S.A.J. Zaat PhD publications

foto

S.A.J. Zaat PhD

Position
Assistant Professor
Main activities
Education, Research
Specialisation
Biomaterial-associated infections and novel antimicrobial strategies
Focus of research
Biomaterial-associated infections and novel antimicrobial strategies

Biomaterial-associated infections. Infections of biomedical devices, or “biomaterials” (catheters, prosthetic heart valves, implants), are a major and increasing problem in modern medicine, especially in view of the increase in antibiotic resistance. We have discovered that bacteria do not only colonize the medical device by biofilm-formation, but also persist in surrounding tissue, due to disturbed local immunity. Bacterial, biomaterial, and host-responses involved in the pathogenesis are subject of studies, in order to find novel approaches for treatment and prevention. In the NANTICO (Non-adherent ANTImicrobial Coatings) consortium project different antimicrobial coating strategies have been developed to prevent infection. In the IBIZA (Imaging of Biomaterial-associated Infection using Zebrafish Analysis) a novel model for testing new biomaterials is being developed, and in the BALI (Biofilm Alliance) EU FP7 project we develop novel Synthetic Antimicrobial Antibiofilm Peptides for controlled release coatings to prevent infection of  titanium implants.
Novel antimicrobial strategies. The increase in antibiotic resistance necessitates investigations into novel antimicrobial strategies. For this we study cationic antimicrobial proteins and peptides (AMP) and natural sources such as medical grade honey. We have identified thrombocidins as the major AMP of human blood platelets, and have designed novel SAAPs (see above) based on their structure. The mechanism of action of these SAAPs is studied in depth, and they are utilized for a variety of translational research projects. Honey has been used as an antimicrobial agent since ancient times. We have fully characterized the antimicrobial components of one medicinal honey and are investigating the components responsible for the antimicrobial activity of a large collection of monofloral honeys in order to identify novel antimicrobials, in order to provide additional solutions for the major problem of antibiotic resistance. 

2020

  • Hofstee Marloes I., Muthukrishnan Gowrishankar, Atkins Gerald J., Riool Martijn, Thompson Keith, Morgenstern Mario, Stoddart Martin J., Richards Robert G., Zaat Sebastian A. J., Moriarty Thomas F. Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods American journal of pathology 2020;190 (6):1151-1163 [PubMed]
  • Balraadjsing Payal P., de Jong Esther C., van Wamel Willem J. B., Zaat Sebastian A. J. Dendritic cells internalize staphylococcus aureus more efficiently than staphylococcus epidermidis, but do not differ in induction of antigen-specific t cell proliferation Microorganisms 2020;8 (1) [PubMed]
  • van Samkar Ganapathy, Balraadjsing Payal P. S., Hermanns Henning, Hoogendijk Irene V., Hollmann Markus W., Zaat Sebastian A. J., Stevens Markus F. Microbiological and scanning electron microscopic evaluation of epidural catheters Regional anesthesia and pain medicine 2020;45 (5):381-385 [PubMed]
  • Riool Martijn, de Breij Anna, Kwakman Paulus H. S., Schonkeren-Ravensbergen Elisabeth, de Boer Leonie, Cordfunke Robert A., Malanovic Nermina, Drijfhout Jan W., Nibbering Peter H., Zaat Sebastian A. J. Thrombocidin-1-derived antimicrobial peptide TC19 combats superficial multi-drug resistant bacterial wound infections BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2020;1862 (8) [PubMed]

2019

  • Wang Dongyun, Liu Yi, Liu Yuelian, Yan Liang, Zaat Sebastian A. J., Wismeijer Daniel, Pathak Janak L., Wu Gang A dual functional bone-defect-filling material with sequential antibacterial and osteoinductive properties for infected bone defect repair Journal of biomedical materials research. Part A 2019;107 (10):2360-2370 [PubMed]
  • Zhang Xiaolin, de Boer Leonie, Stockhammer Oliver W., Grijpma Dirk W., Spaink Herman P., Zaat Sebastian A. J. A zebrafish embryo model for in vivo visualization and intravital analysis of biomaterial-associated Staphylococcus aureus infection Journal of visualized experiments 2019;2019 (143) [PubMed]
  • Newling Melissa, Sritharan Lathees, van der Ham Alwin J., Hoepel Willianne, Fiechter Renee H., de Boer Leonie, Zaat Sebastian A. J., Bisoendial Radjesh J., Baeten Dominique L. P., Everts Bart, den Dunnen Jeroen C-Reactive protein promotes inflammation through FcγR-Induced glycolytic reprogramming of human macrophages Journal of immunology (Baltimore, Md. 2019;203 (1):225-235 [PubMed]
  • Ramstedt Madeleine, Ribeiro Isabel A. C., Bujdakova Helena, Mergulhão Filipe J. M., Jordao Luisa, Thomsen Peter, Alm Martin, Burmølle Mette, Vladkova Todorka, Can Fusun, Reches Meital, Riool Martijn, Barros Alexandre, Reis Rui L., Meaurio Emilio, Kikhney Judith, Moter Annette, Zaat Sebastian A. J., Sjollema Jelmer Evaluating Efficacy of Antimicrobial and Antifouling Materials for Urinary Tract Medical Devices: Challenges and Recommendations Macromolecular bioscience 2019;19 (5):e1800384 [PubMed]
  • van de Vijfeijken S. E. C. M., Groot C., Ubbink D. T., Vandertop W. P., Depauw P. R. A. M., Nout E., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., Hoefnagels F. W. A., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Riool M., Zaat S. A. J. Factors related to failure of autologous cranial reconstructions after decompressive craniectomy Journal of cranio-maxillo-facial surgery 2019;47 (9):1420-1425 [PubMed]
  • van de Vijfeijken Sophie E. C. M., Münker Tijmen J. A. G., de Jager Niek, Vandertop William P., Becking Alfred G., Kleverlaan Cornelis J., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J. Properties of an In Vivo Fractured Poly(Methyl Methacrylate) Cranioplasty After 15 Years World neurosurgery 2019;123:e60-e68 [PubMed]
  • Moriarty T. Fintan, Harris Llinos G., Mooney Robert A., Wenke Joseph C., Riool Martijn, Zaat Sebastian A. J., Moter Annette, Schaer Thomas P., Khanna Nina, Kuehl Richard, Alt Volker, Montali Andrea, Liu Jianfeng, Zeiter Stephan, Busscher Henk J., Grainger David W., Richards R. Geoff Recommendations for design and conduct of preclinical in vivo studies of orthopedic device-related infection Journal of orthopaedic research 2019;37 (2):271-287 [PubMed]
  • Koppen Bruce C., Mulder Patrick P. G., de Boer Leonie, Riool Martijn, Drijfhout Jan W., Zaat Sebastian A. J. Synergistic microbicidal effect of cationic antimicrobial peptides and teicoplanin against planktonic and biofilm-encased Staphylococcus aureus International journal of antimicrobial agents 2019;53 (2):143-151 [PubMed]
  • Balraadjsing Payal P., Lund Lisbeth D., Souwer Yuri, Zaat Sebastian A. J., Frøkiær Hanne, de Jong Esther C. The Nature of Antibacterial Adaptive Immune Responses against Staphylococcus aureus Is Dependent on the Growth Phase and Extracellular Peptidoglycan Infection and immunity 2019;88 (1) [PubMed]
  • van de Vijfeijken S. E. C. M., Schreurs R., Dubois L., Becking A. G., van de Vijfeijken S. E. C. M., Schreurs R., Dubois L., Becking A. G., Schreurs R., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J. The use of cranial resection templates with 3D virtual planning and PEEK patient-specific implants: A 3 year follow-up Journal of cranio-maxillo-facial surgery 2019;47 (4):542-547 [PubMed]

