Prof. S.E. la Fleur PhD publications

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Publications Prof. S.E. la Fleur PhD

Positions
Associate Professor, Full Professor
Main activities
Research
Specialisation
Neurobiology of Energy Metabolism
Focus of research

Our research aims to unravel the mechanistic link between diet composition and the development of obesity and diabetes as a first step towards a better understanding of the pathogenesis of Type 2 Diabetes Mellitus, focusing on the role of the brain.

 

2020

  • Koekkoek L. L., Unmehopa U. A., Eggels L., Kool T., Lamuadni K., Diepenbroek C., Mul J. D., Serlie M. J., la Fleur S. E. A free-choice high-fat diet modulates the effects of a sucrose bolus on the expression of genes involved in glucose handling in the hypothalamus and nucleus accumbens. Physiology & behavior 2020;222 [PubMed]
  • Gumbs Myrtille C. R. Brain circuitries in control of feeding behaviors: Focus on Neuropeptide Y 2020. 282p. ISBN 9789402818789. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Booij Jan, la Fleur Susanne E.; Co-supervisor: Mul J. D.)
  • Gumbs Myrtille C. R., Eggels Leslie, Vuuregge Anna H., Unmehopa Unga A., Mul Joram D., la Fleur Susanne E. Effects of Neuropeptide Y administration into the lateral hypothalamus on intake of free-choice high-fat high-sucrose diet components of the male Wistar rat Nutritional neuroscience 2020:1-10 [PubMed]
  • Genzel Lisa, Adan Roger, Berns Anton, van den Beucken Jeroen, Blokland Arjan, Boddeke Erik H. W. G. M., Bogers Willy M., Bontrop Ronald, Bulthuis R., Bousema Teun, Clevers Hans, Coenen Tineke C. J. J., Dam Anne-Marie van, Deen Peter M. T., van Dijk K. W., Eggen Bart J. L., Elgersma Ype, Erdogan Izel, Englitz Bernard, Fentener van Vlissingen J. Martje, la Fleur Susanne, Fouchier Ron, Fitzsimons Carlos P., Frieling Wilbert, Haagmans Bart, Heesters Balthasar A., Henckens Marloes, Herfst Sander, Hol Elly, van den Hove Daniel, de Jonge Marien I., Jonkers Jos, Joosten Leo A. B., Kalsbeek Andries, Kamermans Maarten, Kampinga Harm H., Kas Martien J., Keijer J., Kersten Sander, Kiliaan Amanda J., Kooij Taco W. A., Kooijman Sander, Koopman Werner J. H., Korosi Aniko, Krugers Harm J., Kuiken Thijs, Kushner Steven A., Langermans Jan A. M., Lesscher Heidi, Lucassen Paul J., Lutgens Esther, Netea Mihai G., Noldus Lucas P. J. J., van der Meer Jos W. M., Meye Frank J., Mul Joram D., van Oers Kees, Olivier Jocelien D. A., Pasterkamp R. Jeroen, Philippens Ingrid H. C. H. M., Prickaerts Jos, Pullox Bart J. A., Rensen Patrick C. N., van Rheenen Jacco, van Rij Ronald P., Ritsma Laila, Rockx Barry.H. G., Roozendaal Benno, van Schothorst Evert M., Stittelaar K., Stockhofe Norbert, Swaab Dick F., de Swart Rik L., Vanderschuren Louk J. M. J., de Vries Taco, de Vrij Femke, van Wezel Richard, Wierenga Corette J., Wiesmann Maximilian, Willuhn Ingo, de Zeeuw Chris I., Homberg Judith R. How the COVID-19 pandemic highlights the necessity of animal research Current biology 2020;30 (18):R1014-R1018 [PubMed]
  • Hartstra Annick V., Schüppel Valentina, Imangaliyev Sultan, Schrantee Anouk, Prodan Andrei, Collard Didier, Levin Evgeni, Dallinga-Thie Geesje, Ackermans Mariette T., Winkelmeijer Maaike, Havik Stefan R., Metwaly Amira, Lagkouvardos Ilias, Nier Anika, Bergheim Ina, Heikenwalder Mathias, Dunkel Andreas, Nederveen Aart J., Liebisch Gerhard, Mancano Giulia, Claus Sandrine P., Benítez-Páez Alfonso, la Fleur Susanne E., Bergman Jacques J., Gerdes Victor, Sanz Yolanda, Booij Jan, Kemper Elles, Groen Albert K., Serlie Mireille J., Haller Dirk, Nieuwdorp Max Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome Molecular metabolism 2020;42 [PubMed]
  • Gumbs M. C. R., Eggels L., Kool T., Unmehopa U. A., van den Heuvel J. K., Lamuadni K., Mul J. D., la Fleur S. E. Neuropeptide Y Signaling in the Lateral Hypothalamus Modulates Diet Component Selection and is Dysregulated in a Model of Diet-Induced Obesity Neuroscience 2020;447:28-40 [PubMed]
  • Oosterman Johanneke E., Koekkoek Laura L., Foppen Ewout, Unmehopa Unga A., Eggels Leslie, Verheij Joanne, Fliers Eric, la Fleur Susanne E., Kalsbeek Andries Synergistic Effect of Feeding Time and Diet on Hepatic Steatosis and Gene Expression in Male Wistar Rats Obesity (Silver Spring, Md.) 2020;28 (S1):S81-S92 [PubMed]
  • Kalsbeek Martin Jt, Wolff Samantha Ec, Korpel Nikita L., la Fleur Susanne E., Romijn Johannes A., Fliers Eric, Kalsbeek Andries, Swaab Dick F., Huitinga Inge, Hol Elly M., Yi Chun-Xia The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia JCI insight 2020;5 (16) [PubMed]

2019

  • Gumbs Myrtille C. R., Vuuregge Anna H., Eggels Leslie, Unmehopa Unga A., Lamuadni Khalid, Mul Joram D., la Fleur Susanne E. Afferent neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats Journal of comparative neurology 2019;527 (16):2659-2674 [PubMed]
  • Jan Stenvers Dirk, Scheer Frank A. J. L., Schrauwen Patrick, la Fleur Susanne E., Kalsbeek Andries Circadian clocks and insulin resistance Nature reviews. Endocrinology 2019;15 (2):75-89 [PubMed]
  • Belegri Evangelia Diet-induced hypothalamic inflammation, cellular stress and the acute phase response 2019. 170p. ISBN 9789402815382. [UvA Dissertations Online] University of Amsterdam. (Supervisors: la Fleur S. E. , Fliers Eric; Co-supervisors: Boelen A. , Kalsbeek A.)
  • Milanova Irina V., Kalsbeek Martin J. T., Wang Xiao-Lan, Korpel Nikita L., Stenvers Dirk Jan, Wolff Samantha E. C., de Goede Paul, Heijboer Annemieke C., Fliers Eric, la Fleur Susanne E., Kalsbeek Andries, Yi Chun-Xia Diet-induced obesity disturbs microglial immunometabolism in a time-of-day manner Frontiers in endocrinology 2019;10 (JUN) [PubMed]
  • Rijnsburger M., Unmehopa U. A., Eggels L., Serlie M. J., La Fleur S. E. One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats Nutritional neuroscience 2019;22 (8):541-550 [PubMed]
  • Ugur Muzeyyen Opioids, palatable feeding and exercise 2019. 202p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: la Fleur Susanne E., Massotte D. , Kalsbeek Andries)
  • Slomp Margo, Belegri Evita, Blancas-Velazquez Aurea S., Diepenbroek Charlene, Eggels Leslie, Gumbs Myrtille C. R., Joshi Anil, Koekkoek Laura L., Lamuadni Khalid, Ugur Muzeyyen, Unmehopa Unga A., la Fleur Susanne E., Mul Joram D. Stressing the importance of choice: Validity of a preclinical free-choice high-caloric diet paradigm to model behavioural, physiological and molecular adaptations during human diet-induced obesity and metabolic dysfunction Journal of neuroendocrinology 2019;31 (5):e12718 [PubMed]

