- Tiemann Christian A., Vanlier Joep, Oosterveer Maaike H., Groen Albert K., Hilbers Peter A. J., van Riel Natal A. W. Parameter Trajectory Analysis to Identify Treatment Effects of Pharmacological Interventions PLoS computational biology 2013;9 (8):e1003166 [PubMed]
- van Riel Natal A. W. Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments Briefings in bioinformatics 2006;7 (4):364-374 [PubMed]
- Hijmans Brenda S., Tiemann Christian A., Grefhorst Aldo, Boesjes Marije, van Dijk Theo H., Tietge Uwe J. F., Kuipers Folkert, van Riel Natal A. W., Groen Albert K., Oosterveer Maaike H. A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation FASEB journal 2015;29 (4):1153-1164 [PubMed]
- Sips Fianne L. P., Nyman Elin, Adiels Martin, Hilbers Peter A. J., Strålfors Peter, van Riel Natal A. W., Cedersund Gunnar Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State PLoS ONE 2015;10 (9):e0135665 [PubMed]
- Maas Anne H., Rozendaal Yvonne J. W., van Pul Carola, Hilbers Peter A. J., Cottaar Ward J., Haak Harm R., van Riel Natal A. W. A physiology-based model describing heterogeneity in glucose metabolism: the core of the Eindhoven Diabetes Education Simulator (E-DES) Journal of diabetes science and technology (Online) 2015;9 (2):282-292 [PubMed]
Prof. dr. Natal van Riel (PhD) is Professor of Computational Modelling at the Academic Medical Center - University of Amsterdam (AMC - UvA), and is one of the AMC Principal Investigators. He was trained in system and control engineering (Electrical Engineering MSc degree in 1995). In 2000 he obtained a PhD degree in Molecular Cell Biology from Utrecht University. From 2000 to 2003 he worked at Eindhoven University of Technology (TU/e) on the application of system and control theory to understand biological processes. He initiated Systems Biology research in Eindhoven. In 2006 he joined the Dept. of Biomedical Engineering of the same university to lead the Computational Systems Biology research program. He also is Associate Professor of Systems Biology and Metabolic Diseases at TU/e. His current research focuses on metabolic network modelling, methods for model parametrization and analysis of dynamic models, and applications in Metabolic Syndrome and associated diseases such as Type 2 Diabetes.
Prof. PhD N.A.W. van Riel (Computational modelling of metabolic diseases, in particular diabetes)
The research programme applies mathematical modelling and computation to study metabolic diseases, in particular Metabolic Syndrome and co-morbidities. Systems biology approaches are developed for application in basic and clinical research.
This research group participates in the Amsterdam Diabetes Center.
Postdocs
PhD V. Yildirim
PhD Students
MSc A. Cabbia
MSc Z. Félix
MSc D. Lao Martil
MEng A.H. Maas
MSc S. O'Donovan
MEng Y.J.W. Rozendaal
MEng F.L.P. Sips
Prof. MD PhD M. Nieuwdorp (Gutmicrobiota as novel diagnostic and therapeutic targets in cardiometabolism)