2018

  • Zaccaria Sabrina, van Gaal Ronald C., Riool Martijn, Zaat Sebastian A. J., Dankers Patricia Y. W. Antimicrobial peptide modification of biomaterials using supramolecular additives Journal of Polymer Science, Part A: Polymer Chemistry 2018;56 (17):1926-1934 [PubMed]
  • van de Vijfeijken Sophie E. C. M., Münker Tijmen J. A. G., Spijker Rene, Karssemakers Luc H. E., Vandertop William P., Becking Alfred G., Ubbink Dirk T., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J. Autologous Bone Is Inferior to Alloplastic Cranioplasties: Safety of Autograft and Allograft Materials for Cranioplasties, a Systematic Review World neurosurgery 2018;117:443-452.e8 [PubMed]
  • Omardien Soraya, Drijfhout Jan W., Vaz Frédéric M., Wenzel Michaela, Hamoen Leendert W., Zaat Sebastian A. J., Brul Stanley Bactericidal activity of amphipathic cationic antimicrobial peptides involves altering the membrane fluidity when interacting with the phospholipid bilayer BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2018;1860 (11):2404-2415 [PubMed]
  • Vashaghian Mahshid, Zaat Sebastianus A. J., Smit Theodoor H., Roovers Jan-Paul Biomimetic implants for pelvic floor repair Neurourology and urodynamics 2018;37 (2):566-580 [PubMed]
  • Münker T. J. A. G., van de Vijfeijken S. E. C. M., Mulder C. S., Vespasiano V., Becking A. G., Kleverlaan C. J., Becking A. G., Dubois L., Karssemakers L. H. E., Milstein D. M. J., van de Vijfeijken S. E. C. M., Depauw P. R. A. M., Hoefnagels F. W. A., Vandertop W. P., Kleverlaan C. J., Münker T. J. A. G., Maal T. J. J., Nout E., Riool M., Zaat S. A. J. Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices Journal of the mechanical behavior of biomedical materials 2018;81:168-172 [PubMed]
  • Hansen Ivo S., Krabbendam Lisette, Bernink Jochem H., Loayza-Puch Fabricio, Hoepel Willianne, van Burgsteden Johan A., Kuijper Elsa C., Buskens Christianne J., Bemelman Willem A., Zaat Sebastiaan A. J., Agami Reuven, Vidarsson Gestur, van den Brink Gijs R., de Jong Esther C., Wildenberg Manon E., Baeten Dominique L. P., Everts Bart, den Dunnen Jeroen FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming Nature communications 2018;9 (1):863 [PubMed]
  • Sjollema Jelmer, Zaat Sebastian A. J., Fontaine Veronique, Ramstedt Madeleine, Luginbuehl Reto, Thevissen Karin, Li Jiuyi, van der Mei Henny C., Busscher Henk J. In vitro methods for the evaluation of antimicrobial surface designs Acta biomaterialia 2018;70:12-24 [PubMed]
  • Zhang Xiaolin, Song Jiankang, Klymov Alexey, Zhang Yang, de Boer Leonie, Jansen John A., van den Beucken Jeroen Jjp, Yang Fang, Zaat Sebastian Aj, Leeuwenburgh Sander Cg Monitoring local delivery of vancomycin from gelatin nanospheres in zebrafish larvae International journal of nanomedicine 2018;13:5377-5394 [PubMed]
  • Zhang Xiaolin, de Boer Leonie, Heiliegers Laura, Man-Bovenkerk Sandra, Selbo P. l Kristian, Drijfhout Jan W., Høgset Anders, Zaat Sebastian A. J. Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection Journal of controlled release 2018;283:214-222 [PubMed]
  • Balraadjsing P. P. S., de Jong E. C., Grijpma D. W., Tanck M. W. T., Zaat S. A. J. Poly(trimethylene carbonate) and poly(D,L-lactic acid) modify human dendritic cell responses to staphylococci but do not affect Th1 and Th2 cell development European cells & materials 2018;35:103-116 [PubMed]
  • Omardien Soraya, Drijfhout Jan W., van Veen Henk, Schachtschabel Soraya, Riool Martijn, Hamoen Leendert W., Brul Stanley, Zaat Sebastian A. J. Synthetic antimicrobial peptides delocalize membrane bound proteins thereby inducing a cell envelope stress response BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2018;1860 (11):2416-2427 [PubMed]
  • de Breij Anna, Riool Martijn, Cordfunke Robert A., Malanovic Nermina, de Boer Leonie, Koning Roman I., Ravensbergen Elisabeth, Franken Marnix, van der Heijde Tobias, Boekema Bouke K., Kwakman Paulus H. S., Kamp Niels, El Ghalbzouri Abdelouahab, Lohner Karl, Zaat Sebastian A. J., Drijfhout Jan W., Nibbering Peter H. The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms Science translational medicine 2018;10 (423):eaan4044 [PubMed]
  • Zhang Xiaolin The zebrafish embryo as a new model for biomaterial-associated infection and novel treatment strategies 2018. 179p. ISBN 9789463751964. [UvA Dissertations Online] University of Amsterdam. (Supervisor: de Jong M. D.; Co-supervisors: Zaat S. A. J. , Grijpma D. W.)

