Berg Timo K., Kuijpers Taco W. Defects in Glanzmann thrombasthenia and LAD-III (LAD-1/v) syndrome: the role of integrin beta 1 and beta 3 in platelet adhesion to collagen Blood 2012;119 (2):583-586 [PubMed]
  • Kenzel Sybille, Mergen Miriam, von Süßkind-Schwendi Julius, Wennekamp Julia, Deshmukh Sachin D., Haeffner Monika, Triantafyllopoulou Antigoni, Fuchs Sebastian, Farmand Susan, Santos-Sierra Sandra, Seufert Jochen, van den Berg Timo K., Kuijpers Taco W., Henneke Philipp Insulin Modulates the Inflammatory Granulocyte Response to Streptococci via Phosphatidylinositol 3-Kinase Journal of immunology (Baltimore, Md. 2012;189 (9):4582-4591 [PubMed]
  • Zhao Xi Wen, Kuijpers Taco W., van den Berg Timo K. Is targeting of CD47-SIRP alpha enough for treating hematopoietic malignancy? Blood 2012;119 (18):4333-4334 [PubMed]
  • Zhao Xi Wen, Matlung Hanke L., Kuijpers Taco W., van den Berg Timo K. On the mechanism of CD47 targeting in cancer Proceedings of the National Academy of Sciences of the United States of America 2012;109 (42):E2843-E2843; author reply E2845 [PubMed]
  • van der Heijden Joris, Breunis Willemijn B., Geissler Judy, de Boer Martin, van den Berg Timo K., Kuijpers Taco W. Phenotypic Variation in IgG Receptors by Nonclassical FCGR2C Alleles Journal of immunology (Baltimore, Md. 2012;188 (3):1318-1324 [PubMed]
  • van Beek Ellen M., Zarate Julian Alvarez, van Bruggen Robin, Schornagel Karin, Tool Anton T. J., Matozaki Takashi, Kraal Georg, Roos Dirk, van den Berg Timo K. SIRP alpha Controls the Activity of the Phagocyte NADPH Oxidase by Restricting the Expression of gp91(phox) Cell reports 2012;2 (4):748-755 [PubMed]

2011

  • Orelio Claudia, van der Sluis Renée M., Verkuijlen Paul, Nethe Micha, Hordijk Peter L., van den Berg Timo K., Kuijpers Taco W. Altered intracellular localization and mobility of SBDS protein upon mutation in Shwachman-Diamond syndrome PLoS ONE 2011;6 (6):e20727 [PubMed]
  • Zhao Xi Wen, van Beek Ellen M., Schornagel Karin, van der Maaden Hans, van Houdt Michel, Otten Marielle A., Finetti Pascal, van Egmond Marjolein, Matozaki Takashi, Kraal Georg, Birnbaum Daniel, van Elsas Andrea, Kuijpers Taco W., Bertucci Francois, van den Berg Timo K. CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction Proceedings of the National Academy of Sciences of the United States of America 2011;108 (45):18342-18347 [PubMed]
  • Leito Jelani T. D., Ligtenberg Antoon J. M., van Houdt Michel, van den Berg Timo K., Wouters Diana The bacteria binding glycoprotein salivary agglutinin (SAG/gp340) activates complement via the lectin pathway Molecular immunology 2011;49 (1-2):185-190 [PubMed]

2010

  • van Bruggen Robin, Köker M. Yavuz, Jansen Machiel, van Houdt Michel, Roos Dirk, Kuijpers Taco W., van den Berg Timo K. Human NLRP3 inflammasome activation is Nox1-4 independent Blood 2010;115 (26):5398-5400 [PubMed]
  • van den Berg Timo K. On the origin and function of immune 'self' recognition Immunology letters 2010;128 (1):24-25 [PubMed]
  • Drewniak Agata, Tool Anton T. J., Geissler Judy, van Bruggen Robin, van den Berg Timo K., Kuijpers Taco W. Toll-like receptor-induced reactivity and strongly potentiated IL-8 production in granulocytes mobilized for transfusion purposes Blood 2010;115 (22):4588-4596 [PubMed]
  • van Bruggen Robin, Drewniak Agata, Tool Anton T. J., Jansen Machiel, van Houdt Michel, Geissler Judy, van den Berg Timo K., Chapel Helen, Kuijpers Taco W. Toll-Like Receptor Responses in IRAK-4-Deficient Neutrophils Journal of innate immunity 2010;2 (3):280-287 [PubMed]