2018

  • Blancas-Velazquez Aurea Susana, Unmehopa Unga A., Eggels Leslie, Koekkoek Laura, Kalsbeek Andries, Mendoza Jorge, la Fleur Susanne E. A free-choice high-fat high-sugar diet alters day-night Per2 gene expression in reward-related brain areas in rats Frontiers in endocrinology 2018;9 (APR) [PubMed]
  • Rijnsburger Merel Central regulation of glucose metabolism: Effects of nutrients, serotonin and dopamine 2018. 179p. ISBN 9789462996953. [UvA Dissertations Online] University of Amsterdam. (Supervisors: La Fleur S. E., Kalsbeek A.; Co-supervisors: Serlie M. J. M., Fliers E.)
  • de Git C. G. Challenging the concepts related to leptin, the hypothalamus, and energy balance 2018. 0p. ISBN 9789039370513. [UvA Dissertations Online] Utrecht University. (Supervisors: Adan R., la Fleur S. E.)
  • van der Spek Rianne, Fliers Eric, la Fleur Susanne E., Kalsbeek Andries Daily gene expression rhythms in rat white adipose tissue do not differ between subcutaneous and intra-abdominal depots Frontiers in endocrinology 2018;9 (APR) [PubMed]
  • de Goede Paul, Sen Satish, Oosterman Johanneke E., Foppen Ewout, Jansen Remi, la Fleur Susanne E., Challet Etienne, Kalsbeek Andries Differential effects of diet composition and timing of feeding behavior on rat brown adipose tissue and skeletal muscle peripheral clocks Default journal 2018;4:24-33
  • de Git Kathy C. G., Peterse C. line, Beerens Sanne, Luijendijk Mieneke C. M., van der Plasse Geoffrey, la Fleur Susanne E., Adan Roger A. H. Is leptin resistance the cause or the consequence of diet-induced obesity? International journal of obesity (2005) 2018;42 (8):1445-1457 [PubMed]
  • Versteeg R. I., Ackermans M. T., Nederveen A. J., Fliers E., Serlie M. J., La Fleur S. E. Meal timing effects on insulin sensitivity and intrahepatic triglycerides during weight loss International journal of obesity (2005) 2018;42 (2):156-162 [PubMed]
  • Belegri Evita, Eggels Leslie, la Fleur Susanne E., Boelen Anita One-week exposure to a free-choice high-fat high-sugar diet does not interfere with the lipopolysaccharide-induced acute phase response in the hypothalamus of male rats Frontiers in endocrinology 2018;9 (APR) [PubMed]
  • Blancas Velazquez Aurea S. Palatable food, clock genes and the reward circuitry 2018. ISBN 9789402810820. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Mendoza J., La Fleur S. E.; Co-supervisor: Kalsbeek A.)
  • ter Horst Kasper W., Lammers Nicolette M., Trinko Richard, Opland Darren M., Figee Martijn, Ackermans Mariette T., Booij Jan, Munckhof Pepijn van den, Schuurman P. Richard, Fliers Eric, Denys Damiaan, DiLeone Ralph J., la Fleur Susanne E., Serlie Mireille J. Striatal dopamine regulates systemic glucose metabolism in humans and mice Science translational medicine 2018;10 (442) [PubMed]
  • Belegri Evita, Eggels Leslie, Unmehopa Unga A., Mul Joram D., Boelen Anita, la Fleur Susanne E. The effects of overnight nutrient intake on hypothalamic inflammation in a free-choice diet-induced obesity rat model Appetite 2018;120:527-535 [PubMed]
  • Ursem Stan R., Vervloet Marc G., Büttler Rahel M., Ackermans Mariëtte T., Oosterwerff Mirjam M., Eekhoff Elisabeth M. V., Lips Paul, Serlie Mireille J., la Fleur Susanne E., Heijboer Annemieke C. The interrelation between FGF23 and glucose metabolism in humans Journal of diabetes and its complications 2018;32 (9):845-850 [PubMed]
  • van Galen Katy A., ter Horst Kasper W., Booij Jan, la Fleur Susanne E., Serlie Mireille J. The role of central dopamine and serotonin in human obesity: lessons learned from molecular neuroimaging studies Metabolism: clinical and experimental 2018;85:325-339 [PubMed]
  • Mul Joram D., Soto Marion, Cahill Michael E., Ryan Rebecca E., Takahashi Hirokazu, So Kawai, Zheng Jia, Croote Denise E., Hirshman Michael F., la Fleur Susanne E., Nestler Eric J., Goodyear Laurie J. Voluntary wheel running promotes resilience to chronic social defeat stress in mice: A role for nucleus accumbens ΔfosB Neuropsychopharmacology 2018;43 (9):1934-1942 [PubMed]