2017

  • Riool M., Dirks A. J., Jaspers V., de Boer L., Loontjens T. J., van der Loos C. M., Florquin S., Apachitei I., Rijk L. N., Keul H. A., Zaat S. A. A chlorhexidine-releasing epoxy-based coating on titanium implants prevents Staphylococcus aureus experimental biomaterial-associated infection European cells & materials 2017;33:143-157 [PubMed]
  • Riool Martijn, de Breij Anna, Drijfhout Jan W., Nibbering Peter H., Zaat Sebastian A. J. Antimicrobial Peptides in Biomedical Device Manufacturing Frontiers in chemistry 2017;5:63 [PubMed]
  • Riool Martijn, de Breij Anna, de Boer Leonie, Kwakman Paulus H. S., Cordfunke Robert A., Cohen Or, Malanovic Nermina, Emanuel Noam, Lohner Karl, Drijfhout Jan W., Nibbering Peter H., Zaat Sebastian A. J. Controlled Release of LL-37-Derived Synthetic Antimicrobial and Anti-Biofilm Peptides SAAP-145 and SAAP-276 Prevents Experimental Biomaterial-Associated Staphylococcus aureus Infection Advanced functional materials 2017;27 (20):1606623
  • van Hengel Ingmar A. J., Riool Martijn, Fratila-Apachitei Lidy E., Witte-Bouma Janneke, Farrell Eric, Zadpoor Amir A., Zaat Sebastian A. J., Apachitei Iulian Data on the surface morphology of additively manufactured Ti-6Al-4V implants during processing by plasma electrolytic oxidation Data in brief 2017;13:385-389 [PubMed]
  • Fidan S., Muhaffel F., Riool M., Cempura G., de Boer L., Zaat S. A. J., Filemonowicz A. Czyrska-, Cimenoglu H. Fabrication of oxide layer on zirconium by micro-arc oxidation: Structural and antimicrobial characteristics Materials science and engineering. C: Materials for biological applications 2017;71:565-569 [PubMed]
  • van den Boogaard Florry E., Hofstra Jorrit J., Brands Xanthe, Levi Marcel M., Roelofs Joris J. T. H., Zaat Sebastiaan A. J., van't Veer Cornelis, van der Poll Tom, Schultz Marcus J. Nebulized Recombinant Human Tissue Factor Pathway Inhibitor Attenuates Coagulation and Exerts Modest Anti-inflammatory Effects in Rat Models of Lung Injury Journal of aerosol medicine and pulmonary drug delivery 2017;30 (2):91-99 [PubMed]
  • Riool Martijn Novel antibacterial strategies to combat biomaterial-associated infection 2017. 264p. ISBN 9789462996625. [UvA Dissertations Online] University of Amsterdam. (Supervisor: de Jong M. D.; Co-supervisor: Zaat S. A. J.)
  • van Hengel Ingmar A. J., Riool Martijn, Fratila-Apachitei Lidy E., Witte-Bouma Janneke, Farrell Eric, Zadpoor Amir A., Zaat Sebastian A. J., Apachitei Iulian Selective laser melting porous metallic implants with immobilized silver nanoparticles kill and prevent biofilm formation by methicillin-resistant Staphylococcus aureus Biomaterials 2017;140:1-15 [PubMed]
  • Hansen Ivo S., Hoepel Willianne, Zaat Sebastiaan A. J., Baeten Dominique L. P., den Dunnen Jeroen Serum IgA Immune Complexes Promote Proinflammatory Cytokine Production by Human Macrophages, Monocytes, and Kupffer Cells through FcαRI-TLR Cross-Talk Journal of immunology (Baltimore, Md. 2017;199 (12):4124-4131 [PubMed]
  • Koushyar S., Economides G., Zaat S., Jiang W., Bevan C. L., Dart D. A. The prohibitin-repressive interaction with E2F1 is rapidly inhibited by androgen signalling in prostate cancer cells Oncogenesis 2017;6 (5):e333 [PubMed]
  • Zhang Xiaolin, Stockhammer Oliver W., de Boer Leonie, Vischer Norbert O. E., Spaink Herman P., Grijpma Dirk W., Zaat Sebastian A. J. The zebrafish embryo as a model to quantify early inflammatory cell responses to biomaterials Journal of biomedical materials research. Part A 2017;105 (9):2522-2532 [PubMed]

2016

  • Omardien Soraya, Brul Stanley, Zaat Sebastian A. J. Antimicrobial Activity of Cationic Antimicrobial Peptides against Gram-Positives: Current Progress Made in Understanding the Mode of Action and the Response of Bacteria Frontiers in cell and developmental biology 2016;4:111 [PubMed]
  • Moriarty T. Fintan, Kuehl Richard, Coenye Tom, Metsemakers Willem-Jan, Morgenstern Mario, Schwarz Edward M., Riool Martijn, Zaat Sebastiaan A. J., Khana Nina, Kates Stephen L., Richards R. Geoff Orthopaedic device-related infection: current and future interventions for improved prevention and treatment EFORT Open Reviews 2016;1 (4):89-99 [PubMed]
  • de Breij A., Riool M., Kwakman P. H. S., de Boer L., Cordfunke R. A., Drijfhout J. W., Cohen O., Emanuel N., Zaat S. A. J., Nibbering P. H., Moriarty T. F. Prevention of Staphylococcus aureus biomaterial-associated infections using a polymer-lipid coating containing the antimicrobial peptide OP-145 Journal of controlled release 2016;222:1-8 [PubMed]

