Prof. Y. Pinto PhD publications

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Publications Prof. PhD Y. Pinto

Position
Full Professor
Main activities
Patient care, Research, Other
Specialisation
Cardiology
Focus of research

 My research aims at understanding why an overloaded heart ultimately fails. Our leading thought is that the transition towards failure is governed by regulatory mechanisms that cause an accumulation of maladaptive changes. Our current focus is on genetic mechanisms and mechanisms involving RNA regulatory molecuales like microRNAs, lncRNAs and RNA splicing as key regulators of the adapative and maladaptive changes in the overloaded heart.

2021

  • Bleijendaal Hidde, Ramos Lucas A, Lopes Ricardo R, Verstraelen Tom E, Baalman Sarah W E, Oudkerk Pool Marinka D, Tjong Fleur V Y, Melgarejo-Meseguer Francisco M, Gimeno-Blanes F Javier, Gimeno-Blanes Juan R, Amin Ahmad S, Winter Michiel M, Marquering Henk A, Kok Wouter E M, Zwinderman Aeilko H, Wilde Arthur A M, Pinto Yigal M Computer versus cardiologist: Is a machine learning algorithm able to outperform an expert in diagnosing a phospholamban p.Arg14del mutation on the electrocardiogram? Heart rhythm 2021;18 (1):79-87 [PubMed]

2020

  • Oudkerk Pool Marinka D., Kauw Dirkjan, Bleijendaal Hidde, Mulder Barbara J. M., Pinto Yigal, Bouma Berto J., Winter Michiel M. Artificial Intelligence in Patients with Congenital Heart Disease: Where Do We Stand? EMJ Cardiology 2020;8 (1):70-81
  • Mizia-Stec Katarzyna, Caforio Alida L. P., Charron Philippe, Gimeno Juan R., Elliott Perry, Kaski Juan Pablo, Maggioni Aldo P., Tavazzi Luigi, Rigopoulos Angelos G., Laroche Cecile, Frigy Attila, Zachara Elisabetta, Pena-Pena Maria Luisa, Olusegun-Joseph Akinsanya, Pinto Yigal, Sala Simone, Drago Fabrizio, Blagova Olga, Reznik Elena, Tendera Michał Atrial fibrillation, anticoagulation management and risk of stroke in the Cardiomyopathy/Myocarditis registry of the EURObservational Research Programme of the European Society of Cardiology ESC heart failure 2020;7 (6):3601-3609 [PubMed]
  • Aufiero Simona Characterization of the circRNome in the heart: A bioinformatic approach 2020. 159p. ISBN 9789402819205. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Pinto Yigal, Zwinderman A. H.; Co-supervisor: Creemers Esther E. J. M.)
  • Aufiero Simona, Reckman Yolan J., Tijsen Anke J., Pinto Yigal M., Creemers Esther E. circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs BMC bioinformatics 2020;21 (1):164 [PubMed]
  • McNally Elizabeth M., Mann Douglas L., Pinto Yigal, Bhakta Deepak, Tomaselli Gordon, Nazarian Saman, Groh William J., Tamura Takuhisa, Duboc Denis, Itoh Hideki, Hellerstein Leah, Mammen Pradeep P. A. Clinical Care Recommendations for Cardiologists Treating Adults With Myotonic Dystrophy Journal of the American Heart Association 2020;9 (4):e014006 [PubMed]
  • Leerink Jan M., Feijen E. Lieke A. M., van der Pal Helena J. H., Kok Wouter E. M., Mavinkurve-Groothuis Annelies M. C., Kapusta Livia, Pinto Yigal M., Maas Angela H. E. M., Bellersen Louise, Teske Arco J., Ronckers Cécile M., Louwerens Marloes, van Dalen Elvira C., van Dulmen-den Broeder Eline, Batenburg Lilian, van der Heiden-van der Loo Margriet, van den Heuvel-Eibrink Marry M., van Leeuwen Flora E., de Vries Andrica C. H., Weijers Gert, de Korte Chris L., Loonen Jacqueline J., Neggers Sebastian J. C. M. M., Versluys A. B. Birgitta, Tissing Wim J. E., Kremer Leontien C. M. Diagnostic tools for early detection of cardiac dysfunction in childhood cancer survivors: Methodological aspects of the Dutch late effects after childhood cancer (LATER) cardiology study American heart journal 2020;219:89-98 [PubMed]
  • de Groot N. E., van den Hoogenhof M. M. G., Najafi A., van der Made I., van der Velden J., Beqqali A., Pinto Y. M., Creemers E. E. Heterozygous loss of Rbm24 in the adult mouse heart increases sarcomere slack length but does not affect function Scientific reports 2020;10 (1):7687 [PubMed]
  • Akinrinade Oyediran, Heliö Tiina, Lekanne Deprez Ronald H., Jongbloed Jan D. H., Boven Ludolf G., van den Berg Maarten P., Pinto Yigal M., Alastalo Tero-Pekka, Myllykangas Samuel, van Spaendonck-Zwarts Karin, van Tintelen J. Peter, van der Zwaag Paul A., Koskenvuo Juha Publisher Correction: Relevance of Titin Missense and Non-Frameshifting Insertions/Deletions Variants in Dilated Cardiomyopathy (Scientific Reports, (2019), 9, 1, (4093), 10.1038/s41598-019-39911-x) Scientific reports 2020;10 (1) [PubMed]
  • Gommans D. H. Frank, Nas Joris, Pinto-Sietsma Sara-Joan, Koop Yvonne, Konst Regina E., Mensink Frans, Aarts Goaris W. A., Konijnenberg Lara S. F., Cortenbach Kimberley, Verhaert Dominique V. M., Thannhauser Jos, Mol Jan-Quinten, Rooijakkers Maxim J. P., Vos Jacqueline L., van Rumund Anouke, Vart Priya, Hassing Robert-Jan, Cornel Jan-Hein, de Jager C. Peter C., van den Heuvel Michel M., van der Hoeven Hans G., Verbon Annelies, Pinto Yigal M., van Royen Niels, van Kimmenade Roland R. J., de Leeuw Peter W., van Agtmael Michiel A., Bresser Paul, van Gilst Wiek H., Vonk-Noordergraaf Anton, Tijssen Jan G. P. Rationale and design of the PRAETORIAN-COVID trial: A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrome in hospitAlized patieNts with SARS-COV-2 Infection Disease: PRAETORIAN-COVID (NCT04335786) American heart journal 2020;226:60-68 [PubMed]
  • Michaels Alexander, Aurora Lindsey, Peterson Edward, Liu Bin, Pinto Yigal M., Sabbah Hani N., Williams Keoki, Lanfear David E. Risk Prediction in Transition: MAGGIC Score Performance at Discharge and Incremental Utility of Natriuretic Peptides Journal of cardiac failure 2020;26 (1):52-60 [PubMed]
  • Aurora Lindsey, Peterson Edward, Gui Hongsheng, Zeld Nicole, McCord James, Pinto Yigal, Cook Bernard, Sabbah Hani N., Keoki Williams L., Snider James, Lanfear David E. Suppression tumorigenicity 2 (ST2) turbidimetric immunoassay compared to enzyme-linked immunosorbent assay in predicting survival in heart failure patients with reduced ejection fraction Clinica chimica acta; international journal of clinical chemistry 2020;510:767-771 [PubMed]
  • Offringa Annette, Montijn Roy, Singh Sandeep, Paul Martin, Pinto Yigal M., Pinto-Sietsma Sara-Joan The mechanistic overview of SARS-CoV-2 using angiotensin-converting enzyme 2 to enter the cell for replication: possible treatment options related to the renin-angiotensin system European heart journal. Cardiovascular pharmacotherapy 2020;6 (5):317-325 [PubMed]
  • van Hattum J. C., Verwijs S. M., Rienks R., Bijsterveld N. R., de Vries S. T., Pinto Y. M., Wilde A. A. M., Jørstad H. T. The Netherlands Sports Cardiology Map: a step towards sports cardiology network medicine for patient and athlete care Netherlands heart journal 2020 [PubMed]
  • Jansweijer Joeri A. Variable phenotypes in hereditary cardiomyopathies 2020. 162p. ISBN 9789402819809. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Yigal; Co-supervisor: van Spaendonck-Zwarts Karin Y.)
  • Pinto Y. M. Will the new decade bring home remote monitoring of heart failure patients? Netherlands heart journal 2020;28 (1):1-2 [PubMed]

2019

  • Leerink Jan M., Verkleij Simone J., Feijen Elizabeth A. M., Mavinkurve-Groothuis Annelies M. C., Pourier Milanthy S., Ylänen Kaisa, Tissing Wim J. E., Louwerens Marloes, van den Heuvel Marry M., van Dulmen-den Broeder Eline, de Vries Andrica C. H., Ronckers Cecile M., van der Pal Heleen J. H., Kapusta Livia, Loonen Jacqueline, Bellersen Louise, Pinto Yigal M., Kremer Leontien C. M., Kok Wouter E. M. Biomarkers to diagnose ventricular dysfunction in childhood cancer survivors: A systematic review Heart (British Cardiac Society) 2019;105 (3):210-216 [PubMed]
  • Aufiero Simona, Reckman Yolan J., Pinto Yigal M., Creemers Esther E. Circular RNAs open a new chapter in cardiovascular biology Nature reviews. Cardiology 2019;16 (8):503–514 [PubMed]
  • Salah Khibar, Stienen Susan, Moons Andreas H. M., Bakx Adrianus L. M., van Pol Petra E., Kortz R. A. Mikael, Ferreira João Pedro, Marques Irene, Schroeder-Tanka Jutta M., Keijer Jan T., Bayes-Genis Antoni, Pinto Yigal M., Tijssen Jan G., Kok Wouter E. External Validation of the ELAN-HF Score, Predicting 6-Month All-Cause Mortality in Patients Hospitalized for Acute Decompensated Heart Failure Journal of the American Heart Association 2019;8 (14):e010309 [PubMed]
  • Jansweijer Joeri A., van Spaendonck-Zwarts Karin Y., Tanck Michael W. T., Peter van Tintelen J., Christiaans Imke, van der Smagt Jasper, Vermeer Alexa, Bos J. Martijn, Moss Arthur J., Swan Heikki, Priori Sylvia, Rydberg Annika, Tfelt-Hansen Jacob, Ackerman Michael, Olivotto Iacopo, Charron Philippe, Gimeno Juan R., van den Berg Maarten, Wilde Arthur, Pinto Yigal M. Heritability in genetic heart disease: The role of genetic background Open heart 2019;6 (1) [PubMed]
  • Donal Erwan, Delgado Victoria, Bucciarelli-Ducci Chiara, Galli Elena, Haugaa Kristina H., Charron Philippe, Voigt Jens-Uwe, Cardim Nuno, Masci P. G., Galderisi Maurizio, Gaemperli Oliver, Gimelli Alessia, Pinto Yigal M., Lancellotti Patrizio, Habib Gilbert, Elliott Perry, Edvardsen Thor, Cosyns Bernard, Popescu Bogdan A., Gerber Bernhard, Muraru Denisa, Flachskampf Frank, Plein Sven, Neglia Danilo, Cameli Matteo, Weytjens Caroline Multimodality imaging in the diagnosis, risk stratification, and management of patients with dilated cardiomyopathies: an expert consensus document from the European Association of Cardiovascular Imaging European heart journal cardiovascular Imaging 2019;20 (10):1075-1093 [PubMed]
  • Salah Khibar, Stienen Susan, Pinto Yigal M., Eurlings Luc W., Metra Marco, Bayes-Genis Antoni, Verdiani Valerio, Tijssen Jan G. P., Kok Wouter E. Prognosis and NT-proBNP in heart failure patients with preserved versus reduced ejection fraction Heart (British Cardiac Society) 2019;105 (15):1182-1189 [PubMed]
  • Akinrinade Oyediran, Heliö Tiina, Lekanne Deprez Ronald H., Jongbloed Jan D. H., Boven Ludolf G., van den Berg Maarten P., Pinto Yigal M., Alastalo Tero-Pekka, Myllykangas Samuel, Spaendonck-Zwarts Karin van, Tintelen J. Peter van, van der Zwaag Paul A., Koskenvuo Juha Relevance of Titin Missense and Non-Frameshifting Insertions/Deletions Variants in Dilated Cardiomyopathy Scientific reports 2019;9 (1) [PubMed]
  • Pinto Y. Seeing the disease before it has manifested itself Netherlands heart journal 2019;27 (3):115-116 [PubMed]
  • Raso Andrea, Dirkx Ellen, Philippen Leonne E., Fernandez-Celis Amaya, de Majo Federica, Sampaio-Pinto Vasco, Sansonetti Marida, Juni Rio, el Azzouzi Hamid, Calore Martina, Bitsch Nicole, Olieslagers Servé, Oerlemans Martinus I. F. J., Huibers Manon M., de Weger Roel A., Reckman Yolan J., Pinto Yigal M., Zentilin Lorena, Zacchigna Serena, Giacca Mauro, da Costa Martins Paula A., López-Andrés Natalia, de Windt Leon J. Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure Molecular therapy 2019;27 (3):584-599 [PubMed]

