Prof. R.W. Sanders PhD publications

2021

• McCaul Nicholas, Quandte Matthias, Bontjer Ilja, van Zadelhoff Guus, Land Aafke, Sanders Rogier W., Braakman Ineke Intramolecular quality control: HIV-1 Envelope gp160 signal-peptide cleavage as a functional folding checkpoint bioRxiv 2021

2020

• Larsen Mads Delbo, de Graaf Erik L, Sonneveld Myrthe E, Plomp H Rosina, Nouta Jan, Hoepel Willianne, Chen Hung-Jen, Linty Federica, Visser Remco, Brinkhaus Maximilian, Šuštić Tonći, de Taeye Steven W, Bentlage Arthur E H, Toivonen Suvi, Koeleman Carolien A M, Sainio Susanna, Kootstra Neeltje A, Brouwer Philip J M, Geyer Chiara Elisabeth, Derksen Ninotska I L, Wolbink Gertjan, de Winther Menno, Sanders Rogier W, van Gils Marit J, de Bruin Sanne, Vlaar Alexander P J, Rispens Theo, den Dunnen Jeroen, Zaaijer Hans L, Wuhrer Manfred, Ellen van der Schoot C, Vidarsson Gestur Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity Science 2020 [PubMed]
• Wu Nicholas C., Yuan Meng, Liu Hejun, Lee Chang-Chun D., Zhu Xueyong, Bangaru Sandhya, Torres Jonathan L., Caniels Tom G., Brouwer Philip J. M., van Gils Marit J., Sanders Rogier W., Ward Andrew B., Wilson Ian A. An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain Cell reports 2020;33 (3) [PubMed]
• Yang Yuhe R., McCoy Laura E., van Gils Marit J., Andrabi Raiees, Turner Hannah L., Yuan Meng, Cottrell Christopher A., Ozorowski Gabriel, Voss James, Pauthner Matthias, Polveroni Thomas M., Messmer Terrence, Wilson Ian A., Sanders Rogier W., Burton Dennis R., Ward Andrew B. Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits Journal of virology 2020;94 (7) [PubMed]
• Pickering Suzanne, Betancor Gilberto, Galão Rui Pedro, Merrick Blair, Signell Adrian W., Wilson Harry D., Kia Ik Mark Tan, Seow Jeffrey, Graham Carl, Acors Sam, Kouphou Neophytos, Steel Kathryn J. A., Hemmings Oliver, Patel Amita, Nebbia Gaia, Douthwaite Sam, O'Connell Lorcan, Luptak Jakub, McCoy Laura E., Brouwer Philip, van Gils Marit J., Sanders Rogier W., Martinez Nunez Rocio, Bisnauthsing Karen, O'Hara Geraldine, MacMahon Eithne, Batra Rahul, Malim Michael H., Neil Stuart J. D., Doores Katie J., Edgeworth Jonathan D. Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings PLoS pathogens 2020;16 (9):e1008817 [PubMed]
• Liu Hejun, Wu Nicholas C, Yuan Meng, Bangaru Sandhya, Torres Jonathan L, Caniels Tom G, van Schooten Jelle, Zhu Xueyong, Lee Chang-Chun D, Brouwer Philip J M, van Gils Marit J, Sanders Rogier W, Ward Andrew B, Wilson Ian A Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity Immunity 2020;53 (6):1272-1280.e5 [PubMed]
• van der Velden Yme U., Villaudy Julien, Siteur - van Rijnstra Esther, van der Linden Cynthia A., Vink Monique A., Schermer Edith E., Weijer Kees, Berkhout Ben, Sanders Rogier W., van Gils Marit J. Diverse HIV-1 escape pathways from broadly neutralizing antibody PGDM1400 in humanized mice mAbs 2020;12 (1) [PubMed]
• Reiss Emma I. M. M., van Gils Marit J., Sanders Rogier W., de Bree Godelieve J. Een hiv-vaccin: Hoe ver zijn we? Nederlands tijdschrift voor geneeskunde 2020;164 (37)
• Derking Ronald, Allen Joel D., Cottrell Christopher A., Sliepen Kwinten, Seabright Gemma E., Lee Wen-Hsin, Rantalainen Kimmo, Antanasijevic Aleksandar, Copps Jeffrey, Yasmeen Anila, van der Woude Patricia, de Taeye Steven W., van den Kerkhof Tom L.G.M., Klasse P.J., Ozorowski Gabriel, van Gils Marit J., Moore John P., Ward Andrew B., Crispin Max, Sanders Rogier W. Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike bioRxiv 2020
• Klasse P. J., Ozorowski Gabriel, Sanders Rogier W., Moore John P. Env Exceptionalism: Why Are HIV-1 Env Glycoproteins Atypical Immunogens? Cell host & microbe 2020;27 (4):507-518 [PubMed]
• Nogal Bartek, McCoy Laura E., van Gils Marit J., Cottrell Christopher A., Voss James E., Andrabi Raiees, Pauthner Matthias, Liang Chi-Hui, Messmer Terrence, Nedellec Rebecca, Shin Mia, Turner Hannah L., Ozorowski Gabriel, Sanders Rogier W., Burton Dennis R., Ward Andrew B. HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite Science advances 2020;6 (23) [PubMed]
• Cottrell Christopher A., van Schooten Jelle, Bowman Charles A., Yuan Meng, Oyen David, Shin Mia, Morpurgo Robert, van der Woude Patricia, van Breemen Marielle, Torres Jonathan L., Patel Raj, Gross Justin, Sewall Leigh M., Copps Jeffrey, Ozorowski Gabriel, Nogal Bartek, Sok Devin, Rakasz Eva G., Labranche Celia, Vigdorovich Vladimir, Christley Scott, Carnathan Diane G., Sather D. Noah, Montefiori David, Silvestri Guido, Burton Dennis R., Moore John P., Wilson Ian A., Sanders Rogier W., Ward Andrew B., van Gils Marit J. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates PLoS pathogens 2020;16 (8) [PubMed]
• Seabright Gemma E., Cottrell Christopher A., van Gils Marit J., D'addabbo Alessio, Harvey David J., Behrens Anna-Janina, Allen Joel D., Watanabe Yasunori, Scaringi Nicole, Polveroni Thomas M., Maker Allison, Vasiljevic Snezana, de Val Natalia, Sanders Rogier W., Ward Andrew B., Crispin Max Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions Structure (London, England 2020;28 (8):897-909.e6 [PubMed]
• Ringe Rajesh P., Cruz Portillo Victor M., Dosenovic Pia, Ketas Thomas J., Ozorowski Gabriel, Nogal Bartek, Perez Lautaro, LaBranche Celia C., Lim Jillian, Francomano Erik, Wilson Ian A., Sanders Rogier W., Ward Andrew B., Montefiori David C., Nussenzweig Michel C., Klasse P. J., Cupo Albert, Moore John P. Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin Journal of virology 2020;94 (5) [PubMed]
• Schorcht Anna, van den Kerkhof Tom L. G. M., Cottrell Christopher A., Allen Joel D., Torres Jonathan L., Behrens Anna-Janina, Schermer Edith E., Burger Judith A., de Taeye Steven W., Torrents de la Peña Alba, Bontjer Ilja, Gumbs Stephanie, Ozorowski Gabriel, LaBranche Celia C., de Val Natalia, Yasmeen Anila, Klasse Per Johan, Montefiori David C., Moore John P., Schuitemaker Hanneke, Crispin Max, van Gils Marit J., Ward Andrew B., Sanders Rogier W. Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers Journal of virology 2020;94 (24) [PubMed]
• Marín María Q., Sliepen Kwinten, García-Arriaza Juan, Koekkoek Sylvie M., Pérez Patricia, Sorzano Carlos Óscar S., Gómez Carmen E., Sanders Rogier W., Esteban Mariano Optimized hepatitis C virus (HCV) e2 glycoproteins and their immunogenicity in combination with MVA-HCV Vaccines 2020;8 (3):1-25 [PubMed]
• Brouwer Philip J.M., Caniels Tom G., van der Straten Karlijn, Snitselaar Jonne L., Aldon Yoann, Bangaru Sandhya, Torres Jonathan L., Okba Nisreen M.A., Claireaux Mathieu, Kerster Gius, Bentlage Arthur E.H., van Haaren Marlies M., Guerra Denise, Burger Judith A., Schermer Edith E., Verheul Kirsten D., van der Velde Niels, van der Kooi Alex, van Schooten Jelle, van Breemen Mariëlle J., Bijl Tom P.L., Sliepen Kwinten, Aartse Aafke, Derking Ronald, Bontjer Ilja, Kootstra Neeltje A., Joost Wiersinga W., Vidarsson Gestur, Haagmans Bart L., Ward Andrew B., de Bree Godelieve J., Sanders Rogier W., van Gils Marit J. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability Science 2020;369 (6504):643-650 [PubMed]
• Schommers Philipp, Gruell Henning, Abernathy Morgan E., Tran My-Kim, Dingens Adam S., Gristick Harry B., Barnes Christopher O., Schoofs Till, Schlotz Maike, Vanshylla Kanika, Kreer Christoph, Weiland Daniela, Holtick Udo, Scheid Christof, Valter Markus M., van Gils Marit J., Sanders Rogier W., Vehreschild J. rg J., Cornely Oliver A., Lehmann Clara, Fätkenheuer Gerd, Seaman Michael S., Bloom Jesse D., Bjorkman Pamela J., Klein Florian Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody Cell 2020;180 (3):471-489.e22 [PubMed]
• Bermejo-Jambrina Marta, Eder Julia, Kaptein Tanja M., Helgers Leanne C., Brouwer Philip J.M., van Hamme John L., Vlaar Alexander P.J., van Baarle Frank E.H.P., de Bree Godelieve J., Nijmeijer Bernadien M., Koostra Neeltje A., van Gils Marit J., Sanders Rogier W., Geijtenbeek Teunis B. H. SARS-CoV-2 Infection and Transmission Depends on Heparan Sulfates and Is Blocked by Low Molecular Weight Heparins bioRxiv 2020
• Antanasijevic Aleksandar, Ueda George, Brouwer Philip J. M., Copps Jeffrey, Huang Deli, Allen Joel D., Cottrell Christopher A., Yasmeen Anila, Sewall Leigh M., Bontjer Ilja, Ketas Thomas J., Turner Hannah L., Berndsen Zachary T., Montefiori David C., Klasse Per Johan, Crispin Max, Nemazee David, Moore John P., Sanders Rogier W., King Neil P., Baker David, Ward Andrew B. Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens PLoS pathogens 2020;16 (8):e1008665 [PubMed]
• Ueda George, Antanasijevic Aleksandar, Fallas Jorge A., Sheffler William, Copps Jeffrey, Ellis Daniel, Hutchinson Geoffrey B., Moyer Adam, Yasmeen Anila, Tsybovsky Yaroslav, Park Young-Jun, Bick Matthew J., Sankaran Banumathi, Gillespie Rebecca A., Brouwer Philip Jm, Zwart Peter H., Veesler David, Kanekiyo Masaru, Graham Barney S., Sanders Rogier W., Moore John P., Klasse Per Johan, Ward Andrew B., King Neil P., Baker David Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens eLife 2020;9:1-30 [PubMed]
• Brouwer Philip J. M., Brinkkemper Mitch, Maisonnasse Pauline, Dereuddre-Bosquet Nathalie, Grobben Marloes, Claireaux Mathieu, de Gast Marlon, Marlin Romain, Chesnais Virginie, Diry Ségolène, Allen Joel D., Watanabe Yasunori, Giezen Julia M., Kerster Gius, Turner Hannah L., van der Straten Karlijn, van der Linden Cynthia A., Aldon Yoann, Naninck Thibaut, Bontjer Ilja, Burger Judith A., Poniman Meliawati, Mykytyn Anna Z., Okba Nisreen M. A., Schermer Edith E., van Breemen Marielle J., Ravichandran Rashmi, Caniels Tom G., van Schooten Jelle, Kahlaoui Nidhal, Contreras Vanessa, Lemaitre Julien, Chapon Catherine, Ho Tsong Fang Raphaël, Villaudy Julien, Sliepen Kwinten, van der Velden Yme U., Haagmans Bart L., de Bree Godelieve J., Ginoux Eric, Ward Andrew B., Crispin Max, King Neil P., van der Werf Sylvie, van Gils Marit J., Grand Roger Le, Sanders Rogier W. Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection bioRxiv 2020