2017

  • Versteeg Ruth I., Stenvers Dirk J., Visintainer Dana, Linnenbank Andre, Tanck Michael W., Zwanenburg Gooitzen, Smilde Age K., Fliers Eric, Kalsbeek Andries, Serlie Mireille J., la Fleur Susanne E., Bisschop Peter H. Acute Effects of Morning Light on Plasma Glucose and Triglycerides in Healthy Men and Men with Type 2 Diabetes Journal of biological rhythms 2017;32 (2):130-142 [PubMed]
  • Rijnsburger M., Eggels L., Castel J., Cruciani-Guglielmacci C., Ackermans M. T., Luquet S., La Fleur S. E. A novel, double intra-carotid cannulation technique to study the effect of central nutrient sensing on glucose metabolism in the rat Journal of neuroscience methods 2017;290:79-84 [PubMed]
  • Versteeg Ruth I. Brain, nutrition and metabolism: Studies in lean, obese and insulin resistant humans 2017. 239p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Fliers E.; Co-supervisors: La Fleur S. E., Serlie M. J.)
  • Eggink Hannah M., Oosterman Johanneke E., de Goede Paul, de Vries Emmely M., Foppen Ewout, Koehorst Martijn, Groen Albert K., Boelen Anita, Romijn Johannes A., la Fleur Susanne E., Soeters Maarten R., Kalsbeek Andries Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats Chronobiology international 2017;34 (10):1339-1353 [PubMed]
  • Blancas-Velazquez Aurea, Mendoza Jorge, Garcia Alexandra N., la Fleur Susanne E. Diet-Induced Obesity and Circadian Disruption of Feeding Behavior Frontiers in neuroscience 2017;11:23 [PubMed]
  • Diepenbroek Charlene, Eggels Leslie, Ackermans Mariëtte T., Fliers Eric, Kalsbeek Andries, Serlie Mireille J., la Fleur Susanne E. Differential effects of hypercaloric choice diets on insulin sensitivity in rats Journal of endocrinology 2017;232 (1):49-57 [PubMed]
  • Blancas-Velazquez Aurea, la Fleur Susanne E., Mendoza Jorge Effects of a free-choice high-fathigh-sugar diet on brain PER2 and BMAL1 protein expression in mice Appetite 2017;117:263-269 [PubMed]
  • Belegri Evita, Rijnsburger Merel, Eggels Leslie, Unmehopa Unga, Scheper Wiep, Boelen Anita, la Fleur Susanne E. Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers Frontiers in neuroscience 2017;11:270 [PubMed]
  • de Vries E. M., Oosterman J. E., Eggink H. M., de Goede P., Sen S., Foppen E., Boudzovitch-Surovtseva O., Boelen A., Romijn J. A., laFleur S. E., Kalsbeek A. Effects of meal composition and meal timing on the expression of genes involved in hepatic drug metabolism in rats PLoS ONE 2017;12 (10):e0185520 [PubMed]
  • Yam K. Y., Naninck E. F. G., Abbink M. R., La Fleur S. E., Schipper L., van den Beukel J. C., Grefhorst A., Oosting A., van der Beek E. M., Lucassen P. J., Korosi A. Exposure to chronic early-life stress lastingly alters the adipose tissue, the leptin system and changes the vulnerability to western-style diet later in life in mice Psychoneuroendocrinology 2017;77:186-195 [PubMed]
  • Diepenbroek Charlene Glucose Metabolism, Diet Composition, and the Brain 2017. 221p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Fliers E., Kalsbeek A.; Co-supervisors: La Fleur S. E., Serlie M. J.)
  • Koekkoek Laura L., Mul Joram D., la Fleur Susanne E. Glucose-Sensing in the Reward System Frontiers in neuroscience 2017;11:716 [PubMed]
  • ter Horst Kasper W., Gilijamse Pim W., Versteeg Ruth I., Ackermans Mariette T., Nederveen Aart J., la Fleur Susanne E., Romijn Johannes A., Nieuwdorp Max, Zhang Dongyan, Samuel Varman T., Vatner Daniel F., Petersen Kitt F., Shulman Gerald I., Serlie Mireille J. Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans Cell reports 2017;19 (10):1997-2004 [PubMed]
  • Diepenbroek C., Rijnsburger M., Eggels L., van Megen K. M., Ackermans M. T., Fliers E., Kalsbeek A., Serlie M. J., La Fleur S. E. Infusion of fluoxetine, a serotonin reuptake inhibitor, in the shell region of the nucleus accumbens increases blood glucose concentrations in rats Neuroscience letters 2017;637:85-90 [PubMed]
  • van der Harg Judith M., Eggels Leslie, Bangel Fabian N., Ruigrok Silvie R., Zwart Rob, Hoozemans Jeroen J. M., la Fleur Susanne E., Scheper Wiep Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation Neurobiology of disease 2017;103:163-173 [PubMed]
  • Versteeg Ruth I., Koopman Karin E., Booij Jan, Ackermans Mariëtte T., Unmehopa Unga A., Fliers Eric, la Fleur Susanne E., Serlie Mireille J. Serotonin Transporter Binding in the Diencephalon Is Reduced in Insulin-Resistant Obese Humans Neuroendocrinology 2017;105 (2):141-149 [PubMed]
  • Boumans Iris J. M. M., de Boer Imke J. M., Hofstede Gert Jan, la Fleur Susanne E., Bokkers Eddie A. M. The importance of hormonal circadian rhythms in daily feeding patterns: An illustration with simulated pigs Hormones and behavior 2017;93:82-93 [PubMed]
  • Oosterman Johanneke E. The rhythm of feeding: Effect of nutrients on metabolism and the molecular clock 2017. 194p. ISBN 9789461828392. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Kalsbeek A., La Fleur S. E.; Co-supervisors: Fliers E., Belsham D. D.)
  • Versteeg Ruth I., Schrantee Anouk, Adriaanse Sofie M., Unmehopa Unga A., Booij Jan, Reneman Liesbeth, Fliers Eric, la Fleur Susanne E., Serlie Mireille J. Timing of caloric intake during weight loss differentially affects striatal dopamine transporter and thalamic serotonin transporter binding FASEB journal 2017;31 (10):4545-4554 [PubMed]

2016

  • Koopman K. E., Roefs A., Elbers D. C. E., Fliers E., Booij J., Serlie M. J., La Fleur S. E. Brain dopamine and serotonin transporter binding are associated with visual attention bias for food in lean men Psychological medicine 2016;46 (8):1707-1717 [PubMed]
  • ten Kulve Jennifer S., van Bloemendaal Liselotte, Balesar Rawien, Ijzerman Richard G., Swaab Dick F., Diamant Michaela, la Fleur Susanne E., Alkemade Anneke Decreased Hypothalamic Glucagon-Like Peptide-1 Receptor Expression in Type 2 Diabetes Patients Journal of clinical endocrinology and metabolism 2016;101 (5):2122-2129 [PubMed]
  • Pandit Rahul, Omrani Azar, Luijendijk Mieneke C. M., de Vrind Véronne A. J., van Rozen Andrea J., Ophuis Ralph J. A. Oude, Garner Keith, Kallo Imre, Ghanem Alexander, Liposits Zsolt, Conzelmann Karl-Klaus, Vanderschuren Louk J. M. J., la Fleur Susanne E., Adan Roger A. H. Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward Neuropsychopharmacology 2016;41 (9):2241-2251 [PubMed]
  • Versteeg Ruth I., Stenvers Dirk J., Kalsbeek Andries, Bisschop Peter H., Serlie Mireille J., la Fleur Susanne E. Nutrition in the spotlight: metabolic effects of environmental light Proceedings of the Nutrition Society 2016;75 (4):451-463 [PubMed]
  • van der Zwaal Esther M., de Weijer Barbara A., van de Giessen Elsmarieke M., Janssen Ignace, Berends Frits J., van de Laar Arnold, Ackermans Mariette T., Fliers Eric, la Fleur Susanne E., Booij Jan, Serlie Mireille J. Striatal dopamine D2/3 receptor availability increases after long-term bariatric surgery-induced weight loss European neuropsychopharmacology 2016;26 (7):1190-1200 [PubMed]
  • Rijnsburger Merel, Belegri Evita, Eggels Leslie, Unmehopa Unga A., Boelen Anita, Serlie Mireille J., la Fleur Susanne E. The effect of diet interventions on hypothalamic nutrient sensing pathways in rodents Physiology & behavior 2016;162:61-68 [PubMed]
  • Gumbs Myrtille C. R., van den Heuvel José K., la Fleur Susanne E. The effect of obesogenic diets on brain Neuropeptide Y Physiology & behavior 2016;162:161-173 [PubMed]
  • ter Horst K. W., Versteeg R. I., Gilijamse P. W., Ackermans M. T., Heijboer A. C., Romijn J. A., La Fleur S. E., Trinko R., DiLeone R. J., Serlie M. J. The vitamin D metabolites 25(OH)D and 1,25(OH)2D are not related to either glucose metabolism or insulin action in obese women Diabetes & metabolism 2016;42 (6):416-423 [PubMed]