2018

  • van den Hoogenhof Maarten M. G., van der Made Ingeborg, de Groot Nina E., Damanafshan Amin, van Amersfoorth Shirley C. M., Zentilin Lorena, Giacca Mauro, Pinto Yigal M., Creemers Esther E. AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart Scientific reports 2018;8 (1) [PubMed]
  • van Tintelen J Peter, Pinto Yigal M Additional Genetic Variants in Inherited Dilated Cardiomyopathy: Just Another Brick in the Wall? Circulation. Genomic and precision medicine 2018;11 (7):e002249 [PubMed]
  • Aufiero Simona, van den Hoogenhof Maarten M. G., Reckman Yolan J., Beqqali Abdelaziz, van der Made Ingeborg, Kluin Jolanda, Khan Mohsin A. F., Pinto Yigal M., Creemers Esther E. Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons RNA (New York, N.Y.) 2018;24 (6):815-827 [PubMed]
  • Pinto Yigal M., Reckman Yolan J. Formins Emerge as a Cause of Hypertrophic Cardiomyopathy: New Genes for Thick Hearts ∗ Journal of the American College of Cardiology 2018;72 (20):2468-2470 [PubMed]
  • Salah Khibar NT-proBNP as a risk stratification tool for the management of acute decompensated heart failure 2018. ISBN 9789463611695. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisors: Kok W. E. M., Tijssen J. G. P.)
  • Stienen Susan NT-proBNP-guided therapy in acute decompensated heart failure 2018. ISBN 9789463610551. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Kok W. E. M.)
  • Stienen Susan, Salah Khibar, Moons Arno H., Bakx Adrianus L., van Pol Petra, Kortz Mikael, Ferreira João Pedro, Marques Irene, Schroeder-Tanka Jutta M., Keijer Jan T., Bayés-Genis Antoni, Tijssen Jan G. P., Pinto Yigal M., Kok Wouter E. NT-proBNP-Guided Therapy in Acute Decompensated Heart Failure: The PRIMA II Randomized Controlled Trial Circulation 2018;137 (16):1671–1683 [PubMed]
  • Bayés-Genis Antoni, Lanfear David E., de Ronde Maurice W. J., Lupón Josep, Leenders Joost J., Liu Zhen, Zuithoff Nicolaas P. A., Eijkemans Marinus J. C., Zamora Elisabet, de Antonio Marta, Zwinderman Aeilko H., Pinto-Sietsma Sara-Joan, Pinto Yigal M. Prognostic value of circulating microRNAs on heart failure-related morbidity and mortality in two large diverse cohorts of general heart failure patients European journal of heart failure 2018;20 (1):67-75 [PubMed]
  • Luzum Jasmine A., Peterson Edward, Li Jia, She Ruicong, Gui Hongsheng, Liu Bin, Spertus John A., Pinto Yigal M., Keoki Williams L., Sabbah Hani N., Lanfear David E. Race and beta-blocker survival benefit in patients with heart failure: An investigation of self-reported race and proportion of African Genetic Ancestry Journal of the American Heart Association 2018;7 (10) [PubMed]
  • van den Hoogenhof Maarten M. G., Beqqali Abdelaziz, Amin Ahmad S., van der Made Ingeborg, Aufiero Simona, Khan Mohsin A. F., Schumacher Cees A., Jansweijer Joeri A., van Spaendonck-Zwarts Karin Y., Remme Carol Ann, Backs Johannes, Verkerk Arie O., Baartscheer Antonius, Pinto Yigal M., Creemers Esther E. RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling Circulation 2018;138 (13):1330-1342 [PubMed]
  • Pinto Y. Reply to the letter from Damman et al.: Heart transplantation in the Netherlands: a national achievement Netherlands heart journal 2018;26 (4):225 [PubMed]
  • van den Hoogenhof Maarten M. G. RNA splicing in the heart: Changing parts and performance 2018. ISBN 9789402809534. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)
  • van Boven Nick, Kardys Isabella, van Vark Laura C., Akkerhuis K. Martijn, de Ronde Maurice W. J., Khan Mohsin A. F., Merkus Daphne, Liu Zhen, Voors Adriaan A., Asselbergs Folkert W., van den Bos Ewout-Jan, Boersma Eric, Hillege Hans, Duncker Dirk J., Pinto Yigal M., Postmus Douwe Serially measured circulating microRNAs and adverse clinical outcomes in patients with acute heart failure European journal of heart failure 2018;20 (1):89-96 [PubMed]
  • Al-Saaidi Rasha A., Rasmussen Torsten B., Birkler Rune I. D., Palmfeldt Johan, Beqqali Abdelaziz, Pinto Yigal M., Nissen Peter H., Baandrup Ulrik, Mølgaard Henning, Hey Thomas M., Eiskjær Hans, Bross Peter, Mogensen Jens The clinical outcome of LMNA missense mutations can be associated with the amount of mutated protein in the nuclear envelope European journal of heart failure 2018;20 (10):1404-1412 [PubMed]
  • Hoorntje Edgar T., van Spaendonck-Zwarts Karin Y., te Rijdt Wouter P., Boven Ludolf, Vink Aryan, van der Smagt Jasper J., Asselbergs Folkert W., van Wijngaarden Jan, Hennekam Eric A., Pinto Yigal M., Lekanne Deprez Ronald H., Barge-Schaapveld Daniela Q. C. M., Bootsma Marianne, Regieli Jakub, Hoedemaekers Yvonne M., Jongbloed Jan D. H., van den Berg Maarten P., van Tintelen J. Peter The first titin (c.59926 + 1G > A) founder mutation associated with dilated cardiomyopathy European journal of heart failure 2018;20 (4):803-806 [PubMed]
  • Damanafshan Amin, Elzenaar Ies, Samson-Couterie Benoit, van der Made Ingeborg, Bourajjaj Meriem, van den Hoogenhof Maarten M., van Veen Henk A., Picavet Daisy I., Beqqali Abdelaziz, Ehler Elisabeth, de Windt Leon J., Pinto Yigal M., van Oort Ralph J. The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy Cardiovascular research 2018;114 (11):1474-1486 [PubMed]
  • Leerink J. M., Pinto Y. M. Towards evidence-based management of patients treated with cardiotoxic chemotherapy: A collaborative effort of cardiologists and oncologists Netherlands heart journal 2018;26 (11):519-520 [PubMed]

2017

  • Nolte Ilja M., Jansweijer Joeri A., Riese Hariette, Asselbergs Folkert W., van der Harst Pim, Spector Timothy D., Pinto Yigal M., Snieder Harold, Jamshidi Yalda A Comparison of Heritability Estimates by Classical Twin Modeling and Based on Genome-Wide Genetic Relatedness for Cardiac Conduction Traits Twin research and human genetics 2017;20 (6):489-498 [PubMed]
  • Heggermont Ward A., Papageorgiou Anna-Pia, Quaegebeur Annelies, Deckx Sophie, Carai Paolo, Verhesen Wouter, Eelen Guy, Schoors Sandra, van Leeuwen Rick, Alekseev Sergey, Elzenaar Ies, Vinckier Stefan, Pokreisz Peter, Walravens Ann-Sophie, Gijsbers Rik, van den Haute Chris, Nickel Alexander, Schroen Blanche, van Bilsen Marc, Janssens Stefan, Maack Christoph, Pinto Yigal, Carmeliet Peter, Heymans Stephane Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction Circulation 2017;136 (8):747-761 [PubMed]
  • Bollen Ilse A. E., Ehler Elisabeth, Fleischanderl Karin, Bouwman Floor, Kempers Lanette, Ricke-Hoch Melanie, Hilfiker-Kleiner Denise, dos Remedios Cristobal G., Krüger Martina, Vink Aryan, Asselbergs Folkert W., van Spaendonck-Zwarts Karin Y., Pinto Yigal M., Kuster Diederik W. D., van der Velden Jolanda Myofilament Remodeling and Function Is More Impaired in Peripartum Cardiomyopathy Compared with Dilated Cardiomyopathy and Ischemic Heart Disease American journal of pathology 2017;187 (12):2645-2658 [PubMed]
  • Heinig Matthias, Adriaens Michiel E., Schafer Sebastian, van Deutekom Hanneke W. M., Lodder Elisabeth M., Ware James S., Schneider Valentin, Felkin Leanne E., Creemers Esther E., Meder Benjamin, Katus Hugo A., Rühle Frank, Stoll Monika, Cambien François, Villard Eric, Charron Philippe, Varro Andras, Bishopric Nanette H., George Alfred L., Dos Remedios Cristobal, Moreno-Moral Aida, Pesce Francesco, Bauerfeind Anja, Rüschendorf Franz, Rintisch Carola, Petretto Enrico, Barton Paul J., Cook Stuart A., Pinto Yigal M., Bezzina Connie R., Hubner Norbert Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy Genome biology 2017;18 (1) [PubMed]
  • de Ronde Maurice W. J., Ruijter Jan M., Lanfear David, Bayes-Genis Antoni, Kok Maayke G. M., Creemers Esther E., Pinto Yigal M., Pinto-Sietsma Sara-Joan Practical data handling pipeline improves performance of qPCR-based circulating miRNA measurements RNA (New York, N.Y.) 2017;23 (5):811-821 [PubMed]
  • van Vark Laura C., Lesman-Leegte Ivonne, Baart Sara J., Postmus Douwe, Pinto Yigal M., de Boer Rudolf A., Asselbergs Folkert W., Wajon Elly M. C. J., Orsel Joke G., Boersma Eric, Hillege Hans L., Akkerhuis K. Martijn, Nagelsmit Michiel J., Brunner-La Rocca Hans-Peter, Linssen Gerard C. M., Terpstra Willem F., Liem Anho H., Wardeh Alexander J., van Miltenburg Addy J. M., van den Bos Ewout J., de Ridder Stijn P. J. Prognostic Value of Serial Galectin-3 Measurements in Patients With Acute Heart Failure Journal of the American Heart Association 2017;6 (12) [PubMed]
  • van Vark Laura C., Lesman-Leegte Ivonne, Baart Sara J., Postmus Douwe, Pinto Yigal M., Orsel Joke G., Westenbrink B. Daan, Brunner-la Rocca Hans P., van Miltenburg Addy J. M., Boersma Eric, Hillege Hans L., Akkerhuis K. Martijn Prognostic Value of Serial ST2 Measurements in Patients With Acute Heart Failure Journal of the American College of Cardiology 2017;70 (19):2378-2388 [PubMed]
  • van Boven Nick, Akkerhuis K. Martijn, Anroedh Sharda S., Rizopoulos Dimitris, Pinto Yigal, Battes Linda C., Hillege Hans L., Caliskan Kadir C., Germans Tjeerd, Manintveld Olivier C., Cornel Jan-Hein, Constantinescu Alina A., Boersma Eric, Umans Victor A., Kardys Isabella Serially measured circulating miR-22-3p is a biomarker for adverse clinical outcome in patients with chronic heart failure: The Bio-SHiFT study International journal of cardiology 2017;235:124-132 [PubMed]
  • Lanfear David E., Gibbs Joseph J., Li Jia, She Ruicong, Petucci Christopher, Culver Jeffrey A., Tang W. H. Wilson, Pinto Yigal M., Williams L. Keoki, Sabbah Hani N., Gardell Stephen J. Targeted Metabolomic Profiling of Plasma and Survival in Heart Failure Patients JACC. Heart failure 2017;5 (11):823-832 [PubMed]
  • Tijsen A. J., Pinto Y. M., Creemers E. E. The Clinical Potential of Heart Failure-Related miRNAsin: Translating MicroRNAs to the Clinic. Elsevier Inc.; 2017. p. 283-328, ISBN 9780128005538
  • van den Hoogenhof Maarten M. G., van der Made Ingeborg, Beqqali Abdelaziz, de Groot Nina E., Damanafshan Amin, van Oort Ralph J., Pinto Yigal M., Creemers Esther E. The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice PLoS ONE 2017;12 (8) [PubMed]
  • Pinto Y. M. Three decades of heart transplantation in the Netherlands Netherlands heart journal 2017;25 (9):469-470 [PubMed]
  • Kluin Jolanda, Wilde Arthur A. M., Pinto Yigal, van Herwerden Lex A. To Add or Not to Add Mitral Valve Surgery to Septal Myectomy in HOCM Patients Journal of the American College of Cardiology 2017;69 (17):2250 [PubMed]
  • Jansweijer Joeri A., Nieuwhof Karin, Russo Francesco, Hoorntje Edgar T., Jongbloed Jan D. H., Lekanne Deprez Ronald H., Postma Alex V., Bronk Marieke, van Rijsingen Ingrid A. W., de Haij Simone, Biagini Elena, van Haelst Paul L., van Wijngaarden Jan, van den Berg Maarten P., Wilde Arthur A. M., Mannens Marcel M. A. M., de Boer Rudolf A., van Spaendonck-Zwarts Karin Y., van Tintelen J. Peter, Pinto Yigal M. Truncating titin mutations are associated with a mild and treatable form of dilated cardiomyopathy European journal of heart failure 2017;19 (4):512-521 [PubMed]