2009

  • Drewniak Agata, van Raam Bram J., Geissler Judy, Tool Anton T. J., Mook Olaf R. F., van den Berg Timo K., Baas Frank, Kuijpers Taco W. Changes in gene expression of granulocytes during in vivo granulocyte colony-stimulating factor/dexamethasone mobilization for transfusion purposes Blood 2009;113 (23):5979-5998 [PubMed]
  • van Beek Ellen M., de Vries Teun J., Mulder Lars, Schoenmaker Ton, Hoeben Kees A., Matozaki Takashi, Langenbach Geerling E. J., Kraal Georg, Everts Vincent, van den Berg Timo K. Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha FASEB journal 2009;23 (12):4081-4090 [PubMed]
  • Kuijpers Taco W., van de Vijver Edith, Weterman Marian A. J., de Boer Martin, Tool Anton T. J., van den Berg Timo K., Moser Markus, Jakobs Marja E., Seeger Karl, Sanal Ozden, Unal Sule, Cetin Mualla, Roos Dirk, Verhoeven Arthur J., Baas Frank LAD-1/variant syndrome is caused by mutations in FERMT3 Blood 2009;113 (19):4740-4746 [PubMed]
  • Irandoust Mahban, van den Berg Timo K., Kaspers Gertjan J. L., Cloos Jacqueline Role of tyrosine phosphatase inhibitors in cancer treatment with emphasis on SH2 domain-containing tyrosine phosphatases (SHPs) Anti-cancer agents in medicinal chemistry 2009;9 (2):212-220 [PubMed]
  • Orelio Claudia, Verkuijlen Paul, Geissler Judy, van den Berg Timo K., Kuijpers Taco W. SBDS expression and localization at the mitotic spindle in human myeloid progenitors PLoS ONE 2009;4 (9):e7084 [PubMed]
  • van Beek Ellen M. Signal regulatory protein alpha in phagocyte function 2009. 192p. [UvA Dissertations Online] Amsterdam UMC - Vrije Universiteit Amsterdam. (Supervisors: Dijkstra C. D., Kraal G.; Co-supervisor: van den Berg T. K.)
  • Fabriek Babs O., van Bruggen Robin, Deng Dong Mei, Ligtenberg Antoon J. M., Nazmi Kamran, Schornagel Karin, Vloet Rianka P. M., Dijkstra Christine D., van den Berg Timo K. The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria Blood 2009;113 (4):887-892 [PubMed]

2008

  • van Raam Bram J., Drewniak Agata, Groenewold Vincent, van den Berg Timo K., Kuijpers Taco W. Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3 Blood 2008;112 (5):2046-2054 [PubMed]
  • van den Berg Timo K., van der Schoot C. Ellen Innate immune 'self' recognition: a role for CD47-SIRP alpha interactions in hematopoietic stem cell transplantation Trends in immunology 2008;29 (5):203-206 [PubMed]
  • Fabriek Babs O. Perivascular macrophages in neuroinflammation, the role of the scavenger receptor CD163 2008. 207p. [UvA Dissertations Online] Amsterdam UMC - Vrije Universiteit Amsterdam. (Supervisor: Dijkstra C. D.; Co-supervisor: van den Berg T. K.)
  • van Manen Henk-Jan, Verkuijlen Paul, Wittendorp Paul, Subramaniam Vinod, van den Berg Timo K., Roos Dirk, Otto Cees Refractive index sensing of green fluorescent proteins in living cells using fluorescence lifetime imaging microscopy Biophysical journal 2008;94 (8):L67-L69 [PubMed]

2007

  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Polfliet Machteld M. J., van den Berg Timo K., Dijkstra Christine D., Roord John J., Hack C. Erik, van Furth A. Marceline C1 inhibitor treatment improves host defense in pneumococcal meningitis in rats and mice Journal of infectious diseases 2007;196 (1):115-123 [PubMed]
  • Xu Wei, Schlagwein Nicole, Roos Anja, van den Berg Timo K., Daha Mohamed R., van Kooten Cees Human peritoneal macrophages show functional characteristics of M-CSF-driven anti-inflammatory type 2 macrophages European journal of immunology 2007;37 (6):1594-1599 [PubMed]
  • Fabriek Babs O., Møller Holger J., Vloet Rianka P. M., van Winsen Lisa M., Hanemaaijer Roeland, Teunissen Charlotte E., Uitdehaag Bernard M. J., van den Berg Timo K., Dijkstra Christine D. Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis Journal of neuroimmunology 2007;187 (1-2):179-186 [PubMed]
  • Fabriek Babs O., Polfliet Machteld M. J., Vloet Rianka P. M., van der Schors Roel C., Ligtenberg Antoon J. M., Weaver Lehn K., Geest Christiaan, Matsuno Kenjiro, Moestrup Søren K., Dijkstra Christien D., van den Berg Timo K. The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor Blood 2007;109 (12):5223-5229 [PubMed]