2015

  • Metsemakers Willem-Jan, Emanuel Noam, Cohen Or, Reichart Malka, Potapova Inga, Schmid Tanja, Segal David, Riool Martijn, Kwakman Paulus H. S., de Boer Leonie, de Breij Anna, Nibbering Peter H., Richards R. Geoff, Zaat Sebastian A. J., Moriarty T. Fintan A doxycycline-loaded polymer-lipid encapsulation matrix coating for the prevention of implant-related osteomyelitis due to doxycycline-resistant methicillin-resistant Staphylococcus aureus Journal of controlled release 2015;209:47-56 [PubMed]
  • Liu Yaou, Qin Rong, Zaat Sebastiaan A. J., Breukink Eefjan, Heger Michal Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections Journal of clinical and translational research 2015;1 (3):140-167
  • Veneman Wouter J. Developing systems for high-throughput screening of infectious diseases using zebrafish 2015. 145p. ISBN 9789462038172. [UvA Dissertations Online] Universiteit Leiden: Faculteit der Wiskunde en Natuurwetenschappen. (Supervisor: Spaink H. P.; Co-supervisors: Meijer A. H., Zaat S. A. J.)
  • Tokmaji George, Vermeulen Hester, Müller Marcella C. A., Kwakman Paulus H. S., Schultz Marcus J., Zaat Sebastian A. J. Silver-coated endotracheal tubes for prevention of ventilator-associated pneumonia in critically ill patients Cochrane database of systematic reviews (Online) 2015;2015 (8):CD009201 [PubMed]

2014

  • Cleophas Rik T. C., Riool Martijn, van Ufford H. C. Quarles, Zaat Sebastian A. J., Kruijtzer John A. W., Liskamp Rob M. J. Convenient Preparation of Bactericidal Hydrogels by Covalent Attachment of Stabilized Antimicrobial Peptides Using Thiol-ene Click Chemistry ACS MACRO LETTERS 2014;3 (5):477-480
  • Daghighi Seyedmojtaba, Sjollema Jelmer, Dijkstra Rene J. B., Jaspers Valery, Zaat Sebastiaan A. J., van der Mei Henny C., Busscher Henk J. Real-time quantification of matrix metalloproteinase and integrin αvβ3 expression during biomaterial-associated infection in a murine model European cells & materials 2014;27:26-37; discussion 37-8 [PubMed]
  • Riool Martijn, de Boer Leonie, Jaspers Valery, van der Loos Chris M., van Wamel Willem J. B., Wu Gang, Kwakman Paulus H. S., Zaat Sebastian A. J. Staphylococcus epidermidis originating from titanium implants infects surrounding tissue and immune cells Acta biomaterialia 2014;10 (12):5202-5212 [PubMed]

2013

  • Bruinsma Bote G., Post Ivo C. J. H., van Rijssen Lennart B., de Boer Leonie, Heger Michal, Zaat Sebastian A. J., van Gulik Thomas M. Antibiotic prophylaxis in (sub)normothermic organ preservation: in vitro efficacy and toxicity of cephalosporins Transplantation 2013;95 (8):1064-1069 [PubMed]
  • Hiemstra Pieter S., Zaat Sebastian A. J. Antimicrobial Peptides and Innate ImmunityBasel: Springer; 2013. ISBN 9783034805414; 9783034805407 (Progress in Inflammation Research)
  • Veneman Wouter J., Stockhammer Oliver W., de Boer Leonie, Zaat Sebastian A. J., Meijer Annemarie H., Spaink Herman P. A zebrafish high throughput screening system used for Staphylococcus epidermidis infection marker discovery BMC genomics 2013;14 (1):255 [PubMed]
  • Christensen Lise, Breiting Vibeke, Bjarnsholt Thomas, Eickhardt Steffen, Høgdall Estrid, Janssen Martin, Pallua Norbert, Zaat Sebastian A. J. Bacterial Infection as a Likely Cause of Adverse Reactions to Polyacrylamide Hydrogel Fillers in Cosmetic Surgery Clinical infectious diseases 2013;56 (10):1438-1444 [PubMed]
  • Moriarty T. Fintan, Zaat Sebastian A. J., Busscher Henk J. Biomaterials associated infection : Immunological aspects and antimicrobial strategiesNew York: Springer; 2013. ISBN 9781489993748; 9781461410300; 9781461410317
  • Grainger David W., van der Mei Henny C., Jutte Paul C., van den Dungen Jan J. A. M., Schultz Marcus J., van der Laan Bernard F. A. M., Zaat Sebastian A. J., Busscher Henk J. Critical factors in the translation of improved antimicrobial strategies for medical implants and devices Biomaterials 2013;34 (37):9237-9243 [PubMed]
  • van der Aar Angelic M. G., Picavet Daisy I., Muller Femke J., de Boer Leonie, van Capel Toni M. M., Zaat Sebastian A. J., Bos Jan D., Janssen Hans, George Thaddeus C., Kapsenberg Martien L., van Ham S. Marieke, Teunissen Marcel B. M., de Jong Esther C. Langerhans cells favor skin flora tolerance through limited presentation of bacterial antigens and induction of regulatory T cells Journal of investigative dermatology 2013;133 (5):1240-1249 [PubMed]
  • Kwakman Paul H. S., Zaat Sebastian A. J. Preventive measures against transcutaneous device infectionsin: T. Fintan Moriarty, Sebastian A. J. Zaat, Henk J. Busscher, editors. Biomaterials associated infection : Immunological aspects and antimicrobial strategies. New York: Springer; 2013. p. 229-248, ISBN 9781489993748; 9781461410300; 9781461410317
  • Arias Mauricio, Zaat Sebastian A. J., Vogel Hans J. Structure–Function Relationships of Antimicrobial Chemokinesin: Pieter S. Hiemstra, Sebastian A. J. Zaat, editors. Antimicrobial Peptides and Innate Immunity. Basel: Springer; 2013. p. 183-216, ISBN 9783034805414; 9783034805407
  • Zaat Sebastian A. J. Tissue colonization in biomaterial-associated infectionin: T. Fintan Moriarty, Sebastian A. J. Zaat, Henk J. Busscher, editors. Biomaterials associated infection : Immunological aspects and antimicrobial strategies. New York: Springer; 2013. p. 175-207, ISBN 9781489993748; 9781461410300; 9781461410317