2019

• Gach Johannes S., Mara Kane J. V., LaBranche Celia C., van Gils Marit J., McCoy Laura E., Klasse P. J., Montefiori David C., Sanders Rogier W., Moore John P., Forthal Donald N. Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes Journal of virology 2019;93 (20) [PubMed]
• de Bree Godelieve J., Sanders Rogier W. Broadly neutralising antibodies in post-treatment control Lancet HIV 2019;6 (5):e271-e272 [PubMed]
• Kumar Sonu, Sarkar Anita, Pugach Pavel, Sanders Rogier W., Moore John P., Ward Andrew B., Wilson Ian A. Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide Nature communications 2019;10 (1) [PubMed]
• Ringe Rajesh P., Pugach Pavel, Cottrell Christopher A., LaBranche Celia C., Seabright Gemma E., Ketas Thomas J., Ozorowski Gabriel, Kumar Sonu, Schorcht Anna, van Gils Marit J., Crispin Max, Montefiori David C., Wilson Ian A., Ward Andrew B., Sanders Rogier W., Klasse P. J., Moore John P. Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes Journal of virology 2019;93 (4) [PubMed]
• Yuan Meng, Cottrell Christopher A., Ozorowski Gabriel, van Gils Marit J., Kumar Sonu, Wu Nicholas C., Sarkar Anita, Torres Jonathan L., de Val Natalia, Copps Jeffrey, Moore John P., Sanders Rogier W., Ward Andrew B., Wilson Ian A. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies......... Cell host & microbe 2019;25 (6):873-883.e5 [PubMed]
• Whitaker Neal, Hickey John M., Kaur Kawaljit, Xiong Jian, Sawant Nishant, Cupo Albert, Lee Wen-Hsin, Ozorowski Gabriel, Medina-Ramírez Max, Ward Andrew B., Sanders Rogier W., Moore John P., Joshi Sangeeta B., Volkin David B., Dey Antu K. Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens Journal of pharmaceutical sciences 2019;108 (7):2264-2277 [PubMed]
• Brouwer Philip J. M., Antanasijevic Aleksandar, Berndsen Zachary, Yasmeen Anila, Fiala Brooke, Bijl Tom P. L., Bontjer Ilja, Bale Jacob B., Sheffler William, Allen Joel D., Schorcht Anna, Burger Judith A., Camacho Miguel, Ellis Daniel, Cottrell Christopher A., Behrens Anna-Janina, Catalano Marco, del Moral-Sánchez Iván, Ketas Thomas J., LaBranche Celia, van Gils Marit J., Sliepen Kwinten, Stewart Lance J., Crispin Max, Montefiori David C., Baker David, Moore John P., Klasse Per Johan, Ward Andrew B., King Neil P., Sanders Rogier W. Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle Nature communications 2019;10 (1):4272 [PubMed]
• Eggink Dirk, Bontjer Ilja, de Taeye Steven W., Langedijk Johannes P. M., Berkhout Ben, Sanders Rogier W. HIV-1 anchor inhibitors and membrane fusion inhibitors target distinct but overlapping steps in virus entry Journal of biological chemistry 2019;294 (15):5736-5746 [PubMed]
• Euler Zelda, VAN DEN Kerkhof Tom L., Kouyos Roger D., Tully Damien C., Allen Todd M., Trkola Alexandra, Sanders Rogier W., Schuitemaker Hanneke, VAN Gils Marit J. Lower Broadly Neutralizing Antibody Responses in Female Versus Male HIV-1 Infected Injecting Drug Users Viruses 2019;11 (4) [PubMed]
• Brouwer Philip J. M., Sanders Rogier W. Presentation of HIV-1 envelope glycoprotein trimers on diverse nanoparticle platforms Current opinion in HIV and AIDS 2019;14 (4):302-308 [PubMed]
• Torrents de la Peña Alba, Rantalainen Kimmo, Cottrell Christopher A., Allen Joel D., van Gils Marit J., Torres Jonathan L., Crispin Max, Sanders Rogier W., Ward Andrew B. Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics PLoS pathogens 2019;15 (7):e1007920 [PubMed]
• de Taeye Steven W., Go Eden P., Sliepen Kwinten, de la Peña Alba Torrents, Badal Kimberly, Medina-Ramírez Max, Lee Wen-Hsin, Desaire Heather, Wilson Ian A., Moore John P., Ward Andrew B., Sanders Rogier W. Stabilization of the V2 loop improves the presentation of V2 loop associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers Journal of biological chemistry 2019;294 (14):5616-5631 [PubMed]
• Sliepen Kwinten, Han Byung Woo, Bontjer Ilja, Mooij Petra, Garces Fernando, Behrens Anna-Janina, Rantalainen Kimmo, Kumar Sonu, Sarkar Anita, Brouwer Philip J. M., Hua Yuanzi, Tolazzi Monica, Schermer Edith, Torres Jonathan L., Ozorowski Gabriel, van der Woude Patricia, de la Peña Alba Torrents, van Breemen Mariëlle J., Camacho-Sánchez Juan Miguel, Burger Judith A., Medina-Ramírez Max, González Nuria, Alcami Jose, LaBranche Celia, Scarlatti Gabriella, van Gils Marit J., Crispin Max, Montefiori David C., Ward Andrew B., Koopman Gerrit, Moore John P., Shattock Robin J., Bogers Willy M., Wilson Ian A., Sanders Rogier W. Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence Nature communications 2019;10 (1) [PubMed]
• Raman Suresh C., Mejías-Pérez Ernesto, Gomez Carmen E., García-Arriaza Juan, Perdiguero Beatriz, Vijayan Aneesh, Pérez-Ruiz Mar, Cuervo Ana, Santiago C. sar, Sorzano Carlos Oscar S., Sánchez-Corzo Cristina, Moog Christiane, Burger Judith A., Schorcht Anna, Sanders Rogier W., Carrascosa José L., Esteban Mariano The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1 Frontiers in immunology 2019;10 [PubMed]
• Pauthner Matthias G, Nkolola Joseph P, Havenar-Daughton Colin, Murrell Ben, Reiss Samantha M, Bastidas Raiza, Prévost Jérémie, Nedellec Rebecca, von Bredow Benjamin, Abbink Peter, Cottrell Christopher A, Kulp Daniel W, Tokatlian Talar, Nogal Bartek, Bianchi Matteo, Li Hui, Lee Jeong Hyun, Butera Salvatore T, Evans David T, Hangartner Lars, Finzi Andrés, Wilson Ian A, Wyatt Richard T, Irvine Darrell J, Schief William R, Ward Andrew B, Sanders Rogier W, Crotty Shane, Shaw George M, Barouch Dan H, Burton Dennis R Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers Immunity 2019;50 (1):241-252.e6 [PubMed]

2018

• dey Antu K., Cupo Albert, Ozorowski Gabriel, Sharma Vaneet K., Behrens Anna-Janina, Go Eden P., Ketas Thomas J., Yasmeen Anila, Klasse Per J., Sayeed Eddy, Desaire Heather, Crispin Max, Wilson Ian A., Sanders Rogier W., Hassell Thomas, Ward Andrew B., Moore John P. cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate Biotechnology and bioengineering 2018;115 (4):885-899 [PubMed]
• Klasse P. J., Ketas Thomas J., Cottrell Christopher A., Ozorowski Gabriel, Debnath Gargi, Camara Diawoye, Francomano Erik, Pugach Pavel, Ringe Rajesh P., LaBranche Celia C., van Gils Marit J., Bricault Christine A., Barouch Dan H., Crotty Shane, Silvestri Guido, Kasturi Sudhir, Pulendran Bali, Wilson Ian A., Montefiori David C., Sanders Rogier W., Ward Andrew B., Moore John P. Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques PLoS pathogens 2018;14 (2):e1006913 [PubMed]
• Allen Joel D., Sanders Rogier W., Doores Katie J., Crispin Max Harnessing post-translational modifications for next-generation HIV immunogens Biochemical Society transactions 2018;46 (3):691-698 [PubMed]
• van Gils Marit J., Sanders Rogier W. Hitting HIV's Harpoon Immunity 2018;49 (1):14-15 [PubMed]
• Torrents de la Peña Alba, de Taeye Steven W., Sliepen Kwinten, LaBranche Celia C., Burger Judith A., Schermer Edith E., Montefiori David C., Moore John P., Klasse Per Johan, Sanders Rogier W. Immunogenicity in rabbits of SOSIP trimers from clades A, B and C, given individually, sequentially or in combinations Journal of virology 2018;92 (8):e01957-17 [PubMed]
• Bonsignori Mattia, Scott Eric, Wiehe Kevin, Easterhoff David, Alam S. Munir, Hwang Kwan-Ki, Cooper Melissa, Xia Shi-Mao, Zhang Ruijun, Montefiori David C., Henderson Rory, Nie Xiaoyan, Kelsoe Garnett, Moody M. Anthony, Chen Xuejun, Joyce M. Gordon, Kwong Peter D., Connors Mark, Mascola John R., McGuire Andrew T., Stamatatos Leonidas, Medina-Ramírez Max, Sanders Rogier W., Saunders Kevin O., Kepler Thomas B., Haynes Barton F. Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier Immunity 2018;49 (6):1162-1174 [PubMed]
• Behrens Anna-Janina, Kumar Abhinav, Medina-Ramirez Max, Cupo Albert, Marshall Kevin, Cruz Portillo Victor M., Harvey David J., Ozorowski Gabriel, Zitzmann Nicole, Wilson Ian A., Ward Andrew B., Struwe Weston B., Moore John P., Sanders Rogier W., Crispin Max Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages Journal of proteome research 2018;17 (3):987-999 [PubMed]
• van der Velden Yme U., Villaudy Julien, Siteur-van Rijnstra Esther, van der Linden Cynthia A., Frankin Esmay, Weijer Kees, Schermer Edith, Vink Monique A., Berkhout Ben, Sanders Rogier W., van Gils Marit J. Short Communication: Protective Efficacy of Broadly Neutralizing Antibody PGDM1400 Against HIV-1 Challenge in Humanized Mice AIDS research and human retroviruses 2018;34 (9):790-793 [PubMed]
• Struwe Weston B., Chertova Elena, Allen Joel D., Seabright Gemma E., Watanabe Yasunori, Harvey David J., Medina-Ramirez Max, Roser James D., Smith Rodman, Westcott David, Keele Brandon F., Bess Julian W., Sanders Rogier W., Lifson Jeffrey D., Moore John P., Crispin Max Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen Cell reports 2018;24 (8):1958-1966.e5 [PubMed]
• de Taeye Steven W., Torrents de la Peña Alba, Vecchione Andrea, Scutigliani Enzo, Sliepen Kwinten, Burger Judith A., van der Woude Patricia, Schorcht Anna, Schermer Edith E., van Gils Marit J., LaBranche Celia C., Montefiori David C., Wilson Ian A., Moore John P., Ward Andrew B., Sanders Rogier W. Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers Journal of biological chemistry 2018;293 (5):1688-1701 [PubMed]
• Torrents de la Peña Alba, Sanders Rogier W. Stabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodies Marit van Gils, m.j.vangils@amc.uva.nl; Rogier W Sanders, rws2002@med.cornell.edu Retrovirology 2018;15 (1) [PubMed]
• Schiffner Torben, Pallesen Jesper, Russell Rebecca A., Dodd Jonathan, de Val Natalia, LaBranche Celia C., Montefiori David, Tomaras Georgia D., Shen Xiaoying, Harris Scarlett L., Moghaddam Amin E., Kalyuzhniy Oleksandr, Sanders Rogier W., McCoy Laura E., Moore John P., Ward Andrew B., Sattentau Quentin J. Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins PLoS pathogens 2018;14 (5) [PubMed]
• Torrents de la Peña Alba Structure-based stabilization of HIV-1 trimer vaccines 2018. ISBN 9789462999626. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Berkhout B., Sanders R. W.)
• Derking Ronald, Sanders Rogier W. The bumpy road towards an HIV-1 vaccine MT: Bulletin of the Netherlands Society for Tropical Medicine and International Health 2018;57 (4):6-7
• van de Bovenkamp Fleur S., Derksen Ninotska I. L., van Breemen Mariëlle J., de Taeye Steven W., Ooijevaar-de Heer Pleuni, Sanders Rogier W., Rispens Theo Variable domain N-linked glycans acquired during antigen-specific immune responses can contribute to immunoglobulin G antibody stability Frontiers in immunology 2018;9 (APR) [PubMed]

2017

• de Vries Robert P., Tzarum Netanel, Peng Wenjie, Thompson Andrew J., Ambepitiya Wickramasinghe Iresha N., de la Pena Alba T. Torrents, van Breemen Marielle J., Bouwman Kim M., Zhu Xueyong, McBride Ryan, Yu Wenli, Sanders Rogier W., Verheije Monique H., Wilson Ian A., Paulson James C. A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors EMBO molecular medicine 2017;9 (9):1314-1325 [PubMed]
• Freund Natalia T., Wang Haoqing, Scharf Louise, Nogueira Lilian, Horwitz Joshua A., Bar-On Yotam, Golijanin Jovana, Sievers Stuart A., Sok Devin, Cai Hui, Cesar Lorenzi Julio C., Halper-Stromberg Ariel, Toth Ildiko, Piechocka-Trocha Alicja, Gristick Harry B., van Gils Marit J., Sanders Rogier W., Wang Lai-Xi, Seaman Michael S., Burton Dennis R., Gazumyan Anna, Walker Bruce D., West Anthony P., Bjorkman Pamela J., Nussenzweig Michel C. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller Science translational medicine 2017;9 (373):eaal2144 [PubMed]
• Medina-Ramírez Max, Garces Fernando, Escolano Amelia, Skog Patrick, de Taeye Steven W., del Moral-Sanchez Ivan, McGuire Andrew T., Yasmeen Anila, Behrens Anna-Janina, Ozorowski Gabriel, van den Kerkhof Tom L. G. M., Freund Natalia T., Dosenovic Pia, Hua Yuanzi, Gitlin Alexander D., Cupo Albert, van der Woude Patricia, Golabek Michael, Sliepen Kwinten, Blane Tanya, Kootstra Neeltje, van Breemen Mariëlle J., Pritchard Laura K., Stanfield Robyn L., Crispin Max, Ward Andrew B., Stamatatos Leonidas, Klasse Per Johan, Moore John P., Nemazee David, Nussenzweig Michel C., Wilson Ian A., Sanders Rogier W. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo Journal of experimental medicine 2017;214 (9):2573-2590 [PubMed]
• Pauthner Matthias, Havenar-Daughton Colin, Sok Devin, Nkolola Joseph P., Bastidas Raiza, Boopathy Archana V., Carnathan Diane G., Chandrashekar Abishek, Cirelli Kimberly M., Cottrell Christopher A., Eroshkin Alexey M., Guenaga Javier, Kaushik Kirti, Kulp Daniel W., Liu Jinyan, McCoy Laura E., Oom Aaron L., Ozorowski Gabriel, Post Kai W., Sharma Shailendra K., Steichen Jon M., de Taeye Steven W., Tokatlian Talar, Torrents de la Peña Alba, Butera Salvatore T., LaBranche Celia C., Montefiori David C., Silvestri Guido, Wilson Ian A., Irvine Darrell J., Sanders Rogier W., Schief William R., Ward Andrew B., Wyatt Richard T., Barouch Dan H., Crotty Shane, Burton Dennis R. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches Immunity 2017;46 (6):1073-1088.e6 [PubMed]
• Sullivan Jonathan T., Sulli Chidananda, Nilo Alberto, Yasmeen Anila, Ozorowski Gabriel, Sanders Rogier W., Ward Andrew B., Klasse P. J., Moore John P., Doranz Benjamin J. High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers Journal of virology 2017;91 (22):UNSP e00862-17 [PubMed]
• Capucci Silvia, Wee Edmund G., Schiffner Torben, LaBranche Celia C., Borthwick Nicola, Cupo Albert, Dodd Jonathan, Dean Hansi, Sattentau Quentin, Montefiori David, Klasse Per J., Sanders Rogier W., Moore John P., Hanke Tomáš HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers PLoS ONE 2017;12 (8):e0181886 [PubMed]
• Ringe Rajesh P., Ozorowski Gabriel, Yasmeen Anila, Cupo Albert, Cruz Portillo Victor M., Pugach Pavel, Golabek Michael, Rantalainen Kimmo, Holden Lauren G., Cottrell Christopher A., Wilson Ian A., Sanders Rogier W., Ward Andrew B., Klasse P. J., Moore John P. Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes Journal of virology 2017;91 (12):UNSP e00264-17 [PubMed]
• Torrents de la Peña Alba, Julien Jean-Philippe, de Taeye Steven W., Garces Fernando, Guttman Miklos, Ozorowski Gabriel, Pritchard Laura K., Behrens Anna-Janina, Go Eden P., Burger Judith A., Schermer Edith E., Sliepen Kwinten, Ketas Thomas J., Pugach Pavel, Yasmeen Anila, Cottrell Christopher A., Torres Jonathan L., Vavourakis Charlotte D., van Gils Marit J., Labranche Celia, Montefiori David C., Desaire Heather, Crispin Max, Klasse Per Johan, Lee Kelly K., Moore John P., Ward Andrew B., Wilson Ian A., Sanders Rogier W. Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization Cell reports 2017;20 (8):1805-1817 [PubMed]
• Sanders Rogier W., Moore John P. Native-like Env trimers as a platform for HIV-1 vaccine design Immunological reviews 2017;275 (1):161-182 [PubMed]
• Leles S. G., Mitra A., Flynn K. J., Stoecker D. K., Hansen P. J., Calbet A., McManus G. B., Sanders R. W., Caron D. A., Not F., Hallegraeff G. M., Pitta P., Raven J. A., Johnson M. D., Glibert P. M., Våge S. Oceanic protists with different forms of acquired phototrophy display contrasting biogeographies and abundance Proceedings. Biological sciences / The Royal Society 2017;284 (1860) [PubMed]
• van Gils Marit J., Sanders Rogier W. Opposites attract in bispecific antibody engineering Journal of biological chemistry 2017;292 (35):14718-14719 [PubMed]
• Ringe Rajesh P., Ozorowski Gabriel, Rantalainen Kimmo, Struwe Weston B., Matthews Katie, Torres Jonathan L., Yasmeen Anila, Cottrell Christopher A., Ketas Thomas J., LaBranche Celia C., Montefiori David C., Cupo Albert, Crispin Max, Wilson Ian A., Ward Andrew B., Sanders Rogier W., Klasse P. J., Moore John P. Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers Journal of virology 2017;91 (15):UNSP e00677-17 [PubMed]
• de Taeye Steven W. Stabilization of HIV-1 envelope glycoprotein trimers to induce neutralizing antibodies 2017. 288p. ISBN 9789462995413. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Berkhout B., Sanders R. W.)
• Medina-Ramírez Max, Sanders Rogier W., Sattentau Quentin J. Stabilized HIV-1 envelope glycoprotein trimers for vaccine use Current opinion in HIV and AIDS 2017;12 (3):241-249 [PubMed]
• Snapp Erik Lee, McCaul Nicholas, Quandte Matthias, Cabartova Zuzana, Bontjer Ilja, Källgren Carolina, Nilsson IngMarie, Land Aafke, von Heijne Gunnar, Sanders Rogier W., Braakman Ineke Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide eLife 2017;6:e26067 [PubMed]
• Mayer Christian T., Gazumyan Anna, Kara Ervin E., Gitlin Alexander D., Golijanin Jovana, Viant Charlotte, Pai Joy, Oliveira Thiago Y., Wang Qiao, Escolano Amelia, Medina-Ramirez Max, Sanders Rogier W., Nussenzweig Michel C. The microanatomic segregation of selection by apoptosis in the germinal center Science 2017;358 (6360):193-+ [PubMed]
• de Vries Robert P., Peng Wenjie, Grant Oliver C., Thompson Andrew J., Zhu Xueyong, Bouwman Kim M., de la Pena Alba T. Torrents, van Breemen Marielle J., Ambepitiya Wickramasinghe Iresha N., de Haan Cornelis A. M., Yu Wenli, McBride Ryan, Sanders Rogier W., Woods Robert J., Verheije Monique H., Wilson Ian A., Paulson James C. Three mutations switch H7N9 influenza to human-type receptor specificity PLoS pathogens 2017;13 (6):e1006390 [PubMed]
• Saunders Kevin O., Nicely Nathan I., Wiehe Kevin, Bonsignori Mattia, Meyerhoff R. Ryan, Parks Robert, Walkowicz William E., Aussedat Baptiste, Wu Nelson R., Cai Fangping, Vohra Yusuf, Park Peter K., Eaton Amanda, Go Eden P., Sutherland Laura L., Scearce Richard M., Barouch Dan H., Zhang Ruijun, Von Holle Tarra, Overman R. Glenn, Anasti Kara, Sanders Rogier W., Moody M. Anthony, Kepler Thomas B., Korber Bette, Desaire Heather, Santra Sampa, Letvin Norman L., Nabel Gary J., Montefiori David C., Tomaras Georgia D., Liao Hua-Xin, Alam S. Munir, Danishefsky Samuel J., Haynes Barton F. Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates Cell reports 2017;18 (9):2175-2188 [PubMed]

2016

• van Gils Marit J., van den Kerkhof Tom L. G. M., Ozorowski Gabriel, Cottrell Christopher A., Sok Devin, Pauthner Matthias, Pallesen Jesper, de Val Natalia, Yasmeen Anila, de Taeye Steven W., Schorcht Anna, Gumbs Stephanie, Johanna Inez, Saye-Francisco Karen, Liang Chi-Hui, Landais Elise, Nie Xiaoyan, Pritchard Laura K., Crispin Max, Kelsoe Garnett, Wilson Ian A., Schuitemaker Hanneke, Klasse Per Johan, Moore John P., Burton Dennis R., Ward Andrew B., Sanders Rogier W. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability Nature microbiology 2016;2 (2):16199 [PubMed]
• Derking Ronald Antigenic structure of the HIV-1 envelope glycoprotein trimer 2016. 221p. ISBN 9789462994263. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Sanders R. W.)
• Schiffner Torben, de Val Natalia, Russell Rebecca A., de Taeye Steven W., de la Peña Alba Torrents, Ozorowski Gabriel, Kim Helen J., Nieusma Travis, Brod Florian, Cupo Albert, Sanders Rogier W., Moore John P., Ward Andrew B., Sattentau Quentin J. Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens Journal of virology 2016;90 (2):813-828 [PubMed]
• Behrens Anna-Janina, Vasiljevic Snezana, Pritchard Laura K., Harvey David J., Andev Rajinder S., Krumm Stefanie A., Struwe Weston B., Cupo Albert, Kumar Abhinav, Zitzmann Nicole, Seabright Gemma E., Kramer Holger B., Spencer Daniel I. R., Royle Louise, Lee Jeong Hyun, Klasse Per J., Burton Dennis R., Wilson Ian A., Ward Andrew B., Sanders Rogier W., Moore John P., Doores Katie J., Crispin Max Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein Cell reports 2016;14 (11):2695-2706 [PubMed]
• Havenar-Daughton Colin, Reiss Samantha M., Carnathan Diane G., Wu Jennifer E., Kendric Kayla, Torrents de la Peña Alba, Kasturi Sudhir Pai, Dan Jennifer M., Bothwell Marcella, Sanders Rogier W., Pulendran Bali, Silvestri Guido, Crotty Shane Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique Journal of immunology (Baltimore, Md. 2016;197 (3):994-1002 [PubMed]
• Havenar-Daughton Colin, Carnathan Diane G., Torrents de la Peña Alba, Pauthner Matthias, Briney Bryan, Reiss Samantha M., Wood Jennifer S., Kaushik Kirti, van Gils Marit J., Rosales Sandy L., van der Woude Patricia, Locci Michela, Le Khoa M., de Taeye Steven W., Sok Devin, Mohammed Ata Ur Rasheed, Huang Jessica, Gumber Sanjeev, Garcia AnaPatricia, Kasturi Sudhir P., Pulendran Bali, Moore John P., Ahmed Rafi, Seumois Grégory, Burton Dennis R., Sanders Rogier W., Silvestri Guido, Crotty Shane Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer Cell reports 2016;17 (9):2195-2209 [PubMed]
• Sliepen Kwinten, Sanders Rogier W. HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies Expert review of vaccines 2016;15 (3):349-365 [PubMed]
• de Taeye Steven W., Moore John P., Sanders Rogier W. HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies Trends in immunology 2016;37 (3):221-232 [PubMed]
• Sliepen Kwinten HIV-1 envelope trimer fusion proteins and their applications 2016. 183p. ISBN 9789462993594. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Sanders R. W.)
• Eggink Dirk, de Taeye Steven W., Bontjer Ilja, Klasse Per Johan, Langedijk Johannes P. M., Berkhout Ben, Sanders Rogier W. HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike Journal of virology 2016;90 (23):10587-10599 [PubMed]
• van den Kerkhof Tom L. G. M., de Taeye Steven W., Boeser-Nunnink Brigitte D., Burton Dennis R., Kootstra Neeltje A., Schuitemaker Hanneke, Sanders Rogier W., van Gils Marit J. HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds Retrovirology 2016;13 (1):48 [PubMed]
• van den Kerkhof Tom L. G. M. HIV-1 vaccine design: Learning from natural infection 2016. 301p. ISBN 9789462993204. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schuitemaker J.; Co-supervisor: Sanders R. W.)
• Sanders Rogier W., Wilson Ian A., Moore John P. HiV's ACHILLES' HEEL Scientific American 2016;315 (6):50-55 [PubMed]
• McCoy Laura E., van Gils Marit J., Ozorowski Gabriel, Messmer Terrence, Briney Bryan, Voss James E., Kulp Daniel W., Macauley Matthew S., Sok Devin, Pauthner Matthias, Menis Sergey, Cottrell Christopher A., Torres Jonathan L., Hsueh Jessica, Schief William R., Wilson Ian A., Ward Andrew B., Sanders Rogier W., Burton Dennis R. Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies Cell reports 2016;16 (9):2327-2338 [PubMed]
• van den Kerkhof Tom L. G. M., van Gils Marit J., Boeser-Nunnink Brigitte D., Burger Judith A., Schuitemaker Hanneke, Sanders Rogier W. Probability of N332 glycan occupancy on HIV-1 gp120 modulates sensitivity to broadly neutralizing antibodies AIDS (London, England) 2016;30 (14):2179-2184 [PubMed]
• Klasse P. J., LaBranche Celia C., Ketas Thomas J., Ozorowski Gabriel, Cupo Albert, Pugach Pavel, Ringe Rajesh P., Golabek Michael, van Gils Marit J., Guttman Miklos, Lee Kelly K., Wilson Ian A., Butera Salvatore T., Ward Andrew B., Montefiori David C., Sanders Rogier W., Moore John P. Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C PLoS pathogens 2016;12 (9):e1005864 [PubMed]
• Tam Hok Hei, Melo Mariane B., Kang Myungsun, Pelet Jeisa M., Ruda Vera M., Foley Maria H., Hu Joyce K., Kumari Sudha, Crampton Jordan, Baldeon Alexis D., Sanders Rogier W., Moore John P., Crotty Shane, Langer Robert, Anderson Daniel G., Chakraborty Arup K., Irvine Darrell J. Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination Proceedings of the National Academy of Sciences of the United States of America 2016;113 (43):E6639-E6648 [PubMed]
• Cornelissen Marion, Euler Zelda, van den Kerkhof Tom L. G. M., van Gils Marit J., Boeser-Nunnink Brigitte D. M., Kootstra Neeltje A., Zorgdrager Fokla, Schuitemaker Hanneke, Prins Jan M., Sanders Rogier W., van der Kuyl Antoinette C. The Neutralizing Antibody Response in an Individual with Triple HIV-1 Infection Remains Directed at the First Infecting Subtype AIDS research and human retroviruses 2016;32 (10-11):1135-1142 [PubMed]

2015

• Garces Fernando, Lee Jeong Hyun, de Val Natalia, de la Pena Alba Torrents, Kong Leopold, Puchades Cristina, Hua Yuanzi, Stanfield Robyn L., Burton Dennis R., Moore John P., Sanders Rogier W., Ward Andrew B., Wilson Ian A. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans Immunity 2015;43 (6):1053-1063 [PubMed]
• Pugach Pavel, Ozorowski Gabriel, Cupo Albert, Ringe Rajesh, Yasmeen Anila, de Val Natalia, Derking Ronald, Kim Helen J., Korzun Jacob, Golabek Michael, de Los Reyes Kevin, Ketas Thomas J., Julien Jean-Philippe, Burton Dennis R., Wilson Ian A., Sanders Rogier W., Klasse P. J., Ward Andrew B., Moore John P. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene Journal of virology 2015;89 (6):3380-3395 [PubMed]
• Freund Natalia T., Horwitz Joshua A., Nogueira Lilian, Sievers Stuart A., Scharf Louise, Scheid Johannes F., Gazumyan Anna, Liu Cassie, Velinzon Klara, Goldenthal Ariel, Sanders Rogier W., Moore John P., Bjorkman Pamela J., Seaman Michael S., Walker Bruce D., Klein Florian, Nussenzweig Michel C. A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo PLoS pathogens 2015;11 (10):e1005238 [PubMed]
• Lee Jeong Hyun, Leaman Daniel P., Kim Arthur S., Torrents de la Peña Alba, Sliepen Kwinten, Yasmeen Anila, Derking Ronald, Ramos Alejandra, de Taeye Steven W., Ozorowski Gabriel, Klein Florian, Burton Dennis R., Nussenzweig Michel C., Poignard Pascal, Moore John P., Klasse Per Johan, Sanders Rogier W., Zwick Michael B., Wilson Ian A., Ward Andrew B. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike Nature communications 2015;6:8167 [PubMed]
• Guttman Miklos, Cupo Albert, Julien Jean-Philippe, Sanders Rogier W., Wilson Ian A., Moore John P., Lee Kelly K. Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env Nature communications 2015;6:6144 [PubMed]
• Sliepen Kwinten, Medina-Ramírez Max, Yasmeen Anila, Moore John P., Klasse Per Johan, Sanders Rogier W. Binding of inferred germline precursors of broadly neutralizing HIV-1 antibodies to native-like envelope trimers Virology 2015;486:116-120 [PubMed]
• Stax Martijn J., Mouser Emily E. I. M., van Montfort Thijs, Sanders Rogier W., de Vries Henry J. C., Dekker Henk L., Herrera Carolina, Speijer Dave, Pollakis Georgios, Paxton William A. Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes PLoS ONE 2015;10 (3):e0122020 [PubMed]
• Kong Leopold, Torrents de la Peña Alba, Deller Marc C., Garces Fernando, Sliepen Kwinten, Hua Yuanzi, Stanfield Robyn L., Sanders Rogier W., Wilson Ian A. Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer Acta crystallographica. Section D, Biological crystallography 2015;71 (Part 10):2099-2108 [PubMed]
• Derking Ronald, Ozorowski Gabriel, Sliepen Kwinten, Yasmeen Anila, Cupo Albert, Torres Jonathan L., Julien Jean-Philippe, Lee Jeong Hyun, van Montfort Thijs, de Taeye Steven W., Connors Mark, Burton Dennis R., Wilson Ian A., Klasse Per-Johan, Ward Andrew B., Moore John P., Sanders Rogier W. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer PLoS pathogens 2015;11 (3):e1004767 [PubMed]
• van der Sluis Renée M., van Capel Toni M. M., Speijer Dave, Sanders Rogier W., Berkhout Ben, de Jong Esther C., Jeeninga Rienk E., van Montfort Thijs Dendritic cell type-specific HIV-1 activation in effector T cells: implications for latent HIV-1 reservoir establishment AIDS (London, England) 2015;29 (9):1003-1014 [PubMed]
• Julien Jean-Philippe, Lee Jeong Hyun, Ozorowski Gabriel, Hua Yuanzi, Torrents de la Peña Alba, de Taeye Steven W., Nieusma Travis, Cupo Albert, Yasmeen Anila, Golabek Michael, Pugach Pavel, Klasse P. J., Moore John P., Sanders Rogier W., Ward Andrew B., Wilson Ian A. Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens Proceedings of the National Academy of Sciences of the United States of America 2015;112 (38):11947-11952 [PubMed]
• Sliepen Kwinten, van Montfort Thijs, Ozorowski Gabriel, Pritchard Laura K., Crispin Max, Ward Andrew B., Sanders Rogier W. Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer Biomolecules 2015;5 (4):2919-2934 [PubMed]
• Carrillo Jorge, Molinos-Albert Luis Manuel, Rodríguez de la Concepción Maria Luisa, Marfil Silvia, García Elisabet, Derking Ronald, Sanders Rogier W., Clotet Bonaventura, Blanco Julià Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals PLoS ONE 2015;10 (3):e0120648 [PubMed]
• Sanders Rogier W., van Gils Marit J., Derking Ronald, Sok Devin, Ketas Thomas J., Burger Judith A., Ozorowski Gabriel, Cupo Albert, Simonich Cassandra, Goo Leslie, Arendt Heather, Kim Helen J., Lee Jeong Hyun, Pugach Pavel, Williams Melissa, Debnath Gargi, Moldt Brian, van Breemen Mariëlle J., Isik Gözde, Medina-Ramírez Max, Back Jaap Willem, Koff Wayne C., Julien Jean-Philippe, Rakasz Eva G., Seaman Michael S., Guttman Miklos, Lee Kelly K., Klasse Per Johan, Labranche Celia, Schief William R., Wilson Ian A., Overbaugh Julie, Burton Dennis R., Ward Andrew B., Montefiori David C., Dean Hansi, Moore John P. HIV-1 neutralizing antibodies induced by native-like envelope trimers Science 2015;349 (6244):aac4223-154 [PubMed]
• Dosenovic Pia, von Boehmer Lotta, Escolano Amelia, Jardine Joseph, Freund Natalia T., Gitlin Alexander D., McGuire Andrew T., Kulp Daniel W., Oliveira Thiago, Scharf Louise, Pietzsch John, Gray Matthew D., Cupo Albert, van Gils Marit J., Yao Kai-Hui, Liu Cassie, Gazumyan Anna, Seaman Michael S., Björkman Pamela J., Sanders Rogier W., Moore John P., Stamatatos Leonidas, Schief William R., Nussenzweig Michel C. Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice Cell 2015;161 (7):1505-1515 [PubMed]
• de Taeye Steven W., Ozorowski Gabriel, Torrents de la Peña Alba, Guttman Miklos, Julien Jean-Philippe, van den Kerkhof Tom L. G. M., Burger Judith A., Pritchard Laura K., Pugach Pavel, Yasmeen Anila, Crampton Jordan, Hu Joyce, Bontjer Ilja, Torres Jonathan L., Arendt Heather, DeStefano Joanne, Koff Wayne C., Schuitemaker Hanneke, Eggink Dirk, Berkhout Ben, Dean Hansi, Labranche Celia, Crotty Shane, Crispin Max, Montefiori David C., Klasse P. J., Lee Kelly K., Moore John P., Wilson Ian A., Ward Andrew B., Sanders Rogier W. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes Cell 2015;163 (7):1702-1715 [PubMed]
• Sliepen Kwinten, van Montfort Thijs, Melchers Mark, Isik Gözde, Sanders Rogier W. Immunosilencing a highly immunogenic protein trimerization domain Journal of biological chemistry 2015;290 (12):7436-7442 [PubMed]
• McCoy Laura E., Falkowska Emilia, Doores Katie J., Le Khoa, Sok Devin, van Gils Marit J., Euler Zelda, Burger Judith A., Seaman Michael S., Sanders Rogier W., Schuitemaker Hanneke, Poignard Pascal, Wrin Terri, Burton Dennis R. Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies PLoS pathogens 2015;11 (8):e1005110 [PubMed]
• Ringe Rajesh P., Yasmeen Anila, Ozorowski Gabriel, Go Eden P., Pritchard Laura K., Guttman Miklos, Ketas Thomas A., Cottrell Christopher A., Wilson Ian A., Sanders Rogier W., Cupo Albert, Crispin Max, Lee Kelly K., Desaire Heather, Ward Andrew B., Klasse P. J., Moore John P. Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers Journal of virology 2015;89 (23):12189-12210 [PubMed]
• Hu Joyce K., Crampton Jordan C., Cupo Albert, Ketas Thomas, van Gils Marit J., Sliepen Kwinten, de Taeye Steven W., Sok Devin, Ozorowski Gabriel, Deresa Isaiah, Stanfield Robyn, Ward Andrew B., Burton Dennis R., Klasse Per Johan, Sanders Rogier W., Moore John P., Crotty Shane Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity Journal of virology 2015;89 (20):10383-10398 [PubMed]
• Sliepen Kwinten, Ozorowski Gabriel, Burger Judith A., van Montfort Thijs, Stunnenberg Melissa, Labranche Celia, Montefiori David C., Moore John P., Ward Andrew B., Sanders Rogier W. Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity Retrovirology 2015;12 (1):82 [PubMed]
• van Montfort Thijs, Thomas Adri A. M., Krawczyk Przemek M., Berkhout Ben, Sanders Rogier W., Paxton William A. Reactivation of Neutralized HIV-1 by Dendritic Cells Is Dependent on the Epitope Bound by the Antibody Journal of immunology (Baltimore, Md. 2015;195 (8):3759-3768 [PubMed]
• Alexander Marina R., Sanders Rogier W., Moore John P., Klasse Per Johan Short Communication: Virion Aggregation by Neutralizing and Nonneutralizing Antibodies to the HIV-1 Envelope Glycoprotein AIDS research and human retroviruses 2015;31 (11):1160-1165 [PubMed]
• Pritchard Laura K., Vasiljevic Snezana, Ozorowski Gabriel, Seabright Gemma E., Cupo Albert, Ringe Rajesh, Kim Helen J., Sanders Rogier W., Doores Katie J., Burton Dennis R., Wilson Ian A., Ward Andrew B., Moore John P., Crispin Max Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers Cell reports 2015;11 (10):1604-1613 [PubMed]
• Alexander Marina R., Ringe Rajesh, Sanders Rogier W., Voss James E., Moore John P., Klasse Per Johan What Do Chaotrope-Based Avidity Assays for Antibodies to HIV-1 Envelope Glycoproteins Measure? Journal of virology 2015;89 (11):5981-5995 [PubMed]

2014

• Yu Fei, Lu Lu, Liu Qi, Yu Xiaowen, Wang Lili, He Elaine, Zou Peng, Du Lanying, Sanders Rogier W., Liu Shuwen, Jiang Shibo ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2014;1838 (5):1296-1305 [PubMed]
• Isik Gözde, van Montfort Thijs, Chung Nancy P. Y., Moore John P., Sanders Rogier W. Autoantibodies induced by chimeric cytokine-HIV envelope glycoprotein immunogens Journal of immunology (Baltimore, Md. 2014;192 (10):4628-4635 [PubMed]
• Huang Jinghe, Kang Byong H., Pancera Marie, Lee Jeong Hyun, Tong Tommy, Feng Yu, Imamichi Hiromi, Georgiev Ivelin S., Chuang Gwo-Yu, Druz Aliaksandr, Doria-Rose Nicole A., Laub Leo, Sliepen Kwinten, van Gils Marit J., de la Peña Alba Torrents, Derking Ronald, Klasse Per-Johan, Migueles Stephen A., Bailer Robert T., Alam Munir, Pugach Pavel, Haynes Barton F., Wyatt Richard T., Sanders Rogier W., Binley James M., Ward Andrew B., Mascola John R., Kwong Peter D., Connors Mark Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface Nature 2014;515 (7525):138-142 [PubMed]
• Falkowska Emilia, Le Khoa M., Ramos Alejandra, Doores Katie J., Lee Jeong Hyun, Blattner Claudia, Ramirez Alejandro, Derking Ronald, van Gils Marit J., Liang Chi-Hui, McBride Ryan, von Bredow Benjamin, Shivatare Sachin S., Wu Chung-Yi, Chan-Hui Po-Ying, Liu Yan, Feizi Ten, Zwick Michael B., Koff Wayne C., Seaman Michael S., Swiderek Kristine, Moore John P., Evans David, Paulson James C., Wong Chi-Huey, Ward Andrew B., Wilson Ian A., Sanders Rogier W., Poignard Pascal, Burton Dennis R. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers Immunity 2014;40 (5):657-668 [PubMed]
• Guttman Miklos, Garcia Natalie K., Cupo Albert, Matsui Tsutomu, Julien Jean-Philippe, Sanders Rogier W., Wilson Ian A., Moore John P., Lee Kelly K. CD4-induced activation in a soluble HIV-1 Env trimer Structure (London, England 2014;22 (7):974-984 [PubMed]
• Doria-Rose Nicole A., Schramm Chaim A., Gorman Jason, Moore Penny L., Bhiman Jinal N., Dekosky Brandon J., Ernandes Michael J., Georgiev Ivelin S., Kim Helen J., Pancera Marie, Staupe Ryan P., Altae-Tran Han R., Bailer Robert T., Crooks Ema T., Cupo Albert, Druz Aliaksandr, Garrett Nigel J., Hoi Kam H., Kong Rui, Louder Mark K., Longo Nancy S., McKee Krisha, Nonyane Molati, O'Dell Sijy, Roark Ryan S., Rudicell Rebecca S., Schmidt Stephen D., Sheward Daniel J., Soto Cinque, Wibmer Constantinos Kurt, Yang Yongping, Zhang Zhenhai, Mullikin James C., Binley James M., Sanders Rogier W., Wilson Ian A., Moore John P., Ward Andrew B., Georgiou George, Williamson Carolyn, Abdool Karim Salim S., Morris Lynn, Kwong Peter D., Shapiro Lawrence, Mascola John R., Becker Jesse, Benjamin Betty, Blakesley Robert, Bouffard Gerry, Brooks Shelise, Coleman Holly, Dekhtyar Mila, Gregory Michael, Guan Xiaobin, Gupta Jyoti, Han Joel, Hargrove April, Ho Shi-ling, Johnson Taccara, Legaspi Richelle, Lovett Sean, Maduro Quino, Masiello Cathy, Maskeri Baishali, McDowell Jenny, Montemayor Casandra, Mullikin James, Park Morgan, Riebow Nancy, Schandler Karen, Schmidt Brian, Sison Christina, Stantripop Mal, Thomas James, Thomas Pam, Vemulapalli Meg, Young Alice Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies Nature 2014;509 (7498):55-62 [PubMed]
• Yasmeen Anila, Ringe Rajesh, Derking Ronald, Cupo Albert, Julien Jean-Philippe, Burton Dennis R., Ward Andrew B., Wilson Ian A., Sanders Rogier W., Moore John P., Klasse Per Johan Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits Retrovirology 2014;11:41 [PubMed]
• van den Kerkhof Tom L. G. M., Euler Zelda, van Gils Marit J., Boeser-Nunnink Brigitte D., Schuitemaker Hanneke, Sanders Rogier W. Early development of broadly reactive HIV-1 neutralizing activity in elite neutralizers AIDS (London, England) 2014;28 (8):1237-1240 [PubMed]
• Isik Gözde, Sliepen Kwinten, van Montfort Thijs, Sanders Rogier W. Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL PLoS ONE 2014;9 (9):e107683 [PubMed]
• Isik Gözde HIV-1 envelope glycoproteins with costimulatory domains for vaccine applications 2014. 229p. ISBN 9789053358986. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Sanders R. W.)
• Sanders Rogier W., Moore John P. HIV: A stamp on the envelope Nature 2014;514 (7523):437-438 [PubMed]
• van Gils Marit J., Sanders Rogier W. In vivo protection by broadly neutralizing HIV antibodies Trends in microbiology 2014;22 (10):550-551 [PubMed]
• Sok Devin, van Gils Marit J., Pauthner Matthias, Julien Jean-Philippe, Saye-Francisco Karen L., Hsueh Jessica, Briney Bryan, Lee Jeong Hyun, Le Khoa M., Lee Peter S., Hua Yuanzi, Seaman Michael S., Moore John P., Ward Andrew B., Wilson Ian A., Sanders Rogier W., Burton Dennis R. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex Proceedings of the National Academy of Sciences of the United States of America 2014;111 (49):17624-17629 [PubMed]
• Chung Nancy P. Y., Matthews Katie, Kim Helen J., Ketas Thomas J., Golabek Michael, de Los Reyes Kevin, Korzun Jacob, Yasmeen Anila, Sanders Rogier W., Klasse Per Johan, Wilson Ian A., Ward Andrew B., Marozsan Andre J., Moore John P., Cupo Albert Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies Retrovirology 2014;11 (1):33 [PubMed]
• Blattner Claudia, Lee Jeong Hyun, Sliepen Kwinten, Derking Ronald, Falkowska Emilia, de la Peña Alba Torrents, Cupo Albert, Julien Jean-Philippe, van Gils Marit, Lee Peter S., Peng Wenjie, Paulson James C., Poignard Pascal, Burton Dennis R., Moore John P., Sanders Rogier W., Wilson Ian A., Ward Andrew B. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers Immunity 2014;40 (5):669-680 [PubMed]
• Medina-Ramírez Max, Sanders Rogier W., Klasse Per Johan Targeting B-cell germlines and focusing affinity maturation: the next hurdles in HIV-1-vaccine development? Expert review of vaccines 2014;13 (4):449-452 [PubMed]

2013

• Sanders Rogier W., Derking Ronald, Cupo Albert, Julien Jean-Philippe, Yasmeen Anila, de Val Natalia, Kim Helen J., Blattner Claudia, de la Peña Alba Torrents, Korzun Jacob, Golabek Michael, de Los Reyes Kevin, Ketas Thomas J., van Gils Marit J., King C. Richter, Wilson Ian A., Ward Andrew B., Klasse P. J., Moore John P. A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies PLoS pathogens 2013;9 (9):e1003618 [PubMed]
• Isik Gözde, Chung Nancy P. Y., van Montfort Thijs, Menis Sergey, Matthews Katie, Schief William R., Moore John P., Sanders Rogier W. An HIV-1 Envelope Glycoprotein Trimer with an Embedded IL-21 Domain Activates Human B Cells PLoS ONE 2013;8 (6):e67309 [PubMed]
• Julien Jean-Philippe, Lee Jeong Hyun, Cupo Albert, Murin Charles D., Derking Ronald, Hoffenberg Simon, Caulfield Michael J., King C. Richter, Marozsan Andre J., Klasse Per Johan, Sanders Rogier W., Moore John P., Wilson Ian A., Ward Andrew B. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9 Proceedings of the National Academy of Sciences of the United States of America 2013;110 (11):213-218 [PubMed]
• van Gils Marit J., Sanders Rogier W. Broadly neutralizing antibodies against HIV-1: templates for a vaccine Virology 2013;435 (1):46-56 [PubMed]
• Julien Jean-Philippe, Sok Devin, Khayat Reza, Lee Jeong Hyun, Doores Katie J., Walker Laura M., Ramos Alejandra, Diwanji Devan C., Pejchal Robert, Cupo Albert, Katpally Umesh, Depetris Rafael S., Stanfield Robyn L., McBride Ryan, Marozsan Andre J., Paulson James C., Sanders Rogier W., Moore John P., Burton Dennis R., Poignard Pascal, Ward Andrew B., Wilson Ian A. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans PLoS pathogens 2013;9 (5):e1003342 [PubMed]
• Isik Gözde, van Montfort Thijs, Boot Maikel, Cobos Jiménez Viviana, Kootstra Neeltje A., Sanders Rogier W. Chimeric HIV-1 envelope glycoproteins with potent intrinsic granulocyte-macrophage colony-stimulating factor (GM-CSF) activity PLoS ONE 2013;8 (4):e60126 [PubMed]
• Ringe Rajesh P., Sanders Rogier W., Yasmeen Anila, Kim Helen J., Lee Jeong Hyun, Cupo Albert, Korzun Jacob, Derking Ronald, van Montfort Thijs, Julien Jean-Philippe, Wilson Ian A., Klasse Per Johan, Ward Andrew B., Moore John P. Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation Proceedings of the National Academy of Sciences of the United States of America 2013;110 (45):18256-18261 [PubMed]
• Matthews Katie, Chung Nancy P. Y., Klasse Per Johan, Moutaftsi Magda, Carter Darrick, Salazar André M., Reed Steven G., Sanders Rogier W., Moore John P. Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells PLoS ONE 2013;8 (5):e63785 [PubMed]
• Bontjer Ilja, Melchers Mark, Tong Tommy, van Montfort Thijs, Eggink Dirk, Montefiori David, Olson William C., Moore John P., Binley James M., Berkhout Ben, Sanders Rogier W. Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers PLoS ONE 2013;8 (6):e67484 [PubMed]
• Lyumkis Dmitry, Julien Jean-Philippe, de Val Natalia, Cupo Albert, Potter Clinton S., Klasse Per-Johan, Burton Dennis R., Sanders Rogier W., Moore John P., Carragher Bridget, Wilson Ian A., Ward Andrew B. Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer Science 2013;342 (6165):1484-1490 [PubMed]
• Julien Jean-Philippe, Cupo Albert, Sok Devin, Stanfield Robyn L., Lyumkis Dmitry, Deller Marc C., Klasse Per-Johan, Burton Dennis R., Sanders Rogier W., Moore John P., Ward Andrew B., Wilson Ian A. Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer Science 2013;342 (6165):1477-1483 [PubMed]
• van der Sluis Renée M., van Montfort Thijs, Pollakis Georgios, Sanders Rogier W., Speijer Dave, Berkhout Ben, Jeeninga Rienk E. Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes PLoS pathogens 2013;9 (3):e1003259-(15 p.) [PubMed]
• Baan Elly, de Ronde Anthony, Stax Martijn, Sanders Rogier W., Luchters Stanley, Vyankandondera Joseph, Lange Joep M., Pollakis Georgios, Paxton William A. HIV-1 autologous antibody neutralization associates with mother to child transmission PLoS ONE 2013;8 (7):e69274 [PubMed]
• Malherbe Delphine C., Sanders Rogier W., van Gils Marit J., Park Byung, Gomes Michelle M., Schuitemaker Hanneke, Barnett Susan, Haigwood Nancy L. HIV-1 envelope glycoprotein resistance to monoclonal antibody 2G12 is subject-specific and context-dependent in macaques and humans PLoS ONE 2013;8 (9):e75277 [PubMed]
• van den Kerkhof Tom L. G. M., Feenstra K. A., Euler Zelda, van Gils Marit J., Rijsdijk Linda W. E., Boeser-Nunnink Brigitte D., Heringa Jaap, Schuitemaker Hanneke, Sanders Rogier W. HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity Retrovirology 2013;10 (1) [PubMed]
• Hoorelbeke Bart, van Montfort Thijs, Xue Jie, LiWang Patricia J., Tanaka Haruo, Igarashi Yasuhiro, van Damme Els J. M., Sanders Rogier W., Balzarini Jan HIV-1 envelope trimer has similar binding characteristics for carbohydrate-binding agents as monomeric gp120 FEBS letters 2013;587 (7):860-866 [PubMed]
• Klasse Per Johan, Depetris Rafael S., Pejchal Robert, Julien Jean-Philippe, Khayat Reza, Lee Jeong Hyun, Marozsan Andre J., Cupo Albert, Cocco Nicolette, Korzun Jacob, Yasmeen Anila, Ward Andrew B., Wilson Ian A., Sanders Rogier W., Moore John P. Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein Journal of virology 2013;87 (17):9873-9885 [PubMed]
• van der Sluis Renée M., van Montfort Thijs, Centlivre Mireille, Schopman Nick C. T., Cornelissen Marion, Sanders Rogier W., Berkhout Ben, Jeeninga Rienk E., Paxton William A., Pollakis Georgios Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity Journal of virological methods 2013;187 (1):94-102 [PubMed]
• Khayat Reza, Lee Jeong Hyun, Julien Jean-Philippe, Cupo Albert, Klasse Per Johan, Sanders Rogier W., Moore John P., Wilson Ian A., Ward Andrew B. Structural Characterization of Cleaved, Soluble HIV-1 Envelope Glycoprotein Trimers Journal of virology 2013;87 (17):9865-9872 [PubMed]
• Kong Leopold, Lee Jeong Hyun, Doores Katie J., Murin Charles D., Julien Jean-Philippe, McBride Ryan, Liu Yan, Marozsan Andre, Cupo Albert, Klasse Per-Johan, Hoffenberg Simon, Caulfield Michael, King C. Richter, Hua Yuanzi, Le Khoa M., Khayat Reza, Deller Marc C., Clayton Thomas, Tien Henry, Feizi Ten, Sanders Rogier W., Paulson James C., Moore John P., Stanfield Robyn L., Burton Dennis R., Ward Andrew B., Wilson Ian A. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Nature structural & molecular biology 2013;20 (7):796-+ [PubMed]

2012

• Anastassopoulou Cleo G., Ketas Thomas J., Sanders Rogier W., Klasse Per Johan, Moore John P. Effects of sequence changes in the HIV-1 gp41 fusion peptide on CCR5 inhibitor resistance Virology 2012;428 (2):86-97 [PubMed]
• Berkhout Ben, Sanders Rogier W. Gene therapy as a vaccine for HIV-1 Expert opinion on biological therapy 2012;12 (10):1315-1321 [PubMed]
• de Vries Robert P., Smit Cornelis H., de Bruin Erwin, Rigter Alan, de Vries Erik, Cornelissen Lisette A. H. M., Eggink Dirk, Chung Nancy P. Y., Moore John P., Sanders Rogier W., Hokke Cornelis H., Koopmans Marion, Rottier Peter J. M., de Haan Cornelis A. M. Glycan-Dependent Immunogenicity of Recombinant Soluble Trimeric Hemagglutinin Journal of virology 2012;86 (21):11735-11744 [PubMed]
• Chung Nancy P. Y., Matthews Katie, Klasse Per Johan, Sanders Rogier W., Moore John P. HIV-1 gp120 Impairs the Induction of B Cell Responses by TLR9-Activated Plasmacytoid Dendritic Cells Journal of immunology (Baltimore, Md. 2012;189 (11):5257-5265 [PubMed]
• Sanders Rogier W. HIV takes double hit before entry BMC biology 2012;10 (1):99 [PubMed]
• Klasse Per Johan, Sanders Rogier W., Cerutti Andrea, Moore John P. How Can HIV-Type-1-Env Immunogenicity Be Improved to Facilitate Antibody-Based Vaccine Development? AIDS research and human retroviruses 2012;28 (1):1-15 [PubMed]
• Berkhout Ben, Eggink Dirk, Sanders Rogier W. Is there a future for antiviral fusion inhibitors? Current opinion in virology 2012;2 (1):50-59 [PubMed]
• Banerjee Kaustuv, Michael Elizabeth, Eggink Dirk, van Montfort Thijs, Lasnik Amanda B., Palmer Kenneth E., Sanders Rogier W., Moore John P., Klasse Per Johan Occluding the Mannose Moieties on Human Immunodeficiency Virus Type 1 gp120 with Griffithsin Improves the Antibody Responses to Both Proteins in Mice AIDS research and human retroviruses 2012;28 (2):206-214 [PubMed]
• van Montfort Thijs, Sanders Rogier W. Optimizing cellular immunity against HIV-1 Gag and preventing suppression by HIV-1 gp120 Expert review of vaccines 2012;11 (10):1175-1177 [PubMed]
• Depetris Rafael S., Julien Jean-Philippe, Khayat Reza, Lee Jeong Hyun, Pejchal Robert, Katpally Umesh, Cocco Nicolette, Kachare Milind, Massi Evan, David Kathryn B., Cupo Albert, Marozsan Andre J., Olson William C., Ward Andrew B., Wilson Ian A., Sanders Rogier W., Moore John P. Partial Enzymatic Deglycosylation Preserves the Structure of Cleaved Recombinant HIV-1 Envelope Glycoprotein Trimers Journal of biological chemistry 2012;287 (29):24239-24254 [PubMed]
• Matthews Katie, Chung Nancy P. Y., Klasse Per Johan, Moore John P., Sanders Rogier W. Potent Induction of Antibody-Secreting B Cells by Human Dermal-Derived CD14(+) Dendritic Cells Triggered by Dual TLR Ligation Journal of immunology (Baltimore, Md. 2012;189 (12):5729-5744 [PubMed]
• Schopman Nick C. T., van Montfort Thijs, Willemsen Marcel, Knoepfel Stefanie A., Pollakis Georgios, van Kampen Antoine, Sanders Rogier W., Haasnoot Joost, Berkhout Ben Selective packaging of cellular miRNAs in HIV-1 particles Virus research 2012;169 (2):438-447 [PubMed]
• Melchers Mark, Bontjer Ilja, Tong Tommy, Chung Nancy P. Y., Klasse Per Johan, Eggink Dirk, Montefiori David C., Gentile Maurizio, Cerutti Andrea, Olson William C., Berkhout Ben, Binley James M., Moore John P., Sanders Rogier W. Targeting HIV-1 Envelope Glycoprotein Trimers to B Cells by Using APRIL Improves Antibody Responses Journal of virology 2012;86 (5):2488-2500 [PubMed]
• Berro Reem, Klasse Per Johan, Jakobsen Martin R., Gorry Paul R., Moore John P., Sanders Rogier W. V3 determinants of HIV-1 escape from the CCR5 inhibitors Maraviroc and Vicriviroc Virology 2012;427 (2):158-165 [PubMed]
• Berro Reem, Klasse Per Johan, Jakobsen Martin R., Gorry Paul R., Moore John P., Sanders Rogier W. V3 determinants of HIV-1 escape from the CCR5 inhibitors Maraviroc and Vicriviroc (vol 427, pg 158, 2012) Virology 2012;428 (1):76

2011

• van Montfort Thijs, Melchers Mark, Isik Gözde, Menis Sergey, Huang Po-Ssu, Matthews Katie, Michael Elizabeth, Berkhout Ben, Schief William R., Moore John P., Sanders Rogier W. A chimeric HIV-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF) domain induces enhanced antibody and T cell responses Journal of biological chemistry 2011;286 (25):22250-22261 [PubMed]
• Pejchal Robert, Doores Katie J., Walker Laura M., Khayat Reza, Huang Po-Ssu, Wang Sheng-Kai, Stanfield Robyn L., Julien Jean-Philippe, Ramos Alejandra, Crispin Max, Depetris Rafael, Katpally Umesh, Marozsan Andre, Cupo Albert, Maloveste Sebastien, Liu Yan, McBride Ryan, Ito Yukishige, Sanders Rogier W., Ogohara Cassandra, Paulson James C., Feizi Ten, Scanlan Christopher N., Wong Chi-Huey, Moore John P., Olson William C., Ward Andrew B., Poignard Pascal, Schief William R., Burton Dennis R., Wilson Ian A. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield Science 2011;334 (6059):1097-1103 [PubMed]
• Melchers Mark, Matthews Katie, de Vries Robert P., Eggink Dirk, van Montfort Thijs, Bontjer Ilja, van de Sandt Carolien, David Kathryn, Berkhout Ben, Moore John P., Sanders Rogier W. A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells Retrovirology 2011;8 (1):48 [PubMed]
• Sanders Rogier W. Clinical evaluation of a soluble trimeric HIV-1 envelope glycoprotein vaccine Expert review of vaccines 2011;10 (8):1117-1120 [PubMed]
• van Montfort Thijs, Eggink Dirk, Boot Maikel, Tuen Michael, Hioe Catarina E., Berkhout Ben, Sanders Rogier W. HIV-1 N-glycan composition governs a balance between dendritic cell-mediated viral transmission and antigen presentation Journal of immunology (Baltimore, Md. 2011;187 (9):4676-4685 [PubMed]
• Berkhout Ben, Sanders Rogier W. Molecular strategies to design an escape-proof antiviral therapy Antiviral research 2011;92 (1):7-14 [PubMed]
• Berro Reem, Klasse Per Johan, Lascano Danny, Flegler Ayanna, Nagashima Kirsten A., Sanders Rogier W., Sakmar Thomas P., Hope Thomas J., Moore John P. Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors Journal of virology 2011;85 (16):8227-8240 [PubMed]
• Eggink Dirk, Bontjer Ilja, Langedijk Johannes P. M., Berkhout Ben, Sanders Rogier W. Resistance of Human Immunodeficiency Virus Type 1 to a Third-Generation Fusion Inhibitor Requires Multiple Mutations in gp41 and Is Accompanied by a Dramatic Loss of gp41 Function Journal of virology 2011;85 (20):10785-10797 [PubMed]
• Harris Audray, Borgnia Mario J., Shi Dan, Bartesaghi Alberto, He Haifeng, Pejchal Robert, Kang Yun Kenneth, Depetris Rafael, Marozsan Andre J., Sanders Rogier W., Klasse Per Johan, Milne Jacqueline L. S., Wilson Ian A., Olson William C., Moore John P., Subramaniam Sriram Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures Proceedings of the National Academy of Sciences of the United States of America 2011;108 (28):11440-11445 [PubMed]

2010

• Eggink Dirk, Melchers Mark, Wuhrer Manfred, van Montfort Thijs, dey Antu K., Naaijkens Benno A., David Kathryn B., Le Douce Valentin, Deelder Andre M., Kang Kenneth, Olson William C., Berkhout Ben, Hokke Cornelis H., Moore John P., Sanders Rogier W. Corrigendum to: Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function (vol 401, pg 236, 2010) Virology 2010;406 (1):162-163
• Banerjee Kaustuv, Klasse P. J., Sanders Rogier W., Pereyra Florencia, Michael Elizabeth, Lu Min, Walker Bruce D., Moore John P. IgG subclass profiles in infected HIV type 1 controllers and chronic progressors and in uninfected recipients of Env vaccines AIDS research and human retroviruses 2010;26 (4):445-458 [PubMed]
• Melchers Mark Improving HIV-1 enveloppe glycoprotein vaccines 2010. 205p. ISBN 9789490371517. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Sanders R. W.)
• Eggink Dirk, Berkhout Ben, Sanders Rogier W. Inhibition of HIV-1 by Fusion Inhibitors Current pharmaceutical design 2010;16 (33):3716-3728 [PubMed]
• Eggink Dirk, Melchers Mark, Wuhrer Manfred, van Montfort Thijs, dey Antu K., Naaijkens Benno A., David Kathryn B., Le Douce Valentin, Deelder André M., Kang Kenneth, Olson William C., Berkhout Ben, Hokke Cornelis H., Moore John P., Sanders Rogier W. Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function Virology 2010;401 (2):236-247 [PubMed]
• Eggink W. D. Resistance to HIV-1 fusion inhibitors 2010. 225p. ISBN 9789490371289. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Sanders R. W.)
• Binley James M., Ban Yih-En Andrew, Crooks Emma T., Eggink Dirk, Osawa Keiko, Schief William R., Sanders Rogier W. Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization Journal of virology 2010;84 (11):5637-5655 [PubMed]
• Sanders Rogier W., Berkhout Ben Sealing the Envelope - The HIV-1 Envelope Glycoproteins as Targets for Therapeutics and Vaccines Current pharmaceutical design 2010;16 (33):3699-3700 [PubMed]
• Bontjer Ilja, Melchers Mark, Eggink Dirk, David Kathryn, Moore John P., Berkhout Ben, Sanders Rogier W. Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution Journal of biological chemistry 2010;285 (47):36456-36470 [PubMed]

2009

• Eggink Dirk, Langedijk Johannes P. M., Bonvin Alexandre M. J. J., Deng Yiqun, Lu Min, Berkhout Ben, Sanders Rogier W. Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors Journal of biological chemistry 2009;284 (39):26941-26950 [PubMed]
• Banerjee Kaustuv, Andjelic Sofija, Klasse Per Johan, Kang Yun, Sanders Rogier W., Michael Elizabeth, Durso Robert J., Ketas Thomas J., Olson William C., Moore John P. Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo Virology 2009;389 (1-2):108-121 [PubMed]
• Xu Weifeng, Santini Paul A., Sullivan John S., He Bing, Shan Meimei, Ball Susan C., Dyer Wayne B., Ketas Thomas J., Chadburn Amy, Cohen-Gould Leona, Knowles Daniel M., Chiu April, Sanders Rogier W., Chen Kang, Cerutti Andrea HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits Nature immunology 2009;10 (9):1008-1017 [PubMed]
• Stax Martijn J., van Montfort Thijs, Sprenger Richard R., Melchers Mark, Sanders Rogier W., van Leeuwen Elisabeth, Repping Sjoerd, Pollakis Georgios, Speijer Dave, Paxton William A. Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes Virology 2009;391 (2):203-211 [PubMed]
• Bontjer Ilja, Land Aafke, Eggink Dirk, Verkade Erwin, Tuin Kiki, Baldwin Chris, Pollakis Georgios, Paxton William A., Braakman Ineke, Berkhout Ben, Sanders Rogier W. Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution Journal of virology 2009;83 (1):368-383 [PubMed]
• de Jong Menno D., Sanders Rogier W. The future of influenza vaccines BMJ (Clinical research ed.) 2009;339:b4014 [PubMed]
• Berro Reem, Sanders Rogier W., Lu Min, Klasse Per J., Moore John P. Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry PLoS pathogens 2009;5 (8):e1000548 [PubMed]

2008

• Sanders Rogier W., Hsu Shang-Te D., van Anken Eelco, Liscaljet I. Marije, Dankers Martijn, Bontjer Ilja, Land Aafke, Braakman Ineke, Bonvin Alexandre M. J. J., Berkhout Ben Evolution rescues folding of human immunodeficiency virus-1 envelope glycoprotein GP120 lacking a conserved disulfide bond Molecular biology of the cell 2008;19 (11):4707-4716 [PubMed]
• van Anken Eelco, Sanders Rogier W., Liscaljet I. Marije, Land Aafke, Bontjer Ilja, Tillemans Sonja, Nabatov Alexey A., Paxton William A., Berkhout Ben, Braakman Ineke Only five of 10 strictly conserved disulfide bonds are essential for folding and eight for function of the HIV-1 envelope glycoprotein Molecular biology of the cell 2008;19 (10):4298-4309 [PubMed]
• Eggink Dirk, Baldwin Christopher E., Deng Yiqun, Langedijk Johannes P. M., Lu Min, Sanders Rogier W., Berkhout Ben Selection of T1249-resistant human immunodeficiency virus type 1 variants Journal of virology 2008;82 (13):6678-6688 [PubMed]
• Sanders Rogier W., van Anken Eelco, Nabatov Alexei A., Liscaljet I. Marije, Bontjer Ilja, Eggink Dirk, Melchers Mark, Busser Els, Dankers Martijn M., Groot Fedde, Braakman Ineke, Berkhout Ben, Paxton William A. The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion Retrovirology 2008;5:10 [PubMed]

2007

• Eggink Dirk, Melchers Mark, Sanders Rogier W. Antibodies to HIV-1: aiming at the right target Trends in microbiology 2007;15 (7):291-294 [PubMed]
• Shan Meimei, Klasse Per Johan, Banerjee Kaustuv, dey Antu K., Iyer Sai Prasad N., Dionisio Robert, Charles Dustin, Campbell-Gardener Lila, Olson William C., Sanders Rogier W., Moore John P. HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells PLoS pathogens 2007;3 (11):e169-1650 [PubMed]

2006

• Groot Fedde, Sanders Rogier W., ter Brake Olivier, Nazmi Kamran, Veerman Enno C. I., Bolscher Jan G. M., Berkhout Ben Histatin 5-derived peptide with improved fungicidal properties enhances human immunodeficiency virus type 1 replication by promoting viral entry Journal of virology 2006;80 (18):9236-9243 [PubMed]

2005

• Beddows Simon, Schülke Norbert, Kirschner Marc, Barnes Kelly, Franti Michael, Michael Elizabeth, Ketas Thomas, Sanders Rogier W., Maddon Paul J., Olson William C., Moore John P. Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1 Journal of virology 2005;79 (14):8812-8827 [PubMed]
• Groot Fedde, Geijtenbeek Teunis B. H., Sanders Rogier W., Baldwin Christopher E., Sanchez-Hernandez Marta, Floris René, van Kooyk Yvette, de Jong Esther C., Berkhout Ben Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction Journal of virology 2005;79 (5):3009-3015 [PubMed]
• Fernández Ariel, Tawfik Dan S., Berkhout Ben, Sanders Rogier, Kloczkowski Andrzej, Sen Taner, Jernigan Bob Protein promiscuity: drug resistance and native functions--HIV-1 case Journal of biomolecular structure & dynamics 2005;22 (6):615-624 [PubMed]

2004

• Baldwin Chris E., Sanders Rogier W., Deng Yiqun, Jurriaans Suzanne, Lange Joep M., Lu Min, Berkhout Ben Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor Journal of virology 2004;78 (22):12428-12437 [PubMed]
• Sanders Rogier W., Busser Els, Moore John P., Lu Min, Berkhout Ben Evolutionary repair of HIV type 1 gp41 with a kink in the N-terminal helix leads to restoration of the six-helix bundle structure AIDS research and human retroviruses 2004;20 (7):742-749 [PubMed]
• Sanders Rogier W., Dankers Martijn M., Busser Els, Caffrey Michael, Moore John P., Berkhout Ben Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41 Retrovirology 2004;1 (1):3 [PubMed]
• Sanders R. W. The HIV-1 envelope glycoproteins: folding, function and vaccine design 2004. 337p. ISBN 9789053566671. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Berkhout B., Moore J. P.)

2003

• Baldwin C. E., Sanders R. W., Berkhout B. Inhibiting HIV-1 entry with fusion inhibitors Current medicinal chemistry 2003;10 (17):1633-1642 [PubMed]

2002

• Sanders Rogier W., de Jong Esther C., Baldwin Christopher E., Schuitemaker Joost H. N., Kapsenberg Martien L., Berkhout Ben Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells Journal of virology 2002;76 (15):7812-7821 [PubMed]
• Binley James M., Sanders Rogier W., Master Aditi, Cayanan Charmagne S., Wiley Cheryl L., Schiffner Linnea, Travis Bruce, Kuhmann Shawn, Burton Dennis R., Hu Shiu-Lok, Olson William C., Moore John P. Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins Journal of virology 2002;76 (6):2606-2616 [PubMed]
• Schülke Norbert, Vesanen Mika S., Sanders Rogier W., Zhu Ping, Lu Min, Anselma Deborah J., Villa Anthony R., Parren Paul W. H. I., Binley James M., Roux Kenneth H., Maddon Paul J., Moore John P., Olson William C. Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein Journal of virology 2002;76 (15):7760-7776 [PubMed]
• Sanders Rogier W., Vesanen Mika, Schuelke Norbert, Master Aditi, Schiffner Linnea, Kalyanaraman Roopa, Paluch Maciej, Berkhout Ben, Maddon Paul J., Olson William C., Lu Min, Moore John P. Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1 Journal of virology 2002;76 (17):8875-8889 [PubMed]
• Sanders Rogier W., Venturi Miro, Schiffner Linnea, Kalyanaraman Roopa, Katinger Hermann, Lloyd Kenneth O., Kwong Peter D., Moore John P. The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120 Journal of virology 2002;76 (14):7293-7305 [PubMed]

2001

• Jeeninga R. E., Keulen W., Boucher C., Sanders R. W., Berkhout B. Evolution of AZT resistance in HIV-1: the 41-70 intermediate that is not observed in vivo has a replication defect Virology 2001;283 (2):294-305 [PubMed]

2000

• Binley J. M., Sanders R. W., Clas B., Schuelke N., Master A., Guo Y., Kajumo F., Anselma D. J., Maddon P. J., Olson W. C., Moore J. P. A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure Journal of virology 2000;74 (2):627-643 [PubMed]
• Sanders R. W., Schiffner L., Master A., Kajumo F., Guo Y., Dragic T., Moore J. P., Binley J. M. Variable-loop-deleted variants of the human immunodeficiency virus type 1 envelope glycoprotein can be stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits Journal of virology 2000;74 (11):5091-5100 [PubMed]

1999

• Verhoef K., Sanders R. W., Fontaine V., Kitajima S., Berkhout B. Evolution of the human immunodeficiency virus type 1 long terminal repeat promoter by conversion of an NF-kappaB enhancer element into a GABP binding site Journal of virology 1999;73 (2):1331-1340 [PubMed]