M.A. Middelkamp Hup MD PhD

MD PhD M.A. Middelkamp Hup

Positions

Other Academic Staff, Medical Specialist

Main activities

Education, Patient care, Research

Specialisation

Dermatology; focus on Pediatric Dermatology, Atopic Dermatitis and Allergic Contact Dermatitis

Focus of research

Atopic Dermatitis (AD)

-AD in children: fillagrin mutations, skin barrier biomarkers and immunological biomarkers, related to clinical parameters and phenotype

-The role of allergic contact dermatitis in children with and without AD

-Fillagrin mutations and clinical outcome of AD

-Immunology: T cells subsets, with emphasis on IL-31 producing T cells; Cytokine profiles in transdermal fluid

Haemangiomas

- treatment of ulcerated hemangiomas

Amsterdam UMC Research Institutes

AMC departments

Dermatology

Key publications

Szegedi Krisztina, Kremer Andreas E., Kezic Sanja, Teunissen Marcel B. M., Bos Jan D., Luiten Rosalie M., Res Pieter C., Middelkamp-Hup Maritza A. Increased frequencies of IL-31-producing T cells are found in chronic atopic dermatitis skin Experimental dermatology 2012;21 (6):431-436 [PubMed]
Proudfoot L. E., Powell A. M., Ayis S., Barbarot S., Baselga Torres E., Deleuran M., Fölster-Holst R., Gelmetti C., Hernández-Martin A., Middelkamp-Hup M. A., Oranje A. P., Logan K., Perkins M., Patrizi A., Rovatti G., Schofield O., Spuls P., Svensson A., Vestergaard C., Wahlgren C.-F., Schmitt J., Flohr C. The European treatment of severe atopic eczema in children taskforce (TREAT) survey British journal of dermatology 2013;169 (4):901-909 [PubMed]
Szegedi K., Lutter R., Res P. C., Bos J. D., Luiten R. M., Kezic S., Middelkamp-Hup M. A. Cytokine profiles in interstitial fluid from chronic atopic dermatitis skin Journal of the European Academy of Dermatology and Venereology 2015;29 (11):2136-2144 [PubMed]
Roekevisch E., Leeflang M. M. G., Schram M. E., Campbell L. E., Irwin McLean W. H., Kezic S., Bos J. D., Spuls P. I., Middelkamp-Hup M. A. Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment British journal of dermatology 2017;177 (6):1745-1746 [PubMed]
Lubbes Stefanie, Rustemeyer Thomas, Sillevis Smitt Johannes H., Schuttelaar Marie Louise, Middelkamp-Hup Maritza A. Contact sensitization in Dutch children and adolescents with and without atopic dermatitis - a retrospective analysis Contact dermatitis 2017;76 (3):151-159 [PubMed]