2006

  • Polfliet Machteld M. J., Fabriek Babs O., Daniëls Wouter P., Dijkstra Christine D., van den Berg Timo K. The rat macrophage scavenger receptor CD163: expression, regulation and role in inflammatory mediator production Immunobiology 2006;211 (6-8):419-425 [PubMed]

2005

  • van den Berg Timo K., Kraal Georg A function for the macrophage F4/80 molecule in tolerance induction Trends in immunology 2005;26 (10):506-509 [PubMed]
  • van den Berg Timo K., van Beek Ellen M., Bühring Hans-Jörg, Colonna Marco, Hamaguchi Michinari, Howard Chris J., Kasuga Masato, Liu Yuan, Matozaki Takashi, Neel Benjamin G., Parkos Charles A., Sano Shin-ichiro, Vignery Agnès, Vivier Eric, Wright Mark, Zawatzky Rainer, Barclay A. Neil A nomenclature for signal regulatory protein family members Journal of immunology (Baltimore, Md. 2005;175 (12):7788-7789 [PubMed]
  • Fabriek Babs O., van Haastert Elise S., Galea Ian, Polfliet Machteld M. J., Döpp Ed D., van den Heuvel Michel M., van den Berg Timo K., de Groot Corline J. A., van der Valk Paul, Dijkstra Christine D. CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation Glia 2005;51 (4):297-305 [PubMed]
  • van Winsen Lisa M. L., Muris Daan F. R., Polman Chris H., Dijkstra Christine D., van den Berg Timo K., Uitdehaag Bernard M. J. Sensitivity to glucocorticoids is decreased in relapsing remitting multiple sclerosis Journal of clinical endocrinology and metabolism 2005;90 (2):734-740 [PubMed]
  • Alblas Jacqueline, Honing Henk, de Lavalette Chantal Renardel, Brown Marion H., Dijkstra Christine D., van den Berg Timo K. Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways Molecular and cellular biology 2005;25 (16):7181-7192 [PubMed]
  • van Beek Ellen M., Cochrane Fiona, Barclay A. Neil, van den Berg Timo K. Signal regulatory proteins in the immune system Journal of immunology (Baltimore, Md. 2005;175 (12):7781-7787 [PubMed]
  • van Winsen Lisa L. M., Hooper-van Veen Tineke, van Rossum Elisabeth F. C., Polman Chris H., van den Berg Timo K., Koper Jan W., Uitdehaag Bernard M. J. The impact of glucocorticoid receptor gene polymorphisms on glucocorticoid sensitivity is outweighted in patients with multiple sclerosis Journal of neuroimmunology 2005;167 (1-2):150-156 [PubMed]
  • Fabriek Babs O., Dijkstra Christine D., van den Berg Timo K. The macrophage scavenger receptor CD163 Immunobiology 2005;210 (2-4):153-160 [PubMed]

2004

  • van den Berg Timo K., Honing Henk, Franke Niels, van Remoortere Alexandra, Schiphorst Wietske E. C. M., Liu Fu-Tong, Deelder André M., Cummings Richard D., Hokke Cornelis H., van Die Irma LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition Journal of immunology (Baltimore, Md. 2004;173 (3):1902-1907 [PubMed]
  • van den Berg Timo K., Yoder Jeffrey A., Litman Gary W. On the origins of adaptive immunity: innate immune receptors join the tale Trends in immunology 2004;25 (1):11-16 [PubMed]
  • Honing Henk, van den Berg Timo K., van der Pol Susanne M. A., Dijkstra Christine D., van der Kammen Rob A., Collard John G., de Vries Helga E. RhoA activation promotes transendothelial migration of monocytes via ROCK Journal of leukocyte biology 2004;75 (3):523-528 [PubMed]