2015

  • Pandit Rahul, van der Zwaal Esther M., Luijendijk Mieneke C. M., Brans Maike A. D., van Rozen Andrea J., Oude Ophuis Ralph J. A., Vanderschuren Louk J. M. J., Adan Roger A. H., la Fleur Susanne E. Central melanocortins regulate the motivation for sucrose reward PLoS ONE 2015;10 (3):e0121768 [PubMed]
  • Oosterman Johanneke E., Kalsbeek Andries, la Fleur Susanne E., Belsham Denise D. Impact of nutrients on circadian rhythmicity American journal of physiology. Regulatory, integrative and comparative physiology 2015;308 (5):R337-R350 [PubMed]
  • van den Heuvel José K., Eggels Leslie, van Rozen Andrea J., Fliers Eric, Kalsbeek Andries, Adan Roger A. H., la Fleur Susanne E. Inhibitory Effect of the Melanocortin Receptor Agonist Melanotan-II (MTII) on Feeding Depends on Dietary Fat Content and not Obesity in Rats on Free-Choice Diets Frontiers in behavioral neuroscience 2015;9:358 [PubMed]
  • Myers Kevin P., la Fleur Susanne E. Introduction to the Special Issue Physiology & behavior 2015;152 (B):v-vi [PubMed]
  • van der Harg Judith M., Eggels Leslie, Ruigrok Silvie R., Hoozemans Jeroen J. M., la Fleur Susanne E., Scheper Wiep Neuroinflammation is not a Prerequisite for Diabetes-induced Tau Phosphorylation Frontiers in neuroscience 2015;9:432 [PubMed]
  • van den Heuvel José K., Furman Kara, Gumbs Myrtille C. R., Eggels Leslie, Opland Darren M., Land Benjamin B., Kolk Sharon M., S Narayanan Nandakumar, Fliers Eric, Kalsbeek Andries, DiLeone Ralph J., la Fleur Susanne E. Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity Biological psychiatry 2015;77 (7):633-641 [PubMed]
  • Pandit Rahul Of dieting and leptin 2015. 266p. ISBN 9789039363805. [UvA Dissertations Online] Universiteit Utrecht: Faculteit Geneeskunde. (Supervisor: Adan R. A. H.; Co-supervisor: La Fleur S. E.)
  • Versteeg R. I., Serlie M. J., Kalsbeek A., La Fleur S. E. Serotonin, a possible intermediate between disturbed circadian rhythms and metabolic disease Neuroscience 2015;301:155-167 [PubMed]
  • Zaaijer Eline R., de Bruin Kora, la Fleur Susanne E., Goudriaan Anna E., van den Brink Wim, Booij Jan Subchronic administration of short-acting naltrexone has no effect on striatal dopamine transporter availability, food intake or body weight gain in rats Journal of psychopharmacology (Oxford, England) 2015;29 (3):344-348 [PubMed]
  • Kalsbeek A., Su Y., Fliers E., La Fleur S. E. The hypothalamo-pituitary-adrenal axis: circadian dysregulation and obesityin: John A. Russell, Michael J. Shipston, editors. Neuroendocrinology of Stress. S.l.: Wiley-Blackwell; 2015. p. 219-243, ISBN 9781119951704
  • Oosterman Johanneke E., Foppen Ewout, van der Spek Rianne, Fliers Eric, Kalsbeek Andries, la Fleur Susanne E. Timing of fat and liquid sugar intake alters substrate oxidation and food efficiency in male Wistar rats Chronobiology international 2015;32 (2):289-298 [PubMed]

