- Portela J. M. D., de Winter-Korver C. M., van Daalen S. K. M., Meißner A., de Melker A. A., Repping S., van Pelt A. M. M. Assessment of fresh and cryopreserved testicular tissues from (pre)pubertal boys during organ culture as a strategy for in vitro spermatogenesis Human reproduction (Oxford, England) 2019;34 (12):2443-2455 [PubMed]
- Eliveld Jitske, van Wely Madelon, Meicßner Andreas, Repping Sjoerd, van der Veen Fulco, van Pelt Ans M. M. The risk of TESE-induced hypogonadism: A systematic review and meta-analysis Human reproduction update 2018;24 (4):442-454 [PubMed]
- Jan Sabrina Z., Vormer Tinke L., Jongejan Aldo, Röling Michael D., Silber Sherman J., de Rooij Dirk G., Hamer Geert, Repping Sjoerd, van Pelt Ans M. M. Unraveling transcriptome dynamics in human spermatogenesis Development (Cambridge, England) 2017;144 (20):3659-3673 [PubMed]
- Nickkholgh Bita, Mizrak S. Canan, van Daalen Saskia K. M., Korver Cindy M., Sadri-Ardekani Hooman, Repping Sjoerd, van Pelt Ans M. M. Genetic and epigenetic stability of human spermatogonial stem cells during long-term culture Fertility and sterility 2014;102 (6):1700-7.e1 [PubMed]
- Sadri-Ardekani Hooman, Akhondi Mohammad A., van der Veen Fulco, Repping Sjoerd, van Pelt Ans M. M. In Vitro Propagation of Human Prepubertal Spermatogonial Stem Cells JAMA 2011;305 (23):2416-2418 [PubMed]
Education: Biology, University Utrecht
PhD degree: March 1992, Thesis: The role of retinoids in spermatogenesis
Career:
Jan 2019-onwards Head Reproductive Biology Laboratory, Amsterdam UMC, The Netherlands
Feb 2018 - onwards Professor Translational Reproductive Biology, Laboratory for Reproductive Biology, Center for Reproductive Medicine, AMC, Amsterdam, The Netherlands
Nov 2012 - Feb 2018 Associate Professor (PI) Laboratory for Reproductive Biology, Center for Reproductive Medicine, AMC, Amsterdam, The Netherlands
Apr 2007 - Nov 2012 Senior researcher/Assistant Professor Laboratory for Reproductive Biology, Center for Reproductive Medicine, AMC, Amsterdam, The Netherlands
Feb 2001 - Apr 2007 Assistant Professor Department of Endocrinology, Faculty of Science, UU, Utrecht, The Netherlands
Apr 1992 - Feb 2001 Post-doc positions UMCU, Utrecht, The Netherlands
Oct 1996 - Jan 1997 University Teacher Veterinary School, UU, Utrecht, The Netherlands
Other tasks
May 2017 Member of the international review visitation committee of the German Research Foundation (Deutsche Forschungsgemeinschaft) for DFG Research Training Group “Molecular Pathogenesis of Male Reproductive Disorders”
Feb 2016-onwards Member of the AMC EU support group
May 2015 Coordinator of the Growsperm FP7-PEOPLE-2013-ITN network
April 2013 Organizer of the annual meeting of the Dutch Society of Stem Cell Research (DSSCR)
Jan 2013-onwards Member of the Dutch Network for Fertility Preservation (NNF)
Jan 2012-onwards Member of the Board of the Dutch Society of Stem Cell Research (DSSCR) (Secretary)
July 2011-Jan 2014 Member of the Board of Reviewing Editors of scientific journal: ‘Biology of Reproduction’ 2011
June 2011-Jan 2015 Member of ESHRE Fertility Preservation Task Force Subgroup II: Fertility preservation for boys and men
Jan 2011 Member of the international review visitation committee of the German Research Foundation (Deutsche Forschungsgemeinschaft) for the evaluation of research unit FOR 1041/2
Jan 2010-April 2017 Member of the Editorial board of the Scientific Journal “Spermatogenesis”
May 2010-onwards Member of European Society for Human Reproduction and Embryology (ESHRE)
May 2008-onwards Member of the Dutch Society for Stem Cell Research (DSSCR)
March 2007-onwards Member of the International Society for In Vitro Methods (INVITROM)
Oct 2000-Febr 2005 Assistant coordinator of the EC program QLK-2000-00305
Oct 1994-dec 1997 Secretary of the Dutch/Belgium meetings “Retinoids and Development”
Grants:
FCT SR&TD SFRH/BPD/104820/2014: Effect of endocrine disruptors on spermatogenesis and testicular cancer: where does the protective role of regucalcin fit in? (Post Doc fellow Sara Carina Lima Correia) (2015-2018)
Marie Curie FP7-PEOPLE-2013-ITN 603568: Development of in vitro and in vivo strategies to avoid and cure male infertility (2014-2018) (coordinator & PI)
ZonMW TAS 116003002: Spermatogonial stem cell transplantation to restore fertility in childhood cancer survivors. (2014-2022) (PI)
KiKa 86 Restoring fertility in infertile childhood cancer survivors: bringing autotransplantation of human spermatogonial stem cells to the clinic. (2012-2014) (PI)
FCT SR&TD SFRH/BD/60945/2009: Regucalcin, a new sex steroid target gene and an apoptosis regulator in spermatogenesis? (PhD fellow Sara Carina Lima Correia) (2009-2014)
KIKA Autotransplantation of spermatogonial stem cells: preserving reproductive potential in childhood cancer patients. (2008-2012) (PI)
European Science Foundation (EuroSTELLS) Translational stem cell research: from basic biology to regenerative medicine. (04-ESTELLS-F01-029 )(2005-2008) (PI)
ZON/MW (Proefdieren Begrensd) Development of in vitro test strategies for reproductive toxicity on male germ cell lines. (3170.0067) (2004-2007) (PI)
EU (Quality of Life and Management of Living Resources) The impact of developmental exposure to weak (environmental) estrogens on the incidence of diseases in target organs later in life. (QLK-2000-00305) (2001-2005) (Assistant Coordinator & PI)
NIH (USA) In vitro development of undifferentiated spermatogonia. (HD 36476) (1999-2002) (co-PI)
Platform Alternatieven voor Dierproeven (ZON) The establishment of spermatogonial stem cell lines.(96-38) (1997-2001)(PI)
NWO-MW The regulation of proliferation and differentiation of spermatogonia and the role of vitamin A. (903-44-101) (1992-1996)
PhD students
Cpmpleted
R van den Ham* Dec 2000
M.P.A. van Bragt* June 2008
P.M. Aponte May 2009
E.A. Ahmed May 2009
G. Carlomagno* January 2011
H. Sadri-Ardekani* December 2011
M. Noordam* May 2012
J. Chikhovskaya* November 2013
L. Visser* November 2014
S.C.C. de Correia* December 2014
B. Nick Kholgh* June 2015
S.Z. Jan June 2018
C.L. Mulder June 2018
J. Onofre Mezza May 2019
Ongoing
R. Struijk (promotor: Repping/van Pelt) 2012/2019 2020
J. Eliveld (Promotor: Repping/van Pelt) 2014/2020 2020
I. Masliukaite (Promotor: Repping/van Pelt) 2015/2020 2020
J.M.D. Portela (Promotor: van Pelt/Schlatt) 2015/2020 2020
J.M. Bispo Serrano (promotor: Van Pelt) 2016/2020 2021
Q. Lei (promotor: Van Pelt) 2018/2022 2022
J.W. Bruggeman (promotor: Van Pelt) 2019/2023 2024
L.F. Baiona Alves (promotor: Van Pelt) 2019/2023 2024
Post Docs
Completed
S.C. Mizrak 2007-2012
T. Vormer 2009-2013
Ongoing
S.C. de Lima Correia 2015- now
Prof. PhD A.M.M. van Pelt (Human Reproductive Biology)
Spermatogenesis & Stem Cells: We aim to unravel the mechanism of spermatogonial stem cell renewal and differentiation up to sperm and use this knowledge to understand spermatogenic failure in men. We aim to develop a clinical application of human SSC autotransplantation as a way to preserve reproductive potential for instance in young boys diagnosed with cancer.
Postdocs
PhD S.C. de Lima Correia
MD PhD S.C. Mizrak-van Grinsven
PhD T.L. Vormer
Others
BSc A.E. Catsburg
BSc C.M. de Winter-Korver
BSc S.K.M. van Daalen
Prof. PhD S. Repping (Reproduction & Development -- Human Reproduction)
Prof. PhD F. van der Veen (Reproduction and development])
- J.M. Bispo Serrano
- J.W. Bruggeman
- J. Eliveld
- Q. Lei
- I. Masliukaite
- J.A. Onofre Meza
- R.B. Struijk
- J. van Maaren
- A.J. van Voorden
- AMC
- ZonMw