2003

  • van Rijn J., van den Berg J., Teerlink T., Kruyt F. A. E., Schor D. S. M., Renardel de Lavalette A. C., van den Berg T. K., Jakobs C., Slotman B. J. Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells British journal of cancer 2003;88 (3):447-454 [PubMed]
  • Zwijnenburg Petra J. G., Polfliet Machteld M. J., Florquin Sandrine, van den Berg Timo K., Dijkstra Christine D., van Deventer Sander J. H., Roord John J., van der Poll Tom, van Furth A. Marceline CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats Immunology letters 2003;85 (1):1-4 [PubMed]
  • Hendriks Jerome J. A., de Vries Helga E., van der Pol Susanne M. A., van den Berg Timo K., van Tol Eric A. F., Dijkstra Christine D. Flavonoids inhibit myelin phagocytosis by macrophages; a structure-activity relationship study Biochemical pharmacology 2003;65 (5):877-885 [PubMed]
  • Ledeboer Annemarie, Wierinckx Anne, Bol John G. J. M., Floris Sarah, Renardel de Lavalette Chantal, de Vries Helga E., van den Berg Timo K., Dijkstra Christine D., Tilders Fred J. H., van Dam Anne-Marie Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE Journal of neuroimmunology 2003;136 (1-2):94-103 [PubMed]

2002

  • de Vries Helga E., Hendriks Jerome J. A., Honing Henk, de Lavalette Chantal Renardel, van der Pol Susanne M. A., Hooijberg Erik, Dijkstra Christine D., van den Berg Timo K. Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium Journal of immunology (Baltimore, Md. 2002;168 (11):5832-5839 [PubMed]
  • Polfliet Machteld M. J., van de Veerdonk F., Döpp Ed A., van Kesteren-Hendrikx Esther M. L., van Rooijen Nico, Dijkstra Christine D., van den Berg Timo K. The role of perivascular and meningeal macrophages in experimental allergic encephalomyelitis Journal of neuroimmunology 2002;122 (1-2):1-8 [PubMed]

2001

  • Polfliet M. M., Goede P. H., van Kesteren-Hendrikx E. M., van Rooijen N., Dijkstra C. D., van den Berg T. K. A method for the selective depletion of perivascular and meningeal macrophages in the central nervous system Journal of neuroimmunology 2001;116 (2):188-195 [PubMed]
  • van den Berg T. K., Nath D., Ziltener H. J., Vestweber D., Fukuda M., van Die I., Crocker P. R. Cutting edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1) Journal of immunology (Baltimore, Md. 2001;166 (6):3637-3640 [PubMed]
  • van den Nieuwenhof I. M., Renardel de Lavalette C., Diaz N., van Die I., van den Berg T. K. Differential galactosylation of neuronal and haematopoietic signal regulatory protein-alpha determines its cellular binding-specificity Journal of cell science 2001;114 (Part 7):1321-1329 [PubMed]
  • Polfliet M. M., Zwijnenburg P. J., van Furth A. M., van der Poll T., Döpp E. A., Renardel de Lavalette C., van Kesteren-Hendrikx E. M., van Rooijen N., Dijkstra C. D., van den Berg T. K. Meningeal and perivascular macrophages of the central nervous system play a protective role during bacterial meningitis Journal of immunology (Baltimore, Md. 2001;167 (8):4644-4650 [PubMed]
  • van den Berg T. K., Puklavec M. J., Barclay A. N., Dijkstra C. D. Monoclonal antibodies against rat leukocyte surface antigens Immunological reviews 2001;184:109-116 [PubMed]
  • van den Berg T. K., Döpp E. A., Dijkstra C. D. Rat macrophages: membrane glycoproteins in differentiation and function Immunological reviews 2001;184:45-57 [PubMed]

2000

  • van der Goes A., Hoekstra K., van den Berg T. K., Dijkstra C. D. Dexamethasone promotes phagocytosis and bacterial killing by human monocytes/macrophages in vitro Journal of leukocyte biology 2000;67 (6):801-807 [PubMed]
  • Verhage M., Maia A. S., Plomp J. J., Brussaard A. B., Heeroma J. H., Vermeer H., Toonen R. F., Hammer R. E., van den Berg T. K., Missler M., Geuze H. J., Südhof T. C. Synaptic assembly of the brain in the absence of neurotransmitter secretion Science 2000;287 (5454):864-869 [PubMed]
  • Khouw I. M., van Wachem P. B., van der Worp R. J., van den Berg T. K., de Leij L. F., van Luyn M. J. Systemic anti-IFN-gamma treatment and role of macrophage subsets in the foreign body reaction to dermal sheep collagen in rats Journal of biomedical materials research 2000;49 (3):297-304 [PubMed]
  • Schadee-Eestermans I. L., Hoefsmit E. C., van de Ende M., Crocker P. R., van den Berg T. K., Dijkstra C. D. Ultrastructural localisation of sialoadhesin (siglec-1) on macrophages in rodent lymphoid tissues Immunobiology 2000;202 (4):309-325 [PubMed]

1999

  • van Die I., Gomord V., Kooyman F. N., van den Berg T. K., Cummings R. D., Vervelde L. Core alpha1-->3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus infected sheep FEBS letters 1999;463 (1-2):189-193 [PubMed]
  • Jansen J., Uitdehaag B., Koper J. W., van den Berg T. K. Glucocorticoid receptor ligand binding in monocytic cells using a microplate assay Pathobiology 1999;67 (5-6):262-264 [PubMed]
  • van den Heuvel M. M., Tensen C. P., van As J. H., van den Berg T. K., Fluitsma D. M., Dijkstra C. D., Döpp E. A., Droste A., van Gaalen F. A., Sorg C., Högger P., Beelen R. H. Regulation of CD 163 on human macrophages: cross-linking of CD163 induces signaling and activation Journal of leukocyte biology 1999;66 (5):858-866 [PubMed]

1998

  • Hazenbos W. L., Heijnen I. A., Meyer D., Hofhuis F. M., Renardel de Lavalette C. R., Schmidt R. E., Capel P. J., van de Winkel J. G., Gessner J. E., van den Berg T. K., Verbeek J. S. Murine IgG1 complexes trigger immune effector functions predominantly via Fc gamma RIII (CD16) Journal of immunology (Baltimore, Md. 1998;161 (6):3026-3032 [PubMed]
  • van der Goes A., Brouwer J., Hoekstra K., Roos D., van den Berg T. K., Dijkstra C. D. Reactive oxygen species are required for the phagocytosis of myelin by macrophages Journal of neuroimmunology 1998;92 (1-2):67-75 [PubMed]
  • Crocker P. R., Clark E. A., Filbin M., Gordon S., Jones Y., Kehrl J. H., Kelm S., Le Douarin N., Powell L., Roder J., Schnaar R. L., Sgroi D. C., Stamenkovic K., Schauer R., Schachner M., van den Berg T. K., van der Merwe P. A., Watt S. M., Varki A. Siglecs: a family of sialic-acid binding lectins Glycobiology 1998;8 (2):v [PubMed]
  • Adams S., van der Laan L. J., Vernon-Wilson E., Renardel de Lavalette C., Döpp E. A., Dijkstra C. D., Simmons D. L., van den Berg T. K. Signal-regulatory protein is selectively expressed by myeloid and neuronal cells Journal of immunology (Baltimore, Md. 1998;161 (4):1853-1859 [PubMed]

1997

  • Veerman E. C., Bolscher J. G., Appelmelk B. J., Bloemena E., van den Berg T. K., Nieuw Amerongen A. V. A monoclonal antibody directed against high M(r) salivary mucins recognizes the SO3-3Gal beta 1-3GlcNAc moiety of sulfo-Lewis(a): a histochemical survey of human and rat tissue Glycobiology 1997;7 (1):37-43 [PubMed]

1996

  • van Rooijen N., Sanders A., van den Berg T. K. Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine Journal of immunological methods 1996;193 (1):93-99 [PubMed]
  • Kruyt F. A., Dijkmans L. M., van den Berg T. K., Joenje H. Fanconi anemia genes act to suppress a cross-linker-inducible p53-independent apoptosis pathway in lymphoblastoid cell lines Blood 1996;87 (3):938-948 [PubMed]
  • van den Berg T. K., Hasbold J., Renardel de Lavalette C., Döpp E. A., Dijkstra C. D., Klaus G. G. Properties of mouse CD40: differential expression of CD40 epitopes on dendritic cells and epithelial cells Immunology 1996;88 (2):294-300 [PubMed]
  • van den Berg T. K., van Die I., de Lavalette C. R., Döpp E. A., Smit L. D., van der Meide P. H., Tilders F. J., Crocker P. R., Dijkstra C. D. Regulation of sialoadhesin expression on rat macrophages. Induction by glucocorticoids and enhancement by IFN-beta, IFN-gamma, IL-4, and lipopolysaccharide Journal of immunology (Baltimore, Md. 1996;157 (7):3130-3138 [PubMed]

