Crash Course (AMC PhD Program)

Information about the course Crash Course.

Go to application form.


MD's starting out on a PhD project often find they lack knowledge of some of the basic scientific concepts needed for biomedical research or don't know whether they have the 'scientific mind set". This series of lectures serves as a crash course to help them get into this mind set. By using a critical, historic, approach (revolving around the question: "how did we come to know what we know?"), a few of the developments and concepts in physics, chemistry, biochemistry and biology will be introduced. The main objective is to foster critical thinking and enthusiasm for science.


    The course runs twice a year and consists of several lectures on Wednesday, Thursday and (as an extra option for those participants interested in metabolism, biochemistry and cell biology) Friday mornings (09.00 - 13.00 hrs). The course is organized by the AMC Department of Medical Biochemistry.

    Scheduled dates:

    • October 24 and 25, 2019.
    • April 2 and 3, 2020.



      Scientific method and the birth of science, mechanics, Newtonian physics, thermodynamics, the nature of matter.

      Basic Chemistry:
      Atomic structure, periodic table of elements, MW (Dalton), number of Avogadro, molarity, covalent link, hydrogen bridges, Van der Waals forces, acid/base, pH, oxidation/reduction, structure and function of some important compounds, spectroscopy, etc.

      Metabolism (catabolism and anabolism), nucleic acids, lipids, sugars, glycolipids, energy-rich compounds (ATP etc.), amino acids, peptide bond formation, proteins and protein structure.

      Molecular Biology:
      Central dogma, DNA, genomics, enzyme kinetics, trancriptomics, mRNA, rRNA and ribosomes, tRNA and siRNA, proteomics, post translational modifications (PTMs), regulation of enzyme activities, signal transduction, biological membranes, nucleus, ER and Golgi, mitochondria, lysosomes and peroxisomes.

      Target audience:

      AMC PhD candidates with at least some experience in the study of life science.


        The course is given in English.


        A certificate is issued. Attendance is registered.

        Study load:

        10 hours, which is comparable to 0.4 ECTS points.

        Number of participants:

        Maximum 20 per course.


        No charge for registered AMC PhD candidates and employees of the AMC or AMC Medical Research BV. Other participants are charged a fee of 250 euro.

        Course coordinator:

        Dr. D. Speijer / Dep. of Medical Biochemistry / / tel. +31 (0)20 - 566 5134.

        More information:

        From the course coordinator or AMC Graduate School / / room E2-172 / tel. +31 (0)20 - 566 4618.


        AMC Graduate School
        Tel: +31 (0)20 - 566 3108