2014

  • Boender Arjen J., Koning Nivard A., van den Heuvel José K., Luijendijk Mieneke C. M., van Rozen Andrea J., la Fleur Susanne E., Adan Roger A. H. AAV-mediated gene transfer of the obesity-associated gene Etv5 in rat midbrain does not affect energy balance or motivated behavior PLoS ONE 2014;9 (4):e94159 [PubMed]
  • Koopman Karin Eva Maria Central serotonin and dopamine transporters in overeating, obesity and insulin resistanceAmsterdam: 2014. 176p. ISBN 9789090285115. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Fliers E., Booij J.; Co-supervisors: La Fleur S. E., Serlie M. J. M.)
  • Girault Elodie M., Guigas Bruno, Alkemade Anneke, Foppen Ewout, Ackermans Mariëtte T., la Fleur Susanne E., Fliers Eric, Kalsbeek Andries Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects Naunyn-Schmiedeberg s archives of pharmacology 2014;387 (2):185-195 [PubMed]
  • Kalsbeek Andries, La Fleur Susanne, Fliers Eric Circadian control of glucose metabolism Molecular metabolism 2014;3 (4):372-383 [PubMed]
  • Borgers Anke J., Koopman Karin E., Bisschop Peter H., Serlie Mireille J., Swaab Dick F., Fliers Eric, la Fleur Susanne E., Alkemade Anneke Decreased serotonin transporter immunoreactivity in the human hypothalamic infundibular nucleus of overweight subjects Frontiers in neuroscience 2014;8:106 [PubMed]
  • van den Heuvel José K., Eggels Leslie, Fliers Eric, Kalsbeek Andries, Adan Roger A. H., la Fleur Susanne E. Differential modulation of arcuate nucleus and mesolimbic gene expression levels by central leptin in rats on short-term high-fat high-sugar diet PLoS ONE 2014;9 (1):e87729 [PubMed]
  • van Bloemendaal L., ten Kulve J. S., La Fleur S. E., Ijzerman R. G., Diamant M. Effects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS Journal of endocrinology 2014;221 (1):T1-T16 [PubMed]
  • Koopman Karin E., Caan Matthan W. A., Nederveen Aart J., Pels Anouk, Ackermans Mariette T., Fliers Eric, la Fleur Susanne E., Serlie Mireille J. Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: a randomized controlled trial Hepatology (Baltimore, Md.) 2014;60 (2):545-553 [PubMed]
  • Pandit Rahul, Luijendijk Mieneke C. M., Vanderschuren Louk J. M. J., la Fleur Susanne E., Adan Roger A. H. Limbic substrates of the effects of neuropeptide Y on intake of and motivation for palatable food Obesity (Silver Spring, Md.) 2014;22 (5):1216-1219 [PubMed]
  • van der Zwaal E. M., Janhunen S. K., La Fleur S. E., Adan R. A. H. Modelling olanzapine-induced weight gain in rats international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2014;17 (1):169-186 [PubMed]
  • van den Heuvel Johanna Klaartje Neural pathways controlling homeostatic and hedonic feeding in rats on free-choice diets 2014. 168p. ISBN 9789461824660. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Kalsbeek A., Fliers E.; Co-supervisor: La Fleur S. E.)
  • van den Heuvel J. K., Eggels L., van Rozen A. J., Luijendijk M. C. M., Fliers E., Kalsbeek A., Adan R. A. H., La Fleur S. E. Neuropeptide Y and leptin sensitivity is dependent on diet composition Journal of neuroendocrinology 2014;26 (6):377-385 [PubMed]
  • La Fleur S. E., Fliers E., Kalsbeek A. Neuroscience of glucose homeostasisin: D. W. Zochodne, R. A. Malik, editors. Handbook of Clinical Neurology, Vol. 126 (3rd series). Toronto: Elsevier; 2014. p. 341-354
  • de Weijer Barbara A., van de Giessen Elsmarieke, Janssen Ignace, Berends Frits J., van de Laar Arnold, Ackermans Mariette T., Fliers Eric, la Fleur Susanne E., Booij Jan, Serlie Mireille J. Striatal dopamine receptor binding in morbidly obese women before and after gastric bypass surgery and its relationship with insulin sensitivity Diabetologia 2014;57 (5):1078-1080 [PubMed]
  • Lammers Nicolette M., Sondermeijer Brigitte M., Twickler Th B. Marcel, de Bie Rob M., Ackermans Mariëtte T., Fliers Eric, Schuurman P. Richard, la Fleur Susanne E., Serlie Mireille J. Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson's disease Frontiers in neuroscience 2014;8:95 [PubMed]
  • la Fleur Susanne E., Serlie Mireille J. The interaction between nutrition and the brain and its consequences for body weight gain and metabolism; studies in rodents and men Best practice & research. Clinical endocrinology & metabolism 2014;28 (5):649-659 [PubMed]
  • La Fleur S. E., Luijendijk M. C. M., van der Zwaal E. M., Brans M. A. D., Adan R. A. H. The snacking rat as model of human obesity: effects of a free-choice high-fat high-sugar diet on meal patterns International journal of obesity (2005) 2014;38 (5):643-649 [PubMed]

2013

  • Diepenbroek Charlene, van der Plasse Geoffrey, Eggels Leslie, Rijnsburger Merel, Feenstra Matthijs G. P., Kalsbeek Andries, Denys Damiaan, Fliers Eric, Serlie Mireille J., la Fleur Susanne E. Alterations in blood glucose and plasma glucagon concentrations during deep brain stimulation in the shell region of the nucleus accumbens in rats Frontiers in neuroscience 2013;7:226 [PubMed]
  • Diepenbroek Charlene, Serlie Mireille J., Fliers Eric, Kalsbeek Andries, la Fleur Susanne E. Brain areas and pathways in the regulation of glucose metabolism BioFactors (Oxford, England) 2013;39 (5):505-513 [PubMed]
  • Koopman Karin Eva, Booij Jan, Fliers Eric, Serlie Mireille Johanna, la Fleur Susanne Eva Diet-induced changes in the Lean Brain: Hypercaloric high-fat-high-sugar snacking decreases serotonin transporters in the human hypothalamic region Molecular metabolism 2013;2 (4):417-422 [PubMed]
  • van der Zwaal E. M., La Fleur S. E. Genetics of Satietyin: J. Blundell, F. Bellisle, editors. Satiation, satiety and the control of food intake. S.l.: Woodhead publishing; 2013. p. 55-74, ISBN 9780857095435
  • van de Giessen E., La Fleur S. E., Eggels L., de Bruin K., van den Brink W., Booij J. High fat/carbohydrate ratio but not total energy intake induces lower striatal dopamine D2/3 receptor availability in diet-induced obesity International journal of obesity (2005) 2013;37 (5):754-757 [PubMed]
  • Girault Elodie M., Toonen Pim W., Eggels Leslie, Foppen Ewout, Ackermans Mariëtte T., la Fleur Susanne E., Fliers Eric, Kalsbeek Andries Olanzapine-induced changes in glucose metabolism are independent of the melanin-concentrating hormone system Psychoneuroendocrinology 2013;38 (11):2640-2646 [PubMed]
  • Bruinstroop Eveline, la Fleur Susanne E., Ackermans Mariette T., Foppen Ewout, Wortel Joke, Kooijman Sander, Berbée Jimmy F. P., Rensen Patrick C. N., Fliers Eric, Kalsbeek Andries The autonomic nervous system regulates postprandial hepatic lipid metabolism American journal of physiology. Endocrinology and metabolism 2013;304 (10):E1089-E1096 [PubMed]
  • Girault Elodie M. The role of hypothalamic pathways in the metabolic side effects of Olanzapine 2013. 156p. ISBN 9789088917352. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Kalsbeek A., Fliers E.; Co-supervisor: La Fleur S. E.)
  • Pandit R., La Fleur S. E., Adan R. A. H. The role of melanocortins and Neuropeptide Y in food reward European journal of pharmacology 2013;719 (1-3):208-214 [PubMed]
  • Stenvers Dirk Jan, DeVries J. Hans, la Fleur Susanne E. What's the Time? Does the Artificial Pancreas Need to Know? Diabetes 2013;62 (7):2173-2174 [PubMed]

