M. Coppens MD PhD

MD PhD M. Coppens

Position

Medical Specialist

Main activities

Patient care, Research

Specialisation

Vascular Medicine with an emphasis on Thrombosis and Haemostasis/Haemophilia

Focus of research

Management of bleeding in patients treated with anticoagulation and the role of specific antidotes.

Absorption of rivaroxaban and management of patients with short bowel syndrome.

Gene Therapy in patients with severe haemophilia A or B.

Biomarkers to predict joint damage in patients with severe haemophilia

Amsterdam UMC Research Institutes

ACS - Pulmonary hypertension & thrombosis

AMC departments

Vascular Medicine

Key publications

Miesbach Wolfgang, Meijer Karina, Coppens Michiel, Kampmann Peter, Klamroth Robert, Schutgens Roger, Tangelder Marco, Castaman Giancarlo, Schwäble Joachim, Bonig Halvard, Seifried Erhard, Cattaneo Federica, Meyer Christian, Leebeek Frank W. G. Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B Blood 2018;131 (9) [PubMed]
Coppens Michiel, Weitz Jeffrey I, Eikelboom John W A Synergy of Dual Pathway Inhibition in Chronic Cardiovascular Disease Circulation research 2019;124 (3):416-425 [PubMed]
Connolly Stuart J., Milling Truman J., Eikelboom John W., Gibson C. Michael, Curnutte John T., Gold Alex, Bronson Michele D., Lu Genmin, Conley Pamela B., Verhamme Peter, Schmidt Jeannot, Middeldorp Saskia, Cohen Alexander T., Beyer-Westendorf Jan, Albaladejo Pierre, Lopez-Sendon Jose, Goodman Shelly, Leeds Janet, Wiens Brian L., Siegal Deborah M., Zotova Elena, Meeks Brandi, Nakamya Juliet, Lim W. Ting, Crowther Mark, Connolly S. C., Crowther M., Eikelboom J., Gibson M., Milling T. J., Albaladejo P., Cohen A., Lopez-Sendon J., Schmidt J., Verhamme P., Beyer-Westendorf J., Wyse D. G., Garcia D., Prins M. [=Martin H.], Nakamya J., Büller H. R., Mahaffey K., Alexander J., Demchuk A., Raskob G., Schulman S., Meeks B., Zotova E., Holadyk-Gris I., Coppens M. Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors New England journal of medicine 2016;375 (12):1131-1141 [PubMed]
Douketis James D, Spyropoulos Alex C, Duncan Joanne, Carrier Marc, Le Gal Gregoire, Tafur Alfonso J, Vanassche Thomas, Verhamme Peter, Shivakumar Sudeep, Gross Peter L, Lee Agnes Y Y, Yeo Erik, Solymoss Susan, Kassis Jeannine, Le Templier Geneviève, Kowalski Stephen, Blostein Mark, Shah Vinay, MacKay Elizabeth, Wu Cynthia, Clark Nathan P, Bates Shannon M, Spencer Frederick A, Arnaoutoglou Eleni, Coppens Michiel, Arnold Donald M, Caprini Joseph A, Li Na, Moffat Karen A, Syed Summer, Schulman Sam Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant JAMA internal medicine 2019;179 (11):1469-1478 [PubMed]
Cheung Y. Whitney, Barco Stefano, Mathôt Ron A. A., van den Dool Erik-Jan, Stroobants An K., Serlie Mireille J., Middeldorp Saskia, Coppens Michiel Pharmacokinetics of dabigatran etexilate and rivaroxaban in patients with short bowel syndrome requiring parenteral nutrition: The PDER PAN study Thrombosis research 2017;160:76-82 [PubMed]