Publications MSc T.J. Roodsant
- Position
- PhD Candidate
- Main activities
- Research
- Specialisation
- Medical Microbiology
- Focus of research
Uncovering the zoonotic potential of Streptococcus Suis
Streptococcus suis is a gram-positive bacterium commonly found in the respiratory tract of pigs. S. suis is an emerging zoonotic pathogen and the main cause of bacterial meningitis in Thailand and Vietnam. Human infections can arise from the consumption of undercooked or raw pig products, thus apparently S. suis is able cross the intestinal epithelium of the gastrointestinal tract.
We study the translocation across human intestinal epithelium of different S. suis in an intestinal organoid model. We hope to determine which traits S. suis needs to cross the human intestinal epithelium and by which mechanism the translocation takes place.
Amsterdam UMC Research Institutes
AMC departments
All publications
2020
- Roodsant Thomas, Navis Marit, Aknouch Ikrame, Renes Ingrid B., van Elburg Ruurd M., Pajkrt Dasja, Wolthers Katja C., Schultsz Constance, van der Ark Kees C. H., Sridhar Adithya, Muncan Vanesa A Human 2D Primary Organoid-Derived Epithelial Monolayer Model to Study Host-Pathogen Interaction in the Small Intestine Frontiers in cellular and infection microbiology 2020;10 [PubMed]