2016

  • van der Harst Pim, van Setten Jessica, Verweij Niek, Vogler Georg, Franke Lude, Maurano Matthew T., Wang Xinchen, Mateo Leach Irene, Eijgelsheim Mark, Sotoodehnia Nona, Hayward Caroline, Sorice Rossella, Meirelles Osorio, Lyytikäinen Leo-Pekka, Polašek Ozren, Tanaka Toshiko, Arking Dan E., Ulivi Sheila, Trompet Stella, Müller-Nurasyid Martina, Smith Albert V., Dörr Marcus, Kerr Kathleen F., Magnani Jared W., del Greco M Fabiola, Zhang Weihua, Nolte Ilja M., Silva Claudia T., Padmanabhan Sandosh, Tragante Vinicius, Esko Tõnu, Abecasis Gonçalo R., Adriaens Michiel E., Andersen Karl, Barnett Phil, Bis Joshua C., Bodmer Rolf, Buckley Brendan M., Campbell Harry, Cannon Megan V., Chakravarti Aravinda, Chen Lin Y., Delitala Alessandro, Devereux Richard B., Doevendans Pieter A., Dominiczak Anna F., Ferrucci Luigi, Ford Ian, Gieger Christian, Harris Tamara B., Haugen Eric, Heinig Matthias, Hernandez Dena G., Hillege Hans L., Hirschhorn Joel N., Hofman Albert, Hubner Norbert, Hwang Shih-Jen, Iorio Annamaria, Kähönen Mika, Kellis Manolis, Kolcic Ivana, Kooner Ishminder K., Kooner Jaspal S., Kors Jan A., Lakatta Edward G., Lage Kasper, Launer Lenore J., Levy Daniel, Lundby Alicia, Macfarlane Peter W., May Dalit, Meitinger Thomas, Metspalu Andres, Nappo Stefania, Naitza Silvia, Neph Shane, Nord Alex S., Nutile Teresa, Okin Peter M., Olsen Jesper V., Oostra Ben A., Penninger Josef M., Pennacchio Len A., Pers Tune H., Perz Siegfried, Peters Annette, Pinto Yigal M., Pfeufer Arne, Pilia Maria Grazia, Pramstaller Peter P., Prins Bram P., Raitakari Olli T., Raychaudhuri Soumya, Rice Ken M., Rossin Elizabeth J., Rotter Jerome I., Schafer Sebastian, Schlessinger David, Schmidt Carsten O., Sehmi Jobanpreet, Silljé Herman H. W., Sinagra Gianfranco, Sinner Moritz F., Slowikowski Kamil, Soliman Elsayed Z., Spector Timothy D., Spiering Wilko, Stamatoyannopoulos John A., Stolk Ronald P., Strauch Konstantin, Tan Sian-Tsung, Tarasov Kirill V., Trinh Bosco, Uitterlinden Andre G., van den Boogaard Malou, van Duijn Cornelia M., van Gilst Wiek H., Viikari Jorma S., Visscher Peter M., Vitart Veronique, Völker Uwe, Waldenberger Melanie, Weichenberger Christian X., Westra Harm-Jan, Wijmenga Cisca, Wolffenbuttel Bruce H., Yang Jian, Bezzina Connie R., Munroe Patricia B., Snieder Harold, Wright Alan F., Rudan Igor, Boyer Laurie A., Asselbergs Folkert W., van Veldhuisen Dirk J., Stricker Bruno H., Psaty Bruce M., Ciullo Marina, Sanna Serena, Lehtimäki Terho, Wilson James F., Bandinelli Stefania, Alonso Alvaro, Gasparini Paolo, Jukema J. Wouter, Kääb Stefan, Gudnason Vilmundur, Felix Stephan B., Heckbert Susan R., de Boer Rudolf A., Newton-Cheh Christopher, Hicks Andrew A., Chambers John C., Jamshidi Yalda, Visel Axel, Christoffels Vincent M., Isaacs Aaron, Samani Nilesh J., de Bakker Paul I. W. 52 Genetic Loci Influencing Myocardial Mass Journal of the American College of Cardiology 2016;68 (13):1435-1448 [PubMed]
  • Beqqali Abdelaziz, Bollen Ilse A. E., Rasmussen Torsten B., van den Hoogenhof Maarten M., van Deutekom Hanneke W. M., Schafer Sebastian, Haas Jan, Meder Benjamin, Sørensen Keld E., van Oort Ralph J., Mogensen Jens, Hubner Norbert, Creemers Esther E., van der Velden Jolanda, Pinto Yigal M. A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism Cardiovascular research 2016;112 (1):452-463 [PubMed]
  • West James A., Beqqali Abdelaziz, Ament Zsuzsanna, Elliott Perry, Pinto Yigal M., Arbustini Eloisa, Griffin Julian L. A targeted metabolomics assay for cardiac metabolism and demonstration using a mouse model of dilated cardiomyopathy Metabolomics 2016;12 (3):59 [PubMed]
  • de Ronde Maurice W. J., Pinto Yigal M., Pinto-Sietsma Sara-Joan Circulating microRNA biomarkers for cardiovascular risk prediction: are we approaching clinical application? Annals of translational medicine 2016;4 (24):490 [PubMed]
  • Elliott Perry, Charron Philippe, Blanes Juan Ramon Gimeno, Tavazzi Luigi, Tendera Michal, Konté Marème, Laroche Cécile, Maggioni Aldo P., Anastasakis Aris, Arbustini Eloisa, Asselbergs Folkert W., Axelsson Anna, Brito Dulce, Caforio Alida L.P., Carr-White Gerald, Czekaj Agata, Damy Thibaud, Devoto Emmanuela, Favalli Valentina, Findlay Iain, Garcia-Pavia Pablo, Hagège Albert, Heliö Tiina, Iliceto Sabino, Isnard Richard, Jansweijer Joeri A., Limongelli Giuseppe, Linhart Ales, Cuenca David López, Mansencal Nicolas, McKeown Pascal, Mogensen Jens, Mohiddin Saidi A., Monserrat Lorenzo, Olivotto Iacopo, Rapezzi Claudio, Rigopoulos A. G., Rosmini Stefania, Pfeiffer Barbara, Wicks Eleanor, Podzimkova J., Kuchynka P., Palecek T., Bundgaard H., Thune J. J., Kumme A., Due Vestergaard L., Wilde A.A.M., Pinto Y., Van Der Heijden J. F. European cardiomyopathy pilot registry: EURObservational research programme of the European society of cardiology European heart journal 2016;37 (2):164-173 [PubMed]
  • Nicod Jérôme, Davies Robert W., Cai Na, Hassett Carl, Goodstadt Leo, Cosgrove Cormac, Yee Benjamin K., Lionikaite Vikte, McIntyre Rebecca E., Remme Carol Ann, Lodder Elisabeth M., Gregory Jennifer S., Hough Tertius, Joynson Russell, Phelps Hayley, Nell Barbara, Rowe Clare, Wood Joe, Walling Alison, Bopp Nasrin, Bhomra Amarjit, Hernandez-Pliego Polinka, Callebert Jacques, Aspden Richard M., Talbot Nick P., Robbins Peter A., Harrison Mark, Fray Martin, Launay Jean-Marie, Pinto Yigal M., Blizard David A., Bezzina Connie R., Adams David J., Franken Paul, Weaver Tom, Wells Sara, Brown Steve D. M., Potter Paul K., Klenerman Paul, Lionikas Arimantas, Mott Richard, Flint Jonathan Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing Nature genetics 2016;48 (8):912-918 [PubMed]
  • Creemers Esther E., Bawazeer Amira, Ugalde Alejandro P., van Deutekom Hanneke W. M., van der Made Ingeborg, de Groot Nina E., Adriaens Michiel E., Cook Stuart A., Bezzina Connie R., Hubner Norbert, van der Velden Jolanda, Elkon Ran, Agami Reuven, Pinto Yigal M. Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart Circulation research 2016;118 (3):433-438 [PubMed]
  • Amin Ahmad S., Pinto Yigal M., Ackerman Michael J., Wilde Arthur A. M. Letter by Amin et al Regarding Article, "Genetic Modifiers for the Long-QT Syndrome: How Important Is the Role of Variants in the 3 ' Untranslated Region of KCNQ1?" Circulation. Cardiovascular genetics 2016;9 (6):580 [PubMed]
  • Vegter Eline L., van der Meer Peter, de Windt Leon J., Pinto Yigal M., Voors Adriaan A. MicroRNAs in heart failure: from biomarker to target for therapy European journal of heart failure 2016;18 (5):457-468 [PubMed]
  • Bruno Noemi, ter Maaten Jozine M., Ovchinnikova Ekaterina S., Vegter Eline L., Valente Mattia A. E., van der Meer Peter, de Boer Rudolf A., van der Harst Pim, Schmitter Daniela, Metra Marco, O'Connor Christopher M., Ponikowski Piotr, Teerlink John R., Cotter Gad, Davison Beth, Cleland John G., Givertz Michael M., Bloomfield Daniel M., Dittrich Howard C., Pinto Yigal M., van Veldhuisen Dirk J., Hillege Hans L., Berezikov Eugene, Voors Adriaan A. MicroRNAs relate to early worsening of renal function in patients with acute heart failure International journal of cardiology 2016;203:564-569 [PubMed]
  • Pinto Yigal M., Elliott Perry M., Arbustini Eloisa, Adler Yehuda, Anastasakis Aris, Böhm Michael, Duboc Denis, Gimeno Juan, de Groote Pascal, Imazio Massimo, Heymans Stephane, Klingel Karin, Komajda Michel, Limongelli Giuseppe, Linhart Ales, Mogensen Jens, Moon James, Pieper Petronella G., Seferovic Petar M., Schueler Stephan, Zamorano Jose L., Caforio Alida L. P., Charron Philippe Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases European heart journal 2016;37 (23):1850-1858 [PubMed]
  • Khan Mohsin A. F., Reckman Yolan J., Aufiero Simona, van den Hoogenhof Maarten M. G., van der Made Ingeborg, Beqqali Abdelaziz, Koolbergen Dave R., Rasmussen Torsten B., van der Velden Jolanda, Creemers Esther E., Pinto Yigal M. RBM20 Regulates Circular RNA Production From the Titin Gene Circulation research 2016;119 (9):996-1003 [PubMed]
  • Salah Khibar, Kok Wouter E., Pinto Yigal M. Reply: Worsening Renal Function in Acute Decompensated Heart Failure: The Puzzle is Still Incomplete JACC. Heart failure 2016;4 (3):233-234 [PubMed]
  • Hibender Stijntje, Franken Romy, van Roomen Cindy, ter Braake Anique, van der Made Ingeborg, Schermer Edith E., Gunst Quinn, van den Hoff Maurice J., Lutgens Esther, Pinto Yigal M., Groenink Maarten, Zwinderman Aeilko H., Mulder Barbara J. M., de Vries Carlie J. M., de Waard Vivian Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model Arteriosclerosis, thrombosis, and vascular biology 2016;36 (8):1618-1626 [PubMed]
  • van den Hoogenhof Maarten M. G., Pinto Yigal M., Creemers Esther E. RNA Splicing: Regulation and Dysregulation in the Heart Circulation research 2016;118 (3):454-468 [PubMed]
  • Ovchinnikova Ekaterina S., Schmitter Daniela, Vegter Eline L., ter Maaten Jozine M., Valente Mattia A. E., Liu Licette C. Y., van der Harst Pim, Pinto Yigal M., de Boer Rudolf A., Meyer Sven, Teerlink John R., O'Connor Christopher M., Metra Marco, Davison Beth A., Bloomfield Daniel M., Cotter Gadi, Cleland John G., Mebazaa Alexandre, Laribi Said, Givertz Michael M., Ponikowski Piotr, van der Meer Peter, van Veldhuisen Dirk J., Voors Adriaan A., Berezikov Eugene Signature of circulating microRNAs in patients with acute heart failure European journal of heart failure 2016;18 (4):414-423 [PubMed]
  • Stienen Susan, Salah Khibar, Eurlings Luc W., Bettencourt Paulo, Pimenta Joana M., Metra Marco, Bayes-Genis Antoni, Verdiani Valerio, Bettari Luca, Lazzarini Valentina, Tijssen Jan P., Pinto Yigal M., Kok Wouter E. Targeting N-Terminal Pro-Brain Natriuretic Peptide in Older Versus Younger Acute Decompensated Heart Failure Patients JACC. Heart failure 2016;4 (9):736-745 [PubMed]

2015

  • Haas Jan, Frese Karen S., Peil Barbara, Kloos Wanda, Keller Andreas, Nietsch Rouven, Feng Zhu, Müller Sabine, Kayvanpour Elham, Vogel Britta, Sedaghat-Hamedani Farbod, Lim Wei-Keat, Zhao Xiaohong, Fradkin Dmitriy, Köhler Doreen, Fischer Simon, Franke Jennifer, Marquart Sabine, Barb Ioana, Li Daniel Tian, Amr Ali, Ehlermann Philipp, Mereles Derliz, Weis Tanja, Hassel Sarah, Kremer Andreas, King Vanessa, Wirsz Emil, Isnard Richard, Komajda Michel, Serio Alessandra, Grasso Maurizia, Syrris Petros, Wicks Eleanor, Plagnol Vincent, Lopes Luis, Gadgaard Tenna, Eiskjær Hans, Jørgensen Mads, Garcia-Giustiniani Diego, Ortiz-Genga Martin, Crespo-Leiro Maria G., Deprez Rondal H. Lekanne Dit, Christiaans Imke, van Rijsingen Ingrid A., Wilde Arthur A., Waldenstrom Anders, Bolognesi Martino, Bellazzi Riccardo, Mörner Stellan, Bermejo Justo Lorenzo, Monserrat Lorenzo, Villard Eric, Mogensen Jens, Pinto Yigal M., Charron Philippe, Elliott Perry, Arbustini Eloisa, Katus Hugo A., Meder Benjamin Atlas of the clinical genetics of human dilated cardiomyopathy European heart journal 2015;36 (18):1123-135a [PubMed]
  • Stienen Susan, Salah Khibar, Eurlings Luc W. M., Bettencourt Paulo, Pimenta Joana M., Metra Marco, Bayes-Genis Antoni, Verdiani Valerio, Bettari Luca, Lazzarini Valentina, Tijssen Jan P., Pinto Yigal M., Kok Wouter E. M. Challenging the two concepts in determining the appropriate pre-discharge N-terminal pro-brain natriuretic peptide treatment target in acute decompensated heart failure patients: absolute or relative discharge levels? European journal of heart failure 2015;17 (9):936-944 [PubMed]
  • Salah Khibar, Kok Wouter E., Eurlings Luc W., Bettencourt Paulo, Pimenta Joana M., Metra Marco, Verdiani Valerio, Tijssen Jan G., Pinto Yigal M. Competing Risk of Cardiac Status and Renal Function During Hospitalization for Acute Decompensated Heart Failure JACC. Heart failure 2015;3 (10):751-761 [PubMed]
  • Olivotto Iacopo, d'Amati Giulia, Basso Cristina, van Rossum Albert, Patten Monica, Emdin Michele, Pinto Yigal, Tomberli Benedetta, Camici Paolo G., Michels Michelle Defining phenotypes and disease progression in sarcomeric cardiomyopathies: contemporary role of clinical investigations Cardiovascular research 2015;105 (4):409-423 [PubMed]
  • Ho Carolyn Y., Charron Philippe, Richard Pascale, Girolami Francesca, van Spaendonck-Zwarts Karin Y., Pinto Yigal Genetic advances in sarcomeric cardiomyopathies: state of the art Cardiovascular research 2015;105 (4):397-408 [PubMed]
  • Stienen Susan, Salah Khibar, Dickhoff Cathelijne, Carubelli Valentina, Metra Marco, Magrini Laura, Di Somma Salvatore, Tijssen Jan P., Pinto Yigal M., Kok Wouter E. N-Terminal Pro-B-Type Natriuretic Peptide (NT-proBNP) Measurements Until a 30% Reduction Is Attained During Acute Decompensated Heart Failure Admissions and Comparison With Discharge NT-proBNP Levels: Implications for In-Hospital Guidance of Treatment Journal of cardiac failure 2015;21 (11):930-934 [PubMed]
  • Wijnen Winandus Johannes Regulation of cardiac form and function: small RNAs and large hearts 2015. 138p. ISBN 9789462596672. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)
  • Salah Khibar, Pinto Yigal M., Eurlings Luc W., Metra Marco, Stienen Susan, Lombardi Carlo, Tijssen Jan G., Kok Wouter E. Serum potassium decline during hospitalization for acute decompensated heart failure is a predictor of 6-month mortality, independent of N-terminal pro-B-type natriuretic peptide levels: An individual patient data analysis American heart journal 2015;170 (3):531-42.e1 [PubMed]
  • Mogensen Jens, van Tintelen J. Peter, Fokstuen Siv, Elliott Perry, van Langen Irene M., Meder Benjamin, Richard Pascale, Syrris Petros, Caforio Alida L. P., Adler Yehuda, Anastasakis Aris, Gimeno Juan R., Klingel Karin, Linhart Ales, Imazio Massimo, Pinto Yigal, Newbery Ruth, Schmidtke Joerg, Charron Philippe The current role of next-generation DNA sequencing in routine care of patients with hereditary cardiovascular conditions: a viewpoint paper of the European Society of Cardiology working group on myocardial and pericardial diseases and members of the European Society of Human Genetics European heart journal 2015;36 (22):1367-1370 [PubMed]
  • Brunner-La Rocca Hans-Peter, Eurlings Luc, Richards A. Mark, Januzzi James L., Pfisterer Matthias E., Dahlström Ulf, Pinto Yigal M., Karlström Patric, Erntell Hans, Berger Rudolf, Persson Hans, O'Connor Christopher M., Moertl Deddo, Gaggin Hanna K., Frampton Christopher M., Nicholls M. Gary, Troughton Richard W. Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials European journal of heart failure 2015;17 (12):1252-1261 [PubMed]