1995

  • Yoshida K., Kaji M., Takahashi T., van den Berg T. K., Dijkstra C. D. Host origin of follicular dendritic cells induced in the spleen of SCID mice after transfer of allogeneic lymphocytes Immunology 1995;84 (1):117-126 [PubMed]
  • van den Berg T. K., Yoshida K., Dijkstra C. D. Mechanism of immune complex trapping by follicular dendritic cells Current topics in microbiology and immunology 1995;201:49-67 [PubMed]
  • Biewenga J., van Poppel M. N., van den Berg T. K., van Rees E. P., Sminia T. Reticulum cells in the ontogeny of nasal-associated lymphoid tissue (NALT) in the rat Advances in experimental medicine and biology 1995;371A:407-410 [PubMed]

1994

  • Dijkstra C. D., Döpp E. A., van den Berg T. K., Damoiseaux J. G. Monoclonal antibodies against rat macrophages Journal of immunological methods 1994;174 (1-2):21-23 [PubMed]
  • Yoshida K., van den Berg T. K., Dijkstra C. D. The functional state of follicular dendritic cells in severe combined immunodeficient (SCID) mice: role of the lymphocytes European journal of immunology 1994;24 (2):464-468 [PubMed]
  • Barbé E., Döpp E. A., Damoiseaux J. G., van den Berg T. K., Dijkstra C. D. The role of macrophages in regeneration of splenic tissue after autologous transplantation in rat Advances in experimental medicine and biology 1994;355:57-61 [PubMed]
  • Kraal G., Hoeben K., Brevé J., van den Berg T. K. The role of sialic acid in the localization of lymphocytes in the spleen Immunobiology 1994;190 (1-2):138-149 [PubMed]

1993

  • van den Berg T. K., van der Ende M., Döpp E. A., Kraal G., Dijkstra C. D. Localization of beta 1 integrins and their extracellular ligands in human lymphoid tissues American journal of pathology 1993;143 (4):1098-1110 [PubMed]
  • van Poppel M. N., van den Berg T. K., van Rees E. P., Sminia T., Biewenga J. Reticulum cells in the ontogeny of nasal-associated lymphoid tissue (NALT) in the rat Cell and tissue research 1993;273 (3):577-581 [PubMed]
  • Yoshida K., van den Berg T. K., Dijkstra C. D. Two different mechanisms of immune-complex trapping in the mouse spleen during immune responses Advances in experimental medicine and biology 1993;329:377-382 [PubMed]
  • Yoshida K., van den Berg T. K., Dijkstra C. D. Two functionally different follicular dendritic cells in secondary lymphoid follicles of mouse spleen, as revealed by CR1/2 and FcR gamma II-mediated immune-complex trapping Immunology 1993;80 (1):34-39 [PubMed]

1992

  • van Oostveen D. C., van den Berg T. K., Damoiseaux J. G., van Rees E. P. Macrophage subpopulations and reticulum cells in rat placenta. An immunohistochemical study Cell and tissue research 1992;268 (3):513-519 [PubMed]
  • Soesatyo M., van den Berg T. K., van Rees E. P., Biewenga J., Sminia T. Ontogeny of reticulum cells in the rat intestine and their possible role in the development of the lymphoid microenvironment Regional immunology 1992;4 (1):46-52 [PubMed]
  • van den Berg T. K., Döpp E. A., Daha M. R., Kraal G., Dijkstra C. D. Selective inhibition of immune complex trapping by follicular dendritic cells with monoclonal antibodies against rat C3 European journal of immunology 1992;22 (4):957-962 [PubMed]
  • van den Berg T. K., Brevé J. J., Damoiseaux J. G., Döpp E. A., Kelm S., Crocker P. R., Dijkstra C. D., Kraal G. Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule Journal of experimental medicine 1992;176 (3):647-655 [PubMed]

1991

  • Dijkstra C. D., van den Berg T. K. The follicular dendritic cell: possible regulatory roles of associated molecules Research in immunology 1991;142 (3):227-231 [PubMed]

1989

  • van den Berg T. K., Döpp E. A., Brevé J. J., Kraal G., Dijkstra C. D. The heterogeneity of the reticulum of rat peripheral lymphoid organs identified by monoclonal antibodies European journal of immunology 1989;19 (9):1747-1756 [PubMed]
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