Publications MSc E.M.A. Slob
- Position
- PhD Candidate
- Main activities
- Research
- Specialisation
- Pharmacogenetics in children with asthma
- Focus of research
My research focuses on pharmacogenetics in children with asthma. One of my projects is an innovative randomized controlled trial (RCT) to study a pharmacogenetic intervention in asthmatic children, named the PUFFIN (Pharmaocogenetic Use For Further treatment Improvement in childreN) trial. In close collaboration with pediatric lung physicians from the Erasmus Medical Center in Rotterdam (ErasmusMC) and the University Medical Center Groningen (UMCG) 320 asthmatic children will be included in 15 hospitals in the Netherlands. This trial studies whether precision medicine guided step-up treatment (based on genotyping of the ADRB2 gene that codes for the bèta-2 receptor) will optimise treatment outcomes for the individual patient.
Amsterdam UMC Research Institutes
AMC departments
All publications
2021
- Groot Barbara, Dedding Christine, Slob Elise, Maitland Henriette, Teunissen Truus, Rutjes Niels, Vijverberg Susanne Adolescents' experiences with patient engagement in respiratory medicine Pediatric pulmonology 2021;56 (1):211-216 [PubMed]
2020
- Slob Elise M. A., Brew Bronwyn K., Vijverberg Susanne J. H., Kats Chantal J. A. R., Longo Cristina, Pijnenburg Mariëlle W., van Beijsterveldt Toos C. E. M., Dolan Conor V., Bartels Meike, Magnusson Patrick, Lichtenstein Paul, Gong Tong, Koppelman Gerard H., Almqvist Catarina, Boomsma Dorret I., Maitland-van der Zee Anke H. Early-life antibiotic use and risk of asthma and eczema: results of a discordant twin study European respiratory journal 2020;55 (4) [PubMed]
- Slob Elise M A, Brew Bronwyn K, Vijverberg Susanne J H, Dijs Talitha, van Beijsterveldt Catharina E M, Koppelman Gerard H, Bartels Meike, Dolan Conor V, Larsson Henrik, Lundström Sebastian, Lichtenstein Paul, Gong Tong, Maitland-van der Zee Anke H, Kraneveld Aletta D, Almqvist Catarina, Boomsma Dorret I Early-life antibiotic use and risk of attention-deficit hyperactivity disorder and autism spectrum disorder: results of a discordant twin study International journal of epidemiology 2020 [PubMed]
2019
- Slob Elise M., Maitland-van der Zee Anke-Hilse, Koppelman Gerard H., Pijnenburg Mariëlle W. Precision medicine in childhood asthma Current opinion in allergy and clinical immunology 2019;19 (2):141-147 [PubMed]
2018
- Liem T B Y, Slob E M A, Termote J U M, Wolfs T F W, Egberts A C G, Rademaker C M A Comparison of antibiotic dosing recommendations for neonatal sepsis from established reference sources International journal of clinical pharmacy 2018;40 (2):436-443 [PubMed]
- Zazuli Zulfan, Vijverberg Susanne, Slob Elise, Liu Geoffrey, Carleton Bruce, Veltman Joris, Baas Paul, Masereeuw Rosalinde, Maitland-van der Zee Anke-Hilse Genetic variations and cisplatin nephrotoxicity: A systematic review Frontiers in pharmacology 2018;9 [PubMed]
- Slob Elise M. A., Vijverberg Susanne J. H., Palmer Colin N. A., Zazuli Zulfan, Farzan Niloufar, Oliveri Nadia M. B., Pijnenburg Mariëlle W., Koppelman Gerard H., Maitland-van der Zee Anke H. Pharmacogenetics of inhaled long-acting beta2-agonists in asthma: A systematic review Pediatric allergy and immunology 2018;29 (7):705-714 [PubMed]
- Vijverberg Susanne J. H., Farzan Niloufar, Slob Elise M. A., Neerincx Anne H., Maitland-van der Zee Anke H. Treatment response heterogeneity in asthma: the role of genetic variation Expert review of respiratory medicine 2018;12 (1):55-65 [PubMed]
- Slob Elise M. A., Vijverberg Susanne J. H., Pijnenburg Mariëlle W., Koppelman Gerard H., der Zee Anke-Hilse Maitland-Van What do we need to transfer pharmacogenetics findings into the clinic? Pharmacogenomics 2018;19 (7):589-592 [PubMed]
2017
- Slob Elise M. A., Shulman Rob, Singer Mervyn Experience using high-dose glucose-insulin-potassium (GIK) in critically ill patients Journal of critical care 2017;41:72-77 [PubMed]