2014

  • Salah Khibar, Kok Wouter E., Eurlings Luc W., Bettencourt Paulo, Pimenta Joana M., Metra Marco, Bayes-Genis Antoni, Verdiani Valerio, Bettari Luca, Lazzarini Valentina, Damman Peter, Tijssen Jan G., Pinto Yigal M. A novel discharge risk model for patients hospitalised for acute decompensated heart failure incorporating N-terminal pro-B-type natriuretic peptide levels: a European coLlaboration on Acute decompeNsated Heart Failure: ELAN-HF Score Heart (British Cardiac Society) 2014;100 (2):115-125 [PubMed]
  • Wijnen Wino J., van der Made Ingeborg, van den Oever Stephanie, Hiller Monika, de Boer Bouke A., Picavet Daisy I., Chatzispyrou Iliana A., Houtkooper Riekelt H., Tijsen Anke J., Hagoort Jaco, van Veen Henk, Everts Vincent, Ruijter Jan M., Pinto Yigal M., Creemers Esther E. Cardiomyocyte-specific miRNA-30c over-expression causes dilated cardiomyopathy PLoS ONE 2014;9 (5):e96290 [PubMed]
  • Troughton Richard W., Frampton Christopher M., Brunner-La Rocca Hans-Peter, Pfisterer Matthias, Eurlings Luc W. M., Erntell Hans, Persson Hans, O'Connor Christopher M., Moertl Deddo, Karlström Patric, Dahlström Ulf, Gaggin Hanna K., Januzzi James L., Berger Rudolf, Richards A. Mark, Pinto Yigal M., Nicholls M. Gary Effect of B-type natriuretic peptide-guided treatment of chronic heart failure on total mortality and hospitalization: an individual patient meta-analysis European heart journal 2014;35 (23):1559-1567 [PubMed]
  • Milano Annalisa, Vermeer Alexa M. C., Lodder Elisabeth M., Barc Julien, Verkerk Arie O., Postma Alex V., van der Bilt Ivo A. C., Baars Marieke J. H., van Haelst Paul L., Caliskan Kadir, Hoedemaekers Yvonne M., Le Scouarnec Solena, Redon Richard, Pinto Yigal M., Christiaans Imke, Wilde Arthur A., Bezzina Connie R. HCN4 mutations in multiple families with bradycardia and left ventricular noncompaction cardiomyopathy Journal of the American College of Cardiology 2014;64 (8):745-756 [PubMed]
  • van Rijsingen Ingrid A. W., van der Zwaag Paul A., Groeneweg Judith A., Nannenberg Eline A., Jongbloed Jan D. H., Zwinderman Aeilko H., Pinto Yigal M., Dit Deprez Ronald H. Lekanne, Post Jan G., Tan Hanno L., de Boer Rudolf A., Hauer Richard N. W., Christiaans Imke, van den Berg Maarten P., van Tintelen J. Peter, Wilde Arthur A. M. Outcome in phospholamban R14del carriers: results of a large multicentre cohort study Circulation. Cardiovascular genetics 2014;7 (4):455-465 [PubMed]
  • Stienen Susan, Salah Khibar, Moons Andreas H. M., Bakx Adrianus L. M., van Pol Petra E., Schroeder-Tanka Jutta M., Voogel Albertus J., Keijer Jan T., Kortz R. A. Mikael, Dickhoff Cathelijne, Meregalli Paola G., Tijssen Jan G., Pinto Yigal M., Kok Wouter E. Rationale and design of PRIMA II: A multicenter, randomized clinical trial to study the impact of in-hospital guidance for acute decompensated heart failure treatment by a predefined NT-PRoBNP target on the reduction of readmIssion and Mortality rAtes American heart journal 2014;168 (1):30-36 [PubMed]
  • Eurlings Luc W., Sanders-van Wijk Sandra, van Kraaij Dave J. W., van Kimmenade Roland, Meeder Joan G., Kamp Otto, van Dieijen-Visser Marja P., Tijssen Jan G. P., Brunner-La Rocca Hans-Peter, Pinto Yigal M. Risk stratification with the use of serial N-terminal pro-B-type natriuretic peptide measurements during admission and early after discharge in heart failure patients: post hoc analysis of the PRIMA study Journal of cardiac failure 2014;20 (12):881-890 [PubMed]
  • Tijsen Anke J., van der Made Ingeborg, van den Hoogenhof Maarten M., Wijnen Wino J., van Deel Elza D., de Groot Nina E., Alekseev Sergey, Fluiter Kees, Schroen Blanche, Goumans Marie-José, van der Velden Jolanda, Duncker Dirk J., Pinto Yigal M., Creemers Esther E. The microRNA-15 family inhibits the TGFβ-pathway in the heart Cardiovascular research 2014;104 (1):61-71 [PubMed]
  • Ristić Arsen D., Imazio Massimo, Adler Yehuda, Anastasakis Aristides, Badano Luigi P., Brucato Antonio, Caforio Alida L. P., Dubourg Olivier, Elliott Perry, Gimeno Juan, Helio Tiina, Klingel Karin, Linhart Aleš, Maisch Bernhard, Mayosi Bongani, Mogensen Jens, Pinto Yigal, Seggewiss Hubert, Seferović Petar M., Tavazzi Luigi, Tomkowski Witold, Charron Philippe Triage strategy for urgent management of cardiac tamponade: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases European heart journal 2014;35 (34):2279-2284 [PubMed]

2013

  • Caforio Alida L. P., Pankuweit Sabine, Arbustini Eloisa, Basso Cristina, Gimeno-Blanes Juan, Felix Stephan B., Fu Michael, Heliö Tiina, Heymans Stephane, Jahns Roland, Klingel Karin, Linhart Ales, Maisch Bernhard, McKenna William, Mogensen Jens, Pinto Yigal M., Ristic Arsen, Schultheiss Heinz-Peter, Seggewiss Hubert, Tavazzi Luigi, Thiene Gaetano, Yilmaz Ali, Charron Philippe, Elliott Perry M. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases European heart journal 2013;34 (33):2636-48, 2648a-2648d [PubMed]
  • Rapezzi Claudio, Arbustini Eloisa, Caforio Alida L. P., Charron Philippe, Gimeno-Blanes Juan, Heliö Tiina, Linhart Ales, Mogensen Jens, Pinto Yigal, Ristic Arsen, Seggewiss Hubert, Sinagra Gianfranco, Tavazzi Luigi, Elliott Perry M. Diagnostic work-up in cardiomyopathies: bridging the gap between clinical phenotypes and final diagnosis. A position statement from the ESC Working Group on Myocardial and Pericardial Diseases European heart journal 2013;34 (19):1448-1458 [PubMed]
  • van Rijsingen Ingrid A. W. Dilated cardiomyopathy: translating genetic defects into clinical care. Towards personalized medicine in dilated cardiomyopathy 2013. 177p. ISBN 9789088916199. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Pinto Y. M., Wilde A. A. M.; Co-supervisor: Christiaans I.)
  • Maggioni Aldo P., Dahlström Ulf, Filippatos Gerasimos, Chioncel Ovidiu, Crespo Leiro Marisa, Drozdz Jaroslaw, Fruhwald Friedrich, Gullestad Lars, Logeart Damien, Fabbri Gianna, Urso Renato, Metra Marco, Parissis John, Persson Hans, Ponikowski Piotr, Rauchhaus Mathias, Voors Adriaan A., Wendelboe Nielsen Olav, Zannad Faiez, Tavazzi Luigi, Maggioni Aldo, Voors Adriaan, Alonso Angeles, Ferrari Roberto, Komajda Michel, Wood David, Manini Malika, Taylor Charles, Laroche Cécile, Fiorucci Emanuela, Lucci Donata, Gonzini Lucio, Auer J., Oberrauner A., Fruhwald F., Schumacher M., Ebner C., Hallas A., Espersen G., Gustafsson F., Mattsson N., Wendelboe Nielsen O., Egstrup K., Aagaard S., Gohr T., Huld K., Knudsen A. Sejr, Refsgaard J., Charniot J., Pinto Y. EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot) European journal of heart failure 2013;15 (7):808-817 [PubMed]
  • van Rijsingen Ingrid A. W., Nannenberg Eline A., Arbustini Eloisa, Elliott Perry M., Mogensen Jens, Hermans-van Ast Johanna F., van der Kooi Anneke J., van Tintelen J. Peter, van den Berg Maarten P., Grasso Maurizia, Serio Alessandra, Jenkins Sharon, Rowland Camilla, Richard Pascale, Wilde Arthur A. M., Perrot Andreas, Pankuweit Sabine, Zwinderman Aeilko H., Charron Philippe, Christiaans Imke, Pinto Yigal M. Gender-specific differences in major cardiac events and mortality in lamin A/C mutation carriers European journal of heart failure 2013;15 (4):376-384 [PubMed]
  • van Spaendonck-Zwarts Karin Y., van Rijsingen Ingrid A. W., van den Berg Maarten P., Lekanne Deprez Ronald H., Post Jan G., van Mil Anneke M., Asselbergs Folkert W., Christiaans Imke, van Langen Irene M., Wilde Arthur A. M., de Boer Rudolf A., Jongbloed Jan D. H., Pinto Yigal M., van Tintelen J. Peter Genetic analysis in 418 index patients with idiopathic dilated cardiomyopathy: overview of 10 years' experience European journal of heart failure 2013;15 (6):628-636 [PubMed]
  • Hermans M. C. E. Getting a grip on myotonic dystrophy type 1 2013. [UvA Dissertations Online] Univeriteit van Maastricht: Faculty of Health, Medicine and Life Sciences. (Supervisor: Pinto Y.; Co-supervisors: Faber C. G., Merkies I. S. J.)
  • van Rijsingen Ingrid A. W., Bakker Annemieke, Azim Donija, Hermans-van Ast Johanna F., van der Kooi Anneke J., van Tintelen J. Peter, van den Berg Maarten P., Christiaans Imke, Lekanne dit Deprez Ronald H., Wilde Arthur A. M., Zwinderman Aeilko H., Meijers Joost C. M., Grootemaat Anita E., Nieuwland Rienk, Pinto Yigal M., Pinto-Sietsma Sara-Joan Lamin A/C mutation is independently associated with an increased risk of arterial and venous thromboembolic complications International journal of cardiology 2013;168 (1):472-477 [PubMed]
  • Amin Ahmad S., Pinto Yigal M., Wilde Arthur A. M. Long QT syndrome: beyond the causal mutation Journal of physiology 2013;591 (Part 17):4125-4139 [PubMed]
  • Heymans Stephane, Corsten Maarten F., Verhesen Wouter, Carai Paolo, van Leeuwen Rick E. W., Custers Kevin, Peters Tim, Hazebroek Mark, Stöger Lauran, Wijnands Erwin, Janssen Ben J., Creemers Esther E., Pinto Yigal M., Grimm Dirk, Schürmann Nina, Vigorito Elena, Thum Thomas, Stassen Frank, Yin Xiaoke, Mayr Manuel, de Windt Leon J., Lutgens Esther, Wouters Kristiaan, de Winther Menno P. J., Zacchigna Serena, Giacca Mauro, van Bilsen Marc, Papageorgiou Anna-Pia, Schroen Blanche Macrophage microRNA-155 promotes cardiac hypertrophy and failure Circulation 2013;128 (13):1420-1432 [PubMed]
  • Tijsen Anke J. M. MicroRNAs in cardiac diseases. The devil is in the details 2013. 291p. ISBN 9789461918581. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)
  • Elzenaar I., Pinto Y. M., van Oort R. J. MicroRNAs in heart failure: new targets in disease management Clinical pharmacology and therapeutics 2013;94 (4):480-489 [PubMed]
  • van Rijsingen Ingrid A. W., van der Kooi Anneke J., Pinto Yigal M. Sudden cardiac death in dilated cardiomyopathy and skeletal muscular dystrophyin: Ihor Gussak, Charles Antzelevitch, Arthur A. M. Wilde, Brian D. Powell, Michael J. Ackerman, Win-Kuang Shen, editors. Electrical Diseases of the Heart. Volume 2: Diagnosis and Treatment. London: Springer; 2013. p. 25-40, ISBN 9781447149774
  • El Azzouzi Hamid, Leptidis Stefanos, Dirkx Ellen, Hoeks Joris, van Bree Bianca, Brand Karl, McClellan Elizabeth A., Poels Ella, Sluimer Judith C., van den Hoogenhof Maarten M. G., Armand Anne-Sophie, Yin Xiaoke, Langley Sarah, Bourajjaj Meriem, Olieslagers Serve, Krishnan Jaya, Vooijs Marc, Kurihara Hiroki, Stubbs Andrew, Pinto Yigal M., Krek Wilhelm, Mayr Manuel, da Costa Martins Paula A., Schrauwen Patrick, de Windt Leon J. The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation Cell metabolism 2013;18 (3):341-354 [PubMed]
  • Al-Saaidi Rasha, Rasmussen Torsten B., Palmfeldt Johan, Nissen Peter H., Beqqali Abdelaziz, Hansen Jakob, Pinto Yigal M., Boesen Thomas, Mogensen Jens, Bross Peter The LMNA mutation p.Arg321Ter associated with dilated cardiomyopathy leads to reduced expression and a skewed ratio of lamin A and lamin C proteins Experimental cell research 2013;319 (19):3010-3019 [PubMed]
  • Wijnen Wino J., Pinto Yigal M., Creemers Esther E. The therapeutic potential of miRNAs in cardiac fibrosis: where do we stand? Journal of cardiovascular translational research 2013;6 (6):899-908 [PubMed]

2012

  • Tijsen Anke J., Pinto Yigal M., Creemers Esther E. Circulating microRNAs as diagnostic biomarkers for cardiovascular diseases American journal of physiology. Heart and circulatory physiology 2012;303 (9):H1085-H1095 [PubMed]
  • Creemers Esther E., Tijsen Anke J., Pinto Yigal M. Circulating MicroRNAs Novel Biomarkers and Extracellular Communicators in Cardiovascular Disease? Circulation research 2012;110 (3):483-495 [PubMed]
  • Amin Ahmad S. Modifiers of phenotype in inheritable arrhythmia syndromes; from bedside to cell Off Page, www.offpage.nl; 2012. 237p. ISBN 9789461821065. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wilde Arthur A. M., Pinto Yigal M.; Co-supervisor: Tan Hanno L.)
  • Eurlings Luc W., Sanders-van Wijk Sandra, van Kimmenade Roland, Osinski Aart, van Helmond Lidwien, Vallinga Maud, Crijns Harry J., van Dieijen-Visser Marja P., Brunner-La Rocca Hans-Peter, Pinto Yigal M. Multimarker Strategy for Short-Term Risk Assessment in Patients With Dyspnea in the Emergency Department The MARKED (Multi mARKer Emergency Dyspnea)-Risk Score Journal of the American College of Cardiology 2012;60 (17):1668-1677 [PubMed]
  • Tijsen Anke J., Pinto Yigal M., Creemers Esther E. Non-cardiomyocyte microRNAs in heart failure Cardiovascular research 2012;93 (4):573-582 [PubMed]
  • Narula Nupoor, Favalli Valentina, Tarantino Paolo, Grasso Maurizia, Pilotto Andrea, Bellazzi Riccardo, Serio Alessandra, Gambarin Fabiana I., Charron Philippe, Meder Benjamin, Pinto Yigal, Elliott Perry M., Mogensen Jens, Bolognesi Martino, Bollati Michela, Arbustini Eloisa Quantitative Expression of the Mutated Lamin A/C Gene in Patients With Cardiolaminopathy Journal of the American College of Cardiology 2012;60 (19):1916-1920 [PubMed]
  • Leenders Joost J., Wijnen Wino J., van der Made Ingeborg, Hiller Monika, Swinnen Melissa, VandenDriessche Thierry, Chuah Marinee, Pinto Yigal M., Creemers Esther E. Repression of Cardiac Hypertrophy by KLF15: Underlying Mechanisms and Therapeutic Implications PLoS ONE 2012;7 (5):e36754 [PubMed]
  • van Rijsingen Ingrid A. W., Arbustini Eloisa, Elliott Perry M., Mogensen Jens, Hermans-van Ast Johanna F., van der Kooi Anneke J., van Tintelen J. Peter, van den Berg Maarten P., Pilotto Andrea, Pasotti Michele, Jenkins Sharon, Rowland Camilla, Aslam Uzma, Wilde Arthur A. M., Perrot Andreas, Pankuweit Sabine, Zwinderman Aeilko H., Charron Philippe, Pinto Yigal M. Risk Factors for Malignant Ventricular Arrhythmias in Lamin A/C Mutation Carriers A European Cohort Study Journal of the American College of Cardiology 2012;59 (5):493-500 [PubMed]
  • Hermans Mieke C. E., Faber Catharina G., Bekkers Sebastiaan C. A. M., de Die-Smulders Christine E. M., Gerrits Monique M., Merkies Ingemar S. J., Snoep Gabriel, Pinto Yigal M., Schalla Simon Structural and functional cardiac changes in myotonic dystrophy type 1: a cardiovascular magnetic resonance study Journal of cardiovascular magnetic resonance 2012;14 (1):48 [PubMed]
  • Leenders Joost J. G. Three fingers on the brake. Kruppel-like factor 15, a repressor of cardiac gene expression 2012. 189p. ISBN 9789461912718. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)
  • van Wijk Sandra, Jacobs Leo, Eurlings Luc W., van Kimmenade Roland, Lemmers Roosmarijn, Broos Pieter, Bekers Otto, Prins Martin H., Crijns Harry J., Pinto Yigal M., van Dieijen-Visser Marja P., Brunner-La Rocca Hans-Peter Troponin T Measurements by High-Sensitivity vs Conventional Assays for Risk Stratification in Acute Dyspnea Clinical chemistry 2012;58 (1):284-292 [PubMed]
  • Amin Ahmad S., Giudicessi John R., Tijsen Anke J., Spanjaart Anne M., Reckman Yolan J., Klemens Christine A., Tanck Michael W., Kapplinger Jamie D., Hofman Nynke, Sinner Moritz F., Müller Martina, Wijnen Wino J., Tan Hanno L., Bezzina Connie R., Creemers Esther E., Wilde Arthur A. M., Ackerman Michael J., Pinto Yigal M. Variants in the 3 untranslated region of the KCNQ1-encoded K(v)7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner European heart journal 2012;33 (6):714-723 [PubMed]

2011

  • van Almen Geert C., Swinnen Melissa, Carai Paolo, Verhesen Wouter, Cleutjens Jack P. M., D'hooge Jan, Verheyen Fons K., Pinto Yigal M., Schroen Blanche, Carmeliet Peter, Heymans Stephane Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy Journal of molecular and cellular cardiology 2011;51 (3):318-328 [PubMed]
  • Marsman Roos F., Bardai Abdennasser, Postma Alex V., Res Jan C. J., Koopmann Tamara T., Beekman Leander, van der Wal Allard C., Pinto Yigal M., Lekanne Deprez Ronald H., Wilde Arthur A. M., Jordaens Luc J., Bezzina Connie R. A complex double deletion in LMNA underlies progressive cardiac conduction disease, atrial arrhythmias, and sudden death Circulation. Cardiovascular genetics 2011;4 (3):280-287 [PubMed]
  • Pinto Yigal M., Wilde Arthur A. A. M., van Rijsingen Ingrid A. W., Christiaans Imke, Deprez Ronald H. Lekanne, Elliott Perry M. Clinical utility gene card for: hypertrophic cardiomyopathy (type 1-14) European journal of human genetics 2011;19 (8):10.1038/ejhg.2010.24 [PubMed]
  • van Rijsingen I. A. W., Bekkers S. C. A. M., Schalla S., Hermans-van Ast J. F., Snoep G., Alzand B. S. N., Arens Y. H. J. M., van den Wijngaard A., Crijns H. J. G. M., Pinto Y. M. Exercise related ventricular arrhythmias are related to cardiac fibrosis in hypertrophic cardiomyopathy mutation carriers Netherlands heart journal 2011;19 (4):168-174 [PubMed]
  • Creemers Esther E., Wilde Arthur A., Pinto Yigal M. Heart failure: advances through genomics Nature reviews. Genetics 2011;12 (5):357-362 [PubMed]
  • Kubben L. P. Lamin interA/Ctors: from the premature to senescence 2011. [UvA Dissertations Online] Univeriteit van Maastricht: Faculty of Health, Medicine and Life Sciences. (Supervisor: Pinto Y.; Co-supervisors: Vonken J. W., Mistelli T.)
  • Creemers Esther E., Pinto Yigal M. Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart Cardiovascular research 2011;89 (2):265-272 [PubMed]
  • van Rijsingen I. A. W., Pinto Y. M., Kok W. E. M. Onduidelijkheden in de diagnostiek van hartfalen Nederlands tijdschrift voor geneeskunde 2011;155 (10):A3159 [PubMed]
  • Koitabashi Norimichi, Danner Thomas, Zaiman Ari L., Pinto Yigal M., Rowell Janelle, Mankowski Joseph, Zhang Dou, Nakamura Taishi, Takimoto Eiki, Kass David A. Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload Journal of clinical investigation 2011;121 (6):2301-2312 [PubMed]
  • Kubben Nard, Voncken Jan Willem, Konings Gonda, van Weeghel Michel, van den Hoogenhof Maarten Mg, Gijbels Marion, van Erk Arie, Schoonderwoerd Kees, van den Bosch Bianca, Dahlmans Vivian, Calis Chantal, Houten Sander M., Misteli Tom, Pinto Yigal M. Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins Nucleus (Austin, Tex.) 2011;2 (3):195-207 [PubMed]
  • Elliott Perry, Baker Robert, Pasquale Ferdinando, Quarta Giovanni, Ebrahim Hatim, Mehta Atul B., Hughes Derralynn A., Anastasakis Aristides, Autore Camillo, Musumeci Maria Beatrice, Frenneaux Michael, Gimeno Juan, Tiina Heliö, Kuusisto Johanna, Aalto-Setäla Katriina, McKeown Pascal, Monserrat Lorenzo, Fernandez Xusto, Pacileo Giuseppe, Limongelli Giuseppe, Rapezzi Claudio, Biagini Elena, ten Cate Folkert J., Wilde Arthur A. M., Pinto Yigal M., Christiaans Imke, Zachara Elisabetta Prevalence of Anderson-Fabry disease in patients with hypertrophic cardiomyopathy: the European Anderson-Fabry Disease survey Heart (British Cardiac Society) 2011;97 (23):1957-1960 [PubMed]
  • Eurlings Luc W. M., Pinto Yigal M. Reports of Heart Failure Trials and the Dissociation With the Prevailing Clinical Practice Reply Journal of the American College of Cardiology 2011;58 (1):90-91 [PubMed]
  • Leenders Joost J., Pinto Yigal M., Creemers Esther E. Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling Journal of molecular and cellular cardiology 2011;51 (2):156-167 [PubMed]

2010

  • Eurlings Luc W. M., Pinto Yigal M., Dennert Robert M., Bekkers Sebastiaan C. A. M. Author reply: Consider potential pitfalls, myopathy and chromosomal abnormalities when diagnosing left ventricular hypertrabeculation/noncompaction International journal of cardiology 2010;144 (1):129-131
  • van Langen I. M., Arens Y., Baars H., Bokenkamp R., Delhaas T., Dooijes D., Lekanne Deprez Ronald H., Majoor-Krakauer D., ten Cate F. J., Michels M., van Mil A., Pinto Y., Schiphorst A., van der Smagt J. J., van Tintelen J. P. Genetic diagnostics and genetic counselling in Hypertrophic Cardiomyopathy (HCM) Netherlands heart journal 2010;18 (3):144-+
  • Hermans M. C. E., Pinto Y. M., Merkies I. S. J., de Die-Smulders C. E. M., Crijns H. J. G. M., Faber C. G. Hereditary muscular dystrophies and the heart Neuromuscular disorders 2010;20 (8):479-492 [PubMed]
  • Germans Tjeerd, Russel Iris K., Gotte Marco J. W., Spreeuwenberg Marieke D., Doevendans Pieter A., Pinto Yigal M., van der Geest Rob J., van der Velden Jolanda, Wilde Arthur A. M., van Rossum Albert C. How do hypertrophic cardiomyopathy mutations affect myocardial function in carriers with normal wall thickness? Assessment with cardiovascular magnetic resonance Journal of cardiovascular magnetic resonance 2010;12 (1):13 [PubMed]
  • Mohammed Asim A., van Kimmenade Roland R. J., Richards Mark, Bayes-Genis Antoni, Pinto Yigal, Moore Stephanie A., Januzzi James L. Hyponatremia, natriuretic peptides, and outcomes in acutely decompensated heart failure: results from the International Collaborative of NT-proBNP Study Circulation. Heart failure 2010;3 (3):354-361 [PubMed]
  • Eurlings Luc W. M., van Pol Petra E. J., Kok Wouter E., van Wijk Sandra, Lodewijks-van der Bolt Cara, Balk Aggie H. M. M., Lok Dirk J. A., Crijns Harry J. G. M., van Kraaij Dave J. W., de Jonge Nicolaas, Meeder Joan G., Prins Martin, Pinto Yigal M. Management of Chronic Heart Failure Guided by Individual N-Terminal Pro-B-Type Natriuretic Peptide Targets Results of the PRIMA (Can PRo-brain-natriuretic peptide guided therapy of chronic heart failure IMprove heart fAilure morbidity and mortality?) Study Journal of the American College of Cardiology 2010;56 (25):2090-2100 [PubMed]
  • Swinnen Melissa Matricellular proteins: crucial regulators of cardiac remodelingMaastricht: Procopia NV; 2010. 153p. ISBN 9789090252162. [UvA Dissertations Online] Academisch Ziekenhuis Maastricht-Universiteit van Maastricht en Vesalius Research Center- Leuven University: Afdeling Cardiologie. (Supervisors: Pinto Y. M., Carmeliet P.; Co-supervisor: Heymans Stephane)
  • Tijsen Anke J., Creemers Esther E., Moerland Perry D., Pinto Yigal M. MicroRNAs As Circulating Biomarkers for Heart Failure: Questions About MiR-423-5p Response Circulation research 2010;106 (9):E9
  • Tijsen Anke J., Creemers Esther E., Moerland Perry D., de Windt Leon J., van der Wal Allard C., Kok Wouter E., Pinto Yigal M. MiR423-5p As a Circulating Biomarker for Heart Failure Circulation research 2010;106 (6):1035-U63 [PubMed]
  • Baggish Aaron L., van Kimmenade Roland R. J., Pinto Yigal, Richards A. Mark, Lainchbury John, Bayes-Genis Antoni, Santaló Miquel, Ordonez-Llanos Jordi, Januzzi James L. New York Heart Association class versus amino-terminal pro-B type natriuretic peptide for acute heart failure prognosis Biomarkers 2010;15 (4):307-314 [PubMed]
  • Folkeringa R. J., de Vos C., Pinto Y. M., Habets J., de Leeuw P. W., Tieleman R. G., Prins M. H., van Dieijen-Visser M., Crijns H. J. G. M. No effect of rosuvastatin on left ventricular hypertrophy in patients with hypertension: a prospective randomised open-label study with blinded endpoint assessment International journal of cardiology 2010;145 (1):156-158 [PubMed]
  • Leenders Joost J., Wijnen Wino J., Hiller Monika, van der Made Inge, Lentink Viola, van Leeuwen Rick E., Herias Veronica, Pokharel Saraswati, Heymans Stephane, de Windt Leon J., Hoydal Morten A., Pinto Yigal M., Creemers Esther E. Regulation of Cardiac Gene Expression by KLF15, a Repressor of Myocardin Activity Journal of biological chemistry 2010;285 (35):27449-27456 [PubMed]
  • Schellings Mark W. M., Vanhoutte Davy, van Almen Geert C., Swinnen Melissa, Leenders Joost J. G., Kubben Nard, van Leeuwen Rick E. W., Hofstra Leo, Heymans Stephane, Pinto Yigal M. Syndecan-1 Amplifies Angiotensin II-Induced Cardiac Fibrosis Hypertension 2010;55 (2):249-U87 [PubMed]
  • Christiaans Imke, Birnie Erwin, van Langen Irene M., van Spaendonck-Zwarts Karin Y., van Tintelen J. Peter, van den Berg Maarten P., Atsma Douwe E., Helderman-van den Enden Apollonia T. J. M., Pinto Yigal M., Hermans-van Ast J. F., Bonsel Gouke J., Wilde Arthur A. M. The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers: focus on predictive screening European heart journal 2010;31 (7):842-848 [PubMed]
  • Diercks Gilles F., van Tintelen J. Peter, Tio Rene A., Kerstjens-Frederikse Wilhelmina S., Pinto Yigal M., Suurmeijer Albert J. Ultrastructural pathology of the nuclear envelope in familial lamin A/C cardiomyopathy Cardiovascular pathology 2010;19 (4):e135-e136 [PubMed]

