E.M.M. van Leeuwen PhD

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PhD E.M.M. van Leeuwen

Position
MD-PhD
Main activities
Patient care, Research
Specialisation
Medical Immunology, Human anti-viral T cell responses, Immunodeficiencies
Focus of research

T cell responses in human viral infections

Immunodeficiency

Key publications
  • Aan de Kerk Daan J., Jansen Machiel H., ten Berge Ineke J. M., van Leeuwen Ester M. M., Kuijpers Taco W. Identification of B cell defects using age-defined reference ranges for in vivo and in vitro B cell differentiation Journal of immunology (Baltimore, Md. 2013;190 (10):5012-5019 [PubMed]
  • de Niet A., de Bruijne J., Plat-Sinnige M. J. Tempelmans, Takkenberg R. B., van Lier R. A. W., Reesink H. W., van Leeuwen E. M. M. Upregulation of CXCR3 expression on CD8+ T cells due to the pervasive influence of chronic hepatitis B and C virus infection Human immunology 2013;74 (8):899-906 [PubMed]
  • Létourneau Sven, van Leeuwen Ester M. M., Krieg Carsten, Martin Chris, Pantaleo Giuseppe, Sprent Jonathan, Surh Charles D., Boyman Onur IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25 Proceedings of the National Academy of Sciences of the United States of America 2010;107 (5):2171-2176 [PubMed]
  • van Leeuwen Ester M. M., Sprent Jonathan, Surh Charles D. Generation and maintenance of memory CD4(+) T Cells Current opinion in immunology 2009;21 (2):167-172 [PubMed]
  • Kuijpers Taco W., van Leeuwen Ester M. M., Barendregt Barbara H., Klarenbeek Paul, Aan de Kerk Daan J., Baars Paul A., Jansen Machiel H., de Vries Niek, van Lier René A. W., van der Burg Mirjam A reversion of an IL2RG mutation in combined immunodeficiency providing competitive advantage to the majority of CD8+ T cells Haematologica 2013;98 (7):1030-1038 [PubMed]
All Publications
Research programmes

Prof. PhD T.B.H. Geijtenbeek (Dendritic cells in infection and immunity)

PhD E.M.M. van Leeuwen (Promoties)