2012

  • Kwakman Paulus H. S., Zaat Sebastian A. J. Antibacterial components of honey IUBMB life 2012;64 (1):48-55 [PubMed]
  • Busscher Henk J., van der Mei Henny C., Subbiahdoss Guruprakash, Jutte Paul C., van den Dungen Jan J. A. M., Zaat Sebastian A. J., Schultz Marcus J., Grainger David W. Biomaterial-Associated Infection: Locating the Finish Line in the Race for the Surface Science translational medicine 2012;4 (153):153rv10 [PubMed]
  • Huibregtse Inge L., Zaat Sebatian A., Kapsenberg Martien L., Sartori da Silva Maria A., Peppelenbosch Maikel P., van Deventer Sander J. H., Braat Henri Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells Gastroenterology research and practice 2012;2012:639291 [PubMed]
  • den Dunnen Jeroen, Vogelpoel Lisa T. C., Wypych Tomasz, Muller Femke J. M., de Boer Leonie, Kuijpers Taco W., Zaat Sebastiaan A. J., Kapsenberg Martien L., de Jong Esther C. IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and Fc gamma RIIa in human dendritic cells Blood 2012;120 (1):112-121 [PubMed]
  • Necula B. S., van Leeuwen J. P. T. M., Fratila-Apachitei L. E., Zaat S. A. J., Apachitei I., Duszczyk J. In vitro cytotoxicity evaluation of porous TiO2-Ag antibacterial coatings for human fetal osteoblasts Acta biomaterialia 2012;8 (11):4191-4197 [PubMed]
  • Kwakman Paulus H., Müller Marcella C., Binnekade Jan M., van den Akker Johannes P., de Borgie Corianne A., Schultz Marcus J., Zaat Sebastian A. Medical-grade honey does not reduce skin colonization at central venous catheter-insertion sites of critically ill patients: a randomized controlled trial Critical care (London, England) 2012;16 (5):R214 [PubMed]
  • Daghighi Seyedmojtaba, Sjollema Jelmer, Jaspers Valery, de Boer Leonie, Zaat Sebastian A. J., Dijkstra Rene J. B., van Dam Gooitzen M., van der Mei Henny C., Busscher Henk J. Persistence of a bioluminescent Staphylococcus aureus strain on and around degradable and non-degradable surgical meshes in a murine model Acta biomaterialia 2012;8 (11):3991-3996 [PubMed]

2011

  • Helsper J. P. F. G., Ruyter-Spira C. P., Kwakman P. H. S., Bleeker W. K., Keizer L. C. P., Bade J. B., te Velde A. A., Zaat S. A. J., Verbeek M., Creemers-Molenaar J. Accumulation of human EGF in nectar of transformed plants of Nicotiana langsdorffii x N. sanderae and transfer to honey by bees Plant biology (Stuttgart, Germany) 2011;13 (5):740-746 [PubMed]
  • Nguyen Leonard T., Kwakman Paulus H. S., Chan David I., Liu Zhihong, de Boer Leonie, Zaat Sebastian A. J., Vogel Hans J. Exploring Platelet Chemokine Antimicrobial Activity: Nuclear Magnetic Resonance Backbone Dynamics of NAP-2 and TC-1 Antimicrobial agents and chemotherapy 2011;55 (5):2074-2083 [PubMed]
  • Nguyen Leonard T., de Boer Leonie, Zaat Sebastian A. J., Vogel Hans J. Investigating the cationic side chains of the antimicrobial peptide tritrpticin: hydrogen bonding properties govern its membrane-disruptive activities BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2011;1808 (9):2297-2303 [PubMed]
  • Kwakman P. H. S., de Boer L., Ruyter-Spira C. P., Creemers-Molenaar T., Helsper J. P. F. G., Vandenbroucke-Grauls C. M. J. E., Zaat S. A. J., te Velde A. A. Medical-grade honey enriched with antimicrobial peptides has enhanced activity against antibiotic-resistant pathogens European journal of clinical microbiology & infectious diseases 2011;30 (2):251-257 [PubMed]
  • Kwakman Paulus H. S., Krijgsveld Jeroen, de Boer Leonie, Nguyen Leonard T., Boszhard Laura, Vreede Jocelyne, Dekker Henk L., Speijer Dave, Drijfhout Jan W., te Velde Anje A., Crielaard Wim, Vogel Hans J., Vandenbroucke-Grauls Christina M. J. E., Zaat Sebastian A. J. Native thrombocidin-1 and unfolded thrombocidin-1 exert antimicrobial activity via distinct structural elements Journal of biological chemistry 2011;286 (50):43506-43514 [PubMed]
  • Kwakman Paulus H. S., te Velde Anje A., de Boer Leonie, Vandenbroucke-Grauls Christina M. J. E., Zaat Sebastian A. J. Two Major Medicinal Honeys Have Different Mechanisms of Bactericidal Activity PLoS ONE 2011;6 (3):e17709 [PubMed]

2010

  • Zaat S. A. J., Broekhuizen C. A. N., Riool M. Host tissue as a niche for biomaterial-associated infection Future microbiology 2010;5 (8):1149-1151 [PubMed]
  • Kwakman Paulus H. S., te Velde Anje A., de Boer Leonie, Speijer Dave, Vandenbroucke-Grauls Christina M. J. E., Zaat Sebastian A. J. How honey kills bacteria FASEB journal 2010;24 (7):2576-2582 [PubMed]
  • Broekhuizen C. A. N., Sta M., Vandenbroucke-Grauls C. M. J. E., Zaat S. A. J. Microscopic detection of viable Staphylococcus epidermidis in peri-implant tissue in experimental biomaterial-associated infection, identified by bromodeoxyuridine incorporation Infection and immunity 2010;78 (3):954-962 [PubMed]
  • Nguyen Leonard T., Chau Johnny K., Perry Nicole A., de Boer Leonie, Zaat Sebastian A. J., Vogel Hans J. Serum Stabilities of Short Tryptophan-and Arginine-Rich Antimicrobial Peptide Analogs PLoS ONE 2010;5 (9):e12684 [PubMed]
  • Nguyen Leonard T., Chan David I., Boszhard Laura, Zaat Sebastian A. J., Vogel Hans J. Structure-function studies of chemokine-derived carboxy-terminal antimicrobial peptides BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2010;1798 (6):1062-1072 [PubMed]
  • Kwakman Paulus H. S. Thrombocidinns and honey: mechanisms of action and optimization of antimicrobial activity 2010. 150p. ISBN 9789081553513. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Vandenbroucke-Grauls C. M. J. E.; Co-supervisors: Zaat S. A. J., te Velde A. A.)
  • Kwakman P. H. S., Zaat S. A. J. Werkzame componenten nu ontrafeld: Hoe antibacteriele honing wonden heelt Pharmaceutisch Weekblad 2010;145 (43):22-23