2009

  • Schellings Mark W. M., Vanhoutte Davy, Swinnen Melissa, Cleutjens Jack P., Debets Jacques, van Leeuwen Rick E. W., D'hooge Jan, van de Werf Frans, Carmeliet Peter, Pinto Yigal M., Sage E. Helene, Heymans Stephane Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction Journal of experimental medicine 2009;206 (1):113-123 [PubMed]
  • Swinnen Melissa, Vanhoutte Davy, van Almen Geert C., Hamdani Nazha, Schellings Mark W. M., D'hooge Jan, van der Velden Jolanda, Weaver Matthew S., Sage E. Helene, Bornstein Paul, Verheyen Fons K., VandenDriessche Thierry, Chuah Marinee K., Westermann Dirk, Paulus Walter J., van de Werf Frans, Schroen Blanche, Carmeliet Peter, Pinto Yigal M., Heymans Stephane Absence of thrombospondin-2 causes age-related dilated cardiomyopathy Circulation 2009;120 (16):1585-1597 [PubMed]
  • Nieuwlaat Robby, Eurlings Luc W., Cleland John G., Cobbe Stuart M., Vardas Panos E., Capucci Alessandro, López-Sendòn José L., Meeder Joan G., Pinto Yigal M., Crijns Harry J. G. M. Atrial fibrillation and heart failure in cardiology practice: reciprocal impact and combined management from the perspective of atrial fibrillation: results of the Euro Heart Survey on atrial fibrillation Journal of the American College of Cardiology 2009;53 (18):1690-1698 [PubMed]
  • Koitabashi Norimichi, Bedja Djahida, Zaiman Ari L., Pinto Yigal M., Zhang Manling, Gabrielson Kathleen L., Takimoto Eiki, Kass David A. Avoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models Circulation research 2009;105 (1):12-15 [PubMed]
  • Wilde Arthur A. M., Pinto Yigal M. Cost-effectiveness of genotyping in inherited arrhythmia syndromes: are we getting value for the money? Circulation. Arrhythmia and electrophysiology 2009;2 (1):1-3 [PubMed]
  • van Rijsingen I. A. W., Hermans-van Ast J. F., Arens Y. H. J. M., Schalla S. M., de Die-Smulders C. E. M., van den Wijngaard A., Pinto Y. M. Hypertrophic cardiomyopathy family with double-heterozygous mutations; does disease severity suggest doubleheterozygosity? Netherlands heart journal 2009;17 (12):458-463 [PubMed]
  • Zandbergen Harmen R., Sharma Umesh C., Gupta Sudhir, Verjans Johan W. H., van den Borne Susanne, Pokharel Saraswati, van Brakel Thomas, Duijvestijn Adriaan, van Rooijen Nico, Maessen Jos G., Reutelingsperger Chris, Pinto Yigal M., Narula Jagat, Hofstra Leo Macrophage depletion in hypertensive rats accelerates development of cardiomyopathy Journal of cardiovascular pharmacology and therapeutics 2009;14 (1):68-75 [PubMed]
  • Duisters Rudy F., Tijsen Anke J., Schroen Blanche, Leenders Joost J., Lentink Viola, van der Made Ingeborg, Herias Veronica, van Leeuwen Rick E., Schellings Mark W., Barenbrug Paul, Maessen Jos G., Heymans Stephane, Pinto Yigal M., Creemers Esther E. miR-133 and miR-30 Regulate Connective Tissue Growth Factor Implications for a Role of MicroRNAs in Myocardial Matrix Remodeling Circulation research 2009;104 (2):170-U61 [PubMed]
  • Pinto Y. M., Wilde A. A.M., Hermans-van Ast J. F., Van Langen I. M., Van Tintelen J. P., Atsma D. E., Arens Y. M., Marcelis C. L., Ten Cate F. J., Vd Smagt J. J., Houweling A. C. National registry for patients and families with a familial heart disease Netherlands heart journal 2009;17 (2):81
  • van Kimmenade Roland R. J., Januzzi James L., Bakker Jaap A., Houben Alphonse J., Rennenberg Roger, Kroon Abraham A., Crijns Harry J. G. M., van Dieijen-Visser Marja P., de Leeuw Peter W., Pinto Yigal M. Renal clearance of B-type natriuretic peptide and amino terminal pro-B-type natriuretic peptide a mechanistic study in hypertensive subjects Journal of the American College of Cardiology 2009;53 (10):884-890 [PubMed]
  • Eurlings Luc W. M., Pinto Yigal M., Dennert Robert M., Bekkers Sebastiaan C. A. M. Reversible isolated left ventricular non-compaction? International journal of cardiology 2009;136 (2):e35-e36 [PubMed]

2008

  • DeFilippi Christopher, van Kimmenade Roland R. J., Pinto Yigal M. Amino-terminal pro-B-type natriuretic peptide testing in renal disease American journal of cardiology 2008;101 (3A):82-88 [PubMed]
  • da Costa Martins Paula A., Bourajjaj Meriem, Gladka Monika, Kortland Mara, van Oort Ralph J., Pinto Yigal M., Molkentin Jeffery D., de Windt Leon J. Conditional dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling Circulation 2008;118 (15):1567-1576 [PubMed]
  • van Kimmenade Roland R. J., Pinto Yigal M., Januzzi James L. Importance and interpretation of intermediate (gray zone) amino-terminal pro-B-type natriuretic peptide concentrations American journal of cardiology 2008;101 (3A):39-42 [PubMed]
  • Petretto Enrico, Sarwar Rizwan, Grieve Ian, Lu Han, Kumaran Mande K., Muckett Phillip J., Mangion Jonathan, Schroen Blanche, Benson Matthew, Punjabi Prakash P., Prasad Sanjay K., Pennell Dudley J., Kiesewetter Chris, Tasheva Elena S., Corpuz Lolita M., Webb Megan D., Conrad Gary W., Kurtz Theodore W., Kren Vladimir, Fischer Judith, Hubner Norbert, Pinto Yigal M., Pravenec Michal, Aitman Timothy J., Cook Stuart A. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass Nature genetics 2008;40 (5):546-552 [PubMed]
  • Fox Kim, Ford Ian, Steg P. Gabriel, Tendera Michal, Ferrari Roberto, Grancelli H., Freedman B., Eber B., Vanoverschelde J. L., Finkov B., Yotov Y., Tardif J. C., Hu D., Lau C., Hradec J., Hildebrandt P., Eha J., Peuhkurinen K., Danchin N., Steg P. G., Meinertz T., Vardas P., Borbola J., Mulcahy D., Maggioni A., Erglis A., Jirgensons J., Kalnins U., Laucevicius A., Dickstein K., Ruzyllo W., Tendera M., Seabra-Gomes R., Capalneanu R., Belenkov Y., Mareev Y., Murin J., Rakovec P., Macaya C., Dellborg M., Lüscher T. U., van Gilst W., Oto A., Ford I., Fox K., Hall A., Parkhomenko A., Robertson M., Weir C., Pinto Y. M. Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial Lancet 2008;372 (9641):807-816 [PubMed]
  • Pinto Yigal M., Heymans Stephane Letter by Pinto and Heymans regarding article, "Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice" Circulation 2008;118 (20):e697 [PubMed]
  • Hermans Mieke C. E., Faber Catharina G., Pinto Yigal M. Sudden death in myotonic dystrophy New England journal of medicine 2008;359 (15):1626-8; author reply 1328-9 [PubMed]
  • Ferrari R., Ford I., Fox K., Steg P. G., Tendera M., Cohen Arazi H., Nul D. R., Ahuad Guerrero R. A., Luciardi H. L., Sinisi V. A., Perna E. R., Schygiel P. O., Sanjurjo M. S., Fernandez A. A., del Valle Lobo Marquez L. L., Fuselli J. J., Hasbani E., Ibañez J. O., Cartasegna L. R., Lembo L. A., Thierer J., Varini S., Buscema J. J., Orlandini A. D., Bustos B., Guzmán L. A., Luquez H. A., Amuchastegui M., Allall O. A., Iglesias R. M., Sokn F. J., Montaña O. R., Sanchez A., Vogel D., Eber B., Huber K., Lang I., Pichler A. N., Dendale P. A. C., Vanderheyden M., van Mieghem W., Chenu P., Friart A., Missault L., Vachiery J. L., Materne P., François B. A. A., Sirakova V., Penkov N., Pinto Y. M. The BEAUTIFUL study: randomized trial of ivabradine in patients with stable coronary artery disease and left ventricular systolic dysfunction - baseline characteristics of the study population Cardiology 2008;110 (4):271-282 [PubMed]

2007

  • Schellings Mark W., Löwenberg Bob, Pinto Yigal M. Another look at imatinib mesylate New England journal of medicine 2007;356 (11):1183; author reply 1183 [PubMed]
  • Bayes-Genis Antoni, Lloyd-Jones Donald M., van Kimmenade Roland R. J., Lainchbury John G., Richards A. Mark, Ordoñez-Llanos Jordi, Santaló Miquel, Pinto Yigal M., Januzzi James L. Effect of body mass index on diagnostic and prognostic usefulness of amino-terminal pro-brain natriuretic peptide in patients with acute dyspnea Archives of internal medicine 2007;167 (4):400-407 [PubMed]
  • Baggish Aaron L., van Kimmenade Roland, Bayes-Genis Antoni, Davis Mark, Lainchbury John G., Frampton Chris, Pinto Yigal, Richards Mark A., Januzzi James L. Hemoglobin and N-terminal pro-brain natriuretic peptide: Independent and synergistic predictors of mortality in patients with acute heart failure Results from the International Collaborative of NT-proBNP (ICON) Study Clinica chimica acta; international journal of clinical chemistry 2007;381 (2):145-150 [PubMed]
  • Vanhoutte Davy, Schellings Mark W. M., Götte Martin, Swinnen Melissa, Herias Veronica, Wild Martin K., Vestweber Dietmar, Chorianopoulos Emmanuel, Cortés Víctor, Rigotti Attilio, Stepp Mary-Ann, van de Werf Frans, Carmeliet Peter, Pinto Yigal M., Heymans Stephane Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction Circulation 2007;115 (4):475-482 [PubMed]
  • Fisch Sudeshna, Gray Susan, Heymans Stephane, Haldar Saptarsi M., Wang Baiqiu, Pfister Otmar, Cui Lei, Kumar Ajay, Lin Zhiyong, Sen-Banerjee Sucharita, Das Hiranmoy, Petersen Christine A., Mende Ulrike, Burleigh Barbara A., Zhu Yan, Pinto Yigal M., Liao Ronglih, Jain Mukesh K. Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy Proceedings of the National Academy of Sciences of the United States of America 2007;104 (17):7074-7079 [PubMed]
  • Schroen Blanche, Leenders Joost J., van Erk Arie, Bertrand Anne T., van Loon Mirjam, van Leeuwen Rick E., Kubben Nard, Duisters Rudy F., Schellings Mark W., Janssen Ben J., Debets Jacques J., Schwake Michael, Høydal Morten A., Heymans Stephane, Saftig Paul, Pinto Yigal M. Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy Journal of experimental medicine 2007;204 (5):1227-1235 [PubMed]
  • Schellings Mark W. M. Matricellular proteins: essential modulators of cardiac remodelingMaastricht: 2007. 142p. ISBN 9789090219936. [UvA Dissertations Online] Academisch Ziekenhuis Maastricht-Universiteit van Maastricht: Afdeling Cardiologie. (Supervisor: Pinto Yigal M.; Co-supervisor: Heymans Stephane)
  • de Borst Martin H., Diks Sander H., Bolbrinker Juliane, Schellings Mark W., van Dalen Mario B. A., Peppelenbosch Maikel P., Kreutz Reinhold, Pinto Yigal M., Navis Gerjan, van Goor Harry Profiling of the renal kinome: a novel tool to identify protein kinases involved in angiotensin II-dependent hypertensive renal damage American journal of physiology. Renal physiology 2007;293 (1):F428-F437 [PubMed]
  • van Tintelen J. Peter, Tio Rene A., Kerstjens-Frederikse Wilhelmina S., van Berlo Jop H., Boven Ludolf G., Suurmeijer Albert J. H., White Stefan J., den Dunnen Johan T., te Meerman Gerard J., Vos Yvonne J., van der Hout Annemarie H., Osinga Jan, van den Berg Maarten P., van Veldhuisen Dirk J., Buys Charles H. C. M., Hofstra Robert M. W., Pinto Yigal M. Severe myocardial fibrosis caused by a deletion of the 5' end of the lamin A/C gene Journal of the American College of Cardiology 2007;49 (25):2430-2439 [PubMed]
  • Germans T., Wilde A. A. M., van Echteld C. J. A., Kamp O., Pinto Y. M., van Rossum A. C. Structural abnormalities of the left ventricle in hypertrophic cardiomyopathy mutation carriers detectable before the development of hypertrophy Netherlands heart journal 2007;15 (4):161-163 [PubMed]
  • van Kimmenade Roland R. J., Pinto Yigal, Januzzi James L. When renal and cardiac insufficiencies intersect: is there a role for natriuretic peptide testing in the 'cardio-renal syndrome'? European heart journal 2007;28 (24):2960-2961 [PubMed]

2006

  • van Kimmenade Roland R. J., Januzzi James L., Baggish Aaron L., Lainchbury John G., Bayes-Genis Antoni, Richards A. Mark, Pinto Yigal M. Amino-terminal pro-brain natriuretic Peptide, renal function, and outcomes in acute heart failure: redefining the cardiorenal interaction? Journal of the American College of Cardiology 2006;48 (8):1621-1627 [PubMed]
  • van Haaften Rachel I. M., Schroen Blanche, Janssen Ben J. A., van Erk Arie, Debets Jacques J. M., Smeets Hubert J. M., Smits Jos F. M., van den Wijngaard Arthur, Pinto Yigal M., Evelo Chris T. A. Biologically relevant effects of mRNA amplification on gene expression profiles BMC bioinformatics 2006;7:200 [PubMed]
  • van Kimmenade Roland R. J. Clinical implementation of serological markers in heart failureMaastricht: 2006. 127p. ISBN 9789052785271. [UvA Dissertations Online] Academisch Ziekenhuis Maastricht-Universiteit van Maastricht: Afdeling Cardiologie. (Supervisors: Pinto Y. M., van Dieijen-Visser Marja P.)
  • Hermans J. F., Christiaans I., van Tintelen J. P., Wilde A. A. M., Pinto Y. M. GENCOR: a national registry for patients and families suffering from a familial heart disease in the Netherlands Netherlands heart journal 2006;14 (7-8):272-276 [PubMed]
  • Schroen Blanche Genomics analyses to identify new molecular switches in heart failureMaastricht: 2006. 152p. ISBN 9789090213385. [UvA Dissertations Online] Academisch Ziekenhuis Maastricht-Univeristeit van Maastricht: Afdeling Cardiologie. (Supervisors: Pinto Y. M., Crijns H. J. G. M.; Co-supervisor: Heymans Stephane)
  • Schellings Mark W. M., Baumann Marcus, van Leeuwen Rick E. W., Duisters Rudy F. J. J., Janssen Suzanne H. P., Schroen Blanche, Peutz-Kootstra Carine J., Heymans Stephane, Pinto Yigal M. Imatinib attenuates end-organ damage in hypertensive homozygous TGR(mRen2)27 rats Hypertension 2006;47 (3):467-474 [PubMed]
  • Heymans Stephane, Pauschinger Matthias, de Palma Armando, Kallwellis-Opara Angela, Rutschow Susanne, Swinnen Melissa, Vanhoutte Davy, Gao Fangye, Torpai Raimund, Baker Andrew H., Padalko Elisabeth, Neyts Johan, Schultheiss Heinz-Peter, van de Werf Frans, Carmeliet Peter, Pinto Yigal M. Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis Circulation 2006;114 (6):565-573 [PubMed]
  • Eurlings Luc W., Januzzi James L., Pinto Yigal M. Is acute heart failure a highly prevalent orphan disease? European heart journal 2006;27 (22):2619-2620 [PubMed]
  • van Kimmenade Roland, van Dielen François, Bakker Jaap, Nijhuis Jeroen, Crijns Harry, Buurman Wim, van Dieijen-Visser Marja, Greve Jan-Willem, Pinto Yigal Is brain natriuretic peptide production decreased in obese subjects? Journal of the American College of Cardiology 2006;47 (4):886-887 [PubMed]
  • Januzzi James L., van Kimmenade Roland, Lainchbury John, Bayes-Genis Antoni, Ordonez-Llanos Jordi, Santalo-Bel Miguel, Pinto Yigal M., Richards Mark NT-proBNP testing for diagnosis and short-term prognosis in acute destabilized heart failure: an international pooled analysis of 1256 patients: the International Collaborative of NT-proBNP Study European heart journal 2006;27 (3):330-337 [PubMed]
  • Meune Christophe, van Berlo Jop H., Anselme Frédéric, Bonne Gisèle, Pinto Yigal M., Duboc Denis Primary prevention of sudden death in patients with lamin A/C gene mutations New England journal of medicine 2006;354 (2):209-210 [PubMed]
  • Vanhoutte Davy, Schellings Mark, Pinto Yigal, Heymans Stephane Relevance of matrix metalloproteinases and their inhibitors after myocardial infarction: a temporal and spatial window Cardiovascular research 2006;69 (3):604-613 [PubMed]
  • Folkeringa Richard J., van Kraaij Dave J., Tieleman Robert G., Nieman Fred H. M., Pinto Yigal M., Crijns Harry J. G. M. Statins associated with reduced mortality in patients admitted for congestive heart failure Journal of cardiac failure 2006;12 (2):134-138 [PubMed]
  • Germans Tjeerd, Wilde Arthur A. M., Dijkmans Pieter A., Chai Wenxia, Kamp Otto, Pinto Yigal M., van Rossum Albert C. Structural abnormalities of the inferoseptal left ventricular wall detected by cardiac magnetic resonance imaging in carriers of hypertrophic cardiomyopathy mutations Journal of the American College of Cardiology 2006;48 (12):2518-2523 [PubMed]
  • van Kimmenade Roland R. J., Pinto Yigal M., Bayes-Genis Antoni, Lainchbury John G., Richards A. Mark, Januzzi James L. Usefulness of intermediate amino-terminal pro-brain natriuretic peptide concentrations for diagnosis and prognosis of acute heart failure American journal of cardiology 2006;98 (3):386-390 [PubMed]
  • van Kimmenade Roland R., Januzzi James L., Ellinor Patrick T., Sharma Umesh C., Bakker Jaap A., Low Adrian F., Martinez Abelardo, Crijns Harry J., MacRae Calum A., Menheere Paul P., Pinto Yigal M. Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure Journal of the American College of Cardiology 2006;48 (6):1217-1224 [PubMed]
  • van Berlo J. H. When Lamin A/C fails, the heart suffersMaastricht: Universitaire Pers Maastricht; 2006. 125p. ISBN 9789052785578. [UvA Dissertations Online] Academisch Ziekenhuis Maastricht, Universiteit van Maastricht: Afdeling Cardiologie. (Supervisors: Pinto Y. M., Crijns H. J. G. M.)

2005

  • Bekkers Sebastiaan C. A. M., Habets Jos H. M., Cheriex E. C., Palmans Andrea, Pinto Yigal, Hofstra Leo, Crijns Harry J. G. M. Abdominal aortic aneurysm screening during transthoracic echocardiography in an unselected population Journal of the American Society of Echocardiography 2005;18 (5):389-393 [PubMed]
  • van Berlo J. H., Voncken J. W., Kubben N., Broers J. L. V., Duisters R., van Leeuwen R. E. W., Crijns H. J. G. M., Ramaekers F. C. S., Hutchison C. J., Pinto Y. M. A-type lamins are essential for TGF-beta1 induced PP2A to dephosphorylate transcription factors Human molecular genetics 2005;14 (19):2839-2849 [PubMed]
  • Sharma Umesh C. Effects of macrophage activation and galectin-3 expression in hypertension-induced cardiac dysfunctionMaastricht: 2005. 128p. ISBN 9789064641169. [UvA Dissertations Online] Academisch Ziekenhuis Maastricht-Universiteit van Maastricht: Afdeling Cardiologie. (Supervisor: Maessen Jos G.; Co-supervisors: Pinto Yigal M., Carretero Oscar)
  • Heymans Stephane, Schroen Blanche, Vermeersch Pieter, Milting Hendrik, Gao Fangye, Kassner Astrid, Gillijns Hilde, Herijgers Paul, Flameng Willem, Carmeliet Peter, van de Werf Frans, Pinto Yigal M., Janssens Stefan Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart Circulation 2005;112 (8):1136-1144 [PubMed]
  • van Berlo Jop H., de Voogt Willem G., van der Kooi Anneke J., van Tintelen J. Peter, Bonne Gisèle, Yaou Rabah Ben, Duboc Denis, Rossenbacker Tom, Heidbüchel Hein, de Visser Marianne, Crijns Harry J. G. M., Pinto Yigal M. Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A/C mutations portend a high risk of sudden death? Journal of molecular medicine (Berlin, Germany) 2005;83 (1):79-83 [PubMed]
  • Sharma U. C., Hofstra L., Pinto Y. M., Maessen J. G. Real-time in vivo imaging of apoptotic cell membrane changes in monocytes and macrophages Apoptosis 2005;10 (5):1187-1189 [PubMed]
  • Wilde A. A. M., Pinto Y. M. The ECG of a (cardio)myopathy? Netherlands heart journal 2005;13 (10):373-383

2004

  • Folkeringa Richard J., Pinto Yigal M., Crijns Harry J. G. M. Aldosterone levels after angiotensin receptor blocker treatment Circulation 2004;109 (14):e182; author reply e182 [PubMed]
  • de Boer Rudolf A., Pokharel Saraswati, Flesch Markus, van Kampen Derk A., Suurmeijer Albert J. H., Boomsma Frans, van Gilst Wiek H., van Veldhuisen Dirk J., Pinto Yigal M. Extracellular signal regulated kinase and SMAD signaling both mediate the angiotensin II driven progression towards overt heart failure in homozygous TGR(mRen2)27 Journal of molecular medicine (Berlin, Germany) 2004;82 (10):678-687 [PubMed]
  • Sharma Umesh C., Pokharel Saraswati, van Brakel Thomas J., van Berlo Jop H., Cleutjens Jack P. M., Schroen Blanche, André Sabine, Crijns Harry J. G. M., Gabius Hans-J., Maessen Jos, Pinto Yigal M. Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction Circulation 2004;110 (19):3121-3128 [PubMed]
  • Pokharel Saraswati How the renin angiotensin system influences the cardiac matrix via transforming growth factor bèta signalingMaastricht: 2004. 144p. ISBN 9789090183558. [UvA Dissertations Online] Universiteit Maastricht: CARIM. (Supervisor: Crijns H. J. G. M.; Co-supervisor: Pinto Y. M.)
  • Diris Jart H. C., Hackeng Christian M., Kooman Jeroen P., Pinto Yigal M., Hermens Wim T., van Dieijen-Visser Marja P. Impaired renal clearance explains elevated troponin T fragments in hemodialysis patients Circulation 2004;109 (1):23-25 [PubMed]
  • Pokharel Saraswati, van Geel Peter P., Sharma Umesh C., Cleutjens Jack P. M., Bohnemeier Holger, Tian Xiao-Li, Schunkert Heribert, Crijns Harry J. G. M., Paul Martin, Pinto Yigal M. Increased myocardial collagen content in transgenic rats overexpressing cardiac angiotensin-converting enzyme is related to enhanced breakdown of N-acetyl-Ser-Asp-Lys-Pro and increased phosphorylation of Smad2/3 Circulation 2004;110 (19):3129-3135 [PubMed]
  • Schellings Mark W. M., Pinto Yigal M., Heymans Stephane Matricellular proteins in the heart: possible role during stress and remodeling Cardiovascular research 2004;64 (1):24-31 [PubMed]
  • van Berlo Jop H., Duboc Denis, Pinto Yigal M. Often seen but rarely recognised: cardiac complications of lamin A/C mutations European heart journal 2004;25 (10):812-814 [PubMed]
  • Tian Xiao-Li, Pinto Yigal Martin, Costerousse Olivier, Franz Wolfgang M., Lippoldt Andrea, Hoffmann Sigrid, Unger Thomas, Paul Martin Over-expression of angiotensin converting enzyme-1 augments cardiac hypertrophy in transgenic rats Human molecular genetics 2004;13 (14):1441-1450 [PubMed]
  • Sharma Umesh C., Barenbrug Paul, Pokharel Saraswati, Dassen Willem R. M., Pinto Yigal M., Maessen Jos G. Systematic review of the outcome of aortic valve replacement in patients with aortic stenosis Annals of thoracic surgery 2004;78 (1):90-95 [PubMed]
  • Wilde A. A. M., Pinto Y. M. Therapie van hypertrofische cardiomyopathiein: J. N. Keeman, P. W. de Leeuw, J. A. Mazel, F. G. Zitman, editors. Het medisch jaar 2004. Houten: Bohn Stafleu Van Loghum; 2004. p. 53-66
  • Schroen Blanche, Heymans Stephane, Sharma Umesh, Blankesteijn W. Matthijs, Pokharel Saraswati, Cleutjens Jack P. M., Porter J. Gordon, Evelo Chris T. A., Duisters Rudy, van Leeuwen Rick E. W., Janssen Ben J. A., Debets Jacques J. M., Smits Jos F. M., Daemen Mat J. A. P., Crijns Harry J. G. M., Bornstein Paul, Pinto Yigal M. Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy Circulation research 2004;95 (5):515-522 [PubMed]

2003

  • Bonne Gisèle, Yaou Rabah Ben, Béroud Christophe, Boriani Giuseppe, Brown Sue, de Visser Marianne, Duboc Denis, Ellis Juliet, Hausmanowa-Petrusewicz Irena, Lattanzi Giovanna, Merlini Luciano, Morris Glenn, Muntoni Francesco, Opolski Grzegorz, Pinto Yigal M., Sangiuolo Federica, Toniolo Daniela, Trembath Richard, van Berlo Jop H., van der Kooi Anneke J., Wehnert Manfred 108th ENMC international workshop, 3rd workshop of the myo-cluster project: euromen, 7th international emery-dreifuss muscular dystrophy (edmd) workshop, 13-15 september 2002, naarden, the netherlands Neuromuscular disorders 2003;13 (6):508-515 [PubMed]
  • Gschwend Simone, Buikema Hendrik, Henning Robert H., Pinto Yigal M., de Zeeuw Dick, van Gilst Wiek H. Endothelial dysfunction and infarct-size relate to impaired EDHF response in rat experimental chronic heart failure European journal of heart failure 2003;5 (2):147-154 [PubMed]
  • de Boer Rudolf A., Pinto Yigal M., Suurmeijer Albert J. H., Pokharel Saraswati, Scholtens Egbert, Humler Michael, Saavedra Juan M., Boomsma Frans, van Gilst Wiek H., van Veldhuisen Dirk J. Increased expression of cardiac angiotensin II type 1 (AT(1)) receptors decreases myocardial microvessel density after experimental myocardial infarction Cardiovascular research 2003;57 (2):434-442 [PubMed]
  • Pokharel Saraswati, Sharma Umesh C., Pinto Yigal M. Left ventricular hypertrophy: virtuous intentions, malign consequences international journal of biochemistry & cell biology 2003;35 (6):802-806 [PubMed]
  • Gschwend S., Henning R. H., Pinto Y. M., de Zeeuw D., van Gilst W. H., Buikema H. Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade British journal of pharmacology 2003;139 (7):1317-1325 [PubMed]
  • van Berlo Jop H., Pinto Yigal M. Polymorphisms in the RAS and cardiac function international journal of biochemistry & cell biology 2003;35 (6):932-943 [PubMed]
  • de Boer Rudolf A., Pinto Yigal M., van Veldhuisen Dirk J. The imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: the role of microvascular growth and abnormalities Microcirculation (New York, N.Y. 2003;10 (2):113-126 [PubMed]

2002

  • de Boer Rudolf A., van Geel Peter P., Pinto Yigal M., Suurmeijer Albert J. H., Crijns Harry J. G. M., van Gilst Wiek H., van Veldhuisen Dirk J. Efficacy of angiotensin II type 1 receptor blockade on reperfusion-induced arrhythmias and mortality early after myocardial infarction is increased in transgenic rats with cardiac angiotensin II type 1 overexpression Journal of cardiovascular pharmacology 2002;39 (4):610-619 [PubMed]
  • de Boer R. A., Henning R. H., Tio R. A., Pinto Y. M., Brouwer R. M. H. J., Ploeg R. J., Böhm M., van Gilst W. H., van Veldhuisen D. J. Identification of a specific pattern of downregulation in expression of isoforms of vascular endothelial growth factor in dilated cardiomyopathy Heart (British Cardiac Society) 2002;88 (4):412-414 [PubMed]
  • Gschwend Simone, Pinto-Sietsma Sara-Joan, Buikema Hendrik, Pinto Yigal M., van Gilst Wiek H., Schulz Angela, de Zeeuw Dick, Kreutz Reinhold Impaired coronary endothelial function in a rat model of spontaneous albuminuria Kidney international 2002;62 (1):181-191 [PubMed]
  • Hocher Berthold, Godes Michael, Olivier Jan, Weil Joachim, Eschenhagen Thomas, Slowinski Torsten, Neumayer Hans-H., Bauer Christian, Paul Martin, Pinto Yigal M. Inhibition of left ventricular fibrosis by tranilast in rats with renovascular hypertension Journal of hypertension 2002;20 (4):745-751 [PubMed]
  • Pokharel Saraswati, Rasoul Saman, Roks Anton J. M., van Leeuwen Rick E. W., van Luyn Marja J. A., Deelman Leo E., Smits Jos F., Carretero Oscar, van Gilst Wiek H., Pinto Yigal M. N-acetyl-Ser-Asp-Lys-Pro inhibits phosphorylation of Smad2 in cardiac fibroblasts Hypertension 2002;40 (2):155-161 [PubMed]
  • Tjeerdsma Geert, de Boer Rudolf A., Boomsma Frans, van den Berg Maarten P., Pinto Yigal M., van Veldhuisen Dirk J. Rapid bedside measurement of brain natriuretic peptide in patients with chronic heart failure International journal of cardiology 2002;86 (2-3):143-9; discussion 149-52 [PubMed]
  • Roks A. J. M., Henning R. H., Buikema H., Pinto Y. M., Kraak M. J. J., Tio R. A., de Zeeuw D., Haisma H. J., Wilschut J., van Gilst W. H. Recombinant Semliki Forest virus as a vector system for fast and selective in vivo gene delivery into balloon-injured rat aorta Gene therapy 2002;9 (2):95-101 [PubMed]

2001

  • de Boer R. A., Henning R. H., Suurmeijer A. J., Pinto Y. M., Olthof E., Kirkels J. H., van Gilst W. H., Crijns H. J., van Veldhuisen D. J. Early expression of natriuretic peptides and SERCA in mild heart failure: association with severity of the disease International journal of cardiology 2001;78 (1):5-12 [PubMed]
  • Rothermund L., Pinto Y. M., Vetter R., Herfort N., Kossmehl P., Neumayer H. H., Paul M., Kreutz R. Effects of angiotensin II subtype 1 receptor blockade on cardiac fibrosis and sarcoplasmic reticulum Ca2+ handling in hypertensive transgenic rats overexpressing the Ren2 gene Journal of hypertension 2001;19 (8):1465-1472 [PubMed]
  • Oosterga M., Voors A. A., Pinto Y. M., Buikema H., Grandjean J. G., Kingma J. H., Crijns H. J., van Gilst W. H. Effects of quinapril on clinical outcome after coronary artery bypass grafting (The QUO VADIS Study). QUinapril on Vascular Ace and Determinants of Ischemia American journal of cardiology 2001;87 (5):542-546 [PubMed]
  • van Geel P. P., Pinto Y. M., Zwinderman A. H., Henning R. H., van Boven A. J., Jukema J. W., Bruschke A. V., Kastelein J. J., van Gilst W. H. Increased risk for ischaemic events is related to combined RAS polymorphism Heart (British Cardiac Society) 2001;85 (4):458-462 [PubMed]
  • Hoffmann S., Krause T., van Geel P. P., Willenbrock R., Pagel I., Pinto Y. M., Buikema H., van Gilst W. H., Lindschau C., Paul M., Inagami T., Ganten D., Urata H. Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy Journal of molecular medicine (Berlin, Germany) 2001;79 (10):601-608 [PubMed]

2000

  • Oosterga M., Voors A. A., Buikema H., Pinto Y. M., Haber H. E., Ebels T., Morshuis W. J., Kingma J. H., Crijns H. J., van Gilst W. H. Angiotensin II formation in human vasculature after chronic ACE inhibition: a prospective, randomized, placebo-controlled study. QUO VADIS Investigators Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2000;14 (1):55-60 [PubMed]
  • van Geel P. P., Pinto Y. M., Voors A. A., Buikema H., Oosterga M., Crijns H. J., van Gilst W. H. Angiotensin II type 1 receptor A1166C gene polymorphism is associated with an increased response to angiotensin II in human arteries Hypertension 2000;35 (3):717-721 [PubMed]
  • Rothermund L., Pinto Y. M., Hocher B., Vetter R., Leggewie S., Kobetamehl P., Orzechowski H. D., Kreutz R., Paul M. Cardiac endothelin system impairs left ventricular function in renin-dependent hypertension via decreased sarcoplasmic reticulum Ca(2+) uptake Circulation 2000;102 (13):1582-1588 [PubMed]
  • Teisman A. C., van Veldhuisen D. J., Boomsma F., de Kam P. J., Tjeerdsma G., Pinto Y. M., de Zeeuw D., van Gilst W. H. Chronic beta-blocker treatment in patients with advanced heart failure. Effects on neurohormones International journal of cardiology 2000;73 (1):7-12; discussion 13-4 [PubMed]
  • Pinto Y. M., Pals G., Zijlstra J. G., Tulleken J. E. Ehlers-Danlos syndrome type IV New England journal of medicine 2000;343 (5):366-368 [PubMed]
  • Pinto Y. M., Bader M., Pesquero J. B., Tschöpe C., Scholtens E., van Gilst W. H., Buikema H. Increased kallikrein expression protects against cardiac ischemia FASEB journal 2000;14 (13):1861-1863 [PubMed]
  • Pinto Y. M., Pinto-Sietsma S. J., Philipp T., Engler S., Kossamehl P., Hocher B., Marquardt H., Sethmann S., Lauster R., Merker H. J., Paul M. Reduction in left ventricular messenger RNA for transforming growth factor beta(1) attenuates left ventricular fibrosis and improves survival without lowering blood pressure in the hypertensive TGR(mRen2)27 Rat Hypertension 2000;36 (5):747-754 [PubMed]

1999

  • Roks A. J., van Geel P. P., Pinto Y. M., Buikema H., Henning R. H., de Zeeuw D., van Gilst W. H. Angiotensin-(1-7) is a modulator of the human renin-angiotensin system Hypertension 1999;34 (2):296-301 [PubMed]
  • Pinto Y. M., van Geel P. P., Alkfaji H., van Veldhuisen D. J., van Gilst W. H. Dosing of ACE inhibitors in left ventricular dysfunction: does current clinical dosing provide optimal benefit? Journal of cardiovascular pharmacology 1999;34 (Suppl. 1):S13-S17 [PubMed]
  • Pinto Y. M., van Gelder I. C., Heeringa M., Crijns H. J. QT lengthening and life-threatening arrhythmias associated with fexofenadine Lancet 1999;353 (9157):980 [PubMed]
  • Pinto Y. M., van Gilst W. H. The ACE gene polymorphism: the good, the bad and the ugly Cardiovascular research 1999;43 (1):23-24 [PubMed]

1998

  • Böhm M., Ettelbrück S., Flesch M., van Gilst W. H., Knorr A., Maack C., Pinto Y. M., Paul M., Teisman A. C., Zolk O. Beta-adrenergic signal transduction following carvedilol treatment in hypertensive cardiac hypertrophy Cardiovascular research 1998;40 (1):146-155 [PubMed]
  • Teisman A. C., Pinto Y. M., Buikema H., Flesch M., Böhm M., Paul M., van Gilst W. H. Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats Journal of hypertension 1998;16 (12 Part 1):1759-1765 [PubMed]
  • Voors A. A., Pinto Y. M., Buikema H., Urata H., Oosterga M., Rooks G., Grandjean J. G., Ganten D., van Gilst W. H. Dual pathway for angiotensin II formation in human internal mammary arteries British journal of pharmacology 1998;125 (5):1028-1032 [PubMed]
  • Zolk O., Flesch M., Schnabel P., Teisman A. C., Pinto Y. M., van Gilst W. H., Paul M., Böhm M. Effects of quinapril, losartan and hydralazine on cardiac hypertrophy and beta-adrenergic neuroeffector mechanisms in transgenic (mREN2)27 rats British journal of pharmacology 1998;123 (3):405-412 [PubMed]
  • Bohnemeier H., Pinto Y. M., Horkay F., Tóth M., Juhász-Nagy A., Orzechowski H. D., Böhm M., Paul M. Endothelin converting-enzyme-1 mRNA expression in human cardiovascular disease Clinical and experimental hypertension (New York, N.Y. 1998;20 (4):417-437 [PubMed]
  • Bohnemeier H., Pinto Y. M., Horkay F., Tóth M., Juhász-Nagy A., Orzechowski H. D., Paul M. Endothelin-converting enzyme-1 mRNA expression in human cardiovascular disease Journal of cardiovascular pharmacology 1998;31 (Suppl. 1):S52-S54 [PubMed]
  • van Veldhuisen D. J., Genth-Zotz S., Brouwer J., Boomsma F., Netzer T., Man in 't Veld A. J., Pinto Y. M., Lie K. I., Crijns H. J. High- versus low-dose ACE inhibition in chronic heart failure: a double-blind, placebo-controlled study of imidapril Journal of the American College of Cardiology 1998;32 (7):1811-1818 [PubMed]
  • Stula M., Pinto Y. M., Gschwend S., Teisman A. C., van Gilst W. H., Böhm M., Dietz R., Paul M. Interaction of the renin-angiotensin system and the endothelin system in cardiac hypertrophy Journal of cardiovascular pharmacology 1998;31 (Suppl. 1):S403-S405 [PubMed]
  • van Geel P. P., Pinto Y. M., Buikema H., van Gilst W. H. Is the A1166C polymorphism of the angiotensin II type 1 receptor involved in cardiovascular disease? European heart journal 1998;19 (Suppl. G):G13-G17 [PubMed]
  • Pinto Y. M., Paul M., Ganten D. Lessons from rat models of hypertension: from Goldblatt to genetic engineering Cardiovascular research 1998;39 (1):77-88 [PubMed]
  • Pinto Y. M., Pinto S. J., Paul M., Merker H. J. The electron microscopic morphology of the common carotid artery in rats Annals of anatomy = Anatomischer Anzeiger 1998;180 (3):223-235 [PubMed]
  • Engler S., Paul M., Pinto Y. M. The TGR(mRen2)27 transgenic rat model of hypertension Regulatory peptides 1998;77 (1-3):3-8 [PubMed]

1997

  • Flesch M., Schiffer F., Zolk O., Pinto Y., Stasch J. P., Knorr A., Ettelbrück S., Böhm M. Angiotensin receptor antagonism and angiotensin converting enzyme inhibition improve diastolic dysfunction and Ca(2+)-ATPase expression in the sarcoplasmic reticulum in hypertensive cardiomyopathy Journal of hypertension 1997;15 (9):1001-1009 [PubMed]
  • Pinto Y. M., Buikema H., van Gilst W. H., Scholtens E., van Geel P. P., de Graeff P. A., Wagner J., Paul M. Cardiovascular end-organ damage in Ren-2 transgenic rats compared to spontaneously hypertensive rats Journal of molecular medicine (Berlin, Germany) 1997;75 (5):371-377 [PubMed]
  • Flesch M., Schiffer F., Zolk O., Pinto Y., Rosenkranz S., Hirth-Dietrich C., Arnold G., Paul M., Böhm M. Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy Hypertension 1997;30 (3 Part 1):383-391 [PubMed]
  • Buikema H., Pinto Y. M., van Geel P. P., Rooks G., de Langen C. D., de Graeff P. A., van Gilst W. H. Differential inhibition of plasma versus tissue ACE by utibapril: biochemical and functional evidence for inhibition of vascular ACE activity Journal of cardiovascular pharmacology 1997;29 (5):684-691 [PubMed]
  • Oosterga M., Voors A. A., de Kam P. J., Schunkert H., Pinto Y. M., Kingma J. H., van Gilst W. H. Plasma angiotensin-converting enzyme activity and left ventricular dilation after myocardial infarction Circulation 1997;95 (12):2607-2609 [PubMed]
  • Roks A., Buikema H., Pinto Y. M., van Gilst W. H. The renin-angiotensin system and vascular function. The role of angiotensin II, angiotensin-converting enzyme, and alternative conversion of angiotensin I Heart and vessels 1997;12 (Suppl. 12):119-124 [PubMed]
  • Roks A. J., Pinto Y. M., Paul M., Pries F., Stula M., Eschenhagen T., Orzechowski H. D., Gschwendt S., Wilschut J., van Gilst W. H. Vectors based on Semliki Forest virus for rapid and efficient gene transfer into non-endothelial cardiovascular cells: comparison to adenovirus Cardiovascular research 1997;35 (3):498-504 [PubMed]

1996

  • Pinto Y. M., Buikema H., van Gilst W. H., Lie K. I. Activated tissue renin-angiotensin systems add to the progression of heart failure Basic research in cardiology 1996;91 (Suppl. 2):85-90 [PubMed]
  • Pinto Y. M., van Veldhuisen D. J., Tjon-Ka-Jie R. T., Rooks G., Netzer T., Lie K. I. Dose-finding study of imidapril, a novel angiotensin converting enzyme inhibitor, in patients with stable chronic heart failure European journal of clinical pharmacology 1996;50 (4):265-268 [PubMed]
  • Buikema H., Pinto Y. M., Rooks G., Grandjean J. G., Schunkert H., van Gilst W. H. The deletion polymorphism of the angiotensin-converting enzyme gene is related to phenotypic differences in human arteries European heart journal 1996;17 (5):787-794 [PubMed]
  • Langheinrich M., Lee M. A., Böhm M., Pinto Y. M., Ganten D., Paul M. The hypertensive Ren-2 transgenic rat TGR (mREN2)27 in hypertension research. Characteristics and functional aspects American journal of hypertension 1996;9 (5):506-512 [PubMed]

1995

  • Pinto Y. M., van Gilst W. H., Kingma J. H., Schunkert H. Deletion-type allele of the angiotensin-converting enzyme gene is associated with progressive ventricular dilation after anterior myocardial infarction. Captopril and Thrombolysis Study Investigators Journal of the American College of Cardiology 1995;25 (7):1622-1626 [PubMed]
  • Pinto Y. M., Buikema H., van Gilst W. H. Hyperactive tissue renin-angiotensin systems in cardiovascular dysfunction: experimental evidence and clinical hypotheses Clinical and experimental hypertension (New York, N.Y. 1995;17 (3):441-468 [PubMed]

1994

  • Paul M., Pinto Y. M., Schunkert H., Ganten D., Böhm M. Activation of the renin-angiotensin system in heart failure and hypertrophy--studies in human hearts and transgenic rats European heart journal 1994;15 (Suppl. D):63-67 [PubMed]

1993

  • Schunkert H., Ingelfinger J. R., Hirsch Alan T., Pinto Y., Remme W. J., Jacob H., Dzau V. J. Feedback regulation of angiotensin converting enzyme activity and mRNA levels by angiotensin II Circulation research 1993;72 (2):312-318 [PubMed]
  • Pinto Y. M., de Smet B. G., van Gilst W. H., Scholtens E., Monnink S., de Graeff P. A., Wesseling H. Selective and time related activation of the cardiac renin-angiotensin system after experimental heart failure: relation to ventricular function and morphology Cardiovascular research 1993;27 (11):1933-1938 [PubMed]

1991

  • Pinto Y. M., van Wijngaarden J., van Gilst W. H., de Graeff P. A., Wesseling H. The effects of short- and long-term treatment with an ACE-inhibitor in rats with myocardial infarction Basic research in cardiology 1991;86 (Suppl. 1):165-172 [PubMed]

1990

  • Hirsch Alan T., Pinto Y. M., Schunkert H., Dzau V. J. Potential role of the tissue renin-angiotensin system in the pathophysiology of congestive heart failure American journal of cardiology 1990;66 (11):22D-30D; discussion 30D-32D [PubMed]