2012

  • Alkemade Anneke, Yi Chun-Xia, Pei Lei, Harakalova Magdalena, Swaab Dick F., la Fleur Susanne E., Fliers Eric, Kalsbeek Andries AgRP and NPY Expression in the Human Hypothalamic Infundibular Nucleus Correlate with Body Mass Index, Whereas Changes in alpha MSH Are Related to Type 2 Diabetes Journal of clinical endocrinology and metabolism 2012;97 (6):E925-E933 [PubMed]
  • Koopman Karin E., la Fleur Susanne E., Fliers Eric, Serlie Mireille J., Booij Jan Assessing the Optimal Time Point for the Measurement of Extrastriatal Serotonin Transporter Binding with I-123-FP-CIT SPECT in Healthy, Male Subjects Journal of nuclear medicine 2012;53 (7):1087-1090 [PubMed]
  • La Fleur S. E., Kalsbeek A. Chapter 7: Increased Risk of Diabetes due to Obesity: Does Chronodisruption Play a Role?in: M. Garaulet, J. Ordovas, editors. Chronobiology and Obesity. New York: Springer New York; 2012. p. 111-131, ISBN 9781461450825; 9781461450818
  • Pandit Rahul, Mercer Julian G., Overduin Joost, la Fleur Susanne E., Adan Roger A. H. Dietary Factors Affect Food Reward and Motivation to Eat Obesity facts 2012;5 (2):221-242 [PubMed]
  • La Fleur S. E., Kalsbeek A. Does Chronodisruption Play a Role?in: M. Garaulet, J. Ordovas, editors. Chronobiology and Obesity. New York: Springer New York; 2012. p. 111-131, ISBN 9781461450825; 9781461450818
  • van de Giessen Elsmarieke, la Fleur Susanne E., de Bruin Kora, van den Brink Wim, Booij Jan Free-Choice and No-Choice High-Fat Diets Affect Striatal Dopamine D-2/3 Receptor Availability, Caloric Intake, and Adiposity Obesity (Silver Spring, Md.) 2012;20 (8):1738-1740 [PubMed]
  • Yi Chun-Xia, Foppen Ewout, Abplanalp William, Gao Yuanqing, Alkemade Anneke, la Fleur Susanne E., Serlie Mireille J., Fliers Eric, Buijs Ruud M., Tschöp Matthias H., Kalsbeek Andries Glucocorticoid Signaling in the Arcuate Nucleus Modulates Hepatic Insulin Sensitivity Diabetes 2012;61 (2):339-345 [PubMed]
  • van de Giessen Elsmarieke Neurobiological aspects of obesity: dopamine, srotonin, and imaging 2012. 302p. ISBN 9789461821706. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Booij J., van den Brink W.; Co-supervisors: Baas F., La Fleur S. E.)
  • van der Zwaal Esther M., Janhunen Sanna K., Luijendijk Mieneke C. M., Baclesanu Roxana, Vanderschuren Louk J. M. J., Adan Roger A. H., la Fleur Susanne E. Olanzapine and sibutramine have opposing effects on the motivation for palatable food Behavioural pharmacology 2012;23 (2):198-204 [PubMed]
  • van der Zwaal E. M., Merkestein M., Lam Y. K., Brans M. A. D., Luijendijk M. C. M., Bok L. I. H., Verheij E. R., La Fleur S. E., Adan R. A. H. The acute effects of olanzapine on ghrelin secretion, CCK sensitivity, meal size, locomotor activity and body temperature International journal of obesity (2005) 2012;36 (2):254-261 [PubMed]
  • van de Giessen Elsmarieke, de Bruin Kora, la Fleur Susanne E., van den Brink Wim, Booij Jan Triple monoamine inhibitor tesofensine decreases food intake, body weight, and striatal dopamine D2/D3 receptor availability in diet-induced obese rats European neuropsychopharmacology 2012;22 (4):290-299 [PubMed]

2011

  • La Fleur S. E., Luijendijk M. C. M., van Rozen A. J., Kalsbeek A., Adan R. A. H. A free-choice high-fat high-sugar diet induces glucose intolerance and insulin unresponsiveness to a glucose load not explained by obesity International journal of obesity (2005) 2011;35 (4):595-604 [PubMed]
  • van den Heuvel José K., van Rozen Andréa J., Adan Roger A. H., la Fleur Susanne E. An overview on how components of the melanocortin system respond to different high energy diets European journal of pharmacology 2011;660 (1):207-212 [PubMed]
  • de Backer Marijke W. A., la Fleur Susanne E., Adan Roger A. H. Both overexpression of agouti-related peptide or neuropeptide Y in the paraventricular nucleus or lateral hypothalamus induce obesity in a neuropeptide- and nucleus specific manner European journal of pharmacology 2011;660 (1):148-155 [PubMed]
  • Mul Joram D., la Fleur Susanne E., Toonen Pim W., Afrasiab-Middelman Anthonieke, Binnekade Rob, Schetters Dustin, Verheij Michel M. M., Sears Robert M., Homberg Judith R., Schoffelmeer Anton N. M., Adan Roger A. H., DiLeone Ralph J., de Vries Taco J., Cuppen Edwin Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat PLoS ONE 2011;6 (5):e19600 [PubMed]
  • Kalsbeek Andries, Scheer Frank A., Perreau-Lenz Stephanie, la Fleur Susanne E., Yi Chun-Xia, Fliers Eric, Buijs Ruud M. Circadian disruption and SCN control of energy metabolism FEBS letters 2011;585 (10):1412-1426 [PubMed]
  • Kalsbeek Andries, Chun-Xia Yi, La Fleur Susanne, Fliers Eric De rol van de biologische klok en het autonome zenuwstelsel bij wakker worden Neuropraxis 2011;15:159-171
  • Janhunen Sanna K., van der Zwaal Esther M., la Fleur Susanne E., Adan Roger A. H. Inverse agonism at α2A adrenoceptors augments the hypophagic effect of sibutramine in rats Obesity (Silver Spring, Md.) 2011;19 (10):1979-1986 [PubMed]
  • van der Zwaal E. M. Lessons learned from developing animal modelsUtrecht: 2011. [UvA Dissertations Online] Universiteit Utrecht: Faculteit Geneeskunde. (Supervisor: Adan R. A. H.; Co-supervisor: La Fleur S. E.)
  • Kalsbeek Andries, Yi Chun-Xia, Cailotto Cathy, la Fleur Susanne E., Fliers Eric, Buijs Ruud M. Mammalian clock output mechanisms Essays in biochemistry 2011;49 (1):137-151 [PubMed]
  • de Backer M. W. A., La Fleur S. E., Brans M. A. D., van Rozen A. J., Luijendijk M. C. M., Merkestein M., Garner K. M., van der Zwaal E. M., Adan R. A. H. Melanocortin receptor-mediated effects on obesity are distributed over specific hypothalamic regions International journal of obesity (2005) 2011;35 (5):629-641 [PubMed]
  • Serlie M. J., La Fleur S. E., Fliers E. Obesity: is evolution to blame? Netherlands journal of medicine 2011;69 (4):156-158 [PubMed]