2009

  • Broekhuizen Corine A. N. Biomaterial-associated infection. Peri-implant tissue is an important niche for Staphylococcus epidermidis survival 2009. 157p. ISBN 9789090239019. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Vandenbroucke-Grauls C. M. J. E.; Co-supervisor: Zaat S. A. J.)
  • Necula Bogdan S., Fratila-Apachitei Lidy E., Zaat Sebastian A. J., Apachitei Iulian, Duszczyk Jurek In vitro antibacterial activity of porous TiO2-Ag composite layers against methicillin-resistant Staphylococcus aureus Acta biomaterialia 2009;5 (9):3573-3580 [PubMed]
  • Hofstra Jorrit J., Cornet Alexander D., de Rooy Bart F., Vlaar Alexander P., van der Poll Tom, Levi Marcel, Zaat Sebastian A. J., Schultz Marcus J. Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats Critical care (London, England) 2009;13 (5):R145 [PubMed]
  • Broekhuizen Corine A. N., de Boer Leonie, Schipper Kim, Jones Christopher D., Quadir Shan, Feldman Robert G., Vandenbroucke-Grauls Christina M. J. E., Zaat Sebastian A. J. The influence of antibodies on Staphylococcus epidermidis adherence to polyvinylpyrrolidone-coated silicone elastomer in experimental biomaterial-associated infection in mice Biomaterials 2009;30 (32):6444-6450 [PubMed]

2008

  • Kwakman Paulus H. S., van den Akker Johannes P. C., Güçlü Ahmet, Aslami Hamid, Binnekade Jan M., de Boer Leonie, Boszhard Laura, Paulus Frederique, Middelhoek Pauline, te Velde Anje A., Vandenbroucke-Grauls Christina M. J. E., Schultz Marcus J., Zaat Sebastian A. J. Medical-grade honey kills antibiotic-resistant bacteria in vitro and eradicates skin colonization Clinical infectious diseases 2008;46 (11):1677-1682 [PubMed]
  • Broekhuizen Corine A. N., de Boer Leonie, Schipper Kim, Jones Christopher D., Quadir Shan, Vandenbroucke-Grauls Christina M. J. E., Zaat Sebastian A. J. Staphylococcus epidermidis is cleared from biomaterial implants but persists in peri-implant tissue in mice despite rifampicin/vancomycin treatment Journal of biomedical materials research. Part A 2008;85 (2):498-505 [PubMed]
  • Broekhuizen Corine A. N., Schultz Marcus J., van der Wal Allard C., Boszhard Laura, de Boer Leonie, Vandenbroucke-Grauls Christina M. J. E., Zaat Sebastian A. J. Tissue around catheters is a niche for bacteria associated with medical device infection Critical care medicine 2008;36 (8):2395-2402 [PubMed]

2007

  • Broekhuizen Corine A. N., de Boer Leonie, Schipper Kim, Jones Christopher D., Quadir Shan, Feldman Roger G., Dankert Jacob, Vandenbroucke-Grauls Christina M. J. E., Weening Jan J., Zaat Sebastian A. J. Peri-implant tissue is an important niche for Staphylococcus epidermidis in experimental biomaterial-associated infection in mice Infection and immunity 2007;75 (3):1129-1136 [PubMed]
  • van Beelen Astrid J., Zelinkova Zuzana, Taanman-Kueter Esther W., Muller Femke J., Hommes Daniel W., Zaat Sebastian A. J., Kapsenberg Martien L., de Jong Esther C. Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells Immunity 2007;27 (4):660-669 [PubMed]

2006

  • Dankert Jacob, van der Werff Janneke, Joldersma Willem, Zaat Sebastian A. J. Interleukin 1alpha increases the susceptibility of rabbits to experimental viridans streptococcal endocarditis Infection and immunity 2006;74 (2):947-952 [PubMed]
  • Kwakman Paulus H. S., te Velde Anje A., Vandenbroucke-Grauls Christina M. J. E., van Deventer Sander J. H., Zaat Sebastian A. J. Treatment and prevention of Staphylococcus epidermidis experimental biomaterial-associated infection by bactericidal peptide 2 Antimicrobial agents and chemotherapy 2006;50 (12):3977-3983 [PubMed]

2005

  • Smits Hermelijn H., Engering Anneke, van der Kleij Desiree, de Jong Esther C., Schipper Kim, van Capel Toni M. M., Zaat Bas A. J., Yazdanbakhsh Maria, Wierenga Eddy A., van Kooyk Yvette, Kapsenberg Martien L. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin Journal of allergy and clinical immunology 2005;115 (6):1260-1267 [PubMed]

2004

  • Rennen Huub J. J. M., Frielink Cathelijne, Brandt Ernst, Zaat Sebastian A. J., Boerman Otto C., Oyen Wim J. G., Corstens Frans H. M. Relationship between neutrophil-binding affinity and suitability for infection imaging: comparison of (99m)Tc-labeled NAP-2 (CXCL-7) and 3 C-terminally truncated isoforms Journal of nuclear medicine 2004;45 (7):1217-1223 [PubMed]

2002

  • van Leeuwen Willem B., Snoeijers Sandor, van der Werken-Libregts Christel, Tuip Anita, van der Zee Anneke, Egberink Diane, de Proost Monique, Bik Elisabeth, Lunter Bjorn, Kluytmans Jan, Gits Etty, van Duyn Inge, Heck Max, van der Zwaluw Kim, Wannet Wim, Noordhoek Gerda T., Mulder Sije, Renders Nicole, Boers Miranda, Zaat Sebastiaan, van der Riet Daniëlle, Kooistra Mirjam, Talens Adriaan, Dijkshoorn Lenie, van der Reyden Tanny, Veenendaal Dick, Bakker Nancy, Cookson Barry, Lynch Alisson, Witte Wolfgang, Cuny Christa, Blanc Dominique, Vernez Isabelle, Hryniewicz Waleria, Fiett Janusz, Struelens Marc, Deplano Ariane, Landegent Jim, Verbrugh Henri A., van Belkum Alex Intercenter reproducibility of binary typing for Staphylococcus aureus Journal of microbiological methods 2002;51 (1):19-28 [PubMed]

2001

  • Dorigo-Zetsma J. W., Wilbrink B., Dankert J., Zaat S. A. Mycoplasma pneumoniae P1 type 1- and type 2-specific sequences within the P1 cytadhesin gene of individual strains Infection and immunity 2001;69 (9):5612-5618 [PubMed]
  • Dankert J., Krijgsveld J., van der Werff J., Joldersma W., Zaat S. A. Platelet microbicidal activity is an important defense factor against viridans streptococcal endocarditis Journal of infectious diseases 2001;184 (5):597-605 [PubMed]

2000

  • Altered gene expression in Staphylococcus aureus upon interaction with human endothelial cells Infection and immunity 2000;68 (4):1765-1772 [PubMed]
  • Antibacterial activity of antibiotic-soaked polyvinylpyrrolidone-grafted silicon elastomer hydrocephalus shunts Journal of antimicrobial chemotherapy 2000;45 (2):221-224 [PubMed]
  • A shift from oral to blood pH is a stimulus for adaptive gene expression of Streptococcus gordonii CH1 and induces protection against oxidative stress and enhanced bacterial growth by expression of msrA Infection and immunity 2000;68 (3):1061-1068 [PubMed]
  • Boelens J. J., Dankert J., Murk J. L., Weening J. J., van der Poll T., Dingemans K. P., Koole L., Laman J. D., Zaat S. A. Biomaterial-associated persistence of Staphylococcus epidermidis in pericatheter macrophages Journal of infectious diseases 2000;181 (4):1337-1349 [PubMed]
  • Broad-host-range shuttle vectors for screening of regulated promoter activity in viridans group streptococci: isolation of a pH-regulated promoter Applied and environmental microbiology 2000;66 (2):535-542 [PubMed]
  • Combined gelatin-chondroitin sulfate hydrogels for controlled release of cationic antibacterial proteins MACROMOLECULES 2000;33 (10):3705-3713
  • Kuijpers A. J., Engbers G. H., Krijgsveld J., Zaat S. A., Dankert J., Feijen J. Cross-linking and characterisation of gelatin matrices for biomedical applications Journal of biomaterials science. Polymer edition 2000;11 (3):225-243 [PubMed]
  • Enhanced susceptibility to subcutaneous abscess formation and persistent infection around catheters is associated with sustained interleukin-1beta levels Infection and immunity 2000;68 (3):1692-1695 [PubMed]
  • Genotyping of Mycoplasma pneumoniae clinical isolates reveals eight P1 subtypes within two genomic groups Journal of clinical microbiology 2000;38 (3):965-970 [PubMed]
  • Interferon-gamma protects against biomaterial-associated Staphylococcus epidermidis infection in mice Journal of infectious diseases 2000;181 (3):1167-1171 [PubMed]
  • Boelens J. J., van der Poll T., Zaat S. A., Murk J. L., Weening J. J., Dankert J. Interleukin-1 receptor type I gene-deficient mice are less susceptible to Staphylococcus epidermidis biomaterial-associated infection than are wild-type mice Infection and immunity 2000;68 (12):6924-6931 [PubMed]
  • Kuijpers A. J., van Wachem P. B., van Luyn M. J., Brouwer L. A., Engbers G. H., Krijgsveld J., Zaat S. A., Dankert J., Feijen J. In vitro and in vivo evaluation of gelatin-chondroitin sulphate hydrogels for controlled release of antibacterial proteins Biomaterials 2000;21 (17):1763-1772 [PubMed]
  • Kuijpers A. J., van Wachem P. B., van Luyn M. J., Engbers G. H., Krijgsveld J., Zaat S. A., Dankert J., Feijen J. In vivo and in vitro release of lysozyme from cross-linked gelatin hydrogels: a model system for the delivery of antibacterial proteins from prosthetic heart valves Journal of controlled release 2000;67 (2-3):323-336 [PubMed]
  • Kuijpers A. J., van Wachem P. B., van Luyn M. J., Plantinga J. A., Engbers G. H., Krijgsveld J., Zaat S. A., Dankert J., Feijen J. In vivo compatibility and degradation of crosslinked gelatin gels incorporated in knitted Dacron Journal of biomedical materials research 2000;51 (1):136-145 [PubMed]
  • Dorigo-Zetsma J. Wendelien Molecular diagnosis and epidemiology of Mycoplasma Pneumoniae 2000. 139p. ISBN 9789090142722. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Dankert J.; Co-supervisor: Zaat S. A. J.)
  • Subcutaneous abscess formation around catheters induced by viable and nonviable Staphylococcus epidermidis as well as by small amounts of bacterial cell wall components Journal of biomedical materials research 2000;50 (4):546-556 [PubMed]
  • Schultz M. J., Speelman P., Zaat S. A., Hack C. E., van Deventer S. J., van der Poll T. The effect of pseudomonas exotoxin A on cytokine production in whole blood exposed to Pseudomonas aeruginosa FEMS immunology and medical microbiology 2000;29 (3):227-232 [PubMed]
  • Krijgsveld J., Zaat S. A., Meeldijk J., van Veelen P. A., Fang G., Poolman B., Brandt E., Ehlert J. E., Kuijpers A. J., Engbers G. H., Feijen J., Dankert J. Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines Journal of biological chemistry 2000;275 (27):20374-20381 [PubMed]

1999

  • Vriesema Aldwin J. M. Adaptive gene expression of endocarditis-causing viridans group streptococci and Staphilococcus aureus s. n.; 1999. 160p. ISBN 9789090130989. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Dankert J.; Co-supervisor: Zaat S. A. J.)
  • Kuijpers A. J., Engbers G. H. M., Feijen J., de Smedt S. C., Meyvis T. K. L., Demeester J., Krijgsveld J., Zaat S. A. J., Dankert J. Characterization of the network structure of carbodiimide cross-linked gelatin gels MACROMOLECULES 1999;32 (10):3325-3333
  • Dorigo-Zetsma J. W., Zaat S. A., Wertheim-van Dillen P. M., Spanjaard L., Rijntjes J., van Waveren G., Jensen J. S., Angulo A. F., Dankert J. Comparison of PCR, culture, and serological tests for diagnosis of Mycoplasma pneumoniae respiratory tract infection in children Journal of clinical microbiology 1999;37 (1):14-17 [PubMed]
  • Demonstration by a nested PCR for Mycoplasma pneumoniae that M. pneumoniae load in the throat is higher in patients hospitalised for M. pneumoniae infection than in non-hospitalised subjects Journal of medical microbiology 1999;48 (12):1115-1122 [PubMed]
  • Boelens Jaap Jan Host Response against Biomaterials : The Role in the Pathogenesis of Biomaterial-Associated Infections 1999. 149p. ISBN 9789090133058. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Dankert J.; Co-supervisor: Zaat S. A. J.)
  • Isolation and characterization of promoter regions from Streptococcus gordonii CH1 Current microbiology 1999;39 (6):321-0326 [PubMed]
  • Krijgsveld Jeroen Thrombocidins, microbicidal proteins of human blood platelets 1999. 157p. ISBN 9789090132143. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Dankert J., Feijen J.; Co-supervisor: Zaat S. A. J.)

1998

  • Kuijpers A. J., Engbers G. H., van Wachem P. B., Krijgsveld J., Zaat S. A., Dankert J., Feijen J. Controlled delivery of antibacterial proteins from biodegradable matrices Journal of controlled release 1998;53 (1-3):235-247 [PubMed]
  • Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood Antimicrobial agents and chemotherapy 1998;42 (7):1605-1609 [PubMed]

1997

  • Cell-adherent glucan does not protect endocarditis-causing viridans streptococci against bactericidal proteins from human blood platelets Advances in experimental medicine and biology 1997;418:709-712 [PubMed]
  • Selection system for the isolation of in vivo activated promoters from endocarditis-causing viridans streptococci Advances in experimental medicine and biology 1997;418:765-767 [PubMed]

1996

  • A simple procedure for isolation of cloning vectors and endogenous plasmids from viridans group streptococci and Staphylococcus aureus Applied and environmental microbiology 1996;62 (9):3527-3529 [PubMed]

1995

  • Dankert J., van der Werff J., Zaat S. A., Joldersma W., Klein D., Hess J. Involvement of bactericidal factors from thrombin-stimulated platelets in clearance of adherent viridans streptococci in experimental infective endocarditis Infection and immunity 1995;63 (2):663-671 [PubMed]
  • Presence of a biomaterial implant facilitates induction of experimental infective endocarditis due to streptococci and staphylococci Journal of materials science. Materials in medicine 1995;6 (12):773-778
  • Variable expression of class 1 outer membrane protein in Neisseria meningitidis is caused by variation in the spacing between the -10 and -35 regions of the promoter Journal of bacteriology 1995;177 (9):2475-2480 [PubMed]

1994

  • Construction of phoE-caa, a novel PCR- and immunologically detectable marker gene for Pseudomonas putida Applied and environmental microbiology 1994;60 (11):3965-3973 [PubMed]

1993

  • Recognition of the colicin A N-terminal epitope 1C11 in vitro and in vivo in Escherichia coli by its cognate monoclonal antibody FEMS microbiology letters 1993;109 (2-3):335-342 [PubMed]

1989

  • Analysis of the major inducers of the Rhizobium nodA promoter from Vicia sativa root exudate and their activity with different nodD genes Plant molecular biology 1989;13 (2):175-188 [PubMed]
  • The ethylene-inhibitor aminoethoxyvinylglycine restores normal nodulation by Rhizobium leguminosarum biovar. viciae on Vicia sativa subsp. nigra by suppressing the 'Thick and short roots' phenotype Planta 1989;177 (2):141-150 [PubMed]

1988

  • Flavonoids in the Rhizobium-legume symbiosis Progress in clinical and biological research 1988;280:71-76 [PubMed]
  • Zaat Sebastiaan A. J. Molecular signals in the early Rhizobium-legume interaction 1988. [UvA Dissertations Online] Leiden University. (Supervisor: Lugtenberg E. J. J.; Co-supervisor: van Brussel A. A.)
  • Zaat Sebastian A. J., Wijffelman Carel A., Mulders Ine H. M., van Brussel Anton A. N., Lugtenberg Ben J. J. Root Exudates of Various Host Plants of Rhizobium leguminosarum Contain Different Sets of Inducers of Rhizobium Nodulation Genes Plant physiology 1988;86 (4):1298-1303 [PubMed]

1987

  • Flavonoids induce Rhizobium leguminosarum to produce nodDABC gene-related factors that cause thick, short roots and root hair responses on common vetch Journal of bacteriology 1987;169 (7):3388-3391 [PubMed]
  • Zaat S. A., Wijffelman C. A., Spaink H. P., van Brussel A. A., Okker R. J., Lugtenberg B. J. Induction of the nodA promoter of Rhizobium leguminosarum Sym plasmid pRL1JI by plant flavanones and flavones Journal of bacteriology 1987;169 (1):198-204 [PubMed]

1986

  • van Brussel A. A., Zaat S. A., Cremers H. C., Wijffelman C. A., Pees E., Tak T., Lugtenberg B. J. Role of plant root exudate and Sym plasmid-localized nodulation genes in the synthesis by Rhizobium leguminosarum of Tsr factor, which causes thick and short roots on common vetch Journal of bacteriology 1986;165 (2):517-522 [PubMed]

1985

  • Bacteriocin small of fast-growing rhizobia is chloroform soluble and is not required for effective nodulation Journal of bacteriology 1985;162 (3):1079-1082 [PubMed]

Corona-maatregelen

We zetten ons in om ons ziekenhuis veilig te houden tijdens de coronacrisis.

Lees deze extra maatregelen goed door voordat u een van onze locaties bezoekt: