Prof. T.J. Roseboom PhD

Prof. PhD T.J. Roseboom

Positions

Associate Professor, Full Professor

Main activities

Education, Research

Specialisation

Early Development and Health

Focus of research

Tessa Roseboom is a Professor of Early Development and Health at the Amsterdam UMC, University of Amsterdam, the Netherlands. Her work focusses on the impact of the early life environment on growth, development and health throughout life. Her studies in the Dutch famine birth cohort provided the first direct evidence in humans that maternal nutrition during gestation affected offspring´s and potentially grand-offspring’s health (www.hongerwinter.nl). She applied the lessons learned about developmental plasticity to observational and experimental studies in current pregnancies, in developed and developing settings.

She is passionate about the societal impact of her work. Consequently, she advocates for investing in a good start in life by showing how fundamentally important a good start is in achieving the SDGs. She actively contributes to translating lessons from research into policy and practice. The ultimate aim of her work is to contribute to improved human health by giving each child the best possible start in life.

Amsterdam UMC Research Institutes

AMC departments

Key publications

de Rooij Susanne R., Caan Matthan W. A., Swaab Dick F., Nederveen Aart J., Majoie Charles B., Schwab Matthias, Painter Rebecca C., Roseboom Tessa J. Prenatal famine exposure has sex-specific effects on brain size Brain 2016;139 (Part 8):2136-2142 [PubMed]
van Ewijk Reyn J. G., Painter Rebecca C., Roseboom Tessa J. Associations of prenatal exposure to Ramadan with small stature and thinness in adulthood: results from a large Indonesian population-based study American journal of epidemiology 2013;177 (8):729-736 [PubMed]
de Rooij Susanne R., van Pelt Ans M. M., Ozanne Susan E., Korver Cindy M., van Daalen Saskia K. M., Painter Rebecca C., Schwab Matthias, Viegas Marcelo H., Roseboom Tessa J. Prenatal undernutrition and leukocyte telomere length in late adulthood: the Dutch famine birth cohort study American journal of clinical nutrition 2015;102 (3):655-660 [PubMed]
Lussana Federico, de Rooij Susanne R., Veenendaal Marjolein, Razzari Cristina, Fontana Gessica, Faioni Elena M., Painter Rebecca C., Middeldorp Saskia, Cattaneo Marco, Roseboom Tessa J. Prevalence of factor V Leiden and G20210A prothrombin mutation in the Dutch Famine Birth Cohort: A possible survival advantage? Thrombosis and haemostasis 2012;108 (2):399-401 [PubMed]
Pontesilli Martina, Painter Rebecca C., Grooten Iris J., van der Post Joris A., Mol Ben Willem, Vrijkotte Tanja G. M., Repping Sjoerd, Roseboom Tessa J. Subfertility and assisted reproduction techniques are associated with poorer cardiometabolic profiles in childhood Reproductive biomedicine online 2015;30 (3):258-267 [PubMed]

All Publications

Research programmes

Prof. PhD T.J. Roseboom (Early Development and Health)

A person’s experience as a fetus affects his or her health throughout life. During the past twenty years we have studied the effects of undernutrition during gestation in a group of people born around the time of the Dutch famine. This provided the first direct evidence in humans that undernutrition during gestation increases the risk of many diseases that plague our society, such as heart disease, diabetes, airways disease, obesity, renal disease and cancer. By studying the differential effects of exposure during various stages of prenatal development, we have been able to pinpoint the first trimester as an especially vulnerable period of development for subsequent disease. Therefore research now focusses on long-term consequences of environmental changes in this period, such as those occurring in hyperemesis gravidarum (severe morning sickness) and assisted reproduction techniques as well as interventions before and during pregnancy on child growth, development and health.The ultimate aim it to learn more about how to give every child a good start in life to improve the health and wellbeing of future generations.

Theme: Public Health

Faculty
MD PhD R.C. Painter

Postdocs
PhD S.R. de Rooij
MEng M. Spaan
PhD C. van de Beek
MD MSc A.W. van Deutekom
PhD A.J.G. Wirix

Others
H. Bosch
MSc A.J.J.M. Oostvogels
MSc N.E. Simons
A.M. Teitsma-Jansen

Prof. MD PhD J.A.M. van der Post (Reproductive Health, placental disease and maternal and fetal diseases)

Current PhD Candidates