2010

  • La Fleur S. E., van Rozen A. J., Luijendijk M. C. M., Groeneweg F., Adan R. A. H. A free-choice high-fat high-sugar diet induces changes in arcuate neuropeptide expression that support hyperphagia International journal of obesity (2005) 2010;34 (3):537-546 [PubMed]
  • Kalsbeek A., Bruinstroop E., Yi C. X., Klieverik L. P., La Fleur S. E., Fliers E. Hypothalamic control of energy metabolism via the autonomic nervous system Annals of the New York Academy of Sciences 2010;1212 (1):114-129 [PubMed]
  • van der Zwaal Esther M., Luijendijk Mieneke C. M., Evers Simon S., la Fleur Susanne E., Adan Roger A. H. Olanzapine affects locomotor activity and meal size in male rats Pharmacology, biochemistry, and behavior 2010;97 (1):130-137 [PubMed]
  • Mul Joram D., Yi Chun-Xia, van den Berg Sjoerd A. A., Ruiter Marieke, Toonen Pim W., van der Elst Martine C. J., Voshol Peter J., Ellenbroek Bart A., Kalsbeek Andries, la Fleur Susanne E., Cuppen Edwin Pmch expression during early development is critical for normal energy homeostasis American journal of physiology. Endocrinology and metabolism 2010;298 (3):E477-E488 [PubMed]
  • Homberg Judith R., la Fleur Susanne E., Cuppen Edwin Serotonin transporter deficiency increases abdominal fat in female, but not male rats Obesity (Silver Spring, Md.) 2010;18 (1):137-145 [PubMed]
  • de Backer M. W. A., Brans M. A. D., van Rozen A. J., van der Zwaal E. M., Luijendijk M. C. M., Garner K. G., de Krom M., van Beekum O., La Fleur S. E., Adan R. A. H. Suppressor of cytokine signaling 3 knockdown in the mediobasal hypothalamus: counterintuitive effects on energy balance Journal of molecular endocrinology 2010;45 (5):341-353 [PubMed]
  • Kalsbeek Andries, Yi Chun-Xia, la Fleur Susanne E., Buijs Ruud M., Fliers Eric SUPRACHIASMATIC NUCLEUS AND AUTONOMIC NERVOUS SYSTEM INFLUENCES ON AWAKENING FROM SLEEP International review of neurobiology 2010;93:91-107 [PubMed]
  • Kalsbeek Andries, Yi Chun-Xia, la Fleur Susanne E., Fliers Eric The hypothalamic clock and its control of glucose homeostasis Trends in endocrinology and metabolism: TEM 2010;21 (7):402-410 [PubMed]
  • Yi Chun-Xia, la Fleur Susanne E., Fliers Eric, Kalsbeek Andries The role of the autonomic nervous liver innervation in the control of energy metabolism BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2010;1802 (4):416-431 [PubMed]
  • Luijendijk M. C. M., Brakkee J. H., Boskovic E., van den Vosse R., Ligtvoet C. M., La Fleur S. E., van der Zwaal E. M., Adan R. A. H. Weet hoe je dier eet! Automatische registratie van voedselpatronen. Biotechniek 2010;49 (4):.

2009

  • de Krom Mariken, Bauer Florianne, Collier David, Adan R. A. H., la Fleur Susanne E. Genetic variation and effects on human eating behavior Annual review of nutrition 2009;29:283-304 [PubMed]
  • Tiesjema Birgitte, la Fleur Susanne E., Luijendijk Mieneke C. M., Adan Roger A. H. Sustained NPY overexpression in the PVN results in obesity via temporarily increasing food intake Obesity (Silver Spring, Md.) 2009;17 (7):1448-1450 [PubMed]

2008

  • Adan Roger A. H., Vanderschuren Louk J. M. J., la Fleur Susanne E. Anti-obesity drugs and neural circuits of feeding Trends in pharmacological sciences 2008;29 (4):208-217 [PubMed]
  • van der Zwaal Esther M., Luijendijk Mieneke C. M., Adan Roger A. H., la Fleur Susanne E. Olanzapine-induced weight gain: chronic infusion using osmotic minipumps does not result in stable plasma levels due to degradation of olanzapine in solution European journal of pharmacology 2008;585 (1):130-136 [PubMed]

2007

  • La Fleur S. E., Vanderschuren L. J. M. J., Luijendijk M. C., Kloeze B. M., Tiesjema B., Adan R. A. H. A reciprocal interaction between food-motivated behavior and diet-induced obesity International journal of obesity (2005) 2007;31 (8):1286-1294 [PubMed]
  • Tiesjema Birgitte, Adan Roger A. H., Luijendijk Mieneke C. M., Kalsbeek Andries, la Fleur Susanne E. Differential effects of recombinant adeno-associated virus-mediated neuropeptide Y overexpression in the hypothalamic paraventricular nucleus and lateral hypothalamus on feeding behavior Journal of neuroscience 2007;27 (51):14139-14146 [PubMed]
  • Dallman Mary F., Akana Susan F., Pecoraro Norman C., Warne James P., la Fleur Susanne E., Foster Michelle T. Glucocorticoids, the etiology of obesity and the metabolic syndrome Current Alzheimer research 2007;4 (2):199-204 [PubMed]
  • Tiesjema Birgitte, la Fleur Susanne E., Luijendijk Mieneke C. M., Brans Maike A. D., Lin En-Ju D., During Matthew J., Adan Roger A. Viral mediated neuropeptide Y expression in the rat paraventricular nucleus results in obesity Obesity (Silver Spring, Md.) 2007;15 (10):2424-2435 [PubMed]

2006

  • Pecoraro Norman, Ginsberg Abigail B., Warne James P., Gomez Francisca, la Fleur Susanne E., Dallman Mary F. Diverse basal and stress-related phenotypes of Sprague Dawley rats from three vendors Physiology & behavior 2006;89 (4):598-610 [PubMed]
  • Pecoraro Norman, Dallman Mary F., Warne James P., Ginsberg Abigail B., Laugero Kevin D., la Fleur Susanne E., Houshyar Hani, Gomez Francisca, Bhargava Aditi, Akana Susan F. From Malthus to motive: how the HPA axis engineers the phenotype, yoking needs to wants Progress in neurobiology 2006;79 (5-6):247-340 [PubMed]
  • Dallman Mary F., Pecoraro Norman C., la Fleur Susanne E., Warne James P., Ginsberg Abigail B., Akana Susan F., Laugero Kevin C., Houshyar Hani, Strack Alison M., Bhatnagar Seema, Bell Mary E. Glucocorticoids, chronic stress, and obesity Progress in brain research 2006;153:75-105 [PubMed]
  • Kalsbeek A., Palm I. F., La Fleur S. E., Scheer F. A. J. L., Perreau-Lenz S., Ruiter M., Kreier F., Cailotto C., Buijs R. M. SCN outputs and the hypothalamic balance of life Journal of biological rhythms 2006;21 (6):458-469 [PubMed]
  • la Fleur Susanne E. The effects of glucocorticoids on feeding behavior in rats Physiology & behavior 2006;89 (1):110-114 [PubMed]
  • Kalsbeek A., Ruiter M., La Fleur S. E., Cailotto C., Kreier F., Buijs R. M. The hypothalamic clock and its control of glucose homeostasis Progress in brain research 2006;153:283-307 [PubMed]
  • Adan R. A. H., Tiesjema B., Hillebrand J. J. G., La Fleur S. E., Kas M. J. H., de Krom M. The MC4 receptor and control of appetite British journal of pharmacology 2006;149 (7):815-827 [PubMed]

2005

  • la Fleur Susanne E., Houshyar Hani, Roy Monica, Dallman Mary F. Choice of lard, but not total lard calories, damps adrenocorticotropin responses to restraint Endocrinology 2005;146 (5):2193-2199 [PubMed]
  • Dallman Mary F., Pecoraro Norman C., la Fleur Susanne E. Chronic stress and comfort foods: self-medication and abdominal obesity Brain, behavior, and immunity 2005;19 (4):275-280 [PubMed]
  • Gomez Francisca, la Fleur Susanne E., Weiner Richard I., Dallman Mary F., El Majdoubi Mohammed Decreased gonadotropin-releasing hormone neuronal activity is associated with decreased fertility and dysregulation of food intake in the female GPR-4 transgenic rat Endocrinology 2005;146 (9):3800-3808 [PubMed]
  • la Fleur Susanne E., Manalo Sotara L., Roy Monica, Houshyar Hani, Dallman Mary F. Hepatic vagotomy alters limbic and hypothalamic neuropeptide responses to insulin-dependent diabetes and voluntary lard ingestion European journal of neuroscience 2005;21 (10):2733-2742 [PubMed]
  • la Fleur Susanne E., Wick Elizabeth C., Idumalla Prema S., Grady Eileen F., Bhargava Aditi Role of peripheral corticotropin-releasing factor and urocortin II in intestinal inflammation and motility in terminal ileum Proceedings of the National Academy of Sciences of the United States of America 2005;102 (21):7647-7652 [PubMed]
  • Pecoraro Norman, Gomez Francisca, La Fleur Susanne, Roy Monica, Dallman Mary F. Single, but not multiple pairings of sucrose and corticosterone enhance memory for sucrose drinking and amplify remote reward relativity effects Neurobiology of learning and memory 2005;83 (3):188-195 [PubMed]
  • Cailotto Cathy, la Fleur Susanne E., van Heijningen Caroline, Wortel Joke, Kalsbeek Andries, Feenstra Matthijs, Pévet Paul, Buijs Ruud M. The suprachiasmatic nucleus controls the daily variation of plasma glucose via the autonomic output to the liver: are the clock genes involved? European journal of neuroscience 2005;22 (10):2531-2540 [PubMed]

2004

  • Dallman M. F., Akana S. F., Strack A. M., Scribner K. S., Pecoraro N., La Fleur S. E., Houshyar H., Gomez F. Chronic stress-induced effects of corticosterone on brain: direct and indirect Annals of the New York Academy of Sciences 2004;1018:141-150 [PubMed]
  • la Fleur Susanne E., Akana Susan F., Manalo Sotara L., Dallman Mary F. Interaction between corticosterone and insulin in obesity: regulation of lard intake and fat stores Endocrinology 2004;145 (5):2174-2185 [PubMed]
  • Dallman Mary F., la Fleur Susanne E., Pecoraro Norman C., Gomez Francisca, Houshyar Hani, Akana Susan F. Minireview: glucocorticoids--food intake, abdominal obesity, and wealthy nations in 2004 Endocrinology 2004;145 (6):2633-2638 [PubMed]
  • Kalsbeek Andries, La Fleur Susanne, van Heijningen Caroline, Buijs Ruud M. Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver Journal of neuroscience 2004;24 (35):7604-7613 [PubMed]

2003

  • Dallman Mary F., Pecoraro Norman, Akana Susan F., la Fleur Susanne E., Gomez Francisca, Houshyar Hani, Bell M. E., Bhatnagar Seema, Laugero Kevin D., Manalo Sotara Chronic stress and obesity: a new view of "comfort food" Proceedings of the National Academy of Sciences of the United States of America 2003;100 (20):11696-11701 [PubMed]
  • La Fleur S. E. Daily rhythms in glucose metabolism: suprachiasmatic nucleus output to peripheral tissue Journal of neuroendocrinology 2003;15 (3):315-322 [PubMed]
  • Ruiter Marieke, la Fleur Susanne E., van Heijningen Caroline, van der Vliet Jan, Kalsbeek Andries, Buijs Ruud M. The daily rhythm in plasma glucagon concentrations in the rat is modulated by the biological clock and by feeding behavior Diabetes 2003;52 (7):1709-1715 [PubMed]
  • Kalsbeek A., Ruiter M., La Fleur S. E., van Heijningen C., Buijs R. M. The diurnal modulation of hormonal responses in the rat varies with different stimuli Journal of neuroendocrinology 2003;15 (12):1144-1155 [PubMed]
  • la Fleur Susanne E., Ji Hong, Manalo Sotara L., Friedman Mark I., Dallman Mary F. The hepatic vagus mediates fat-induced inhibition of diabetic hyperphagia Diabetes 2003;52 (9):2321-2330 [PubMed]
  • Buijs Ruud M., la Fleur Susanne E., Wortel Joke, van Heyningen Caroline, Zuiddam Laura, Mettenleiter Thomas C., Kalsbeek Andries, Nagai Katsuya, Niijima Akira The Suprachiasmatic nucleus balances sympathetic and parasympathetic output to peripheral organs through separate preautonomic neurons Journal of comparative neurology 2003;464 (1):36-48 [PubMed]

2001

  • La Fleur S. E., Kalsbeek A., Wortel J., Fekkes M. L., Buijs R. M. A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus Diabetes 2001;50 (6):1237-1243 [PubMed]
  • La Fleur S. E., Kalsbeek A., Wortel J., van der Vliet J., Buijs R. M. Role for the pineal and melatonin in glucose homeostasis: pinealectomy increases night-time glucose concentrations Journal of neuroendocrinology 2001;13 (12):1025-1032 [PubMed]
  • Kalsbeek A., Fliers E., Romijn J. A., La Fleur S. E., Wortel J., Bakker O., Endert E., Buijs R. M. The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels Endocrinology 2001;142 (6):2677-2685 [PubMed]

2000

  • La Fleur S. E., Kalsbeek A., Wortel J., Buijs R. M. Polysynaptic neural pathways between the hypothalamus, including the suprachiasmatic nucleus, and the liver Brain research 2000;871 (1):50-56 [PubMed]

1999

  • La Fleur S. E., Kalsbeek A., Wortel J., Buijs R. M. A suprachiasmatic nucleus generated rhythm in basal glucose concentrations Journal of neuroendocrinology 1999;11 (8):643-652 [PubMed]

1998

  • Douma B. R., Korte S. M., Buwalda B., La Fleur S. E., Bohus B., Luiten P. G. Repeated blockade of mineralocorticoid receptors, but not of glucocorticoid receptors impairs food rewarded spatial learning Psychoneuroendocrinology 1998;23 (1):33-44 [PubMed]

1997

  • Neuroendocrine correlates of emotional reactivity and coping in male rats from the Roman high (RHA/Verh)- and low (RLA/Verh)-avoidance lines Behavior genetics 1997;27 (6):503-512 [PubMed]

Corona-maatregelen

We zetten ons in om ons ziekenhuis veilig te houden tijdens de coronacrisis.

Lees deze extra maatregelen goed door voordat u een van onze locaties bezoekt: